Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP66948
DateThu Jan 5 12:10:22 GMT 2012
Unique Job ID6b6413d4b4ecc346

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c3c37B_
Top template information
PDB header:hydrolase
Chain: B: PDB Molecule:peptidase, m48 family;
PDBTitle: x-ray structure of the putative zn-dependent peptidase q74d82 at the2 resolution 1.7 a. northeast structural genomics consortium target3 gsr143a
Confidence and coverage
Confidence:100.0% Coverage: 45%
219 residues ( 45% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
430 residues ( 88%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MFRQLKKNLVATLIAAMTIGQVAPAFADSADTLPDMGTSAGSTLSIGQEMQMGDYYVRQL
Secondary structure 
SS confidence 
Disorder  ?????
??
?
????
??
?
?
Disorder confidence 
 
   .........70.........80.........90.........100.........110.........120
Sequence  RGSAPLINDPLLTQYINSLGMRLVSHANSVKTPFHFFLINNDEINAFAFFGGNVVLHSAL
Secondary structure 
SS confidence 
Disorder 
????
Disorder confidence 
 
   .........130.........140.........150.........160.........170.........180
Sequence  FRYSDNESQLASVMAHEISHVTQRHLARAMEDQQRSAPLTWVGALGSILLAMASPQAGMA
Secondary structure 
SS confidence 
Disorder 
????????
Disorder confidence 
 
   .........190.........200.........210.........220.........230.........240
Sequence  ALTGTLAGTRQGMISFTQQNEQEADRIGIQVLQRSGFDPQAMPTFLEKLLDQARYSSRPP
Secondary structure 
SS confidence 
Disorder 
?
?
????????
Disorder confidence 
 
   .........250.........260.........270.........280.........290.........300
Sequence  EILLTHPLPESRLADARNRANQMRPMVVQSSEDFYLAKARTLGMYNSGRNQLTSDLLDEW
Secondary structure 
SS confidence 
Disorder 
??????
?
?
Disorder confidence 
 
   .........310.........320.........330.........340.........350.........360
Sequence  AKGNVRQQRAAQYGRALQAMEANKYDEARKTLQPLLAAEPGNAWYLDLATDIDLGQNKAN
Secondary structure 
SS confidence 
Disorder  ????????
???
?
Disorder confidence 
 
   .........370.........380.........390.........400.........410.........420
Sequence  EAINRLKNARDLRTNPVLQLNLANAYLQGGQPQEAANILNRYTFNNKDDSNGWDLLAQAE
Secondary structure 
SS confidence 
Disorder 
?
Disorder confidence 
 
   .........430.........440.........450.........460.........470.........480
Sequence  AALNNRDQELAARAEGYALAGRLDQAISLLSSASSQVKLGSLQQARYDARIDQLRQLQER
Secondary structure 
SS confidence 
Disorder 
???
???????
Disorder confidence 
 
   .......
Sequence  FKPYTKM
Secondary structure 
SS confidence 
Disorder 
????
Disorder confidence 
 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 3c37 chain B

3D model

Region: 40 - 283
Aligned: 219
Modelled: 244
Confidence: 100.0%
Identity: 30%
PDB header:hydrolase
Chain: B: PDB Molecule:peptidase, m48 family;
PDBTitle: x-ray structure of the putative zn-dependent peptidase q74d82 at the2 resolution 1.7 a. northeast structural genomics consortium target3 gsr143a

Phyre2

PDB 3pe3 chain D

3D model

Region: 304 - 479
Aligned: 176
Modelled: 176
Confidence: 99.8%
Identity: 17%
PDB header:transferase
Chain: D: PDB Molecule:udp-n-acetylglucosamine--peptide n-
PDBTitle: structure of human o-glcnac transferase and its complex with a peptide2 substrate

Phyre2

PDB 2xpi chain A

3D model

Region: 199 - 486
Aligned: 286
Modelled: 288
Confidence: 99.7%
Identity: 12%
PDB header:cell cycle
Chain: A: PDB Molecule:anaphase-promoting complex subunit cut9;
PDBTitle: crystal structure of apc/c hetero-tetramer cut9-hcn1

Phyre2

PDB 1xnf chain A

3D model

Region: 290 - 476
Aligned: 187
Modelled: 187
Confidence: 99.7%
Identity: 19%
Fold: alpha-alpha superhelix
Superfamily: TPR-like
Family: Tetratricopeptide repeat (TPR)

Phyre2

PDB 2y4t chain A

3D model

Region: 308 - 486
Aligned: 179
Modelled: 179
Confidence: 99.7%
Identity: 21%
PDB header:chaperone
Chain: A: PDB Molecule:dnaj homolog subfamily c member 3;
PDBTitle: crystal structure of the human co-chaperone p58(ipk)

Phyre2

PDB 1w3b chain A

3D model

Region: 313 - 486
Aligned: 174
Modelled: 174
Confidence: 99.7%
Identity: 18%
Fold: alpha-alpha superhelix
Superfamily: TPR-like
Family: Tetratricopeptide repeat (TPR)

Phyre2

PDB 3cvp chain A

3D model

Region: 302 - 486
Aligned: 184
Modelled: 185
Confidence: 99.7%
Identity: 21%
PDB header:transport protein
Chain: A: PDB Molecule:peroxisome targeting signal 1 receptor pex5;
PDBTitle: structure of peroxisomal targeting signal 1 (pts1) binding2 domain of trypanosoma brucei peroxin 5 (tbpex5)complexed3 to pts1 peptide (10-skl)

Phyre2

PDB 2vq2 chain A

3D model

Region: 309 - 467
Aligned: 159
Modelled: 159
Confidence: 99.7%
Identity: 17%
PDB header:structural protein
Chain: A: PDB Molecule:putative fimbrial biogenesis and twitching
PDBTitle: crystal structure of pilw, widely conserved type iv pilus2 biogenesis factor

Phyre2

PDB 3as5 chain A

3D model

Region: 305 - 460
Aligned: 156
Modelled: 156
Confidence: 99.7%
Identity: 17%
PDB header:protein binding
Chain: A: PDB Molecule:mama;
PDBTitle: mama amb-1 p212121

Phyre2

PDB 2r5s chain B

3D model

Region: 312 - 486
Aligned: 158
Modelled: 158
Confidence: 99.7%
Identity: 15%
PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:uncharacterized protein vp0806;
PDBTitle: the crystal structure of a domain of protein vp0806 (unknown function)2 from vibrio parahaemolyticus rimd 2210633

Phyre2

PDB 2q7f chain A

3D model

Region: 292 - 463
Aligned: 170
Modelled: 172
Confidence: 99.6%
Identity: 16%
PDB header:protein binding
Chain: A: PDB Molecule:yrrb protein;
PDBTitle: crystal structure of yrrb: a tpr protein with an unusual peptide-2 binding site

Phyre2

PDB 3ieg chain B

3D model

Region: 308 - 486
Aligned: 179
Modelled: 178
Confidence: 99.6%
Identity: 21%
PDB header:chaperone
Chain: B: PDB Molecule:dnaj homolog subfamily c member 3;
PDBTitle: crystal structure of p58(ipk) tpr domain at 2.5 a

Phyre2

PDB 1fch chain B

3D model

Region: 302 - 486
Aligned: 185
Modelled: 185
Confidence: 99.6%
Identity: 14%
PDB header:signaling protein
Chain: B: PDB Molecule:peroxisomal targeting signal 1 receptor;
PDBTitle: crystal structure of the pts1 complexed to the tpr region2 of human pex5

Phyre2

PDB 2ho1 chain B

3D model

Region: 307 - 487
Aligned: 181
Modelled: 181
Confidence: 99.6%
Identity: 12%
PDB header:protein binding
Chain: B: PDB Molecule:type 4 fimbrial biogenesis protein pilf;
PDBTitle: functional characterization of pseudomonas aeruginosa pilf

Phyre2

PDB 3hym chain B

3D model

Region: 307 - 486
Aligned: 180
Modelled: 180
Confidence: 99.6%
Identity: 21%
PDB header:cell cycle, ligase
Chain: B: PDB Molecule:cell division cycle protein 16 homolog;
PDBTitle: insights into anaphase promoting complex tpr subdomain2 assembly from a cdc26-apc6 structure

Phyre2

PDB 2hyz chain A

3D model

Region: 309 - 460
Aligned: 135
Modelled: 135
Confidence: 99.6%
Identity: 24%
PDB header:de novo protein
Chain: A: PDB Molecule:synthetic consensus tpr protein;
PDBTitle: crystal structure of an 8 repeat consensus tpr superhelix2 (orthorombic crystal form)

Phyre2

PDB 3mv3 chain B

3D model

Region: 266 - 485
Aligned: 206
Modelled: 220
Confidence: 99.6%
Identity: 14%
PDB header:protein transport
Chain: B: PDB Molecule:coatomer subunit epsilon;
PDBTitle: crystal structure of a-cop in complex with e-cop

Phyre2

PDB 2h6f chain A domain 1

3D model

Region: 240 - 487
Aligned: 240
Modelled: 248
Confidence: 99.6%
Identity: 7%
Fold: alpha-alpha superhelix
Superfamily: Protein prenylyltransferase
Family: Protein prenylyltransferase

Phyre2

PDB 1tno chain I

3D model

Region: 240 - 487
Aligned: 240
Modelled: 248
Confidence: 99.6%
Identity: 8%
PDB header:transferase
Chain: I: PDB Molecule:geranylgeranyltransferase type i alpha subunit;
PDBTitle: rat protein geranylgeranyltransferase type-i complexed with2 a ggpp analog and a kkksktkcvim peptide derived from k-3 ras4b

Phyre2

PDB 3urz chain B

3D model

Region: 308 - 477
Aligned: 169
Modelled: 169
Confidence: 99.6%
Identity: 14%
PDB header:protein binding
Chain: B: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of a hypothetical protein (bacova_03105) from2 bacteroides ovatus atcc 8483 at 2.19 a resolution

Phyre2
1
c3c37B_
2
c3pe3D_
3
c2xpiA_
4
d1xnfa_
5
c2y4tA_
6
d1w3ba_
7
c3cvpA_
8
c2vq2A_
9
c3as5A_
10
c2r5sB_
11
c2q7fA_
12
c3iegB_
13
c1fchB_
14
c2ho1B_
15
c3hymB_
16
c2hyzA_
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c3mv3B_
18
d2h6fa1
19
c1tnoI_
20
c3urzB_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c3c37B_
100.0 30 PDB header:hydrolase
Chain: B: PDB Molecule:peptidase, m48 family;
PDBTitle: x-ray structure of the putative zn-dependent peptidase q74d82 at the2 resolution 1.7 a. northeast structural genomics consortium target3 gsr143a
2c3pe3D_
99.8 17 PDB header:transferase
Chain: D: PDB Molecule:udp-n-acetylglucosamine--peptide n-
PDBTitle: structure of human o-glcnac transferase and its complex with a peptide2 substrate
3c2xpiA_
99.7 12 PDB header:cell cycle
Chain: A: PDB Molecule:anaphase-promoting complex subunit cut9;
PDBTitle: crystal structure of apc/c hetero-tetramer cut9-hcn1
4d1xnfa_
99.7 19 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
5c2y4tA_
99.7 21 PDB header:chaperone
Chain: A: PDB Molecule:dnaj homolog subfamily c member 3;
PDBTitle: crystal structure of the human co-chaperone p58(ipk)
6d1w3ba_
99.7 18 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
7c3cvpA_
99.7 21 PDB header:transport protein
Chain: A: PDB Molecule:peroxisome targeting signal 1 receptor pex5;
PDBTitle: structure of peroxisomal targeting signal 1 (pts1) binding2 domain of trypanosoma brucei peroxin 5 (tbpex5)complexed3 to pts1 peptide (10-skl)
8c2vq2A_
99.7 17 PDB header:structural protein
Chain: A: PDB Molecule:putative fimbrial biogenesis and twitching
PDBTitle: crystal structure of pilw, widely conserved type iv pilus2 biogenesis factor
9c3as5A_
99.7 17 PDB header:protein binding
Chain: A: PDB Molecule:mama;
PDBTitle: mama amb-1 p212121
10c2r5sB_
99.7 15 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:uncharacterized protein vp0806;
PDBTitle: the crystal structure of a domain of protein vp0806 (unknown function)2 from vibrio parahaemolyticus rimd 2210633
11c2q7fA_
99.6 16 PDB header:protein binding
Chain: A: PDB Molecule:yrrb protein;
PDBTitle: crystal structure of yrrb: a tpr protein with an unusual peptide-2 binding site
12c3iegB_
99.6 21 PDB header:chaperone
Chain: B: PDB Molecule:dnaj homolog subfamily c member 3;
PDBTitle: crystal structure of p58(ipk) tpr domain at 2.5 a
13c1fchB_
99.6 14 PDB header:signaling protein
Chain: B: PDB Molecule:peroxisomal targeting signal 1 receptor;
PDBTitle: crystal structure of the pts1 complexed to the tpr region2 of human pex5
14c2ho1B_
99.6 12 PDB header:protein binding
Chain: B: PDB Molecule:type 4 fimbrial biogenesis protein pilf;
PDBTitle: functional characterization of pseudomonas aeruginosa pilf
15c3hymB_
99.6 21 PDB header:cell cycle, ligase
Chain: B: PDB Molecule:cell division cycle protein 16 homolog;
PDBTitle: insights into anaphase promoting complex tpr subdomain2 assembly from a cdc26-apc6 structure
16c2hyzA_
99.6 24 PDB header:de novo protein
Chain: A: PDB Molecule:synthetic consensus tpr protein;
PDBTitle: crystal structure of an 8 repeat consensus tpr superhelix2 (orthorombic crystal form)
17c3mv3B_
99.6 14 PDB header:protein transport
Chain: B: PDB Molecule:coatomer subunit epsilon;
PDBTitle: crystal structure of a-cop in complex with e-cop
18d2h6fa1
99.6 7 Fold:alpha-alpha superhelix
Superfamily:Protein prenylyltransferase
Family:Protein prenylyltransferase
19c1tnoI_
99.6 8 PDB header:transferase
Chain: I: PDB Molecule:geranylgeranyltransferase type i alpha subunit;
PDBTitle: rat protein geranylgeranyltransferase type-i complexed with2 a ggpp analog and a kkksktkcvim peptide derived from k-3 ras4b
20c3urzB_
99.6 14 PDB header:protein binding
Chain: B: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of a hypothetical protein (bacova_03105) from2 bacteroides ovatus atcc 8483 at 2.19 a resolution
21d1dcea1
not modelled 99.6 11 Fold:alpha-alpha superhelix
Superfamily:Protein prenylyltransferase
Family:Protein prenylyltransferase
22c3q75A_
not modelled 99.6 7 PDB header:transferase
Chain: A: PDB Molecule:farnesyltransferase alpha subunit;
PDBTitle: cryptococcus neoformans protein farnesyltransferase in complex with2 fpt-ii and tkcvvm peptide
23c2pl2A_
not modelled 99.6 22 PDB header:protein binding
Chain: A: PDB Molecule:hypothetical conserved protein ttc0263;
PDBTitle: crystal structure of ttc0263: a thermophilic tpr protein in thermus2 thermophilus hb27
24d2c2la1
not modelled 99.6 12 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
25d1fcha_
not modelled 99.6 13 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
26d1d8da_
not modelled 99.5 6 Fold:alpha-alpha superhelix
Superfamily:Protein prenylyltransferase
Family:Protein prenylyltransferase
27c3cqbB_
not modelled 99.5 21 PDB header:hydrolase
Chain: B: PDB Molecule:probable protease htpx homolog;
PDBTitle: crystal structure of heat shock protein htpx domain from vibrio2 parahaemolyticus rimd 2210633
28c2gw1A_
not modelled 99.5 29 PDB header:protein transport
Chain: A: PDB Molecule:mitochondrial precursor proteins import receptor;
PDBTitle: crystal structure of the yeast tom70
29c3qdnA_
not modelled 99.5 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative thioredoxin protein;
PDBTitle: putative thioredoxin protein from salmonella typhimurium
30c2xcbA_
not modelled 99.5 22 PDB header:protein binding
Chain: A: PDB Molecule:regulatory protein pcrh;
PDBTitle: crystal structure of pcrh in complex with the chaperone2 binding region of popd
31c2e2eA_
not modelled 99.5 22 PDB header:lyase
Chain: A: PDB Molecule:formate-dependent nitrite reductase complex nrfg subunit;
PDBTitle: tpr domain of nrfg mediates the complex formation between heme lyase2 and formate-dependent nitrite reductase in escherichia coli o157:h7
32c1wao4_
not modelled 99.5 15 PDB header:hydrolase
Chain: 4: PDB Molecule:serine/threonine protein phosphatase 5;
PDBTitle: pp5 structure
33d1hh8a_
not modelled 99.5 11 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
34c2vyiA_
not modelled 99.5 13 PDB header:chaperone
Chain: A: PDB Molecule:sgta protein;
PDBTitle: crystal structure of the tpr domain of human sgt
35c3fp4A_
not modelled 99.5 14 PDB header:transport protein
Chain: A: PDB Molecule:tpr repeat-containing protein yhr117w;
PDBTitle: crystal structure of tom71 complexed with ssa1 c-terminal2 fragment
36c3mkrA_
not modelled 99.4 16 PDB header:transport protein
Chain: A: PDB Molecule:coatomer subunit epsilon;
PDBTitle: crystal structure of yeast alpha/epsilon-cop subcomplex of the copi2 vesicular coat
37d1qsaa1
not modelled 99.4 15 Fold:alpha-alpha superhelix
Superfamily:Bacterial muramidases
Family:Bacterial muramidases
38d1elwa_
not modelled 99.4 14 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
39d1a17a_
not modelled 99.4 15 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
40c3gyzB_
not modelled 99.4 14 PDB header:chaperone
Chain: B: PDB Molecule:chaperone protein ipgc;
PDBTitle: crystal structure of ipgc from shigella flexneri
41c3gw4B_
not modelled 99.4 15 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of uncharacterized protein from deinococcus2 radiodurans. northeast structural genomics consortium target drr162b.
42d1zu2a1
not modelled 99.4 12 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
43c3draA_
not modelled 99.4 6 PDB header:transferase
Chain: A: PDB Molecule:protein
PDBTitle: candida albicans protein geranylgeranyltransferase-i2 complexed with ggpp
44c3sz7A_
not modelled 99.4 13 PDB header:chaperone regulator
Chain: A: PDB Molecule:hsc70 cochaperone (sgt);
PDBTitle: crystal structure of the sgt2 tpr domain from aspergillus fumigatus
45c3ly8A_
not modelled 99.4 12 PDB header:signaling protein
Chain: A: PDB Molecule:transcriptional activator cadc;
PDBTitle: crystal structure of mutant d471e of the periplasmic domain of cadc
46d2ooea1
not modelled 99.3 15 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:HAT/Suf repeat
47d1hz4a_
not modelled 99.3 13 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Transcription factor MalT domain III
48d2buga1
not modelled 99.3 16 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
49c2c2lD_
not modelled 99.3 11 PDB header:chaperone
Chain: D: PDB Molecule:carboxy terminus of hsp70-interacting protein;
PDBTitle: crystal structure of the chip u-box e3 ubiquitin ligase
50c1ihgA_
not modelled 99.3 17 PDB header:isomerase
Chain: A: PDB Molecule:cyclophilin 40;
PDBTitle: bovine cyclophilin 40, monoclinic form
51d1p5qa1
not modelled 99.3 17 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
52c1kt0A_
not modelled 99.3 14 PDB header:isomerase
Chain: A: PDB Molecule:51 kda fk506-binding protein;
PDBTitle: structure of the large fkbp-like protein, fkbp51, involved in steroid2 receptor complexes
53c2ifuA_
not modelled 99.2 16 PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:gamma-snap;
PDBTitle: crystal structure of a gamma-snap from danio rerio
54c2yhcA_
not modelled 99.2 11 PDB header:membrane protein
Chain: A: PDB Molecule:upf0169 lipoprotein yfio;
PDBTitle: structure of bamd from e. coli
55d1kt1a1
not modelled 99.2 14 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
56d1iyga_
not modelled 99.2 9 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
57c3q49B_
not modelled 99.2 15 PDB header:ligase/chaperone
Chain: B: PDB Molecule:stip1 homology and u box-containing protein 1;
PDBTitle: crystal structure of the tpr domain of chip complexed with hsp70-c2 peptide
58c2dbaA_
not modelled 99.2 10 PDB header:structural protein
Chain: A: PDB Molecule:smooth muscle cell associated protein-1, isoform
PDBTitle: the solution structure of the tetratrico peptide repeat of2 human smooth muscle cell associated protein-1, isoform 2
59c2uy1A_
not modelled 99.2 10 PDB header:rna-binding protein
Chain: A: PDB Molecule:cleavage stimulation factor 77;
PDBTitle: crystal structure of cstf-77
60c2kckA_
not modelled 99.2 13 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:tpr repeat;
PDBTitle: nmr solution structure of the northeast structural genomics2 consortium (nesg) target mrr121a
61d1hxia_
not modelled 99.2 20 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
62d1elra_
not modelled 99.2 14 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
63c3qkyA_
not modelled 99.2 9 PDB header:membrane protein
Chain: A: PDB Molecule:outer membrane assembly lipoprotein yfio;
PDBTitle: crystal structure of rhodothermus marinus bamd
64c3rkvA_
not modelled 99.2 18 PDB header:isomerase
Chain: A: PDB Molecule:putative peptidylprolyl isomerase;
PDBTitle: c-terminal domain of protein c56c10.10, a putative peptidylprolyl2 isomerase, from caenorhabditis elegans
65d2fbna1
not modelled 99.2 18 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
66c2fbnA_
not modelled 99.2 18 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:70 kda peptidylprolyl isomerase, putative;
PDBTitle: plasmodium falciparum putative fk506-binding protein2 pfl2275c, c-terminal tpr-containing domain
67c1qz2B_
not modelled 99.2 16 PDB header:isomerase/chaperone
Chain: B: PDB Molecule:fk506-binding protein 4;
PDBTitle: crystal structure of fkbp52 c-terminal domain complex with2 the c-terminal peptide meevd of hsp90
68c2xevB_
not modelled 99.2 16 PDB header:metal binding
Chain: B: PDB Molecule:ybgf;
PDBTitle: crystal structure of the tpr domain of xanthomonas2 campestris ybgf
69d1nzna_
not modelled 99.1 10 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
70c2vsnB_
not modelled 99.1 22 PDB header:transferase
Chain: B: PDB Molecule:xcogt;
PDBTitle: structure and topological arrangement of an o-glcnac2 transferase homolog: insight into molecular control of3 intracellular glycosylation
71d1ihga1
not modelled 99.1 16 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
72c1na3A_
not modelled 99.1 20 PDB header:de novo protein
Chain: A: PDB Molecule:designed protein ctpr2;
PDBTitle: design of stable alpha-helical arrays from an idealized tpr2 motif
73c2katA_
not modelled 99.1 18 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: solution structure of protein bpp2914 from bordetella2 parapertussis. northeast structural genomics consortium3 target bpr206
74d1pc2a_
not modelled 99.1 11 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
75c3q15A_
not modelled 99.0 11 PDB header:hydrolase/kinase
Chain: A: PDB Molecule:response regulator aspartate phosphatase h;
PDBTitle: crystal structure of raph complexed with spo0f
76c2vgxA_
not modelled 99.0 12 PDB header:chaperone
Chain: A: PDB Molecule:chaperone sycd;
PDBTitle: structure of the yersinia enterocolitica type iii secretion2 translocator chaperone sycd
77d1zbpa1
not modelled 99.0 16 Fold:ImpE-like
Superfamily:ImpE-like
Family:ImpE-like
78c1xi4D_
not modelled 98.9 16 PDB header:endocytosis/exocytosis
Chain: D: PDB Molecule:clathrin heavy chain;
PDBTitle: clathrin d6 coat
79d2onda1
not modelled 98.9 14 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:HAT/Suf repeat
80c3k9iA_
not modelled 98.9 13 PDB header:protein binding
Chain: A: PDB Molecule:bh0479 protein;
PDBTitle: crystal structure of putative protein binding protein (np_241345.1)2 from bacillus halodurans at 2.71 a resolution
81d1qqea_
not modelled 98.9 12 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
82c1ltxA_
not modelled 98.9 14 PDB header:transferase/protein binding
Chain: A: PDB Molecule:rab geranylgeranyltransferase alpha subunit;
PDBTitle: structure of rab escort protein-1 in complex with rab2 geranylgeranyl transferase and isoprenoid
83d2hr2a1
not modelled 98.9 15 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:CT2138-like
84c2l6jA_
not modelled 98.8 13 PDB header:protein binding
Chain: A: PDB Molecule:tpr repeat-containing protein associated with hsp90;
PDBTitle: tah1 complexed by meevd
85c2if4A_
not modelled 98.8 20 PDB header:signaling protein
Chain: A: PDB Molecule:atfkbp42;
PDBTitle: crystal structure of a multi-domain immunophilin from2 arabidopsis thaliana
86c1slyA_
not modelled 98.8 18 PDB header:glycosyltransferase
Chain: A: PDB Molecule:70-kda soluble lytic transglycosylase;
PDBTitle: complex of the 70-kda soluble lytic transglycosylase with2 bulgecin a
87c3ulqA_
not modelled 98.8 10 PDB header:gene regulation/transcription activator
Chain: A: PDB Molecule:response regulator aspartate phosphatase f;
PDBTitle: crystal structure of the anti-activator rapf complexed with the2 response regulator coma dna binding domain
88c2kcvA_
not modelled 98.7 17 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:tetratricopeptide repeat domain protein;
PDBTitle: solution nmr structure of tetratricopeptide repeat domain2 protein sru_0103 from salinibacter ruber, northeast3 structural genomics consortium (nesg) target srr115c
89c3fflC_
not modelled 98.6 19 PDB header:cell cycle
Chain: C: PDB Molecule:anaphase-promoting complex subunit 7;
PDBTitle: crystal structure of the n-terminal domain of anaphase-2 promoting complex subunit 7
90c3nf1A_
not modelled 98.6 24 PDB header:motor protein, transport protein
Chain: A: PDB Molecule:kinesin light chain 1;
PDBTitle: crystal structure of the tpr domain of kinesin light chain 1
91d1y8ma1
not modelled 98.6 11 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
92d2ff4a2
not modelled 98.6 17 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:BTAD-like
93c2avpA_
not modelled 98.6 25 PDB header:de novo protein
Chain: A: PDB Molecule:synthetic consensus tpr protein;
PDBTitle: crystal structure of an 8 repeat consensus tpr superhelix
94c3sf4B_
not modelled 98.6 16 PDB header:signaling protein/protein binding
Chain: B: PDB Molecule:g-protein-signaling modulator 2;
PDBTitle: crystal structure of the complex between the conserved cell polarity2 proteins inscuteable and lgn
95c2kc7A_
not modelled 98.5 18 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:bfr218_protein;
PDBTitle: solution nmr structure of bacteroides fragilis protein2 bf1650. northeast structural genomics consortium target3 bfr218
96d1tjca_
not modelled 98.5 12 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
97c3beeB_
not modelled 98.5 14 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:putative yfre protein;
PDBTitle: crystal structure of putative yfre protein from vibrio2 parahaemolyticus
98c3ceqB_
not modelled 98.5 27 PDB header:motor protein, transport protein
Chain: B: PDB Molecule:kinesin light chain 2;
PDBTitle: the tpr domain of human kinesin light chain 2 (hklc2)
99d2pqrb1
not modelled 98.3 12 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
100c3n71A_
not modelled 98.2 15 PDB header:transcription
Chain: A: PDB Molecule:histone lysine methyltransferase smyd1;
PDBTitle: crystal structure of cardiac specific histone methyltransferase smyd1
101c3q3hA_
not modelled 97.6 10 PDB header:transferase
Chain: A: PDB Molecule:hmw1c-like glycosyltransferase;
PDBTitle: crystal structure of the actinobacillus pleuropneumoniae hmw1c2 glycosyltransferase in complex with udp-glc
102c2qfcB_
not modelled 97.6 13 PDB header:transcription regulation
Chain: B: PDB Molecule:plcr protein;
PDBTitle: crystal structure of bacillus thuringiensis plcr complexed with papr
103c3qwvA_
not modelled 97.0 11 PDB header:transferase
Chain: A: PDB Molecule:set and mynd domain-containing protein 2;
PDBTitle: crystal structure of histone lysine methyltransferase smyd2 in complex2 with the cofactor product adohcy
104c2ff4B_
not modelled 96.9 19 PDB header:transcription
Chain: B: PDB Molecule:probable regulatory protein embr;
PDBTitle: mycobacterium tuberculosis embr in complex with low affinity2 phosphopeptide
105c3mekA_
not modelled 96.8 15 PDB header:transferase
Chain: A: PDB Molecule:set and mynd domain-containing protein 3;
PDBTitle: crystal structure of human histone-lysine n-2 methyltransferase smyd3 in complex with s-adenosyl-l-3 methionine
106d1ouva_
not modelled 96.8 13 Fold:alpha-alpha superhelix
Superfamily:HCP-like
Family:HCP-like
107c3mkqA_
not modelled 96.8 13 PDB header:transport protein
Chain: A: PDB Molecule:coatomer beta'-subunit;
PDBTitle: crystal structure of yeast alpha/betaprime-cop subcomplex of the copi2 vesicular coat
108c3oxgA_
not modelled 96.7 16 PDB header:transferase
Chain: A: PDB Molecule:set and mynd domain-containing protein 3;
PDBTitle: human lysine methyltransferase smyd3 in complex with adohcy (form iii)
109c3e4bD_
not modelled 96.6 11 PDB header:protein binding
Chain: D: PDB Molecule:algk;
PDBTitle: crystal structure of algk from pseudomonas fluorescens wcs374r
110c3txmA_
not modelled 96.0 14 PDB header:hydrolase, protein binding
Chain: A: PDB Molecule:26s proteasome regulatory complex subunit p42b;
PDBTitle: crystal structure of rpn6 from drosophila melanogaster, gd(3+) complex
111c3dtkA_
not modelled 95.5 19 PDB header:gene regulation
Chain: A: PDB Molecule:irre protein;
PDBTitle: crystal structure of the irre protein, a central regulator2 of dna damage repair in deinococcaceae
112c2lahA_
not modelled 94.5 10 PDB header:cell cycle, apoptosis
Chain: A: PDB Molecule:mitotic checkpoint serine/threonine-protein kinase bub1;
PDBTitle: solution nmr structure of mitotic checkpoint serine/threonine-protein2 kinase bub1 n-terminal domain from homo sapiens, northeast structural3 genomics consortium target hr5460a (methods development)
113c3lvhA_
not modelled 94.3 17 PDB header:structural protein
Chain: A: PDB Molecule:clathrin heavy chain 1;
PDBTitle: crystal structure of a clathrin heavy chain and clathrin light chain2 complex
114c3kaeC_
not modelled 93.5 13 PDB header:protein binding
Chain: C: PDB Molecule:possible protein of nuclear scaffold;
PDBTitle: cdc27 n-terminus
115d1b89a_
not modelled 90.6 17 Fold:alpha-alpha superhelix
Superfamily:ARM repeat
Family:Clathrin heavy chain proximal leg segment
116c1b89A_
not modelled 90.6 17 PDB header:clathrin
Chain: A: PDB Molecule:protein (clathrin heavy chain);
PDBTitle: clathrin heavy chain proximal leg segment (bovine)
117c2gtqA_
not modelled 90.5 15 PDB header:hydrolase
Chain: A: PDB Molecule:aminopeptidase n;
PDBTitle: crystal structure of aminopeptidase n from human pathogen neisseria2 meningitidis
118c2wviA_
not modelled 90.5 11 PDB header:transferase
Chain: A: PDB Molecule:mitotic checkpoint serine/threonine-protein
PDBTitle: crystal structure of the n-terminal domain of bubr1
119c3rjvA_
not modelled 90.3 18 PDB header:protein binding
Chain: A: PDB Molecule:putative sel1 repeat protein;
PDBTitle: crystal structure of a putative sel1 repeat protein (kpn_04481) from2 klebsiella pneumoniae subsp. pneumoniae at 1.65 a resolution
120c3qnfA_
not modelled 89.5 19 PDB header:hydrolase
Chain: A: PDB Molecule:endoplasmic reticulum aminopeptidase 1;
PDBTitle: crystal structure of the open state of human endoplasmic reticulum2 aminopeptidase 1 erap1

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
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Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0