Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionQ8R4L0
DateTue Jul 30 13:18:27 BST 2013
Unique Job ID0a7e693b9aaa9644
SequenceMGSLSSRGKT ... Download FASTA

Summary 

Top model
Image coloured by rainbow N → C terminus
Model dimensions (Å):X:80.339 Y:47.718 Z:48.946
Model (left) based on template c1y57A_
Top template information
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor
Confidence and coverage
Confidence:100.0% Coverage: 76%
196 residues ( 76% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
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Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MGSLSSRGKTSSPSPSSSGPDQEPVSMQPERHKVTAVALGSFPAGEQARLSLRLGEPLTI
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Disorder  ?????????????????????????????????










?
???










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   .........70.........80.........90.........100.........110.........120
Sequence  ISEDGDWWTVQSEVSGREYHMPSVYVAKVAHGWLYEGLSREKAEELLLLPGNPGGAFLIR
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Disorder 




?





???????








































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   .........130.........140.........150.........160.........170.........180
Sequence  ESQTRRGCYSLSVRLSRPASWDRIRHYRIQRLDNGWLYISPRLTFPSLHALVEHYSELAD
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??








































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   .........190.........200.........210.........220.........230.........240
Sequence  GICCPLREPCVLQKLGPLPGKDTPPPVTVPTSSLNWKKLDRSLLFLEAPASGEASLLSEG
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Disorder 









???????????????????????????














?






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   .........250.........
Sequence  LRESLSSYISLAEDPLDDA
Secondary structure 




SS confidence 


















Disorder 











???????
Disorder confidence 


















 

Confidence Key
High(9)                    Low (0)
?Disordered ( 32%)
Alpha helix ( 10%)
Beta strand ( 27%)

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1y57 chain A

3D model

Region: 34 - 240
Aligned: 196
Modelled: 196
Confidence: 100.0%
Identity: 37%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor

Phyre2

PDB 2c0i chain A

3D model

Region: 35 - 240
Aligned: 194
Modelled: 194
Confidence: 100.0%
Identity: 38%
PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase hck;
PDBTitle: src family kinase hck with bound inhibitor a-420983

Phyre2

PDB 2h8h chain A

3D model

Region: 35 - 240
Aligned: 195
Modelled: 195
Confidence: 100.0%
Identity: 37%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: src kinase in complex with a quinazoline inhibitor

Phyre2

PDB 2fo0 chain A

3D model

Region: 25 - 240
Aligned: 201
Modelled: 216
Confidence: 100.0%
Identity: 30%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase abl1 (1b isoform);
PDBTitle: organization of the sh3-sh2 unit in active and inactive forms of the2 c-abl tyrosine kinase

Phyre2

PDB 1opl chain A

3D model

Region: 32 - 240
Aligned: 194
Modelled: 209
Confidence: 100.0%
Identity: 30%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase;
PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase

Phyre2

PDB 1x27 chain F

3D model

Region: 34 - 190
Aligned: 157
Modelled: 157
Confidence: 100.0%
Identity: 45%
PDB header:signaling protein
Chain: F: PDB Molecule:proto-oncogene tyrosine-protein kinase lck;
PDBTitle: crystal structure of lck sh2-sh3 with sh2 binding site of2 p130cas

Phyre2

PDB 3nhn chain A

3D model

Region: 33 - 191
Aligned: 159
Modelled: 159
Confidence: 100.0%
Identity: 43%
PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase hck;
PDBTitle: crystal structure of the src-family kinase hck sh3-sh2-linker2 regulatory region

Phyre2

PDB 1k9a chain B

3D model

Region: 29 - 240
Aligned: 195
Modelled: 212
Confidence: 100.0%
Identity: 30%
PDB header:transferase
Chain: B: PDB Molecule:carboxyl-terminal src kinase;
PDBTitle: crystal structure analysis of full-length carboxyl-terminal2 src kinase at 2.5 a resolution

Phyre2

PDB 2abl chain A

3D model

Region: 27 - 191
Aligned: 158
Modelled: 165
Confidence: 100.0%
Identity: 33%
PDB header:transferase
Chain: A: PDB Molecule:abl tyrosine kinase;
PDBTitle: sh3-sh2 domain fragment of human bcr-abl tyrosine kinase

Phyre2

PDB 1g83 chain A

3D model

Region: 35 - 189
Aligned: 155
Modelled: 155
Confidence: 100.0%
Identity: 44%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fyn;
PDBTitle: crystal structure of fyn sh3-sh2

Phyre2

PDB 1a81 chain A domain 1

3D model

Region: 91 - 222
Aligned: 123
Modelled: 132
Confidence: 100.0%
Identity: 28%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2

PDB 2oq1 chain A domain 1

3D model

Region: 87 - 197
Aligned: 106
Modelled: 111
Confidence: 100.0%
Identity: 33%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2

PDB 1lkk chain A

3D model

Region: 88 - 190
Aligned: 103
Modelled: 103
Confidence: 100.0%
Identity: 50%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2

PDB 2oq1 chain A

3D model

Region: 91 - 250
Aligned: 147
Modelled: 160
Confidence: 100.0%
Identity: 26%
PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase zap-70;
PDBTitle: tandem sh2 domains of zap-70 with 19-mer zeta1 peptide

Phyre2

PDB 1qcf chain A domain 2

3D model

Region: 91 - 191
Aligned: 101
Modelled: 101
Confidence: 100.0%
Identity: 50%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2

PDB 1f2f chain A

3D model

Region: 90 - 190
Aligned: 101
Modelled: 101
Confidence: 100.0%
Identity: 45%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2

PDB 1bkl chain A

3D model

Region: 91 - 194
Aligned: 104
Modelled: 104
Confidence: 100.0%
Identity: 43%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2

PDB 2dly chain A

3D model

Region: 76 - 197
Aligned: 117
Modelled: 122
Confidence: 100.0%
Identity: 35%
PDB header:transferase
Chain: A: PDB Molecule:fyn-related kinase;
PDBTitle: solution structure of the sh2 domain of murine fyn-related2 kinase

Phyre2

PDB 2oq1 chain A domain 2

3D model

Region: 86 - 191
Aligned: 100
Modelled: 106
Confidence: 100.0%
Identity: 32%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2

PDB 1g83 chain A domain 2

3D model

Region: 87 - 189
Aligned: 103
Modelled: 103
Confidence: 100.0%
Identity: 47%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2

PDB 2yt6 chain A

3D model

Region: 2 - 104
Aligned: 98
Modelled: 98
Confidence: 99.6%
Identity: 35%
PDB header:cell cycle
Chain: A: PDB Molecule:adult male urinary bladder cdna, riken full-
PDBTitle: solution structure of the sh3_1 domain of yamaguchi sarcoma2 viral (v-yes) oncogene homolog 1

Phyre2
1

c1y57A_
2

c2c0iA_
3

c2h8hA_
4

c2fo0A_
5

c1oplA_
6

c1x27F_
7

c3nhnA_
8

c1k9aB_
9

c2ablA_
10

c1g83A_
11

d1a81a1
12

d2oq1a1
13

d1lkka_
14

c2oq1A_
15

d1qcfa2
16

d1f2fa_
17

d1bkla_
18

c2dlyA_
19

d2oq1a2
20

d1g83a2
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c2yt6A_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c1y57A_



100.0 37 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor
2c2c0iA_



100.0 38 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase hck;
PDBTitle: src family kinase hck with bound inhibitor a-420983
3c2h8hA_



100.0 37 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: src kinase in complex with a quinazoline inhibitor
4c2fo0A_



100.0 30 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase abl1 (1b isoform);
PDBTitle: organization of the sh3-sh2 unit in active and inactive forms of the2 c-abl tyrosine kinase
5c1oplA_



100.0 30 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase;
PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase
6c1x27F_



100.0 45 PDB header:signaling protein
Chain: F: PDB Molecule:proto-oncogene tyrosine-protein kinase lck;
PDBTitle: crystal structure of lck sh2-sh3 with sh2 binding site of2 p130cas
7c3nhnA_



100.0 43 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase hck;
PDBTitle: crystal structure of the src-family kinase hck sh3-sh2-linker2 regulatory region
8c1k9aB_



100.0 30 PDB header:transferase
Chain: B: PDB Molecule:carboxyl-terminal src kinase;
PDBTitle: crystal structure analysis of full-length carboxyl-terminal2 src kinase at 2.5 a resolution
9c2ablA_



100.0 33 PDB header:transferase
Chain: A: PDB Molecule:abl tyrosine kinase;
PDBTitle: sh3-sh2 domain fragment of human bcr-abl tyrosine kinase
10c1g83A_



100.0 44 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fyn;
PDBTitle: crystal structure of fyn sh3-sh2
11d1a81a1



100.0 28 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
12d2oq1a1



100.0 33 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
13d1lkka_



100.0 50 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
14c2oq1A_



100.0 26 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase zap-70;
PDBTitle: tandem sh2 domains of zap-70 with 19-mer zeta1 peptide
15d1qcfa2



100.0 50 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
16d1f2fa_



100.0 45 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
17d1bkla_



100.0 43 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
18c2dlyA_



100.0 35 PDB header:transferase
Chain: A: PDB Molecule:fyn-related kinase;
PDBTitle: solution structure of the sh2 domain of murine fyn-related2 kinase
19d2oq1a2



100.0 32 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
20d1g83a2



100.0 47 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
21d1o48a_



not modelled 100.0 42 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
22d1blja_



not modelled 100.0 46 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
23d1a81e1



not modelled 100.0 30 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
24c2ozoA_



not modelled 100.0 33 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase zap-70;
PDBTitle: autoinhibited intact human zap-70
25c4fl2A_



not modelled 100.0 33 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase syk;
PDBTitle: structural and biophysical characterization of the syk activation2 switch
26d1rjaa_



not modelled 100.0 34 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
27d1a81a2



not modelled 100.0 35 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
28d1a81e2



not modelled 100.0 36 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
29c2eo3A_



not modelled 100.0 33 PDB header:signaling protein
Chain: A: PDB Molecule:crk-like protein;
PDBTitle: solution structure of the sh2 domain from human crk-like2 protein
30d1csya_



not modelled 99.9 31 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
31c2b3oA_



not modelled 99.9 29 PDB header:hydrolase
Chain: A: PDB Molecule:tyrosine-protein phosphatase, non-receptor type
PDBTitle: crystal structure of human tyrosine phosphatase shp-1
32d1nrva_



not modelled 99.9 22 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
33d1cwea_



not modelled 99.9 51 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
34c2ysxA_



not modelled 99.9 30 PDB header:signaling protein
Chain: A: PDB Molecule:signaling inositol polyphosphate phosphatase
PDBTitle: solution structure of the human ship sh2 domain
35c2knoA_



not modelled 99.9 30 PDB header:hydrolase
Chain: A: PDB Molecule:tensin-like c1 domain-containing phosphatase;
PDBTitle: nmr solution structure of sh2 domain of the human tensin like c12 domain containing phosphatase (tenc1)
36c2augB_



not modelled 99.9 25 PDB header:signaling protein
Chain: B: PDB Molecule:growth factor receptor-bound protein 14;
PDBTitle: crystal structure of the grb14 sh2 domain
37c2ge9A_



not modelled 99.9 25 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase btk;
PDBTitle: solution structures of the sh2 domain of bruton's tyrosine2 kinase
38c2el8A_



not modelled 99.9 21 PDB header:signaling protein
Chain: A: PDB Molecule:signal-transducing adaptor protein 2;
PDBTitle: solution structure of the human stap2 sh2 domain
39c1a81E_



not modelled 99.9 36 PDB header:complex (transferase/peptide)
Chain: E: PDB Molecule:syk kinase;
PDBTitle: crystal structure of the tandem sh2 domain of the syk kinase bound to2 a dually tyrosine-phosphorylated itam
40c2eo6A_



not modelled 99.9 21 PDB header:signaling protein
Chain: A: PDB Molecule:b-cell linker protein;
PDBTitle: solution structure of the sh2 domain from mouse b-cell2 linker protein blnk
41d2qmsa1



not modelled 99.9 29 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
42c3hizB_



not modelled 99.9 28 PDB header:transferase/oncoprotein
Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit
PDBTitle: crystal structure of p110alpha h1047r mutant in complex with2 nish2 of p85alpha
43c2lqnA_



not modelled 99.9 30 PDB header:signaling protein
Chain: A: PDB Molecule:crk-like protein;
PDBTitle: solution structure of crkl
44c1ka6A_



not modelled 99.9 28 PDB header:immune system
Chain: A: PDB Molecule:sh2 domain protein 1a;
PDBTitle: sap/sh2d1a bound to peptide n-py
45d1opka2



not modelled 99.9 38 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
46c2dm0A_



not modelled 99.9 27 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase txk;
PDBTitle: solution structure of the sh2 domain of human tyrosine-2 protein kinase txk
47c2y3aB_



not modelled 99.9 35 PDB header:transferase
Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit beta;
PDBTitle: crystal structure of p110beta in complex with icsh2 of p85beta and2 the drug gdc-0941
48c2gsbA_



not modelled 99.9 23 PDB header:signaling protein
Chain: A: PDB Molecule:ras gtpase-activating protein 1;
PDBTitle: solution structure of the second sh2 domain of human ras2 gtpase-activating protein 1
49d1d4ta_



not modelled 99.9 30 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
50d1k9aa2



not modelled 99.9 35 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
51d1i3za_



not modelled 99.9 34 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
52c2shpA_



not modelled 99.9 29 PDB header:tyrosine phosphatase
Chain: A: PDB Molecule:shp-2;
PDBTitle: tyrosine phosphatase shp-2
53d1luia_



not modelled 99.9 32 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
54d1jwoa_



not modelled 99.9 35 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
55d2shpa2



not modelled 99.9 29 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
56d2shpa3



not modelled 99.9 34 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
57d1fhsa_



not modelled 99.9 29 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
58c1x6cA_



not modelled 99.9 35 PDB header:signaling protein
Chain: A: PDB Molecule:tyrosine-protein phosphatase, non-receptor type
PDBTitle: solution structures of the sh2 domain of human protein-2 tyrosine phosphatase shp-1
59d2izva2



not modelled 99.9 27 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
60c2eobA_



not modelled 99.9 29 PDB header:hydrolase
Chain: A: PDB Molecule:1-phosphatidylinositol-4,5-bisphosphate
PDBTitle: solution structure of the second sh2 domain from rat plc2 gamma-2
61c2ekxA_



not modelled 99.9 25 PDB header:signaling protein
Chain: A: PDB Molecule:cytoplasmic tyrosine-protein kinase bmx;
PDBTitle: solution structure of the human bmx sh2 domain
62c2dlzA_



not modelled 99.9 24 PDB header:signaling protein
Chain: A: PDB Molecule:protein vav-2;
PDBTitle: solution structure of the sh2 domain of human protein vav-2
63c2crhA_



not modelled 99.9 19 PDB header:signaling protein
Chain: A: PDB Molecule:vav proto-oncogene;
PDBTitle: solution structure of the sh2 domain of human proto-2 oncogene protein vav1
64c2hdxB_



not modelled 99.9 28 PDB header:signaling protein
Chain: B: PDB Molecule:sh2-b ph domain containing signaling mediator 1
PDBTitle: crystal structure of the src homology-2 domain of sh2-b in2 complex with jak2 ptyr813 phosphopeptide
65c3ps5A_



not modelled 99.9 29 PDB header:hydrolase, signaling protein
Chain: A: PDB Molecule:tyrosine-protein phosphatase non-receptor type 6;
PDBTitle: crystal structure of the full-length human protein tyrosine2 phosphatase shp-1
66d1pica_



not modelled 99.9 33 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
67d2eyva1



not modelled 99.9 38 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
68d3c7ia1



not modelled 99.9 32 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
69c3gqiB_



not modelled 99.9 27 PDB header:transferase/transferase inhibitor
Chain: B: PDB Molecule:phospholipase c-gamma-1;
PDBTitle: crystal structure of activated receptor tyrosine kinase in complex2 with substrates
70c2c9wA_



not modelled 99.9 29 PDB header:transcription regulation
Chain: A: PDB Molecule:suppressor of cytokine signaling 2;
PDBTitle: crystal structure of socs-2 in complex with elongin-b and2 elongin-c at 1.9a resolution
71c2lctA_



not modelled 99.9 23 PDB header:signaling protein
Chain: A: PDB Molecule:proto-oncogene vav;
PDBTitle: solution structure of the vav1 sh2 domain complexed with a syk-derived2 doubly phosphorylated peptide
72d1ayaa_



not modelled 99.9 27 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
73c2vifA_



not modelled 99.9 27 PDB header:signaling protein
Chain: A: PDB Molecule:suppressor of cytokine signalling 6;
PDBTitle: crystal structure of socs6 sh2 domain in complex with a c-kit2 phosphopeptide
74c3mazA_



not modelled 99.9 20 PDB header:signaling protein
Chain: A: PDB Molecule:signal-transducing adaptor protein 1;
PDBTitle: crystal structure of the human brdg1/stap-1 sh2 domain in complex with2 the ntal ptyr136 peptide
75d2cs0a1



not modelled 99.9 35 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
76d1qada_



not modelled 99.9 35 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
77d2fcia1



not modelled 99.9 27 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
78d1r1qa_



not modelled 99.9 38 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
79d1jyra_



not modelled 99.9 34 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
80c2hmhA_



not modelled 99.9 27 PDB header:cytokine regulator
Chain: A: PDB Molecule:suppressor of cytokine signaling 3;
PDBTitle: crystal structure of socs3 in complex with gp130(ptyr757)2 phosphopeptide.
81c2izvA_



not modelled 99.9 26 PDB header:transcription
Chain: A: PDB Molecule:suppressor of cytokine signaling 4;
PDBTitle: crystal structure of socs-4 in complex with elongin-b and2 elongin-c at 2.55a resolution
82c2ci8A_



not modelled 99.9 29 PDB header:translation
Chain: A: PDB Molecule:cytoplasmic protein nck1;
PDBTitle: sh2 domain of human nck1 adaptor protein - uncomplexed
83d2c9wa2



not modelled 99.9 28 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
84d1fu6a_



not modelled 99.9 27 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
85c1rqqC_



not modelled 99.9 33 PDB header:transferase/signaling protein
Chain: C: PDB Molecule:adaptor protein aps;
PDBTitle: crystal structure of the insulin receptor kinase in complex2 with the sh2 domain of aps
86d1mila_



not modelled 99.9 31 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
87c2dcrA_



not modelled 99.9 25 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fes/fps;
PDBTitle: fully automated solution structure determination of the fes2 sh2 domain
88d1rpya_



not modelled 99.9 30 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
89c2kk6A_



not modelled 99.8 32 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fer;
PDBTitle: solution structure of sh2 domain of proto-oncogene tyrosine-2 protein kinase fer from homo sapiens, northeast structural3 genomics consortium (nesg) target hr3461d
90d1xa6a2



not modelled 99.8 32 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
91c3qwyA_



not modelled 99.8 24 PDB header:signaling protein
Chain: A: PDB Molecule:cell death abnormality protein 2;
PDBTitle: ced-2
92c2dvjA_



not modelled 99.8 30 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog,
PDBTitle: phosphorylated crk-ii
93c3gxxB_



not modelled 99.8 20 PDB header:transcription
Chain: B: PDB Molecule:transcription elongation factor spt6;
PDBTitle: structure of the sh2 domain of the candida glabrata2 transcription elongation factor spt6, crystal form b
94c3qwxX_



not modelled 99.8 24 PDB header:signaling protein
Chain: X: PDB Molecule:cell death abnormality protein 2;
PDBTitle: ced-2 1-174
95c2eyzA_



not modelled 99.8 31 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform ii
96c2cr4A_



not modelled 99.8 23 PDB header:signaling protein
Chain: A: PDB Molecule:sh3 domain-binding protein 2;
PDBTitle: solution structure of the sh2 domain of human sh3bp2 protein
97c2eyyA_



not modelled 99.8 30 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform i
98c2dx0B_



not modelled 99.8 41 PDB header:hydrolase
Chain: B: PDB Molecule:phospholipase c, gamma 2;
PDBTitle: crystal structure of the n-terminal sh2 domain of mouse2 phospholipase c-gamma 2
99c3or8A_



not modelled 99.7 24 PDB header:transcription
Chain: A: PDB Molecule:transcription elongation factor spt6;
PDBTitle: a tandem sh2 domain in transcription elongation factor spt6
100c1griA_



not modelled 99.7 27 PDB header:signal transduction adaptor
Chain: A: PDB Molecule:growth factor bound protein 2;
PDBTitle: grb2
101c2xp1A_



not modelled 99.6 20 PDB header:transcription
Chain: A: PDB Molecule:spt6;
PDBTitle: structure of the tandem sh2 domains from antonospora locustae2 transcription elongation factor spt6
102c2yt6A_



99.6 35 PDB header:cell cycle
Chain: A: PDB Molecule:adult male urinary bladder cdna, riken full-
PDBTitle: solution structure of the sh3_1 domain of yamaguchi sarcoma2 viral (v-yes) oncogene homolog 1
103d1uura3



not modelled 99.6 21 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
104c1xa6A_



not modelled 99.6 41 PDB header:signaling protein
Chain: A: PDB Molecule:beta2-chimaerin;
PDBTitle: crystal structure of the human beta2-chimaerin
105d1bf5a3



not modelled 99.5 20 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
106c3cblA_



not modelled 99.4 35 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fes/fps;
PDBTitle: crystal structure of human feline sarcoma viral oncogene homologue (v-2 fes) in complex with staurosporine and a consensus peptide
107c2cudA_



not modelled 99.4 28 PDB header:signaling protein
Chain: A: PDB Molecule:src-like-adapter;
PDBTitle: solution structure of the sh3 domain of the human src-like2 adopter protein (slap)
108c2jxbA_



not modelled 99.4 20 PDB header:signaling protein complex
Chain: A: PDB Molecule:t-cell surface glycoprotein cd3 epsilon chain,
PDBTitle: structure of cd3epsilon-nck2 first sh3 domain complex
109d1bg1a3



not modelled 99.4 18 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
110c2oi3A_



not modelled 99.3 26 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase hck;
PDBTitle: nmr structure analysis of the hematopoetic cell kinase sh32 domain complexed with an artificial high affinity ligand3 (pd1)
111c1mv3A_



not modelled 99.3 15 PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:myc box dependent interacting protein 1;
PDBTitle: nmr structure of the tumor suppressor bin1: alternative2 splicing in melanoma and interaction with c-myc
112c2rqrA_



not modelled 99.3 19 PDB header:protein binding
Chain: A: PDB Molecule:engulfment and cell motility protein 1, linker, dedicator
PDBTitle: the solution structure of human dock2 sh3 domain - elmo1 peptide2 chimera complex
113c1x6gA_



not modelled 99.2 16 PDB header:signaling protein
Chain: A: PDB Molecule:megakaryocyte-associated tyrosine-protein kinase;
PDBTitle: solution structures of the sh3 domain of human2 megakaryocyte-associated tyrosine-protein kinase.
114c2yupA_



not modelled 99.2 23 PDB header:cell adhesion
Chain: A: PDB Molecule:vinexin;
PDBTitle: solution structure of the second sh3 domain of human vinexin
115d1lcka1



not modelled 99.2 31 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
116c1x6bA_



not modelled 99.2 9 PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine exchange factor (gef) 16;
PDBTitle: solution structures of the sh3 domain of human rho guanine2 exchange factor (gef) 16
117d1awja_



not modelled 99.2 22 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
118d2iima1



not modelled 99.2 32 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
119d1udla_



not modelled 99.1 20 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
120c2fpeB_



not modelled 99.1 20 PDB header:signaling protein
Chain: B: PDB Molecule:c-jun-amino-terminal kinase interacting protein
PDBTitle: conserved dimerization of the ib1 src-homology 3 domain

Binding site prediction 

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