Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	L	D	P	N	L	L	R	N	E	P	D	A	V	A	E	K	L	A	R	R	G	F	K	L	D	V	D	K	L	G	A	L	E	E	R	R	K	V	L	Q	V	K	T	E	N	L	Q	A	E	R	N	S	R	S	K	S	I	G	Q
Secondary structure
SS confidence
Disorder		?	?	?																		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		A	K	A	R	G	E	D	I	E	P	L	R	L	E	V	N	K	L	G	E	E	L	D	A	A	K	A	E	L	D	A	L	Q	A	E	I	R	D	I	A	L	T	I	P	N	L	P	A	D	E	V	P	V	G	K	D	E	N	D	N
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		V	E	V	S	R	W	G	T	P	R	E	F	D	F	E	V	R	D	H	V	T	L	G	E	M	H	S	G	L	D	F	A	A	A	V	K	L	T	G	S	R	F	V	V	M	K	G	Q	I	A	R	M	H	R	A	L	S	Q	F	M
Secondary structure
SS confidence
Disorder										?		?																									?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		L	D	L	H	T	E	Q	H	G	Y	S	E	N	Y	V	P	Y	L	V	N	Q	D	T	L	Y	G	T	G	Q	L	P	K	F	A	G	D	L	F	H	T	R	P	L	E	E	E	A	D	T	S	N	Y	A	L	I	P	T	A	E	V
Secondary structure
SS confidence
Disorder																					?									?	?	?	?											?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		P	L	T	N	L	V	R	G	E	I	I	D	E	D	D	L	P	I	K	M	T	A	H	T	P	C	F	R	S	E	A	G	S	Y	G	R	D	T	R	G	L	I	R	M	H	Q	F	D	K	V	E	M	V	Q	I	V	R	P	E	D
Secondary structure
SS confidence
Disorder																																		?		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		S	M	A	A	L	E	E	M	T	G	H	A	E	K	V	L	Q	L	L	G	L	P	Y	R	K	I	I	L	C	T	G	D	M	G	F	G	A	C	K	T	Y	D	L	E	V	W	I	P	A	Q	N	T	Y	R	E	I	S	S	C	S
Secondary structure
SS confidence
Disorder																																?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		N	V	W	D	F	Q	A	R	R	M	Q	A	R	C	R	S	K	S	D	K	K	T	R	L	V	H	T	L	N	G	S	G	L	A	V	G	R	T	L	V	A	V	M	E	N	Y	Q	Q	A	D	G	R	I	E	V	P	E	V	L	R
Secondary structure
SS confidence
Disorder																	?	?		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430
Sequence		P	Y	M	N	G	L	E	Y	I	G
Secondary structure
SS confidence
Disorder					?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3lss chain A Region: 1 - 430 Aligned: 421 Modelled: 430 Confidence: 100.0% Identity: 34% PDB header:ligase Chain: A: PDB Molecule:seryl-trna synthetase; PDBTitle: trypanosoma brucei seryl-trna synthetase in complex with atp Phyre2 PDB 2dq0 chain A Region: 1 - 430 Aligned: 422 Modelled: 430 Confidence: 100.0% Identity: 38% PDB header:ligase Chain: A: PDB Molecule:seryl-trna synthetase; PDBTitle: crystal structure of seryl-trna synthetase from pyrococcus2 horikoshii complexed with a seryl-adenylate analog Phyre2 PDB 1wle chain B Region: 1 - 430 Aligned: 422 Modelled: 426 Confidence: 100.0% Identity: 28% PDB header:ligase Chain: B: PDB Molecule:seryl-trna synthetase; PDBTitle: crystal structure of mammalian mitochondrial seryl-trna2 synthetase complexed with seryl-adenylate Phyre2 PDB 2dq3 chain A Region: 1 - 430 Aligned: 421 Modelled: 429 Confidence: 100.0% Identity: 56% PDB header:ligase Chain: A: PDB Molecule:seryl-trna synthetase; PDBTitle: crystal structure of aq_298 Phyre2 PDB 1sry chain B Region: 1 - 430 Aligned: 416 Modelled: 430 Confidence: 100.0% Identity: 38% PDB header:ligase(synthetase) Chain: B: PDB Molecule:seryl-trna synthetase; PDBTitle: refined crystal structure of the seryl-trna synthetase from2 thermus thermophilus at 2.5 angstroms resolution Phyre2 PDB 3qo8 chain A Region: 1 - 429 Aligned: 414 Modelled: 429 Confidence: 100.0% Identity: 31% PDB header:ligase Chain: A: PDB Molecule:seryl-trna synthetase, cytoplasmic; PDBTitle: crystal structure of seryl-trna synthetase from candida albicans Phyre2 PDB 3err chain B Region: 3 - 429 Aligned: 415 Modelled: 427 Confidence: 100.0% Identity: 36% PDB header:ligase Chain: B: PDB Molecule:fusion protein of microtubule binding domain from PDBTitle: microtubule binding domain from mouse cytoplasmic dynein as2 a fusion with seryl-trna synthetase Phyre2 PDB 1set chain A domain 2 Region: 115 - 428 Aligned: 304 Modelled: 314 Confidence: 100.0% Identity: 39% Fold: Class II aaRS and biotin synthetases Superfamily: Class II aaRS and biotin synthetases Family: Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain Phyre2 PDB 2cj9 chain A Region: 99 - 426 Aligned: 310 Modelled: 328 Confidence: 100.0% Identity: 20% PDB header:ligase Chain: A: PDB Molecule:seryl-trna synthetase; PDBTitle: crystal structure of methanosarcina barkeri seryl-trna2 synthetase complexed with an analog of seryladenylate Phyre2 PDB 1qf6 chain A domain 4 Region: 137 - 407 Aligned: 255 Modelled: 271 Confidence: 100.0% Identity: 17% Fold: Class II aaRS and biotin synthetases Superfamily: Class II aaRS and biotin synthetases Family: Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain Phyre2 PDB 1nyr chain A domain 4 Region: 138 - 402 Aligned: 254 Modelled: 265 Confidence: 100.0% Identity: 20% Fold: Class II aaRS and biotin synthetases Superfamily: Class II aaRS and biotin synthetases Family: Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain Phyre2 PDB 1nj8 chain A domain 3 Region: 139 - 409 Aligned: 258 Modelled: 271 Confidence: 100.0% Identity: 19% Fold: Class II aaRS and biotin synthetases Superfamily: Class II aaRS and biotin synthetases Family: Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain Phyre2 PDB 1nj1 chain A domain 3 Region: 139 - 409 Aligned: 257 Modelled: 271 Confidence: 100.0% Identity: 18% Fold: Class II aaRS and biotin synthetases Superfamily: Class II aaRS and biotin synthetases Family: Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain Phyre2 PDB 3mf2 chain B Region: 142 - 426 Aligned: 264 Modelled: 285 Confidence: 100.0% Identity: 19% PDB header:ligase Chain: B: PDB Molecule:bll0957 protein; PDBTitle: crystal structure of class ii aars homologue (bll0957) complexed with2 amp Phyre2 PDB 1hc7 chain A domain 2 Region: 139 - 409 Aligned: 248 Modelled: 271 Confidence: 100.0% Identity: 17% Fold: Class II aaRS and biotin synthetases Superfamily: Class II aaRS and biotin synthetases Family: Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain Phyre2 PDB 1nyq chain A Region: 109 - 422 Aligned: 296 Modelled: 314 Confidence: 100.0% Identity: 21% PDB header:ligase Chain: A: PDB Molecule:threonyl-trna synthetase 1; PDBTitle: structure of staphylococcus aureus threonyl-trna synthetase2 complexed with an analogue of threonyl adenylate Phyre2 PDB 3ial chain B Region: 139 - 422 Aligned: 270 Modelled: 284 Confidence: 100.0% Identity: 18% PDB header:ligase Chain: B: PDB Molecule:prolyl-trna synthetase; PDBTitle: giardia lamblia prolyl-trna synthetase in complex with prolyl-2 adenylate Phyre2 PDB 1qf6 chain A Region: 109 - 422 Aligned: 293 Modelled: 314 Confidence: 100.0% Identity: 16% PDB header:ligase/rna Chain: A: PDB Molecule:threonyl-trna synthetase; PDBTitle: structure of e. coli threonyl-trna synthetase complexed with its2 cognate trna Phyre2 PDB 1b76 chain A domain 2 Region: 140 - 421 Aligned: 275 Modelled: 280 Confidence: 100.0% Identity: 17% Fold: Class II aaRS and biotin synthetases Superfamily: Class II aaRS and biotin synthetases Family: Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain Phyre2 PDB 1ati chain A domain 2 Region: 140 - 421 Aligned: 275 Modelled: 282 Confidence: 100.0% Identity: 16% Fold: Class II aaRS and biotin synthetases Superfamily: Class II aaRS and biotin synthetases Family: Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain Phyre2 1 c3lssA_ 2 c2dq0A_ 3 c1wleB_ 4 c2dq3A_ 5 c1sryB_ 6 c3qo8A_ 7 c3errB_ 8 d1seta2 9 c2cj9A_ 10 d1qf6a4 11 d1nyra4 12 d1nj8a3 13 d1nj1a3 14 c3mf2B_ 15 d1hc7a2 16 c1nyqA_ 17 c3ialB_ 18 c1qf6A_ 19 d1b76a2 20 d1atia2 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3lssA_ 100.0 34 PDB header:ligase Chain: A: PDB Molecule:seryl-trna synthetase; PDBTitle: trypanosoma brucei seryl-trna synthetase in complex with atp 2 c2dq0A_ 100.0 38 PDB header:ligase Chain: A: PDB Molecule:seryl-trna synthetase; PDBTitle: crystal structure of seryl-trna synthetase from pyrococcus2 horikoshii complexed with a seryl-adenylate analog 3 c1wleB_ 100.0 28 PDB header:ligase Chain: B: PDB Molecule:seryl-trna synthetase; PDBTitle: crystal structure of mammalian mitochondrial seryl-trna2 synthetase complexed with seryl-adenylate 4 c2dq3A_ 100.0 56 PDB header:ligase Chain: A: PDB Molecule:seryl-trna synthetase; PDBTitle: crystal structure of aq_298 5 c1sryB_ 100.0 38 PDB header:ligase(synthetase) Chain: B: PDB Molecule:seryl-trna synthetase; PDBTitle: refined crystal structure of the seryl-trna synthetase from2 thermus thermophilus at 2.5 angstroms resolution 6 c3qo8A_ 100.0 31 PDB header:ligase Chain: A: PDB Molecule:seryl-trna synthetase, cytoplasmic; PDBTitle: crystal structure of seryl-trna synthetase from candida albicans 7 c3errB_ 100.0 36 PDB header:ligase Chain: B: PDB Molecule:fusion protein of microtubule binding domain from PDBTitle: microtubule binding domain from mouse cytoplasmic dynein as2 a fusion with seryl-trna synthetase 8 d1seta2 100.0 39 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 9 c2cj9A_ 100.0 20 PDB header:ligase Chain: A: PDB Molecule:seryl-trna synthetase; PDBTitle: crystal structure of methanosarcina barkeri seryl-trna2 synthetase complexed with an analog of seryladenylate 10 d1qf6a4 100.0 17 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 11 d1nyra4 100.0 20 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 12 d1nj8a3 100.0 19 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 13 d1nj1a3 100.0 18 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 14 c3mf2B_ 100.0 19 PDB header:ligase Chain: B: PDB Molecule:bll0957 protein; PDBTitle: crystal structure of class ii aars homologue (bll0957) complexed with2 amp 15 d1hc7a2 100.0 17 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 16 c1nyqA_ 100.0 21 PDB header:ligase Chain: A: PDB Molecule:threonyl-trna synthetase 1; PDBTitle: structure of staphylococcus aureus threonyl-trna synthetase2 complexed with an analogue of threonyl adenylate 17 c3ialB_ 100.0 18 PDB header:ligase Chain: B: PDB Molecule:prolyl-trna synthetase; PDBTitle: giardia lamblia prolyl-trna synthetase in complex with prolyl-2 adenylate 18 c1qf6A_ 100.0 16 PDB header:ligase/rna Chain: A: PDB Molecule:threonyl-trna synthetase; PDBTitle: structure of e. coli threonyl-trna synthetase complexed with its2 cognate trna 19 d1b76a2 100.0 17 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 20 d1atia2 100.0 16 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 21 c1nj8C_ not modelled 100.0 20 PDB header:ligase Chain: C: PDB Molecule:proline-trna synthetase; PDBTitle: crystal structure of prolyl-trna synthetase from2 methanocaldococcus janaschii 22 c1h4tD_ not modelled 100.0 17 PDB header:aminoacyl-trna synthetase Chain: D: PDB Molecule:prolyl-trna synthetase; PDBTitle: prolyl-trna synthetase from thermus thermophilus complexed2 with l-proline 23 c1nj2A_ not modelled 100.0 18 PDB header:ligase Chain: A: PDB Molecule:proline-trna synthetase; PDBTitle: crystal structure of prolyl-trna synthetase from methanothermobacter2 thermautotrophicus 24 c1fyfB_ not modelled 100.0 16 PDB header:ligase Chain: B: PDB Molecule:threonyl-trna synthetase; PDBTitle: crystal structure of a truncated form of threonyl-trna2 synthetase complexed with a seryl adenylate analog 25 c2j3mA_ not modelled 100.0 23 PDB header:ligase Chain: A: PDB Molecule:prolyl-trna synthetase; PDBTitle: prolyl-trna synthetase from enterococcus faecalis complexed2 with atp, manganese and prolinol 26 c2i4lC_ not modelled 100.0 19 PDB header:ligase Chain: C: PDB Molecule:proline-trna ligase; PDBTitle: rhodopseudomonas palustris prolyl-trna synthetase 27 c1ggmB_ not modelled 100.0 16 PDB header:ligase Chain: B: PDB Molecule:protein (glycyl-trna synthetase); PDBTitle: glycyl-trna synthetase from thermus thermophilus complexed with2 glycyl-adenylate 28 c1atiA_ not modelled 100.0 17 PDB header:protein biosynthesis Chain: A: PDB Molecule:glycyl-trna synthetase; PDBTitle: crystal structure of glycyl-trna synthetase from thermus thermophilus 29 c3a32A_ not modelled 100.0 17 PDB header:ligase Chain: A: PDB Molecule:probable threonyl-trna synthetase 1; PDBTitle: crystal structure of putative threonyl-trna synthetase2 thrrs-1 from aeropyrum pernix 30 c1g5hA_ not modelled 100.0 15 PDB header:dna binding protein Chain: A: PDB Molecule:mitochondrial dna polymerase accessory subunit; PDBTitle: crystal structure of the accessory subunit of murine mitochondrial2 polymerase gamma 31 d1g5ha2 not modelled 100.0 16 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 32 c2pmfA_ not modelled 100.0 22 PDB header:ligase Chain: A: PDB Molecule:glycyl-trna synthetase; PDBTitle: the crystal structure of a human glycyl-trna synthetase mutant 33 d2g4ca2 not modelled 100.0 12 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 34 c3ikmC_ not modelled 100.0 13 PDB header:transferase Chain: C: PDB Molecule:dna polymerase subunit gamma-2; PDBTitle: crystal structure of human mitochondrial dna polymerase2 holoenzyme 35 d1seta1 not modelled 99.9 30 Fold:Long alpha-hairpin Superfamily:tRNA-binding arm Family:Seryl-tRNA synthetase (SerRS) 36 c2el9B_ not modelled 99.8 13 PDB header:ligase Chain: B: PDB Molecule:histidyl-trna synthetase; PDBTitle: crystal structure of e.coli histidyl-trna synthetase2 complexed with a histidyl-adenylate analogue 37 c1adyA_ not modelled 99.8 20 PDB header:trna synthetase Chain: A: PDB Molecule:histidyl-trna synthetase; PDBTitle: histidyl-trna synthetase in complex with histidyl-adenylate 38 c3hriF_ not modelled 99.8 21 PDB header:ligase Chain: F: PDB Molecule:histidyl-trna synthetase; PDBTitle: histidyl-trna synthetase (apo) from trypanosoma brucei 39 c1qe0B_ not modelled 99.8 18 PDB header:ligase Chain: B: PDB Molecule:histidyl-trna synthetase; PDBTitle: crystal structure of apo s. aureus histidyl-trna synthetase 40 c1wu7A_ not modelled 99.8 15 PDB header:ligase Chain: A: PDB Molecule:histidyl-trna synthetase; PDBTitle: crystal structure of histidyl-trna synthetase from2 thermoplasma acidophilum 41 c3netB_ not modelled 99.7 18 PDB header:ligase Chain: B: PDB Molecule:histidyl-trna synthetase; PDBTitle: crystal structure of histidyl-trna synthetase from nostoc sp. pcc 7120 42 c3od1A_ not modelled 99.7 18 PDB header:transferase Chain: A: PDB Molecule:atp phosphoribosyltransferase regulatory subunit; PDBTitle: the crystal structure of an atp phosphoribosyltransferase regulatory2 subunit/histidyl-trna synthetase from bacillus halodurans c 43 c2zimA_ not modelled 99.6 21 PDB header:ligase Chain: A: PDB Molecule:pyrrolysyl-trna synthetase; PDBTitle: pyrrolysyl-trna synthetase bound to adenylated pyrrolysine and2 pyrophosphate 44 c2znjB_ not modelled 99.6 16 PDB header:ligase Chain: B: PDB Molecule:putative uncharacterized protein; PDBTitle: crystal structure of pyrrolysyl-trna synthetase from2 desulfitobacterium hafniense 45 d1kmma2 not modelled 99.5 13 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 46 d1wu7a2 not modelled 99.5 16 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 47 c1z7nB_ not modelled 99.3 18 PDB header:transferase Chain: B: PDB Molecule:atp phosphoribosyltransferase regulatory subunit; PDBTitle: atp phosphoribosyl transferase (hiszg atp-prtase) from2 lactococcus lactis with bound prpp substrate 48 d1h4vb2 not modelled 99.2 21 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 49 d1z7ma1 not modelled 99.1 18 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 50 c3racA_ not modelled 99.1 16 PDB header:ligase Chain: A: PDB Molecule:histidine-trna ligase; PDBTitle: crystal strucutre of histidine--trna ligase subunit from2 alicyclobacillus acidocaldarius subsp. acidocaldarius dsm 446. 51 c1b70A_ not modelled 99.1 15 PDB header:ligase Chain: A: PDB Molecule:phenylalanyl-trna synthetase; PDBTitle: phenylalanyl trna synthetase complexed with phenylalanine 52 c2du4B_ not modelled 99.1 16 PDB header:ligase/rna Chain: B: PDB Molecule:o-phosphoseryl-trna synthetase; PDBTitle: crystal structure of archaeoglobus fulgidus o-phosphoseryl-2 trna synthetase complexed with trnacys 53 c3l4gI_ not modelled 99.1 14 PDB header:ligase Chain: I: PDB Molecule:phenylalanyl-trna synthetase alpha chain; PDBTitle: crystal structure of homo sapiens cytoplasmic phenylalanyl-trna2 synthetase 54 d1jjca_ not modelled 99.1 15 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 55 c2du7C_ not modelled 98.9 15 PDB header:ligase Chain: C: PDB Molecule:o-phosphoseryl-trna synthetase; PDBTitle: crystal structure of methanococcus jannacshii o-phosphoseryl-trna2 synthetase 56 d1nnha_ not modelled 98.9 17 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 57 c2rhqA_ not modelled 98.7 14 PDB header:ligase Chain: A: PDB Molecule:phenylalanyl-trna synthetase alpha chain; PDBTitle: phers from staphylococcus haemolyticus- rational protein2 engineering and inhibitor studies 58 d1qe0a2 not modelled 98.7 21 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 59 d1e1oa2 not modelled 98.7 16 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 60 c3g1zB_ not modelled 98.7 14 PDB header:ligase Chain: B: PDB Molecule:putative lysyl-trna synthetase; PDBTitle: structure of idp01693/yjea, a potential t-rna synthetase from2 salmonella typhimurium 61 d1l0wa3 not modelled 98.6 22 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 62 d1c0aa3 not modelled 98.6 21 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 63 d1eova2 not modelled 98.6 18 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 64 c3pcoC_ not modelled 98.5 13 PDB header:ligase Chain: C: PDB Molecule:phenylalanyl-trna synthetase, alpha subunit; PDBTitle: crystal structure of e. coli phenylalanine-trna synthetase complexed2 with phenylalanine and amp 65 d1bbua2 not modelled 98.5 18 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 66 d1b8aa2 not modelled 98.5 22 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 67 c3e9hB_ not modelled 98.4 25 PDB header:ligase Chain: B: PDB Molecule:lysyl-trna synthetase; PDBTitle: lysyl-trna synthetase from bacillus stearothermophilus2 complexed with l-lysylsulfamoyl adenosine 68 c1e22A_ not modelled 98.3 20 PDB header:ligase Chain: A: PDB Molecule:lysyl-trna synthetase; PDBTitle: lysyl-trna synthetase (lysu) hexagonal form complexed with2 lysine and the non-hydrolysable atp analogue amp-pcp 69 c3bjuB_ not modelled 98.3 20 PDB header:ligase Chain: B: PDB Molecule:lysyl-trna synthetase; PDBTitle: crystal structure of tetrameric form of human lysyl-trna2 synthetase 70 c1efwA_ not modelled 98.2 20 PDB header:ligase/rna Chain: A: PDB Molecule:aspartyl-trna synthetase; PDBTitle: crystal structure of aspartyl-trna synthetase from thermus2 thermophilus complexed to trnaasp from escherichia coli 71 c1eqrC_ not modelled 98.2 18 PDB header:ligase Chain: C: PDB Molecule:aspartyl-trna synthetase; PDBTitle: crystal structure of free aspartyl-trna synthetase from2 escherichia coli 72 d1usya_ not modelled 98.2 15 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 73 c1x55A_ not modelled 98.1 26 PDB header:ligase Chain: A: PDB Molecule:asparaginyl-trna synthetase; PDBTitle: crystal structure of asparaginyl-trna synthetase from pyrococcus2 horikoshii complexed with asparaginyl-adenylate analogue 74 c3m4qA_ not modelled 98.1 18 PDB header:ligase Chain: A: PDB Molecule:asparaginyl-trna synthetase, putative; PDBTitle: entamoeba histolytica asparaginyl-trna synthetase (asnrs) 75 c2xgtB_ not modelled 98.0 23 PDB header:ligase Chain: B: PDB Molecule:asparaginyl-trna synthetase, cytoplasmic; PDBTitle: asparaginyl-trna synthetase from brugia malayi complexed2 with the sulphamoyl analogue of asparaginyl-adenylate 76 c1asyA_ not modelled 98.0 14 PDB header:complex (aminoacyl-trna synthase/trna) Chain: A: PDB Molecule:aspartyl-trna synthetase; PDBTitle: class ii aminoacyl transfer rna synthetases: crystal2 structure of yeast aspartyl-trna synthetase complexed with3 trna asp 77 c1b8aB_ not modelled 97.9 22 PDB header:ligase Chain: B: PDB Molecule:protein (aspartyl-trna synthetase); PDBTitle: aspartyl-trna synthetase 78 c1wydB_ not modelled 97.8 15 PDB header:ligase Chain: B: PDB Molecule:hypothetical aspartyl-trna synthetase; PDBTitle: crystal structure of aspartyl-trna synthetase from sulfolobus tokodaii 79 c3i7fA_ not modelled 97.1 18 PDB header:ligase Chain: A: PDB Molecule:aspartyl-trna synthetase; PDBTitle: aspartyl trna synthetase from entamoeba histolytica 80 c3l4gL_ not modelled 97.0 14 PDB header:ligase Chain: L: PDB Molecule:phenylalanyl-trna synthetase beta chain; PDBTitle: crystal structure of homo sapiens cytoplasmic phenylalanyl-trna2 synthetase 81 c3cmqA_ not modelled 97.0 15 PDB header:ligase Chain: A: PDB Molecule:phenylalanyl-trna synthetase, mitochondrial; PDBTitle: crystal structure of human mitochondrial phenylalanine trna2 synthetase 82 c3ig2B_ not modelled 97.0 11 PDB header:ligase Chain: B: PDB Molecule:phenylalanyl-trna synthetase beta chain; PDBTitle: the crystal structure of a putative phenylalanyl-trna synthetase2 (phers) beta chain domain from bacteroides fragilis to 2.1a 83 c3icaB_ not modelled 96.9 14 PDB header:ligase Chain: B: PDB Molecule:phenylalanyl-trna synthetase beta chain; PDBTitle: the crystal structure of the beta subunit of a phenylalanyl-trna2 synthetase from porphyromonas gingivalis w83 84 d1jjcb5 not modelled 95.0 13 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 85 c3hnwB_ not modelled 92.7 19 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of a basic coiled-coil protein of unknown function2 from eubacterium eligens atcc 27750 86 d1n9wa2 not modelled 91.5 21 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 87 c1deqO_ not modelled 90.9 12 PDB header: PDB COMPND: 88 c1ei3E_ not modelled 89.8 6 PDB header: PDB COMPND: 89 c2rhsB_ not modelled 89.7 10 PDB header:ligase Chain: B: PDB Molecule:phenylalanyl-trna synthetase beta chain; PDBTitle: phers from staphylococcus haemolyticus- rational protein2 engineering and inhibitor studies 90 c3ghgK_ not modelled 89.0 10 PDB header:blood clotting Chain: K: PDB Molecule:fibrinogen beta chain; PDBTitle: crystal structure of human fibrinogen 91 c2akwB_ not modelled 81.7 13 PDB header:ligase Chain: B: PDB Molecule:phenylalanyl-trna synthetase beta chain; PDBTitle: crystal structure of t.thermophilus phenylalanyl-trna synthetase2 complexed with p-cl-phenylalanine 92 c1n9wA_ not modelled 81.0 20 PDB header:biosynthetic protein Chain: A: PDB Molecule:aspartyl-trna synthetase 2; PDBTitle: crystal structure of the non-discriminating and archaeal-2 type aspartyl-trna synthetase from thermus thermophilus 93 c1deqF_ not modelled 80.9 15 PDB header: PDB COMPND: 94 c3ojaB_ not modelled 78.3 18 PDB header:protein binding Chain: B: PDB Molecule:anopheles plasmodium-responsive leucine-rich repeat protein PDBTitle: crystal structure of lrim1/apl1c complex 95 c3pcoD_ not modelled 77.2 14 PDB header:ligase Chain: D: PDB Molecule:phenylalanyl-trna synthetase, beta chain; PDBTitle: crystal structure of e. coli phenylalanine-trna synthetase complexed2 with phenylalanine and amp 96 c2ke4A_ not modelled 71.8 11 PDB header:membrane protein Chain: A: PDB Molecule:cdc42-interacting protein 4; PDBTitle: the nmr structure of the tc10 and cdc42 interacting domain2 of cip4 97 d2f4ma1 not modelled 71.1 22 Fold:Cysteine proteinases Superfamily:Cysteine proteinases Family:Transglutaminase core 98 c2zdiA_ not modelled 69.7 14 PDB header:chaperone Chain: A: PDB Molecule:prefoldin subunit beta; PDBTitle: crystal structure of prefoldin from pyrococcus horikoshii2 ot3 99 c3isrB_ not modelled 66.9 10 PDB header:hydrolase Chain: B: PDB Molecule:transglutaminase-like enzymes, putative cysteine protease; PDBTitle: the crystal structure of a putative cysteine protease from cytophaga2 hutchinsonii to 1.9a 100 d12asa_ not modelled 64.7 23 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 101 d2f23a1 not modelled 64.0 13 Fold:Long alpha-hairpin Superfamily:GreA transcript cleavage protein, N-terminal domain Family:GreA transcript cleavage protein, N-terminal domain 102 c3sjbC_ not modelled 63.1 18 PDB header:hydrolase/transport protein Chain: C: PDB Molecule:golgi to er traffic protein 1; PDBTitle: crystal structure of s. cerevisiae get3 in the open state in complex2 with get1 cytosolic domain 103 c1l8dB_ not modelled 57.7 17 PDB header:replication Chain: B: PDB Molecule:dna double-strand break repair rad50 atpase; PDBTitle: rad50 coiled-coil zn hook 104 c3sjaG_ not modelled 57.4 19 PDB header:hydrolase/transport protein Chain: G: PDB Molecule:golgi to er traffic protein 1; PDBTitle: crystal structure of s. cerevisiae get3 in the open state in complex2 with get1 cytosolic domain 105 c2gl2B_ not modelled 56.2 16 PDB header:cell adhesion Chain: B: PDB Molecule:adhesion a; PDBTitle: crystal structure of the tetra muntant (t66g,r67g,f68g,2 y69g) of bacterial adhesin fada 106 c3dtpA_ not modelled 54.1 14 PDB header:contractile protein Chain: A: PDB Molecule:myosin 2 heavy chain chimera of smooth and PDBTitle: tarantula heavy meromyosin obtained by flexible docking to2 tarantula muscle thick filament cryo-em 3d-map 107 d1grja1 not modelled 50.9 19 Fold:Long alpha-hairpin Superfamily:GreA transcript cleavage protein, N-terminal domain Family:GreA transcript cleavage protein, N-terminal domain 108 d1gqea_ not modelled 48.4 15 Fold:Release factor Superfamily:Release factor Family:Release factor 109 c3u59C_ not modelled 47.1 15 PDB header:contractile protein Chain: C: PDB Molecule:tropomyosin beta chain; PDBTitle: n-terminal 98-aa fragment of smooth muscle tropomyosin beta 110 d1fxka_ not modelled 45.5 12 Fold:Long alpha-hairpin Superfamily:Prefoldin Family:Prefoldin 111 c3hxxA_ not modelled 44.9 19 PDB header:ligase Chain: A: PDB Molecule:alanyl-trna synthetase; PDBTitle: crystal structure of catalytic fragment of e. coli alars in complex2 with amppcp 112 c1ik9B_ not modelled 42.2 18 PDB header:gene regulation/ligase Chain: B: PDB Molecule:dna repair protein xrcc4; PDBTitle: crystal structure of a xrcc4-dna ligase iv complex 113 c3a7pB_ not modelled 40.2 19 PDB header:protein transport Chain: B: PDB Molecule:autophagy protein 16; PDBTitle: the crystal structure of saccharomyces cerevisiae atg16 114 c3cwgA_ not modelled 38.6 13 PDB header:transcription Chain: A: PDB Molecule:signal transducer and activator of transcription PDBTitle: unphosphorylated mouse stat3 core fragment 115 c2y3aB_ not modelled 36.9 11 PDB header:transferase Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit beta; PDBTitle: crystal structure of p110beta in complex with icsh2 of p85beta and2 the drug gdc-0941 116 c3na7A_ not modelled 36.5 14 PDB header:gene regulation, chaperone Chain: A: PDB Molecule:hp0958; PDBTitle: 2.2 angstrom structure of the hp0958 protein from helicobacter pylori2 ccug 17874 117 c2p4vA_ not modelled 35.8 16 PDB header:transcription Chain: A: PDB Molecule:transcription elongation factor greb; PDBTitle: crystal structure of the transcript cleavage factor, greb2 at 2.6a resolution 118 c2etnA_ not modelled 33.7 14 PDB header:transcription Chain: A: PDB Molecule:anti-cleavage anti-grea transcription factor PDBTitle: crystal structure of thermus aquaticus gfh1 119 c2fxmB_ not modelled 33.3 19 PDB header:contractile protein Chain: B: PDB Molecule:myosin heavy chain, cardiac muscle beta isoform; PDBTitle: structure of the human beta-myosin s2 fragment 120 c1dipA_ not modelled 32.8 19 PDB header:acetylation Chain: A: PDB Molecule:delta-sleep-inducing peptide immunoreactive PDBTitle: the solution structure of porcine delta-sleep-inducing2 peptide immunoreactive peptide, nmr, 10 structures

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0