Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	L	Q	Q	V	P	T	R	A	F	H	V	M	A	K	P	S	G	S	D	C	N	L	N	C	D	Y	C	F	Y	L	E	K	Q	S	L	Y	R	E	K	P	V	T	H	M	D	D	D	T	L	E	A	Y	V	R	H	Y	I	A	A
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?																									?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		S	E	P	Q	N	E	V	A	F	T	W	Q	G	G	E	P	T	L	L	G	L	A	F	Y	R	R	A	V	A	L	Q	A	K	Y	G	A	G	R	K	I	S	N	S	F	Q	T	N	G	V	L	L	D	D	E	W	C	A	F	L	A
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		E	H	H	F	L	V	G	L	S	L	D	G	P	P	E	I	H	N	Q	Y	R	V	T	K	G	G	R	P	T	H	K	L	V	M	R	A	L	T	L	L	Q	K	H	H	V	D	Y	N	V	L	V	C	V	N	R	T	S	A	Q	Q
Secondary structure
SS confidence
Disorder																									?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		P	L	Q	V	Y	D	F	L	C	D	A	G	V	E	F	I	Q	F	I	P	V	V	E	R	L	A	D	E	T	T	A	R	D	G	L	K	L	H	A	P	G	D	I	Q	G	E	L	T	E	W	S	V	R	P	E	E	F	G	E	F
Secondary structure
SS confidence
Disorder																										?	?	?	?	?		?											?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		L	V	A	I	F	D	H	W	I	K	R	D	V	G	K	I	F	V	M	N	I	E	W	A	F	A	N	F	V	G	A	P	G	A	V	C	H	H	Q	P	T	C	G	R	S	V	I	V	E	H	N	G	D	V	Y	A	C	D	H	Y
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		V	Y	P	Q	Y	R	L	G	N	M	H	Q	Q	T	I	A	E	M	I	D	S	P	Q	Q	Q	A	F	G	E	D	K	F	K	Q	L	P	A	Q	C	R	S	C	N	V	L	K	A	C	W	G	G	C	P	K	H	R	F	M	L	D
Secondary structure
SS confidence
Disorder																															?	?		?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.
Sequence		A	S	G	K	P	G	L	N	Y	L	C	A	G	Y	Q	R	Y	F	R	H	L	P	P	Y	L	K	A	M	A	D	L	L	A	H	G	R	P	A	S	D	I	M	H	A	H	L	L	V	V	S	K
Secondary structure
SS confidence
Disorder			?	?																															?		?											?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1tv8 chain A Region: 2 - 338 Aligned: 308 Modelled: 321 Confidence: 100.0% Identity: 17% Fold: TIM beta/alpha-barrel Superfamily: Radical SAM enzymes Family: MoCo biosynthesis proteins Phyre2 PDB 2yx0 chain A Region: 11 - 209 Aligned: 193 Modelled: 199 Confidence: 99.9% Identity: 17% PDB header:metal binding protein Chain: A: PDB Molecule:radical sam enzyme; PDBTitle: crystal structure of p. horikoshii tyw1 Phyre2 PDB 3c8f chain A Region: 2 - 205 Aligned: 187 Modelled: 203 Confidence: 99.8% Identity: 21% PDB header:oxidoreductase Chain: A: PDB Molecule:pyruvate formate-lyase 1-activating enzyme; PDBTitle: 4fe-4s-pyruvate formate-lyase activating enzyme with2 partially disordered adomet Phyre2 PDB 1olt chain A Region: 2 - 261 Aligned: 242 Modelled: 258 Confidence: 99.7% Identity: 12% Fold: TIM beta/alpha-barrel Superfamily: Radical SAM enzymes Family: Oxygen-independent coproporphyrinogen III oxidase HemN Phyre2 PDB 2a5h chain C Region: 9 - 208 Aligned: 177 Modelled: 187 Confidence: 99.6% Identity: 15% PDB header:isomerase Chain: C: PDB Molecule:l-lysine 2,3-aminomutase; PDBTitle: 2.1 angstrom x-ray crystal structure of lysine-2,3-aminomutase from2 clostridium subterminale sb4, with michaelis analog (l-alpha-lysine3 external aldimine form of pyridoxal-5'-phosphate). Phyre2 PDB 2z2u chain A Region: 20 - 208 Aligned: 173 Modelled: 189 Confidence: 99.6% Identity: 17% PDB header:metal binding protein Chain: A: PDB Molecule:upf0026 protein mj0257; PDBTitle: crystal structure of archaeal tyw1 Phyre2 PDB 3can chain A Region: 69 - 205 Aligned: 127 Modelled: 136 Confidence: 99.5% Identity: 17% PDB header:lyase activator Chain: A: PDB Molecule:pyruvate-formate lyase-activating enzyme; PDBTitle: crystal structure of a domain of pyruvate-formate lyase-activating2 enzyme from bacteroides vulgatus atcc 8482 Phyre2 PDB 3t7v chain A Region: 10 - 204 Aligned: 181 Modelled: 191 Confidence: 99.5% Identity: 8% PDB header:transferase Chain: A: PDB Molecule:methylornithine synthase pylb; PDBTitle: crystal structure of methylornithine synthase (pylb) Phyre2 PDB 3cix chain A Region: 10 - 203 Aligned: 177 Modelled: 190 Confidence: 99.4% Identity: 13% PDB header:adomet binding protein Chain: A: PDB Molecule:fefe-hydrogenase maturase; PDBTitle: x-ray structure of the [fefe]-hydrogenase maturase hyde from2 thermotoga maritima in complex with thiocyanate Phyre2 PDB 3rfa chain A Region: 6 - 204 Aligned: 188 Modelled: 199 Confidence: 99.4% Identity: 15% PDB header:oxidoreductase Chain: A: PDB Molecule:ribosomal rna large subunit methyltransferase n; PDBTitle: x-ray structure of rlmn from escherichia coli in complex with s-2 adenosylmethionine Phyre2 PDB 1r30 chain A Region: 10 - 204 Aligned: 182 Modelled: 191 Confidence: 99.4% Identity: 13% Fold: TIM beta/alpha-barrel Superfamily: Radical SAM enzymes Family: Biotin synthase Phyre2 PDB 1r30 chain A Region: 10 - 204 Aligned: 182 Modelled: 191 Confidence: 99.4% Identity: 13% PDB header:transferase Chain: A: PDB Molecule:biotin synthase; PDBTitle: the crystal structure of biotin synthase, an s-2 adenosylmethionine-dependent radical enzyme Phyre2 PDB 2qgq chain F Region: 25 - 203 Aligned: 169 Modelled: 170 Confidence: 98.6% Identity: 8% PDB header:structural genomics, unknown function Chain: F: PDB Molecule:protein tm_1862; PDBTitle: crystal structure of tm_1862 from thermotoga maritima.2 northeast structural genomics consortium target vr77 Phyre2 PDB 3ivu chain B Region: 38 - 198 Aligned: 146 Modelled: 157 Confidence: 94.5% Identity: 10% PDB header:transferase Chain: B: PDB Molecule:homocitrate synthase, mitochondrial; PDBTitle: homocitrate synthase lys4 bound to 2-og Phyre2 PDB 3ble chain A Region: 38 - 198 Aligned: 154 Modelled: 161 Confidence: 94.5% Identity: 12% PDB header:transferase Chain: A: PDB Molecule:citramalate synthase from leptospira interrogans; PDBTitle: crystal structure of the catalytic domain of licms in2 complexed with malonate Phyre2 PDB 3ewb chain X Region: 45 - 198 Aligned: 145 Modelled: 150 Confidence: 93.2% Identity: 11% PDB header:transferase Chain: X: PDB Molecule:2-isopropylmalate synthase; PDBTitle: crystal structure of n-terminal domain of putative 2-2 isopropylmalate synthase from listeria monocytogenes Phyre2 PDB 2ftp chain A Region: 41 - 198 Aligned: 149 Modelled: 154 Confidence: 91.4% Identity: 10% PDB header:lyase Chain: A: PDB Molecule:hydroxymethylglutaryl-coa lyase; PDBTitle: crystal structure of hydroxymethylglutaryl-coa lyase from pseudomonas2 aeruginosa Phyre2 PDB 2cw6 chain B Region: 41 - 198 Aligned: 149 Modelled: 158 Confidence: 86.2% Identity: 8% PDB header:lyase Chain: B: PDB Molecule:hydroxymethylglutaryl-coa lyase, mitochondrial; PDBTitle: crystal structure of human hmg-coa lyase: insights into2 catalysis and the molecular basis for3 hydroxymethylglutaric aciduria Phyre2 PDB 1ydo chain C Region: 38 - 198 Aligned: 152 Modelled: 155 Confidence: 76.3% Identity: 11% PDB header:lyase Chain: C: PDB Molecule:hmg-coa lyase; PDBTitle: crystal structure of the bacillis subtilis hmg-coa lyase, northeast2 structural genomics target sr181. Phyre2 PDB 3eeg chain B Region: 45 - 198 Aligned: 145 Modelled: 150 Confidence: 76.2% Identity: 8% PDB header:transferase Chain: B: PDB Molecule:2-isopropylmalate synthase; PDBTitle: crystal structure of a 2-isopropylmalate synthase from2 cytophaga hutchinsonii Phyre2 1 d1tv8a_ 2 c2yx0A_ 3 c3c8fA_ 4 d1olta_ 5 c2a5hC_ 6 c2z2uA_ 7 c3canA_ 8 c3t7vA_ 9 c3cixA_ 10 c3rfaA_ 11 d1r30a_ 12 c1r30A_ 13 c2qgqF_ 14 c3ivuB_ 15 c3bleA_ 16 c3ewbX_ 17 c2ftpA_ 18 c2cw6B_ 19 c1ydoC_ 20 c3eegB_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1tv8a_ 100.0 17 Fold:TIM beta/alpha-barrel Superfamily:Radical SAM enzymes Family:MoCo biosynthesis proteins 2 c2yx0A_ 99.9 17 PDB header:metal binding protein Chain: A: PDB Molecule:radical sam enzyme; PDBTitle: crystal structure of p. horikoshii tyw1 3 c3c8fA_ 99.8 21 PDB header:oxidoreductase Chain: A: PDB Molecule:pyruvate formate-lyase 1-activating enzyme; PDBTitle: 4fe-4s-pyruvate formate-lyase activating enzyme with2 partially disordered adomet 4 d1olta_ 99.7 12 Fold:TIM beta/alpha-barrel Superfamily:Radical SAM enzymes Family:Oxygen-independent coproporphyrinogen III oxidase HemN 5 c2a5hC_ 99.6 15 PDB header:isomerase Chain: C: PDB Molecule:l-lysine 2,3-aminomutase; PDBTitle: 2.1 angstrom x-ray crystal structure of lysine-2,3-aminomutase from2 clostridium subterminale sb4, with michaelis analog (l-alpha-lysine3 external aldimine form of pyridoxal-5'-phosphate). 6 c2z2uA_ 99.6 17 PDB header:metal binding protein Chain: A: PDB Molecule:upf0026 protein mj0257; PDBTitle: crystal structure of archaeal tyw1 7 c3canA_ 99.5 17 PDB header:lyase activator Chain: A: PDB Molecule:pyruvate-formate lyase-activating enzyme; PDBTitle: crystal structure of a domain of pyruvate-formate lyase-activating2 enzyme from bacteroides vulgatus atcc 8482 8 c3t7vA_ 99.5 8 PDB header:transferase Chain: A: PDB Molecule:methylornithine synthase pylb; PDBTitle: crystal structure of methylornithine synthase (pylb) 9 c3cixA_ 99.4 13 PDB header:adomet binding protein Chain: A: PDB Molecule:fefe-hydrogenase maturase; PDBTitle: x-ray structure of the [fefe]-hydrogenase maturase hyde from2 thermotoga maritima in complex with thiocyanate 10 c3rfaA_ 99.4 15 PDB header:oxidoreductase Chain: A: PDB Molecule:ribosomal rna large subunit methyltransferase n; PDBTitle: x-ray structure of rlmn from escherichia coli in complex with s-2 adenosylmethionine 11 d1r30a_ 99.4 13 Fold:TIM beta/alpha-barrel Superfamily:Radical SAM enzymes Family:Biotin synthase 12 c1r30A_ 99.4 13 PDB header:transferase Chain: A: PDB Molecule:biotin synthase; PDBTitle: the crystal structure of biotin synthase, an s-2 adenosylmethionine-dependent radical enzyme 13 c2qgqF_ 98.6 8 PDB header:structural genomics, unknown function Chain: F: PDB Molecule:protein tm_1862; PDBTitle: crystal structure of tm_1862 from thermotoga maritima.2 northeast structural genomics consortium target vr77 14 c3ivuB_ 94.5 10 PDB header:transferase Chain: B: PDB Molecule:homocitrate synthase, mitochondrial; PDBTitle: homocitrate synthase lys4 bound to 2-og 15 c3bleA_ 94.5 12 PDB header:transferase Chain: A: PDB Molecule:citramalate synthase from leptospira interrogans; PDBTitle: crystal structure of the catalytic domain of licms in2 complexed with malonate 16 c3ewbX_ 93.2 11 PDB header:transferase Chain: X: PDB Molecule:2-isopropylmalate synthase; PDBTitle: crystal structure of n-terminal domain of putative 2-2 isopropylmalate synthase from listeria monocytogenes 17 c2ftpA_ 91.4 10 PDB header:lyase Chain: A: PDB Molecule:hydroxymethylglutaryl-coa lyase; PDBTitle: crystal structure of hydroxymethylglutaryl-coa lyase from pseudomonas2 aeruginosa 18 c2cw6B_ 86.2 8 PDB header:lyase Chain: B: PDB Molecule:hydroxymethylglutaryl-coa lyase, mitochondrial; PDBTitle: crystal structure of human hmg-coa lyase: insights into2 catalysis and the molecular basis for3 hydroxymethylglutaric aciduria 19 c1ydoC_ 76.3 11 PDB header:lyase Chain: C: PDB Molecule:hmg-coa lyase; PDBTitle: crystal structure of the bacillis subtilis hmg-coa lyase, northeast2 structural genomics target sr181. 20 c3eegB_ 76.2 8 PDB header:transferase Chain: B: PDB Molecule:2-isopropylmalate synthase; PDBTitle: crystal structure of a 2-isopropylmalate synthase from2 cytophaga hutchinsonii 21 c1ydnA_ not modelled 70.1 10 PDB header:lyase Chain: A: PDB Molecule:hydroxymethylglutaryl-coa lyase; PDBTitle: crystal structure of the hmg-coa lyase from brucella melitensis,2 northeast structural genomics target lr35. 22 c2knpA_ not modelled 49.8 36 PDB header:unknown function Chain: A: PDB Molecule:mcocc-1; PDBTitle: isolation and characterization of peptides from momordica2 cochinchinensis seeds. 23 c2qv5A_ not modelled 48.1 11 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein atu2773; PDBTitle: crystal structure of uncharacterized protein atu2773 from2 agrobacterium tumefaciens c58 24 c2wanA_ not modelled 43.1 17 PDB header:hydrolase Chain: A: PDB Molecule:pullulanase; PDBTitle: pullulanase from bacillus acidopullulyticus 25 d1qwga_ not modelled 39.4 15 Fold:TIM beta/alpha-barrel Superfamily:(2r)-phospho-3-sulfolactate synthase ComA Family:(2r)-phospho-3-sulfolactate synthase ComA 26 c1ehaA_ not modelled 39.1 22 PDB header:hydrolase Chain: A: PDB Molecule:glycosyltrehalose trehalohydrolase; PDBTitle: crystal structure of glycosyltrehalose trehalohydrolase2 from sulfolobus solfataricus 27 d1gjwa2 not modelled 38.9 14 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:Amylase, catalytic domain 28 c1bf2A_ not modelled 38.2 18 PDB header:hydrolase Chain: A: PDB Molecule:isoamylase; PDBTitle: structure of pseudomonas isoamylase 29 c3k1dA_ not modelled 36.3 22 PDB header:transferase Chain: A: PDB Molecule:1,4-alpha-glucan-branching enzyme; PDBTitle: crystal structure of glycogen branching enzyme synonym: 1,4-alpha-d-2 glucan:1,4-alpha-d-glucan 6-glucosyl-transferase from mycobacterium3 tuberculosis h37rv 30 c3m07A_ not modelled 36.1 25 PDB header:unknown function Chain: A: PDB Molecule:putative alpha amylase; PDBTitle: 1.4 angstrom resolution crystal structure of putative alpha2 amylase from salmonella typhimurium. 31 c2by0A_ not modelled 35.6 24 PDB header:hydrolase Chain: A: PDB Molecule:maltooligosyltrehalose trehalohydrolase; PDBTitle: is radiation damage dependent on the dose-rate used during2 macromolecular crystallography data collection 32 d1dd9a_ not modelled 34.6 11 Fold:DNA primase core Superfamily:DNA primase core Family:DNA primase DnaG catalytic core 33 c1dd9A_ not modelled 34.6 11 PDB header:transferase Chain: A: PDB Molecule:dna primase; PDBTitle: structure of the dnag catalytic core 34 c1m7xC_ not modelled 33.8 20 PDB header:transferase Chain: C: PDB Molecule:1,4-alpha-glucan branching enzyme; PDBTitle: the x-ray crystallographic structure of branching enzyme 35 c1nvmG_ not modelled 33.5 10 PDB header:lyase/oxidoreductase Chain: G: PDB Molecule:4-hydroxy-2-oxovalerate aldolase; PDBTitle: crystal structure of a bifunctional aldolase-dehydrogenase :2 sequestering a reactive and volatile intermediate 36 d2nlya1 not modelled 29.9 10 Fold:7-stranded beta/alpha barrel Superfamily:Glycoside hydrolase/deacetylase Family:Divergent polysaccharide deacetylase 37 c2vncB_ not modelled 29.8 17 PDB header:hydrolase Chain: B: PDB Molecule:glycogen operon protein glgx; PDBTitle: crystal structure of glycogen debranching enzyme trex from2 sulfolobus solfataricus 38 c3ol0C_ not modelled 25.4 19 PDB header:de novo protein Chain: C: PDB Molecule:de novo designed monomer trefoil-fold sub-domain which PDBTitle: crystal structure of monofoil-4p homo-trimer: de novo designed monomer2 trefoil-fold sub-domain which forms homo-trimer assembly 39 c1gjuA_ not modelled 23.5 14 PDB header:transferase Chain: A: PDB Molecule:maltodextrin glycosyltransferase; PDBTitle: maltosyltransferase from thermotoga maritima 40 d2d3na2 not modelled 22.6 9 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:Amylase, catalytic domain 41 c2dh3A_ not modelled 22.2 18 PDB header:transport protein, signaling protein Chain: A: PDB Molecule:4f2 cell-surface antigen heavy chain; PDBTitle: crystal structure of human ed-4f2hc 42 c2vefB_ not modelled 22.1 13 PDB header:transferase Chain: B: PDB Molecule:dihydropteroate synthase; PDBTitle: dihydropteroate synthase from streptococcus pneumoniae 43 d1e43a2 not modelled 21.6 14 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:Amylase, catalytic domain 44 d1qt1a_ not modelled 20.3 11 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:Xylose isomerase 45 c2au3A_ not modelled 20.3 21 PDB header:transferase Chain: A: PDB Molecule:dna primase; PDBTitle: crystal structure of the aquifex aeolicus primase (zinc binding and2 rna polymerase domains) 46 d1m7xa3 not modelled 20.1 15 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:Amylase, catalytic domain 47 c1x3lA_ not modelled 19.9 19 PDB header:transferase Chain: A: PDB Molecule:hypothetical protein ph0495; PDBTitle: crystal structure of the ph0495 protein from pyrococccus horikoshii2 ot3 48 d2gjpa2 not modelled 19.8 13 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:Amylase, catalytic domain 49 d1ob0a2 not modelled 19.7 10 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:Amylase, catalytic domain 50 d1uwva2 not modelled 19.6 45 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:(Uracil-5-)-methyltransferase 51 d2aaaa2 not modelled 19.3 15 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:Amylase, catalytic domain 52 c3amlA_ not modelled 19.0 14 PDB header:transferase Chain: A: PDB Molecule:os06g0726400 protein; PDBTitle: structure of the starch branching enzyme i (bei) from oryza sativa l 53 c3dz1A_ not modelled 18.8 14 PDB header:lyase Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from2 rhodopseudomonas palustris at 1.87a resolution 54 d2fcja1 not modelled 18.8 18 Fold:Toprim domain Superfamily:Toprim domain Family:Toprim domain 55 d1ps9a1 not modelled 18.6 14 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 56 d1bf2a3 not modelled 18.5 18 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:Amylase, catalytic domain 57 d1z6ma1 not modelled 18.4 19 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:DsbA-like 58 d1v93a_ not modelled 18.4 14 Fold:TIM beta/alpha-barrel Superfamily:FAD-linked oxidoreductase Family:Methylenetetrahydrofolate reductase 59 c1hvxA_ not modelled 18.3 10 PDB header:hydrolase Chain: A: PDB Molecule:alpha-amylase; PDBTitle: bacillus stearothermophilus alpha-amylase 60 c3amkA_ not modelled 17.7 12 PDB header:transferase Chain: A: PDB Molecule:os06g0726400 protein; PDBTitle: structure of the starch branching enzyme i (bei) from oryza sativa l 61 d1m53a2 not modelled 17.3 10 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:Amylase, catalytic domain 62 c1uwvA_ not modelled 16.7 50 PDB header:transferase Chain: A: PDB Molecule:23s rrna (uracil-5-)-methyltransferase ruma; PDBTitle: crystal structure of ruma, the iron-sulfur cluster2 containing e. coli 23s ribosomal rna 5-methyluridine3 methyltransferase 63 d2guya2 not modelled 16.5 17 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:Amylase, catalytic domain 64 c2gdvA_ not modelled 15.9 7 PDB header:transferase Chain: A: PDB Molecule:sucrose phosphorylase; PDBTitle: sucrose phosphorylase from bifidobacterium adolescentis2 reacted with sucrose 65 c3aerB_ not modelled 15.9 19 PDB header:oxidoreductase Chain: B: PDB Molecule:light-independent protochlorophyllide reductase subunit b; PDBTitle: structure of the light-independent protochlorophyllide reductase2 catalyzing a key reduction for greening in the dark 66 c1zjaB_ not modelled 15.8 15 PDB header:isomerase Chain: B: PDB Molecule:trehalulose synthase; PDBTitle: crystal structure of the trehalulose synthase mutb from2 pseudomonas mesoacidophila mx-45 (triclinic form) 67 c1e40A_ not modelled 15.5 15 PDB header:hydrolase Chain: A: PDB Molecule:alpha-amylase; PDBTitle: tris/maltotriose complex of chimaeric amylase from b.2 amyloliquefaciens and b. licheniformis at 2.2a 68 c2taaA_ not modelled 15.0 15 PDB header:hydrolase (o-glycosyl) Chain: A: PDB Molecule:taka-amylase a; PDBTitle: structure and possible catalytic residues of taka-amylase a 69 c1m53A_ not modelled 15.0 10 PDB header:isomerase Chain: A: PDB Molecule:isomaltulose synthase; PDBTitle: crystal structure of isomaltulose synthase (pali) from2 klebsiella sp. lx3 70 c3a47A_ not modelled 14.6 15 PDB header:hydrolase Chain: A: PDB Molecule:oligo-1,6-glucosidase; PDBTitle: crystal structure of isomaltase from saccharomyces cerevisiae 71 d2b8na1 not modelled 14.4 16 Fold:GckA/TtuD-like Superfamily:GckA/TtuD-like Family:GckA/TtuD-like 72 c2ze0A_ not modelled 14.3 15 PDB header:hydrolase Chain: A: PDB Molecule:alpha-glucosidase; PDBTitle: alpha-glucosidase gsj 73 d1r7aa2 not modelled 13.9 7 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:Amylase, catalytic domain 74 c3lwdA_ not modelled 13.7 13 PDB header:hydrolase Chain: A: PDB Molecule:6-phosphogluconolactonase; PDBTitle: crystal structure of putative 6-phosphogluconolactonase (yp_574786.1)2 from chromohalobacter salexigens dsm 3043 at 1.88 a resolution 75 d1eh9a3 not modelled 13.7 19 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:Amylase, catalytic domain 76 d2a6na1 not modelled 13.4 14 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 77 d1qhoa4 not modelled 13.1 14 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:Amylase, catalytic domain 78 c2g7zB_ not modelled 12.9 9 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:conserved hypothetical protein spy1493; PDBTitle: conserved degv-like protein of unknown function from streptococcus2 pyogenes m1 gas binds long-chain fatty acids 79 c1jdaA_ not modelled 12.8 6 PDB header:hydrolase Chain: A: PDB Molecule:1,4-alpha maltotetrahydrolase; PDBTitle: maltotetraose-forming exo-amylase 80 c2r8wB_ not modelled 12.7 17 PDB header:lyase Chain: B: PDB Molecule:agr_c_1641p; PDBTitle: the crystal structure of dihydrodipicolinate synthase (atu0899) from2 agrobacterium tumefaciens str. c58 81 d2aeua1 not modelled 12.5 6 Fold:PLP-dependent transferase-like Superfamily:PLP-dependent transferases Family:SelA-like 82 d1o98a1 not modelled 12.5 8 Fold:2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain Superfamily:2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain Family:2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain 83 c1lwhA_ not modelled 12.4 17 PDB header:transferase Chain: A: PDB Molecule:4-alpha-glucanotransferase; PDBTitle: crystal structure of t. maritima 4-alpha-glucanotransferase 84 c3p6lA_ not modelled 12.3 10 PDB header:isomerase Chain: A: PDB Molecule:sugar phosphate isomerase/epimerase; PDBTitle: crystal structure of a sugar phosphate isomerase/epimerase (bdi_1903)2 from parabacteroides distasonis atcc 8503 at 1.85 a resolution 85 c3lciA_ not modelled 12.0 15 PDB header:lyase Chain: A: PDB Molecule:n-acetylneuraminate lyase; PDBTitle: the d-sialic acid aldolase mutant v251w 86 d2bhua3 not modelled 12.0 23 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:Amylase, catalytic domain 87 c2aaaA_ not modelled 11.9 15 PDB header:glycosidase Chain: A: PDB Molecule:alpha-amylase; PDBTitle: calcium binding in alpha-amylases: an x-ray diffraction2 study at 2.1 angstroms resolution of two enzymes from3 aspergillus 88 c1rrqA_ not modelled 11.7 18 PDB header:hydrolase/dna Chain: A: PDB Molecule:muty; PDBTitle: muty adenine glycosylase in complex with dna containing an2 a:oxog pair 89 c1uokA_ not modelled 11.5 12 PDB header:glucosidase Chain: A: PDB Molecule:oligo-1,6-glucosidase; PDBTitle: crystal structure of b. cereus oligo-1,6-glucosidase 90 c3faxA_ not modelled 11.4 24 PDB header:hydrolase Chain: A: PDB Molecule:reticulocyte binding protein; PDBTitle: the crystal structure of gbs pullulanase sap in complex with2 maltotetraose 91 d1hvxa2 not modelled 11.4 10 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:Amylase, catalytic domain 92 c2p0oA_ not modelled 11.4 6 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein duf871; PDBTitle: crystal structure of a conserved protein from locus ef_2437 in2 enterococcus faecalis with an unknown function 93 c3czkA_ not modelled 11.1 13 PDB header:hydrolase Chain: A: PDB Molecule:sucrose hydrolase; PDBTitle: crystal structure analysis of sucrose hydrolase(suh) e322q-2 sucrose complex 94 d1g5aa2 not modelled 11.1 6 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:Amylase, catalytic domain 95 c2fhfA_ not modelled 11.1 28 PDB header:hydrolase Chain: A: PDB Molecule:pullulanase; PDBTitle: crystal structure analysis of klebsiella pneumoniae2 pullulanase complexed with maltotetraose 96 c2vs1A_ not modelled 11.0 27 PDB header:transferase Chain: A: PDB Molecule:uncharacterized rna methyltransferase pyrab10780; PDBTitle: the crystal structure of pyrococcus abyssi trna (uracil-54,2 c5)-methyltransferase in complex with s-adenosyl-l-3 homocysteine 97 c3b4uB_ not modelled 10.9 15 PDB header:lyase Chain: B: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from agrobacterium2 tumefaciens str. c58 98 c3e96B_ not modelled 10.9 13 PDB header:lyase Chain: B: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from2 bacillus clausii 99 d1t6t1_ not modelled 10.9 16 Fold:Toprim domain Superfamily:Toprim domain Family:Toprim domain

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0