PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c2lahA_

Fold library id	PDB Header	Molecule	Title
c2lahA_	PDB header: cell cycle, apoptosis	Chain: A: PDB Molecule: mitotic checkpoint serine/threonine-protein kinase bub1;	PDBTitle: solution nmr structure of mitotic checkpoint serine/threonine-protein2 kinase bub1 n-terminal domain from homo sapiens, northeast structural3 genomics consortium target hr5460a (methods development)

Links to external resources
Added to library: Sat May 14 09:01:01 2011

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence M G H H H H H H S H M D T P E N V L Q M L E A H M Q S Y K G N D P L G E W E R Y I Q W V E E N F P E N K E Y L I T L L E H L M K E F L D K K

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T
S S S
T
S S
S
S S
T T S
G

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence K Y H N D P R F I S Y C L K F A E Y N S D L H Q F F E F L Y N H G I G T L S S P L Y I A W A G H L E A Q G E L Q H A S A V L Q R G I Q N Q A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) G G T T
T T
S
T T T T T T B T
T

. . . . . . . . . 150 . . . . . . . . . 160

Sequence E P R E F L Q Q Q Y R L F Q T R L T E T

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) B S T T

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

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Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	M	G	H	H	H	H	H	H	S	H	M	D	T	P	E	N	V	L	Q	M	L	E	A	H	M	Q	S	Y	K	G	N	D	P	L	G	E	W	E	R	Y	I	Q	W	V	E	E	N	F	P	E	N	K	E	Y	L	I	T	L	L	E	H	L	M	K	E	F	L	D	K	K
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			T	T				S	S	S																	T			S	S		S																S	S																T	T	S		G
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	K	Y	H	N	D	P	R	F	I	S	Y	C	L	K	F	A	E	Y	N	S	D	L	H	Q	F	F	E	F	L	Y	N	H	G	I	G	T	L	S	S	P	L	Y	I	A	W	A	G	H	L	E	A	Q	G	E	L	Q	H	A	S	A	V	L	Q	R	G	I	Q	N	Q	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	G	G	T	T													T	T		S												T	T	T	T	T	T	B															T																T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160
Sequence	E	P	R	E	F	L	Q	Q	Q	Y	R	L	F	Q	T	R	L	T	E	T
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	B	S																T	T