Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	P	H	S	L	F	S	T	D	T	D	L	T	A	E	N	L	L	R	L	P	A	E	F	G	C	P	V	W	V	Y	D	A	Q	I	I	R	R	Q	I	A	A	L	K	Q	F	D	V	V	R	F	A	Q	K	A	C	S	N	I	H
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		I	L	R	L	M	R	E	Q	G	V	K	V	D	S	V	S	L	G	E	I	E	R	A	L	A	A	G	Y	N	P	Q	T	H	P	D	D	I	V	F	T	A	D	V	I	D	Q	A	T	L	E	R	V	S	E	L	Q	I	P	V	N
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		A	G	S	V	D	M	L	D	Q	L	G	Q	V	S	P	G	H	R	V	W	L	R	V	N	P	G	F	G	H	G	H	S	Q	K	T	N	T	G	G	E	N	S	K	H	G	I	W	Y	T	D	L	P	A	A	L	D	V	I	Q	R
Secondary structure
SS confidence
Disorder																															?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		H	H	L	Q	L	V	G	I	H	M	H	I	G	S	G	V	D	Y	A	H	L	E	Q	V	C	G	A	M	V	R	Q	V	I	E	F	G	Q	D	L	Q	A	I	S	A	G	G	G	L	S	V	P	Y	Q	Q	G	E	E	A	V	D
Secondary structure
SS confidence
Disorder																																																						?		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		T	E	H	Y	Y	G	L	W	N	A	A	R	E	Q	I	A	R	H	L	G	H	P	V	K	L	E	I	E	P	G	R	F	L	V	A	Q	S	G	V	L	I	T	Q	V	R	S	V	K	Q	M	G	S	R	H	F	V	L	V	D	A
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		G	F	N	D	L	M	R	P	A	M	Y	G	S	Y	H	H	I	S	A	L	A	A	D	G	R	S	L	E	H	A	P	T	V	E	T	V	V	A	G	P	L	C	E	S	G	D	V	F	T	Q	Q	E	G	G	N	V	E	T	R	A
Secondary structure
SS confidence
Disorder																									?	?	?	?	?																									?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		L	P	E	V	K	A	G	D	Y	L	V	L	H	D	T	G	A	Y	G	A	S	M	S	S	N	Y	N	S	R	P	L	L	P	E	V	L	F	D	N	G	Q	A	R	L	I	R	R	R	Q	T	I	E	E	L	L	A	L	E	L	L
Secondary structure
SS confidence
Disorder																																																										?	?	?	?
Disorder confidence
Sequence
Secondary structure
SS confidence
Disorder
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1knw chain A Region: 2 - 420 Aligned: 419 Modelled: 419 Confidence: 100.0% Identity: 100% PDB header:lyase Chain: A: PDB Molecule:diaminopimelate decarboxylase; PDBTitle: crystal structure of diaminopimelate decarboxylase Phyre2 PDB 1tuf chain A Region: 6 - 420 Aligned: 397 Modelled: 408 Confidence: 100.0% Identity: 29% PDB header:lyase Chain: A: PDB Molecule:diaminopimelate decarboxylase; PDBTitle: crystal structure of diaminopimelate decarboxylase from m.2 jannaschi Phyre2 PDB 2o0t chain B Region: 9 - 419 Aligned: 396 Modelled: 411 Confidence: 100.0% Identity: 27% PDB header:lyase Chain: B: PDB Molecule:diaminopimelate decarboxylase; PDBTitle: the three dimensional structure of diaminopimelate decarboxylase from2 mycobacterium tuberculosis reveals a tetrameric enzyme organisation Phyre2 PDB 2on3 chain A Region: 2 - 409 Aligned: 375 Modelled: 389 Confidence: 100.0% Identity: 19% PDB header:lyase Chain: A: PDB Molecule:ornithine decarboxylase; PDBTitle: a structural insight into the inhibition of human and2 leishmania donovani ornithine decarboxylases by 3-aminooxy-3 1-aminopropane Phyre2 PDB 1d7k chain B Region: 17 - 409 Aligned: 369 Modelled: 393 Confidence: 100.0% Identity: 19% PDB header:lyase Chain: B: PDB Molecule:human ornithine decarboxylase; PDBTitle: crystal structure of human ornithine decarboxylase at 2.12 angstroms resolution Phyre2 PDB 2p3e chain A Region: 1 - 419 Aligned: 380 Modelled: 419 Confidence: 100.0% Identity: 33% PDB header:lyase Chain: A: PDB Molecule:diaminopimelate decarboxylase; PDBTitle: crystal structure of aq1208 from aquifex aeolicus Phyre2 PDB 3n2b chain D Region: 8 - 420 Aligned: 371 Modelled: 397 Confidence: 100.0% Identity: 31% PDB header:lyase Chain: D: PDB Molecule:diaminopimelate decarboxylase; PDBTitle: 1.8 angstrom resolution crystal structure of diaminopimelate2 decarboxylase (lysa) from vibrio cholerae. Phyre2 PDB 2qgh chain A Region: 16 - 419 Aligned: 376 Modelled: 400 Confidence: 100.0% Identity: 35% PDB header:lyase Chain: A: PDB Molecule:diaminopimelate decarboxylase; PDBTitle: crystal structure of diaminopimelate decarboxylase from helicobacter2 pylori complexed with l-lysine Phyre2 PDB 2j66 chain A Region: 13 - 419 Aligned: 374 Modelled: 379 Confidence: 100.0% Identity: 28% PDB header:lyase Chain: A: PDB Molecule:btrk; PDBTitle: structural characterisation of btrk decarboxylase from2 butirosin biosynthesis Phyre2 PDB 2yxx chain A Region: 17 - 420 Aligned: 375 Modelled: 403 Confidence: 100.0% Identity: 34% PDB header:lyase Chain: A: PDB Molecule:diaminopimelate decarboxylase; PDBTitle: crystal structure analysis of diaminopimelate decarboxylate (lysa) Phyre2 PDB 3btn chain A Region: 17 - 415 Aligned: 354 Modelled: 379 Confidence: 100.0% Identity: 18% PDB header:biosynthetic protein Chain: A: PDB Molecule:antizyme inhibitor 1; PDBTitle: crystal structure of antizyme inhibitor, an ornithine2 decarboxylase homologous protein Phyre2 PDB 3n29 chain A Region: 22 - 417 Aligned: 357 Modelled: 391 Confidence: 100.0% Identity: 18% PDB header:lyase Chain: A: PDB Molecule:carboxynorspermidine decarboxylase; PDBTitle: crystal structure of carboxynorspermidine decarboxylase complexed with2 norspermidine from campylobacter jejuni Phyre2 PDB 2plj chain A Region: 3 - 400 Aligned: 361 Modelled: 383 Confidence: 100.0% Identity: 21% PDB header:lyase Chain: A: PDB Molecule:lysine/ornithine decarboxylase; PDBTitle: crystal structure of lysine/ornithine decarboxylase complexed with2 putrescine from vibrio vulnificus Phyre2 PDB 3mt1 chain B Region: 24 - 417 Aligned: 338 Modelled: 362 Confidence: 100.0% Identity: 18% PDB header:lyase Chain: B: PDB Molecule:putative carboxynorspermidine decarboxylase protein; PDBTitle: crystal structure of putative carboxynorspermidine decarboxylase2 protein from sinorhizobium meliloti Phyre2 PDB 3nzp chain A Region: 16 - 416 Aligned: 380 Modelled: 394 Confidence: 100.0% Identity: 22% PDB header:lyase Chain: A: PDB Molecule:arginine decarboxylase; PDBTitle: crystal structure of the biosynthetic arginine decarboxylase spea from2 campylobacter jejuni, northeast structural genomics consortium target3 br53 Phyre2 PDB 2nva chain H Region: 17 - 397 Aligned: 354 Modelled: 381 Confidence: 100.0% Identity: 20% PDB header:lyase Chain: H: PDB Molecule:arginine decarboxylase, a207r protein; PDBTitle: the x-ray crystal structure of the paramecium bursaria2 chlorella virus arginine decarboxylase bound to agmatine Phyre2 PDB 3nzq chain B Region: 16 - 416 Aligned: 391 Modelled: 401 Confidence: 100.0% Identity: 18% PDB header:lyase Chain: B: PDB Molecule:biosynthetic arginine decarboxylase; PDBTitle: crystal structure of biosynthetic arginine decarboxylase adc (spea)2 from escherichia coli, northeast structural genomics consortium3 target er600 Phyre2 PDB 3n2o chain A Region: 16 - 416 Aligned: 391 Modelled: 401 Confidence: 100.0% Identity: 18% PDB header:lyase Chain: A: PDB Molecule:biosynthetic arginine decarboxylase; PDBTitle: x-ray crystal structure of arginine decarboxylase complexed with2 arginine from vibrio vulnificus Phyre2 PDB 1njj chain C Region: 12 - 388 Aligned: 341 Modelled: 361 Confidence: 100.0% Identity: 23% PDB header:lyase Chain: C: PDB Molecule:ornithine decarboxylase; PDBTitle: crystal structure determination of t. brucei ornithine2 decarboxylase bound to d-ornithine and to g418 Phyre2 PDB 1knw chain A domain 2 Region: 32 - 278 Aligned: 247 Modelled: 247 Confidence: 100.0% Identity: 100% Fold: TIM beta/alpha-barrel Superfamily: PLP-binding barrel Family: Alanine racemase-like, N-terminal domain Phyre2 1 c1knwA_ 2 c1tufA_ 3 c2o0tB_ 4 c2on3A_ 5 c1d7kB_ 6 c2p3eA_ 7 c3n2bD_ 8 c2qghA_ 9 c2j66A_ 10 c2yxxA_ 11 c3btnA_ 12 c3n29A_ 13 c2pljA_ 14 c3mt1B_ 15 c3nzpA_ 16 c2nvaH_ 17 c3nzqB_ 18 c3n2oA_ 19 c1njjC_ 20 d1knwa2 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c1knwA_ 100.0 100 PDB header:lyase Chain: A: PDB Molecule:diaminopimelate decarboxylase; PDBTitle: crystal structure of diaminopimelate decarboxylase 2 c1tufA_ 100.0 29 PDB header:lyase Chain: A: PDB Molecule:diaminopimelate decarboxylase; PDBTitle: crystal structure of diaminopimelate decarboxylase from m.2 jannaschi 3 c2o0tB_ 100.0 27 PDB header:lyase Chain: B: PDB Molecule:diaminopimelate decarboxylase; PDBTitle: the three dimensional structure of diaminopimelate decarboxylase from2 mycobacterium tuberculosis reveals a tetrameric enzyme organisation 4 c2on3A_ 100.0 19 PDB header:lyase Chain: A: PDB Molecule:ornithine decarboxylase; PDBTitle: a structural insight into the inhibition of human and2 leishmania donovani ornithine decarboxylases by 3-aminooxy-3 1-aminopropane 5 c1d7kB_ 100.0 19 PDB header:lyase Chain: B: PDB Molecule:human ornithine decarboxylase; PDBTitle: crystal structure of human ornithine decarboxylase at 2.12 angstroms resolution 6 c2p3eA_ 100.0 33 PDB header:lyase Chain: A: PDB Molecule:diaminopimelate decarboxylase; PDBTitle: crystal structure of aq1208 from aquifex aeolicus 7 c3n2bD_ 100.0 31 PDB header:lyase Chain: D: PDB Molecule:diaminopimelate decarboxylase; PDBTitle: 1.8 angstrom resolution crystal structure of diaminopimelate2 decarboxylase (lysa) from vibrio cholerae. 8 c2qghA_ 100.0 35 PDB header:lyase Chain: A: PDB Molecule:diaminopimelate decarboxylase; PDBTitle: crystal structure of diaminopimelate decarboxylase from helicobacter2 pylori complexed with l-lysine 9 c2j66A_ 100.0 28 PDB header:lyase Chain: A: PDB Molecule:btrk; PDBTitle: structural characterisation of btrk decarboxylase from2 butirosin biosynthesis 10 c2yxxA_ 100.0 34 PDB header:lyase Chain: A: PDB Molecule:diaminopimelate decarboxylase; PDBTitle: crystal structure analysis of diaminopimelate decarboxylate (lysa) 11 c3btnA_ 100.0 18 PDB header:biosynthetic protein Chain: A: PDB Molecule:antizyme inhibitor 1; PDBTitle: crystal structure of antizyme inhibitor, an ornithine2 decarboxylase homologous protein 12 c3n29A_ 100.0 18 PDB header:lyase Chain: A: PDB Molecule:carboxynorspermidine decarboxylase; PDBTitle: crystal structure of carboxynorspermidine decarboxylase complexed with2 norspermidine from campylobacter jejuni 13 c2pljA_ 100.0 21 PDB header:lyase Chain: A: PDB Molecule:lysine/ornithine decarboxylase; PDBTitle: crystal structure of lysine/ornithine decarboxylase complexed with2 putrescine from vibrio vulnificus 14 c3mt1B_ 100.0 18 PDB header:lyase Chain: B: PDB Molecule:putative carboxynorspermidine decarboxylase protein; PDBTitle: crystal structure of putative carboxynorspermidine decarboxylase2 protein from sinorhizobium meliloti 15 c3nzpA_ 100.0 22 PDB header:lyase Chain: A: PDB Molecule:arginine decarboxylase; PDBTitle: crystal structure of the biosynthetic arginine decarboxylase spea from2 campylobacter jejuni, northeast structural genomics consortium target3 br53 16 c2nvaH_ 100.0 20 PDB header:lyase Chain: H: PDB Molecule:arginine decarboxylase, a207r protein; PDBTitle: the x-ray crystal structure of the paramecium bursaria2 chlorella virus arginine decarboxylase bound to agmatine 17 c3nzqB_ 100.0 18 PDB header:lyase Chain: B: PDB Molecule:biosynthetic arginine decarboxylase; PDBTitle: crystal structure of biosynthetic arginine decarboxylase adc (spea)2 from escherichia coli, northeast structural genomics consortium3 target er600 18 c3n2oA_ 100.0 18 PDB header:lyase Chain: A: PDB Molecule:biosynthetic arginine decarboxylase; PDBTitle: x-ray crystal structure of arginine decarboxylase complexed with2 arginine from vibrio vulnificus 19 c1njjC_ 100.0 23 PDB header:lyase Chain: C: PDB Molecule:ornithine decarboxylase; PDBTitle: crystal structure determination of t. brucei ornithine2 decarboxylase bound to d-ornithine and to g418 20 d1knwa2 100.0 100 Fold:TIM beta/alpha-barrel Superfamily:PLP-binding barrel Family:Alanine racemase-like, N-terminal domain 21 d1d7ka2 not modelled 100.0 18 Fold:TIM beta/alpha-barrel Superfamily:PLP-binding barrel Family:Alanine racemase-like, N-terminal domain 22 d1twia2 not modelled 100.0 25 Fold:TIM beta/alpha-barrel Superfamily:PLP-binding barrel Family:Alanine racemase-like, N-terminal domain 23 d1f3ta2 not modelled 100.0 23 Fold:TIM beta/alpha-barrel Superfamily:PLP-binding barrel Family:Alanine racemase-like, N-terminal domain 24 d1hkva2 not modelled 100.0 23 Fold:TIM beta/alpha-barrel Superfamily:PLP-binding barrel Family:Alanine racemase-like, N-terminal domain 25 d7odca2 not modelled 100.0 18 Fold:TIM beta/alpha-barrel Superfamily:PLP-binding barrel Family:Alanine racemase-like, N-terminal domain 26 d1knwa1 not modelled 100.0 93 Fold:Domain of alpha and beta subunits of F1 ATP synthase-like Superfamily:Alanine racemase C-terminal domain-like Family:Eukaryotic ODC-like 27 d1hkva1 not modelled 100.0 33 Fold:Domain of alpha and beta subunits of F1 ATP synthase-like Superfamily:Alanine racemase C-terminal domain-like Family:Eukaryotic ODC-like 28 d1twia1 not modelled 100.0 41 Fold:Domain of alpha and beta subunits of F1 ATP synthase-like Superfamily:Alanine racemase C-terminal domain-like Family:Eukaryotic ODC-like 29 c3anuA_ not modelled 100.0 18 PDB header:lyase Chain: A: PDB Molecule:d-serine dehydratase; PDBTitle: crystal structure of d-serine dehydratase from chicken kidney 30 c1xfcB_ not modelled 100.0 18 PDB header:isomerase Chain: B: PDB Molecule:alanine racemase; PDBTitle: the 1.9 a crystal structure of alanine racemase from mycobacterium2 tuberculosis contains a conserved entryway into the active site 31 c3oo2B_ not modelled 100.0 17 PDB header:isomerase Chain: B: PDB Molecule:alanine racemase 1; PDBTitle: 2.37 angstrom resolution crystal structure of an alanine racemase2 (alr) from staphylococcus aureus subsp. aureus col 32 c3llxA_ not modelled 100.0 13 PDB header:isomerase Chain: A: PDB Molecule:predicted amino acid aldolase or racemase; PDBTitle: crystal structure of an ala racemase-like protein (il1761) from2 idiomarina loihiensis at 1.50 a resolution 33 c3kw3B_ not modelled 100.0 13 PDB header:isomerase Chain: B: PDB Molecule:alanine racemase; PDBTitle: crystal structure of alanine racemase from bartonella henselae with2 covalently bound pyridoxal phosphate 34 c3gwqB_ not modelled 100.0 21 PDB header:lyase Chain: B: PDB Molecule:d-serine deaminase; PDBTitle: crystal structure of a putative d-serine deaminase (bxe_a4060) from2 burkholderia xenovorans lb400 at 2.00 a resolution 35 c1vftA_ not modelled 100.0 19 PDB header:isomerase Chain: A: PDB Molecule:alanine racemase; PDBTitle: crystal structure of l-cycloserine-bound form of alanine2 racemase from d-cycloserine-producing streptomyces3 lavendulae 36 c3oo2A_ not modelled 100.0 18 PDB header:isomerase Chain: A: PDB Molecule:alanine racemase 1; PDBTitle: 2.37 angstrom resolution crystal structure of an alanine racemase2 (alr) from staphylococcus aureus subsp. aureus col 37 c2dy3B_ not modelled 100.0 15 PDB header:isomerase Chain: B: PDB Molecule:alanine racemase; PDBTitle: crystal structure of alanine racemase from corynebacterium glutamicum 38 d7odca1 not modelled 100.0 19 Fold:Domain of alpha and beta subunits of F1 ATP synthase-like Superfamily:Alanine racemase C-terminal domain-like Family:Eukaryotic ODC-like 39 d1d7ka1 not modelled 99.9 20 Fold:Domain of alpha and beta subunits of F1 ATP synthase-like Superfamily:Alanine racemase C-terminal domain-like Family:Eukaryotic ODC-like 40 d1f3ta1 not modelled 99.9 22 Fold:Domain of alpha and beta subunits of F1 ATP synthase-like Superfamily:Alanine racemase C-terminal domain-like Family:Eukaryotic ODC-like 41 c1niuA_ not modelled 99.9 16 PDB header:isomerase Chain: A: PDB Molecule:alanine racemase; PDBTitle: alanine racemase with bound inhibitor derived from l-2 cycloserine 42 c3e6eC_ not modelled 99.9 21 PDB header:isomerase Chain: C: PDB Molecule:alanine racemase; PDBTitle: crystal structure of alanine racemase from e.faecalis2 complex with cycloserine 43 c2odoC_ not modelled 99.9 16 PDB header:isomerase Chain: C: PDB Molecule:alanine racemase; PDBTitle: crystal structure of pseudomonas fluorescens alanine racemase 44 c3hurA_ not modelled 99.9 20 PDB header:isomerase Chain: A: PDB Molecule:alanine racemase; PDBTitle: crystal structure of alanine racemase from oenococcus oeni 45 d2toda1 not modelled 99.9 22 Fold:Domain of alpha and beta subunits of F1 ATP synthase-like Superfamily:Alanine racemase C-terminal domain-like Family:Eukaryotic ODC-like 46 c3mubB_ not modelled 99.9 16 PDB header:isomerase Chain: B: PDB Molecule:alanine racemase; PDBTitle: the crystal structure of alanine racemase from streptococcus2 pneumoniae 47 c3co8B_ not modelled 99.9 19 PDB header:isomerase Chain: B: PDB Molecule:alanine racemase; PDBTitle: crystal structure of alanine racemase from oenococcus oeni 48 c2rjgC_ not modelled 99.9 19 PDB header:isomerase Chain: C: PDB Molecule:alanine racemase; PDBTitle: crystal structure of biosynthetic alaine racemase from escherichia2 coli 49 d1njjb1 not modelled 99.9 23 Fold:Domain of alpha and beta subunits of F1 ATP synthase-like Superfamily:Alanine racemase C-terminal domain-like Family:Eukaryotic ODC-like 50 d1vfsa2 not modelled 99.8 17 Fold:TIM beta/alpha-barrel Superfamily:PLP-binding barrel Family:Alanine racemase-like, N-terminal domain 51 d1bd0a2 not modelled 99.8 16 Fold:TIM beta/alpha-barrel Superfamily:PLP-binding barrel Family:Alanine racemase-like, N-terminal domain 52 d1rcqa2 not modelled 99.7 13 Fold:TIM beta/alpha-barrel Superfamily:PLP-binding barrel Family:Alanine racemase-like, N-terminal domain 53 c2vd9A_ not modelled 99.7 17 PDB header:isomerase Chain: A: PDB Molecule:alanine racemase; PDBTitle: the crystal structure of alanine racemase from bacillus2 anthracis (ba0252) with bound l-ala-p 54 c1w8gA_ not modelled 99.7 13 PDB header:plp-binding protein Chain: A: PDB Molecule:hypothetical upf0001 protein yggs; PDBTitle: crystal structure of e. coli k-12 yggs 55 c3r79B_ not modelled 99.6 13 PDB header:structure genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of an uncharactertized protein from agrobacterium2 tumefaciens 56 c3cpgA_ not modelled 99.5 12 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of an unknown protein from bifidobacterium2 adolescentis 57 d1ct5a_ not modelled 99.2 10 Fold:TIM beta/alpha-barrel Superfamily:PLP-binding barrel Family:"Hypothetical" protein ybl036c 58 d1bd0a1 not modelled 97.6 17 Fold:Domain of alpha and beta subunits of F1 ATP synthase-like Superfamily:Alanine racemase C-terminal domain-like Family:Alanine racemase 59 d1rcqa1 not modelled 97.1 20 Fold:Domain of alpha and beta subunits of F1 ATP synthase-like Superfamily:Alanine racemase C-terminal domain-like Family:Alanine racemase 60 d1vfsa1 not modelled 96.7 25 Fold:Domain of alpha and beta subunits of F1 ATP synthase-like Superfamily:Alanine racemase C-terminal domain-like Family:Alanine racemase 61 d1ur4a_ not modelled 80.8 17 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:beta-glycanases 62 d1vc4a_ not modelled 76.6 20 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 63 d1vhca_ not modelled 70.2 19 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 64 d2tpsa_ not modelled 67.1 20 Fold:TIM beta/alpha-barrel Superfamily:Thiamin phosphate synthase Family:Thiamin phosphate synthase 65 d2q02a1 not modelled 66.8 13 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:IolI-like 66 d1goxa_ not modelled 66.1 16 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 67 c1ydoC_ not modelled 63.9 20 PDB header:lyase Chain: C: PDB Molecule:hmg-coa lyase; PDBTitle: crystal structure of the bacillis subtilis hmg-coa lyase, northeast2 structural genomics target sr181. 68 c1vc3B_ not modelled 62.7 25 PDB header:lyase Chain: B: PDB Molecule:l-aspartate-alpha-decarboxylase heavy chain; PDBTitle: crystal structure of l-aspartate-alpha-decarboxylase 69 d1wbha1 not modelled 57.5 9 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 70 c2ylaA_ not modelled 55.0 8 PDB header:hydrolase Chain: A: PDB Molecule:beta-n-acetylhexosaminidase; PDBTitle: inhibition of the pneumococcal virulence factor strh and2 molecular insights into n-glycan recognition and3 hydrolysis 71 c3plxB_ not modelled 54.9 17 PDB header:lyase Chain: B: PDB Molecule:aspartate 1-decarboxylase; PDBTitle: the crystal structure of aspartate alpha-decarboxylase from2 campylobacter jejuni subsp. jejuni nctc 11168 72 d1a53a_ not modelled 52.3 14 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 73 c2yl8A_ not modelled 52.1 7 PDB header:hydrolase Chain: A: PDB Molecule:beta-n-acetylhexosaminidase; PDBTitle: inhibition of the pneumococcal virulence factor strh and2 molecular insights into n-glycan recognition and3 hydrolysis 74 c3nm3D_ not modelled 46.5 15 PDB header:transferase Chain: D: PDB Molecule:thiamine biosynthetic bifunctional enzyme; PDBTitle: the crystal structure of candida glabrata thi6, a bifunctional enzyme2 involved in thiamin biosyhthesis of eukaryotes 75 c2hk1D_ not modelled 45.5 10 PDB header:isomerase Chain: D: PDB Molecule:d-psicose 3-epimerase; PDBTitle: crystal structure of d-psicose 3-epimerase (dpease) in the presence of2 d-fructose 76 c2kytA_ not modelled 42.8 25 PDB header:hydrolase Chain: A: PDB Molecule:group xvi phospholipase a2; PDBTitle: solution struture of the h-rev107 n-terminal domain 77 c3nsnA_ not modelled 40.3 13 PDB header:hydrolase Chain: A: PDB Molecule:n-acetylglucosaminidase; PDBTitle: crystal structure of insect beta-n-acetyl-d-hexosaminidase ofhex12 complexed with tmg-chitotriomycin 78 d2z1ca1 not modelled 40.0 38 Fold:OB-fold Superfamily:HupF/HypC-like Family:HupF/HypC-like 79 c2w5fB_ not modelled 39.5 15 PDB header:hydrolase Chain: B: PDB Molecule:endo-1,4-beta-xylanase y; PDBTitle: high resolution crystallographic structure of the2 clostridium thermocellum n-terminal endo-1,4-beta-d-3 xylanase 10b (xyn10b) cbm22-1-gh10 modules complexed with4 xylohexaose 80 d1saza1 not modelled 39.0 38 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:Acetokinase-like 81 c2ftpA_ not modelled 37.8 21 PDB header:lyase Chain: A: PDB Molecule:hydroxymethylglutaryl-coa lyase; PDBTitle: crystal structure of hydroxymethylglutaryl-coa lyase from pseudomonas2 aeruginosa 82 d1gz0f2 not modelled 37.5 13 Fold:Bacillus chorismate mutase-like Superfamily:L30e-like Family:RNA 2'-O ribose methyltransferase substrate binding domain 83 d2csga1 not modelled 37.4 15 Fold:Double-stranded beta-helix Superfamily:Clavaminate synthase-like Family:YbiU-like 84 d1xfka_ not modelled 37.1 16 Fold:Arginase/deacetylase Superfamily:Arginase/deacetylase Family:Arginase-like amidino hydrolases 85 c2eivH_ not modelled 36.5 12 PDB header:hydrolase Chain: H: PDB Molecule:arginase; PDBTitle: crystal structure of the arginase from thermus thermophilus 86 d1uuma_ not modelled 35.1 20 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 87 c1pyuD_ not modelled 34.5 9 PDB header:lyase Chain: D: PDB Molecule:aspartate 1-decarboxylase alfa chain; PDBTitle: processed aspartate decarboxylase mutant with ser25 mutated to cys 88 c3cqkB_ not modelled 34.4 11 PDB header:isomerase Chain: B: PDB Molecule:l-ribulose-5-phosphate 3-epimerase ulae; PDBTitle: crystal structure of l-xylulose-5-phosphate 3-epimerase ulae (form b)2 complex with zn2+ and sulfate 89 c3rcnA_ not modelled 34.1 18 PDB header:hydrolase Chain: A: PDB Molecule:beta-n-acetylhexosaminidase; PDBTitle: crystal structure of beta-n-acetylhexosaminidase from arthrobacter2 aurescens 90 c2dbiA_ not modelled 33.9 15 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein ybiu; PDBTitle: crystal structure of a hypothetical protein jw0805 from2 escherichia coli 91 c3bleA_ not modelled 33.5 16 PDB header:transferase Chain: A: PDB Molecule:citramalate synthase from leptospira interrogans; PDBTitle: crystal structure of the catalytic domain of licms in2 complexed with malonate 92 d1tz9a_ not modelled 33.2 23 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:UxuA-like 93 c1pt1B_ not modelled 32.5 9 PDB header:lyase Chain: B: PDB Molecule:aspartate 1-decarboxylase; PDBTitle: unprocessed pyruvoyl dependent aspartate decarboxylase with histidine2 11 mutated to alanine 94 c3lmyA_ not modelled 32.2 17 PDB header:hydrolase Chain: A: PDB Molecule:beta-hexosaminidase subunit beta; PDBTitle: the crystal structure of beta-hexosaminidase b in complex with2 pyrimethamine 95 d2c0ha1 not modelled 31.7 18 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:beta-glycanases 96 c2kksA_ not modelled 31.7 13 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: solution structure of protein dsy2949 from desulfitobacterium2 hafniense. northeast structural genomics consortium target dhr27 97 d3eeqa1 not modelled 31.3 14 Fold:CobE/GbiG C-terminal domain-like Superfamily:CobE/GbiG C-terminal domain-like Family:CobE/GbiG C-terminal domain-like 98 c3navB_ not modelled 30.8 12 PDB header:lyase Chain: B: PDB Molecule:tryptophan synthase alpha chain; PDBTitle: crystal structure of an alpha subunit of tryptophan synthase from2 vibrio cholerae o1 biovar el tor str. n16961 99 c3ktcB_ not modelled 30.8 17 PDB header:isomerase Chain: B: PDB Molecule:xylose isomerase; PDBTitle: crystal structure of putative sugar isomerase (yp_050048.1) from2 erwinia carotovora atroseptica scri1043 at 1.54 a resolution 100 c3ju2A_ not modelled 30.7 22 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein smc04130; PDBTitle: crystal structure of protein smc04130 from sinorhizobium meliloti 1021 101 d3by5a1 not modelled 30.5 5 Fold:CobE/GbiG C-terminal domain-like Superfamily:CobE/GbiG C-terminal domain-like Family:CobE/GbiG C-terminal domain-like 102 c3by5A_ not modelled 30.5 5 PDB header:biosynthetic protein Chain: A: PDB Molecule:cobalamin biosynthesis protein; PDBTitle: crystal structure of cobalamin biosynthesis protein chig from2 agrobacterium tumefaciens str. c58 103 d2ceva_ not modelled 30.2 14 Fold:Arginase/deacetylase Superfamily:Arginase/deacetylase Family:Arginase-like amidino hydrolases 104 d1gz0a2 not modelled 29.6 13 Fold:Bacillus chorismate mutase-like Superfamily:L30e-like Family:RNA 2'-O ribose methyltransferase substrate binding domain 105 d3bula2 not modelled 29.4 14 Fold:Flavodoxin-like Superfamily:Cobalamin (vitamin B12)-binding domain Family:Cobalamin (vitamin B12)-binding domain 106 d2ot2a1 not modelled 29.0 17 Fold:OB-fold Superfamily:HupF/HypC-like Family:HupF/HypC-like 107 d1zj8a1 not modelled 28.5 16 Fold:Ferredoxin-like Superfamily:Nitrite/Sulfite reductase N-terminal domain-like Family:Duplicated SiR/NiR-like domains 1 and 3 108 c1xrsB_ not modelled 28.0 7 PDB header:isomerase Chain: B: PDB Molecule:d-lysine 5,6-aminomutase beta subunit; PDBTitle: crystal structure of lysine 5,6-aminomutase in complex with plp,2 cobalamin, and 5'-deoxyadenosine 109 c2ou4C_ not modelled 27.3 7 PDB header:isomerase Chain: C: PDB Molecule:d-tagatose 3-epimerase; PDBTitle: crystal structure of d-tagatose 3-epimerase from2 pseudomonas cichorii 110 d1xi3a_ not modelled 27.2 20 Fold:TIM beta/alpha-barrel Superfamily:Thiamin phosphate synthase Family:Thiamin phosphate synthase 111 c2yciX_ not modelled 27.0 15 PDB header:transferase Chain: X: PDB Molecule:5-methyltetrahydrofolate corrinoid/iron sulfur protein PDBTitle: methyltransferase native 112 d1i60a_ not modelled 26.9 13 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:IolI-like 113 c3ivuB_ not modelled 26.7 14 PDB header:transferase Chain: B: PDB Molecule:homocitrate synthase, mitochondrial; PDBTitle: homocitrate synthase lys4 bound to 2-og 114 c2a7nA_ not modelled 26.5 10 PDB header:oxidoreductase Chain: A: PDB Molecule:l(+)-mandelate dehydrogenase; PDBTitle: crystal structure of the g81a mutant of the active chimera of (s)-2 mandelate dehydrogenase 115 d1xria_ not modelled 26.0 17 Fold:(Phosphotyrosine protein) phosphatases II Superfamily:(Phosphotyrosine protein) phosphatases II Family:Dual specificity phosphatase-like 116 d1aopa2 not modelled 25.9 10 Fold:Ferredoxin-like Superfamily:Nitrite/Sulfite reductase N-terminal domain-like Family:Duplicated SiR/NiR-like domains 1 and 3 117 d1ppya_ not modelled 25.8 8 Fold:Double psi beta-barrel Superfamily:ADC-like Family:Pyruvoyl dependent aspartate decarboxylase, ADC 118 d2w6ka1 not modelled 25.3 18 Fold:CobE/GbiG C-terminal domain-like Superfamily:CobE/GbiG C-terminal domain-like Family:CobE/GbiG C-terminal domain-like 119 c2zdsB_ not modelled 25.1 11 PDB header:dna binding protein Chain: B: PDB Molecule:putative dna-binding protein; PDBTitle: crystal structure of sco6571 from streptomyces coelicolor2 a3(2) 120 c2c3zA_ not modelled 25.1 18 PDB header:lyase Chain: A: PDB Molecule:indole-3-glycerol phosphate synthase; PDBTitle: crystal structure of a truncated variant of indole-3-2 glycerol phosphate synthase from sulfolobus solfataricus

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0