Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP61889
DateThu Jan 5 12:07:26 GMT 2012
Unique Job IDfa4756fe15883e83

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c2pwzG_
Top template information
PDB header:oxidoreductase
Chain: G: PDB Molecule:malate dehydrogenase;
PDBTitle: crystal structure of the apo form of e.coli malate dehydrogenase
Confidence and coverage
Confidence:100.0% Coverage:100%
312 residues (100% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MKVAVLGAAGGIGQALALLLKTQLPSGSELSLYDIAPVTPGVAVDLSHIPTAVKIKGFSG
Secondary structure 

















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Disorder  ?



















???



































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   .........70.........80.........90.........100.........110.........120
Sequence  EDATPALEGADVVLISAGVARKPGMDRSDLFNVNAGIVKNLVQQVAKTCPKACIGIITNP
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Disorder 

















???????


































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   .........130.........140.........150.........160.........170.........180
Sequence  VNTTVAIAAEVLKKAGVYDKNKLFGVTTLDIIRSNTFVAELKGKQPGEVEVPVIGGHSGV
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   .........190.........200.........210.........220.........230.........240
Sequence  TILPLLSQVPGVSFTEQEVADLTKRIQNAGTEVVEAKAGGGSATLSMGQAAARFGLSLVR
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?



















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   .........250.........260.........270.........280.........290.........300
Sequence  ALQGEQGVVECAYVEGDGQYARFFSQPLLLGKNGVEERKSIGTLSAFEQNALEGMLDTLK
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   .........310..
Sequence  KDIALGEEFVNK
Secondary structure 

SS confidence 











Disorder 









??
Disorder confidence 











 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 2pwz chain G

3D model

Region: 1 - 312
Aligned: 312
Modelled: 312
Confidence: 100.0%
Identity: 100%
PDB header:oxidoreductase
Chain: G: PDB Molecule:malate dehydrogenase;
PDBTitle: crystal structure of the apo form of e.coli malate dehydrogenase

Phyre2

PDB 1mld chain A

3D model

Region: 2 - 312
Aligned: 309
Modelled: 311
Confidence: 100.0%
Identity: 59%
PDB header:oxidoreductase(nad(a)-choh(d))
Chain: A: PDB Molecule:malate dehydrogenase;
PDBTitle: refined structure of mitochondrial malate dehydrogenase2 from porcine heart and the consensus structure for3 dicarboxylic acid oxidoreductases

Phyre2

PDB 2dfd chain D

3D model

Region: 2 - 312
Aligned: 309
Modelled: 311
Confidence: 100.0%
Identity: 59%
PDB header:oxidoreductase
Chain: D: PDB Molecule:malate dehydrogenase;
PDBTitle: crystal structure of human malate dehydrogenase type 2

Phyre2

PDB 1sev chain A

3D model

Region: 1 - 311
Aligned: 309
Modelled: 311
Confidence: 100.0%
Identity: 54%
PDB header:oxidoreductase
Chain: A: PDB Molecule:malate dehydrogenase, glyoxysomal precursor;
PDBTitle: mature and translocatable forms of glyoxysomal malate2 dehydrogenase have different activities and stabilities3 but similar crystal structures

Phyre2

PDB 1smk chain D

3D model

Region: 1 - 311
Aligned: 309
Modelled: 311
Confidence: 100.0%
Identity: 54%
PDB header:oxidoreductase
Chain: D: PDB Molecule:malate dehydrogenase, glyoxysomal;
PDBTitle: mature and translocatable forms of glyoxysomal malate2 dehydrogenase have different activities and stabilities3 but similar crystal structures

Phyre2

PDB 7mdh chain A

3D model

Region: 1 - 312
Aligned: 305
Modelled: 312
Confidence: 100.0%
Identity: 24%
PDB header:chloroplastic malate dehydrogenase
Chain: A: PDB Molecule:protein (malate dehydrogenase);
PDBTitle: structural basis for light acitvation of a chloroplast enzyme. the2 structure of sorghum nadp-malate dehydrogenase in its oxidized form

Phyre2

PDB 5mdh chain B

3D model

Region: 1 - 311
Aligned: 303
Modelled: 311
Confidence: 100.0%
Identity: 23%
PDB header:oxidoreductase
Chain: B: PDB Molecule:malate dehydrogenase;
PDBTitle: crystal structure of ternary complex of porcine cytoplasmic malate2 dehydrogenase alpha-ketomalonate and tnad at 2.4 angstroms resolution

Phyre2

PDB 1b8v chain A

3D model

Region: 1 - 310
Aligned: 301
Modelled: 310
Confidence: 100.0%
Identity: 24%
PDB header:oxidoreductase
Chain: A: PDB Molecule:protein (malate dehydrogenase);
PDBTitle: malate dehydrogenase from aquaspirillum arcticum

Phyre2

PDB 1hyh chain A

3D model

Region: 2 - 310
Aligned: 291
Modelled: 306
Confidence: 100.0%
Identity: 20%
PDB header:oxidoreductase (choh(d)-nad+(a))
Chain: A: PDB Molecule:l-2-hydroxyisocaproate dehydrogenase;
PDBTitle: crystal structure of l-2-hydroxyisocaproate dehydrogenase from2 lactobacillus confusus at 2.2 angstroms resolution-an example of3 strong asymmetry between subunits

Phyre2

PDB 1ez4 chain B

3D model

Region: 1 - 312
Aligned: 297
Modelled: 312
Confidence: 100.0%
Identity: 24%
PDB header:oxidoreductase
Chain: B: PDB Molecule:lactate dehydrogenase;
PDBTitle: crystal structure of non-allosteric l-lactate dehydrogenase2 from lactobacillus pentosus at 2.3 angstrom resolution

Phyre2

PDB 1oju chain A

3D model

Region: 1 - 304
Aligned: 284
Modelled: 302
Confidence: 100.0%
Identity: 26%
PDB header:oxidoreductase
Chain: A: PDB Molecule:malate dehydrogenase;
PDBTitle: 2.8 a resolution structure of malate dehydrogenase from2 archaeoglobus fulgidus in complex with etheno-nad.

Phyre2

PDB 1hyg chain A

3D model

Region: 1 - 309
Aligned: 295
Modelled: 298
Confidence: 100.0%
Identity: 27%
PDB header:oxidoreductase
Chain: A: PDB Molecule:l-lactate/malate dehydrogenase;
PDBTitle: crystal structure of mj0490 gene product, the family of2 lactate/malate dehydrogenase

Phyre2

PDB 8ldh chain A

3D model

Region: 1 - 304
Aligned: 290
Modelled: 300
Confidence: 100.0%
Identity: 22%
PDB header:oxidoreductase(choh(d)-nad(a))
Chain: A: PDB Molecule:m4 apo-lactate dehydrogenase;
PDBTitle: refined crystal structure of dogfish m4 apo-lactate2 dehydrogenase

Phyre2

PDB 1lld chain A

3D model

Region: 2 - 305
Aligned: 290
Modelled: 304
Confidence: 100.0%
Identity: 27%
PDB header:oxidoreductase(choh (d)-nad (a))
Chain: A: PDB Molecule:l-lactate dehydrogenase;
PDBTitle: molecular basis of allosteric activation of bacterial l-lactate2 dehydrogenase

Phyre2

PDB 3nep chain X

3D model

Region: 1 - 312
Aligned: 292
Modelled: 312
Confidence: 100.0%
Identity: 27%
PDB header:oxidoreductase
Chain: X: PDB Molecule:malate dehydrogenase;
PDBTitle: 1.55a resolution structure of malate dehydrogenase from salinibacter2 ruber

Phyre2

PDB 3d0o chain A

3D model

Region: 2 - 304
Aligned: 289
Modelled: 303
Confidence: 100.0%
Identity: 25%
PDB header:oxidoreductase
Chain: A: PDB Molecule:l-lactate dehydrogenase 1;
PDBTitle: crystal structure of lactate dehydrogenase from2 staphylococcus aureus

Phyre2

PDB 1a5z chain A

3D model

Region: 1 - 307
Aligned: 292
Modelled: 300
Confidence: 100.0%
Identity: 28%
PDB header:oxidoreductase
Chain: A: PDB Molecule:l-lactate dehydrogenase;
PDBTitle: lactate dehydrogenase from thermotoga maritima (tmldh)

Phyre2

PDB 1wzi chain A

3D model

Region: 1 - 309
Aligned: 301
Modelled: 307
Confidence: 100.0%
Identity: 25%
PDB header:oxidoreductase
Chain: A: PDB Molecule:malate dehydrogenase;
PDBTitle: structural basis for alteration of cofactor specificity of2 malate dehydrogenase from thermus flavus

Phyre2

PDB 1y6j chain A

3D model

Region: 2 - 305
Aligned: 279
Modelled: 300
Confidence: 100.0%
Identity: 25%
PDB header:oxidoreductase
Chain: A: PDB Molecule:l-lactate dehydrogenase;
PDBTitle: l-lactate dehydrogenase from clostridium thermocellum cth-1135

Phyre2

PDB 2d4a chain C

3D model

Region: 3 - 311
Aligned: 287
Modelled: 309
Confidence: 100.0%
Identity: 23%
PDB header:oxidoreductase
Chain: C: PDB Molecule:malate dehydrogenase;
PDBTitle: structure of the malate dehydrogenase from aeropyrum pernix

Phyre2
1

c2pwzG_
2

c1mldA_
3

c2dfdD_
4

c1sevA_
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c1smkD_
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c7mdhA_
7

c5mdhB_
8

c1b8vA_
9

c1hyhA_
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c1ez4B_
11

c1ojuA_
12

c1hygA_
13

c8ldhA_
14

c1lldA_
15

c3nepX_
16

c3d0oA_
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c1a5zA_
18

c1wziA_
19

c1y6jA_
20

c2d4aC_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c2pwzG_



100.0 100 PDB header:oxidoreductase
Chain: G: PDB Molecule:malate dehydrogenase;
PDBTitle: crystal structure of the apo form of e.coli malate dehydrogenase
2c1mldA_



100.0 59 PDB header:oxidoreductase(nad(a)-choh(d))
Chain: A: PDB Molecule:malate dehydrogenase;
PDBTitle: refined structure of mitochondrial malate dehydrogenase2 from porcine heart and the consensus structure for3 dicarboxylic acid oxidoreductases
3c2dfdD_



100.0 59 PDB header:oxidoreductase
Chain: D: PDB Molecule:malate dehydrogenase;
PDBTitle: crystal structure of human malate dehydrogenase type 2
4c1sevA_



100.0 54 PDB header:oxidoreductase
Chain: A: PDB Molecule:malate dehydrogenase, glyoxysomal precursor;
PDBTitle: mature and translocatable forms of glyoxysomal malate2 dehydrogenase have different activities and stabilities3 but similar crystal structures
5c1smkD_



100.0 54 PDB header:oxidoreductase
Chain: D: PDB Molecule:malate dehydrogenase, glyoxysomal;
PDBTitle: mature and translocatable forms of glyoxysomal malate2 dehydrogenase have different activities and stabilities3 but similar crystal structures
6c7mdhA_



100.0 24 PDB header:chloroplastic malate dehydrogenase
Chain: A: PDB Molecule:protein (malate dehydrogenase);
PDBTitle: structural basis for light acitvation of a chloroplast enzyme. the2 structure of sorghum nadp-malate dehydrogenase in its oxidized form
7c5mdhB_



100.0 23 PDB header:oxidoreductase
Chain: B: PDB Molecule:malate dehydrogenase;
PDBTitle: crystal structure of ternary complex of porcine cytoplasmic malate2 dehydrogenase alpha-ketomalonate and tnad at 2.4 angstroms resolution
8c1b8vA_



100.0 24 PDB header:oxidoreductase
Chain: A: PDB Molecule:protein (malate dehydrogenase);
PDBTitle: malate dehydrogenase from aquaspirillum arcticum
9c1hyhA_



100.0 20 PDB header:oxidoreductase (choh(d)-nad+(a))
Chain: A: PDB Molecule:l-2-hydroxyisocaproate dehydrogenase;
PDBTitle: crystal structure of l-2-hydroxyisocaproate dehydrogenase from2 lactobacillus confusus at 2.2 angstroms resolution-an example of3 strong asymmetry between subunits
10c1ez4B_



100.0 24 PDB header:oxidoreductase
Chain: B: PDB Molecule:lactate dehydrogenase;
PDBTitle: crystal structure of non-allosteric l-lactate dehydrogenase2 from lactobacillus pentosus at 2.3 angstrom resolution
11c1ojuA_



100.0 26 PDB header:oxidoreductase
Chain: A: PDB Molecule:malate dehydrogenase;
PDBTitle: 2.8 a resolution structure of malate dehydrogenase from2 archaeoglobus fulgidus in complex with etheno-nad.
12c1hygA_



100.0 27 PDB header:oxidoreductase
Chain: A: PDB Molecule:l-lactate/malate dehydrogenase;
PDBTitle: crystal structure of mj0490 gene product, the family of2 lactate/malate dehydrogenase
13c8ldhA_



100.0 22 PDB header:oxidoreductase(choh(d)-nad(a))
Chain: A: PDB Molecule:m4 apo-lactate dehydrogenase;
PDBTitle: refined crystal structure of dogfish m4 apo-lactate2 dehydrogenase
14c1lldA_



100.0 27 PDB header:oxidoreductase(choh (d)-nad (a))
Chain: A: PDB Molecule:l-lactate dehydrogenase;
PDBTitle: molecular basis of allosteric activation of bacterial l-lactate2 dehydrogenase
15c3nepX_



100.0 27 PDB header:oxidoreductase
Chain: X: PDB Molecule:malate dehydrogenase;
PDBTitle: 1.55a resolution structure of malate dehydrogenase from salinibacter2 ruber
16c3d0oA_



100.0 25 PDB header:oxidoreductase
Chain: A: PDB Molecule:l-lactate dehydrogenase 1;
PDBTitle: crystal structure of lactate dehydrogenase from2 staphylococcus aureus
17c1a5zA_



100.0 28 PDB header:oxidoreductase
Chain: A: PDB Molecule:l-lactate dehydrogenase;
PDBTitle: lactate dehydrogenase from thermotoga maritima (tmldh)
18c1wziA_



100.0 25 PDB header:oxidoreductase
Chain: A: PDB Molecule:malate dehydrogenase;
PDBTitle: structural basis for alteration of cofactor specificity of2 malate dehydrogenase from thermus flavus
19c1y6jA_



100.0 25 PDB header:oxidoreductase
Chain: A: PDB Molecule:l-lactate dehydrogenase;
PDBTitle: l-lactate dehydrogenase from clostridium thermocellum cth-1135
20c2d4aC_



100.0 23 PDB header:oxidoreductase
Chain: C: PDB Molecule:malate dehydrogenase;
PDBTitle: structure of the malate dehydrogenase from aeropyrum pernix
21c1pzfD_



not modelled 100.0 28 PDB header:oxidoreductase
Chain: D: PDB Molecule:lactate dehydrogenase;
PDBTitle: t.gondii ldh1 ternary complex with apad+ and oxalate
22c2ldxA_



not modelled 100.0 25 PDB header:oxidoreductase(choh(d)-nad(a))
Chain: A: PDB Molecule:apo-lactate dehydrogenase;
PDBTitle: characterization of the antigenic sites on the refined 3-2 angstroms resolution structure of mouse testicular lactate3 dehydrogenase c4
23c2e37B_



not modelled 100.0 28 PDB header:oxidoreductase
Chain: B: PDB Molecule:l-lactate dehydrogenase;
PDBTitle: structure of tt0471 protein from thermus thermophilus
24c3dl2A_



not modelled 100.0 23 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:ubiquitin-conjugating enzyme e2 variant 3;
PDBTitle: hexagonal structure of the ldh domain of human ubiquitin-2 conjugating enzyme e2-like isoform a
25c3p7mC_



not modelled 100.0 28 PDB header:oxidoreductase
Chain: C: PDB Molecule:malate dehydrogenase;
PDBTitle: structure of putative lactate dehydrogenase from francisella2 tularensis subsp. tularensis schu s4
26c1ur5C_



not modelled 100.0 27 PDB header:oxidoreductase
Chain: C: PDB Molecule:malate dehydrogenase;
PDBTitle: stabilization of a tetrameric malate dehydrogenase by2 introduction of a disulfide bridge at the dimer/dimer3 interface
27c1gv1D_



not modelled 100.0 26 PDB header:oxidoreductase
Chain: D: PDB Molecule:malate dehydrogenase;
PDBTitle: structural basis for thermophilic protein stability:2 structures of thermophilic and mesophilic malate3 dehydrogenases
28c3gviB_



not modelled 100.0 27 PDB header:oxidoreductase
Chain: B: PDB Molecule:malate dehydrogenase;
PDBTitle: crystal structure of lactate/malate dehydrogenase from2 brucella melitensis in complex with adp
29c1u4sA_



not modelled 100.0 28 PDB header:oxidoreductase
Chain: A: PDB Molecule:l-lactate dehydrogenase;
PDBTitle: plasmodium falciparum lactate dehydrogenase complexed with 2,6-2 naphthalenedisulphonic acid
30c1ldbA_



not modelled 100.0 24 PDB header:oxidoreductase(choh(d)-nad(a))
Chain: A: PDB Molecule:apo-l-lactate dehydrogenase;
PDBTitle: structure determination and refinement of bacillus2 stearothermophilus lactate dehydrogenase
31c3pqeD_



not modelled 100.0 25 PDB header:oxidoreductase
Chain: D: PDB Molecule:l-lactate dehydrogenase;
PDBTitle: crystal structure of l-lactate dehydrogenase from bacillus subtilis2 with h171c mutation
32c2v65A_



not modelled 100.0 25 PDB header:oxidoreductase
Chain: A: PDB Molecule:l-lactate dehydrogenase a chain;
PDBTitle: apo ldh from the psychrophile c. gunnari
33c2hjrK_



not modelled 100.0 32 PDB header:oxidoreductase
Chain: K: PDB Molecule:malate dehydrogenase;
PDBTitle: crystal structure of cryptosporidium parvum malate2 dehydrogenase
34c2fnzA_



not modelled 100.0 29 PDB header:oxidoreductase
Chain: A: PDB Molecule:lactate dehydrogenase;
PDBTitle: crystal structure of the lactate dehydrogenase from cryptosporidium2 parvum complexed with cofactor (b-nicotinamide adenine dinucleotide)3 and inhibitor (oxamic acid)
35c2v6bB_



not modelled 100.0 26 PDB header:oxidoreductase
Chain: B: PDB Molecule:l-lactate dehydrogenase;
PDBTitle: crystal structure of lactate dehydrogenase from deinococcus2 radiodurans (apo form)
36c3fi9B_



not modelled 100.0 23 PDB header:oxidoreductase
Chain: B: PDB Molecule:malate dehydrogenase;
PDBTitle: crystal structure of malate dehydrogenase from porphyromonas2 gingivalis
37c3tl2A_



not modelled 100.0 30 PDB header:oxidoreductase
Chain: A: PDB Molecule:malate dehydrogenase;
PDBTitle: crystal structure of bacillus anthracis str. ames malate dehydrogenase2 in closed conformation.
38c1llcA_



not modelled 100.0 25 PDB header:oxidoreductase(choh(d)-nad(a))
Chain: A: PDB Molecule:l-lactate dehydrogenase;
PDBTitle: structure determination of the allosteric l-lactate dehydrogenase from2 lactobacillus casei at 3.0 angstroms resolution
39c2hlpB_



not modelled 100.0 27 PDB header:oxidoreductase
Chain: B: PDB Molecule:malate dehydrogenase;
PDBTitle: crystal structure of the e267r mutant of a halophilic2 malate dehydrogenase in the apo form
40c3fefB_



not modelled 100.0 19 PDB header:hydrolase
Chain: B: PDB Molecule:putative glucosidase lpld;
PDBTitle: crystal structure of putative glucosidase lpld from2 bacillus subtilis
41c1s6yA_



not modelled 100.0 19 PDB header:hydrolase
Chain: A: PDB Molecule:6-phospho-beta-glucosidase;
PDBTitle: 2.3a crystal structure of phospho-beta-glucosidase
42c1up6F_



not modelled 100.0 18 PDB header:hydrolase
Chain: F: PDB Molecule:6-phospho-beta-glucosidase;
PDBTitle: structure of the 6-phospho-beta glucosidase from thermotoga2 maritima at 2.55 angstrom resolution in the tetragonal form3 with manganese, nad+ and glucose-6-phosphate
43d2cmda2



not modelled 100.0 99 Fold:LDH C-terminal domain-like
Superfamily:LDH C-terminal domain-like
Family:Lactate & malate dehydrogenases, C-terminal domain
44d1mlda2



not modelled 100.0 53 Fold:LDH C-terminal domain-like
Superfamily:LDH C-terminal domain-like
Family:Lactate & malate dehydrogenases, C-terminal domain
45c1u8xX_



not modelled 100.0 17 PDB header:hydrolase
Chain: X: PDB Molecule:maltose-6'-phosphate glucosidase;
PDBTitle: crystal structure of glva from bacillus subtilis, a metal-requiring,2 nad-dependent 6-phospho-alpha-glucosidase
46d1ez4a2



not modelled 100.0 22 Fold:LDH C-terminal domain-like
Superfamily:LDH C-terminal domain-like
Family:Lactate & malate dehydrogenases, C-terminal domain
47d1pzga2



not modelled 100.0 23 Fold:LDH C-terminal domain-like
Superfamily:LDH C-terminal domain-like
Family:Lactate & malate dehydrogenases, C-terminal domain
48d1civa2



not modelled 100.0 22 Fold:LDH C-terminal domain-like
Superfamily:LDH C-terminal domain-like
Family:Lactate & malate dehydrogenases, C-terminal domain
49d5mdha2



not modelled 100.0 18 Fold:LDH C-terminal domain-like
Superfamily:LDH C-terminal domain-like
Family:Lactate & malate dehydrogenases, C-terminal domain
50d1a5za2



not modelled 100.0 25 Fold:LDH C-terminal domain-like
Superfamily:LDH C-terminal domain-like
Family:Lactate & malate dehydrogenases, C-terminal domain
51d1o6za2



not modelled 100.0 25 Fold:LDH C-terminal domain-like
Superfamily:LDH C-terminal domain-like
Family:Lactate & malate dehydrogenases, C-terminal domain
52d1ldna2



not modelled 100.0 21 Fold:LDH C-terminal domain-like
Superfamily:LDH C-terminal domain-like
Family:Lactate & malate dehydrogenases, C-terminal domain
53d1gv0a2



not modelled 100.0 28 Fold:LDH C-terminal domain-like
Superfamily:LDH C-terminal domain-like
Family:Lactate & malate dehydrogenases, C-terminal domain
54d1oc4a2



not modelled 100.0 24 Fold:LDH C-terminal domain-like
Superfamily:LDH C-terminal domain-like
Family:Lactate & malate dehydrogenases, C-terminal domain
55d5mdha1



not modelled 100.0 27 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
56d7mdha2



not modelled 100.0 22 Fold:LDH C-terminal domain-like
Superfamily:LDH C-terminal domain-like
Family:Lactate & malate dehydrogenases, C-terminal domain
57d1hyha2



not modelled 100.0 19 Fold:LDH C-terminal domain-like
Superfamily:LDH C-terminal domain-like
Family:Lactate & malate dehydrogenases, C-terminal domain
58d1b8pa1



not modelled 100.0 29 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
59d1o6za1



not modelled 100.0 28 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
60d1llda2



not modelled 100.0 21 Fold:LDH C-terminal domain-like
Superfamily:LDH C-terminal domain-like
Family:Lactate & malate dehydrogenases, C-terminal domain
61d7mdha1



not modelled 100.0 26 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
62d9ldta2



not modelled 100.0 24 Fold:LDH C-terminal domain-like
Superfamily:LDH C-terminal domain-like
Family:Lactate & malate dehydrogenases, C-terminal domain
63d1i0za2



not modelled 100.0 23 Fold:LDH C-terminal domain-like
Superfamily:LDH C-terminal domain-like
Family:Lactate & malate dehydrogenases, C-terminal domain
64d1y7ta2



not modelled 100.0 19 Fold:LDH C-terminal domain-like
Superfamily:LDH C-terminal domain-like
Family:Lactate & malate dehydrogenases, C-terminal domain
65d1t2da2



not modelled 100.0 23 Fold:LDH C-terminal domain-like
Superfamily:LDH C-terminal domain-like
Family:Lactate & malate dehydrogenases, C-terminal domain
66d2cmda1



not modelled 100.0 99 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
67d1guza2



not modelled 100.0 26 Fold:LDH C-terminal domain-like
Superfamily:LDH C-terminal domain-like
Family:Lactate & malate dehydrogenases, C-terminal domain
68d1uxja2



not modelled 100.0 25 Fold:LDH C-terminal domain-like
Superfamily:LDH C-terminal domain-like
Family:Lactate & malate dehydrogenases, C-terminal domain
69d1y6ja2



not modelled 100.0 22 Fold:LDH C-terminal domain-like
Superfamily:LDH C-terminal domain-like
Family:Lactate & malate dehydrogenases, C-terminal domain
70d1y7ta1



not modelled 100.0 30 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
71c1obbB_



not modelled 100.0 18 PDB header:hydrolase
Chain: B: PDB Molecule:alpha-glucosidase;
PDBTitle: alpha-glucosidase a, agla, from thermotoga maritima in2 complex with maltose and nad+
72d1ldma2



not modelled 100.0 20 Fold:LDH C-terminal domain-like
Superfamily:LDH C-terminal domain-like
Family:Lactate & malate dehydrogenases, C-terminal domain
73d1i10a2



not modelled 100.0 24 Fold:LDH C-terminal domain-like
Superfamily:LDH C-terminal domain-like
Family:Lactate & malate dehydrogenases, C-terminal domain
74d1civa1



not modelled 100.0 27 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
75d2ldxa2



not modelled 100.0 24 Fold:LDH C-terminal domain-like
Superfamily:LDH C-terminal domain-like
Family:Lactate & malate dehydrogenases, C-terminal domain
76d1b8pa2



not modelled 100.0 21 Fold:LDH C-terminal domain-like
Superfamily:LDH C-terminal domain-like
Family:Lactate & malate dehydrogenases, C-terminal domain
77d1i0za1



not modelled 100.0 24 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
78d1ojua2



not modelled 100.0 21 Fold:LDH C-terminal domain-like
Superfamily:LDH C-terminal domain-like
Family:Lactate & malate dehydrogenases, C-terminal domain
79d1ldma1



not modelled 100.0 24 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
80d1llca2



not modelled 100.0 22 Fold:LDH C-terminal domain-like
Superfamily:LDH C-terminal domain-like
Family:Lactate & malate dehydrogenases, C-terminal domain
81d1i10a1



not modelled 100.0 27 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
82d1hyea2



not modelled 100.0 21 Fold:LDH C-terminal domain-like
Superfamily:LDH C-terminal domain-like
Family:Lactate & malate dehydrogenases, C-terminal domain
83d5ldha1



not modelled 100.0 25 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
84d2ldxa1



not modelled 100.0 27 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
85d9ldta1



not modelled 100.0 24 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
86d1llda1



not modelled 100.0 31 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
87d1u8xx1



not modelled 100.0 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
88d1ojua1



not modelled 100.0 33 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
89d1a5za1



not modelled 100.0 33 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
90d1s6ya1



not modelled 100.0 22 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
91d1ldna1



not modelled 100.0 26 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
92d1up7a1



not modelled 99.9 23 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
93d1guza1



not modelled 99.9 31 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
94d1obba1



not modelled 99.9 23 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
95d1hyha1



not modelled 99.9 20 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
96d1t2da1



not modelled 99.9 34 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
97c1vjtA_



not modelled 99.9 19 PDB header:hydrolase
Chain: A: PDB Molecule:alpha-glucosidase;
PDBTitle: crystal structure of alpha-glucosidase (tm0752) from thermotoga2 maritima at 2.50 a resolution
98d1mlda1



not modelled 99.9 63 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
99d1pzga1



not modelled 99.9 34 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
100d1llca1



not modelled 99.9 28 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
101d1hyea1



not modelled 99.9 34 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
102d1gv0a1



not modelled 99.9 29 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
103d1y6ja1



not modelled 99.9 28 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
104d1ez4a1



not modelled 99.9 26 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
105d1uxja1



not modelled 99.8 28 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
106d1vjta1



not modelled 99.6 17 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
107d1mv8a2



not modelled 98.7 15 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
108c2o3jC_



not modelled 98.7 17 PDB header:oxidoreductase
Chain: C: PDB Molecule:udp-glucose 6-dehydrogenase;
PDBTitle: structure of caenorhabditis elegans udp-glucose dehydrogenase
109c3gg2B_



not modelled 98.6 15 PDB header:oxidoreductase
Chain: B: PDB Molecule:sugar dehydrogenase, udp-glucose/gdp-mannose
PDBTitle: crystal structure of udp-glucose 6-dehydrogenase from2 porphyromonas gingivalis bound to product udp-glucuronate
110c3plnA_



not modelled 98.5 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:udp-glucose 6-dehydrogenase;
PDBTitle: crystal structure of klebsiella pneumoniae udp-glucose 6-dehydrogenase2 complexed with udp-glucose
111d1dlja2



not modelled 98.5 22 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
112c1mv8A_



not modelled 98.4 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:gdp-mannose 6-dehydrogenase;
PDBTitle: 1.55 a crystal structure of a ternary complex of gdp-mannose2 dehydrogenase from psuedomonas aeruginosa
113c3prjB_



not modelled 98.4 14 PDB header:oxidoreductase
Chain: B: PDB Molecule:udp-glucose 6-dehydrogenase;
PDBTitle: role of packing defects in the evolution of allostery and induced fit2 in human udp-glucose dehydrogenase.
114d1txga2



not modelled 98.4 25 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
115d1s6ya2



not modelled 98.4 19 Fold:LDH C-terminal domain-like
Superfamily:LDH C-terminal domain-like
Family:AglA-like glucosidase
116c2y0dB_



not modelled 98.4 17 PDB header:oxidoreductase
Chain: B: PDB Molecule:udp-glucose dehydrogenase;
PDBTitle: bcec mutation y10k
117d1up7a2



not modelled 98.3 18 Fold:LDH C-terminal domain-like
Superfamily:LDH C-terminal domain-like
Family:AglA-like glucosidase
118c3g79A_



not modelled 98.3 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:ndp-n-acetyl-d-galactosaminuronic acid dehydrogenase;
PDBTitle: crystal structure of ndp-n-acetyl-d-galactosaminuronic acid2 dehydrogenase from methanosarcina mazei go1
119c2q3eH_



not modelled 98.3 14 PDB header:oxidoreductase
Chain: H: PDB Molecule:udp-glucose 6-dehydrogenase;
PDBTitle: structure of human udp-glucose dehydrogenase complexed with nadh and2 udp-glucose
120d1n1ea2



not modelled 98.2 17 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0