Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionQ45FX5
DateFri May 3 21:26:37 BST 2013
Unique Job ID649ae2cb7321d2e3

Summary 

Top model
Image coloured by rainbow N → C terminus
Model dimensions (Å):X:70.882 Y:70.847 Z:80.160
Model (left) based on template c3ky9B_
Top template information
PDB header:apoptosis
Chain: B: PDB Molecule:proto-oncogene vav;
PDBTitle: autoinhibited vav1
Confidence and coverage
Confidence:100.0% Coverage: 53%
534 residues ( 53% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
788 residues ( 78%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MSRRSTTTSTNFGLSWSLVDVISSSTAVFKVPMNGGCDLWIGCARWLRDMKVLTTDKNGT
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   .........70.........80.........90.........100.........110.........120
Sequence  MLEFASVLRDGILLCRLANTLVPNGIDQKKIMRTNQPSPFLCCNNINYFAMFCKTYFNLE
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   .........130.........140.........150.........160.........170.........180
Sequence  DADLFTAEDLYYMNGFQKVLKTLSFLSHTKESLSRGVDPFPDTDNNQEGTSNGSEFEDDV
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   .........190.........200.........210.........220.........230.........240
Sequence  EIYQSLHDNIENVDPNRTIYGPITSADPEEQQSEQLYDRIVTNRKPSMNENDLQNTPTLK
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   .........250.........260.........270.........280.........290.........300
Sequence  RNRCIRELYDTEKNYVAQALVTIIKTFYEPLKGIIPTSDYNIIFGNIEEINVLHTALLAD
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   .........310.........320.........330.........340.........350.........360
Sequence  LEYPVKVALGLSDATPPRPISLNECVPQTIGEVFIKYRDQFLAYGKYCSNLPDSRKLSNE
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   .........370.........380.........390.........400.........410.........420
Sequence  LLKTNEFISRNINELTAQGNCKFGMNDLLCVPFQRLTKYPLLLKELQKKTDLASPDRKSL
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   .........430.........440.........450.........460.........470.........480
Sequence  EEAVEVMEDVCNYINEESRDTNAIKVIDEIEQSITDLSMPLNVKLHDYGRVNLDGEVKMA
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   .........490.........500.........510.........520.........530.........540
Sequence  ESTLTQAGKPKQRYIFLFDKVIVVCKAANKVMAAKTTGASARTNTFTYKNAYVMSELTID
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   .........550.........560.........570.........580.........590.........600
Sequence  KNASLDVKSGGTITRRTQYVIIMTRDRNENNEITQLTFYFKNEATRNNWMTALLLSKSNV
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   .........610.........620.........630.........640.........650.........660
Sequence  SPTDYLRDTNHKVAFHSFRVDVKNPATCDVCDKLMKGLQYQGYKCESCNMSMHKECLGLK
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   .........670.........680.........690.........700.........710.........720
Sequence  KCEAVRKSTHETRSSQSFNCNRPRFHIHEGDIVVANSNSTPSDLSYLQFAKGDRIEVIKM
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   .........730.........740.........750.........760.........770.........780
Sequence  QGHNRFTGCLINNRNRTGLVHLDHVSQSRTTSMIGLSPIDSPAGSIAPRVVRNESTVLPN
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   .........790.........800.........810.........820.........830.........840
Sequence  KLLSDGSSRSLSGPHGSRSSRNSSSSTINGSMDSVPRQQDYVNTEISEFLWYMGEMERAK
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   .........850.........860.........870.........880.........890.........900
Sequence  AESTLKGTPNGTFLVRYSKNRKQTAISLSYKNDVKHMIIEQNSDGKVYLDEDYIFNSTVE
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   .........910.........920.........930.........940.........950.........960
Sequence  LVQYYRSNNLIEIFAALDTCLKNPYSQCKVFKAVHDYDAPSPNNEGKFLSFKTGDIVVLL
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   .........970.........980.........990.........1000.......
Sequence  DTVGEDRGWWKGQVNNKSGFFPLSYVKPYDPATEGSSSPVTPTSSSS
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Confidence Key
High(9)                    Low (0)
?Disordered ( 47%)
Alpha helix ( 30%)
Beta strand ( 12%)

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 3ky9 chain B

3D model

Region: 38 - 664
Aligned: 534
Modelled: 572
Confidence: 100.0%
Identity: 34%
PDB header:apoptosis
Chain: B: PDB Molecule:proto-oncogene vav;
PDBTitle: autoinhibited vav1

Phyre2

PDB 2vrw chain B

3D model

Region: 238 - 663
Aligned: 364
Modelled: 395
Confidence: 100.0%
Identity: 32%
PDB header:signaling protein
Chain: B: PDB Molecule:proto-oncogene vav;
PDBTitle: critical structural role for the ph and c1 domains of the2 vav1 exchange factor

Phyre2

PDB 3bji chain A

3D model

Region: 236 - 664
Aligned: 370
Modelled: 381
Confidence: 100.0%
Identity: 31%
PDB header:signaling protein
Chain: A: PDB Molecule:proto-oncogene vav;
PDBTitle: structural basis of promiscuous guanine nucleotide exchange2 by the t-cell essential vav1

Phyre2

PDB 2dx1 chain A

3D model

Region: 187 - 601
Aligned: 356
Modelled: 373
Confidence: 100.0%
Identity: 22%
PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 4;
PDBTitle: crystal structure of rhogef protein asef

Phyre2

PDB 3ksy chain A

3D model

Region: 240 - 599
Aligned: 318
Modelled: 360
Confidence: 100.0%
Identity: 21%
PDB header:signaling protein
Chain: A: PDB Molecule:son of sevenless homolog 1;
PDBTitle: crystal structure of the histone domain, dh-ph unit, and2 catalytic unit of the ras activator son of sevenless (sos)

Phyre2

PDB 1xdv chain B

3D model

Region: 241 - 599
Aligned: 305
Modelled: 334
Confidence: 100.0%
Identity: 22%
PDB header:signaling protein
Chain: B: PDB Molecule:son of sevenless protein homolog 1;
PDBTitle: experimentally phased structure of human the son of2 sevenless protein at 4.1 ang.

Phyre2

PDB 1xcg chain A

3D model

Region: 222 - 600
Aligned: 335
Modelled: 350
Confidence: 100.0%
Identity: 18%
PDB header:signaling protein activator/signaling pr
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 11;
PDBTitle: crystal structure of human rhoa in complex with dh/ph2 fragment of pdzrhogef

Phyre2

PDB 3odo chain A

3D model

Region: 222 - 599
Aligned: 343
Modelled: 349
Confidence: 100.0%
Identity: 17%
PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 1;
PDBTitle: crystal structure of the dh/ph domains of p115-rhogef

Phyre2

PDB 1foe chain A

3D model

Region: 234 - 604
Aligned: 359
Modelled: 371
Confidence: 100.0%
Identity: 20%
PDB header:signaling protein, immune system/signali
Chain: A: PDB Molecule:t-lymphoma invasion and metastasis inducing
PDBTitle: crystal structure of rac1 in complex with the guanine2 nucleotide exchange region of tiam1

Phyre2

PDB 4gzu chain B

3D model

Region: 239 - 611
Aligned: 310
Modelled: 346
Confidence: 100.0%
Identity: 18%
PDB header:signaling protein
Chain: B: PDB Molecule:ferm, rhogef and pleckstrin domain-containing protein 2;
PDBTitle: crystal strucure of the dh-ph-ph domain of farp2

Phyre2

PDB 3t06 chain E

3D model

Region: 222 - 600
Aligned: 338
Modelled: 350
Confidence: 100.0%
Identity: 18%
PDB header:signaling protein
Chain: E: PDB Molecule:rho guanine nucleotide exchange factor 11;
PDBTitle: crystal structure of the dh/ph fragment of pdzrhogef with n-terminal2 regulatory elements in complex with human rhoa

Phyre2

PDB 4gou chain A

3D model

Region: 232 - 597
Aligned: 317
Modelled: 327
Confidence: 100.0%
Identity: 15%
PDB header:signaling protein
Chain: A: PDB Molecule:ehrgs-rhogef;
PDBTitle: crystal structure of an rgs-rhogef from entamoeba histolytica

Phyre2

PDB 1x86 chain A

3D model

Region: 222 - 604
Aligned: 341
Modelled: 355
Confidence: 100.0%
Identity: 19%
PDB header:signaling protein/membrane protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 12;
PDBTitle: crystal structure of the dh/ph domains of leukemia-associated rhogef2 in complex with rhoa

Phyre2

PDB 2dfk chain A

3D model

Region: 232 - 601
Aligned: 330
Modelled: 355
Confidence: 100.0%
Identity: 24%
PDB header:cell cycle
Chain: A: PDB Molecule:collybistin ii;
PDBTitle: crystal structure of the cdc42-collybistin ii complex

Phyre2

PDB 4h6y chain A

3D model

Region: 239 - 603
Aligned: 293
Modelled: 316
Confidence: 100.0%
Identity: 18%
PDB header:signaling protein
Chain: A: PDB Molecule:ferm, rhogef and pleckstrin domain-containing protein 1;
PDBTitle: crystal strucure of the dh-ph-ph domain of farp1

Phyre2

PDB 1ki1 chain B

3D model

Region: 232 - 600
Aligned: 331
Modelled: 338
Confidence: 100.0%
Identity: 20%
PDB header:signaling protein
Chain: B: PDB Molecule:intersectin long form;
PDBTitle: guanine nucleotide exchange region of intersectin in2 complex with cdc42

Phyre2

PDB 2rgn chain B

3D model

Region: 229 - 599
Aligned: 300
Modelled: 338
Confidence: 100.0%
Identity: 27%
PDB header:signaling protein complex
Chain: B: PDB Molecule:rhoa/rac/cdc42 exchange factor;
PDBTitle: crystal structure of p63rhogef complex with galpha-q and rhoa

Phyre2

PDB 2z0q chain A

3D model

Region: 235 - 598
Aligned: 314
Modelled: 348
Confidence: 100.0%
Identity: 23%
PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 3;
PDBTitle: crystal structure of dh-ph domain of rhogef3(xpln)

Phyre2

PDB 3odx chain A

3D model

Region: 235 - 603
Aligned: 325
Modelled: 340
Confidence: 100.0%
Identity: 17%
PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 1;
PDBTitle: crystal structure of an n-terminally truncated linker-dh/ph domains of2 p115-rhogef

Phyre2

PDB 3mpx chain A

3D model

Region: 239 - 596
Aligned: 293
Modelled: 326
Confidence: 100.0%
Identity: 19%
PDB header:lipid binding protein
Chain: A: PDB Molecule:fyve, rhogef and ph domain-containing protein 5;
PDBTitle: crystal structure of the dh and ph-1 domains of human fgd5

Phyre2

PDB 1gri chain A

3D model

Region: 692 - 990
Aligned: 207
Modelled: 207
Confidence: 99.9%
Identity: 27%
PDB header:signal transduction adaptor
Chain: A: PDB Molecule:growth factor bound protein 2;
PDBTitle: grb2

Phyre2

PDB 2eyy chain A

3D model

Region: 825 - 998
Aligned: 172
Modelled: 172
Confidence: 99.9%
Identity: 27%
PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform i

Phyre2

PDB 2dvj chain A

3D model

Region: 825 - 1007
Aligned: 177
Modelled: 177
Confidence: 99.9%
Identity: 29%
PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog,
PDBTitle: phosphorylated crk-ii

Phyre2

PDB 2lqn chain A

3D model

Region: 825 - 1007
Aligned: 180
Modelled: 180
Confidence: 99.9%
Identity: 23%
PDB header:signaling protein
Chain: A: PDB Molecule:crk-like protein;
PDBTitle: solution structure of crkl

Phyre2

PDB 2eyz chain A

3D model

Region: 825 - 1007
Aligned: 177
Modelled: 177
Confidence: 99.8%
Identity: 28%
PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform ii

Phyre2

PDB 3qwx chain X

3D model

Region: 827 - 988
Aligned: 152
Modelled: 152
Confidence: 99.8%
Identity: 22%
PDB header:signaling protein
Chain: X: PDB Molecule:cell death abnormality protein 2;
PDBTitle: ced-2 1-174

Phyre2
1

c3ky9B_
2

c2vrwB_
3

c3bjiA_
4

c2dx1A_
5

c3ksyA_
6

c1xdvB_
7

c1xcgA_
8

c3odoA_
9

c1foeA_
10

c4gzuB_
11

c3t06E_
12

c4gouA_
13

c1x86A_
14

c2dfkA_
15

c4h6yA_
16

c1ki1B_
17

c2rgnB_
18

c2z0qA_
19

c3odxA_
20

c3mpxA_
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c1griA_
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c2eyyA_
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c2dvjA_
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c2lqnA_
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c2eyzA_
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c3qwxX_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c3ky9B_



100.0 34 PDB header:apoptosis
Chain: B: PDB Molecule:proto-oncogene vav;
PDBTitle: autoinhibited vav1
2c2vrwB_



100.0 32 PDB header:signaling protein
Chain: B: PDB Molecule:proto-oncogene vav;
PDBTitle: critical structural role for the ph and c1 domains of the2 vav1 exchange factor
3c3bjiA_



100.0 31 PDB header:signaling protein
Chain: A: PDB Molecule:proto-oncogene vav;
PDBTitle: structural basis of promiscuous guanine nucleotide exchange2 by the t-cell essential vav1
4c2dx1A_



100.0 22 PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 4;
PDBTitle: crystal structure of rhogef protein asef
5c3ksyA_



100.0 21 PDB header:signaling protein
Chain: A: PDB Molecule:son of sevenless homolog 1;
PDBTitle: crystal structure of the histone domain, dh-ph unit, and2 catalytic unit of the ras activator son of sevenless (sos)
6c1xdvB_



100.0 22 PDB header:signaling protein
Chain: B: PDB Molecule:son of sevenless protein homolog 1;
PDBTitle: experimentally phased structure of human the son of2 sevenless protein at 4.1 ang.
7c1xcgA_



100.0 18 PDB header:signaling protein activator/signaling pr
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 11;
PDBTitle: crystal structure of human rhoa in complex with dh/ph2 fragment of pdzrhogef
8c3odoA_



100.0 17 PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 1;
PDBTitle: crystal structure of the dh/ph domains of p115-rhogef
9c1foeA_



100.0 20 PDB header:signaling protein, immune system/signali
Chain: A: PDB Molecule:t-lymphoma invasion and metastasis inducing
PDBTitle: crystal structure of rac1 in complex with the guanine2 nucleotide exchange region of tiam1
10c4gzuB_



100.0 18 PDB header:signaling protein
Chain: B: PDB Molecule:ferm, rhogef and pleckstrin domain-containing protein 2;
PDBTitle: crystal strucure of the dh-ph-ph domain of farp2
11c3t06E_



100.0 18 PDB header:signaling protein
Chain: E: PDB Molecule:rho guanine nucleotide exchange factor 11;
PDBTitle: crystal structure of the dh/ph fragment of pdzrhogef with n-terminal2 regulatory elements in complex with human rhoa
12c4gouA_



100.0 15 PDB header:signaling protein
Chain: A: PDB Molecule:ehrgs-rhogef;
PDBTitle: crystal structure of an rgs-rhogef from entamoeba histolytica
13c1x86A_



100.0 19 PDB header:signaling protein/membrane protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 12;
PDBTitle: crystal structure of the dh/ph domains of leukemia-associated rhogef2 in complex with rhoa
14c2dfkA_



100.0 24 PDB header:cell cycle
Chain: A: PDB Molecule:collybistin ii;
PDBTitle: crystal structure of the cdc42-collybistin ii complex
15c4h6yA_



100.0 18 PDB header:signaling protein
Chain: A: PDB Molecule:ferm, rhogef and pleckstrin domain-containing protein 1;
PDBTitle: crystal strucure of the dh-ph-ph domain of farp1
16c1ki1B_



100.0 20 PDB header:signaling protein
Chain: B: PDB Molecule:intersectin long form;
PDBTitle: guanine nucleotide exchange region of intersectin in2 complex with cdc42
17c2rgnB_



100.0 27 PDB header:signaling protein complex
Chain: B: PDB Molecule:rhoa/rac/cdc42 exchange factor;
PDBTitle: crystal structure of p63rhogef complex with galpha-q and rhoa
18c2z0qA_



100.0 23 PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 3;
PDBTitle: crystal structure of dh-ph domain of rhogef3(xpln)
19c3odxA_



100.0 17 PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 1;
PDBTitle: crystal structure of an n-terminally truncated linker-dh/ph domains of2 p115-rhogef
20c3mpxA_



100.0 19 PDB header:lipid binding protein
Chain: A: PDB Molecule:fyve, rhogef and ph domain-containing protein 5;
PDBTitle: crystal structure of the dh and ph-1 domains of human fgd5
21c3odwB_



not modelled 100.0 16 PDB header:signaling protein
Chain: B: PDB Molecule:rho guanine nucleotide exchange factor 1;
PDBTitle: crystal structure of the linker-dh/ph domains of p115-rhogef
22c1dbhA_



not modelled 100.0 20 PDB header:gene regulation
Chain: A: PDB Molecule:protein (human sos 1);
PDBTitle: dbl and pleckstrin homology domains from hsos1
23c1lb1C_



not modelled 100.0 24 PDB header:signaling protein
Chain: C: PDB Molecule:guanine nucleotide exchange factor dbs;
PDBTitle: crystal structure of the dbl and pleckstrin homology2 domains of dbs in complex with rhoa
24c1ntyA_



not modelled 100.0 24 PDB header:signaling protein
Chain: A: PDB Molecule:triple functional domain protein;
PDBTitle: crystal structure of the first dh/ph domain of trio to 1.7 a
25c3jv3A_



not modelled 100.0 22 PDB header:protein binding
Chain: A: PDB Molecule:intersectin-1;
PDBTitle: structure of sh3e-dh unit of murine intersectin-1l
26d1xcga1



not modelled 100.0 19 Fold:DBL homology domain (DH-domain)
Superfamily:DBL homology domain (DH-domain)
Family:DBL homology domain (DH-domain)
27c4gyvA_



not modelled 100.0 21 PDB header:signaling protein
Chain: A: PDB Molecule:ferm, rhogef and pleckstrin domain-containing protein 2;
PDBTitle: crystal strucure of the dh domain of farp2
28d1dbha1



not modelled 100.0 20 Fold:DBL homology domain (DH-domain)
Superfamily:DBL homology domain (DH-domain)
Family:DBL homology domain (DH-domain)
29d1txda1



not modelled 100.0 24 Fold:DBL homology domain (DH-domain)
Superfamily:DBL homology domain (DH-domain)
Family:DBL homology domain (DH-domain)
30d1ki1b1



not modelled 100.0 25 Fold:DBL homology domain (DH-domain)
Superfamily:DBL homology domain (DH-domain)
Family:DBL homology domain (DH-domain)
31d2dfka1



not modelled 100.0 27 Fold:DBL homology domain (DH-domain)
Superfamily:DBL homology domain (DH-domain)
Family:DBL homology domain (DH-domain)
32d1foea1



not modelled 100.0 27 Fold:DBL homology domain (DH-domain)
Superfamily:DBL homology domain (DH-domain)
Family:DBL homology domain (DH-domain)
33d1f5xa_



not modelled 100.0 36 Fold:DBL homology domain (DH-domain)
Superfamily:DBL homology domain (DH-domain)
Family:DBL homology domain (DH-domain)
34c3eo2A_



not modelled 100.0 30 PDB header:splicing
Chain: A: PDB Molecule:neuroepithelial cell-transforming gene 1 protein;
PDBTitle: crystal structure of the rhogef domain of human neuroepithelial cell-2 transforming gene 1 protein
35c2d86A_



not modelled 100.0 40 PDB header:signaling protein, protein binding
Chain: A: PDB Molecule:vav-3 protein;
PDBTitle: solution structure of the ch domain from human vav-3 protein
36d1ntya1



not modelled 100.0 30 Fold:DBL homology domain (DH-domain)
Superfamily:DBL homology domain (DH-domain)
Family:DBL homology domain (DH-domain)
37d1by1a_



not modelled 100.0 26 Fold:DBL homology domain (DH-domain)
Superfamily:DBL homology domain (DH-domain)
Family:DBL homology domain (DH-domain)
38d1kz7a1



not modelled 100.0 27 Fold:DBL homology domain (DH-domain)
Superfamily:DBL homology domain (DH-domain)
Family:DBL homology domain (DH-domain)
39c3gf9A_



not modelled 100.0 28 PDB header:endocytosis
Chain: A: PDB Molecule:intersectin 2;
PDBTitle: crystal structure of human intersectin 2 rhogef domain
40d1ujoa_



not modelled 99.9 21 Fold:CH domain-like
Superfamily:Calponin-homology domain, CH-domain
Family:Calponin-homology domain, CH-domain
41c1griA_



99.9 27 PDB header:signal transduction adaptor
Chain: A: PDB Molecule:growth factor bound protein 2;
PDBTitle: grb2
42c2l3gA_



not modelled 99.9 32 PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 7;
PDBTitle: solution nmr structure of ch domain of rho guanine nucleotide exchange2 factor 7 from homo sapiens, northeast structural genomics consortium3 target hr4495e
43c1wymA_



not modelled 99.9 20 PDB header:structural protein
Chain: A: PDB Molecule:transgelin-2;
PDBTitle: solution structure of the ch domain of human transgelin-2
44c2eyyA_



99.9 27 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform i
45c1wyrA_



not modelled 99.9 32 PDB header:structural protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 6;
PDBTitle: solution structure of the ch domain of human rho guanine2 nucleotide exchange factor 6
46c2dvjA_



99.9 29 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog,
PDBTitle: phosphorylated crk-ii
47c2lqnA_



99.9 23 PDB header:signaling protein
Chain: A: PDB Molecule:crk-like protein;
PDBTitle: solution structure of crkl
48c2eyzA_



99.8 28 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform ii
49c1wypA_



not modelled 99.8 25 PDB header:structural protein
Chain: A: PDB Molecule:calponin 1;
PDBTitle: solution structure of the ch domain of human calponin 1
50c3qwxX_



99.8 22 PDB header:signaling protein
Chain: X: PDB Molecule:cell death abnormality protein 2;
PDBTitle: ced-2 1-174
51c3qwyA_



not modelled 99.8 22 PDB header:signaling protein
Chain: A: PDB Molecule:cell death abnormality protein 2;
PDBTitle: ced-2
52c1wynA_



not modelled 99.8 23 PDB header:structural protein
Chain: A: PDB Molecule:calponin-2;
PDBTitle: solution structure of the ch domain of human calponin-2
53c1mv3A_



not modelled 99.8 14 PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:myc box dependent interacting protein 1;
PDBTitle: nmr structure of the tumor suppressor bin1: alternative2 splicing in melanoma and interaction with c-myc
54c2l3sA_



not modelled 99.8 21 PDB header:structural protein
Chain: A: PDB Molecule:autoinhibited crk protein;
PDBTitle: structure of the autoinhibited crk
55d1p2xa_



not modelled 99.8 23 Fold:CH domain-like
Superfamily:Calponin-homology domain, CH-domain
Family:Calponin-homology domain, CH-domain
56c1p5sA_



not modelled 99.8 23 PDB header:cytokine
Chain: A: PDB Molecule:ras gtpase-activating-like protein rng2;
PDBTitle: structure and function of the calponin-homology domain of2 an iqgap protein from schizosaccharomyces pombe
57c2rr8A_



not modelled 99.8 17 PDB header:protein binding
Chain: A: PDB Molecule:iqgap1 protein;
PDBTitle: solution structure of calponin homology domain of iqgap1
58d1h67a_



not modelled 99.8 25 Fold:CH domain-like
Superfamily:Calponin-homology domain, CH-domain
Family:Calponin-homology domain, CH-domain
59c3i6xC_



not modelled 99.8 18 PDB header:calmodulin-binding, membrane protein
Chain: C: PDB Molecule:ras gtpase-activating-like protein iqgap1;
PDBTitle: crystal structure of the calponin homology domain of iqgap1
60c1ng2A_



not modelled 99.8 17 PDB header:oxidoreductase activator
Chain: A: PDB Molecule:neutrophil cytosolic factor 1;
PDBTitle: structure of autoinhibited p47phox
61c1ov3A_



not modelled 99.7 26 PDB header:oxidoreductase activator
Chain: A: PDB Molecule:neutrophil cytosol factor 1;
PDBTitle: structure of the p22phox-p47phox complex
62c2lg1A_



not modelled 99.7 14 PDB header:metal binding protein
Chain: A: PDB Molecule:a-kinase anchor protein 13;
PDBTitle: solution structure of the human akap13 ph domain and stabilizing dh2 helix
63d1ng2a2



not modelled 99.7 14 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
64c2dlpA_



not modelled 99.6 28 PDB header:structural protein
Chain: A: PDB Molecule:kiaa1783 protein;
PDBTitle: solution structure of the sh3 domain of human kiaa17832 protein
65c1x2qA_



not modelled 99.6 25 PDB header:signaling protein
Chain: A: PDB Molecule:signal transducing adapter molecule 2;
PDBTitle: solution structure of the sh3 domain of the signal2 transducing adaptor molecule 2
66c2cubA_



not modelled 99.6 23 PDB header:signaling protein
Chain: A: PDB Molecule:cytoplasmic protein nck1;
PDBTitle: solution structure of the sh3 domain of the human2 cytoplasmic protein nck1
67c2yunA_



not modelled 99.6 25 PDB header:protein transport
Chain: A: PDB Molecule:nostrin;
PDBTitle: solution structure of the sh3 domain of human nostrin
68d1ug1a_



not modelled 99.6 21 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
69c2e5kA_



not modelled 99.6 19 PDB header:protein binding
Chain: A: PDB Molecule:suppressor of t-cell receptor signaling 1;
PDBTitle: solution structure of sh3 domain in suppressor of t-cell2 receptor signaling 1
70c2dbkA_



not modelled 99.6 24 PDB header:signaling protein
Chain: A: PDB Molecule:crk-like protein;
PDBTitle: solution structures of the sh3 domain of human crk-like2 protein
71c2yuoA_



not modelled 99.6 23 PDB header:signaling protein
Chain: A: PDB Molecule:run and tbc1 domain containing 3;
PDBTitle: solution structure of the sh3 domain of mouse run and tbc12 domain containing 3
72c2csqA_



not modelled 99.6 23 PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:rim binding protein 2;
PDBTitle: solution structure of the second sh3 domain of human rim-2 binding protein 2
73d1ov3a2



not modelled 99.6 25 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
74c2ekhA_



not modelled 99.6 20 PDB header:signaling protein
Chain: A: PDB Molecule:sh3 and px domain-containing protein 2a;
PDBTitle: solution structures of the sh3 domain of human kiaa0418
75c3nmzD_



not modelled 99.6 23 PDB header:cell adhesion/cell cycle
Chain: D: PDB Molecule:rho guanine nucleotide exchange factor 4;
PDBTitle: crytal structure of apc complexed with asef
76c2rqrA_



not modelled 99.6 12 PDB header:protein binding
Chain: A: PDB Molecule:engulfment and cell motility protein 1, linker, dedicator
PDBTitle: the solution structure of human dock2 sh3 domain - elmo1 peptide2 chimera complex
77d1ue9a_



not modelled 99.6 28 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
78c2dmoA_



not modelled 99.6 23 PDB header:signaling protein
Chain: A: PDB Molecule:neutrophil cytosol factor 2;
PDBTitle: refined solution structure of the 1st sh3 domain from human2 neutrophil cytosol factor 2 (ncf-2)
79c2yupA_



not modelled 99.5 20 PDB header:cell adhesion
Chain: A: PDB Molecule:vinexin;
PDBTitle: solution structure of the second sh3 domain of human vinexin
80c2ebpA_



not modelled 99.5 25 PDB header:cell adhesion
Chain: A: PDB Molecule:sam and sh3 domain-containing protein 1;
PDBTitle: solution structure of the sh3 domain from human sam and sh32 domain containing protein 1
81c2ed0A_



not modelled 99.5 22 PDB header:signaling protein
Chain: A: PDB Molecule:abl interactor 2;
PDBTitle: solution structure of the sh3 domain of abl interactor 22 (abelson interactor 2)
82c2eyxA_



not modelled 99.5 22 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: c-terminal sh3 domain of ct10-regulated kinase
83c1x43A_



not modelled 99.5 20 PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:sh3 domain grb2-like protein b1;
PDBTitle: solution structure of the sh3 domain of endophilin b12 (sh3g1b1)
84c2dl4A_



not modelled 99.5 28 PDB header:signaling protein
Chain: A: PDB Molecule:protein stac;
PDBTitle: solution structure of the first sh3 domain of stac protein
85c2dnuA_



not modelled 99.5 23 PDB header:structural genomics, structural protein
Chain: A: PDB Molecule:sh3 multiple domains 1;
PDBTitle: solution structure of rsgi ruh-061, a sh3 domain from human
86c2djqA_



not modelled 99.5 30 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:sh3 domain containing ring finger 2;
PDBTitle: the solution structure of the first sh3 domain of mouse sh32 domain containing ring finger 2
87c2kymA_



not modelled 99.5 18 PDB header:signaling protein
Chain: A: PDB Molecule:bud emergence protein 1;
PDBTitle: solution structure of the bem1p sh3-ci domain from l.elongisporus in2 complex with ste20p peptide
88c2d8hA_



not modelled 99.5 19 PDB header:unknown function
Chain: A: PDB Molecule:sh3yl1 protein;
PDBTitle: solution structure of the sh3 domain of hypothetical2 protein sh3yl1
89d1oeba_



not modelled 99.5 37 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
90d1uffa_



not modelled 99.5 19 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
91c1wx6A_



not modelled 99.5 17 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:cytoplasmic protein nck2;
PDBTitle: solution structure of the sh3 domain of the human2 cytoplasmic protein nck2
92d1udla_



not modelled 99.5 20 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
93d1sema_



not modelled 99.5 38 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
94c2ysqA_



not modelled 99.5 23 PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 9;
PDBTitle: solution structure of the sh3 domain from rho guanine2 nucleotide exchange factor 9
95d1wiea_



not modelled 99.5 13 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
96c2yt6A_



not modelled 99.5 18 PDB header:cell cycle
Chain: A: PDB Molecule:adult male urinary bladder cdna, riken full-
PDBTitle: solution structure of the sh3_1 domain of yamaguchi sarcoma2 viral (v-yes) oncogene homolog 1
97c2df6A_



not modelled 99.5 31 PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 7;
PDBTitle: crystal structure of the sh3 domain of betapix in complex2 with a high affinity peptide from pak2
98c2fpeB_



not modelled 99.5 15 PDB header:signaling protein
Chain: B: PDB Molecule:c-jun-amino-terminal kinase interacting protein
PDBTitle: conserved dimerization of the ib1 src-homology 3 domain
99c1zx6A_



not modelled 99.5 34 PDB header:protein binding
Chain: A: PDB Molecule:ypr154wp;
PDBTitle: high-resolution crystal structure of yeast pin3 sh3 domain
100c4igzA_



not modelled 99.5 27 PDB header:protein binding
Chain: A: PDB Molecule:sorbin and sh3 domain-containing protein 2;
PDBTitle: crystal structure of the sh3 domain of human sorbin and sh3 domain-2 containing protein 2
101c2rf0D_



not modelled 99.5 33 PDB header:transferase
Chain: D: PDB Molecule:mitogen-activated protein kinase kinase kinase 10;
PDBTitle: crystal structure of human mixed lineage kinase map3k10 sh3 domain
102c2dilA_



not modelled 99.5 25 PDB header:cell adhesion
Chain: A: PDB Molecule:proline-serine-threonine phosphatase-interacting
PDBTitle: solution structure of the sh3 domain of the human proline-2 serine-threonine phosphatase-interacting protein 1
103c2dl8A_



not modelled 99.5 26 PDB header:signaling protein
Chain: A: PDB Molecule:slit-robo rho gtpase-activating protein 2;
PDBTitle: solution structure of the sh3 domain of human slit-robo rho2 gtpase-activating protein 2
104d1uuea_



not modelled 99.5 33 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
105c2i0nA_



not modelled 99.5 24 PDB header:structural protein
Chain: A: PDB Molecule:class vii unconventional myosin;
PDBTitle: structure of dictyostelium discoideum myosin vii sh3 domain2 with adjacent proline rich region
106c2dl3A_



not modelled 99.5 23 PDB header:cell adhesion, signaling protein
Chain: A: PDB Molecule:sorbin and sh3 domain-containing protein 1;
PDBTitle: solution structure of the first sh3 domain of human sorbin2 and sh3 domain-containing protein 1
107d1nega_



not modelled 99.5 30 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
108c1negA_



not modelled 99.5 30 PDB header:structural protein
Chain: A: PDB Molecule:spectrin alpha chain, brain;
PDBTitle: crystal structure analysis of n-and c-terminal labeled sh3-2 domain of alpha-chicken spectrin
109c2nwmA_



not modelled 99.5 27 PDB header:cell adhesion
Chain: A: PDB Molecule:vinexin;
PDBTitle: solution structure of the first sh3 domain of human vinexin2 and its interaction with the peptides from vinculin
110c2oi3A_



not modelled 99.5 24 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase hck;
PDBTitle: nmr structure analysis of the hematopoetic cell kinase sh32 domain complexed with an artificial high affinity ligand3 (pd1)
111c2ct3A_



not modelled 99.5 27 PDB header:signaling protein
Chain: A: PDB Molecule:vinexin;
PDBTitle: solution structure of the sh3 domain of the vinexin protein
112c1zlmA_



not modelled 99.5 30 PDB header:signaling protein
Chain: A: PDB Molecule:osteoclast stimulating factor 1;
PDBTitle: crystal structure of the sh3 domain of human osteoclast2 stimulating factor
113c2cudA_



not modelled 99.5 17 PDB header:signaling protein
Chain: A: PDB Molecule:src-like-adapter;
PDBTitle: solution structure of the sh3 domain of the human src-like2 adopter protein (slap)
114d1wlpb2



not modelled 99.5 26 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
115d1gcqc_



not modelled 99.5 34 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
116c1wyxA_



not modelled 99.5 22 PDB header:cell adhesion
Chain: A: PDB Molecule:crk-associated substrate;
PDBTitle: the crystal structure of the p130cas sh3 domain at 1.1 a2 resolution
117c2k6dA_



not modelled 99.5 34 PDB header:sh3 domain/ubiquitin
Chain: A: PDB Molecule:sh3 domain-containing kinase-binding protein 1;
PDBTitle: cin85 sh3-c domain in complex with ubiquitin
118c2eqiA_



not modelled 99.5 23 PDB header:immune system, hydrolase
Chain: A: PDB Molecule:phospholipase c, gamma 2;
PDBTitle: solution structure of the sh3 domain from phospholipase c,2 gamma 2
119d1pwta_



not modelled 99.5 33 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
120c3rnjA_



not modelled 99.5 34 PDB header:protein binding
Chain: A: PDB Molecule:brain-specific angiogenesis inhibitor 1-associated protein
PDBTitle: crystal structure of the sh3 domain from irsp53 (baiap2)

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