Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionQ9TYT3
DateSat Apr 13 13:01:24 BST 2013
Unique Job ID2b16cb7caa7c6c32

Summary 

Top model
Image coloured by rainbow N → C terminus
Model dimensions (Å):X:52.228 Y:43.781 Z:37.032
Model (left) based on template d1oy2a_
Top template information
Fold:PH domain-like barrel
Superfamily:PH domain-like
Family:Phosphotyrosine-binding domain (PTB)
Confidence and coverage
Confidence:100.0% Coverage: 50%
159 residues ( 50% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
282 residues ( 89%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MLNVEPSFAEELRSSGVSLSATYLGSVPVVESINVMVSEMRVQVVSECIQHVAATVGVTA
Secondary structure 
SS confidence 
Disorder  ?????
????????
???
Disorder confidence 
 
   .........70.........80.........90.........100.........110.........120
Sequence  AREINPVVSRVIGEVKKENFPVDINISSKMIKIIKQSRLIQRHPFSFFSFGAQGQKGTDT
Secondary structure 
SS confidence 
Disorder  ??????
?
???
???????
??
??
?
?
??
Disorder confidence 
 
   .........130.........140.........150.........160.........170.........180
Sequence  ELMFGYIAKNKDGTDRRCHVVFIEDVHKLIDVLTTAINVNTFDAQANASTSNDGFTVPAP
Secondary structure 
SS confidence 
Disorder 
????????
??????
??
??????????????????????
Disorder confidence 
 
   .........190.........200.........210.........220.........230.........240
Sequence  PMRHRSSLHRQSFVSNCRAPTVTEDVVGKVWYHGNLSREDAQALLKTEGDFLVRQSDHTP
Secondary structure 
SS confidence 
Disorder  ??????????????????????
Disorder confidence 
 
   .........250.........260.........270.........280.........290.........300
Sequence  GKYVLSGRTAENEHKHLILLDNHNRVRTRDRTFSNISELIDYHVNNGMAVRSEGRDRETS
Secondary structure 
SS confidence 
Disorder 
?
??????
??
Disorder confidence 
 
   .........310......
Sequence  LNLIRPVPCPGSDDIE
Secondary structure 
SS confidence 
Disorder 
???????
Disorder confidence 
 

Confidence Key
High(9)                    Low (0)
?Disordered ( 37%)
Alpha helix ( 28%)
Beta strand ( 15%)

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1oy2 chain A

3D model

Region: 7 - 171
Aligned: 159
Modelled: 165
Confidence: 100.0%
Identity: 21%
Fold: PH domain-like barrel
Superfamily: PH domain-like
Family: Phosphotyrosine-binding domain (PTB)

Phyre2

PDB 3suz chain A

3D model

Region: 8 - 174
Aligned: 153
Modelled: 167
Confidence: 100.0%
Identity: 22%
PDB header:protein binding
Chain: A: PDB Molecule:amyloid beta a4 precursor protein-binding family a member
PDBTitle: crystal structure of rat mint2 ppc

Phyre2

PDB 3sv1 chain C

3D model

Region: 8 - 163
Aligned: 137
Modelled: 156
Confidence: 100.0%
Identity: 23%
PDB header:protein binding
Chain: C: PDB Molecule:amyloid beta a4 precursor protein-binding family a member
PDBTitle: crystal structure of app peptide bound rat mint2 parm

Phyre2

PDB 1p3r chain A

3D model

Region: 1 - 169
Aligned: 143
Modelled: 154
Confidence: 100.0%
Identity: 17%
Fold: PH domain-like barrel
Superfamily: PH domain-like
Family: Phosphotyrosine-binding domain (PTB)

Phyre2

PDB 3d8d chain A

3D model

Region: 15 - 163
Aligned: 134
Modelled: 140
Confidence: 100.0%
Identity: 17%
PDB header:protein binding
Chain: A: PDB Molecule:amyloid beta a4 precursor protein-binding family b member
PDBTitle: crystal structure of the human fe65-ptb1 domain

Phyre2

PDB 2m38 chain A

3D model

Region: 10 - 167
Aligned: 133
Modelled: 145
Confidence: 100.0%
Identity: 22%
PDB header:peptide binding protein
Chain: A: PDB Molecule:ankyrin repeat and sterile alpha motif domain-containing
PDBTitle: ptb domain of aida1

Phyre2

PDB 1wj1 chain A

3D model

Region: 7 - 177
Aligned: 138
Modelled: 151
Confidence: 100.0%
Identity: 22%
Fold: PH domain-like barrel
Superfamily: PH domain-like
Family: Phosphotyrosine-binding domain (PTB)

Phyre2

PDB 1ntv chain A

3D model

Region: 4 - 172
Aligned: 143
Modelled: 154
Confidence: 100.0%
Identity: 16%
Fold: PH domain-like barrel
Superfamily: PH domain-like
Family: Phosphotyrosine-binding domain (PTB)

Phyre2

PDB 1aqc chain A

3D model

Region: 10 - 164
Aligned: 125
Modelled: 141
Confidence: 100.0%
Identity: 25%
Fold: PH domain-like barrel
Superfamily: PH domain-like
Family: Phosphotyrosine-binding domain (PTB)

Phyre2

PDB 3so6 chain A

3D model

Region: 16 - 172
Aligned: 129
Modelled: 141
Confidence: 100.0%
Identity: 20%
PDB header:protein binding/protein transport
Chain: A: PDB Molecule:ldl receptor adaptor protein;
PDBTitle: crystal structure of the ldl receptor tail in complex with autosomal2 recessive hypercholesterolemia ptb domain

Phyre2

PDB 2dkq chain A domain 1

3D model

Region: 6 - 158
Aligned: 128
Modelled: 135
Confidence: 100.0%
Identity: 25%
Fold: PH domain-like barrel
Superfamily: PH domain-like
Family: Phosphotyrosine-binding domain (PTB)

Phyre2

PDB 2ysz chain A

3D model

Region: 6 - 186
Aligned: 143
Modelled: 163
Confidence: 100.0%
Identity: 18%
PDB header:protein binding
Chain: A: PDB Molecule:amyloid beta a4 precursor protein-binding family
PDBTitle: solution structure of the chimera of the c-terminal pid2 domain of fe65l and the c-terminal tail peptide of app

Phyre2

PDB 2ela chain B

3D model

Region: 18 - 172
Aligned: 129
Modelled: 137
Confidence: 99.9%
Identity: 16%
PDB header:cell cycle
Chain: B: PDB Molecule:adapter protein containing ph domain, ptb domain
PDBTitle: crystal structure of the ptb domain of human appl1

Phyre2

PDB 2gsb chain A

3D model

Region: 195 - 313
Aligned: 110
Modelled: 119
Confidence: 99.9%
Identity: 34%
PDB header:signaling protein
Chain: A: PDB Molecule:ras gtpase-activating protein 1;
PDBTitle: solution structure of the second sh2 domain of human ras2 gtpase-activating protein 1

Phyre2

PDB 2dcr chain A

3D model

Region: 194 - 312
Aligned: 112
Modelled: 119
Confidence: 99.9%
Identity: 29%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fes/fps;
PDBTitle: fully automated solution structure determination of the fes2 sh2 domain

Phyre2

PDB 2hdx chain B

3D model

Region: 204 - 308
Aligned: 99
Modelled: 105
Confidence: 99.9%
Identity: 28%
PDB header:signaling protein
Chain: B: PDB Molecule:sh2-b ph domain containing signaling mediator 1
PDBTitle: crystal structure of the src homology-2 domain of sh2-b in2 complex with jak2 ptyr813 phosphopeptide

Phyre2

PDB 3dxe chain C

3D model

Region: 13 - 174
Aligned: 128
Modelled: 144
Confidence: 99.9%
Identity: 19%
PDB header:protein binding
Chain: C: PDB Molecule:amyloid beta a4 protein-binding family b member
PDBTitle: crystal structure of the intracellular domain of human app2 (t668a mutant) in complex with fe65-ptb2

Phyre2

PDB 2yt1 chain A

3D model

Region: 14 - 156
Aligned: 113
Modelled: 125
Confidence: 99.9%
Identity: 19%
PDB header:protein binding
Chain: A: PDB Molecule:amyloid beta a4 protein and amyloid beta a4
PDBTitle: solution structure of the chimera of the c-terminal tail2 peptide of app and the c-terminal pid domain of fe65l

Phyre2

PDB 2kk6 chain A

3D model

Region: 200 - 310
Aligned: 105
Modelled: 111
Confidence: 99.9%
Identity: 36%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fer;
PDBTitle: solution structure of sh2 domain of proto-oncogene tyrosine-2 protein kinase fer from homo sapiens, northeast structural3 genomics consortium (nesg) target hr3461d

Phyre2

PDB 1ddm chain A

3D model

Region: 9 - 161
Aligned: 123
Modelled: 130
Confidence: 99.9%
Identity: 28%
Fold: PH domain-like barrel
Superfamily: PH domain-like
Family: Phosphotyrosine-binding domain (PTB)

Phyre2

PDB 1mil chain A

3D model

Region: 205 - 309
Aligned: 100
Modelled: 100
Confidence: 99.9%
Identity: 47%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2
1
d1oy2a_
2
c3suzA_
3
c3sv1C_
4
d1p3ra_
5
c3d8dA_
6
c2m38A_
7
d1wj1a_
8
d1ntva_
9
d1aqca_
10
c3so6A_
11
d2dkqa1
12
c2yszA_
13
c2elaB_
14
c2gsbA_
15
c2dcrA_
16
c2hdxB_
17
c3dxeC_
18
c2yt1A_
19
c2kk6A_
20
d1ddma_
21
22
d1mila_
23
24
25
26
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28
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1d1oy2a_
100.0 21 Fold:PH domain-like barrel
Superfamily:PH domain-like
Family:Phosphotyrosine-binding domain (PTB)
2c3suzA_
100.0 22 PDB header:protein binding
Chain: A: PDB Molecule:amyloid beta a4 precursor protein-binding family a member
PDBTitle: crystal structure of rat mint2 ppc
3c3sv1C_
100.0 23 PDB header:protein binding
Chain: C: PDB Molecule:amyloid beta a4 precursor protein-binding family a member
PDBTitle: crystal structure of app peptide bound rat mint2 parm
4d1p3ra_
100.0 17 Fold:PH domain-like barrel
Superfamily:PH domain-like
Family:Phosphotyrosine-binding domain (PTB)
5c3d8dA_
100.0 17 PDB header:protein binding
Chain: A: PDB Molecule:amyloid beta a4 precursor protein-binding family b member
PDBTitle: crystal structure of the human fe65-ptb1 domain
6c2m38A_
100.0 22 PDB header:peptide binding protein
Chain: A: PDB Molecule:ankyrin repeat and sterile alpha motif domain-containing
PDBTitle: ptb domain of aida1
7d1wj1a_
100.0 22 Fold:PH domain-like barrel
Superfamily:PH domain-like
Family:Phosphotyrosine-binding domain (PTB)
8d1ntva_
100.0 16 Fold:PH domain-like barrel
Superfamily:PH domain-like
Family:Phosphotyrosine-binding domain (PTB)
9d1aqca_
100.0 25 Fold:PH domain-like barrel
Superfamily:PH domain-like
Family:Phosphotyrosine-binding domain (PTB)
10c3so6A_
100.0 20 PDB header:protein binding/protein transport
Chain: A: PDB Molecule:ldl receptor adaptor protein;
PDBTitle: crystal structure of the ldl receptor tail in complex with autosomal2 recessive hypercholesterolemia ptb domain
11d2dkqa1
100.0 25 Fold:PH domain-like barrel
Superfamily:PH domain-like
Family:Phosphotyrosine-binding domain (PTB)
12c2yszA_
100.0 18 PDB header:protein binding
Chain: A: PDB Molecule:amyloid beta a4 precursor protein-binding family
PDBTitle: solution structure of the chimera of the c-terminal pid2 domain of fe65l and the c-terminal tail peptide of app
13c2elaB_
99.9 16 PDB header:cell cycle
Chain: B: PDB Molecule:adapter protein containing ph domain, ptb domain
PDBTitle: crystal structure of the ptb domain of human appl1
14c2gsbA_
99.9 34 PDB header:signaling protein
Chain: A: PDB Molecule:ras gtpase-activating protein 1;
PDBTitle: solution structure of the second sh2 domain of human ras2 gtpase-activating protein 1
15c2dcrA_
99.9 29 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fes/fps;
PDBTitle: fully automated solution structure determination of the fes2 sh2 domain
16c2hdxB_
99.9 28 PDB header:signaling protein
Chain: B: PDB Molecule:sh2-b ph domain containing signaling mediator 1
PDBTitle: crystal structure of the src homology-2 domain of sh2-b in2 complex with jak2 ptyr813 phosphopeptide
17c3dxeC_
99.9 19 PDB header:protein binding
Chain: C: PDB Molecule:amyloid beta a4 protein-binding family b member
PDBTitle: crystal structure of the intracellular domain of human app2 (t668a mutant) in complex with fe65-ptb2
18c2yt1A_
99.9 19 PDB header:protein binding
Chain: A: PDB Molecule:amyloid beta a4 protein and amyloid beta a4
PDBTitle: solution structure of the chimera of the c-terminal tail2 peptide of app and the c-terminal pid domain of fe65l
19c2kk6A_
99.9 36 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fer;
PDBTitle: solution structure of sh2 domain of proto-oncogene tyrosine-2 protein kinase fer from homo sapiens, northeast structural3 genomics consortium (nesg) target hr3461d
20d1ddma_
99.9 28 Fold:PH domain-like barrel
Superfamily:PH domain-like
Family:Phosphotyrosine-binding domain (PTB)
21c2eo6A_
not modelled 99.9 22 PDB header:signaling protein
Chain: A: PDB Molecule:b-cell linker protein;
PDBTitle: solution structure of the sh2 domain from mouse b-cell2 linker protein blnk
22d1mila_
99.9 47 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
23c2dlzA_
not modelled 99.9 19 PDB header:signaling protein
Chain: A: PDB Molecule:protein vav-2;
PDBTitle: solution structure of the sh2 domain of human protein vav-2
24c2eo3A_
not modelled 99.9 28 PDB header:signaling protein
Chain: A: PDB Molecule:crk-like protein;
PDBTitle: solution structure of the sh2 domain from human crk-like2 protein
25c2dyqA_
not modelled 99.9 22 PDB header:protein binding
Chain: A: PDB Molecule:amyloid beta a4 precursor protein-binding family b member
PDBTitle: crystal structure of the c-terminal phophotyrosine interaction domain2 of human apbb3
26d2cy5a1
not modelled 99.9 11 Fold:PH domain-like barrel
Superfamily:PH domain-like
Family:Phosphotyrosine-binding domain (PTB)
27c2dlyA_
not modelled 99.9 22 PDB header:transferase
Chain: A: PDB Molecule:fyn-related kinase;
PDBTitle: solution structure of the sh2 domain of murine fyn-related2 kinase
28d3c7ia1
not modelled 99.9 27 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
29c2lqnA_
not modelled 99.9 28 PDB header:signaling protein
Chain: A: PDB Molecule:crk-like protein;
PDBTitle: solution structure of crkl
30d2oq1a1
not modelled 99.9 24 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
31c2b3oA_
not modelled 99.9 29 PDB header:hydrolase
Chain: A: PDB Molecule:tyrosine-protein phosphatase, non-receptor type
PDBTitle: crystal structure of human tyrosine phosphatase shp-1
32d1wgua_
not modelled 99.9 22 Fold:PH domain-like barrel
Superfamily:PH domain-like
Family:Phosphotyrosine-binding domain (PTB)
33d2shpa2
not modelled 99.9 25 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
34c2oq1A_
not modelled 99.9 24 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase zap-70;
PDBTitle: tandem sh2 domains of zap-70 with 19-mer zeta1 peptide
35d1fhsa_
not modelled 99.9 26 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
36d1wvha1
not modelled 99.9 20 Fold:PH domain-like barrel
Superfamily:PH domain-like
Family:Phosphotyrosine-binding domain (PTB)
37c1ka6A_
not modelled 99.9 27 PDB header:immune system
Chain: A: PDB Molecule:sh2 domain protein 1a;
PDBTitle: sap/sh2d1a bound to peptide n-py
38c3hizB_
not modelled 99.9 28 PDB header:transferase/oncoprotein
Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit
PDBTitle: crystal structure of p110alpha h1047r mutant in complex with2 nish2 of p85alpha
39c1x6cA_
not modelled 99.9 27 PDB header:signaling protein
Chain: A: PDB Molecule:tyrosine-protein phosphatase, non-receptor type
PDBTitle: solution structures of the sh2 domain of human protein-2 tyrosine phosphatase shp-1
40c2eobA_
not modelled 99.9 26 PDB header:hydrolase
Chain: A: PDB Molecule:1-phosphatidylinositol-4,5-bisphosphate
PDBTitle: solution structure of the second sh2 domain from rat plc2 gamma-2
41c2crhA_
not modelled 99.9 22 PDB header:signaling protein
Chain: A: PDB Molecule:vav proto-oncogene;
PDBTitle: solution structure of the sh2 domain of human proto-2 oncogene protein vav1
42d1rjaa_
not modelled 99.9 28 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
43d1opka2
not modelled 99.9 28 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
44c2ci8A_
not modelled 99.9 27 PDB header:translation
Chain: A: PDB Molecule:cytoplasmic protein nck1;
PDBTitle: sh2 domain of human nck1 adaptor protein - uncomplexed
45d1blja_
not modelled 99.9 25 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
46c2shpA_
not modelled 99.9 25 PDB header:tyrosine phosphatase
Chain: A: PDB Molecule:shp-2;
PDBTitle: tyrosine phosphatase shp-2
47c2fo0A_
not modelled 99.9 30 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase abl1 (1b isoform);
PDBTitle: organization of the sh3-sh2 unit in active and inactive forms of the2 c-abl tyrosine kinase
48d1a81e1
not modelled 99.9 24 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
49d1a81e2
not modelled 99.9 24 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
50d1d4ta_
not modelled 99.9 25 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
51d2izva2
not modelled 99.9 24 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
52d1jwoa_
not modelled 99.9 25 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
53d1a81a1
not modelled 99.9 27 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
54d1pica_
not modelled 99.9 22 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
55d1ayaa_
not modelled 99.9 24 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
56c3gqiB_
not modelled 99.9 28 PDB header:transferase/transferase inhibitor
Chain: B: PDB Molecule:phospholipase c-gamma-1;
PDBTitle: crystal structure of activated receptor tyrosine kinase in complex2 with substrates
57c2y3aB_
not modelled 99.9 22 PDB header:transferase
Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit beta;
PDBTitle: crystal structure of p110beta in complex with icsh2 of p85beta and2 the drug gdc-0941
58c2ablA_
not modelled 99.9 29 PDB header:transferase
Chain: A: PDB Molecule:abl tyrosine kinase;
PDBTitle: sh3-sh2 domain fragment of human bcr-abl tyrosine kinase
59d2oq1a2
not modelled 99.9 27 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
60d1csya_
not modelled 99.9 24 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
61d1nrva_
not modelled 99.9 23 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
62c2ozoA_
not modelled 99.9 23 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase zap-70;
PDBTitle: autoinhibited intact human zap-70
63c2lctA_
not modelled 99.9 21 PDB header:signaling protein
Chain: A: PDB Molecule:proto-oncogene vav;
PDBTitle: solution structure of the vav1 sh2 domain complexed with a syk-derived2 doubly phosphorylated peptide
64c2ysxA_
not modelled 99.9 29 PDB header:signaling protein
Chain: A: PDB Molecule:signaling inositol polyphosphate phosphatase
PDBTitle: solution structure of the human ship sh2 domain
65d1a81a2
not modelled 99.9 22 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
66d1k9aa2
not modelled 99.9 29 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
67c2ge9A_
not modelled 99.9 28 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase btk;
PDBTitle: solution structures of the sh2 domain of bruton's tyrosine2 kinase
68c2augB_
not modelled 99.9 24 PDB header:signaling protein
Chain: B: PDB Molecule:growth factor receptor-bound protein 14;
PDBTitle: crystal structure of the grb14 sh2 domain
69d1r1qa_
not modelled 99.9 26 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
70c1oplA_
not modelled 99.9 30 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase;
PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase
71c2hmhA_
not modelled 99.9 19 PDB header:cytokine regulator
Chain: A: PDB Molecule:suppressor of cytokine signaling 3;
PDBTitle: crystal structure of socs3 in complex with gp130(ptyr757)2 phosphopeptide.
72d2cs0a1
not modelled 99.9 26 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
73c1k9aB_
not modelled 99.9 28 PDB header:transferase
Chain: B: PDB Molecule:carboxyl-terminal src kinase;
PDBTitle: crystal structure analysis of full-length carboxyl-terminal2 src kinase at 2.5 a resolution
74c4fl2A_
not modelled 99.9 26 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase syk;
PDBTitle: structural and biophysical characterization of the syk activation2 switch
75c3ps5A_
not modelled 99.9 28 PDB header:hydrolase, signaling protein
Chain: A: PDB Molecule:tyrosine-protein phosphatase non-receptor type 6;
PDBTitle: crystal structure of the full-length human protein tyrosine2 phosphatase shp-1
76d1bkla_
not modelled 99.9 29 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
77d2qmsa1
not modelled 99.9 28 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
78d1f2fa_
not modelled 99.9 29 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
79d1jyra_
not modelled 99.9 25 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
80d2eyva1
not modelled 99.9 36 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
81d1lkka_
not modelled 99.9 33 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
82d2fcia1
not modelled 99.9 30 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
83d1i3za_
not modelled 99.9 28 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
84c2vifA_
not modelled 99.9 24 PDB header:signaling protein
Chain: A: PDB Molecule:suppressor of cytokine signalling 6;
PDBTitle: crystal structure of socs6 sh2 domain in complex with a c-kit2 phosphopeptide
85d1fu6a_
not modelled 99.9 28 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
86c1y57A_
not modelled 99.9 22 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor
87d2shpa3
not modelled 99.9 36 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
88d1o48a_
not modelled 99.9 28 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
89c1a81E_
not modelled 99.9 21 PDB header:complex (transferase/peptide)
Chain: E: PDB Molecule:syk kinase;
PDBTitle: crystal structure of the tandem sh2 domain of the syk kinase bound to2 a dually tyrosine-phosphorylated itam
90c2c9wA_
not modelled 99.9 27 PDB header:transcription regulation
Chain: A: PDB Molecule:suppressor of cytokine signaling 2;
PDBTitle: crystal structure of socs-2 in complex with elongin-b and2 elongin-c at 1.9a resolution
91d1qcfa2
not modelled 99.9 27 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
92d1g83a2
not modelled 99.9 29 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
93c1x27F_
not modelled 99.9 31 PDB header:signaling protein
Chain: F: PDB Molecule:proto-oncogene tyrosine-protein kinase lck;
PDBTitle: crystal structure of lck sh2-sh3 with sh2 binding site of2 p130cas
94c2dm0A_
not modelled 99.9 30 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase txk;
PDBTitle: solution structure of the sh2 domain of human tyrosine-2 protein kinase txk
95d1xa6a2
not modelled 99.9 25 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
96c2izvA_
not modelled 99.9 21 PDB header:transcription
Chain: A: PDB Molecule:suppressor of cytokine signaling 4;
PDBTitle: crystal structure of socs-4 in complex with elongin-b and2 elongin-c at 2.55a resolution
97d1qada_
not modelled 99.9 24 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
98c3nhnA_
not modelled 99.9 26 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase hck;
PDBTitle: crystal structure of the src-family kinase hck sh3-sh2-linker2 regulatory region
99c2knoA_
not modelled 99.9 31 PDB header:hydrolase
Chain: A: PDB Molecule:tensin-like c1 domain-containing phosphatase;
PDBTitle: nmr solution structure of sh2 domain of the human tensin like c12 domain containing phosphatase (tenc1)
100d1luia_
not modelled 99.9 35 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
101c2h8hA_
not modelled 99.9 27 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: src kinase in complex with a quinazoline inhibitor
102c2c0iA_
not modelled 99.9 24 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase hck;
PDBTitle: src family kinase hck with bound inhibitor a-420983
103c2ekxA_
not modelled 99.9 30 PDB header:signaling protein
Chain: A: PDB Molecule:cytoplasmic tyrosine-protein kinase bmx;
PDBTitle: solution structure of the human bmx sh2 domain
104d2c9wa2
not modelled 99.9 27 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
105c1rqqC_
not modelled 99.8 26 PDB header:transferase/signaling protein
Chain: C: PDB Molecule:adaptor protein aps;
PDBTitle: crystal structure of the insulin receptor kinase in complex2 with the sh2 domain of aps
106d1rpya_
not modelled 99.8 27 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
107c3mazA_
not modelled 99.8 20 PDB header:signaling protein
Chain: A: PDB Molecule:signal-transducing adaptor protein 1;
PDBTitle: crystal structure of the human brdg1/stap-1 sh2 domain in complex with2 the ntal ptyr136 peptide
108c2el8A_
not modelled 99.8 17 PDB header:signaling protein
Chain: A: PDB Molecule:signal-transducing adaptor protein 2;
PDBTitle: solution structure of the human stap2 sh2 domain
109c3gxxB_
not modelled 99.8 16 PDB header:transcription
Chain: B: PDB Molecule:transcription elongation factor spt6;
PDBTitle: structure of the sh2 domain of the candida glabrata2 transcription elongation factor spt6, crystal form b
110c1g83A_
not modelled 99.8 29 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fyn;
PDBTitle: crystal structure of fyn sh3-sh2
111c2eyzA_
not modelled 99.8 32 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform ii
112c2cr4A_
not modelled 99.8 18 PDB header:signaling protein
Chain: A: PDB Molecule:sh3 domain-binding protein 2;
PDBTitle: solution structure of the sh2 domain of human sh3bp2 protein
113c2dvjA_
not modelled 99.8 30 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog,
PDBTitle: phosphorylated crk-ii
114d1cwea_
not modelled 99.8 34 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
115c3qwyA_
not modelled 99.8 29 PDB header:signaling protein
Chain: A: PDB Molecule:cell death abnormality protein 2;
PDBTitle: ced-2
116c3qwxX_
not modelled 99.8 29 PDB header:signaling protein
Chain: X: PDB Molecule:cell death abnormality protein 2;
PDBTitle: ced-2 1-174
117c2eyyA_
not modelled 99.8 26 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform i
118c2xp1A_
not modelled 99.8 20 PDB header:transcription
Chain: A: PDB Molecule:spt6;
PDBTitle: structure of the tandem sh2 domains from antonospora locustae2 transcription elongation factor spt6
119c2dx0B_
not modelled 99.7 37 PDB header:hydrolase
Chain: B: PDB Molecule:phospholipase c, gamma 2;
PDBTitle: crystal structure of the n-terminal sh2 domain of mouse2 phospholipase c-gamma 2
120c3or8A_
not modelled 99.7 18 PDB header:transcription
Chain: A: PDB Molecule:transcription elongation factor spt6;
PDBTitle: a tandem sh2 domain in transcription elongation factor spt6

Binding site prediction 

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