Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	K	S	P	A	P	S	R	P	Q	K	M	A	L	I	P	A	C	I	F	L	C	F	A	A	L	S	V	Q	A	E	E	T	P	V	T	P	Q	P	P	D	I	L	L	G	P	L	F	N	D	V	Q	N	A	K	L	F	P	D	Q
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?															?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		K	T	F	A	D	A	V	P	N	S	D	P	L	M	I	L	A	D	Y	R	M	Q	Q	N	Q	S	G	F	D	L	R	H	F	V	N	V	N	F	T	L	P	K	E	G	E	K	Y	V	P	P	E	G	Q	S	L	R	E	H	I	D
Secondary structure
SS confidence
Disorder																							?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		G	L	W	P	V	L	T	R	S	T	E	N	T	E	K	W	D	S	L	L	P	L	P	E	P	Y	V	V	P	G	G	R	F	R	E	V	Y	Y	W	D	S	Y	F	T	M	L	G	L	A	E	S	G	H	W	D	K	V	A	D	M
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		V	A	N	F	A	H	E	I	D	T	Y	G	H	I	P	N	G	N	R	S	Y	Y	L	S	R	S	Q	P	P	F	F	A	L	M	V	E	L	L	A	Q	H	E	G	D	A	A	L	K	Q	Y	L	P	Q	M	Q	K	E	Y	A	Y
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		W	M	D	G	V	E	N	L	Q	A	G	Q	Q	E	K	R	V	V	K	L	Q	D	G	T	L	L	N	R	Y	W	D	D	R	D	T	P	R	P	E	S	W	V	E	D	I	A	T	A	K	S	N	P	N	R	P	A	T	E	I	Y
Secondary structure
SS confidence
Disorder								?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		R	D	L	R	S	A	A	A	S	G	W	D	F	S	S	R	W	M	D	N	P	Q	Q	L	N	T	L	R	T	T	S	I	V	P	V	D	L	N	S	L	M	F	K	M	E	K	I	L	A	R	A	S	K	A	A	G	D	N	A	M
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		A	N	Q	Y	E	T	L	A	N	A	R	Q	K	G	I	E	K	Y	L	W	N	D	Q	Q	G	W	Y	A	D	Y	D	L	K	S	H	K	V	R	N	Q	L	T	A	A	A	L	F	P	L	Y	V	N	A	A	A	K	D	R	A	N
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		K	M	A	T	A	T	K	T	H	L	L	Q	P	G	G	L	N	T	T	S	V	K	S	G	Q	Q	W	D	A	P	N	G	W	A	P	L	Q	W	V	A	T	E	G	L	Q	N	Y	G	Q	K	E	V	A	M	D	I	S	W	H	F
Secondary structure
SS confidence
Disorder																								?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540
Sequence		L	T	N	V	Q	H	T	Y	D	R	E	K	K	L	V	E	K	Y	D	V	S	T	T	G	T	G	G	G	G	G	E	Y	P	L	Q	D	G	F	G	W	T	N	G	V	T	L	K	M	L	D	L	I	C	P	K	E	Q	P	C	D
Secondary structure
SS confidence
Disorder																										?	?	?	?	?	?																												?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.
Sequence		N	V	P	A	T	R	P	T	V	K	S	A	T	T	Q	P	S	T	K	E	A	Q	P	T	P
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2jg0 chain A Region: 37 - 547 Aligned: 507 Modelled: 511 Confidence: 100.0% Identity: 99% PDB header:hydrolase Chain: A: PDB Molecule:periplasmic trehalase; PDBTitle: family 37 trehalase from escherichia coli in complex with 1-2 thiatrehazolin Phyre2 PDB 2jg0 chain A domain 1 Region: 37 - 547 Aligned: 507 Modelled: 511 Confidence: 100.0% Identity: 99% Fold: alpha/alpha toroid Superfamily: Six-hairpin glycosidases Family: Trehalase-like Phyre2 PDB 3c67 chain B Region: 142 - 535 Aligned: 384 Modelled: 394 Confidence: 100.0% Identity: 17% PDB header:hydrolase Chain: B: PDB Molecule:uncharacterized protein ygjk; PDBTitle: escherichia coli k12 ygjk in a complexed with glucose Phyre2 PDB 2z07 chain A Region: 143 - 528 Aligned: 348 Modelled: 371 Confidence: 100.0% Identity: 21% PDB header:hydrolase Chain: A: PDB Molecule:putative uncharacterized protein ttha0978; PDBTitle: crystal structure of uncharacterized conserved protein from2 thermus thermophilus hb8 Phyre2 PDB 2okx chain B Region: 153 - 530 Aligned: 297 Modelled: 302 Confidence: 99.9% Identity: 17% PDB header:hydrolase Chain: B: PDB Molecule:rhamnosidase b; PDBTitle: crystal structure of gh78 family rhamnosidase of bacillus sp. gl1 at2 1.9 a Phyre2 PDB 1v7w chain A Region: 143 - 544 Aligned: 338 Modelled: 348 Confidence: 99.9% Identity: 17% PDB header:transferase Chain: A: PDB Molecule:chitobiose phosphorylase; PDBTitle: crystal structure of vibrio proteolyticus chitobiose phosphorylase in2 complex with glcnac Phyre2 PDB 1v7w chain A domain 1 Region: 143 - 532 Aligned: 333 Modelled: 336 Confidence: 99.9% Identity: 17% Fold: alpha/alpha toroid Superfamily: Six-hairpin glycosidases Family: Glycosyltransferase family 36 C-terminal domain Phyre2 PDB 3cih chain A Region: 163 - 530 Aligned: 282 Modelled: 291 Confidence: 99.9% Identity: 13% PDB header:hydrolase Chain: A: PDB Molecule:putative alpha-rhamnosidase; PDBTitle: crystal structure of a putative alpha-rhamnosidase from2 bacteroides thetaiotaomicron Phyre2 PDB 2cqt chain A Region: 150 - 479 Aligned: 282 Modelled: 288 Confidence: 99.8% Identity: 14% PDB header:transferase Chain: A: PDB Molecule:cellobiose phosphorylase; PDBTitle: crystal structure of cellvibrio gilvus cellobiose phosphorylase2 crystallized from sodium/potassium phosphate Phyre2 PDB 1lf6 chain A domain 1 Region: 144 - 532 Aligned: 297 Modelled: 308 Confidence: 99.8% Identity: 12% Fold: alpha/alpha toroid Superfamily: Six-hairpin glycosidases Family: Bacterial glucoamylase C-terminal domain-like Phyre2 PDB 1lf6 chain A Region: 142 - 529 Aligned: 295 Modelled: 307 Confidence: 99.4% Identity: 14% PDB header:hydrolase Chain: A: PDB Molecule:glucoamylase; PDBTitle: crystal structure of bacterial glucoamylase Phyre2 PDB 1ulv chain A domain 1 Region: 142 - 529 Aligned: 310 Modelled: 310 Confidence: 99.3% Identity: 15% Fold: alpha/alpha toroid Superfamily: Six-hairpin glycosidases Family: Bacterial glucoamylase C-terminal domain-like Phyre2 PDB 2fba chain A domain 1 Region: 156 - 530 Aligned: 291 Modelled: 301 Confidence: 98.5% Identity: 18% Fold: alpha/alpha toroid Superfamily: Six-hairpin glycosidases Family: Glucoamylase Phyre2 PDB 2vn4 chain A Region: 156 - 565 Aligned: 322 Modelled: 336 Confidence: 98.1% Identity: 17% PDB header:hydrolase Chain: A: PDB Molecule:glucoamylase; PDBTitle: glycoside hydrolase family 15 glucoamylase from hypocrea2 jecorina Phyre2 PDB 1gai chain A Region: 156 - 564 Aligned: 322 Modelled: 335 Confidence: 98.0% Identity: 20% Fold: alpha/alpha toroid Superfamily: Six-hairpin glycosidases Family: Glucoamylase Phyre2 PDB 3qsp chain B Region: 211 - 535 Aligned: 268 Modelled: 292 Confidence: 97.8% Identity: 14% PDB header:hydrolase Chain: B: PDB Molecule:putative uncharacterized protein; PDBTitle: analysis of a new family of widely distributed metal-independent alpha2 mannosidases provides unique insight into the processing of n-linked3 glycans, streptococcus pneumoniae sp_2144 non-productive substrate4 complex with alpha-1,6-mannobiose Phyre2 PDB 2ww1 chain B Region: 147 - 387 Aligned: 171 Modelled: 191 Confidence: 97.8% Identity: 13% PDB header:hydrolase Chain: B: PDB Molecule:putative alpha-1,2-mannosidase; PDBTitle: structure of the family gh92 inverting mannosidase bt39902 from bacteroides thetaiotaomicron vpi-5482 in complex with3 thiomannobioside Phyre2 PDB 1ug9 chain A Region: 148 - 564 Aligned: 325 Modelled: 331 Confidence: 97.7% Identity: 18% PDB header:hydrolase Chain: A: PDB Molecule:glucodextranase; PDBTitle: crystal structure of glucodextranase from arthrobacter globiformis i42 Phyre2 PDB 2eac chain B Region: 155 - 529 Aligned: 287 Modelled: 299 Confidence: 97.7% Identity: 19% PDB header:hydrolase Chain: B: PDB Molecule:alpha-fucosidase; PDBTitle: crystal structure of 1,2-a-l-fucosidase from2 bifidobacterium bifidum in complex with3 deoxyfuconojirimycin Phyre2 PDB 2p0v chain A domain 1 Region: 173 - 532 Aligned: 277 Modelled: 296 Confidence: 97.6% Identity: 15% Fold: alpha/alpha toroid Superfamily: Six-hairpin glycosidases Family: CPF0428-like Phyre2 1 c2jg0A_ 2 d2jg0a1 3 c3c67B_ 4 c2z07A_ 5 c2okxB_ 6 c1v7wA_ 7 d1v7wa1 8 c3cihA_ 9 c2cqtA_ 10 d1lf6a1 11 c1lf6A_ 12 d1ulva1 13 d2fbaa1 14 c2vn4A_ 15 d1gaia_ 16 c3qspB_ 17 c2ww1B_ 18 c1ug9A_ 19 c2eacB_ 20 d2p0va1 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2jg0A_ 100.0 99 PDB header:hydrolase Chain: A: PDB Molecule:periplasmic trehalase; PDBTitle: family 37 trehalase from escherichia coli in complex with 1-2 thiatrehazolin 2 d2jg0a1 100.0 99 Fold:alpha/alpha toroid Superfamily:Six-hairpin glycosidases Family:Trehalase-like 3 c3c67B_ 100.0 17 PDB header:hydrolase Chain: B: PDB Molecule:uncharacterized protein ygjk; PDBTitle: escherichia coli k12 ygjk in a complexed with glucose 4 c2z07A_ 100.0 21 PDB header:hydrolase Chain: A: PDB Molecule:putative uncharacterized protein ttha0978; PDBTitle: crystal structure of uncharacterized conserved protein from2 thermus thermophilus hb8 5 c2okxB_ 99.9 17 PDB header:hydrolase Chain: B: PDB Molecule:rhamnosidase b; PDBTitle: crystal structure of gh78 family rhamnosidase of bacillus sp. gl1 at2 1.9 a 6 c1v7wA_ 99.9 17 PDB header:transferase Chain: A: PDB Molecule:chitobiose phosphorylase; PDBTitle: crystal structure of vibrio proteolyticus chitobiose phosphorylase in2 complex with glcnac 7 d1v7wa1 99.9 17 Fold:alpha/alpha toroid Superfamily:Six-hairpin glycosidases Family:Glycosyltransferase family 36 C-terminal domain 8 c3cihA_ 99.9 13 PDB header:hydrolase Chain: A: PDB Molecule:putative alpha-rhamnosidase; PDBTitle: crystal structure of a putative alpha-rhamnosidase from2 bacteroides thetaiotaomicron 9 c2cqtA_ 99.8 14 PDB header:transferase Chain: A: PDB Molecule:cellobiose phosphorylase; PDBTitle: crystal structure of cellvibrio gilvus cellobiose phosphorylase2 crystallized from sodium/potassium phosphate 10 d1lf6a1 99.8 12 Fold:alpha/alpha toroid Superfamily:Six-hairpin glycosidases Family:Bacterial glucoamylase C-terminal domain-like 11 c1lf6A_ 99.4 14 PDB header:hydrolase Chain: A: PDB Molecule:glucoamylase; PDBTitle: crystal structure of bacterial glucoamylase 12 d1ulva1 99.3 15 Fold:alpha/alpha toroid Superfamily:Six-hairpin glycosidases Family:Bacterial glucoamylase C-terminal domain-like 13 d2fbaa1 98.5 18 Fold:alpha/alpha toroid Superfamily:Six-hairpin glycosidases Family:Glucoamylase 14 c2vn4A_ 98.1 17 PDB header:hydrolase Chain: A: PDB Molecule:glucoamylase; PDBTitle: glycoside hydrolase family 15 glucoamylase from hypocrea2 jecorina 15 d1gaia_ 98.0 20 Fold:alpha/alpha toroid Superfamily:Six-hairpin glycosidases Family:Glucoamylase 16 c3qspB_ 97.8 14 PDB header:hydrolase Chain: B: PDB Molecule:putative uncharacterized protein; PDBTitle: analysis of a new family of widely distributed metal-independent alpha2 mannosidases provides unique insight into the processing of n-linked3 glycans, streptococcus pneumoniae sp_2144 non-productive substrate4 complex with alpha-1,6-mannobiose 17 c2ww1B_ 97.8 13 PDB header:hydrolase Chain: B: PDB Molecule:putative alpha-1,2-mannosidase; PDBTitle: structure of the family gh92 inverting mannosidase bt39902 from bacteroides thetaiotaomicron vpi-5482 in complex with3 thiomannobioside 18 c1ug9A_ 97.7 18 PDB header:hydrolase Chain: A: PDB Molecule:glucodextranase; PDBTitle: crystal structure of glucodextranase from arthrobacter globiformis i42 19 c2eacB_ 97.7 19 PDB header:hydrolase Chain: B: PDB Molecule:alpha-fucosidase; PDBTitle: crystal structure of 1,2-a-l-fucosidase from2 bifidobacterium bifidum in complex with3 deoxyfuconojirimycin 20 d2p0va1 97.6 15 Fold:alpha/alpha toroid Superfamily:Six-hairpin glycosidases Family:CPF0428-like 21 c2p0vA_ not modelled 97.6 15 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein bt3781; PDBTitle: crystal structure of bt3781 protein from bacteroides2 thetaiotaomicron, northeast structural genomics target3 btr58 22 c2rdyB_ not modelled 97.5 14 PDB header:hydrolase Chain: B: PDB Molecule:bh0842 protein; PDBTitle: crystal structure of a putative glycoside hydrolase family2 protein from bacillus halodurans 23 d2nvpa1 not modelled 97.5 15 Fold:alpha/alpha toroid Superfamily:Six-hairpin glycosidases Family:CPF0428-like 24 d1h54a1 not modelled 97.4 12 Fold:alpha/alpha toroid Superfamily:Six-hairpin glycosidases Family:Glycosyltransferase family 36 C-terminal domain 25 c2wvyA_ not modelled 97.1 16 PDB header:hydrolase Chain: A: PDB Molecule:alpha-1,2-mannosidase; PDBTitle: structure of the family gh92 inverting mannosidase bt21992 from bacteroides thetaiotaomicron vpi-5482 26 c1h54B_ not modelled 94.7 16 PDB header:hydrolase Chain: B: PDB Molecule:maltose phosphorylase; PDBTitle: maltose phosphorylase from lactobacillus brevis 27 c3gt5A_ not modelled 89.0 11 PDB header:isomerase Chain: A: PDB Molecule:n-acetylglucosamine 2-epimerase; PDBTitle: crystal structure of an n-acetylglucosamine 2-epimerase family protein2 from xylella fastidiosa 28 c2zzrA_ not modelled 77.8 13 PDB header:hydrolase Chain: A: PDB Molecule:unsaturated glucuronyl hydrolase; PDBTitle: crystal structure of unsaturated glucuronyl hydrolase from2 streptcoccus agalactiae 29 d2afaa1 not modelled 76.4 11 Fold:alpha/alpha toroid Superfamily:Six-hairpin glycosidases Family:N-acylglucosamine (NAG) epimerase 30 c3k7xA_ not modelled 72.5 18 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:lin0763 protein; PDBTitle: crystal structure of the lin0763 protein from listeria2 innocua. northeast structural genomics consortium target3 lkr23. 31 c2gz6B_ not modelled 68.5 11 PDB header:isomerase Chain: B: PDB Molecule:n-acetyl-d-glucosamine 2-epimerase; PDBTitle: crystal structure of anabaena sp. ch1 n-acetyl-d-glucosamine 2-2 epimerase at 2.0 a 32 c3bhwA_ not modelled 66.5 11 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of an uncharacterized protein from magnetospirillum2 magneticum 33 c3ax1A_ not modelled 53.7 18 PDB header:protein binding Chain: A: PDB Molecule:serrate rna effector molecule; PDBTitle: molecular insights into mirna processing by arabidopsis serrate 34 c3racA_ not modelled 52.7 21 PDB header:ligase Chain: A: PDB Molecule:histidine-trna ligase; PDBTitle: crystal strucutre of histidine--trna ligase subunit from2 alicyclobacillus acidocaldarius subsp. acidocaldarius dsm 446. 35 c2idxA_ not modelled 51.1 18 PDB header:transferase Chain: A: PDB Molecule:cob(i)yrinic acid a,c-diamide PDBTitle: structure of human atp:cobalamin adenosyltransferase bound2 to atp. 36 c3pg8B_ not modelled 44.5 18 PDB header:transferase Chain: B: PDB Molecule:phospho-2-dehydro-3-deoxyheptonate aldolase; PDBTitle: truncated form of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase2 from thermotoga maritima 37 d1iwpa_ not modelled 40.2 18 Fold:TIM beta/alpha-barrel Superfamily:Cobalamin (vitamin B12)-dependent enzymes Family:Diol dehydratase, alpha subunit 38 d1nzpa_ not modelled 37.7 24 Fold:SAM domain-like Superfamily:DNA polymerase beta, N-terminal domain-like Family:DNA polymerase beta, N-terminal domain-like 39 c2q07A_ not modelled 36.8 33 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein af0587; PDBTitle: crystal structure of af0587, a protein of unknown function 40 d1q79a3 not modelled 33.3 10 Fold:Ferredoxin-like Superfamily:PAP/Archaeal CCA-adding enzyme, C-terminal domain Family:Poly(A) polymerase, PAP, C-terminal domain 41 d1wu7a2 not modelled 31.2 35 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 42 d1dq3a2 not modelled 30.6 19 Fold:dsRBD-like Superfamily:YcfA/nrd intein domain Family:PI-Pfui intein middle domain 43 c1wy1B_ not modelled 29.7 40 PDB header:transferase Chain: B: PDB Molecule:hypothetical protein ph0671; PDBTitle: crystal structure of the ph0671 protein from pyrococcus horikoshii ot3 44 d1usya_ not modelled 28.3 28 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 45 d1uj8a1 not modelled 25.9 4 Fold:Another 3-helical bundle Superfamily:IscX-like Family:IscX-like 46 c2cseW_ not modelled 25.4 21 PDB header:virus Chain: W: PDB Molecule:major core protein lambda 1; PDBTitle: features of reovirus outer-capsid protein mu1 revealed by2 electron and image reconstruction of the virion at 7.0-a3 resolution 47 c3k1qB_ not modelled 25.2 29 PDB header:virus Chain: B: PDB Molecule:vp3a, the building block protein of inner shell; PDBTitle: backbone model of an aquareovirus virion by cryo-electron2 microscopy and bioinformatics 48 d1z7ma1 not modelled 24.9 26 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 49 c3k1qC_ not modelled 24.2 29 PDB header:virus Chain: C: PDB Molecule:vp3b, the building block protein of inner shell; PDBTitle: backbone model of an aquareovirus virion by cryo-electron2 microscopy and bioinformatics 50 c1wvtA_ not modelled 24.1 36 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein st2180; PDBTitle: crystal structure of uncharacterized protein st2180 from sulfolobus2 tokodaii 51 d1vr6a1 not modelled 23.1 18 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I DAHP synthetase 52 d2hfha_ not modelled 22.9 22 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Forkhead DNA-binding domain 53 d3bpya1 not modelled 20.8 13 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Forkhead DNA-binding domain 54 c3lhrA_ not modelled 20.3 14 PDB header:transcription regulator Chain: A: PDB Molecule:zinc finger protein 24; PDBTitle: crystal structure of the scan domain from human znf24 55 c1z7nB_ not modelled 20.3 21 PDB header:transferase Chain: B: PDB Molecule:atp phosphoribosyltransferase regulatory subunit; PDBTitle: atp phosphoribosyl transferase (hiszg atp-prtase) from2 lactococcus lactis with bound prpp substrate 56 d1xg7a_ not modelled 19.8 8 Fold:DNA-glycosylase Superfamily:DNA-glycosylase Family:AgoG-like 57 d1jmsa1 not modelled 18.9 14 Fold:SAM domain-like Superfamily:DNA polymerase beta, N-terminal domain-like Family:DNA polymerase beta, N-terminal domain-like 58 d2bcqa1 not modelled 18.6 29 Fold:SAM domain-like Superfamily:DNA polymerase beta, N-terminal domain-like Family:DNA polymerase beta, N-terminal domain-like 59 c3t4cD_ not modelled 18.3 13 PDB header:transferase Chain: D: PDB Molecule:2-dehydro-3-deoxyphosphooctonate aldolase 1; PDBTitle: crystal structure of 2-dehydro-3-deoxyphosphooctonate aldolase from2 burkholderia ambifaria 60 d2fmpa1 not modelled 17.4 27 Fold:SAM domain-like Superfamily:DNA polymerase beta, N-terminal domain-like Family:DNA polymerase beta, N-terminal domain-like 61 c3od1A_ not modelled 16.5 22 PDB header:transferase Chain: A: PDB Molecule:atp phosphoribosyltransferase regulatory subunit; PDBTitle: the crystal structure of an atp phosphoribosyltransferase regulatory2 subunit/histidyl-trna synthetase from bacillus halodurans c 62 d1nc5a_ not modelled 16.2 10 Fold:alpha/alpha toroid Superfamily:Six-hairpin glycosidases Family:Hypothetical protein YteR 63 d1z3xa1 not modelled 15.2 14 Fold:alpha-alpha superhelix Superfamily:ARM repeat Family:GUN4-associated domain 64 c2q17C_ not modelled 15.0 42 PDB header:unknown function Chain: C: PDB Molecule:formylglycine generating enzyme; PDBTitle: formylglycine generating enzyme from streptomyces coelicolor 65 d1aina_ not modelled 14.9 9 Fold:Annexin Superfamily:Annexin Family:Annexin 66 d1rutx4 not modelled 14.8 71 Fold:Glucocorticoid receptor-like (DNA-binding domain) Superfamily:Glucocorticoid receptor-like (DNA-binding domain) Family:LIM domain 67 c2lmdA_ not modelled 14.4 83 PDB header:transcription Chain: A: PDB Molecule:prospero homeobox protein 1; PDBTitle: minimal constraints solution nmr structure of prospero homeobox2 protein 1 from homo sapiens, northeast structural genomics consortium3 target hr4660b 68 c3c1lB_ not modelled 14.3 19 PDB header:oxidoreductase Chain: B: PDB Molecule:putative antioxidant defense protein mlr4105; PDBTitle: crystal structure of an antioxidant defense protein (mlr4105) from2 mesorhizobium loti maff303099 at 2.00 a resolution 69 c2ah6B_ not modelled 14.1 42 PDB header:transferase Chain: B: PDB Molecule:bh1595, unknown conserved protein; PDBTitle: crystal structure of a putative cobalamin adenosyltransferase (bh1595)2 from bacillus halodurans c-125 at 1.60 a resolution 70 c1wozA_ not modelled 13.8 33 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:177aa long conserved hypothetical protein (st1454); PDBTitle: crystal structure of uncharacterized protein st1454 from sulfolobus2 tokodaii 71 d1rtyb_ not modelled 13.8 33 Fold:Ferritin-like Superfamily:Cobalamin adenosyltransferase-like Family:Cobalamin adenosyltransferase 72 c2yukA_ not modelled 13.6 22 PDB header:transferase Chain: A: PDB Molecule:myeloid/lymphoid or mixed-lineage leukemia PDBTitle: solution structure of the hmg box of human myeloid/lymphoid2 or mixed-lineage leukemia protein 3 homolog 73 c2c1lA_ not modelled 13.3 43 PDB header:hydrolase Chain: A: PDB Molecule:restriction endonuclease; PDBTitle: structure of the bfii restriction endonuclease 74 c2nt8A_ not modelled 13.3 33 PDB header:transferase Chain: A: PDB Molecule:cobalamin adenosyltransferase; PDBTitle: atp bound at the active site of a pduo type atp:co(i)rrinoid2 adenosyltransferase from lactobacillus reuteri 75 c3llbA_ not modelled 12.9 21 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: the crystal structure of the protein pa3983 with unknown2 function from pseudomonas aeruginosa pao1 76 c3co7C_ not modelled 12.8 26 PDB header:transcription/dna Chain: C: PDB Molecule:forkhead box protein o1; PDBTitle: crystal structure of foxo1 dbd bound to dbe2 dna 77 c2r2vB_ not modelled 12.6 27 PDB header:de novo protein Chain: B: PDB Molecule:gcn4 leucine zipper; PDBTitle: sequence determinants of the topology of the lac repressor2 tetrameric coiled coil 78 d2a21a1 not modelled 12.4 15 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I DAHP synthetase 79 d1rtya_ not modelled 12.4 33 Fold:Ferritin-like Superfamily:Cobalamin adenosyltransferase-like Family:Cobalamin adenosyltransferase 80 c3ha4C_ not modelled 12.3 19 PDB header:unknown function Chain: C: PDB Molecule:mix1; PDBTitle: crystal structure of the type one membrane protein mix1 from2 leishmania 81 d1noga_ not modelled 12.3 50 Fold:Ferritin-like Superfamily:Cobalamin adenosyltransferase-like Family:Cobalamin adenosyltransferase 82 c1nogA_ not modelled 12.3 50 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:conserved hypothetical protein ta0546; PDBTitle: crystal structure of conserved protein 0546 from thermoplasma2 acidophilum 83 c3lzzB_ not modelled 12.0 78 PDB header:unknown function Chain: B: PDB Molecule:putative uncharacterized protein; PDBTitle: crystal structures of cupin superfamily bbduf985 from branchiostoma2 belcheri tsingtauense in apo and gdp-bound forms 84 d2zdra2 not modelled 11.9 17 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:NeuB-like 85 d1fp3a_ not modelled 11.9 13 Fold:alpha/alpha toroid Superfamily:Six-hairpin glycosidases Family:N-acylglucosamine (NAG) epimerase 86 c3ke4B_ not modelled 11.8 42 PDB header:transferase Chain: B: PDB Molecule:hypothetical cytosolic protein; PDBTitle: crystal structure of a pduo-type atp:cob(i)alamin adenosyltransferase2 from bacillus cereus 87 c3sz8D_ not modelled 11.7 7 PDB header:transferase Chain: D: PDB Molecule:2-dehydro-3-deoxyphosphooctonate aldolase 2; PDBTitle: crystal structure of 2-dehydro-3-deoxyphosphooctonate aldolase from2 burkholderia pseudomallei 88 c2zhzC_ not modelled 11.3 43 PDB header:transferase Chain: C: PDB Molecule:atp:cob(i)alamin adenosyltransferase, putative; PDBTitle: crystal structure of a pduo-type atp:cobalamin adenosyltransferase2 from burkholderia thailandensis 89 c3ci1A_ not modelled 11.0 33 PDB header:transferase Chain: A: PDB Molecule:cobalamin adenosyltransferase pduo-like protein; PDBTitle: structure of the pduo-type atp:co(i)rrinoid2 adenosyltransferase from lactobacillus reuteri complexed3 with four-coordinate cob(ii)alamin and atp 90 c1xrsB_ not modelled 10.9 15 PDB header:isomerase Chain: B: PDB Molecule:d-lysine 5,6-aminomutase beta subunit; PDBTitle: crystal structure of lysine 5,6-aminomutase in complex with plp,2 cobalamin, and 5'-deoxyadenosine 91 c2g2dA_ not modelled 10.6 50 PDB header:transferase Chain: A: PDB Molecule:atp:cobalamin adenosyltransferase; PDBTitle: crystal structure of a putative pduo-type atp:cobalamin2 adenosyltransferase from mycobacterium tuberculosis 92 d2itka1 not modelled 10.5 25 Fold:WW domain-like Superfamily:WW domain Family:WW domain 93 c2xtdB_ not modelled 10.4 16 PDB header:transcription Chain: B: PDB Molecule:tbl1 f-box-like/wd repeat-containing protein tbl1x; PDBTitle: structure of the tbl1 tetramerisation domain 94 c3iqtA_ not modelled 10.3 15 PDB header:transferase Chain: A: PDB Molecule:signal transduction histidine-protein kinase bara; PDBTitle: structure of the hpt domain of sensor protein bara from escherichia2 coli cft073. 95 d1fs1b1 not modelled 10.2 22 Fold:Skp1 dimerisation domain-like Superfamily:Skp1 dimerisation domain-like Family:Skp1 dimerisation domain-like 96 c1xuzA_ not modelled 10.2 15 PDB header:biosynthetic protein Chain: A: PDB Molecule:polysialic acid capsule biosynthesis protein siac; PDBTitle: crystal structure analysis of sialic acid synthase (neub)from2 neisseria meningitidis, bound to mn2+, phosphoenolpyruvate, and n-3 acetyl mannosaminitol 97 c2bcuA_ not modelled 10.0 28 PDB header:transferase, lyase/dna Chain: A: PDB Molecule:dna polymerase lambda; PDBTitle: dna polymerase lambda in complex with a dna duplex2 containing an unpaired damp and a t:t mismatch 98 d1o65a_ not modelled 10.0 6 Fold:PK beta-barrel domain-like Superfamily:PK beta-barrel domain-like Family:MOSC (MOCO sulphurase C-terminal) domain 99 c2xteH_ not modelled 9.8 16 PDB header:transcription Chain: H: PDB Molecule:f-box-like/wd repeat-containing protein tbl1x; PDBTitle: structure of the tbl1 tetramerisation domain

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0