PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c2hk8B_

Fold library id	PDB Header	Molecule	Title
c2hk8B_	PDB header: oxidoreductase	Chain: B: PDB Molecule: shikimate dehydrogenase;	PDBTitle: crystal structure of shikimate dehydrogenase from aquifex2 aeolicus at 2.35 angstrom resolution

Links to external resources
Added to library: Tue Mar 16 13:57:46 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence M I N A Q T Q L Y G V I G F P V K H S L S P V F Q N A L I R Y A G L N A V Y L A F E I N P E E L K K A F E G F K A L K V K G I N V T V P F K

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T
S S
T T
S T
S
G G G T T
T T
T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence E E I I P L L D Y V E D T A K E I G A V N T V K F E N G K A Y G Y N T D W I G F L K S L K S L I P E V K E K S I L V L G A G G A S R A V I Y

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T G G G
S
T
T T
T T T
S
T T
S

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence A L V K E G A K V F L W N R T K E K A I K L A Q K F P L E V V N S P E E V I D K V Q V I V N T T S V G L K D E D P E I F N Y D L I K K D H V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T
S S S
S
G G G T G G G
S
S S T T S S T T
S S
G G G
T T

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . . 260 . . . . . .

Sequence V V D I I Y K E T K L L K K A K E K G A K L L D G L P M L L W Q G I E A F K I W N G C E V P Y S V A E R S V R D

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S S
T T
S S

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

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Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	M	I	N	A	Q	T	Q	L	Y	G	V	I	G	F	P	V	K	H	S	L	S	P	V	F	Q	N	A	L	I	R	Y	A	G	L	N	A	V	Y	L	A	F	E	I	N	P	E	E	L	K	K	A	F	E	G	F	K	A	L	K	V	K	G	I	N	V	T	V	P	F	K
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				T	T									S	S		T	T		S													T		S										G	G	G											T	T								T	T		T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	E	E	I	I	P	L	L	D	Y	V	E	D	T	A	K	E	I	G	A	V	N	T	V	K	F	E	N	G	K	A	Y	G	Y	N	T	D	W	I	G	F	L	K	S	L	K	S	L	I	P	E	V	K	E	K	S	I	L	V	L	G	A	G	G	A	S	R	A	V	I	Y
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	T	T	G	G	G		S										T									T	T																	T	T	T		S			T	T									S
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	A	L	V	K	E	G	A	K	V	F	L	W	N	R	T	K	E	K	A	I	K	L	A	Q	K	F	P	L	E	V	V	N	S	P	E	E	V	I	D	K	V	Q	V	I	V	N	T	T	S	V	G	L	K	D	E	D	P	E	I	F	N	Y	D	L	I	K	K	D	H	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)					T	T								S	S											S						S		G	G	G	T	G	G	G		S						S	S	T	T	S	S	T	T				S	S		G	G	G			T	T
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.
Sequence	V	V	D	I	I	Y	K	E	T	K	L	L	K	K	A	K	E	K	G	A	K	L	L	D	G	L	P	M	L	L	W	Q	G	I	E	A	F	K	I	W	N	G	C	E	V	P	Y	S	V	A	E	R	S	V	R	D
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)					S	S	S											T	T						S																	S