Phyre 2 Results for P0A8F0

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Email | l.a.kelley@imperial.ac.uk
Description | P0A8F0
Date | Wed Jan 25 15:20:18 GMT 2012
Unique Job ID | 604bb1607b53aede

Summary |

Top model
Image coloured by rainbow N → C terminus
| Close Jmol

Model (left) based on template d1i5ea_
Top template information
Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases)
Confidence and coverage
Confidence: | 100.0% | Coverage: | 100%
207 residues (100% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis |

Secondary structure and disorder prediction |

|  | 1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60
Sequence |  | M | K | I | V | E | V | K | H | P | L | V | K | H | K | L | G | L | M | R | E | Q | D | I | S | T | K | R | F | R | E | L | A | S | E | V | G | S | L | L | T | Y | E | A | T | A | D | L | E | T | E | K | V | T | I | E | G | W | N | G | P
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? |  |  |  | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120
Sequence |  | V | E | I | D | Q | I | K | G | K | K | I | T | V | V | P | I | L | R | A | G | L | G | M | M | D | G | V | L | E | N | V | P | S | A | R | I | S | V | V | G | M | Y | R | N | E | E | T | L | E | P | V | P | Y | F | Q | K | L | V | S | N
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180
Sequence |  | I | D | E | R | M | A | L | I | V | D | P | M | L | A | T | G | G | S | V | I | A | T | I | D | L | L | K | K | A | G | C | S | S | I | K | V | L | V | L | V | A | A | P | E | G | I | A | A | L | E | K | A | H | P | D | V | E | L | Y | T
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | .
Sequence |  | A | S | I | D | Q | G | L | N | E | H | G | Y | I | I | P | G | L | G | D | A | G | D | K | I | F | G | T | K
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |

Confidence Key
High(9) |  |  |  |  |  |  |  |  |  |  | Low (0)

? | Disordered
| Alpha helix
| Beta strand

Domain analysis |

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank | Aligned region
--- | ---
1 |
| d1i5ea_ |

### PDB 1i5e chain A

Region: 2 - 208
Aligned: 207
Modelled: 207
Confidence: 100.0%
Identity: 54%
Fold: PRTase-like
Superfamily: PRTase-like
Family: Phosphoribosyltransferases (PRTases)

Phyre2
2 |
| c2ehjA_ |

### PDB 2ehj chain A

Region: 2 - 208
Aligned: 207
Modelled: 207
Confidence: 100.0%
Identity: 100%
PDB header:transferase
Chain: A: PDB Molecule:uracil phosphoribosyltransferase;
PDBTitle: structure of uracil phosphoribosyl transferase

Phyre2
3 |
| d1o5oa_ |

### PDB 1o5o chain A

Region: 2 - 208
Aligned: 207
Modelled: 207
Confidence: 100.0%
Identity: 50%
Fold: PRTase-like
Superfamily: PRTase-like
Family: Phosphoribosyltransferases (PRTases)

Phyre2
4 |
| d1bd3a_ |

### PDB 1bd3 chain A

Region: 2 - 207
Aligned: 206
Modelled: 206
Confidence: 100.0%
Identity: 33%
Fold: PRTase-like
Superfamily: PRTase-like
Family: Phosphoribosyltransferases (PRTases)

Phyre2
5 |
| c2e55D_ |

### PDB 2e55 chain D

Region: 3 - 208
Aligned: 205
Modelled: 206
Confidence: 100.0%
Identity: 40%
PDB header:transferase
Chain: D: PDB Molecule:uracil phosphoribosyltransferase;
PDBTitle: structure of aq2163 protein from aquifex aeolicus

Phyre2
6 |
| c3dmpD_ |

### PDB 3dmp chain D

Region: 2 - 206
Aligned: 203
Modelled: 205
Confidence: 100.0%
Identity: 46%
PDB header:transferase
Chain: D: PDB Molecule:uracil phosphoribosyltransferase;
PDBTitle: 2.6 a crystal structure of uracil phosphoribosyltransferase2 from burkholderia pseudomallei

Phyre2
7 |
| d1v9sa1 |

### PDB 1v9s chain A domain 1

Region: 1 - 208
Aligned: 199
Modelled: 207
Confidence: 100.0%
Identity: 49%
Fold: PRTase-like
Superfamily: PRTase-like
Family: Phosphoribosyltransferases (PRTases)

Phyre2
8 |
| d1xtta1 |

### PDB 1xtt chain A domain 1

Region: 2 - 206
Aligned: 205
Modelled: 205
Confidence: 100.0%
Identity: 30%
Fold: PRTase-like
Superfamily: PRTase-like
Family: Phosphoribosyltransferases (PRTases)

Phyre2
9 |
| d1qb7a_ |

### PDB 1qb7 chain A

Region: 72 - 207
Aligned: 136
Modelled: 136
Confidence: 99.9%
Identity: 14%
Fold: PRTase-like
Superfamily: PRTase-like
Family: Phosphoribosyltransferases (PRTases)

Phyre2
10 |
| c1yfzA_ |

### PDB 1yfz chain A

Region: 24 - 205
Aligned: 155
Modelled: 159
Confidence: 99.4%
Identity: 16%
PDB header:transferase
Chain: A: PDB Molecule:hypoxanthine-guanine phosphoribosyltransferase;
PDBTitle: novel imp binding in feedback inhibition of hypoxanthine-guanine2 phosphoribosyltransferase from thermoanaerobacter tengcongensis

Phyre2
11 |
| d1yfza1 |

### PDB 1yfz chain A domain 1

Region: 24 - 205
Aligned: 155
Modelled: 159
Confidence: 99.4%
Identity: 16%
Fold: PRTase-like
Superfamily: PRTase-like
Family: Phosphoribosyltransferases (PRTases)

Phyre2
12 |
| c3kb8A_ |

### PDB 3kb8 chain A

Region: 24 - 165
Aligned: 119
Modelled: 119
Confidence: 99.3%
Identity: 20%
PDB header:transferase
Chain: A: PDB Molecule:hypoxanthine phosphoribosyltransferase;
PDBTitle: 2.09 angstrom resolution structure of a hypoxanthine-guanine2 phosphoribosyltransferase (hpt-1) from bacillus anthracis str. 'ames3 ancestor' in complex with gmp

Phyre2
13 |
| d1p17b_ |

### PDB 1p17 chain B

Region: 24 - 165
Aligned: 126
Modelled: 126
Confidence: 99.3%
Identity: 15%
Fold: PRTase-like
Superfamily: PRTase-like
Family: Phosphoribosyltransferases (PRTases)

Phyre2
14 |
| d1wd5a_ |

### PDB 1wd5 chain A

Region: 65 - 185
Aligned: 118
Modelled: 121
Confidence: 99.3%
Identity: 23%
Fold: PRTase-like
Superfamily: PRTase-like
Family: Phosphoribosyltransferases (PRTases)

Phyre2
15 |
| d1tc1a_ |

### PDB 1tc1 chain A

Region: 24 - 165
Aligned: 124
Modelled: 126
Confidence: 99.3%
Identity: 15%
Fold: PRTase-like
Superfamily: PRTase-like
Family: Phosphoribosyltransferases (PRTases)

Phyre2
16 |
| d2igba1 |

### PDB 2igb chain A domain 1

Region: 24 - 160
Aligned: 115
Modelled: 115
Confidence: 99.3%
Identity: 21%
Fold: PRTase-like
Superfamily: PRTase-like
Family: Phosphoribosyltransferases (PRTases)

Phyre2
17 |
| d1cjba_ |

### PDB 1cjb chain A

Region: 24 - 160
Aligned: 114
Modelled: 114
Confidence: 99.3%
Identity: 16%
Fold: PRTase-like
Superfamily: PRTase-like
Family: Phosphoribosyltransferases (PRTases)

Phyre2
18 |
| d1a3ca_ |

### PDB 1a3c chain A

Region: 24 - 160
Aligned: 110
Modelled: 111
Confidence: 99.2%
Identity: 24%
Fold: PRTase-like
Superfamily: PRTase-like
Family: Phosphoribosyltransferases (PRTases)

Phyre2
19 |
| d1z7ga1 |

### PDB 1z7g chain A domain 1

Region: 24 - 160
Aligned: 114
Modelled: 114
Confidence: 99.2%
Identity: 17%
Fold: PRTase-like
Superfamily: PRTase-like
Family: Phosphoribosyltransferases (PRTases)

Phyre2
20 |
| c1pzmB_ |

### PDB 1pzm chain B

Region: 24 - 165
Aligned: 120
Modelled: 125
Confidence: 99.2%
Identity: 11%
PDB header:transferase
Chain: B: PDB Molecule:hypoxanthine-guanine phosphoribosyltransferase;
PDBTitle: crystal structure of hgprt-ase from leishmania tarentolae in complex2 with gmp

Phyre2
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Detailed template information |

# | Template | Alignment Coverage | 3D Model | Confidence | % i.d. | Template Information
--- | --- | --- | --- | --- | --- | ---
1 | d1i5ea_ |
|  | 100.0 | 54 | Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases)
2 | c2ehjA_ |
|  | 100.0 | 100 | PDB header:transferase Chain: A: PDB Molecule:uracil phosphoribosyltransferase; PDBTitle: structure of uracil phosphoribosyl transferase
3 | d1o5oa_ |
|  | 100.0 | 50 | Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases)
4 | d1bd3a_ |
|  | 100.0 | 33 | Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases)
5 | c2e55D_ |
|  | 100.0 | 40 | PDB header:transferase Chain: D: PDB Molecule:uracil phosphoribosyltransferase; PDBTitle: structure of aq2163 protein from aquifex aeolicus
6 | c3dmpD_ |
|  | 100.0 | 46 | PDB header:transferase Chain: D: PDB Molecule:uracil phosphoribosyltransferase; PDBTitle: 2.6 a crystal structure of uracil phosphoribosyltransferase2 from burkholderia pseudomallei
7 | d1v9sa1 |
|  | 100.0 | 49 | Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases)
8 | d1xtta1 |
|  | 100.0 | 30 | Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases)
9 | d1qb7a_ |
|  | 99.9 | 14 | Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases)
10 | c1yfzA_ |
|  | 99.4 | 16 | PDB header:transferase Chain: A: PDB Molecule:hypoxanthine-guanine phosphoribosyltransferase; PDBTitle: novel imp binding in feedback inhibition of hypoxanthine-guanine2 phosphoribosyltransferase from thermoanaerobacter tengcongensis
11 | d1yfza1 |
|  | 99.4 | 16 | Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases)
12 | c3kb8A_ |
|  | 99.3 | 20 | PDB header:transferase Chain: A: PDB Molecule:hypoxanthine phosphoribosyltransferase; PDBTitle: 2.09 angstrom resolution structure of a hypoxanthine-guanine2 phosphoribosyltransferase (hpt-1) from bacillus anthracis str. 'ames3 ancestor' in complex with gmp
13 | d1p17b_ |
|  | 99.3 | 15 | Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases)
14 | d1wd5a_ |
|  | 99.3 | 23 | Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases)
15 | d1tc1a_ |
|  | 99.3 | 15 | Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases)
16 | d2igba1 |
|  | 99.3 | 21 | Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases)
17 | d1cjba_ |
|  | 99.3 | 16 | Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases)
18 | d1a3ca_ |
|  | 99.2 | 24 | Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases)
19 | d1z7ga1 |
|  | 99.2 | 17 | Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases)
20 | c1pzmB_ |
|  | 99.2 | 11 | PDB header:transferase Chain: B: PDB Molecule:hypoxanthine-guanine phosphoribosyltransferase; PDBTitle: crystal structure of hgprt-ase from leishmania tarentolae in complex2 with gmp
21 | c2jbhA_ |
| not modelled | 99.2 | 21 | PDB header:transferase Chain: A: PDB Molecule:phosphoribosyltransferase domain-containing protein 1; PDBTitle: human phosphoribosyl transferase domain containing 1
22 | d1fsga_ |
| not modelled | 99.2 | 18 | Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases)
23 | d1ufra_ |
| not modelled | 99.2 | 19 | Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases)
24 | d1pzma_ |
| not modelled | 99.2 | 10 | Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases)
25 | d1vdma1 |
| not modelled | 99.2 | 21 | Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases)
26 | c3o7mD_ |
| not modelled | 99.2 | 17 | PDB header:transferase Chain: D: PDB Molecule:hypoxanthine phosphoribosyltransferase; PDBTitle: 1.98 angstrom resolution crystal structure of a hypoxanthine-guanine2 phosphoribosyltransferase (hpt-2) from bacillus anthracis str. 'ames3 ancestor'
27 | d1w30a_ |
| not modelled | 99.1 | 20 | Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases)
28 | d1hgxa_ |
| not modelled | 99.1 | 18 | Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases)
29 | c2ywtA_ |
| not modelled | 99.1 | 19 | PDB header:transferase Chain: A: PDB Molecule:hypoxanthine-guanine phosphoribosyltransferase; PDBTitle: crystal structure of hypoxanthine-guanine2 phosphoribosyltransferase with gmp from thermus3 thermophilus hb8
30 | d1j7ja_ |
| not modelled | 99.1 | 18 | Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases)
31 | d1g9sa_ |
| not modelled | 99.1 | 17 | Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases)
32 | d1ecfa1 |
| not modelled | 98.9 | 15 | Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases)
33 | d1u9ya2 |
| not modelled | 98.8 | 20 | Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosylpyrophosphate synthetase-like
34 | c3lpnB_ |
| not modelled | 98.8 | 17 | PDB header:transferase Chain: B: PDB Molecule:ribose-phosphate pyrophosphokinase; PDBTitle: crystal structure of the phosphoribosylpyrophosphate (prpp) synthetase2 from thermoplasma volcanium in complex with an atp analog (ampcpp).
35 | d2c4ka2 |
| not modelled | 98.7 | 20 | Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosylpyrophosphate synthetase-like
36 | d1dkua2 |
| not modelled | 98.7 | 17 | Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosylpyrophosphate synthetase-like
37 | c3efhB_ |
| not modelled | 98.7 | 19 | PDB header:transferase Chain: B: PDB Molecule:ribose-phosphate pyrophosphokinase 1; PDBTitle: crystal structure of human phosphoribosyl pyrophosphate2 synthetase 1
38 | c2jkzB_ |
| not modelled | 98.7 | 16 | PDB header:transferase Chain: B: PDB Molecule:hypoxanthine-guanine phosphoribosyltransferase; PDBTitle: saccharomyces cerevisiae hypoxanthine-guanine2 phosphoribosyltransferase in complex with gmp (guanosine 5'3 -monophosphate) (orthorhombic crystal form)
39 | c1ecjB_ |
| not modelled | 98.7 | 12 | PDB header:transferase Chain: B: PDB Molecule:glutamine phosphoribosylpyrophosphate PDBTitle: escherichia coli glutamine phosphoribosylpyrophosphate2 (prpp) amidotransferase complexed with 2 amp per tetramer
40 | c2c4kD_ |
| not modelled | 98.6 | 19 | PDB header:regulatory protein Chain: D: PDB Molecule:phosphoribosyl pyrophosphate synthetase- PDBTitle: crystal structure of human phosphoribosylpyrophosphate2 synthetase-associated protein 39 (pap39)
41 | c1dkrB_ |
| not modelled | 98.6 | 17 | PDB header:transferase Chain: B: PDB Molecule:phosphoribosyl pyrophosphate synthetase; PDBTitle: crystal structures of bacillus subtilis phosphoribosylpyrophosphate2 synthetase: molecular basis of allosteric inhibition and activation.
42 | c1gph1_ |
| not modelled | 98.6 | 17 | PDB header:transferase(glutamine amidotransferase) Chain: 1: PDB Molecule:glutamine phosphoribosyl-pyrophosphate amidotransferase; PDBTitle: structure of the allosteric regulatory enzyme of purine biosynthesis
43 | d1zn7a1 |
| not modelled | 98.6 | 17 | Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases)
44 | d1g2qa_ |
| not modelled | 98.6 | 17 | Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases)
45 | d1gph11 |
| not modelled | 98.5 | 11 | Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases)
46 | d1mzva_ |
| not modelled | 98.5 | 15 | Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases)
47 | c1u9yD_ |
| not modelled | 98.5 | 25 | PDB header:transferase Chain: D: PDB Molecule:ribose-phosphate pyrophosphokinase; PDBTitle: crystal structure of phosphoribosyl diphosphate synthase2 from methanocaldococcus jannaschii
48 | d1y0ba1 |
| not modelled | 98.4 | 20 | Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases)
49 | c3dahB_ |
| not modelled | 98.4 | 19 | PDB header:transferase Chain: B: PDB Molecule:ribose-phosphate pyrophosphokinase; PDBTitle: 2.3 a crystal structure of ribose-phosphate pyrophosphokinase from2 burkholderia pseudomallei
50 | c2dy0A_ |
| not modelled | 98.4 | 23 | PDB header:transferase Chain: A: PDB Molecule:adenine phosphoribosyltransferase; PDBTitle: crystal structure of project jw0458 from escherichia coli
51 | d1l1qa_ |
| not modelled | 98.3 | 23 | Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases)
52 | d1vcha1 |
| not modelled | 98.3 | 12 | Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases)
53 | c2p1zA_ |
| not modelled | 98.3 | 15 | PDB header:transferase Chain: A: PDB Molecule:phosphoribosyltransferase; PDBTitle: crystal structure of phosphoribosyltransferase from corynebacterium2 diphtheriae
54 | c2wnsB_ |
| not modelled | 98.2 | 18 | PDB header:transferase Chain: B: PDB Molecule:orotate phosphoribosyltransferase; PDBTitle: human orotate phosphoribosyltransferase (oprtase) domain of2 uridine 5'-monophosphate synthase (umps) in complex with3 its substrate orotidine 5'-monophosphate (omp)
55 | c2yzkC_ |
| not modelled | 98.2 | 23 | PDB header:transferase Chain: C: PDB Molecule:orotate phosphoribosyltransferase; PDBTitle: crystal structure of orotate phosphoribosyltransferase from2 aeropyrum pernix
56 | d1dqna_ |
| not modelled | 98.2 | 17 | Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases)
57 | c3dezA_ |
| not modelled | 98.1 | 18 | PDB header:transferase Chain: A: PDB Molecule:orotate phosphoribosyltransferase; PDBTitle: crystal structure of orotate phosphoribosyltransferase from2 streptococcus mutans
58 | d1o57a2 |
| not modelled | 98.1 | 19 | Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases)
59 | d2aeea1 |
| not modelled | 98.1 | 16 | Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases)
60 | c1o57A_ |
| not modelled | 98.0 | 17 | PDB header:dna binding protein Chain: A: PDB Molecule:pur operon repressor; PDBTitle: crystal structure of the purine operon repressor of2 bacillus subtilis
61 | d1nula_ |
| not modelled | 98.0 | 16 | Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases)
62 | d1lh0a_ |
| not modelled | 97.8 | 10 | Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases)
63 | c3n2lA_ |
| not modelled | 97.8 | 15 | PDB header:transferase Chain: A: PDB Molecule:orotate phosphoribosyltransferase; PDBTitle: 2.1 angstrom resolution crystal structure of an orotate2 phosphoribosyltransferase (pyre) from vibrio cholerae o1 biovar eltor3 str. n16961
64 | c3m3hA_ |
| not modelled | 97.8 | 24 | PDB header:transferase Chain: A: PDB Molecule:orotate phosphoribosyltransferase; PDBTitle: 1.75 angstrom resolution crystal structure of an orotate2 phosphoribosyltransferase from bacillus anthracis str. 'ames3 ancestor'
65 | c3mjdA_ |
| not modelled | 97.7 | 10 | PDB header:transferase Chain: A: PDB Molecule:orotate phosphoribosyltransferase; PDBTitle: 1.9 angstrom crystal structure of orotate2 phosphoribosyltransferase (pyre) francisella tularensis.
66 | c2przB_ |
| not modelled | 97.7 | 10 | PDB header:transferase Chain: B: PDB Molecule:orotate phosphoribosyltransferase 1; PDBTitle: s. cerevisiae orotate phosphoribosyltransferase complexed2 with omp
67 | c3qw4B_ |
| not modelled | 95.9 | 25 | PDB header:transferase, lyase Chain: B: PDB Molecule:ump synthase; PDBTitle: structure of leishmania donovani ump synthase
68 | c3outC_ |
| not modelled | 89.2 | 17 | PDB header:isomerase Chain: C: PDB Molecule:glutamate racemase; PDBTitle: crystal structure of glutamate racemase from francisella tularensis2 subsp. tularensis schu s4 in complex with d-glutamate.
69 | d1b74a1 |
| not modelled | 89.1 | 21 | Fold:ATC-like Superfamily:Aspartate/glutamate racemase Family:Aspartate/glutamate racemase
70 | c2jfoB_ |
| not modelled | 89.0 | 18 | PDB header:isomerase Chain: B: PDB Molecule:glutamate racemase; PDBTitle: crystal structure of enterococcus faecalis glutamate2 racemase in complex with d- and l-glutamate
71 | c3hfrA_ |
| not modelled | 89.0 | 16 | PDB header:isomerase Chain: A: PDB Molecule:glutamate racemase; PDBTitle: crystal structure of glutamate racemase from listeria monocytogenes
72 | c2ohoA_ |
| not modelled | 89.0 | 18 | PDB header:isomerase Chain: A: PDB Molecule:glutamate racemase; PDBTitle: structural basis for glutamate racemase inhibitor
73 | c2jfqA_ |
| not modelled | 88.0 | 14 | PDB header:isomerase Chain: A: PDB Molecule:glutamate racemase; PDBTitle: crystal structure of staphylococcus aureus glutamate2 racemase in complex with d-glutamate
74 | d1u9ya1 |
| not modelled | 87.6 | 17 | Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosylpyrophosphate synthetase-like
75 | c1b74A_ |
| not modelled | 87.3 | 21 | PDB header:isomerase Chain: A: PDB Molecule:glutamate racemase; PDBTitle: glutamate racemase from aquifex pyrophilus
76 | c2gzmB_ |
| not modelled | 87.0 | 15 | PDB header:isomerase Chain: B: PDB Molecule:glutamate racemase; PDBTitle: crystal structure of the glutamate racemase from bacillus2 anthracis
77 | d2c4ka1 |
| not modelled | 85.5 | 10 | Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosylpyrophosphate synthetase-like
78 | c2dwuA_ |
| not modelled | 84.3 | 24 | PDB header:isomerase Chain: A: PDB Molecule:glutamate racemase; PDBTitle: crystal structure of glutamate racemase isoform race1 from bacillus2 anthracis
79 | c3pwzA_ |
| not modelled | 82.2 | 19 | PDB header:oxidoreductase Chain: A: PDB Molecule:shikimate dehydrogenase 3; PDBTitle: crystal structure of an ael1 enzyme from pseudomonas putida
80 | d1dkua1 |
| not modelled | 77.6 | 15 | Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosylpyrophosphate synthetase-like
81 | c3pgjB_ |
| not modelled | 77.4 | 16 | PDB header:oxidoreductase Chain: B: PDB Molecule:shikimate dehydrogenase; PDBTitle: 2.49 angstrom resolution crystal structure of shikimate 5-2 dehydrogenase (aroe) from vibrio cholerae o1 biovar eltor str. n169613 in complex with shikimate
82 | d1vi2a1 |
| not modelled | 77.1 | 20 | Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Aminoacid dehydrogenase-like, C-terminal domain
83 | c1zuwA_ |
| not modelled | 76.1 | 14 | PDB header:isomerase Chain: A: PDB Molecule:glutamate racemase 1; PDBTitle: crystal structure of b.subtilis glutamate racemase (race) with d-glu
84 | c3u7jA_ |
| not modelled | 75.4 | 25 | PDB header:isomerase Chain: A: PDB Molecule:ribose-5-phosphate isomerase a; PDBTitle: crystal structure of ribose-5-phosphate isomerase a from burkholderia2 thailandensis
85 | c3o8qB_ |
| not modelled | 75.0 | 16 | PDB header:oxidoreductase Chain: B: PDB Molecule:shikimate 5-dehydrogenase i alpha; PDBTitle: 1.45 angstrom resolution crystal structure of shikimate 5-2 dehydrogenase (aroe) from vibrio cholerae
86 | c2jfnA_ |
| not modelled | 74.7 | 20 | PDB header:isomerase Chain: A: PDB Molecule:glutamate racemase; PDBTitle: crystal structure of escherichia coli glutamate racemase2 in complex with l-glutamate and activator udp-murnac-ala
87 | c2jfzB_ |
| not modelled | 74.5 | 18 | PDB header:isomerase Chain: B: PDB Molecule:glutamate racemase; PDBTitle: crystal structure of helicobacter pylori glutamate racemase2 in complex with d-glutamate and an inhibitor
88 | d1o8bb1 |
| not modelled | 73.3 | 22 | Fold:NagB/RpiA/CoA transferase-like Superfamily:NagB/RpiA/CoA transferase-like Family:D-ribose-5-phosphate isomerase (RpiA), catalytic domain
89 | c3ca8B_ |
| not modelled | 72.9 | 19 | PDB header:structural genomics, unknown function Chain: B: PDB Molecule:protein ydcf; PDBTitle: crystal structure of escherichia coli ydcf, an s-adenosyl-l-methionine2 utilizing enzyme
90 | d1npya1 |
| not modelled | 66.5 | 16 | Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Aminoacid dehydrogenase-like, C-terminal domain
91 | c2pjmA_ |
| not modelled | 63.7 | 19 | PDB header:isomerase Chain: A: PDB Molecule:ribose-5-phosphate isomerase a; PDBTitle: structure of ribose 5-phosphate isomerase a from2 methanocaldococcus jannaschii
92 | c2eggA_ |
| not modelled | 60.4 | 15 | PDB header:oxidoreductase Chain: A: PDB Molecule:shikimate 5-dehydrogenase; PDBTitle: crystal structure of shikimate 5-dehydrogenase (aroe) from2 geobacillus kaustophilus
93 | c3fbtB_ |
| not modelled | 60.3 | 29 | PDB header:oxidoreductase, lyase Chain: B: PDB Molecule:chorismate mutase and shikimate 5-dehydrogenase PDBTitle: crystal structure of a chorismate mutase/shikimate 5-2 dehydrogenase fusion protein from clostridium3 acetobutylicum
94 | d3beda1 |
| not modelled | 59.3 | 10 | Fold:PTS system fructose IIA component-like Superfamily:PTS system fructose IIA component-like Family:EIIA-man component-like
95 | c3tozA_ |
| not modelled | 56.1 | 17 | PDB header:oxidoreductase Chain: A: PDB Molecule:shikimate dehydrogenase; PDBTitle: 2.2 angstrom crystal structure of shikimate 5-dehydrogenase from2 listeria monocytogenes in complex with nad.
96 | d1p77a1 |
| not modelled | 55.5 | 17 | Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Aminoacid dehydrogenase-like, C-terminal domain
97 | c3k13A_ |
| not modelled | 52.8 | 21 | PDB header:transferase Chain: A: PDB Molecule:5-methyltetrahydrofolate-homocysteine methyltransferase; PDBTitle: structure of the pterin-binding domain metr of 5-2 methyltetrahydrofolate-homocysteine methyltransferase from3 bacteroides thetaiotaomicron
98 | d2e7ya1 |
| not modelled | 51.6 | 18 | Fold:Metallo-hydrolase/oxidoreductase Superfamily:Metallo-hydrolase/oxidoreductase Family:RNase Z-like
99 | d2fwra2 |
| not modelled | 49.6 | 12 | Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Tandem AAA-ATPase domain
100 | c1npyA_ |
| not modelled | 49.2 | 16 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical shikimate 5-dehydrogenase-like PDBTitle: structure of shikimate 5-dehydrogenase-like protein hi0607
101 | d1qh5a_ |
| not modelled | 47.6 | 25 | Fold:Metallo-hydrolase/oxidoreductase Superfamily:Metallo-hydrolase/oxidoreductase Family:Glyoxalase II (hydroxyacylglutathione hydrolase)
102 | c1lkzB_ |
| not modelled | 46.6 | 21 | PDB header:isomerase Chain: B: PDB Molecule:ribose 5-phosphate isomerase a; PDBTitle: crystal structure of d-ribose-5-phosphate isomerase (rpia)2 from escherichia coli.
103 | c1xtzA_ |
| not modelled | 44.3 | 13 | PDB header:isomerase Chain: A: PDB Molecule:ribose-5-phosphate isomerase; PDBTitle: crystal structure of the s. cerevisiae d-ribose-5-phosphate isomerase:2 comparison with the archeal and bacterial enzymes
104 | d1g60a_ |
| not modelled | 43.5 | 22 | Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Type II DNA methylase
105 | c1vi2B_ |
| not modelled | 43.4 | 23 | PDB header:oxidoreductase Chain: B: PDB Molecule:shikimate 5-dehydrogenase 2; PDBTitle: crystal structure of shikimate-5-dehydrogenase with nad
106 | c2ohiB_ |
| not modelled | 42.7 | 11 | PDB header:oxidoreductase Chain: B: PDB Molecule:type a flavoprotein fpra; PDBTitle: crystal structure of coenzyme f420h2 oxidase (fpra), a diiron2 flavoprotein, reduced state
107 | c3kwmC_ |
| not modelled | 40.7 | 22 | PDB header:isomerase Chain: C: PDB Molecule:ribose-5-phosphate isomerase a; PDBTitle: crystal structure of ribose-5-isomerase a
108 | c3hnnD_ |
| not modelled | 40.3 | 17 | PDB header:oxidoreductase Chain: D: PDB Molecule:putative diflavin flavoprotein a 5; PDBTitle: crystal structure of putative diflavin flavoprotein a 5 (fragment 1-2 254) from nostoc sp. pcc 7120, northeast structural genomics3 consortium target nsr435a
109 | c1vliA_ |
| not modelled | 40.3 | 27 | PDB header:biosynthetic protein Chain: A: PDB Molecule:spore coat polysaccharide biosynthesis protein spse; PDBTitle: crystal structure of spore coat polysaccharide biosynthesis protein2 spse (bsu37870) from bacillus subtilis at 2.38 a resolution
110 | c2zifB_ |
| not modelled | 39.7 | 20 | PDB header:transferase Chain: B: PDB Molecule:putative modification methylase; PDBTitle: crystal structure of ttha0409, putative dna modification2 methylase from thermus thermophilus hb8- complexed with s-3 adenosyl-l-methionine
111 | d2q0ia1 |
| not modelled | 39.6 | 12 | Fold:Metallo-hydrolase/oxidoreductase Superfamily:Metallo-hydrolase/oxidoreductase Family:PqsE-like
112 | d1eg2a_ |
| not modelled | 38.5 | 16 | Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Type II DNA methylase
113 | c3tbkA_ |
| not modelled | 37.7 | 14 | PDB header:hydrolase Chain: A: PDB Molecule:rig-i helicase domain; PDBTitle: mouse rig-i atpase domain
114 | c1nw6A_ |
| not modelled | 36.3 | 17 | PDB header:transferase Chain: A: PDB Molecule:modification methylase rsri; PDBTitle: structure of the beta class n6-adenine dna methyltransferase rsri2 bound to sinefungin
115 | c2hk8B_ |
| not modelled | 35.8 | 27 | PDB header:oxidoreductase Chain: B: PDB Molecule:shikimate dehydrogenase; PDBTitle: crystal structure of shikimate dehydrogenase from aquifex2 aeolicus at 2.35 angstrom resolution
116 | d1f8fa1 |
| not modelled | 34.8 | 16 | Fold:GroES-like Superfamily:GroES-like Family:Alcohol dehydrogenase-like, N-terminal domain
117 | c3hzhA_ |
| not modelled | 34.5 | 15 | PDB header:signaling protein Chain: A: PDB Molecule:chemotaxis response regulator (chey-3); PDBTitle: crystal structure of the chex-chey-bef3-mg+2 complex from2 borrelia burgdorferi
118 | c3donA_ |
| not modelled | 34.5 | 25 | PDB header:oxidoreductase Chain: A: PDB Molecule:shikimate dehydrogenase; PDBTitle: crystal structure of shikimate dehydrogenase from staphylococcus2 epidermidis
119 | c2qkxA_ |
| not modelled | 34.4 | 17 | PDB header:transferase Chain: A: PDB Molecule:bifunctional protein glmu; PDBTitle: n-acetyl glucosamine 1-phosphate uridyltransferase from mycobacterium2 tuberculosis complex with n-acetyl glucosamine 1-phosphate
120 | d1e5da2 |
| not modelled | 32.2 | 14 | Fold:Metallo-hydrolase/oxidoreductase Superfamily:Metallo-hydrolase/oxidoreductase Family:ROO N-terminal domain-like

Binding site prediction |

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
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Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0