Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP51020
DateThu Jan 5 12:04:49 GMT 2012
Unique Job ID48390544aa74ead0

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c1nvmG_
Top template information
PDB header:lyase/oxidoreductase
Chain: G: PDB Molecule:4-hydroxy-2-oxovalerate aldolase;
PDBTitle: crystal structure of a bifunctional aldolase-dehydrogenase :2 sequestering a reactive and volatile intermediate
Confidence and coverage
Confidence:100.0% Coverage: 99%
335 residues ( 99% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MNGKKLYISDVTLRDGMHAIRHQYSLENVRQIAKALDDARVDSIEVAHGDGLQGSSFNYG
Secondary structure 
SS confidence 
Disorder  ????
????
Disorder confidence 
 
   .........70.........80.........90.........100.........110.........120
Sequence  FGAHSDLEWIEAAADVVKHAKIATLLLPGIGTIHDLKNAWQAGARVVRVATHCTEADVSA
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........130.........140.........150.........160.........170.........180
Sequence  QHIQYARELGMDTVGFLMMSHMTTPENLAKQAKLMEGYGATCIYVVDSGGAMNMSDIRDR
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........190.........200.........210.........220.........230.........240
Sequence  FRALKAELKPETQTGMHAHHNLSLGVANSIAAVEEGCDRIDASLAGMGAGAGNAPLEVFI
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........250.........260.........270.........280.........290.........300
Sequence  AAADKLGWQHGTDLYALMDAADDLVRPLQDRPVRVDRETLALGYAGVYSSFLRHCETAAA
Secondary structure 
SS confidence 
Disorder 
???
??
??
Disorder confidence 
 
   .........310.........320.........330.......
Sequence  RYGLSAVDILVELGKRRMVGGQEDMIVDVALDLRNNK
Secondary structure 
SS confidence 
Disorder 
??
????????
???
Disorder confidence 
 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1nvm chain G

3D model

Region: 3 - 337
Aligned: 335
Modelled: 335
Confidence: 100.0%
Identity: 82%
PDB header:lyase/oxidoreductase
Chain: G: PDB Molecule:4-hydroxy-2-oxovalerate aldolase;
PDBTitle: crystal structure of a bifunctional aldolase-dehydrogenase :2 sequestering a reactive and volatile intermediate

Phyre2

PDB 3ivu chain B

3D model

Region: 2 - 335
Aligned: 315
Modelled: 334
Confidence: 100.0%
Identity: 20%
PDB header:transferase
Chain: B: PDB Molecule:homocitrate synthase, mitochondrial;
PDBTitle: homocitrate synthase lys4 bound to 2-og

Phyre2

PDB 1rr2 chain A

3D model

Region: 2 - 336
Aligned: 330
Modelled: 335
Confidence: 100.0%
Identity: 18%
PDB header:transferase
Chain: A: PDB Molecule:transcarboxylase 5s subunit;
PDBTitle: propionibacterium shermanii transcarboxylase 5s subunit bound to 2-2 ketobutyric acid

Phyre2

PDB 1nvm chain A domain 2

3D model

Region: 2 - 287
Aligned: 286
Modelled: 286
Confidence: 100.0%
Identity: 83%
Fold: TIM beta/alpha-barrel
Superfamily: Aldolase
Family: HMGL-like

Phyre2

PDB 1sr9 chain A

3D model

Region: 3 - 337
Aligned: 324
Modelled: 335
Confidence: 100.0%
Identity: 14%
PDB header:transferase
Chain: A: PDB Molecule:2-isopropylmalate synthase;
PDBTitle: crystal structure of leua from mycobacterium tuberculosis

Phyre2

PDB 2zyf chain A

3D model

Region: 4 - 305
Aligned: 287
Modelled: 302
Confidence: 100.0%
Identity: 19%
PDB header:transferase
Chain: A: PDB Molecule:homocitrate synthase;
PDBTitle: crystal structure of homocitrate synthase from thermus thermophilus2 complexed with magnesuim ion and alpha-ketoglutarate

Phyre2

PDB 2nx9 chain B

3D model

Region: 4 - 334
Aligned: 326
Modelled: 331
Confidence: 100.0%
Identity: 19%
PDB header:lyase
Chain: B: PDB Molecule:oxaloacetate decarboxylase 2, subunit alpha;
PDBTitle: crystal structure of the carboxyltransferase domain of the2 oxaloacetate decarboxylase na+ pump from vibrio cholerae

Phyre2

PDB 3bg5 chain C

3D model

Region: 2 - 336
Aligned: 328
Modelled: 330
Confidence: 100.0%
Identity: 19%
PDB header:ligase
Chain: C: PDB Molecule:pyruvate carboxylase;
PDBTitle: crystal structure of staphylococcus aureus pyruvate2 carboxylase

Phyre2

PDB 3hpx chain B

3D model

Region: 1 - 309
Aligned: 297
Modelled: 309
Confidence: 100.0%
Identity: 16%
PDB header:transferase
Chain: B: PDB Molecule:2-isopropylmalate synthase;
PDBTitle: crystal structure of mycobacterium tuberculosis leua active site2 domain 1-425 (truncation mutant delta:426-644)

Phyre2

PDB 3bg3 chain B

3D model

Region: 2 - 337
Aligned: 329
Modelled: 331
Confidence: 100.0%
Identity: 16%
PDB header:ligase
Chain: B: PDB Molecule:pyruvate carboxylase, mitochondrial;
PDBTitle: crystal structure of human pyruvate carboxylase (missing2 the biotin carboxylase domain at the n-terminus)

Phyre2

PDB 3ble chain A

3D model

Region: 5 - 305
Aligned: 281
Modelled: 301
Confidence: 100.0%
Identity: 23%
PDB header:transferase
Chain: A: PDB Molecule:citramalate synthase from leptospira interrogans;
PDBTitle: crystal structure of the catalytic domain of licms in2 complexed with malonate

Phyre2

PDB 1rqb chain A domain 2

3D model

Region: 2 - 283
Aligned: 278
Modelled: 282
Confidence: 100.0%
Identity: 20%
Fold: TIM beta/alpha-barrel
Superfamily: Aldolase
Family: HMGL-like

Phyre2

PDB 2ftp chain A

3D model

Region: 2 - 273
Aligned: 261
Modelled: 272
Confidence: 100.0%
Identity: 23%
PDB header:lyase
Chain: A: PDB Molecule:hydroxymethylglutaryl-coa lyase;
PDBTitle: crystal structure of hydroxymethylglutaryl-coa lyase from pseudomonas2 aeruginosa

Phyre2

PDB 3dxi chain B

3D model

Region: 6 - 302
Aligned: 294
Modelled: 297
Confidence: 100.0%
Identity: 19%
PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:putative aldolase;
PDBTitle: crystal structure of the n-terminal domain of a putative2 aldolase (bvu_2661) from bacteroides vulgatus

Phyre2

PDB 1ydo chain C

3D model

Region: 3 - 284
Aligned: 269
Modelled: 282
Confidence: 100.0%
Identity: 22%
PDB header:lyase
Chain: C: PDB Molecule:hmg-coa lyase;
PDBTitle: crystal structure of the bacillis subtilis hmg-coa lyase, northeast2 structural genomics target sr181.

Phyre2

PDB 2cw6 chain B

3D model

Region: 3 - 274
Aligned: 261
Modelled: 272
Confidence: 100.0%
Identity: 22%
PDB header:lyase
Chain: B: PDB Molecule:hydroxymethylglutaryl-coa lyase, mitochondrial;
PDBTitle: crystal structure of human hmg-coa lyase: insights into2 catalysis and the molecular basis for3 hydroxymethylglutaric aciduria

Phyre2

PDB 1ydn chain A

3D model

Region: 3 - 270
Aligned: 257
Modelled: 268
Confidence: 100.0%
Identity: 21%
PDB header:lyase
Chain: A: PDB Molecule:hydroxymethylglutaryl-coa lyase;
PDBTitle: crystal structure of the hmg-coa lyase from brucella melitensis,2 northeast structural genomics target lr35.

Phyre2

PDB 3ewb chain X

3D model

Region: 4 - 266
Aligned: 247
Modelled: 252
Confidence: 100.0%
Identity: 26%
PDB header:transferase
Chain: X: PDB Molecule:2-isopropylmalate synthase;
PDBTitle: crystal structure of n-terminal domain of putative 2-2 isopropylmalate synthase from listeria monocytogenes

Phyre2

PDB 1sr9 chain A domain 2

3D model

Region: 3 - 277
Aligned: 264
Modelled: 275
Confidence: 100.0%
Identity: 16%
Fold: TIM beta/alpha-barrel
Superfamily: Aldolase
Family: HMGL-like

Phyre2

PDB 3eeg chain B

3D model

Region: 3 - 266
Aligned: 248
Modelled: 264
Confidence: 100.0%
Identity: 23%
PDB header:transferase
Chain: B: PDB Molecule:2-isopropylmalate synthase;
PDBTitle: crystal structure of a 2-isopropylmalate synthase from2 cytophaga hutchinsonii

Phyre2
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c1nvmG_
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c3ivuB_
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c1rr2A_
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d1nvma2
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c1sr9A_
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c2zyfA_
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c2nx9B_
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c3bg5C_
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c3hpxB_
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c3bg3B_
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c3bleA_
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d1rqba2
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c2ftpA_
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c3dxiB_
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c1ydoC_
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c2cw6B_
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c1ydnA_
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c3ewbX_
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d1sr9a2
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c3eegB_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c1nvmG_
100.0 82 PDB header:lyase/oxidoreductase
Chain: G: PDB Molecule:4-hydroxy-2-oxovalerate aldolase;
PDBTitle: crystal structure of a bifunctional aldolase-dehydrogenase :2 sequestering a reactive and volatile intermediate
2c3ivuB_
100.0 20 PDB header:transferase
Chain: B: PDB Molecule:homocitrate synthase, mitochondrial;
PDBTitle: homocitrate synthase lys4 bound to 2-og
3c1rr2A_
100.0 18 PDB header:transferase
Chain: A: PDB Molecule:transcarboxylase 5s subunit;
PDBTitle: propionibacterium shermanii transcarboxylase 5s subunit bound to 2-2 ketobutyric acid
4d1nvma2
100.0 83 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:HMGL-like
5c1sr9A_
100.0 14 PDB header:transferase
Chain: A: PDB Molecule:2-isopropylmalate synthase;
PDBTitle: crystal structure of leua from mycobacterium tuberculosis
6c2zyfA_
100.0 19 PDB header:transferase
Chain: A: PDB Molecule:homocitrate synthase;
PDBTitle: crystal structure of homocitrate synthase from thermus thermophilus2 complexed with magnesuim ion and alpha-ketoglutarate
7c2nx9B_
100.0 19 PDB header:lyase
Chain: B: PDB Molecule:oxaloacetate decarboxylase 2, subunit alpha;
PDBTitle: crystal structure of the carboxyltransferase domain of the2 oxaloacetate decarboxylase na+ pump from vibrio cholerae
8c3bg5C_
100.0 19 PDB header:ligase
Chain: C: PDB Molecule:pyruvate carboxylase;
PDBTitle: crystal structure of staphylococcus aureus pyruvate2 carboxylase
9c3hpxB_
100.0 16 PDB header:transferase
Chain: B: PDB Molecule:2-isopropylmalate synthase;
PDBTitle: crystal structure of mycobacterium tuberculosis leua active site2 domain 1-425 (truncation mutant delta:426-644)
10c3bg3B_
100.0 16 PDB header:ligase
Chain: B: PDB Molecule:pyruvate carboxylase, mitochondrial;
PDBTitle: crystal structure of human pyruvate carboxylase (missing2 the biotin carboxylase domain at the n-terminus)
11c3bleA_
100.0 23 PDB header:transferase
Chain: A: PDB Molecule:citramalate synthase from leptospira interrogans;
PDBTitle: crystal structure of the catalytic domain of licms in2 complexed with malonate
12d1rqba2
100.0 20 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:HMGL-like
13c2ftpA_
100.0 23 PDB header:lyase
Chain: A: PDB Molecule:hydroxymethylglutaryl-coa lyase;
PDBTitle: crystal structure of hydroxymethylglutaryl-coa lyase from pseudomonas2 aeruginosa
14c3dxiB_
100.0 19 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:putative aldolase;
PDBTitle: crystal structure of the n-terminal domain of a putative2 aldolase (bvu_2661) from bacteroides vulgatus
15c1ydoC_
100.0 22 PDB header:lyase
Chain: C: PDB Molecule:hmg-coa lyase;
PDBTitle: crystal structure of the bacillis subtilis hmg-coa lyase, northeast2 structural genomics target sr181.
16c2cw6B_
100.0 22 PDB header:lyase
Chain: B: PDB Molecule:hydroxymethylglutaryl-coa lyase, mitochondrial;
PDBTitle: crystal structure of human hmg-coa lyase: insights into2 catalysis and the molecular basis for3 hydroxymethylglutaric aciduria
17c1ydnA_
100.0 21 PDB header:lyase
Chain: A: PDB Molecule:hydroxymethylglutaryl-coa lyase;
PDBTitle: crystal structure of the hmg-coa lyase from brucella melitensis,2 northeast structural genomics target lr35.
18c3ewbX_
100.0 26 PDB header:transferase
Chain: X: PDB Molecule:2-isopropylmalate synthase;
PDBTitle: crystal structure of n-terminal domain of putative 2-2 isopropylmalate synthase from listeria monocytogenes
19d1sr9a2
100.0 16 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:HMGL-like
20c3eegB_
100.0 23 PDB header:transferase
Chain: B: PDB Molecule:2-isopropylmalate synthase;
PDBTitle: crystal structure of a 2-isopropylmalate synthase from2 cytophaga hutchinsonii
21c2qf7A_
not modelled 100.0 18 PDB header:ligase
Chain: A: PDB Molecule:pyruvate carboxylase protein;
PDBTitle: crystal structure of a complete multifunctional pyruvate carboxylase2 from rhizobium etli
22d1nvma1
not modelled 98.9 76 Fold:RuvA C-terminal domain-like
Superfamily:post-HMGL domain-like
Family:DmpG/LeuA communication domain-like
23d1xcfa_
not modelled 98.7 16 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
24c2ekcA_
not modelled 98.5 12 PDB header:lyase
Chain: A: PDB Molecule:tryptophan synthase alpha chain;
PDBTitle: structural study of project id aq_1548 from aquifex aeolicus vf5
25c3thaB_
not modelled 98.4 13 PDB header:lyase
Chain: B: PDB Molecule:tryptophan synthase alpha chain;
PDBTitle: tryptophan synthase subunit alpha from campylobacter jejuni.
26c3t7vA_
not modelled 98.4 13 PDB header:transferase
Chain: A: PDB Molecule:methylornithine synthase pylb;
PDBTitle: crystal structure of methylornithine synthase (pylb)
27c3cixA_
not modelled 98.3 14 PDB header:adomet binding protein
Chain: A: PDB Molecule:fefe-hydrogenase maturase;
PDBTitle: x-ray structure of the [fefe]-hydrogenase maturase hyde from2 thermotoga maritima in complex with thiocyanate
28c1r30A_
not modelled 98.3 11 PDB header:transferase
Chain: A: PDB Molecule:biotin synthase;
PDBTitle: the crystal structure of biotin synthase, an s-2 adenosylmethionine-dependent radical enzyme
29d1r30a_
not modelled 98.3 11 Fold:TIM beta/alpha-barrel
Superfamily:Radical SAM enzymes
Family:Biotin synthase
30d1rd5a_
not modelled 98.3 13 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
31d1qopa_
not modelled 98.2 19 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
32c3navB_
not modelled 98.2 14 PDB header:lyase
Chain: B: PDB Molecule:tryptophan synthase alpha chain;
PDBTitle: crystal structure of an alpha subunit of tryptophan synthase from2 vibrio cholerae o1 biovar el tor str. n16961
33d2zdra2
not modelled 98.0 15 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:NeuB-like
34c3f4wA_
not modelled 97.9 18 PDB header:synthase, lyase
Chain: A: PDB Molecule:putative hexulose 6 phosphate synthase;
PDBTitle: the 1.65a crystal structure of 3-hexulose-6-phosphate2 synthase from salmonella typhimurium
35d1geqa_
not modelled 97.9 15 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
36c3ajxA_
not modelled 97.9 17 PDB header:lyase
Chain: A: PDB Molecule:3-hexulose-6-phosphate synthase;
PDBTitle: crystal structure of 3-hexulose-6-phosphate synthase
37d1wbha1
not modelled 97.8 17 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
38c1xuzA_
not modelled 97.7 14 PDB header:biosynthetic protein
Chain: A: PDB Molecule:polysialic acid capsule biosynthesis protein siac;
PDBTitle: crystal structure analysis of sialic acid synthase (neub)from2 neisseria meningitidis, bound to mn2+, phosphoenolpyruvate, and n-3 acetyl mannosaminitol
39d1ad1a_
not modelled 97.7 17 Fold:TIM beta/alpha-barrel
Superfamily:Dihydropteroate synthetase-like
Family:Dihydropteroate synthetase
40c3qc3B_
not modelled 97.7 16 PDB header:isomerase
Chain: B: PDB Molecule:d-ribulose-5-phosphate-3-epimerase;
PDBTitle: crystal structure of a d-ribulose-5-phosphate-3-epimerase (np_954699)2 from homo sapiens at 2.20 a resolution
41d1vlia2
not modelled 97.7 15 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:NeuB-like
42c3jr2D_
not modelled 97.6 17 PDB header:biosynthetic protein
Chain: D: PDB Molecule:hexulose-6-phosphate synthase sgbh;
PDBTitle: x-ray crystal structure of the mg-bound 3-keto-l-gulonate-6-phosphate2 decarboxylase from vibrio cholerae o1 biovar el tor str. n16961
43c1vliA_
not modelled 97.6 15 PDB header:biosynthetic protein
Chain: A: PDB Molecule:spore coat polysaccharide biosynthesis protein spse;
PDBTitle: crystal structure of spore coat polysaccharide biosynthesis protein2 spse (bsu37870) from bacillus subtilis at 2.38 a resolution
44d1q6oa_
not modelled 97.6 12 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Decarboxylase
45d1tqxa_
not modelled 97.5 8 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:D-ribulose-5-phosphate 3-epimerase
46d1rvga_
not modelled 97.5 20 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class II FBP aldolase
47c1tx2A_
not modelled 97.5 15 PDB header:transferase
Chain: A: PDB Molecule:dhps, dihydropteroate synthase;
PDBTitle: dihydropteroate synthetase, with bound inhibitor manic, from bacillus2 anthracis
48d1tx2a_
not modelled 97.5 15 Fold:TIM beta/alpha-barrel
Superfamily:Dihydropteroate synthetase-like
Family:Dihydropteroate synthetase
49c3c52B_
not modelled 97.5 14 PDB header:lyase
Chain: B: PDB Molecule:fructose-bisphosphate aldolase;
PDBTitle: class ii fructose-1,6-bisphosphate aldolase from2 helicobacter pylori in complex with3 phosphoglycolohydroxamic acid, a competitive inhibitor
50d1ujpa_
not modelled 97.5 21 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
51d1mxsa_
not modelled 97.5 14 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
52c3exsB_
not modelled 97.4 14 PDB header:lyase
Chain: B: PDB Molecule:rmpd (hexulose-6-phosphate synthase);
PDBTitle: crystal structure of kgpdc from streptococcus mutans in2 complex with d-r5p
53d1h1ya_
not modelled 97.4 19 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:D-ribulose-5-phosphate 3-epimerase
54d1tqja_
not modelled 97.2 15 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:D-ribulose-5-phosphate 3-epimerase
55d1vhca_
not modelled 97.2 13 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
56d1wa3a1
not modelled 97.2 18 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
57d1d9ea_
not modelled 97.2 10 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I DAHP synthetase
58c3nvtA_
not modelled 97.1 16 PDB header:transferase/isomerase
Chain: A: PDB Molecule:3-deoxy-d-arabino-heptulosonate 7-phosphate synthase;
PDBTitle: 1.95 angstrom crystal structure of a bifunctional 3-deoxy-7-2 phosphoheptulonate synthase/chorismate mutase (aroa) from listeria3 monocytogenes egd-e
59d1rpxa_
not modelled 97.0 14 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:D-ribulose-5-phosphate 3-epimerase
60c3js3C_
not modelled 97.0 15 PDB header:lyase
Chain: C: PDB Molecule:3-dehydroquinate dehydratase;
PDBTitle: crystal structure of type i 3-dehydroquinate dehydratase (arod) from2 clostridium difficile with covalent reaction intermediate
61d1ka9f_
not modelled 97.0 15 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Histidine biosynthesis enzymes
62d1thfd_
not modelled 96.9 13 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Histidine biosynthesis enzymes
63c2c3zA_
not modelled 96.9 11 PDB header:lyase
Chain: A: PDB Molecule:indole-3-glycerol phosphate synthase;
PDBTitle: crystal structure of a truncated variant of indole-3-2 glycerol phosphate synthase from sulfolobus solfataricus
64c3igsB_
not modelled 96.9 16 PDB header:isomerase
Chain: B: PDB Molecule:n-acetylmannosamine-6-phosphate 2-epimerase 2;
PDBTitle: structure of the salmonella enterica n-acetylmannosamine-6-phosphate2 2-epimerase
65d1ajza_
not modelled 96.8 18 Fold:TIM beta/alpha-barrel
Superfamily:Dihydropteroate synthetase-like
Family:Dihydropteroate synthetase
66c3g8rA_
not modelled 96.8 12 PDB header:biosynthetic protein
Chain: A: PDB Molecule:probable spore coat polysaccharide biosynthesis protein e;
PDBTitle: crystal structure of putative spore coat polysaccharide biosynthesis2 protein e from chromobacterium violaceum atcc 12472
67c2bdqA_
not modelled 96.7 15 PDB header:metal transport
Chain: A: PDB Molecule:copper homeostasis protein cutc;
PDBTitle: crystal structure of the putative copper homeostasis2 protein cutc from streptococcus agalactiae, northeast3 strucural genomics target sar15.
68c2v82A_
not modelled 96.7 16 PDB header:lyase
Chain: A: PDB Molecule:2-dehydro-3-deoxy-6-phosphogalactonate aldolase;
PDBTitle: kdpgal complexed to kdpgal
69d1j5ta_
not modelled 96.6 13 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
70c3tr9A_
not modelled 96.6 16 PDB header:transferase
Chain: A: PDB Molecule:dihydropteroate synthase;
PDBTitle: structure of a dihydropteroate synthase (folp) in complex with pteroic2 acid from coxiella burnetii
71d1piia2
not modelled 96.6 12 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
72c3stgA_
not modelled 96.5 10 PDB header:transferase
Chain: A: PDB Molecule:2-dehydro-3-deoxyphosphooctonate aldolase;
PDBTitle: crystal structure of a58p, del(n59), and loop 7 truncated mutant of 3-2 deoxy-d-manno-octulosonate 8-phosphate synthase (kdo8ps) from3 neisseria meningitidis
73c3pg8B_
not modelled 96.5 16 PDB header:transferase
Chain: B: PDB Molecule:phospho-2-dehydro-3-deoxyheptonate aldolase;
PDBTitle: truncated form of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase2 from thermotoga maritima
74c3sz8D_
not modelled 96.5 13 PDB header:transferase
Chain: D: PDB Molecule:2-dehydro-3-deoxyphosphooctonate aldolase 2;
PDBTitle: crystal structure of 2-dehydro-3-deoxyphosphooctonate aldolase from2 burkholderia pseudomallei
75d2flia1
not modelled 96.5 11 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:D-ribulose-5-phosphate 3-epimerase
76d1vc4a_
not modelled 96.4 14 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
77c3q58A_
not modelled 96.3 16 PDB header:isomerase
Chain: A: PDB Molecule:n-acetylmannosamine-6-phosphate 2-epimerase;
PDBTitle: structure of n-acetylmannosamine-6-phosphate epimerase from salmonella2 enterica
78c3inpA_
not modelled 96.3 13 PDB header:isomerase
Chain: A: PDB Molecule:d-ribulose-phosphate 3-epimerase;
PDBTitle: 2.05 angstrom resolution crystal structure of d-ribulose-phosphate 3-2 epimerase from francisella tularensis.
79c2h9aB_
not modelled 96.2 12 PDB header:oxidoreductase
Chain: B: PDB Molecule:co dehydrogenase/acetyl-coa synthase, iron-
PDBTitle: corrinoid iron-sulfur protein
80c2vp8A_
not modelled 96.2 16 PDB header:transferase
Chain: A: PDB Molecule:dihydropteroate synthase 2;
PDBTitle: structure of mycobacterium tuberculosis rv1207
81d1h5ya_
not modelled 96.1 17 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Histidine biosynthesis enzymes
82d1gqna_
not modelled 96.1 14 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
83d1olta_
not modelled 96.1 17 Fold:TIM beta/alpha-barrel
Superfamily:Radical SAM enzymes
Family:Oxygen-independent coproporphyrinogen III oxidase HemN
84d1gvfa_
not modelled 96.1 13 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class II FBP aldolase
85c2iswB_
not modelled 96.0 20 PDB header:lyase
Chain: B: PDB Molecule:putative fructose-1,6-bisphosphate aldolase;
PDBTitle: structure of giardia fructose-1,6-biphosphate aldolase in2 complex with phosphoglycolohydroxamate
86c1zcoA_
not modelled 95.9 10 PDB header:lyase
Chain: A: PDB Molecule:2-dehydro-3-deoxyphosphoheptonate aldolase;
PDBTitle: crystal structure of pyrococcus furiosus 3-deoxy-d-arabino-2 heptulosonate 7-phosphate synthase
87c3chvA_
not modelled 95.9 11 PDB header:metal binding protein
Chain: A: PDB Molecule:prokaryotic domain of unknown function (duf849) with a tim
PDBTitle: crystal structure of a prokaryotic domain of unknown function (duf849)2 member (spoa0042) from silicibacter pomeroyi dss-3 at 1.45 a3 resolution
88d1i4na_
not modelled 95.9 14 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
89c2yciX_
not modelled 95.9 11 PDB header:transferase
Chain: X: PDB Molecule:5-methyltetrahydrofolate corrinoid/iron sulfur protein
PDBTitle: methyltransferase native
90c2yr1B_
not modelled 95.8 15 PDB header:lyase
Chain: B: PDB Molecule:3-dehydroquinate dehydratase;
PDBTitle: crystal structure of 3-dehydroquinate dehydratase from geobacillus2 kaustophilus hta426
91d1n7ka_
not modelled 95.8 15 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
92c3e96B_
not modelled 95.8 11 PDB header:lyase
Chain: B: PDB Molecule:dihydrodipicolinate synthase;
PDBTitle: crystal structure of dihydrodipicolinate synthase from2 bacillus clausii
93c3pm6B_
not modelled 95.7 16 PDB header:lyase
Chain: B: PDB Molecule:putative fructose-bisphosphate aldolase;
PDBTitle: crystal structure of a putative fructose-1,6-biphosphate aldolase from2 coccidioides immitis solved by combined sad mr
94c3l2iB_
not modelled 95.7 18 PDB header:lyase
Chain: B: PDB Molecule:3-dehydroquinate dehydratase;
PDBTitle: 1.85 angstrom crystal structure of the 3-dehydroquinate dehydratase2 (arod) from salmonella typhimurium lt2.
95c3ngjC_
not modelled 95.6 16 PDB header:lyase
Chain: C: PDB Molecule:deoxyribose-phosphate aldolase;
PDBTitle: crystal structure of a putative deoxyribose-phosphate aldolase from2 entamoeba histolytica
96d1vr6a1
not modelled 95.6 14 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I DAHP synthetase
97c3q94B_
not modelled 95.5 15 PDB header:lyase
Chain: B: PDB Molecule:fructose-bisphosphate aldolase, class ii;
PDBTitle: the crystal structure of fructose 1,6-bisphosphate aldolase from2 bacillus anthracis str. 'ames ancestor'
98c3qxbB_
not modelled 95.5 11 PDB header:isomerase
Chain: B: PDB Molecule:putative xylose isomerase;
PDBTitle: crystal structure of a putative xylose isomerase (yp_426450.1) from2 rhodospirillum rubrum atcc 11170 at 1.90 a resolution
99c2yw3E_
not modelled 95.4 14 PDB header:lyase
Chain: E: PDB Molecule:4-hydroxy-2-oxoglutarate aldolase/2-deydro-3-
PDBTitle: crystal structure analysis of the 4-hydroxy-2-oxoglutarate aldolase/2-2 deydro-3-deoxyphosphogluconate aldolase from tthb1
100d1djqa1
not modelled 95.4 14 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
101c3d0cB_
not modelled 95.4 10 PDB header:lyase
Chain: B: PDB Molecule:dihydrodipicolinate synthase;
PDBTitle: crystal structure of dihydrodipicolinate synthase from2 oceanobacillus iheyensis at 1.9 a resolution
102c3dz1A_
not modelled 95.4 13 PDB header:lyase
Chain: A: PDB Molecule:dihydrodipicolinate synthase;
PDBTitle: crystal structure of dihydrodipicolinate synthase from2 rhodopseudomonas palustris at 1.87a resolution
103c1telA_
not modelled 95.4 13 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:ribulose bisphosphate carboxylase, large subunit;
PDBTitle: crystal structure of a rubisco-like protein from chlorobium2 tepidum
104c2pgeA_
not modelled 95.4 18 PDB header:lyase
Chain: A: PDB Molecule:menc;
PDBTitle: crystal structure of menc from desulfotalea psychrophila2 lsv54
105c3elfA_
not modelled 95.3 14 PDB header:lyase
Chain: A: PDB Molecule:fructose-bisphosphate aldolase;
PDBTitle: structural characterization of tetrameric mycobacterium tuberculosis2 fructose 1,6-bisphosphate aldolase - substrate binding and catalysis3 mechanism of a class iia bacterial aldolase
106c3ct7E_
not modelled 95.3 14 PDB header:isomerase
Chain: E: PDB Molecule:d-allulose-6-phosphate 3-epimerase;
PDBTitle: crystal structure of d-allulose 6-phosphate 3-epimerase2 from escherichia coli k-12
107c3qjaA_
not modelled 95.3 19 PDB header:lyase
Chain: A: PDB Molecule:indole-3-glycerol phosphate synthase;
PDBTitle: crystal structure of the mycobacterium tuberculosis indole-3-glycerol2 phosphate synthase (trpc) in apo form
108d1yxya1
not modelled 95.3 14 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:NanE-like
109c2qiwA_
not modelled 95.2 17 PDB header:transferase
Chain: A: PDB Molecule:pep phosphonomutase;
PDBTitle: crystal structure of a putative phosphoenolpyruvate phosphonomutase2 (ncgl1015, cgl1060) from corynebacterium glutamicum atcc 13032 at3 1.80 a resolution
110d1ub3a_
not modelled 95.2 16 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
111c3k13A_
not modelled 95.1 16 PDB header:transferase
Chain: A: PDB Molecule:5-methyltetrahydrofolate-homocysteine methyltransferase;
PDBTitle: structure of the pterin-binding domain metr of 5-2 methyltetrahydrofolate-homocysteine methyltransferase from3 bacteroides thetaiotaomicron
112d2q02a1
not modelled 95.0 8 Fold:TIM beta/alpha-barrel
Superfamily:Xylose isomerase-like
Family:IolI-like
113d1k77a_
not modelled 95.0 15 Fold:TIM beta/alpha-barrel
Superfamily:Xylose isomerase-like
Family:Hypothetical protein YgbM (EC1530)
114c3nwrA_
not modelled 94.9 18 PDB header:lyase
Chain: A: PDB Molecule:a rubisco-like protein;
PDBTitle: crystal structure of a rubisco-like protein from burkholderia fungorum
115d1a53a_
not modelled 94.8 13 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
116d1o60a_
not modelled 94.8 11 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I DAHP synthetase
117d1o0ya_
not modelled 94.7 14 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
118c2r8wB_
not modelled 94.7 13 PDB header:lyase
Chain: B: PDB Molecule:agr_c_1641p;
PDBTitle: the crystal structure of dihydrodipicolinate synthase (atu0899) from2 agrobacterium tumefaciens str. c58
119d1tv8a_
not modelled 94.5 15 Fold:TIM beta/alpha-barrel
Superfamily:Radical SAM enzymes
Family:MoCo biosynthesis proteins
120d1xxxa1
not modelled 94.4 14 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0