Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionQ64010
DateWed Jul 10 14:42:12 BST 2013
Unique Job IDd3390f452468c9b5
SequenceMAGNFDSEER ... Download FASTA

Summary 

Top model
Image coloured by rainbow N → C terminus
Model dimensions (Å):X:59.816 Y:49.217 Z:54.169
Model (left) based on template c2eyzA_
Top template information
PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform ii
Confidence and coverage
Confidence:100.0% Coverage:100%
304 residues (100% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MAGNFDSEERSSWYWGRLSRQEAVALLQGQRHGVFLVRDSSTSPGDYVLSVSENSRVSHY
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Disorder  ???????




















































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   .........70.........80.........90.........100.........110.........120
Sequence  IINSSGPRPPVPPSPAQPPPGVSPSRLRIGDQEFDSLPALLEFYKIHYLDTTTLIEPVAR
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Disorder 





????


?
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   .........130.........140.........150.........160.........170.........180
Sequence  SRQGSGVILRQEEAEYVRALFDFNGNDEEDLPFKKGDILRIRDKPEEQWWNAEDSEGKRG
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Disorder 


???????????









?
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   .........190.........200.........210.........220.........230.........240
Sequence  MIPVPYVEKYRPASASVSALIGGNQEGSHPQPLGGPEPGPYAQPSVNTPLPNLQNGPIYA
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Disorder 










?????????????????????????????????????????????



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   .........250.........260.........270.........280.........290.........300
Sequence  RVIQKRVPNAYDKTALALEVGELVKVTKINVSGQWEGECNGKRGHFPFTHVRLLDQQNPD
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Disorder 










???






































???
???
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   ....
Sequence  EDFS
Secondary structure 



SS confidence 



Disorder  ????
Disorder confidence 



 

Confidence Key
High(9)                    Low (0)
?Disordered ( 36%)
Alpha helix ( 10%)
Beta strand ( 24%)

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 2eyz chain A

3D model

Region: 1 - 304
Aligned: 304
Modelled: 304
Confidence: 100.0%
Identity: 99%
PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform ii

Phyre2

PDB 2lqn chain A

3D model

Region: 1 - 302
Aligned: 285
Modelled: 285
Confidence: 100.0%
Identity: 62%
PDB header:signaling protein
Chain: A: PDB Molecule:crk-like protein;
PDBTitle: solution structure of crkl

Phyre2

PDB 2dvj chain A

3D model

Region: 1 - 227
Aligned: 227
Modelled: 227
Confidence: 100.0%
Identity: 96%
PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog,
PDBTitle: phosphorylated crk-ii

Phyre2

PDB 2eyy chain A

3D model

Region: 1 - 204
Aligned: 204
Modelled: 204
Confidence: 100.0%
Identity: 100%
PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform i

Phyre2

PDB 3qwy chain A

3D model

Region: 4 - 190
Aligned: 165
Modelled: 176
Confidence: 100.0%
Identity: 38%
PDB header:signaling protein
Chain: A: PDB Molecule:cell death abnormality protein 2;
PDBTitle: ced-2

Phyre2

PDB 3qwx chain X

3D model

Region: 4 - 190
Aligned: 165
Modelled: 176
Confidence: 100.0%
Identity: 38%
PDB header:signaling protein
Chain: X: PDB Molecule:cell death abnormality protein 2;
PDBTitle: ced-2 1-174

Phyre2

PDB 2l3s chain A

3D model

Region: 134 - 296
Aligned: 163
Modelled: 163
Confidence: 100.0%
Identity: 91%
PDB header:structural protein
Chain: A: PDB Molecule:autoinhibited crk protein;
PDBTitle: structure of the autoinhibited crk

Phyre2

PDB 1gri chain A

3D model

Region: 136 - 298
Aligned: 157
Modelled: 163
Confidence: 100.0%
Identity: 24%
PDB header:signal transduction adaptor
Chain: A: PDB Molecule:growth factor bound protein 2;
PDBTitle: grb2

Phyre2

PDB 1ng2 chain A

3D model

Region: 134 - 301
Aligned: 133
Modelled: 134
Confidence: 100.0%
Identity: 20%
PDB header:oxidoreductase activator
Chain: A: PDB Molecule:neutrophil cytosolic factor 1;
PDBTitle: structure of autoinhibited p47phox

Phyre2

PDB 1ov3 chain A

3D model

Region: 129 - 293
Aligned: 130
Modelled: 131
Confidence: 100.0%
Identity: 24%
PDB header:oxidoreductase activator
Chain: A: PDB Molecule:neutrophil cytosol factor 1;
PDBTitle: structure of the p22phox-p47phox complex

Phyre2

PDB 2eyv chain A domain 1

3D model

Region: 12 - 120
Aligned: 109
Modelled: 109
Confidence: 99.9%
Identity: 99%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2

PDB 2eo3 chain A

3D model

Region: 2 - 120
Aligned: 102
Modelled: 102
Confidence: 99.9%
Identity: 78%
PDB header:signaling protein
Chain: A: PDB Molecule:crk-like protein;
PDBTitle: solution structure of the sh2 domain from human crk-like2 protein

Phyre2

PDB 3hiz chain B

3D model

Region: 7 - 123
Aligned: 100
Modelled: 100
Confidence: 99.9%
Identity: 30%
PDB header:transferase/oncoprotein
Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit
PDBTitle: crystal structure of p110alpha h1047r mutant in complex with2 nish2 of p85alpha

Phyre2

PDB 2oq1 chain A domain 1

3D model

Region: 6 - 128
Aligned: 107
Modelled: 107
Confidence: 99.9%
Identity: 27%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2

PDB 2shp chain A

3D model

Region: 9 - 171
Aligned: 145
Modelled: 146
Confidence: 99.8%
Identity: 23%
PDB header:tyrosine phosphatase
Chain: A: PDB Molecule:shp-2;
PDBTitle: tyrosine phosphatase shp-2

Phyre2

PDB 2oq1 chain A

3D model

Region: 6 - 126
Aligned: 105
Modelled: 105
Confidence: 99.8%
Identity: 28%
PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase zap-70;
PDBTitle: tandem sh2 domains of zap-70 with 19-mer zeta1 peptide

Phyre2

PDB 2y3a chain B

3D model

Region: 1 - 126
Aligned: 109
Modelled: 110
Confidence: 99.8%
Identity: 28%
PDB header:transferase
Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit beta;
PDBTitle: crystal structure of p110beta in complex with icsh2 of p85beta and2 the drug gdc-0941

Phyre2

PDB 2gsb chain A

3D model

Region: 6 - 128
Aligned: 106
Modelled: 106
Confidence: 99.8%
Identity: 28%
PDB header:signaling protein
Chain: A: PDB Molecule:ras gtpase-activating protein 1;
PDBTitle: solution structure of the second sh2 domain of human ras2 gtpase-activating protein 1

Phyre2

PDB 3gqi chain B

3D model

Region: 11 - 136
Aligned: 113
Modelled: 113
Confidence: 99.8%
Identity: 34%
PDB header:transferase/transferase inhibitor
Chain: B: PDB Molecule:phospholipase c-gamma-1;
PDBTitle: crystal structure of activated receptor tyrosine kinase in complex2 with substrates

Phyre2

PDB 2b3o chain A

3D model

Region: 13 - 175
Aligned: 145
Modelled: 146
Confidence: 99.8%
Identity: 27%
PDB header:hydrolase
Chain: A: PDB Molecule:tyrosine-protein phosphatase, non-receptor type
PDBTitle: crystal structure of human tyrosine phosphatase shp-1

Phyre2
1

c2eyzA_
2

c2lqnA_
3

c2dvjA_
4

c2eyyA_
5

c3qwyA_
6

c3qwxX_
7

c2l3sA_
8

c1griA_
9

c1ng2A_
10

c1ov3A_
11

d2eyva1
12

c2eo3A_
13

c3hizB_
14

d2oq1a1
15

c2shpA_
16

c2oq1A_
17

c2y3aB_
18

c2gsbA_
19

c3gqiB_
20

c2b3oA_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c2eyzA_



100.0 99 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform ii
2c2lqnA_



100.0 62 PDB header:signaling protein
Chain: A: PDB Molecule:crk-like protein;
PDBTitle: solution structure of crkl
3c2dvjA_



100.0 96 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog,
PDBTitle: phosphorylated crk-ii
4c2eyyA_



100.0 100 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform i
5c3qwyA_



100.0 38 PDB header:signaling protein
Chain: A: PDB Molecule:cell death abnormality protein 2;
PDBTitle: ced-2
6c3qwxX_



100.0 38 PDB header:signaling protein
Chain: X: PDB Molecule:cell death abnormality protein 2;
PDBTitle: ced-2 1-174
7c2l3sA_



100.0 91 PDB header:structural protein
Chain: A: PDB Molecule:autoinhibited crk protein;
PDBTitle: structure of the autoinhibited crk
8c1griA_



100.0 24 PDB header:signal transduction adaptor
Chain: A: PDB Molecule:growth factor bound protein 2;
PDBTitle: grb2
9c1ng2A_



100.0 20 PDB header:oxidoreductase activator
Chain: A: PDB Molecule:neutrophil cytosolic factor 1;
PDBTitle: structure of autoinhibited p47phox
10c1ov3A_



100.0 24 PDB header:oxidoreductase activator
Chain: A: PDB Molecule:neutrophil cytosol factor 1;
PDBTitle: structure of the p22phox-p47phox complex
11d2eyva1



99.9 99 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
12c2eo3A_



99.9 78 PDB header:signaling protein
Chain: A: PDB Molecule:crk-like protein;
PDBTitle: solution structure of the sh2 domain from human crk-like2 protein
13c3hizB_



99.9 30 PDB header:transferase/oncoprotein
Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit
PDBTitle: crystal structure of p110alpha h1047r mutant in complex with2 nish2 of p85alpha
14d2oq1a1



99.9 27 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
15c2shpA_



99.8 23 PDB header:tyrosine phosphatase
Chain: A: PDB Molecule:shp-2;
PDBTitle: tyrosine phosphatase shp-2
16c2oq1A_



99.8 28 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase zap-70;
PDBTitle: tandem sh2 domains of zap-70 with 19-mer zeta1 peptide
17c2y3aB_



99.8 28 PDB header:transferase
Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit beta;
PDBTitle: crystal structure of p110beta in complex with icsh2 of p85beta and2 the drug gdc-0941
18c2gsbA_



99.8 28 PDB header:signaling protein
Chain: A: PDB Molecule:ras gtpase-activating protein 1;
PDBTitle: solution structure of the second sh2 domain of human ras2 gtpase-activating protein 1
19c3gqiB_



99.8 34 PDB header:transferase/transferase inhibitor
Chain: B: PDB Molecule:phospholipase c-gamma-1;
PDBTitle: crystal structure of activated receptor tyrosine kinase in complex2 with substrates
20c2b3oA_



99.8 27 PDB header:hydrolase
Chain: A: PDB Molecule:tyrosine-protein phosphatase, non-receptor type
PDBTitle: crystal structure of human tyrosine phosphatase shp-1
21c2fo0A_



not modelled 99.8 32 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase abl1 (1b isoform);
PDBTitle: organization of the sh3-sh2 unit in active and inactive forms of the2 c-abl tyrosine kinase
22d1a81a1



not modelled 99.8 22 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
23c1mv3A_



not modelled 99.8 15 PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:myc box dependent interacting protein 1;
PDBTitle: nmr structure of the tumor suppressor bin1: alternative2 splicing in melanoma and interaction with c-myc
24c2eo6A_



not modelled 99.8 27 PDB header:signaling protein
Chain: A: PDB Molecule:b-cell linker protein;
PDBTitle: solution structure of the sh2 domain from mouse b-cell2 linker protein blnk
25c2crhA_



not modelled 99.8 25 PDB header:signaling protein
Chain: A: PDB Molecule:vav proto-oncogene;
PDBTitle: solution structure of the sh2 domain of human proto-2 oncogene protein vav1
26d2izva2



not modelled 99.8 26 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
27c2dlyA_



not modelled 99.8 25 PDB header:transferase
Chain: A: PDB Molecule:fyn-related kinase;
PDBTitle: solution structure of the sh2 domain of murine fyn-related2 kinase
28d1pica_



not modelled 99.8 33 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
29c2dbkA_



not modelled 99.8 65 PDB header:signaling protein
Chain: A: PDB Molecule:crk-like protein;
PDBTitle: solution structures of the sh3 domain of human crk-like2 protein
30c2ozoA_



not modelled 99.8 28 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase zap-70;
PDBTitle: autoinhibited intact human zap-70
31d1fhsa_



not modelled 99.8 22 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
32c2ysxA_



not modelled 99.8 28 PDB header:signaling protein
Chain: A: PDB Molecule:signaling inositol polyphosphate phosphatase
PDBTitle: solution structure of the human ship sh2 domain
33c2ablA_



not modelled 99.8 35 PDB header:transferase
Chain: A: PDB Molecule:abl tyrosine kinase;
PDBTitle: sh3-sh2 domain fragment of human bcr-abl tyrosine kinase
34c2hdxB_



not modelled 99.8 33 PDB header:signaling protein
Chain: B: PDB Molecule:sh2-b ph domain containing signaling mediator 1
PDBTitle: crystal structure of the src homology-2 domain of sh2-b in2 complex with jak2 ptyr813 phosphopeptide
35c2dlzA_



not modelled 99.8 27 PDB header:signaling protein
Chain: A: PDB Molecule:protein vav-2;
PDBTitle: solution structure of the sh2 domain of human protein vav-2
36d1opka2



not modelled 99.8 35 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
37d2oq1a2



not modelled 99.8 32 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
38d1a81e1



not modelled 99.8 23 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
39d1blja_



not modelled 99.8 28 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
40c4fl2A_



not modelled 99.8 22 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase syk;
PDBTitle: structural and biophysical characterization of the syk activation2 switch
41d1udla_



not modelled 99.8 25 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
42c1ka6A_



not modelled 99.8 22 PDB header:immune system
Chain: A: PDB Molecule:sh2 domain protein 1a;
PDBTitle: sap/sh2d1a bound to peptide n-py
43d1csya_



not modelled 99.8 27 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
44d3c7ia1



not modelled 99.8 28 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
45d1r1qa_



not modelled 99.8 29 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
46d1a81e2



not modelled 99.8 28 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
47d1rjaa_



not modelled 99.8 34 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
48c2vifA_



not modelled 99.8 24 PDB header:signaling protein
Chain: A: PDB Molecule:suppressor of cytokine signalling 6;
PDBTitle: crystal structure of socs6 sh2 domain in complex with a c-kit2 phosphopeptide
49c1oplA_



not modelled 99.8 31 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase;
PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase
50c2ci8A_



not modelled 99.8 31 PDB header:translation
Chain: A: PDB Molecule:cytoplasmic protein nck1;
PDBTitle: sh2 domain of human nck1 adaptor protein - uncomplexed
51c3ps5A_



not modelled 99.8 36 PDB header:hydrolase, signaling protein
Chain: A: PDB Molecule:tyrosine-protein phosphatase non-receptor type 6;
PDBTitle: crystal structure of the full-length human protein tyrosine2 phosphatase shp-1
52c2c9wA_



not modelled 99.8 25 PDB header:transcription regulation
Chain: A: PDB Molecule:suppressor of cytokine signaling 2;
PDBTitle: crystal structure of socs-2 in complex with elongin-b and2 elongin-c at 1.9a resolution
53d2shpa2



not modelled 99.8 30 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
54d1jyra_



not modelled 99.8 29 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
55c1k9aB_



not modelled 99.8 32 PDB header:transferase
Chain: B: PDB Molecule:carboxyl-terminal src kinase;
PDBTitle: crystal structure analysis of full-length carboxyl-terminal2 src kinase at 2.5 a resolution
56c2hmhA_



not modelled 99.8 25 PDB header:cytokine regulator
Chain: A: PDB Molecule:suppressor of cytokine signaling 3;
PDBTitle: crystal structure of socs3 in complex with gp130(ptyr757)2 phosphopeptide.
57d1nrva_



not modelled 99.8 28 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
58c2lctA_



not modelled 99.8 28 PDB header:signaling protein
Chain: A: PDB Molecule:proto-oncogene vav;
PDBTitle: solution structure of the vav1 sh2 domain complexed with a syk-derived2 doubly phosphorylated peptide
59d2cs0a1



not modelled 99.8 28 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
60d2c9wa2



not modelled 99.8 26 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
61d1a81a2



not modelled 99.8 28 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
62d1rpya_



not modelled 99.8 29 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
63c2eobA_



not modelled 99.8 28 PDB header:hydrolase
Chain: A: PDB Molecule:1-phosphatidylinositol-4,5-bisphosphate
PDBTitle: solution structure of the second sh2 domain from rat plc2 gamma-2
64d1d4ta_



not modelled 99.8 23 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
65c2eyxA_



not modelled 99.8 100 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: c-terminal sh3 domain of ct10-regulated kinase
66d1k9aa2



not modelled 99.8 33 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
67d1lkka_



not modelled 99.8 32 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
68c2augB_



not modelled 99.8 33 PDB header:signaling protein
Chain: B: PDB Molecule:growth factor receptor-bound protein 14;
PDBTitle: crystal structure of the grb14 sh2 domain
69d1jwoa_



not modelled 99.8 34 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
70d1xa6a2



not modelled 99.8 23 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
71c1y57A_



not modelled 99.8 32 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor
72c1x6cA_



not modelled 99.8 36 PDB header:signaling protein
Chain: A: PDB Molecule:tyrosine-protein phosphatase, non-receptor type
PDBTitle: solution structures of the sh2 domain of human protein-2 tyrosine phosphatase shp-1
73c2izvA_



not modelled 99.8 25 PDB header:transcription
Chain: A: PDB Molecule:suppressor of cytokine signaling 4;
PDBTitle: crystal structure of socs-4 in complex with elongin-b and2 elongin-c at 2.55a resolution
74c2kk6A_



not modelled 99.8 29 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fer;
PDBTitle: solution structure of sh2 domain of proto-oncogene tyrosine-2 protein kinase fer from homo sapiens, northeast structural3 genomics consortium (nesg) target hr3461d
75c2el8A_



not modelled 99.8 24 PDB header:signaling protein
Chain: A: PDB Molecule:signal-transducing adaptor protein 2;
PDBTitle: solution structure of the human stap2 sh2 domain
76c3jv3A_



not modelled 99.8 26 PDB header:protein binding
Chain: A: PDB Molecule:intersectin-1;
PDBTitle: structure of sh3e-dh unit of murine intersectin-1l
77c3nhnA_



not modelled 99.8 34 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase hck;
PDBTitle: crystal structure of the src-family kinase hck sh3-sh2-linker2 regulatory region
78d1ayaa_



not modelled 99.8 33 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
79c1x27F_



not modelled 99.7 27 PDB header:signaling protein
Chain: F: PDB Molecule:proto-oncogene tyrosine-protein kinase lck;
PDBTitle: crystal structure of lck sh2-sh3 with sh2 binding site of2 p130cas
80c2ge9A_



not modelled 99.7 30 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase btk;
PDBTitle: solution structures of the sh2 domain of bruton's tyrosine2 kinase
81c2knoA_



not modelled 99.7 25 PDB header:hydrolase
Chain: A: PDB Molecule:tensin-like c1 domain-containing phosphatase;
PDBTitle: nmr solution structure of sh2 domain of the human tensin like c12 domain containing phosphatase (tenc1)
82d1luia_



not modelled 99.7 33 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
83d1o48a_



not modelled 99.7 34 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
84c2dcrA_



not modelled 99.7 31 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fes/fps;
PDBTitle: fully automated solution structure determination of the fes2 sh2 domain
85c2ebpA_



not modelled 99.7 27 PDB header:cell adhesion
Chain: A: PDB Molecule:sam and sh3 domain-containing protein 1;
PDBTitle: solution structure of the sh3 domain from human sam and sh32 domain containing protein 1
86d1bkla_



not modelled 99.7 34 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
87d1i3za_



not modelled 99.7 32 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
88d1g83a2



not modelled 99.7 31 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
89d1qcfa2



not modelled 99.7 34 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
90c1a81E_



not modelled 99.7 23 PDB header:complex (transferase/peptide)
Chain: E: PDB Molecule:syk kinase;
PDBTitle: crystal structure of the tandem sh2 domain of the syk kinase bound to2 a dually tyrosine-phosphorylated itam
91d1ng2a2



not modelled 99.7 16 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
92d2shpa3



not modelled 99.7 38 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
93c2ed0A_



not modelled 99.7 22 PDB header:signaling protein
Chain: A: PDB Molecule:abl interactor 2;
PDBTitle: solution structure of the sh3 domain of abl interactor 22 (abelson interactor 2)
94c2h8hA_



not modelled 99.7 32 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: src kinase in complex with a quinazoline inhibitor
95c2dx1A_



not modelled 99.7 21 PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 4;
PDBTitle: crystal structure of rhogef protein asef
96c1rqqC_



not modelled 99.7 31 PDB header:transferase/signaling protein
Chain: C: PDB Molecule:adaptor protein aps;
PDBTitle: crystal structure of the insulin receptor kinase in complex2 with the sh2 domain of aps
97d1fu6a_



not modelled 99.7 28 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
98d1cwea_



not modelled 99.7 35 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
99d1mila_



not modelled 99.7 34 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
100c2c0iA_



not modelled 99.7 30 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase hck;
PDBTitle: src family kinase hck with bound inhibitor a-420983
101d1f2fa_



not modelled 99.7 34 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
102d2qmsa1



not modelled 99.7 29 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
103c2bzxA_



not modelled 99.7 69 PDB header:sh3 domain
Chain: A: PDB Molecule:crk-like protein;
PDBTitle: atomic model of crkl-sh3c monomer
104d1qada_



not modelled 99.7 34 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
105c3nmzD_



not modelled 99.7 18 PDB header:cell adhesion/cell cycle
Chain: D: PDB Molecule:rho guanine nucleotide exchange factor 4;
PDBTitle: crytal structure of apc complexed with asef
106c3gxxB_



not modelled 99.7 17 PDB header:transcription
Chain: B: PDB Molecule:transcription elongation factor spt6;
PDBTitle: structure of the sh2 domain of the candida glabrata2 transcription elongation factor spt6, crystal form b
107d2fcia1



not modelled 99.7 31 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
108c2cubA_



not modelled 99.7 23 PDB header:signaling protein
Chain: A: PDB Molecule:cytoplasmic protein nck1;
PDBTitle: solution structure of the sh3 domain of the human2 cytoplasmic protein nck1
109c2rqrA_



not modelled 99.7 11 PDB header:protein binding
Chain: A: PDB Molecule:engulfment and cell motility protein 1, linker, dedicator
PDBTitle: the solution structure of human dock2 sh3 domain - elmo1 peptide2 chimera complex
110c2bz8B_



not modelled 99.7 32 PDB header:sh3 domain
Chain: B: PDB Molecule:sh3-domain kinase binding protein 1;
PDBTitle: n-terminal sh3 domain of cin85 bound to cbl-b peptide
111c2oi3A_



not modelled 99.7 16 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase hck;
PDBTitle: nmr structure analysis of the hematopoetic cell kinase sh32 domain complexed with an artificial high affinity ligand3 (pd1)
112c2dybA_



not modelled 99.7 20 PDB header:oxidoreductase
Chain: A: PDB Molecule:neutrophil cytosol factor 4;
PDBTitle: the crystal structure of human p40(phox)
113c1g83A_



not modelled 99.7 33 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fyn;
PDBTitle: crystal structure of fyn sh3-sh2
114c2nwmA_



not modelled 99.7 27 PDB header:cell adhesion
Chain: A: PDB Molecule:vinexin;
PDBTitle: solution structure of the first sh3 domain of human vinexin2 and its interaction with the peptides from vinculin
115c1x2qA_



not modelled 99.7 19 PDB header:signaling protein
Chain: A: PDB Molecule:signal transducing adapter molecule 2;
PDBTitle: solution structure of the sh3 domain of the signal2 transducing adaptor molecule 2
116c2djqA_



not modelled 99.7 18 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:sh3 domain containing ring finger 2;
PDBTitle: the solution structure of the first sh3 domain of mouse sh32 domain containing ring finger 2
117c4igzA_



not modelled 99.7 20 PDB header:protein binding
Chain: A: PDB Molecule:sorbin and sh3 domain-containing protein 2;
PDBTitle: crystal structure of the sh3 domain of human sorbin and sh3 domain-2 containing protein 2
118c2yuoA_



not modelled 99.7 23 PDB header:signaling protein
Chain: A: PDB Molecule:run and tbc1 domain containing 3;
PDBTitle: solution structure of the sh3 domain of mouse run and tbc12 domain containing 3
119c2ekhA_



not modelled 99.7 16 PDB header:signaling protein
Chain: A: PDB Molecule:sh3 and px domain-containing protein 2a;
PDBTitle: solution structures of the sh3 domain of human kiaa0418
120c2dl8A_



not modelled 99.7 19 PDB header:signaling protein
Chain: A: PDB Molecule:slit-robo rho gtpase-activating protein 2;
PDBTitle: solution structure of the sh3 domain of human slit-robo rho2 gtpase-activating protein 2

Binding site prediction 

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