Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	K	I	V	E	V	K	H	P	L	V	K	H	K	L	G	L	M	R	E	Q	D	I	S	T	K	R	F	R	E	L	A	S	E	V	G	S	L	L	T	Y	E	A	T	A	D	L	E	T	E	K	V	T	I	E	G	W	N	G	P
Secondary structure
SS confidence
Disorder		?	?				?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		V	E	I	D	Q	I	K	G	K	K	I	T	V	V	P	I	L	R	A	G	L	G	M	M	D	G	V	L	E	N	V	P	S	A	R	I	S	V	V	G	M	Y	R	N	E	E	T	L	E	P	V	P	Y	F	Q	K	L	V	S	N
Secondary structure
SS confidence
Disorder																																														?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		I	D	E	R	M	A	L	I	V	D	P	M	L	A	T	G	G	S	V	I	A	T	I	D	L	L	K	K	A	G	C	S	S	I	K	V	L	V	L	V	A	A	P	E	G	I	A	A	L	E	K	A	H	P	D	V	E	L	Y	T
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.
Sequence		A	S	I	D	Q	G	L	N	E	H	G	Y	I	I	P	G	L	G	D	A	G	D	K	I	F	G	T	K
Secondary structure
SS confidence
Disorder																											?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1i5e chain A Region: 2 - 208 Aligned: 207 Modelled: 207 Confidence: 100.0% Identity: 54% Fold: PRTase-like Superfamily: PRTase-like Family: Phosphoribosyltransferases (PRTases) Phyre2 PDB 2ehj chain A Region: 2 - 208 Aligned: 207 Modelled: 207 Confidence: 100.0% Identity: 100% PDB header:transferase Chain: A: PDB Molecule:uracil phosphoribosyltransferase; PDBTitle: structure of uracil phosphoribosyl transferase Phyre2 PDB 1o5o chain A Region: 2 - 208 Aligned: 207 Modelled: 207 Confidence: 100.0% Identity: 50% Fold: PRTase-like Superfamily: PRTase-like Family: Phosphoribosyltransferases (PRTases) Phyre2 PDB 1bd3 chain A Region: 2 - 207 Aligned: 206 Modelled: 206 Confidence: 100.0% Identity: 33% Fold: PRTase-like Superfamily: PRTase-like Family: Phosphoribosyltransferases (PRTases) Phyre2 PDB 2e55 chain D Region: 3 - 208 Aligned: 205 Modelled: 206 Confidence: 100.0% Identity: 40% PDB header:transferase Chain: D: PDB Molecule:uracil phosphoribosyltransferase; PDBTitle: structure of aq2163 protein from aquifex aeolicus Phyre2 PDB 3dmp chain D Region: 2 - 206 Aligned: 203 Modelled: 205 Confidence: 100.0% Identity: 46% PDB header:transferase Chain: D: PDB Molecule:uracil phosphoribosyltransferase; PDBTitle: 2.6 a crystal structure of uracil phosphoribosyltransferase2 from burkholderia pseudomallei Phyre2 PDB 1v9s chain A domain 1 Region: 1 - 208 Aligned: 199 Modelled: 207 Confidence: 100.0% Identity: 49% Fold: PRTase-like Superfamily: PRTase-like Family: Phosphoribosyltransferases (PRTases) Phyre2 PDB 1xtt chain A domain 1 Region: 2 - 206 Aligned: 205 Modelled: 205 Confidence: 100.0% Identity: 30% Fold: PRTase-like Superfamily: PRTase-like Family: Phosphoribosyltransferases (PRTases) Phyre2 PDB 1qb7 chain A Region: 72 - 207 Aligned: 136 Modelled: 136 Confidence: 99.9% Identity: 14% Fold: PRTase-like Superfamily: PRTase-like Family: Phosphoribosyltransferases (PRTases) Phyre2 PDB 1yfz chain A Region: 24 - 205 Aligned: 155 Modelled: 159 Confidence: 99.4% Identity: 16% PDB header:transferase Chain: A: PDB Molecule:hypoxanthine-guanine phosphoribosyltransferase; PDBTitle: novel imp binding in feedback inhibition of hypoxanthine-guanine2 phosphoribosyltransferase from thermoanaerobacter tengcongensis Phyre2 PDB 1yfz chain A domain 1 Region: 24 - 205 Aligned: 155 Modelled: 159 Confidence: 99.4% Identity: 16% Fold: PRTase-like Superfamily: PRTase-like Family: Phosphoribosyltransferases (PRTases) Phyre2 PDB 3kb8 chain A Region: 24 - 165 Aligned: 119 Modelled: 119 Confidence: 99.3% Identity: 20% PDB header:transferase Chain: A: PDB Molecule:hypoxanthine phosphoribosyltransferase; PDBTitle: 2.09 angstrom resolution structure of a hypoxanthine-guanine2 phosphoribosyltransferase (hpt-1) from bacillus anthracis str. 'ames3 ancestor' in complex with gmp Phyre2 PDB 1p17 chain B Region: 24 - 165 Aligned: 126 Modelled: 126 Confidence: 99.3% Identity: 15% Fold: PRTase-like Superfamily: PRTase-like Family: Phosphoribosyltransferases (PRTases) Phyre2 PDB 1wd5 chain A Region: 65 - 185 Aligned: 118 Modelled: 121 Confidence: 99.3% Identity: 23% Fold: PRTase-like Superfamily: PRTase-like Family: Phosphoribosyltransferases (PRTases) Phyre2 PDB 1tc1 chain A Region: 24 - 165 Aligned: 124 Modelled: 126 Confidence: 99.3% Identity: 15% Fold: PRTase-like Superfamily: PRTase-like Family: Phosphoribosyltransferases (PRTases) Phyre2 PDB 2igb chain A domain 1 Region: 24 - 160 Aligned: 115 Modelled: 115 Confidence: 99.3% Identity: 21% Fold: PRTase-like Superfamily: PRTase-like Family: Phosphoribosyltransferases (PRTases) Phyre2 PDB 1cjb chain A Region: 24 - 160 Aligned: 114 Modelled: 114 Confidence: 99.3% Identity: 16% Fold: PRTase-like Superfamily: PRTase-like Family: Phosphoribosyltransferases (PRTases) Phyre2 PDB 1a3c chain A Region: 24 - 160 Aligned: 110 Modelled: 111 Confidence: 99.2% Identity: 24% Fold: PRTase-like Superfamily: PRTase-like Family: Phosphoribosyltransferases (PRTases) Phyre2 PDB 1z7g chain A domain 1 Region: 24 - 160 Aligned: 114 Modelled: 114 Confidence: 99.2% Identity: 17% Fold: PRTase-like Superfamily: PRTase-like Family: Phosphoribosyltransferases (PRTases) Phyre2 PDB 1pzm chain B Region: 24 - 165 Aligned: 120 Modelled: 125 Confidence: 99.2% Identity: 11% PDB header:transferase Chain: B: PDB Molecule:hypoxanthine-guanine phosphoribosyltransferase; PDBTitle: crystal structure of hgprt-ase from leishmania tarentolae in complex2 with gmp Phyre2 1 d1i5ea_ 2 c2ehjA_ 3 d1o5oa_ 4 d1bd3a_ 5 c2e55D_ 6 c3dmpD_ 7 d1v9sa1 8 d1xtta1 9 d1qb7a_ 10 c1yfzA_ 11 d1yfza1 12 c3kb8A_ 13 d1p17b_ 14 d1wd5a_ 15 d1tc1a_ 16 d2igba1 17 d1cjba_ 18 d1a3ca_ 19 d1z7ga1 20 c1pzmB_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1i5ea_ 100.0 54 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 2 c2ehjA_ 100.0 100 PDB header:transferase Chain: A: PDB Molecule:uracil phosphoribosyltransferase; PDBTitle: structure of uracil phosphoribosyl transferase 3 d1o5oa_ 100.0 50 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 4 d1bd3a_ 100.0 33 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 5 c2e55D_ 100.0 40 PDB header:transferase Chain: D: PDB Molecule:uracil phosphoribosyltransferase; PDBTitle: structure of aq2163 protein from aquifex aeolicus 6 c3dmpD_ 100.0 46 PDB header:transferase Chain: D: PDB Molecule:uracil phosphoribosyltransferase; PDBTitle: 2.6 a crystal structure of uracil phosphoribosyltransferase2 from burkholderia pseudomallei 7 d1v9sa1 100.0 49 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 8 d1xtta1 100.0 30 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 9 d1qb7a_ 99.9 14 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 10 c1yfzA_ 99.4 16 PDB header:transferase Chain: A: PDB Molecule:hypoxanthine-guanine phosphoribosyltransferase; PDBTitle: novel imp binding in feedback inhibition of hypoxanthine-guanine2 phosphoribosyltransferase from thermoanaerobacter tengcongensis 11 d1yfza1 99.4 16 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 12 c3kb8A_ 99.3 20 PDB header:transferase Chain: A: PDB Molecule:hypoxanthine phosphoribosyltransferase; PDBTitle: 2.09 angstrom resolution structure of a hypoxanthine-guanine2 phosphoribosyltransferase (hpt-1) from bacillus anthracis str. 'ames3 ancestor' in complex with gmp 13 d1p17b_ 99.3 15 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 14 d1wd5a_ 99.3 23 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 15 d1tc1a_ 99.3 15 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 16 d2igba1 99.3 21 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 17 d1cjba_ 99.3 16 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 18 d1a3ca_ 99.2 24 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 19 d1z7ga1 99.2 17 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 20 c1pzmB_ 99.2 11 PDB header:transferase Chain: B: PDB Molecule:hypoxanthine-guanine phosphoribosyltransferase; PDBTitle: crystal structure of hgprt-ase from leishmania tarentolae in complex2 with gmp 21 c2jbhA_ not modelled 99.2 21 PDB header:transferase Chain: A: PDB Molecule:phosphoribosyltransferase domain-containing protein 1; PDBTitle: human phosphoribosyl transferase domain containing 1 22 d1fsga_ not modelled 99.2 18 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 23 d1ufra_ not modelled 99.2 19 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 24 d1pzma_ not modelled 99.2 10 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 25 d1vdma1 not modelled 99.2 21 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 26 c3o7mD_ not modelled 99.2 17 PDB header:transferase Chain: D: PDB Molecule:hypoxanthine phosphoribosyltransferase; PDBTitle: 1.98 angstrom resolution crystal structure of a hypoxanthine-guanine2 phosphoribosyltransferase (hpt-2) from bacillus anthracis str. 'ames3 ancestor' 27 d1w30a_ not modelled 99.1 20 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 28 d1hgxa_ not modelled 99.1 18 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 29 c2ywtA_ not modelled 99.1 19 PDB header:transferase Chain: A: PDB Molecule:hypoxanthine-guanine phosphoribosyltransferase; PDBTitle: crystal structure of hypoxanthine-guanine2 phosphoribosyltransferase with gmp from thermus3 thermophilus hb8 30 d1j7ja_ not modelled 99.1 18 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 31 d1g9sa_ not modelled 99.1 17 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 32 d1ecfa1 not modelled 98.9 15 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 33 d1u9ya2 not modelled 98.8 20 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosylpyrophosphate synthetase-like 34 c3lpnB_ not modelled 98.8 17 PDB header:transferase Chain: B: PDB Molecule:ribose-phosphate pyrophosphokinase; PDBTitle: crystal structure of the phosphoribosylpyrophosphate (prpp) synthetase2 from thermoplasma volcanium in complex with an atp analog (ampcpp). 35 d2c4ka2 not modelled 98.7 20 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosylpyrophosphate synthetase-like 36 d1dkua2 not modelled 98.7 17 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosylpyrophosphate synthetase-like 37 c3efhB_ not modelled 98.7 19 PDB header:transferase Chain: B: PDB Molecule:ribose-phosphate pyrophosphokinase 1; PDBTitle: crystal structure of human phosphoribosyl pyrophosphate2 synthetase 1 38 c2jkzB_ not modelled 98.7 16 PDB header:transferase Chain: B: PDB Molecule:hypoxanthine-guanine phosphoribosyltransferase; PDBTitle: saccharomyces cerevisiae hypoxanthine-guanine2 phosphoribosyltransferase in complex with gmp (guanosine 5'3 -monophosphate) (orthorhombic crystal form) 39 c1ecjB_ not modelled 98.7 12 PDB header:transferase Chain: B: PDB Molecule:glutamine phosphoribosylpyrophosphate PDBTitle: escherichia coli glutamine phosphoribosylpyrophosphate2 (prpp) amidotransferase complexed with 2 amp per tetramer 40 c2c4kD_ not modelled 98.6 19 PDB header:regulatory protein Chain: D: PDB Molecule:phosphoribosyl pyrophosphate synthetase- PDBTitle: crystal structure of human phosphoribosylpyrophosphate2 synthetase-associated protein 39 (pap39) 41 c1dkrB_ not modelled 98.6 17 PDB header:transferase Chain: B: PDB Molecule:phosphoribosyl pyrophosphate synthetase; PDBTitle: crystal structures of bacillus subtilis phosphoribosylpyrophosphate2 synthetase: molecular basis of allosteric inhibition and activation. 42 c1gph1_ not modelled 98.6 17 PDB header:transferase(glutamine amidotransferase) Chain: 1: PDB Molecule:glutamine phosphoribosyl-pyrophosphate amidotransferase; PDBTitle: structure of the allosteric regulatory enzyme of purine biosynthesis 43 d1zn7a1 not modelled 98.6 17 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 44 d1g2qa_ not modelled 98.6 17 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 45 d1gph11 not modelled 98.5 11 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 46 d1mzva_ not modelled 98.5 15 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 47 c1u9yD_ not modelled 98.5 25 PDB header:transferase Chain: D: PDB Molecule:ribose-phosphate pyrophosphokinase; PDBTitle: crystal structure of phosphoribosyl diphosphate synthase2 from methanocaldococcus jannaschii 48 d1y0ba1 not modelled 98.4 20 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 49 c3dahB_ not modelled 98.4 19 PDB header:transferase Chain: B: PDB Molecule:ribose-phosphate pyrophosphokinase; PDBTitle: 2.3 a crystal structure of ribose-phosphate pyrophosphokinase from2 burkholderia pseudomallei 50 c2dy0A_ not modelled 98.4 23 PDB header:transferase Chain: A: PDB Molecule:adenine phosphoribosyltransferase; PDBTitle: crystal structure of project jw0458 from escherichia coli 51 d1l1qa_ not modelled 98.3 23 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 52 d1vcha1 not modelled 98.3 12 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 53 c2p1zA_ not modelled 98.3 15 PDB header:transferase Chain: A: PDB Molecule:phosphoribosyltransferase; PDBTitle: crystal structure of phosphoribosyltransferase from corynebacterium2 diphtheriae 54 c2wnsB_ not modelled 98.2 18 PDB header:transferase Chain: B: PDB Molecule:orotate phosphoribosyltransferase; PDBTitle: human orotate phosphoribosyltransferase (oprtase) domain of2 uridine 5'-monophosphate synthase (umps) in complex with3 its substrate orotidine 5'-monophosphate (omp) 55 c2yzkC_ not modelled 98.2 23 PDB header:transferase Chain: C: PDB Molecule:orotate phosphoribosyltransferase; PDBTitle: crystal structure of orotate phosphoribosyltransferase from2 aeropyrum pernix 56 d1dqna_ not modelled 98.2 17 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 57 c3dezA_ not modelled 98.1 18 PDB header:transferase Chain: A: PDB Molecule:orotate phosphoribosyltransferase; PDBTitle: crystal structure of orotate phosphoribosyltransferase from2 streptococcus mutans 58 d1o57a2 not modelled 98.1 19 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 59 d2aeea1 not modelled 98.1 16 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 60 c1o57A_ not modelled 98.0 17 PDB header:dna binding protein Chain: A: PDB Molecule:pur operon repressor; PDBTitle: crystal structure of the purine operon repressor of2 bacillus subtilis 61 d1nula_ not modelled 98.0 16 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 62 d1lh0a_ not modelled 97.8 10 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 63 c3n2lA_ not modelled 97.8 15 PDB header:transferase Chain: A: PDB Molecule:orotate phosphoribosyltransferase; PDBTitle: 2.1 angstrom resolution crystal structure of an orotate2 phosphoribosyltransferase (pyre) from vibrio cholerae o1 biovar eltor3 str. n16961 64 c3m3hA_ not modelled 97.8 24 PDB header:transferase Chain: A: PDB Molecule:orotate phosphoribosyltransferase; PDBTitle: 1.75 angstrom resolution crystal structure of an orotate2 phosphoribosyltransferase from bacillus anthracis str. 'ames3 ancestor' 65 c3mjdA_ not modelled 97.7 10 PDB header:transferase Chain: A: PDB Molecule:orotate phosphoribosyltransferase; PDBTitle: 1.9 angstrom crystal structure of orotate2 phosphoribosyltransferase (pyre) francisella tularensis. 66 c2przB_ not modelled 97.7 10 PDB header:transferase Chain: B: PDB Molecule:orotate phosphoribosyltransferase 1; PDBTitle: s. cerevisiae orotate phosphoribosyltransferase complexed2 with omp 67 c3qw4B_ not modelled 95.9 25 PDB header:transferase, lyase Chain: B: PDB Molecule:ump synthase; PDBTitle: structure of leishmania donovani ump synthase 68 c3outC_ not modelled 89.2 17 PDB header:isomerase Chain: C: PDB Molecule:glutamate racemase; PDBTitle: crystal structure of glutamate racemase from francisella tularensis2 subsp. tularensis schu s4 in complex with d-glutamate. 69 d1b74a1 not modelled 89.1 21 Fold:ATC-like Superfamily:Aspartate/glutamate racemase Family:Aspartate/glutamate racemase 70 c2jfoB_ not modelled 89.0 18 PDB header:isomerase Chain: B: PDB Molecule:glutamate racemase; PDBTitle: crystal structure of enterococcus faecalis glutamate2 racemase in complex with d- and l-glutamate 71 c3hfrA_ not modelled 89.0 16 PDB header:isomerase Chain: A: PDB Molecule:glutamate racemase; PDBTitle: crystal structure of glutamate racemase from listeria monocytogenes 72 c2ohoA_ not modelled 89.0 18 PDB header:isomerase Chain: A: PDB Molecule:glutamate racemase; PDBTitle: structural basis for glutamate racemase inhibitor 73 c2jfqA_ not modelled 88.0 14 PDB header:isomerase Chain: A: PDB Molecule:glutamate racemase; PDBTitle: crystal structure of staphylococcus aureus glutamate2 racemase in complex with d-glutamate 74 d1u9ya1 not modelled 87.6 17 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosylpyrophosphate synthetase-like 75 c1b74A_ not modelled 87.3 21 PDB header:isomerase Chain: A: PDB Molecule:glutamate racemase; PDBTitle: glutamate racemase from aquifex pyrophilus 76 c2gzmB_ not modelled 87.0 15 PDB header:isomerase Chain: B: PDB Molecule:glutamate racemase; PDBTitle: crystal structure of the glutamate racemase from bacillus2 anthracis 77 d2c4ka1 not modelled 85.5 10 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosylpyrophosphate synthetase-like 78 c2dwuA_ not modelled 84.3 24 PDB header:isomerase Chain: A: PDB Molecule:glutamate racemase; PDBTitle: crystal structure of glutamate racemase isoform race1 from bacillus2 anthracis 79 c3pwzA_ not modelled 82.2 19 PDB header:oxidoreductase Chain: A: PDB Molecule:shikimate dehydrogenase 3; PDBTitle: crystal structure of an ael1 enzyme from pseudomonas putida 80 d1dkua1 not modelled 77.6 15 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosylpyrophosphate synthetase-like 81 c3pgjB_ not modelled 77.4 16 PDB header:oxidoreductase Chain: B: PDB Molecule:shikimate dehydrogenase; PDBTitle: 2.49 angstrom resolution crystal structure of shikimate 5-2 dehydrogenase (aroe) from vibrio cholerae o1 biovar eltor str. n169613 in complex with shikimate 82 d1vi2a1 not modelled 77.1 20 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Aminoacid dehydrogenase-like, C-terminal domain 83 c1zuwA_ not modelled 76.1 14 PDB header:isomerase Chain: A: PDB Molecule:glutamate racemase 1; PDBTitle: crystal structure of b.subtilis glutamate racemase (race) with d-glu 84 c3u7jA_ not modelled 75.4 25 PDB header:isomerase Chain: A: PDB Molecule:ribose-5-phosphate isomerase a; PDBTitle: crystal structure of ribose-5-phosphate isomerase a from burkholderia2 thailandensis 85 c3o8qB_ not modelled 75.0 16 PDB header:oxidoreductase Chain: B: PDB Molecule:shikimate 5-dehydrogenase i alpha; PDBTitle: 1.45 angstrom resolution crystal structure of shikimate 5-2 dehydrogenase (aroe) from vibrio cholerae 86 c2jfnA_ not modelled 74.7 20 PDB header:isomerase Chain: A: PDB Molecule:glutamate racemase; PDBTitle: crystal structure of escherichia coli glutamate racemase2 in complex with l-glutamate and activator udp-murnac-ala 87 c2jfzB_ not modelled 74.5 18 PDB header:isomerase Chain: B: PDB Molecule:glutamate racemase; PDBTitle: crystal structure of helicobacter pylori glutamate racemase2 in complex with d-glutamate and an inhibitor 88 d1o8bb1 not modelled 73.3 22 Fold:NagB/RpiA/CoA transferase-like Superfamily:NagB/RpiA/CoA transferase-like Family:D-ribose-5-phosphate isomerase (RpiA), catalytic domain 89 c3ca8B_ not modelled 72.9 19 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:protein ydcf; PDBTitle: crystal structure of escherichia coli ydcf, an s-adenosyl-l-methionine2 utilizing enzyme 90 d1npya1 not modelled 66.5 16 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Aminoacid dehydrogenase-like, C-terminal domain 91 c2pjmA_ not modelled 63.7 19 PDB header:isomerase Chain: A: PDB Molecule:ribose-5-phosphate isomerase a; PDBTitle: structure of ribose 5-phosphate isomerase a from2 methanocaldococcus jannaschii 92 c2eggA_ not modelled 60.4 15 PDB header:oxidoreductase Chain: A: PDB Molecule:shikimate 5-dehydrogenase; PDBTitle: crystal structure of shikimate 5-dehydrogenase (aroe) from2 geobacillus kaustophilus 93 c3fbtB_ not modelled 60.3 29 PDB header:oxidoreductase, lyase Chain: B: PDB Molecule:chorismate mutase and shikimate 5-dehydrogenase PDBTitle: crystal structure of a chorismate mutase/shikimate 5-2 dehydrogenase fusion protein from clostridium3 acetobutylicum 94 d3beda1 not modelled 59.3 10 Fold:PTS system fructose IIA component-like Superfamily:PTS system fructose IIA component-like Family:EIIA-man component-like 95 c3tozA_ not modelled 56.1 17 PDB header:oxidoreductase Chain: A: PDB Molecule:shikimate dehydrogenase; PDBTitle: 2.2 angstrom crystal structure of shikimate 5-dehydrogenase from2 listeria monocytogenes in complex with nad. 96 d1p77a1 not modelled 55.5 17 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Aminoacid dehydrogenase-like, C-terminal domain 97 c3k13A_ not modelled 52.8 21 PDB header:transferase Chain: A: PDB Molecule:5-methyltetrahydrofolate-homocysteine methyltransferase; PDBTitle: structure of the pterin-binding domain metr of 5-2 methyltetrahydrofolate-homocysteine methyltransferase from3 bacteroides thetaiotaomicron 98 d2e7ya1 not modelled 51.6 18 Fold:Metallo-hydrolase/oxidoreductase Superfamily:Metallo-hydrolase/oxidoreductase Family:RNase Z-like 99 d2fwra2 not modelled 49.6 12 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Tandem AAA-ATPase domain 100 c1npyA_ not modelled 49.2 16 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical shikimate 5-dehydrogenase-like PDBTitle: structure of shikimate 5-dehydrogenase-like protein hi0607 101 d1qh5a_ not modelled 47.6 25 Fold:Metallo-hydrolase/oxidoreductase Superfamily:Metallo-hydrolase/oxidoreductase Family:Glyoxalase II (hydroxyacylglutathione hydrolase) 102 c1lkzB_ not modelled 46.6 21 PDB header:isomerase Chain: B: PDB Molecule:ribose 5-phosphate isomerase a; PDBTitle: crystal structure of d-ribose-5-phosphate isomerase (rpia)2 from escherichia coli. 103 c1xtzA_ not modelled 44.3 13 PDB header:isomerase Chain: A: PDB Molecule:ribose-5-phosphate isomerase; PDBTitle: crystal structure of the s. cerevisiae d-ribose-5-phosphate isomerase:2 comparison with the archeal and bacterial enzymes 104 d1g60a_ not modelled 43.5 22 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Type II DNA methylase 105 c1vi2B_ not modelled 43.4 23 PDB header:oxidoreductase Chain: B: PDB Molecule:shikimate 5-dehydrogenase 2; PDBTitle: crystal structure of shikimate-5-dehydrogenase with nad 106 c2ohiB_ not modelled 42.7 11 PDB header:oxidoreductase Chain: B: PDB Molecule:type a flavoprotein fpra; PDBTitle: crystal structure of coenzyme f420h2 oxidase (fpra), a diiron2 flavoprotein, reduced state 107 c3kwmC_ not modelled 40.7 22 PDB header:isomerase Chain: C: PDB Molecule:ribose-5-phosphate isomerase a; PDBTitle: crystal structure of ribose-5-isomerase a 108 c3hnnD_ not modelled 40.3 17 PDB header:oxidoreductase Chain: D: PDB Molecule:putative diflavin flavoprotein a 5; PDBTitle: crystal structure of putative diflavin flavoprotein a 5 (fragment 1-2 254) from nostoc sp. pcc 7120, northeast structural genomics3 consortium target nsr435a 109 c1vliA_ not modelled 40.3 27 PDB header:biosynthetic protein Chain: A: PDB Molecule:spore coat polysaccharide biosynthesis protein spse; PDBTitle: crystal structure of spore coat polysaccharide biosynthesis protein2 spse (bsu37870) from bacillus subtilis at 2.38 a resolution 110 c2zifB_ not modelled 39.7 20 PDB header:transferase Chain: B: PDB Molecule:putative modification methylase; PDBTitle: crystal structure of ttha0409, putative dna modification2 methylase from thermus thermophilus hb8- complexed with s-3 adenosyl-l-methionine 111 d2q0ia1 not modelled 39.6 12 Fold:Metallo-hydrolase/oxidoreductase Superfamily:Metallo-hydrolase/oxidoreductase Family:PqsE-like 112 d1eg2a_ not modelled 38.5 16 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Type II DNA methylase 113 c3tbkA_ not modelled 37.7 14 PDB header:hydrolase Chain: A: PDB Molecule:rig-i helicase domain; PDBTitle: mouse rig-i atpase domain 114 c1nw6A_ not modelled 36.3 17 PDB header:transferase Chain: A: PDB Molecule:modification methylase rsri; PDBTitle: structure of the beta class n6-adenine dna methyltransferase rsri2 bound to sinefungin 115 c2hk8B_ not modelled 35.8 27 PDB header:oxidoreductase Chain: B: PDB Molecule:shikimate dehydrogenase; PDBTitle: crystal structure of shikimate dehydrogenase from aquifex2 aeolicus at 2.35 angstrom resolution 116 d1f8fa1 not modelled 34.8 16 Fold:GroES-like Superfamily:GroES-like Family:Alcohol dehydrogenase-like, N-terminal domain 117 c3hzhA_ not modelled 34.5 15 PDB header:signaling protein Chain: A: PDB Molecule:chemotaxis response regulator (chey-3); PDBTitle: crystal structure of the chex-chey-bef3-mg+2 complex from2 borrelia burgdorferi 118 c3donA_ not modelled 34.5 25 PDB header:oxidoreductase Chain: A: PDB Molecule:shikimate dehydrogenase; PDBTitle: crystal structure of shikimate dehydrogenase from staphylococcus2 epidermidis 119 c2qkxA_ not modelled 34.4 17 PDB header:transferase Chain: A: PDB Molecule:bifunctional protein glmu; PDBTitle: n-acetyl glucosamine 1-phosphate uridyltransferase from mycobacterium2 tuberculosis complex with n-acetyl glucosamine 1-phosphate 120 d1e5da2 not modelled 32.2 14 Fold:Metallo-hydrolase/oxidoreductase Superfamily:Metallo-hydrolase/oxidoreductase Family:ROO N-terminal domain-like

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0