PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c8ldhA_

Fold library id	PDB Header	Molecule	Title
c8ldhA_	PDB header: oxidoreductase(choh(d)-nad(a))	Chain: A: PDB Molecule: m4 apo-lactate dehydrogenase;	PDBTitle: refined crystal structure of dogfish m4 apo-lactate2 dehydrogenase

Links to external resources
Added to library: Tue Mar 16 13:44:37 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence A T L K D K L I G H L A T S Q E P R S Y N K I T V V G V G A V G M A C A I S I L M K D L A D E V A L V D V M E D K L K G E M M D L Q H G S L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
S S
S T T T
S
S
T G G

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence F L H T A K I V S G K D Y S V S A G S K L V V I T A G A R Q Q E G E S R L N L V Q R N V N I F K F I I P N I V K H S P D C I I L V V S N P V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) G
S S G G G G T T
S
T T
T T
S S S

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence D V L T Y V A W K L S G L P M H R I I G S G C N L D S A R F R Y L M G E R L G V H S C S C H G W V I G E H G D S V P S V W S G M N V A S I K

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
G G G
T T T S
T T T
B S S S T T
T T

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280

Sequence L H P L D G T N K D K Q D W K K L H K D V V D S A Y E V I K L K G Y T S W A I G L S V A D L A E T I M K N L C R V H P V S T M V K D F Y G I

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S S
S S S S S S T S S
T T
T T S S S

. . . . . . . . . 290 . . . . . . . . . 300 . . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . .

Sequence K D N V F L S L P C V L N D H G I S N I V K M K L K P N E E Q Q L Q K S A T T L W D I Q K D L K F

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S
T T
S

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	A	T	L	K	D	K	L	I	G	H	L	A	T	S	Q	E	P	R	S	Y	N	K	I	T	V	V	G	V	G	A	V	G	M	A	C	A	I	S	I	L	M	K	D	L	A	D	E	V	A	L	V	D	V	M	E	D	K	L	K	G	E	M	M	D	L	Q	H	G	S	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)												S								S	S								S												T	T	T			S							S															T	G	G
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	F	L	H	T	A	K	I	V	S	G	K	D	Y	S	V	S	A	G	S	K	L	V	V	I	T	A	G	A	R	Q	Q	E	G	E	S	R	L	N	L	V	Q	R	N	V	N	I	F	K	F	I	I	P	N	I	V	K	H	S	P	D	C	I	I	L	V	V	S	N	P	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	G										S	S	G	G	G	G	T	T		S												T	T																										T	T							S	S	S
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	D	V	L	T	Y	V	A	W	K	L	S	G	L	P	M	H	R	I	I	G	S	G	C	N	L	D	S	A	R	F	R	Y	L	M	G	E	R	L	G	V	H	S	C	S	C	H	G	W	V	I	G	E	H	G	D	S	V	P	S	V	W	S	G	M	N	V	A	S	I	K
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)												T			G	G	G					T	T																T	S		T	T	T							B	S	S	S	T	T											T	T
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280
Sequence	L	H	P	L	D	G	T	N	K	D	K	Q	D	W	K	K	L	H	K	D	V	V	D	S	A	Y	E	V	I	K	L	K	G	Y	T	S	W	A	I	G	L	S	V	A	D	L	A	E	T	I	M	K	N	L	C	R	V	H	P	V	S	T	M	V	K	D	F	Y	G	I
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)					S	S			S	S	S	S	S	S	T																		S	S																		T	T												T	T	S	S	S
	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.
Sequence	K	D	N	V	F	L	S	L	P	C	V	L	N	D	H	G	I	S	N	I	V	K	M	K	L	K	P	N	E	E	Q	Q	L	Q	K	S	A	T	T	L	W	D	I	Q	K	D	L	K	F
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		S	S											T	T																																S