Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP13458
DateThu Jan 5 11:33:35 GMT 2012
Unique Job ID889d8db803c87069

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c3qg5A_
Top template information
PDB header:hydrolase
Chain: A: PDB Molecule:rad50;
PDBTitle: the mre11:rad50 complex forms an atp dependent molecular clamp in dna2 double-strand break repair
Confidence and coverage
Confidence: 99.9% Coverage: 32%
340 residues ( 32% of your sequence) have been modelled with 99.9% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
522 residues ( 50%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MKILSLRLKNLNSLKGEWKIDFTREPFASNGLFAITGPTGAGKTTLLDAICLALYHETPR
Secondary structure 
































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Disorder  ???





















??






























??
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   .........70.........80.........90.........100.........110.........120
Sequence  LSNVSQSQNDLMTRDTAECLAEVEFEVKGEAYRAFWSQNRARNQPDGNLQVPRVELARCA
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Disorder  ????????





























????????????









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   .........130.........140.........150.........160.........170.........180
Sequence  DGKILADKVKDKLELTATLTGLDYGRFTRSMLLSQGQFAAFLNAKPKERAELLEELTGTE
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Disorder 
?







































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   .........190.........200.........210.........220.........230.........240
Sequence  IYGQISAMVFEQHKSARTELEKLQAQASGVTLLTPEQVQSLTASLQVLTDEEKQLITAQQ
Secondary structure 

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?
???

























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   .........250.........260.........270.........280.........290.........300
Sequence  QEQQSLNWLTRQDELQQEASRRQQALQQALAEEEKAQPQLAALSLAQPARNLRPHWERIA
Secondary structure 
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   .........310.........320.........330.........340.........350.........360
Sequence  EHSAALAHIRQQIEEVNTRLQSTMALRASIRHHAAKQSAELQQQQQSLNTWLQEHDRFRQ
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   .........370.........380.........390.........400.........410.........420
Sequence  WNNEPAGWRAQFSQQTSDREHLRQWQQQLTHAEQKLNALAAITLTLTADEVATALAQHAE
Secondary structure 
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   .........430.........440.........450.........460.........470.........480
Sequence  QRPLRQHLVALHGQIVPQQKRLAQLQVAIQNVTQEQTQRNAALNEMRQRYKEKTQQLADV
Secondary structure 
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   .........490.........500.........510.........520.........530.........540
Sequence  KTICEQEARIKTLEAQRAQLQAGQPCPLCGSTSHPAVEAYQALEPGVNQSRLLALENEVK
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????????
?


?

??????????????











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   .........550.........560.........570.........580.........590.........600
Sequence  KLGEEGATLRGQLDAITKQLQRDENEAQSLRQDEQALTQQWQAVTASLNITLQPLDDIQP
Secondary structure 
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   .........610.........620.........630.........640.........650.........660
Sequence  WLDAQDEHERQLRLLSQRHELQGQIAAHNQQIIQYQQQIEQRQQLLLTTLTGYALTLPQE
Secondary structure 
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   .........670.........680.........690.........700.........710.........720
Sequence  DEEESWLATRQQEAQSWQQRQNELTALQNRIQQLTPILETLPQSDELPHCEETVVLENWR
Secondary structure 
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   .........730.........740.........750.........760.........770.........780
Sequence  QVHEQCLALHSQQQTLQQQDVLAAQSLQKAQAQFDTALQASVFDDQQAFLAALMDEQTLT
Secondary structure 







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??????














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   .........790.........800.........810.........820.........830.........840
Sequence  QLEQLKQNLENQRRQAQTLVTQTAETLAQHQQHRPDDGLALTVTVEQIQQELAQTHQKLR
Secondary structure 




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   .........850.........860.........870.........880.........890.........900
Sequence  ENTTSQGEIRQQLKQDADNRQQQQTLMQQIAQMTQQVEDWGYLNSLIGSKEGDKFRKFAQ
Secondary structure 






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??????







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   .........910.........920.........930.........940.........950.........960
Sequence  GLTLDNLVHLANQQLTRLHGRYLLQRKASEALEVEVVDTWQADAVRDTRTLSGGESFLVS
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?
?






????















??
?








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   .........970.........980.........990.........1000.........1010.........1020
Sequence  LALALALSDLVSHKTRIDSLFLDEGFGTLDSETLDTALDALDALNASGKTIGVISHVEAM
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??
???










































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   .........1030.........1040........
Sequence  KERIPVQIKVKKINGLGYSKLESTFAVK
Secondary structure 










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Disorder 











?????








??
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 3qg5 chain A

3D model

Region: 1 - 363
Aligned: 340
Modelled: 362
Confidence: 99.9%
Identity: 17%
PDB header:hydrolase
Chain: A: PDB Molecule:rad50;
PDBTitle: the mre11:rad50 complex forms an atp dependent molecular clamp in dna2 double-strand break repair

Phyre2

PDB 1ii8 chain A

3D model

Region: 1 - 211
Aligned: 195
Modelled: 209
Confidence: 99.9%
Identity: 20%
PDB header:replication
Chain: A: PDB Molecule:rad50 abc-atpase;
PDBTitle: crystal structure of the p. furiosus rad50 atpase domain

Phyre2

PDB 1xex chain A

3D model

Region: 2 - 177
Aligned: 160
Modelled: 176
Confidence: 99.9%
Identity: 19%
PDB header:cell cycle
Chain: A: PDB Molecule:smc protein;
PDBTitle: structural biochemistry of atp-driven dimerization and dna2 stimulated activation of smc atpases.

Phyre2

PDB 3auy chain B

3D model

Region: 1 - 256
Aligned: 232
Modelled: 244
Confidence: 99.9%
Identity: 22%
PDB header:recombination
Chain: B: PDB Molecule:dna double-strand break repair rad50 atpase;
PDBTitle: crystal structure of rad50 bound to adp

Phyre2

PDB 3qku chain B

3D model

Region: 1 - 194
Aligned: 179
Modelled: 191
Confidence: 99.9%
Identity: 21%
PDB header:replication
Chain: B: PDB Molecule:dna double-strand break repair rad50 atpase;
PDBTitle: mre11 rad50 binding domain in complex with rad50 and amp-pnp

Phyre2

PDB 1ii8 chain B

3D model

Region: 864 - 1041
Aligned: 170
Modelled: 173
Confidence: 99.9%
Identity: 22%
PDB header:replication
Chain: B: PDB Molecule:rad50 abc-atpase;
PDBTitle: crystal structure of the p. furiosus rad50 atpase domain

Phyre2

PDB 1f2u chain D

3D model

Region: 901 - 1043
Aligned: 138
Modelled: 143
Confidence: 99.8%
Identity: 26%
PDB header:replication
Chain: D: PDB Molecule:rad50 abc-atpase;
PDBTitle: crystal structure of rad50 abc-atpase

Phyre2

PDB 1e69 chain A

3D model

Region: 1 - 176
Aligned: 147
Modelled: 153
Confidence: 99.8%
Identity: 26%
Fold: P-loop containing nucleoside triphosphate hydrolases
Superfamily: P-loop containing nucleoside triphosphate hydrolases
Family: ABC transporter ATPase domain-like

Phyre2

PDB 1us8 chain A

3D model

Region: 1 - 162
Aligned: 129
Modelled: 144
Confidence: 99.8%
Identity: 29%
PDB header:dna repair
Chain: A: PDB Molecule:dna double-strand break repair rad50 atpase;
PDBTitle: the rad50 signature motif: essential to atp binding and2 biological function

Phyre2

PDB 1xex chain B

3D model

Region: 900 - 1043
Aligned: 137
Modelled: 144
Confidence: 99.7%
Identity: 19%
PDB header:cell cycle
Chain: B: PDB Molecule:smc protein;
PDBTitle: structural biochemistry of atp-driven dimerization and dna2 stimulated activation of smc atpases.

Phyre2

PDB 1w1w chain A

3D model

Region: 2 - 188
Aligned: 153
Modelled: 169
Confidence: 99.7%
Identity: 22%
Fold: P-loop containing nucleoside triphosphate hydrolases
Superfamily: P-loop containing nucleoside triphosphate hydrolases
Family: ABC transporter ATPase domain-like

Phyre2

PDB 2o5v chain A

3D model

Region: 1 - 99
Aligned: 87
Modelled: 99
Confidence: 99.6%
Identity: 26%
PDB header:replication/recombination
Chain: A: PDB Molecule:dna replication and repair protein recf;
PDBTitle: recombination mediator recf

Phyre2

PDB 1qhl chain A

3D model

Region: 2 - 196
Aligned: 187
Modelled: 195
Confidence: 99.6%
Identity: 17%
Fold: P-loop containing nucleoside triphosphate hydrolases
Superfamily: P-loop containing nucleoside triphosphate hydrolases
Family: ABC transporter ATPase domain-like

Phyre2

PDB 3pih chain A

3D model

Region: 946 - 1041
Aligned: 91
Modelled: 96
Confidence: 99.2%
Identity: 26%
PDB header:hydrolase/dna
Chain: A: PDB Molecule:uvrabc system protein a;
PDBTitle: t. maritima uvra in complex with fluorescein-modified dna

Phyre2

PDB 3bk7 chain A

3D model

Region: 946 - 1048
Aligned: 95
Modelled: 103
Confidence: 99.2%
Identity: 25%
PDB header:hydrolyase/translation
Chain: A: PDB Molecule:abc transporter atp-binding protein;
PDBTitle: structure of the complete abce1/rnaase-l inhibitor protein2 from pyrococcus abysii

Phyre2

PDB 1yqt chain A

3D model

Region: 946 - 1041
Aligned: 88
Modelled: 96
Confidence: 99.2%
Identity: 30%
PDB header:hydrolyase/translation
Chain: A: PDB Molecule:rnase l inhibitor;
PDBTitle: rnase-l inhibitor

Phyre2

PDB 2vf7 chain B

3D model

Region: 946 - 1035
Aligned: 85
Modelled: 90
Confidence: 99.2%
Identity: 24%
PDB header:dna-binding protein
Chain: B: PDB Molecule:excinuclease abc, subunit a.;
PDBTitle: crystal structure of uvra2 from deinococcus radiodurans

Phyre2

PDB 2ygr chain D

3D model

Region: 946 - 1041
Aligned: 91
Modelled: 96
Confidence: 99.1%
Identity: 30%
PDB header:hydrolase
Chain: D: PDB Molecule:uvrabc system protein a;
PDBTitle: mycobacterium tuberculosis uvra

Phyre2

PDB 3ozx chain A

3D model

Region: 946 - 1048
Aligned: 94
Modelled: 103
Confidence: 99.0%
Identity: 20%
PDB header:hydrolase, translation
Chain: A: PDB Molecule:rnase l inhibitor;
PDBTitle: crystal structure of abce1 of sulfolubus solfataricus (-fes domain)

Phyre2

PDB 2pcj chain B

3D model

Region: 946 - 1031
Aligned: 78
Modelled: 86
Confidence: 98.9%
Identity: 33%
PDB header:hydrolase
Chain: B: PDB Molecule:lipoprotein-releasing system atp-binding protein lold;
PDBTitle: crystal structure of abc transporter (aq_297) from aquifex aeolicus2 vf5

Phyre2
1

c3qg5A_
2

c1ii8A_
3

c1xexA_
4

c3auyB_
5

c3qkuB_
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c1ii8B_
7

c1f2uD_
8

d1e69a_
9

c1us8A_
10

c1xexB_
11

d1w1wa_
12

c2o5vA_
13

d1qhla_
14

c3pihA_
15

c3bk7A_
16

c1yqtA_
17

c2vf7B_
18

c2ygrD_
19

c3ozxA_
20

c2pcjB_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c3qg5A_



99.9 17 PDB header:hydrolase
Chain: A: PDB Molecule:rad50;
PDBTitle: the mre11:rad50 complex forms an atp dependent molecular clamp in dna2 double-strand break repair
2c1ii8A_



99.9 20 PDB header:replication
Chain: A: PDB Molecule:rad50 abc-atpase;
PDBTitle: crystal structure of the p. furiosus rad50 atpase domain
3c1xexA_



99.9 19 PDB header:cell cycle
Chain: A: PDB Molecule:smc protein;
PDBTitle: structural biochemistry of atp-driven dimerization and dna2 stimulated activation of smc atpases.
4c3auyB_



99.9 22 PDB header:recombination
Chain: B: PDB Molecule:dna double-strand break repair rad50 atpase;
PDBTitle: crystal structure of rad50 bound to adp
5c3qkuB_



99.9 21 PDB header:replication
Chain: B: PDB Molecule:dna double-strand break repair rad50 atpase;
PDBTitle: mre11 rad50 binding domain in complex with rad50 and amp-pnp
6c1ii8B_



99.9 22 PDB header:replication
Chain: B: PDB Molecule:rad50 abc-atpase;
PDBTitle: crystal structure of the p. furiosus rad50 atpase domain
7c1f2uD_



99.8 26 PDB header:replication
Chain: D: PDB Molecule:rad50 abc-atpase;
PDBTitle: crystal structure of rad50 abc-atpase
8d1e69a_



99.8 26 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:ABC transporter ATPase domain-like
9c1us8A_



99.8 29 PDB header:dna repair
Chain: A: PDB Molecule:dna double-strand break repair rad50 atpase;
PDBTitle: the rad50 signature motif: essential to atp binding and2 biological function
10c1xexB_



99.7 19 PDB header:cell cycle
Chain: B: PDB Molecule:smc protein;
PDBTitle: structural biochemistry of atp-driven dimerization and dna2 stimulated activation of smc atpases.
11d1w1wa_



99.7 22 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:ABC transporter ATPase domain-like
12c2o5vA_



99.6 26 PDB header:replication/recombination
Chain: A: PDB Molecule:dna replication and repair protein recf;
PDBTitle: recombination mediator recf
13d1qhla_



99.6 17 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:ABC transporter ATPase domain-like
14c3pihA_



99.2 26 PDB header:hydrolase/dna
Chain: A: PDB Molecule:uvrabc system protein a;
PDBTitle: t. maritima uvra in complex with fluorescein-modified dna
15c3bk7A_



99.2 25 PDB header:hydrolyase/translation
Chain: A: PDB Molecule:abc transporter atp-binding protein;
PDBTitle: structure of the complete abce1/rnaase-l inhibitor protein2 from pyrococcus abysii
16c1yqtA_



99.2 30 PDB header:hydrolyase/translation
Chain: A: PDB Molecule:rnase l inhibitor;
PDBTitle: rnase-l inhibitor
17c2vf7B_



99.2 24 PDB header:dna-binding protein
Chain: B: PDB Molecule:excinuclease abc, subunit a.;
PDBTitle: crystal structure of uvra2 from deinococcus radiodurans
18c2ygrD_



99.1 30 PDB header:hydrolase
Chain: D: PDB Molecule:uvrabc system protein a;
PDBTitle: mycobacterium tuberculosis uvra
19c3ozxA_



99.0 20 PDB header:hydrolase, translation
Chain: A: PDB Molecule:rnase l inhibitor;
PDBTitle: crystal structure of abce1 of sulfolubus solfataricus (-fes domain)
20c2pcjB_



98.9 33 PDB header:hydrolase
Chain: B: PDB Molecule:lipoprotein-releasing system atp-binding protein lold;
PDBTitle: crystal structure of abc transporter (aq_297) from aquifex aeolicus2 vf5
21c3dhwC_



not modelled 98.9 35 PDB header:membrane protein/hydrolase
Chain: C: PDB Molecule:methionine import atp-binding protein metn;
PDBTitle: crystal structure of methionine importer metni
22c2yl4A_



not modelled 98.8 30 PDB header:membrane protein
Chain: A: PDB Molecule:atp-binding cassette sub-family b member 10,
PDBTitle: structure of the human mitochondrial abc transporter, abcb10
23d1g6ha_



not modelled 98.8 24 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:ABC transporter ATPase domain-like
24d1b0ua_



not modelled 98.8 30 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:ABC transporter ATPase domain-like
25c2olkD_



not modelled 98.8 25 PDB header:hydrolase
Chain: D: PDB Molecule:amino acid abc transporter;
PDBTitle: abc protein artp in complex with adp-beta-s
26c2nq2C_



not modelled 98.8 29 PDB header:metal transport
Chain: C: PDB Molecule:hypothetical abc transporter atp-binding protein
PDBTitle: an inward-facing conformation of a putative metal-chelate2 type abc transporter.
27c1vciA_



not modelled 98.8 23 PDB header:transport protein
Chain: A: PDB Molecule:sugar-binding transport atp-binding protein;
PDBTitle: crystal structure of the atp-binding cassette of multisugar2 transporter from pyrococcus horikoshii ot3 complexed with3 atp
28c2iw3B_



not modelled 98.8 24 PDB header:translation
Chain: B: PDB Molecule:elongation factor 3a;
PDBTitle: elongation factor 3 in complex with adp
29c2d62A_



not modelled 98.8 26 PDB header:sugar binding protein
Chain: A: PDB Molecule:multiple sugar-binding transport atp-binding
PDBTitle: crystal structure of multiple sugar binding transport atp-2 binding protein
30d1vpla_



not modelled 98.8 26 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:ABC transporter ATPase domain-like
31c3fvqB_



not modelled 98.8 32 PDB header:hydrolase
Chain: B: PDB Molecule:fe(3+) ions import atp-binding protein fbpc;
PDBTitle: crystal structure of the nucleotide binding domain fbpc2 complexed with atp
32c2yz2B_



not modelled 98.8 31 PDB header:hydrolase
Chain: B: PDB Molecule:putative abc transporter atp-binding protein tm_0222;
PDBTitle: crystal structure of the abc transporter in the cobalt transport2 system
33c1oxtB_



not modelled 98.8 35 PDB header:transport protein
Chain: B: PDB Molecule:abc transporter, atp binding protein;
PDBTitle: crystal structure of glcv, the abc-atpase of the glucose abc2 transporter from sulfolobus solfataricus
34c2hydB_



not modelled 98.8 28 PDB header:transport protein
Chain: B: PDB Molecule:abc transporter homolog;
PDBTitle: multidrug abc transporter sav1866
35d1l2ta_



not modelled 98.7 30 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:ABC transporter ATPase domain-like
36d1v43a3



not modelled 98.7 23 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:ABC transporter ATPase domain-like
37d2hyda1



not modelled 98.7 25 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:ABC transporter ATPase domain-like
38c3eukC_



not modelled 98.7 19 PDB header:cell cycle
Chain: C: PDB Molecule:chromosome partition protein mukb, linker;
PDBTitle: crystal structure of muke-mukf(residues 292-443)-mukb(head2 domain)-atpgammas complex, asymmetric dimer
39d3dhwc1



not modelled 98.7 35 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:ABC transporter ATPase domain-like
40c2pjzA_



not modelled 98.7 25 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:hypothetical protein st1066;
PDBTitle: the crystal structure of putative cobalt transport atp-2 binding protein (cbio-2), st1066
41c2yyzA_



not modelled 98.7 28 PDB header:transport protein
Chain: A: PDB Molecule:sugar abc transporter, atp-binding protein;
PDBTitle: crystal structure of sugar abc transporter, atp-binding protein
42c3gfoA_



not modelled 98.7 25 PDB header:atp binding protein
Chain: A: PDB Molecule:cobalt import atp-binding protein cbio 1;
PDBTitle: structure of cbio1 from clostridium perfringens: part of2 the abc transporter complex cbionq.
43c2d2fA_



not modelled 98.7 21 PDB header:protein binding
Chain: A: PDB Molecule:sufc protein;
PDBTitle: crystal structure of atypical cytoplasmic abc-atpase sufc from thermus2 thermophilus hb8
44d1g2912



not modelled 98.7 24 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:ABC transporter ATPase domain-like
45d3b60a1



not modelled 98.7 31 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:ABC transporter ATPase domain-like
46d1jj7a_



not modelled 98.7 21 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:ABC transporter ATPase domain-like
47d1ji0a_



not modelled 98.7 24 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:ABC transporter ATPase domain-like
48d2pmka1



not modelled 98.7 25 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:ABC transporter ATPase domain-like
49c1z47B_



not modelled 98.7 26 PDB header:ligand binding protein
Chain: B: PDB Molecule:putative abc-transporter atp-binding protein;
PDBTitle: structure of the atpase subunit cysa of the putative2 sulfate atp-binding cassette (abc) transporter from3 alicyclobacillus acidocaldarius
50c2it1B_



not modelled 98.7 30 PDB header:transport protein
Chain: B: PDB Molecule:362aa long hypothetical maltose/maltodextrin
PDBTitle: structure of ph0203 protein from pyrococcus horikoshii
51c2r6fA_



not modelled 98.7 31 PDB header:hydrolase
Chain: A: PDB Molecule:excinuclease abc subunit a;
PDBTitle: crystal structure of bacillus stearothermophilus uvra
52d1mv5a_



not modelled 98.6 29 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:ABC transporter ATPase domain-like
53d3d31a2



not modelled 98.6 36 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:ABC transporter ATPase domain-like
54c2cbzA_



not modelled 98.6 24 PDB header:transport
Chain: A: PDB Molecule:multidrug resistance-associated protein 1;
PDBTitle: structure of the human multidrug resistance protein 12 nucleotide binding domain 1
55d1oxxk2



not modelled 98.6 33 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:ABC transporter ATPase domain-like
56d1r0wa_



not modelled 98.6 24 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:ABC transporter ATPase domain-like
57c3g5uB_



not modelled 98.6 32 PDB header:membrane protein
Chain: B: PDB Molecule:multidrug resistance protein 1a;
PDBTitle: structure of p-glycoprotein reveals a molecular basis for2 poly-specific drug binding
58c3b5xB_



not modelled 98.6 30 PDB header:membrane protein
Chain: B: PDB Molecule:lipid a export atp-binding/permease protein msba;
PDBTitle: crystal structure of msba from vibrio cholerae
59c3b5wE_



not modelled 98.6 31 PDB header:membrane protein
Chain: E: PDB Molecule:lipid a export atp-binding/permease protein msba;
PDBTitle: crystal structure of eschericia coli msba
60c3d31B_



not modelled 98.6 36 PDB header:transport protein
Chain: B: PDB Molecule:sulfate/molybdate abc transporter, atp-binding
PDBTitle: modbc from methanosarcina acetivorans
61c3nhaA_



not modelled 98.6 25 PDB header:transport protein
Chain: A: PDB Molecule:atp-binding cassette sub-family b member 6, mitochondrial;
PDBTitle: nucleotide binding domain of human abcb6 (adp mg bound structure)
62d1xmia_



not modelled 98.6 24 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:ABC transporter ATPase domain-like
63c2pzfB_



not modelled 98.5 26 PDB header:hydrolase
Chain: B: PDB Molecule:cystic fibrosis transmembrane conductance regulator;
PDBTitle: minimal human cftr first nucleotide binding domain as a head-to-tail2 dimer with delta f508
64d2onka1



not modelled 98.5 25 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:ABC transporter ATPase domain-like
65d1l7vc_



not modelled 98.5 30 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:ABC transporter ATPase domain-like
66c2d3wB_



not modelled 98.5 20 PDB header:biosynthetic protein
Chain: B: PDB Molecule:probable atp-dependent transporter sufc;
PDBTitle: crystal structure of escherichia coli sufc, an atpase2 compenent of the suf iron-sulfur cluster assembly machinery
67c1q1bD_



not modelled 98.5 22 PDB header:transport protein
Chain: D: PDB Molecule:maltose/maltodextrin transport atp-binding protein malk;
PDBTitle: crystal structure of e. coli malk in the nucleotide-free form
68d1pf4a1



not modelled 98.4 33 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:ABC transporter ATPase domain-like
69c2ihyB_



not modelled 98.3 29 PDB header:hydrolase
Chain: B: PDB Molecule:abc transporter, atp-binding protein;
PDBTitle: structure of the staphylococcus aureus putative atpase subunit of an2 atp-binding cassette (abc) transporter
70c3gd7C_



not modelled 98.3 24 PDB header:hydrolase
Chain: C: PDB Molecule:fusion complex of cystic fibrosis transmembrane
PDBTitle: crystal structure of human nbd2 complexed with n6-2 phenylethyl-atp (p-atp)
71d1sgwa_



not modelled 98.2 21 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:ABC transporter ATPase domain-like
72c2ghiD_



not modelled 98.0 25 PDB header:transport protein
Chain: D: PDB Molecule:transport protein;
PDBTitle: crystal structure of plasmodium yoelii multidrug resistance2 protein 2
73d2awna2



not modelled 97.9 16 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:ABC transporter ATPase domain-like
74d1vmaa2



not modelled 97.7 22 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Nitrogenase iron protein-like
75d1np6a_



not modelled 97.6 43 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Nitrogenase iron protein-like
76d2qy9a2



not modelled 97.6 19 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Nitrogenase iron protein-like
77d1okkd2



not modelled 97.5 20 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Nitrogenase iron protein-like
78c2j41A_



not modelled 97.5 40 PDB header:transferase
Chain: A: PDB Molecule:guanylate kinase;
PDBTitle: crystal structure of staphylococcus aureus guanylate2 monophosphate kinase
79c3tauB_



not modelled 97.4 40 PDB header:transferase
Chain: B: PDB Molecule:guanylate kinase;
PDBTitle: crystal structure of a putative guanylate monophosphaste kinase from2 listeria monocytogenes egd-e
80d1ls1a2



not modelled 97.4 27 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Nitrogenase iron protein-like
81c3a4mB_



not modelled 97.3 35 PDB header:transferase
Chain: B: PDB Molecule:l-seryl-trna(sec) kinase;
PDBTitle: crystal structure of archaeal o-phosphoseryl-trna(sec)2 kinase
82d1qzxa3



not modelled 97.1 24 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Nitrogenase iron protein-like
83d2i3ba1



not modelled 97.0 47 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:RecA protein-like (ATPase-domain)
84d1ye8a1



not modelled 97.0 53 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:RecA protein-like (ATPase-domain)
85d1cr2a_



not modelled 96.9 19 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:RecA protein-like (ATPase-domain)
86d1ewqa2



not modelled 96.9 41 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:ABC transporter ATPase domain-like
87d1znwa1



not modelled 96.7 25 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Nucleotide and nucleoside kinases
88c1ewqA_



not modelled 96.7 44 PDB header:replication/dna
Chain: A: PDB Molecule:dna mismatch repair protein muts;
PDBTitle: crystal structure taq muts complexed with a heteroduplex2 dna at 2.2 a resolution
89d1wb9a2



not modelled 96.7 29 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:ABC transporter ATPase domain-like
90c2o8bA_



not modelled 96.6 27 PDB header:dna binding protein/dna
Chain: A: PDB Molecule:dna mismatch repair protein msh2;
PDBTitle: human mutsalpha (msh2/msh6) bound to adp and a g t mispair
91c2o8dB_



not modelled 96.6 31 PDB header:dna binding protein/dna
Chain: B: PDB Molecule:dna mismatch repair protein msh6;
PDBTitle: human mutsalpha (msh2/msh6) bound to adp and a g du mispair
92c3jvvA_



not modelled 96.6 50 PDB header:atp binding protein
Chain: A: PDB Molecule:twitching mobility protein;
PDBTitle: crystal structure of p. aeruginosa pilt with bound amp-pcp
93d1ki9a_



not modelled 96.6 21 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Nucleotide and nucleoside kinases
94d1p9ra_



not modelled 96.6 48 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:RecA protein-like (ATPase-domain)
95c2cnwF_



not modelled 96.6 18 PDB header:signal recognition
Chain: F: PDB Molecule:cell division protein ftsy;
PDBTitle: gdpalf4 complex of the srp gtpases ffh and ftsy
96d1s96a_



not modelled 96.6 40 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Nucleotide and nucleoside kinases
97c2j7pA_



not modelled 96.5 24 PDB header:signal recognition
Chain: A: PDB Molecule:signal recognition particle protein;
PDBTitle: gmppnp-stabilized ng domain complex of the srp gtpases ffh2 and ftsy
98c2yhsA_



not modelled 96.5 18 PDB header:cell cycle
Chain: A: PDB Molecule:cell division protein ftsy;
PDBTitle: structure of the e. coli srp receptor ftsy
99c3thxB_



not modelled 96.5 31 PDB header:dna binding protein/dna
Chain: B: PDB Molecule:dna mismatch repair protein msh3;
PDBTitle: human mutsbeta complexed with an idl of 3 bases (loop3) and adp
100c3b9qA_



not modelled 96.5 30 PDB header:protein transport
Chain: A: PDB Molecule:chloroplast srp receptor homolog, alpha subunit
PDBTitle: the crystal structure of cpftsy from arabidopsis thaliana
101c1u9iA_



not modelled 96.5 19 PDB header:circadian clock protein
Chain: A: PDB Molecule:kaic;
PDBTitle: crystal structure of circadian clock protein kaic with phosphorylation2 sites
102c3geiB_



not modelled 96.5 44 PDB header:hydrolase
Chain: B: PDB Molecule:trna modification gtpase mnme;
PDBTitle: crystal structure of mnme from chlorobium tepidum in complex2 with gcp
103d1zp6a1



not modelled 96.4 30 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Atu3015-like
104c1wbdA_



not modelled 96.4 31 PDB header:dna-binding
Chain: A: PDB Molecule:dna mismatch repair protein muts;
PDBTitle: crystal structure of e. coli dna mismatch repair enzyme2 muts, e38q mutant, in complex with a g.t mismatch
105c2og2A_



not modelled 96.4 30 PDB header:protein transport
Chain: A: PDB Molecule:putative signal recognition particle receptor;
PDBTitle: crystal structure of chloroplast ftsy from arabidopsis2 thaliana
106d1sxje2



not modelled 96.4 25 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Extended AAA-ATPase domain
107c2f1rA_



not modelled 96.4 35 PDB header:biosynthetic protein
Chain: A: PDB Molecule:molybdopterin-guanine dinucleotide biosynthesis
PDBTitle: crystal structure of molybdopterin-guanine biosynthesis2 protein b (mobb)
108c1ewrA_



not modelled 96.4 44 PDB header:hydrolase
Chain: A: PDB Molecule:dna mismatch repair protein muts;
PDBTitle: crystal structure of taq muts
109c2qy9A_



not modelled 96.4 18 PDB header:protein transport
Chain: A: PDB Molecule:cell division protein ftsy;
PDBTitle: structure of the ng+1 construct of the e. coli srp receptor2 ftsy
110d1sxja2



not modelled 96.4 28 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Extended AAA-ATPase domain
111d1yrba1



not modelled 96.3 35 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Nitrogenase iron protein-like
112c1znyA_



not modelled 96.3 25 PDB header:transferase
Chain: A: PDB Molecule:guanylate kinase;
PDBTitle: crystal structure of mycobacterium tuberculosis guanylate kinase in2 complex with gdp
113c2eyuA_



not modelled 96.3 38 PDB header:protein transport
Chain: A: PDB Molecule:twitching motility protein pilt;
PDBTitle: the crystal structure of the c-terminal domain of aquifex2 aeolicus pilt
114c1wxqA_



not modelled 96.3 26 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:gtp-binding protein;
PDBTitle: crystal structure of gtp binding protein from pyrococcus horikoshii2 ot3
115c2gzaB_



not modelled 96.2 39 PDB header:hydrolase
Chain: B: PDB Molecule:type iv secretion system protein virb11;
PDBTitle: crystal structure of the virb11 atpase from the brucella suis type iv2 secretion system in complex with sulphate
116c1zu4A_



not modelled 96.2 24 PDB header:protein transport
Chain: A: PDB Molecule:ftsy;
PDBTitle: crystal structure of ftsy from mycoplasma mycoides- space2 group p21212
117d1g6oa_



not modelled 96.2 38 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:RecA protein-like (ATPase-domain)
118c3neyC_



not modelled 96.2 20 PDB header:membrane protein
Chain: C: PDB Molecule:55 kda erythrocyte membrane protein;
PDBTitle: crystal structure of the kinase domain of mpp1/p55
119c2gszE_



not modelled 96.2 43 PDB header:protein transport
Chain: E: PDB Molecule:twitching motility protein pilt;
PDBTitle: structure of a. aeolicus pilt with 6 monomers per2 asymmetric unit
120c1vmaA_



not modelled 96.1 21 PDB header:protein transport
Chain: A: PDB Molecule:cell division protein ftsy;
PDBTitle: crystal structure of cell division protein ftsy (tm0570) from2 thermotoga maritima at 1.60 a resolution

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0