Phyre 2 Results for Q6XZF7

Email	l.a.kelley@imperial.ac.uk
Description	Q6XZF7
Date	Thu Apr 26 09:30:42 BST 2012
Unique Job ID	56338b38252c9db8

Summary

Top model

Image coloured by rainbow N → C terminus

Model (left) based on template c2dx1A_

Top template information

PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 4;
PDBTitle: crystal structure of rhogef protein asef

Confidence and coverage

Confidence:

100.0%

Coverage:

16%

258 residues ( 16% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.

Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.

863 residues ( 55%) could be modelled at >90% confidence using multiple-templates.

You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.

Warning: 61% of your sequence is predicted disordered. Disordered regions cannot be meaningfully predicted.

3D viewing

Interactive 3D view in Jmol

Sequence analysis

Secondary structure and disorder prediction

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60

Sequence M E A G S V V R A I F D F C P S V S E E L P L F V G D I I E V L A V V D E F W L L G K K E D V T G Q F P S S F V E I V T

Secondary structure

SS confidence

Disorder ? ? ? ? ?
? ?
? ? ? ? ?

Disorder confidence

. . . . . . . . . 70 . . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120

Sequence I P S L K E G E R L F V C I C E F T S Q E L D N L P L H R G D L V I L D G I P T A G W L Q G R S C W G A R G F F P S S C

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ?
? ? ? ? ? ? ? ? ? ? ? ? ?
? ?
?
?

Disorder confidence

. . . . . . . . . 130 . . . . . . . . . 140 . . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180

Sequence V R E L C L S S Q S R Q W H S Q S A L F Q I P E Y S M G Q A R A L M G L S A Q L D E E L D F R E G D V I T I I G V P E P

Secondary structure

SS confidence

Disorder
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?
? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210 . . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240

Sequence G W F E G E L E G R R G I F P E G F V E L L G P L R T V D E S V S S G N Q D D C I V N G E V D T P V G E E E I G P D E D

Secondary structure

SS confidence

Disorder
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280 . . . . . . . . . 290 . . . . . . . . . 300

Sequence E E E P G T Y G V A L Y R F Q A L E P N E L D F E V G D K I R I L A T L E D G W L E G S L K G R T G I F P Y R F V K L C

Secondary structure

SS confidence

Disorder ? ?
?
? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 . . . . . . . . . 350 . . . . . . . . . 360

Sequence P D T R V E E T M A L P Q E G S L A R I P E T S L D C L E N T L G V E E Q R H E T S D H E A E E P D C I I S E A P T S P

Secondary structure

SS confidence

Disorder
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 370 . . . . . . . . . 380 . . . . . . . . . 390 . . . . . . . . . 400 . . . . . . . . . 410 . . . . . . . . . 420

Sequence L G H L T S E Y D T D R N S Y Q D E D T A G G P P R S P G V E W E M P L A T D S P T S D P T E V V N G I S S Q P Q V P F

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 430 . . . . . . . . . 440 . . . . . . . . . 450 . . . . . . . . . 460 . . . . . . . . . 470 . . . . . . . . . 480

Sequence H P N L Q K S Q Y Y S T V G G S H P H S E Q Y P D L L P L E A R T R D Y A S L P P K R M Y S Q L K T L Q K P V L P L Y R

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 490 . . . . . . . . . 500 . . . . . . . . . 510 . . . . . . . . . 520 . . . . . . . . . 530 . . . . . . . . . 540

Sequence G S S V S A S R V V K P R Q S S P Q L H N L A S Y T K K H H T S S V Y S I S E R L E M K P G P Q A Q G L V M E A A T H S

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?
?
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 550 . . . . . . . . . 560 . . . . . . . . . 570 . . . . . . . . . 580 . . . . . . . . . 590 . . . . . . . . . 600

Sequence Q G D G S T D L D S K L T Q Q L I E F E K S L A G P G T E P D K I L R H F S I M D F N S E K D I V R G S S K L I T E Q E

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 610 . . . . . . . . . 620 . . . . . . . . . 630 . . . . . . . . . 640 . . . . . . . . . 650 . . . . . . . . . 660

Sequence L P E R R K A L R P P P P R P C T P V S T S P H L L V D Q N L K P A P P L V V R P S R P A P L P P S A Q Q R T N A V S P

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 670 . . . . . . . . . 680 . . . . . . . . . 690 . . . . . . . . . 700 . . . . . . . . . 710 . . . . . . . . . 720

Sequence K L L S R H R P T C E T L E K E G P G H M G R S L D Q T S P C P L V L V R I E E M E R D L D M Y S R A Q E E L N L M L E

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?
?

Disorder confidence

. . . . . . . . . 730 . . . . . . . . . 740 . . . . . . . . . 750 . . . . . . . . . 760 . . . . . . . . . 770 . . . . . . . . . 780

Sequence E K Q D E S S R A E T L E D L K F C E S N I E S L N M E L Q Q L R E M T L L S S Q S S S L V A P S G S V S A E N P E Q R

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 790 . . . . . . . . . 800 . . . . . . . . . 810 . . . . . . . . . 820 . . . . . . . . . 830 . . . . . . . . . 840

Sequence M L E K R A K V I E E L L Q T E R D Y I R D L E M C I E R I M V P M Q Q A Q V P N I D F E G L F G N M Q M V I K V S K Q

Secondary structure

SS confidence

Disorder
? ? ? ?

Disorder confidence

. . . . . . . . . 850 . . . . . . . . . 860 . . . . . . . . . 870 . . . . . . . . . 880 . . . . . . . . . 890 . . . . . . . . . 900

Sequence L L A A L E I S D A V G P V F L G H R D E L E G T Y K I Y C Q N H D E A I A L L E I Y E K D E K I Q K H L Q D S L A D L

Secondary structure

SS confidence

Disorder

Disorder confidence

. . . . . . . . . 910 . . . . . . . . . 920 . . . . . . . . . 930 . . . . . . . . . 940 . . . . . . . . . 950 . . . . . . . . . 960

Sequence K S L Y N E W G C T N Y I N L G S F L I K P V Q R V M R Y P L L L M E L L N S T P E S H P D K V P L T N A V L A V K E I

Secondary structure

SS confidence

Disorder
? ? ? ? ? ? ? ? ?
?
?

Disorder confidence

. . . . . . . . . 970 . . . . . . . . . 980 . . . . . . . . . 990 . . . . . . . . . 1000 . . . . . . . . . 1010 . . . . . . . . . 1020

Sequence N V N I N E Y K R R K D L V L K Y R K G D E D S L M E K I S K L N I H S I I K K S N R V S S H L K H L T G F A P Q I K D

Secondary structure

SS confidence

Disorder
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?
? ? ? ? ? ? ? ? ? ?
? ?
? ? ? ? ?

Disorder confidence

. . . . . . . . . 1030 . . . . . . . . . 1040 . . . . . . . . . 1050 . . . . . . . . . 1060 . . . . . . . . . 1070 . . . . . . . . . 1080

Sequence E V F E E T E K N F R M Q E R L I K S F I R D L S L Y L Q H I R E S A C V K V V A A V S M W D V C M E R G H R D L E Q F

Secondary structure

SS confidence

Disorder
? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 1090 . . . . . . . . . 1100 . . . . . . . . . 1110 . . . . . . . . . 1120 . . . . . . . . . 1130 . . . . . . . . . 1140

Sequence E R V H R Y I S D Q L F T N F K E R T E R L V I S P L N Q L L S M F T G P H K L V Q K R F D K L L D F Y N C T E R A E K

Secondary structure

SS confidence

Disorder
?
? ? ?

Disorder confidence

. . . . . . . . . 1150 . . . . . . . . . 1160 . . . . . . . . . 1170 . . . . . . . . . 1180 . . . . . . . . . 1190 . . . . . . . . . 1200

Sequence L K D K K T L E E L Q S A R N N Y E A L N A Q L L D E L P K F H Q Y A Q G L F T N C V H G Y A E A H C D F V H Q A L E Q

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ?
? ?
? ? ?

Disorder confidence

. . . . . . . . . 1210 . . . . . . . . . 1220 . . . . . . . . . 1230 . . . . . . . . . 1240 . . . . . . . . . 1250 . . . . . . . . . 1260

Sequence L K P L L S L L K V A G R E G N L I A I F H E E H S R V L Q Q L Q V F T F F P E S L P A T K K P F E R K T I D R Q S A R

Secondary structure

SS confidence

Disorder
? ? ? ? ? ? ? ? ? ? ? ? ? ?
? ? ? ?
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 1270 . . . . . . . . . 1280 . . . . . . . . . 1290 . . . . . . . . . 1300 . . . . . . . . . 1310 . . . . . . . . . 1320

Sequence K P L L G L P S Y M L Q S E E L R A S L L A R Y P P E K L F Q A E R N F N A A Q D L D V S L L E G D L V G V I K K K D P

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?
?
? ? ? ? ? ? ? ? ? ? ? ? ?
? ? ? ? ?
? ? ? ? ?

Disorder confidence

. . . . . . . . . 1330 . . . . . . . . . 1340 . . . . . . . . . 1350 . . . . . . . . . 1360 . . . . . . . . . 1370 . . . . . . . . . 1380

Sequence M G S Q N R W L I D N G V T K G F V Y S S F L K P Y N P R R S H S D A S V G S H S S T E S E H G S S S P R F P R Q N S G

Secondary structure

SS confidence

Disorder ? ? ? ? ?
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 1390 . . . . . . . . . 1400 . . . . . . . . . 1410 . . . . . . . . . 1420 . . . . . . . . . 1430 . . . . . . . . . 1440

Sequence S T L T F N P S S M A V S F T S G S C Q K Q P Q D A S P P P K E C D Q G T L S A S L N P S N S E S S P S R C P S D P D S

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 1450 . . . . . . . . . 1460 . . . . . . . . . 1470 . . . . . . . . . 1480 . . . . . . . . . 1490 . . . . . . . . . 1500

Sequence T S Q P R S G D S A D V A R D V K Q P T A T P R S Y R N F R H P E I V G Y S V P G R N G Q S Q D L V K G C A R T A Q A P

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 1510 . . . . . . . . . 1520 . . . . . . . . . 1530 . . . . . . . . . 1540 . . . . . . . . . 1550 . . . . . . . . . 1560

Sequence E D R S T E P D G S E A E G N Q V Y F A V Y T F K A R N P N E L S V S A N Q K L K I L E F K D V T G N T E W W L A E V N

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ? ? ?
? ? ? ? ? ?
?
?

Disorder confidence

. . . . . . . . . 1570 . . . . . . .

Sequence G K K G Y V P S N Y I R K T E Y T

Secondary structure

SS confidence

Disorder
? ? ? ? ?

Disorder confidence

Confidence Key
High(9) Low (0)

? Disordered

Alpha helix

Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank	Aligned region

PDB 2dx1 chain A

Region: 245 - 983
Aligned: 258
Modelled: 267
Confidence: 100.0%
Identity: 39%
PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 4;
PDBTitle: crystal structure of rhogef protein asef

Phyre2

PDB 1gri chain A

Region: 6 - 203
Aligned: 192
Modelled: 198
Confidence: 100.0%
Identity: 23%
PDB header:signal transduction adaptor
Chain: A: PDB Molecule:growth factor bound protein 2;
PDBTitle: grb2

Phyre2

PDB 3ky9 chain B

Region: 780 - 983
Aligned: 193
Modelled: 204
Confidence: 100.0%
Identity: 25%
PDB header:apoptosis
Chain: B: PDB Molecule:proto-oncogene vav;
PDBTitle: autoinhibited vav1

Phyre2

PDB 1ng2 chain A

Region: 6 - 124
Aligned: 118
Modelled: 119
Confidence: 99.9%
Identity: 27%
PDB header:oxidoreductase activator
Chain: A: PDB Molecule:neutrophil cytosolic factor 1;
PDBTitle: structure of autoinhibited p47phox

Phyre2

PDB 2l3s chain A

Region: 69 - 204
Aligned: 136
Modelled: 136
Confidence: 99.9%
Identity: 24%
PDB header:structural protein
Chain: A: PDB Molecule:autoinhibited crk protein;
PDBTitle: structure of the autoinhibited crk

Phyre2

PDB 1ov3 chain A

Region: 6 - 123
Aligned: 117
Modelled: 118
Confidence: 99.9%
Identity: 27%
PDB header:oxidoreductase activator
Chain: A: PDB Molecule:neutrophil cytosol factor 1;
PDBTitle: structure of the p22phox-p47phox complex

Phyre2

PDB 2eyz chain A

Region: 60 - 209
Aligned: 150
Modelled: 150
Confidence: 99.9%
Identity: 20%
PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform ii

Phyre2

PDB 2vrw chain B

Region: 780 - 983
Aligned: 193
Modelled: 204
Confidence: 99.9%
Identity: 26%
PDB header:signaling protein
Chain: B: PDB Molecule:proto-oncogene vav;
PDBTitle: critical structural role for the ph and c1 domains of the2 vav1 exchange factor

Phyre2

PDB 3ksy chain A

Region: 784 - 983
Aligned: 194
Modelled: 195
Confidence: 99.9%
Identity: 20%
PDB header:signaling protein
Chain: A: PDB Molecule:son of sevenless homolog 1;
PDBTitle: crystal structure of the histone domain, dh-ph unit, and2 catalytic unit of the ras activator son of sevenless (sos)

Phyre2

PDB 3odo chain A

Region: 760 - 983
Aligned: 215
Modelled: 224
Confidence: 99.9%
Identity: 22%
PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 1;
PDBTitle: crystal structure of the dh/ph domains of p115-rhogef

Phyre2

PDB 1xcg chain A

Region: 766 - 983
Aligned: 210
Modelled: 218
Confidence: 99.9%
Identity: 20%
PDB header:signaling protein activator/signaling pr
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 11;
PDBTitle: crystal structure of human rhoa in complex with dh/ph2 fragment of pdzrhogef

Phyre2

PDB 1foe chain A

Region: 780 - 981
Aligned: 192
Modelled: 202
Confidence: 99.9%
Identity: 29%
PDB header:signaling protein, immune system/signali
Chain: A: PDB Molecule:t-lymphoma invasion and metastasis inducing
PDBTitle: crystal structure of rac1 in complex with the guanine2 nucleotide exchange region of tiam1

Phyre2

PDB 1x86 chain A

Region: 763 - 982
Aligned: 211
Modelled: 220
Confidence: 99.9%
Identity: 19%
PDB header:signaling protein/membrane protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 12;
PDBTitle: crystal structure of the dh/ph domains of leukemia-associated rhogef2 in complex with rhoa

Phyre2

PDB 3t06 chain E

Region: 764 - 983
Aligned: 212
Modelled: 220
Confidence: 99.9%
Identity: 20%
PDB header:signaling protein
Chain: E: PDB Molecule:rho guanine nucleotide exchange factor 11;
PDBTitle: crystal structure of the dh/ph fragment of pdzrhogef with n-terminal2 regulatory elements in complex with human rhoa

Phyre2

PDB 1xcg chain A domain 1

Region: 766 - 983
Aligned: 210
Modelled: 218
Confidence: 99.9%
Identity: 20%
Fold: DBL homology domain (DH-domain)
Superfamily: DBL homology domain (DH-domain)
Family: DBL homology domain (DH-domain)

Phyre2

PDB 2dfk chain A

Region: 780 - 982
Aligned: 194
Modelled: 203
Confidence: 99.9%
Identity: 29%
PDB header:cell cycle
Chain: A: PDB Molecule:collybistin ii;
PDBTitle: crystal structure of the cdc42-collybistin ii complex

Phyre2

PDB 3bji chain A

Region: 780 - 982
Aligned: 192
Modelled: 195
Confidence: 99.9%
Identity: 25%
PDB header:signaling protein
Chain: A: PDB Molecule:proto-oncogene vav;
PDBTitle: structural basis of promiscuous guanine nucleotide exchange2 by the t-cell essential vav1

Phyre2

PDB 1xdv chain B

Region: 785 - 992
Aligned: 200
Modelled: 208
Confidence: 99.9%
Identity: 20%
PDB header:signaling protein
Chain: B: PDB Molecule:son of sevenless protein homolog 1;
PDBTitle: experimentally phased structure of human the son of2 sevenless protein at 4.1 ang.

Phyre2

PDB 1txd chain A domain 1

Region: 763 - 983
Aligned: 212
Modelled: 221
Confidence: 99.9%
Identity: 20%
Fold: DBL homology domain (DH-domain)
Superfamily: DBL homology domain (DH-domain)
Family: DBL homology domain (DH-domain)

Phyre2

PDB 2z0q chain A

Region: 780 - 979
Aligned: 178
Modelled: 179
Confidence: 99.9%
Identity: 32%
PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine nucleotide exchange factor 3;
PDBTitle: crystal structure of dh-ph domain of rhogef3(xpln)

Phyre2

PDB 1mv3 chain A

Region: 1375 - 1574
Aligned: 200
Modelled: 200
Confidence: 99.8%
Identity: 7%
PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:myc box dependent interacting protein 1;
PDBTitle: nmr structure of the tumor suppressor bin1: alternative2 splicing in melanoma and interaction with c-myc

Phyre2

PDB 2fic chain A

Region: 1021 - 1211
Aligned: 189
Modelled: 189
Confidence: 99.7%
Identity: 22%
PDB header:endocytosis/exocytosis, membrane protein
Chain: A: PDB Molecule:bridging integrator 1;
PDBTitle: the crystal structure of the bar domain from human bin1/amphiphysin ii2 and its implications for molecular recognition

Phyre2

PDB 1ng2 chain A domain 2

Region: 1502 - 1575
Aligned: 70
Modelled: 70
Confidence: 99.6%
Identity: 20%
Fold: SH3-like barrel
Superfamily: SH3-domain
Family: SH3-domain

Phyre2

PDB 2e5k chain A

Region: 1501 - 1577
Aligned: 77
Modelled: 77
Confidence: 99.6%
Identity: 17%
PDB header:protein binding
Chain: A: PDB Molecule:suppressor of t-cell receptor signaling 1;
PDBTitle: solution structure of sh3 domain in suppressor of t-cell2 receptor signaling 1

Phyre2

PDB 2rqr chain A

Region: 1480 - 1577
Aligned: 93
Modelled: 93
Confidence: 99.6%
Identity: 19%
PDB header:protein binding
Chain: A: PDB Molecule:engulfment and cell motility protein 1, linker, dedicator
PDBTitle: the solution structure of human dock2 sh3 domain - elmo1 peptide2 chimera complex

Phyre2

PDB 1uhc chain A

Region: 1504 - 1575
Aligned: 72
Modelled: 72
Confidence: 99.6%
Identity: 94%
Fold: SH3-like barrel
Superfamily: SH3-domain
Family: SH3-domain

Phyre2

PDB 3sog chain A

Region: 1020 - 1212
Aligned: 191
Modelled: 191
Confidence: 99.5%
Identity: 24%
PDB header:structural protein
Chain: A: PDB Molecule:amphiphysin;
PDBTitle: crystal structure of the bar domain of human amphiphysin, isoform 1

Phyre2

PDB 1uru chain A

Region: 1010 - 1209
Aligned: 198
Modelled: 196
Confidence: 99.5%
Identity: 23%
Fold: BAR/IMD domain-like
Superfamily: BAR/IMD domain-like
Family: BAR domain

Phyre2

PDB 1uru chain A

Region: 1010 - 1209
Aligned: 198
Modelled: 196
Confidence: 99.5%
Identity: 23%
PDB header:endocytosis
Chain: A: PDB Molecule:amphiphysin;
PDBTitle: amphiphysin bar domain from drosophila

Phyre2

100

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106

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109

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