Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	Q	K	K	S	I	Y	V	A	Y	T	G	G	T	I	G	M	Q	R	S	E	Q	G	Y	I	P	V	S	G	H	L	Q	R	Q	L	A	L	M	P	E	F	H	R	P	E	M	P	D	F	T	I	H	E	Y	T	P	L	M	D	S
Secondary structure
SS confidence
Disorder		?	?	?	?															?	?	?	?	?	?			?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		S	D	M	T	P	E	D	W	Q	H	I	A	E	D	I	K	A	H	Y	D	D	Y	D	G	F	V	I	L	H	G	T	D	T	M	A	Y	T	A	S	A	L	S	F	M	L	E	N	L	G	K	P	V	I	V	T	G	S	Q	I	P
Secondary structure
SS confidence
Disorder																																																													?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		L	A	E	L	R	S	D	G	Q	I	N	L	L	N	A	L	Y	V	A	A	N	Y	P	I	N	E	V	T	L	F	F	N	N	R	L	Y	R	G	N	R	T	T	K	A	H	A	D	G	F	D	A	F	A	S	P	N	L	P	P	L
Secondary structure
SS confidence
Disorder		?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		L	E	A	G	I	H	I	R	R	L	N	T	P	P	A	P	H	G	E	G	E	L	I	V	H	P	I	T	P	Q	P	I	G	V	V	T	I	Y	P	G	I	S	A	D	V	V	R	N	F	L	R	Q	P	V	K	A	L	I	L	R
Secondary structure
SS confidence
Disorder															?		?	?		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		S	Y	G	V	G	N	A	P	Q	N	K	A	F	L	Q	E	L	Q	E	A	S	D	R	G	I	V	V	V	N	L	T	Q	C	M	S	G	K	V	N	M	G	G	Y	A	T	G	N	A	L	A	H	A	G	V	I	G	G	A	D	M
Secondary structure
SS confidence
Disorder																																								?					?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.
Sequence		T	V	E	A	T	L	T	K	L	H	Y	L	L	S	Q	E	L	D	T	E	T	I	R	K	A	M	S	Q	N	L	R	G	E	L	T	P	D	D
Secondary structure
SS confidence
Disorder																																		?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2ocd chain A domain 1 Region: 2 - 335 Aligned: 326 Modelled: 332 Confidence: 100.0% Identity: 69% Fold: Glutaminase/Asparaginase Superfamily: Glutaminase/Asparaginase Family: Glutaminase/Asparaginase Phyre2 PDB 2d6f chain A Region: 2 - 336 Aligned: 328 Modelled: 335 Confidence: 100.0% Identity: 31% PDB header:ligase/rna Chain: A: PDB Molecule:glutamyl-trna(gln) amidotransferase subunit d; PDBTitle: crystal structure of glu-trna(gln) amidotransferase in the2 complex with trna(gln) Phyre2 PDB 1zq1 chain B Region: 3 - 336 Aligned: 328 Modelled: 334 Confidence: 100.0% Identity: 30% PDB header:lyase Chain: B: PDB Molecule:glutamyl-trna(gln) amidotransferase subunit d; PDBTitle: structure of gatde trna-dependent amidotransferase from2 pyrococcus abyssi Phyre2 PDB 1zq1 chain A domain 2 Region: 2 - 336 Aligned: 330 Modelled: 334 Confidence: 100.0% Identity: 30% Fold: Glutaminase/Asparaginase Superfamily: Glutaminase/Asparaginase Family: Glutaminase/Asparaginase Phyre2 PDB 1wnf chain A Region: 5 - 335 Aligned: 322 Modelled: 331 Confidence: 100.0% Identity: 36% PDB header:hydrolase Chain: A: PDB Molecule:l-asparaginase; PDBTitle: crystal structure of ph0066 from pyrococcus horikoshii Phyre2 PDB 2d6f chain A domain 2 Region: 2 - 337 Aligned: 330 Modelled: 336 Confidence: 100.0% Identity: 30% Fold: Glutaminase/Asparaginase Superfamily: Glutaminase/Asparaginase Family: Glutaminase/Asparaginase Phyre2 PDB 1nns chain A Region: 4 - 328 Aligned: 316 Modelled: 321 Confidence: 100.0% Identity: 25% Fold: Glutaminase/Asparaginase Superfamily: Glutaminase/Asparaginase Family: Glutaminase/Asparaginase Phyre2 PDB 1wsa chain A Region: 3 - 328 Aligned: 311 Modelled: 326 Confidence: 100.0% Identity: 24% Fold: Glutaminase/Asparaginase Superfamily: Glutaminase/Asparaginase Family: Glutaminase/Asparaginase Phyre2 PDB 2wlt chain A Region: 4 - 328 Aligned: 315 Modelled: 325 Confidence: 100.0% Identity: 24% PDB header:hydrolase Chain: A: PDB Molecule:l-asparaginase; PDBTitle: the crystal structure of helicobacter pylori l-asparaginase2 at 1.4 a resolution Phyre2 PDB 1agx chain A Region: 3 - 328 Aligned: 316 Modelled: 326 Confidence: 100.0% Identity: 20% Fold: Glutaminase/Asparaginase Superfamily: Glutaminase/Asparaginase Family: Glutaminase/Asparaginase Phyre2 PDB 1o7j chain A Region: 4 - 328 Aligned: 311 Modelled: 317 Confidence: 100.0% Identity: 20% Fold: Glutaminase/Asparaginase Superfamily: Glutaminase/Asparaginase Family: Glutaminase/Asparaginase Phyre2 PDB 4pga chain A Region: 2 - 328 Aligned: 318 Modelled: 327 Confidence: 100.0% Identity: 20% Fold: Glutaminase/Asparaginase Superfamily: Glutaminase/Asparaginase Family: Glutaminase/Asparaginase Phyre2 PDB 3nxk chain E Region: 3 - 328 Aligned: 306 Modelled: 326 Confidence: 100.0% Identity: 23% PDB header:hydrolase Chain: E: PDB Molecule:cytoplasmic l-asparaginase; PDBTitle: crystal structure of probable cytoplasmic l-asparaginase from2 campylobacter jejuni Phyre2 PDB 1uz5 chain A Region: 2 - 96 Aligned: 83 Modelled: 95 Confidence: 91.0% Identity: 22% PDB header:molybdopterin biosynthesis Chain: A: PDB Molecule:402aa long hypothetical molybdopterin PDBTitle: the crystal structure of molybdopterin biosynthesis moea2 protein from pyrococcus horikosii Phyre2 PDB 1gtz chain A Region: 1 - 113 Aligned: 99 Modelled: 113 Confidence: 90.2% Identity: 18% Fold: Flavodoxin-like Superfamily: Type II 3-dehydroquinate dehydratase Family: Type II 3-dehydroquinate dehydratase Phyre2 PDB 2nqq chain A Region: 2 - 91 Aligned: 78 Modelled: 90 Confidence: 86.8% Identity: 17% PDB header:biosynthetic protein Chain: A: PDB Molecule:molybdopterin biosynthesis protein moea; PDBTitle: moea r137q Phyre2 PDB 1uz5 chain A domain 3 Region: 4 - 101 Aligned: 86 Modelled: 98 Confidence: 86.3% Identity: 21% Fold: Molybdenum cofactor biosynthesis proteins Superfamily: Molybdenum cofactor biosynthesis proteins Family: MoeA central domain-like Phyre2 PDB 1gqo chain A Region: 4 - 113 Aligned: 96 Modelled: 108 Confidence: 83.4% Identity: 14% Fold: Flavodoxin-like Superfamily: Type II 3-dehydroquinate dehydratase Family: Type II 3-dehydroquinate dehydratase Phyre2 PDB 2rjo chain A Region: 224 - 291 Aligned: 64 Modelled: 68 Confidence: 81.2% Identity: 17% PDB header:signaling protein Chain: A: PDB Molecule:twin-arginine translocation pathway signal protein; PDBTitle: crystal structure of twin-arginine translocation pathway signal2 protein from burkholderia phytofirmans Phyre2 PDB 2q62 chain A Region: 1 - 160 Aligned: 140 Modelled: 148 Confidence: 79.0% Identity: 12% PDB header:flavoprotein Chain: A: PDB Molecule:arsh; PDBTitle: crystal structure of arsh from sinorhizobium meliloti Phyre2 1 d2ocda1 2 c2d6fA_ 3 c1zq1B_ 4 d1zq1a2 5 c1wnfA_ 6 d2d6fa2 7 d1nnsa_ 8 d1wsaa_ 9 c2wltA_ 10 d1agxa_ 11 d1o7ja_ 12 d4pgaa_ 13 c3nxkE_ 14 c1uz5A_ 15 d1gtza_ 16 c2nqqA_ 17 d1uz5a3 18 d1gqoa_ 19 c2rjoA_ 20 c2q62A_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d2ocda1 100.0 69 Fold:Glutaminase/Asparaginase Superfamily:Glutaminase/Asparaginase Family:Glutaminase/Asparaginase 2 c2d6fA_ 100.0 31 PDB header:ligase/rna Chain: A: PDB Molecule:glutamyl-trna(gln) amidotransferase subunit d; PDBTitle: crystal structure of glu-trna(gln) amidotransferase in the2 complex with trna(gln) 3 c1zq1B_ 100.0 30 PDB header:lyase Chain: B: PDB Molecule:glutamyl-trna(gln) amidotransferase subunit d; PDBTitle: structure of gatde trna-dependent amidotransferase from2 pyrococcus abyssi 4 d1zq1a2 100.0 30 Fold:Glutaminase/Asparaginase Superfamily:Glutaminase/Asparaginase Family:Glutaminase/Asparaginase 5 c1wnfA_ 100.0 36 PDB header:hydrolase Chain: A: PDB Molecule:l-asparaginase; PDBTitle: crystal structure of ph0066 from pyrococcus horikoshii 6 d2d6fa2 100.0 30 Fold:Glutaminase/Asparaginase Superfamily:Glutaminase/Asparaginase Family:Glutaminase/Asparaginase 7 d1nnsa_ 100.0 25 Fold:Glutaminase/Asparaginase Superfamily:Glutaminase/Asparaginase Family:Glutaminase/Asparaginase 8 d1wsaa_ 100.0 24 Fold:Glutaminase/Asparaginase Superfamily:Glutaminase/Asparaginase Family:Glutaminase/Asparaginase 9 c2wltA_ 100.0 24 PDB header:hydrolase Chain: A: PDB Molecule:l-asparaginase; PDBTitle: the crystal structure of helicobacter pylori l-asparaginase2 at 1.4 a resolution 10 d1agxa_ 100.0 20 Fold:Glutaminase/Asparaginase Superfamily:Glutaminase/Asparaginase Family:Glutaminase/Asparaginase 11 d1o7ja_ 100.0 20 Fold:Glutaminase/Asparaginase Superfamily:Glutaminase/Asparaginase Family:Glutaminase/Asparaginase 12 d4pgaa_ 100.0 20 Fold:Glutaminase/Asparaginase Superfamily:Glutaminase/Asparaginase Family:Glutaminase/Asparaginase 13 c3nxkE_ 100.0 23 PDB header:hydrolase Chain: E: PDB Molecule:cytoplasmic l-asparaginase; PDBTitle: crystal structure of probable cytoplasmic l-asparaginase from2 campylobacter jejuni 14 c1uz5A_ 91.0 22 PDB header:molybdopterin biosynthesis Chain: A: PDB Molecule:402aa long hypothetical molybdopterin PDBTitle: the crystal structure of molybdopterin biosynthesis moea2 protein from pyrococcus horikosii 15 d1gtza_ 90.2 18 Fold:Flavodoxin-like Superfamily:Type II 3-dehydroquinate dehydratase Family:Type II 3-dehydroquinate dehydratase 16 c2nqqA_ 86.8 17 PDB header:biosynthetic protein Chain: A: PDB Molecule:molybdopterin biosynthesis protein moea; PDBTitle: moea r137q 17 d1uz5a3 86.3 21 Fold:Molybdenum cofactor biosynthesis proteins Superfamily:Molybdenum cofactor biosynthesis proteins Family:MoeA central domain-like 18 d1gqoa_ 83.4 14 Fold:Flavodoxin-like Superfamily:Type II 3-dehydroquinate dehydratase Family:Type II 3-dehydroquinate dehydratase 19 c2rjoA_ 81.2 17 PDB header:signaling protein Chain: A: PDB Molecule:twin-arginine translocation pathway signal protein; PDBTitle: crystal structure of twin-arginine translocation pathway signal2 protein from burkholderia phytofirmans 20 c2q62A_ 79.0 12 PDB header:flavoprotein Chain: A: PDB Molecule:arsh; PDBTitle: crystal structure of arsh from sinorhizobium meliloti 21 d2ftsa3 not modelled 76.6 11 Fold:Molybdenum cofactor biosynthesis proteins Superfamily:Molybdenum cofactor biosynthesis proteins Family:MoeA central domain-like 22 d2nqra3 not modelled 74.7 16 Fold:Molybdenum cofactor biosynthesis proteins Superfamily:Molybdenum cofactor biosynthesis proteins Family:MoeA central domain-like 23 c2pr7A_ not modelled 74.5 19 PDB header:hydrolase Chain: A: PDB Molecule:haloacid dehalogenase/epoxide hydrolase family; PDBTitle: crystal structure of uncharacterized protein (np_599989.1) from2 corynebacterium glutamicum atcc 13032 kitasato at 1.44 a resolution 24 c3s81A_ not modelled 73.6 15 PDB header:isomerase Chain: A: PDB Molecule:putative aspartate racemase; PDBTitle: crystal structure of putative aspartate racemase from salmonella2 typhimurium 25 d1wu2a3 not modelled 72.8 20 Fold:Molybdenum cofactor biosynthesis proteins Superfamily:Molybdenum cofactor biosynthesis proteins Family:MoeA central domain-like 26 c1powA_ not modelled 72.2 13 PDB header:oxidoreductase(oxygen as acceptor) Chain: A: PDB Molecule:pyruvate oxidase; PDBTitle: the refined structures of a stabilized mutant and of wild-type2 pyruvate oxidase from lactobacillus plantarum 27 d1goxa_ not modelled 71.3 21 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 28 c3d54D_ not modelled 70.9 25 PDB header:ligase Chain: D: PDB Molecule:phosphoribosylformylglycinamidine synthase 1; PDBTitle: stucture of purlqs from thermotoga maritima 29 d1tuba1 not modelled 70.1 13 Fold:Tubulin nucleotide-binding domain-like Superfamily:Tubulin nucleotide-binding domain-like Family:Tubulin, GTPase domain 30 c2fu3A_ not modelled 68.1 9 PDB header:biosynthetic protein/structural protein Chain: A: PDB Molecule:gephyrin; PDBTitle: crystal structure of gephyrin e-domain 31 c3ffsC_ not modelled 67.3 5 PDB header:oxidoreductase Chain: C: PDB Molecule:inosine-5-monophosphate dehydrogenase; PDBTitle: the crystal structure of cryptosporidium parvum inosine-5'-2 monophosphate dehydrogenase 32 c3o8nA_ not modelled 67.2 16 PDB header:transferase Chain: A: PDB Molecule:6-phosphofructokinase, muscle type; PDBTitle: structure of phosphofructokinase from rabbit skeletal muscle 33 d2ioja1 not modelled 66.7 32 Fold:MurF and HprK N-domain-like Superfamily:HprK N-terminal domain-like Family:DRTGG domain 34 d1h05a_ not modelled 66.2 24 Fold:Flavodoxin-like Superfamily:Type II 3-dehydroquinate dehydratase Family:Type II 3-dehydroquinate dehydratase 35 d1tb3a1 not modelled 65.6 14 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 36 c1wu2B_ not modelled 65.3 18 PDB header:structural genomics,biosynthetic protein Chain: B: PDB Molecule:molybdopterin biosynthesis moea protein; PDBTitle: crystal structure of molybdopterin biosynthesis moea2 protein from pyrococcus horikoshii ot3 37 d1uqra_ not modelled 64.2 18 Fold:Flavodoxin-like Superfamily:Type II 3-dehydroquinate dehydratase Family:Type II 3-dehydroquinate dehydratase 38 c3n8kG_ not modelled 63.0 24 PDB header:lyase Chain: G: PDB Molecule:3-dehydroquinate dehydratase; PDBTitle: type ii dehydroquinase from mycobacterium tuberculosis complexed with2 citrazinic acid 39 c2cdh1_ not modelled 62.0 20 PDB header:transferase Chain: 1: PDB Molecule:enoyl reductase; PDBTitle: architecture of the thermomyces lanuginosus fungal fatty2 acid synthase at 5 angstrom resolution. 40 c2z6jB_ not modelled 61.6 12 PDB header:oxidoreductase Chain: B: PDB Molecule:trans-2-enoyl-acp reductase ii; PDBTitle: crystal structure of s. pneumoniae enoyl-acyl carrier2 protein reductase (fabk) in complex with an inhibitor 41 d1dxya2 not modelled 61.5 18 Fold:Flavodoxin-like Superfamily:Formate/glycerate dehydrogenase catalytic domain-like Family:Formate/glycerate dehydrogenases, substrate-binding domain 42 d1s1ma1 not modelled 60.8 13 Fold:Flavodoxin-like Superfamily:Class I glutamine amidotransferase-like Family:Class I glutamine amidotransferases (GAT) 43 c2hmcA_ not modelled 60.0 13 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: the crystal structure of dihydrodipicolinate synthase dapa from2 agrobacterium tumefaciens 44 d1q7ra_ not modelled 57.0 18 Fold:Flavodoxin-like Superfamily:Class I glutamine amidotransferase-like Family:Class I glutamine amidotransferases (GAT) 45 c1jcnA_ not modelled 56.4 16 PDB header:oxidoreductase Chain: A: PDB Molecule:inosine monophosphate dehydrogenase i; PDBTitle: binary complex of human type-i inosine monophosphate dehydrogenase2 with 6-cl-imp 46 c3o1hB_ not modelled 55.6 11 PDB header:signaling protein Chain: B: PDB Molecule:periplasmic protein tort; PDBTitle: crystal structure of the tors sensor domain - tort complex in the2 presence of tmao 47 d1fuia2 not modelled 55.6 9 Fold:FucI/AraA N-terminal and middle domains Superfamily:FucI/AraA N-terminal and middle domains Family:L-fucose isomerase, N-terminal and second domains 48 d1ka9h_ not modelled 55.0 18 Fold:Flavodoxin-like Superfamily:Class I glutamine amidotransferase-like Family:Class I glutamine amidotransferases (GAT) 49 c2zskA_ not modelled 54.8 15 PDB header:unknown function Chain: A: PDB Molecule:226aa long hypothetical aspartate racemase; PDBTitle: crystal structure of ph1733, an aspartate racemase2 homologue, from pyrococcus horikoshii ot3 50 c3brsA_ not modelled 54.2 13 PDB header:transport protein Chain: A: PDB Molecule:periplasmic binding protein/laci transcriptional regulator; PDBTitle: crystal structure of sugar transporter from clostridium2 phytofermentans 51 c2dgdD_ not modelled 53.6 12 PDB header:lyase Chain: D: PDB Molecule:223aa long hypothetical arylmalonate decarboxylase; PDBTitle: crystal structure of st0656, a function unknown protein from2 sulfolobus tokodaii 52 c3mc3A_ not modelled 53.0 17 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:dsre/dsrf-like family protein; PDBTitle: crystal structure of dsre/dsrf-like family protein (np_342589.1) from2 sulfolobus solfataricus at 1.49 a resolution 53 c2e77B_ not modelled 52.4 9 PDB header:oxidoreductase Chain: B: PDB Molecule:lactate oxidase; PDBTitle: crystal structure of l-lactate oxidase with pyruvate complex 54 d1ccwa_ not modelled 52.2 17 Fold:Flavodoxin-like Superfamily:Cobalamin (vitamin B12)-binding domain Family:Cobalamin (vitamin B12)-binding domain 55 d1xi8a3 not modelled 52.0 18 Fold:Molybdenum cofactor biosynthesis proteins Superfamily:Molybdenum cofactor biosynthesis proteins Family:MoeA central domain-like 56 d1jlja_ not modelled 51.6 18 Fold:Molybdenum cofactor biosynthesis proteins Superfamily:Molybdenum cofactor biosynthesis proteins Family:MogA-like 57 d1i1qb_ not modelled 51.4 14 Fold:Flavodoxin-like Superfamily:Class I glutamine amidotransferase-like Family:Class I glutamine amidotransferases (GAT) 58 c3bo9B_ not modelled 51.3 18 PDB header:oxidoreductase Chain: B: PDB Molecule:putative nitroalkan dioxygenase; PDBTitle: crystal structure of putative nitroalkan dioxygenase (tm0800) from2 thermotoga maritima at 2.71 a resolution 59 c2rduA_ not modelled 50.9 16 PDB header:oxidoreductase Chain: A: PDB Molecule:hydroxyacid oxidase 1; PDBTitle: crystal structure of human glycolate oxidase in complex with2 glyoxylate 60 c3lloA_ not modelled 50.5 18 PDB header:motor protein Chain: A: PDB Molecule:prestin; PDBTitle: crystal structure of the stas domain of motor protein prestin (anion2 transporter slc26a5) 61 c1jscA_ not modelled 50.4 22 PDB header:lyase Chain: A: PDB Molecule:acetohydroxy-acid synthase; PDBTitle: crystal structure of the catalytic subunit of yeast2 acetohydroxyacid synthase: a target for herbicidal3 inhibitors 62 d2nv0a1 not modelled 50.1 25 Fold:Flavodoxin-like Superfamily:Class I glutamine amidotransferase-like Family:Class I glutamine amidotransferases (GAT) 63 c3lwzC_ not modelled 50.0 14 PDB header:lyase Chain: C: PDB Molecule:3-dehydroquinate dehydratase; PDBTitle: 1.65 angstrom resolution crystal structure of type ii 3-2 dehydroquinate dehydratase (aroq) from yersinia pestis 64 d2csua3 not modelled 49.8 15 Fold:Flavodoxin-like Superfamily:Succinyl-CoA synthetase domains Family:Succinyl-CoA synthetase domains 65 c2qs0A_ not modelled 49.7 25 PDB header:biosynthetic protein Chain: A: PDB Molecule:quinolinate synthetase a; PDBTitle: quinolinate synthase from pyrococcus furiosus 66 d1wl8a1 not modelled 49.5 14 Fold:Flavodoxin-like Superfamily:Class I glutamine amidotransferase-like Family:Class I glutamine amidotransferases (GAT) 67 c2xecD_ not modelled 49.4 16 PDB header:isomerase Chain: D: PDB Molecule:putative maleate isomerase; PDBTitle: nocardia farcinica maleate cis-trans isomerase bound to2 tris 68 d1vcoa1 not modelled 49.4 20 Fold:Flavodoxin-like Superfamily:Class I glutamine amidotransferase-like Family:Class I glutamine amidotransferases (GAT) 69 d2c4va1 not modelled 49.0 33 Fold:Flavodoxin-like Superfamily:Type II 3-dehydroquinate dehydratase Family:Type II 3-dehydroquinate dehydratase 70 c3khjE_ not modelled 48.9 15 PDB header:oxidoreductase Chain: E: PDB Molecule:inosine-5-monophosphate dehydrogenase; PDBTitle: c. parvum inosine monophosphate dehydrogenase bound by inhibitor c64 71 d2csua1 not modelled 48.8 12 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:CoA-binding domain 72 c3nurA_ not modelled 48.5 7 PDB header:hydrolase Chain: A: PDB Molecule:amidohydrolase; PDBTitle: crystal structure of a putative amidohydrolase from staphylococcus2 aureus 73 c2opiB_ not modelled 48.5 9 PDB header:lyase Chain: B: PDB Molecule:l-fuculose-1-phosphate aldolase; PDBTitle: crystal structure of l-fuculose-1-phosphate aldolase from bacteroides2 thetaiotaomicron 74 d1t3ta2 not modelled 48.0 18 Fold:Flavodoxin-like Superfamily:Class I glutamine amidotransferase-like Family:Class I glutamine amidotransferases (GAT) 75 c2r94B_ not modelled 48.0 17 PDB header:lyase Chain: B: PDB Molecule:2-keto-3-deoxy-(6-phospho-)gluconate aldolase; PDBTitle: crystal structure of kd(p)ga from t.tenax 76 d2btoa1 not modelled 47.9 15 Fold:Tubulin nucleotide-binding domain-like Superfamily:Tubulin nucleotide-binding domain-like Family:Tubulin, GTPase domain 77 d2hbva1 not modelled 47.1 8 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:PP1699/LP2961-like 78 c2iexA_ not modelled 47.0 18 PDB header:lyase Chain: A: PDB Molecule:dihydroxynapthoic acid synthetase; PDBTitle: crystal structure of dihydroxynapthoic acid synthetase (gk2873) from2 geobacillus kaustophilus hta426 79 d1j4aa2 not modelled 46.7 18 Fold:Flavodoxin-like Superfamily:Formate/glycerate dehydrogenase catalytic domain-like Family:Formate/glycerate dehydrogenases, substrate-binding domain 80 d1q8fa_ not modelled 46.5 20 Fold:Nucleoside hydrolase Superfamily:Nucleoside hydrolase Family:Nucleoside hydrolase 81 d1r61a_ not modelled 45.4 10 Fold:The "swivelling" beta/beta/alpha domain Superfamily:Putative cyclase Family:Putative cyclase 82 d1gpma2 not modelled 44.4 16 Fold:Flavodoxin-like Superfamily:Class I glutamine amidotransferase-like Family:Class I glutamine amidotransferases (GAT) 83 c3ojcD_ not modelled 43.8 9 PDB header:isomerase Chain: D: PDB Molecule:putative aspartate/glutamate racemase; PDBTitle: crystal structure of a putative asp/glu racemase from yersinia pestis 84 c2uygF_ not modelled 43.2 19 PDB header:lyase Chain: F: PDB Molecule:3-dehydroquinate dehydratase; PDBTitle: crystallogaphic structure of the typeii 3-dehydroquinase2 from thermus thermophilus 85 d1uuya_ not modelled 43.1 13 Fold:Molybdenum cofactor biosynthesis proteins Superfamily:Molybdenum cofactor biosynthesis proteins Family:MogA-like 86 d1y5ea1 not modelled 42.0 22 Fold:Molybdenum cofactor biosynthesis proteins Superfamily:Molybdenum cofactor biosynthesis proteins Family:MogA-like 87 c2obnA_ not modelled 41.8 24 PDB header:unknown function Chain: A: PDB Molecule:hypothetical protein; PDBTitle: crystal structure of a duf1611 family protein (ava_3511) from anabaena2 variabilis atcc 29413 at 2.30 a resolution 88 c2fzvC_ not modelled 41.5 11 PDB header:structural genomics, unknown function Chain: C: PDB Molecule:putative arsenical resistance protein; PDBTitle: crystal structure of an apo form of a flavin-binding protein from2 shigella flexneri 89 c2vlbC_ not modelled 41.4 14 PDB header:lyase Chain: C: PDB Molecule:arylmalonate decarboxylase; PDBTitle: structure of unliganded arylmalonate decarboxylase 90 c1ozhD_ not modelled 41.0 16 PDB header:lyase Chain: D: PDB Molecule:acetolactate synthase, catabolic; PDBTitle: the crystal structure of klebsiella pneumoniae acetolactate2 synthase with enzyme-bound cofactor and with an unusual3 intermediate. 91 c2issF_ not modelled 40.9 27 PDB header:lyase, transferase Chain: F: PDB Molecule:glutamine amidotransferase subunit pdxt; PDBTitle: structure of the plp synthase holoenzyme from thermotoga maritima 92 d2dlda2 not modelled 40.8 25 Fold:Flavodoxin-like Superfamily:Formate/glycerate dehydrogenase catalytic domain-like Family:Formate/glycerate dehydrogenases, substrate-binding domain 93 c3l7nA_ not modelled 39.6 18 PDB header:transferase Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: crystal structure of smu.1228c 94 c2a7rD_ not modelled 39.3 10 PDB header:oxidoreductase Chain: D: PDB Molecule:gmp reductase 2; PDBTitle: crystal structure of human guanosine monophosphate2 reductase 2 (gmpr2) 95 d1p4ca_ not modelled 38.9 16 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 96 d1wzua1 not modelled 38.9 35 Fold:NadA-like Superfamily:NadA-like Family:NadA-like 97 d1q6za1 not modelled 38.4 12 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Pyruvate oxidase and decarboxylase, middle domain 98 c3kipU_ not modelled 38.1 24 PDB header:lyase Chain: U: PDB Molecule:3-dehydroquinase, type ii; PDBTitle: crystal structure of type-ii 3-dehydroquinase from c. albicans 99 c3g1wB_ not modelled 37.8 13 PDB header:transport protein Chain: B: PDB Molecule:sugar abc transporter; PDBTitle: crystal structure of sugar abc transporter (sugar-binding protein)2 from bacillus halodurans 100 c2a7nA_ not modelled 37.5 16 PDB header:oxidoreductase Chain: A: PDB Molecule:l(+)-mandelate dehydrogenase; PDBTitle: crystal structure of the g81a mutant of the active chimera of (s)-2 mandelate dehydrogenase 101 d1jcna1 not modelled 37.2 16 Fold:TIM beta/alpha-barrel Superfamily:Inosine monophosphate dehydrogenase (IMPDH) Family:Inosine monophosphate dehydrogenase (IMPDH) 102 c1brwB_ not modelled 37.2 17 PDB header:transferase Chain: B: PDB Molecule:protein (pyrimidine nucleoside phosphorylase); PDBTitle: the crystal structure of pyrimidine nucleoside2 phosphorylase in a closed conformation 103 d1mx3a2 not modelled 37.1 18 Fold:Flavodoxin-like Superfamily:Formate/glycerate dehydrogenase catalytic domain-like Family:Formate/glycerate dehydrogenases, substrate-binding domain 104 c2htmB_ not modelled 37.0 16 PDB header:biosynthetic protein Chain: B: PDB Molecule:thiazole biosynthesis protein thig; PDBTitle: crystal structure of ttha0676 from thermus thermophilus hb8 105 d1k9vf_ not modelled 36.9 23 Fold:Flavodoxin-like Superfamily:Class I glutamine amidotransferase-like Family:Class I glutamine amidotransferases (GAT) 106 d1vmea1 not modelled 36.2 17 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:Flavodoxin-related 107 d1qwga_ not modelled 36.2 25 Fold:TIM beta/alpha-barrel Superfamily:(2r)-phospho-3-sulfolactate synthase ComA Family:(2r)-phospho-3-sulfolactate synthase ComA 108 d1eepa_ not modelled 36.1 9 Fold:TIM beta/alpha-barrel Superfamily:Inosine monophosphate dehydrogenase (IMPDH) Family:Inosine monophosphate dehydrogenase (IMPDH) 109 c2qneA_ not modelled 36.1 21 PDB header:transferase Chain: A: PDB Molecule:putative methyltransferase; PDBTitle: crystal structure of putative methyltransferase (zp_00558420.1) from2 desulfitobacterium hafniense y51 at 2.30 a resolution 110 d1ls1a2 not modelled 36.0 22 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Nitrogenase iron protein-like 111 c1keeH_ not modelled 35.5 17 PDB header:ligase Chain: H: PDB Molecule:carbamoyl-phosphate synthetase small chain; PDBTitle: inactivation of the amidotransferase activity of carbamoyl phosphate2 synthetase by the antibiotic acivicin 112 c3gdwA_ not modelled 35.5 22 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:sigma-54 interaction domain protein; PDBTitle: crystal structure of sigma-54 interaction domain protein from2 enterococcus faecalis 113 d1tubb1 not modelled 35.2 17 Fold:Tubulin nucleotide-binding domain-like Superfamily:Tubulin nucleotide-binding domain-like Family:Tubulin, GTPase domain 114 c3bezC_ not modelled 35.2 28 PDB header:hydrolase Chain: C: PDB Molecule:protease 4; PDBTitle: crystal structure of escherichia coli signal peptide peptidase (sppa),2 semet crystals 115 d1jr1a1 not modelled 34.9 18 Fold:TIM beta/alpha-barrel Superfamily:Inosine monophosphate dehydrogenase (IMPDH) Family:Inosine monophosphate dehydrogenase (IMPDH) 116 c2ax3A_ not modelled 34.6 19 PDB header:transferase Chain: A: PDB Molecule:hypothetical protein tm0922; PDBTitle: crystal structure of a putative carbohydrate kinase (tm0922) from2 thermotoga maritima msb8 at 2.25 a resolution 117 d1im5a_ not modelled 34.0 16 Fold:Isochorismatase-like hydrolases Superfamily:Isochorismatase-like hydrolases Family:Isochorismatase-like hydrolases 118 c3k2qA_ not modelled 33.6 17 PDB header:transferase Chain: A: PDB Molecule:pyrophosphate-dependent phosphofructokinase; PDBTitle: crystal structure of pyrophosphate-dependent2 phosphofructokinase from marinobacter aquaeolei, northeast3 structural genomics consortium target mqr88 119 c3ij6A_ not modelled 33.6 13 PDB header:hydrolase Chain: A: PDB Molecule:uncharacterized metal-dependent hydrolase; PDBTitle: crystal structure of an uncharacterized metal-dependent2 hydrolase from lactobacillus acidophilus 120 d1ezra_ not modelled 33.5 12 Fold:Nucleoside hydrolase Superfamily:Nucleoside hydrolase Family:Nucleoside hydrolase

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0