Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	P	R	F	A	A	N	L	S	M	M	F	T	E	V	P	F	I	E	R	F	A	A	A	R	K	A	G	F	D	A	V	E	F	L	F	P	Y	N	Y	S	T	L	Q	I	Q	K	Q	L	E	Q	N	H	L	T	L	A	L	F	N
Secondary structure
SS confidence
Disorder		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		T	A	P	G	D	I	N	A	G	E	W	G	L	S	A	L	P	G	R	E	H	E	A	H	A	D	I	D	L	A	L	E	Y	A	L	A	L	N	C	E	Q	V	H	V	M	A	G	V	V	P	A	G	E	D	A	E	R	Y	R	A
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		V	F	I	D	N	I	R	Y	A	A	D	R	F	A	P	H	G	K	R	I	L	V	E	A	L	S	P	G	V	K	P	H	Y	L	F	S	S	Q	Y	Q	A	L	A	I	V	E	E	V	A	R	D	N	V	F	I	Q	L	D	T	F
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		H	A	Q	K	V	D	G	N	L	T	H	L	I	R	D	Y	A	G	K	Y	A	H	V	Q	I	A	G	L	P	D	R	H	E	P	D	D	G	E	I	N	Y	P	W	L	F	R	L	F	D	E	V	G	Y	Q	G	W	I	G	C	E
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.
Sequence		Y	K	P	R	G	L	T	E	E	G	L	G	W	F	D	A	W	R
Secondary structure
SS confidence
Disorder																	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1k77 chain A Region: 2 - 258 Aligned: 257 Modelled: 257 Confidence: 100.0% Identity: 99% Fold: TIM beta/alpha-barrel Superfamily: Xylose isomerase-like Family: Hypothetical protein YgbM (EC1530) Phyre2 PDB 3ngf chain A Region: 1 - 258 Aligned: 257 Modelled: 258 Confidence: 100.0% Identity: 54% PDB header:isomerase Chain: A: PDB Molecule:ap endonuclease, family 2; PDBTitle: crystal structure of ap endonuclease, family 2 from brucella2 melitensis Phyre2 PDB 1i60 chain A Region: 2 - 257 Aligned: 246 Modelled: 255 Confidence: 100.0% Identity: 21% Fold: TIM beta/alpha-barrel Superfamily: Xylose isomerase-like Family: IolI-like Phyre2 PDB 3kws chain B Region: 1 - 257 Aligned: 249 Modelled: 255 Confidence: 100.0% Identity: 16% PDB header:isomerase Chain: B: PDB Molecule:putative sugar isomerase; PDBTitle: crystal structure of putative sugar isomerase (yp_001305149.1) from2 parabacteroides distasonis atcc 8503 at 1.68 a resolution Phyre2 PDB 2hk1 chain D Region: 2 - 255 Aligned: 247 Modelled: 251 Confidence: 100.0% Identity: 18% PDB header:isomerase Chain: D: PDB Molecule:d-psicose 3-epimerase; PDBTitle: crystal structure of d-psicose 3-epimerase (dpease) in the presence of2 d-fructose Phyre2 PDB 3ju2 chain A Region: 1 - 258 Aligned: 250 Modelled: 258 Confidence: 100.0% Identity: 19% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein smc04130; PDBTitle: crystal structure of protein smc04130 from sinorhizobium meliloti 1021 Phyre2 PDB 2zvr chain A Region: 1 - 256 Aligned: 249 Modelled: 252 Confidence: 100.0% Identity: 17% PDB header:isomerase Chain: A: PDB Molecule:uncharacterized protein tm_0416; PDBTitle: crystal structure of a d-tagatose 3-epimerase-related2 protein from thermotoga maritima Phyre2 PDB 2zds chain B Region: 4 - 256 Aligned: 247 Modelled: 253 Confidence: 100.0% Identity: 23% PDB header:dna binding protein Chain: B: PDB Molecule:putative dna-binding protein; PDBTitle: crystal structure of sco6571 from streptomyces coelicolor2 a3(2) Phyre2 PDB 3qxb chain B Region: 3 - 256 Aligned: 253 Modelled: 254 Confidence: 100.0% Identity: 14% PDB header:isomerase Chain: B: PDB Molecule:putative xylose isomerase; PDBTitle: crystal structure of a putative xylose isomerase (yp_426450.1) from2 rhodospirillum rubrum atcc 11170 at 1.90 a resolution Phyre2 PDB 3cny chain A Region: 3 - 257 Aligned: 239 Modelled: 245 Confidence: 100.0% Identity: 14% PDB header:biosynthetic protein Chain: A: PDB Molecule:inositol catabolism protein iole; PDBTitle: crystal structure of a putative inositol catabolism protein iole2 (iole, lp_3607) from lactobacillus plantarum wcfs1 at 1.85 a3 resolution Phyre2 PDB 3ktc chain B Region: 2 - 252 Aligned: 249 Modelled: 251 Confidence: 100.0% Identity: 16% PDB header:isomerase Chain: B: PDB Molecule:xylose isomerase; PDBTitle: crystal structure of putative sugar isomerase (yp_050048.1) from2 erwinia carotovora atroseptica scri1043 at 1.54 a resolution Phyre2 PDB 2qw5 chain B Region: 16 - 256 Aligned: 236 Modelled: 241 Confidence: 100.0% Identity: 15% PDB header:isomerase Chain: B: PDB Molecule:xylose isomerase-like tim barrel; PDBTitle: crystal structure of a putative sugar phosphate isomerase/epimerase2 (ava4194) from anabaena variabilis atcc 29413 at 1.78 a resolution Phyre2 PDB 3dx5 chain A Region: 2 - 258 Aligned: 240 Modelled: 242 Confidence: 100.0% Identity: 16% PDB header:lyase Chain: A: PDB Molecule:uncharacterized protein asbf; PDBTitle: crystal structure of the probable 3-dhs dehydratase asbf involved in2 the petrobactin synthesis from bacillus anthracis Phyre2 PDB 2ou4 chain C Region: 2 - 258 Aligned: 249 Modelled: 252 Confidence: 100.0% Identity: 19% PDB header:isomerase Chain: C: PDB Molecule:d-tagatose 3-epimerase; PDBTitle: crystal structure of d-tagatose 3-epimerase from2 pseudomonas cichorii Phyre2 PDB 2g0w chain A domain 1 Region: 4 - 257 Aligned: 232 Modelled: 244 Confidence: 100.0% Identity: 15% Fold: TIM beta/alpha-barrel Superfamily: Xylose isomerase-like Family: IolI-like Phyre2 PDB 3cqk chain B Region: 3 - 256 Aligned: 246 Modelled: 254 Confidence: 100.0% Identity: 14% PDB header:isomerase Chain: B: PDB Molecule:l-ribulose-5-phosphate 3-epimerase ulae; PDBTitle: crystal structure of l-xylulose-5-phosphate 3-epimerase ulae (form b)2 complex with zn2+ and sulfate Phyre2 PDB 3l23 chain A Region: 2 - 256 Aligned: 249 Modelled: 255 Confidence: 100.0% Identity: 9% PDB header:isomerase Chain: A: PDB Molecule:sugar phosphate isomerase/epimerase; PDBTitle: crystal structure of sugar phosphate isomerase/epimerase2 (yp_001303399.1) from parabacteroides distasonis atcc 8503 at 1.70 a3 resolution Phyre2 PDB 3obe chain B Region: 3 - 256 Aligned: 240 Modelled: 253 Confidence: 100.0% Identity: 15% PDB header:isomerase Chain: B: PDB Molecule:sugar phosphate isomerase/epimerase; PDBTitle: crystal structure of a sugar phosphate isomerase/epimerase (bdi_3400)2 from parabacteroides distasonis atcc 8503 at 1.70 a resolution Phyre2 PDB 2q02 chain A domain 1 Region: 2 - 256 Aligned: 236 Modelled: 252 Confidence: 100.0% Identity: 16% Fold: TIM beta/alpha-barrel Superfamily: Xylose isomerase-like Family: IolI-like Phyre2 PDB 3lmz chain A Region: 3 - 256 Aligned: 217 Modelled: 218 Confidence: 100.0% Identity: 16% PDB header:isomerase Chain: A: PDB Molecule:putative sugar isomerase; PDBTitle: crystal structure of putative sugar isomerase. (yp_001305105.1) from2 parabacteroides distasonis atcc 8503 at 1.44 a resolution Phyre2 1 d1k77a_ 2 c3ngfA_ 3 d1i60a_ 4 c3kwsB_ 5 c2hk1D_ 6 c3ju2A_ 7 c2zvrA_ 8 c2zdsB_ 9 c3qxbB_ 10 c3cnyA_ 11 c3ktcB_ 12 c2qw5B_ 13 c3dx5A_ 14 c2ou4C_ 15 d2g0wa1 16 c3cqkB_ 17 c3l23A_ 18 c3obeB_ 19 d2q02a1 20 c3lmzA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1k77a_ 100.0 99 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:Hypothetical protein YgbM (EC1530) 2 c3ngfA_ 100.0 54 PDB header:isomerase Chain: A: PDB Molecule:ap endonuclease, family 2; PDBTitle: crystal structure of ap endonuclease, family 2 from brucella2 melitensis 3 d1i60a_ 100.0 21 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:IolI-like 4 c3kwsB_ 100.0 16 PDB header:isomerase Chain: B: PDB Molecule:putative sugar isomerase; PDBTitle: crystal structure of putative sugar isomerase (yp_001305149.1) from2 parabacteroides distasonis atcc 8503 at 1.68 a resolution 5 c2hk1D_ 100.0 18 PDB header:isomerase Chain: D: PDB Molecule:d-psicose 3-epimerase; PDBTitle: crystal structure of d-psicose 3-epimerase (dpease) in the presence of2 d-fructose 6 c3ju2A_ 100.0 19 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein smc04130; PDBTitle: crystal structure of protein smc04130 from sinorhizobium meliloti 1021 7 c2zvrA_ 100.0 17 PDB header:isomerase Chain: A: PDB Molecule:uncharacterized protein tm_0416; PDBTitle: crystal structure of a d-tagatose 3-epimerase-related2 protein from thermotoga maritima 8 c2zdsB_ 100.0 23 PDB header:dna binding protein Chain: B: PDB Molecule:putative dna-binding protein; PDBTitle: crystal structure of sco6571 from streptomyces coelicolor2 a3(2) 9 c3qxbB_ 100.0 14 PDB header:isomerase Chain: B: PDB Molecule:putative xylose isomerase; PDBTitle: crystal structure of a putative xylose isomerase (yp_426450.1) from2 rhodospirillum rubrum atcc 11170 at 1.90 a resolution 10 c3cnyA_ 100.0 14 PDB header:biosynthetic protein Chain: A: PDB Molecule:inositol catabolism protein iole; PDBTitle: crystal structure of a putative inositol catabolism protein iole2 (iole, lp_3607) from lactobacillus plantarum wcfs1 at 1.85 a3 resolution 11 c3ktcB_ 100.0 16 PDB header:isomerase Chain: B: PDB Molecule:xylose isomerase; PDBTitle: crystal structure of putative sugar isomerase (yp_050048.1) from2 erwinia carotovora atroseptica scri1043 at 1.54 a resolution 12 c2qw5B_ 100.0 15 PDB header:isomerase Chain: B: PDB Molecule:xylose isomerase-like tim barrel; PDBTitle: crystal structure of a putative sugar phosphate isomerase/epimerase2 (ava4194) from anabaena variabilis atcc 29413 at 1.78 a resolution 13 c3dx5A_ 100.0 16 PDB header:lyase Chain: A: PDB Molecule:uncharacterized protein asbf; PDBTitle: crystal structure of the probable 3-dhs dehydratase asbf involved in2 the petrobactin synthesis from bacillus anthracis 14 c2ou4C_ 100.0 19 PDB header:isomerase Chain: C: PDB Molecule:d-tagatose 3-epimerase; PDBTitle: crystal structure of d-tagatose 3-epimerase from2 pseudomonas cichorii 15 d2g0wa1 100.0 15 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:IolI-like 16 c3cqkB_ 100.0 14 PDB header:isomerase Chain: B: PDB Molecule:l-ribulose-5-phosphate 3-epimerase ulae; PDBTitle: crystal structure of l-xylulose-5-phosphate 3-epimerase ulae (form b)2 complex with zn2+ and sulfate 17 c3l23A_ 100.0 9 PDB header:isomerase Chain: A: PDB Molecule:sugar phosphate isomerase/epimerase; PDBTitle: crystal structure of sugar phosphate isomerase/epimerase2 (yp_001303399.1) from parabacteroides distasonis atcc 8503 at 1.70 a3 resolution 18 c3obeB_ 100.0 15 PDB header:isomerase Chain: B: PDB Molecule:sugar phosphate isomerase/epimerase; PDBTitle: crystal structure of a sugar phosphate isomerase/epimerase (bdi_3400)2 from parabacteroides distasonis atcc 8503 at 1.70 a resolution 19 d2q02a1 100.0 16 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:IolI-like 20 c3lmzA_ 100.0 16 PDB header:isomerase Chain: A: PDB Molecule:putative sugar isomerase; PDBTitle: crystal structure of putative sugar isomerase. (yp_001305105.1) from2 parabacteroides distasonis atcc 8503 at 1.44 a resolution 21 d1qtwa_ not modelled 100.0 16 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:Endonuclease IV 22 c3p6lA_ not modelled 100.0 13 PDB header:isomerase Chain: A: PDB Molecule:sugar phosphate isomerase/epimerase; PDBTitle: crystal structure of a sugar phosphate isomerase/epimerase (bdi_1903)2 from parabacteroides distasonis atcc 8503 at 1.85 a resolution 23 d1xp3a1 not modelled 100.0 14 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:Endonuclease IV 24 d1muwa_ not modelled 100.0 19 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:Xylose isomerase 25 d1qt1a_ not modelled 100.0 17 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:Xylose isomerase 26 d1bxca_ not modelled 100.0 18 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:Xylose isomerase 27 d2glka1 not modelled 100.0 19 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:Xylose isomerase 28 d1bxba_ not modelled 100.0 18 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:Xylose isomerase 29 d1yx1a1 not modelled 100.0 13 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:KguE-like 30 c2x7vA_ not modelled 100.0 14 PDB header:hydrolase Chain: A: PDB Molecule:probable endonuclease 4; PDBTitle: crystal structure of thermotoga maritima endonuclease iv in2 the presence of zinc 31 d1tz9a_ not modelled 100.0 16 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:UxuA-like 32 d1xima_ not modelled 100.0 20 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:Xylose isomerase 33 c3aamA_ not modelled 100.0 19 PDB header:hydrolase Chain: A: PDB Molecule:endonuclease iv; PDBTitle: crystal structure of endonuclease iv from thermus thermophilus hb8 34 c3bdkB_ not modelled 100.0 11 PDB header:lyase Chain: B: PDB Molecule:d-mannonate dehydratase; PDBTitle: crystal structure of streptococcus suis mannonate2 dehydratase complexed with substrate analogue 35 d1xlma_ not modelled 99.9 19 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:Xylose isomerase 36 c2i56A_ not modelled 99.8 11 PDB header:isomerase, metal-binding protein Chain: A: PDB Molecule:l-rhamnose isomerase; PDBTitle: crystal structure of l-rhamnose isomerase from pseudomonas2 stutzeri with l-rhamnose 37 d1a0ea_ not modelled 99.8 16 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:Xylose isomerase 38 d1a0da_ not modelled 99.7 16 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:Xylose isomerase 39 d1a0ca_ not modelled 99.7 16 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:Xylose isomerase 40 c3bzjA_ not modelled 99.6 14 PDB header:hydrolase Chain: A: PDB Molecule:uv endonuclease; PDBTitle: uvde k229l 41 c3bwwA_ not modelled 98.8 15 PDB header:metal binding protein Chain: A: PDB Molecule:protein of unknown function duf692/cog3220; PDBTitle: crystal structure of a duf692 family protein (hs_1138) from2 haemophilus somnus 129pt at 2.20 a resolution 42 c1sr9A_ not modelled 97.7 13 PDB header:transferase Chain: A: PDB Molecule:2-isopropylmalate synthase; PDBTitle: crystal structure of leua from mycobacterium tuberculosis 43 d1d8wa_ not modelled 97.6 11 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:L-rhamnose isomerase 44 c3p14C_ not modelled 97.6 12 PDB header:isomerase Chain: C: PDB Molecule:l-rhamnose isomerase; PDBTitle: crystal structure of l-rhamnose isomerase with a novel high thermo-2 stability from bacillus halodurans 45 c3ivuB_ not modelled 97.4 12 PDB header:transferase Chain: B: PDB Molecule:homocitrate synthase, mitochondrial; PDBTitle: homocitrate synthase lys4 bound to 2-og 46 c2ftpA_ not modelled 97.2 13 PDB header:lyase Chain: A: PDB Molecule:hydroxymethylglutaryl-coa lyase; PDBTitle: crystal structure of hydroxymethylglutaryl-coa lyase from pseudomonas2 aeruginosa 47 c3ewbX_ not modelled 97.0 12 PDB header:transferase Chain: X: PDB Molecule:2-isopropylmalate synthase; PDBTitle: crystal structure of n-terminal domain of putative 2-2 isopropylmalate synthase from listeria monocytogenes 48 d1nvma2 not modelled 96.8 13 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:HMGL-like 49 c3bleA_ not modelled 96.8 10 PDB header:transferase Chain: A: PDB Molecule:citramalate synthase from leptospira interrogans; PDBTitle: crystal structure of the catalytic domain of licms in2 complexed with malonate 50 c1rr2A_ not modelled 96.8 11 PDB header:transferase Chain: A: PDB Molecule:transcarboxylase 5s subunit; PDBTitle: propionibacterium shermanii transcarboxylase 5s subunit bound to 2-2 ketobutyric acid 51 c1ydnA_ not modelled 96.5 14 PDB header:lyase Chain: A: PDB Molecule:hydroxymethylglutaryl-coa lyase; PDBTitle: crystal structure of the hmg-coa lyase from brucella melitensis,2 northeast structural genomics target lr35. 52 c2zyfA_ not modelled 96.3 13 PDB header:transferase Chain: A: PDB Molecule:homocitrate synthase; PDBTitle: crystal structure of homocitrate synthase from thermus thermophilus2 complexed with magnesuim ion and alpha-ketoglutarate 53 c2nx9B_ not modelled 96.3 12 PDB header:lyase Chain: B: PDB Molecule:oxaloacetate decarboxylase 2, subunit alpha; PDBTitle: crystal structure of the carboxyltransferase domain of the2 oxaloacetate decarboxylase na+ pump from vibrio cholerae 54 c3hpxB_ not modelled 96.3 13 PDB header:transferase Chain: B: PDB Molecule:2-isopropylmalate synthase; PDBTitle: crystal structure of mycobacterium tuberculosis leua active site2 domain 1-425 (truncation mutant delta:426-644) 55 c1ydoC_ not modelled 95.9 8 PDB header:lyase Chain: C: PDB Molecule:hmg-coa lyase; PDBTitle: crystal structure of the bacillis subtilis hmg-coa lyase, northeast2 structural genomics target sr181. 56 c2xioA_ not modelled 95.6 8 PDB header:hydrolase Chain: A: PDB Molecule:putative deoxyribonuclease tatdn1; PDBTitle: structure of putative deoxyribonuclease tatdn1 isoform a 57 c1nvmG_ not modelled 95.5 14 PDB header:lyase/oxidoreductase Chain: G: PDB Molecule:4-hydroxy-2-oxovalerate aldolase; PDBTitle: crystal structure of a bifunctional aldolase-dehydrogenase :2 sequestering a reactive and volatile intermediate 58 c3eegB_ not modelled 95.3 14 PDB header:transferase Chain: B: PDB Molecule:2-isopropylmalate synthase; PDBTitle: crystal structure of a 2-isopropylmalate synthase from2 cytophaga hutchinsonii 59 c3bg3B_ not modelled 94.3 11 PDB header:ligase Chain: B: PDB Molecule:pyruvate carboxylase, mitochondrial; PDBTitle: crystal structure of human pyruvate carboxylase (missing2 the biotin carboxylase domain at the n-terminus) 60 c2cw6B_ not modelled 93.7 11 PDB header:lyase Chain: B: PDB Molecule:hydroxymethylglutaryl-coa lyase, mitochondrial; PDBTitle: crystal structure of human hmg-coa lyase: insights into2 catalysis and the molecular basis for3 hydroxymethylglutaric aciduria 61 c2zq0B_ not modelled 93.3 14 PDB header:hydrolase Chain: B: PDB Molecule:alpha-glucosidase (alpha-glucosidase susb); PDBTitle: crystal structure of susb complexed with acarbose 62 c1xc6A_ not modelled 93.0 9 PDB header:hydrolase Chain: A: PDB Molecule:beta-galactosidase; PDBTitle: native structure of beta-galactosidase from penicillium sp. in complex2 with galactose 63 c3a24A_ not modelled 92.6 11 PDB header:hydrolase Chain: A: PDB Molecule:alpha-galactosidase; PDBTitle: crystal structure of bt1871 retaining glycosidase 64 c1uz4A_ not modelled 92.6 10 PDB header:hydrolase Chain: A: PDB Molecule:man5a; PDBTitle: common inhibition of beta-glucosidase and beta-mannosidase2 by isofagomine lactam reflects different conformational3 intineraries for glucoside and mannoside hydrolysis 65 d1uuqa_ not modelled 92.6 10 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:beta-glycanases 66 d1sr9a2 not modelled 92.5 8 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:HMGL-like 67 c3noyA_ not modelled 91.3 13 PDB header:oxidoreductase Chain: A: PDB Molecule:4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; PDBTitle: crystal structure of ispg (gcpe) 68 c2p10D_ not modelled 89.7 11 PDB header:hydrolase Chain: D: PDB Molecule:mll9387 protein; PDBTitle: crystal structure of a putative phosphonopyruvate hydrolase (mll9387)2 from mesorhizobium loti maff303099 at 2.15 a resolution 69 c3gk0H_ not modelled 88.1 20 PDB header:transferase Chain: H: PDB Molecule:pyridoxine 5'-phosphate synthase; PDBTitle: crystal structure of pyridoxal phosphate biosynthetic2 protein from burkholderia pseudomallei 70 c2vg2C_ not modelled 87.7 19 PDB header:transferase Chain: C: PDB Molecule:undecaprenyl pyrophosphate synthetase; PDBTitle: rv2361 with ipp 71 d1tg7a5 not modelled 87.4 10 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:Glycosyl hydrolases family 35 catalytic domain 72 c3d3aA_ not modelled 86.6 9 PDB header:hydrolase Chain: A: PDB Molecule:beta-galactosidase; PDBTitle: crystal structure of a beta-galactosidase from bacteroides2 thetaiotaomicron 73 c3l55B_ not modelled 86.5 17 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:b-1,4-endoglucanase/cellulase; PDBTitle: crystal structure of a putative beta-1,4-endoglucanase /2 cellulase from prevotella bryantii 74 d1h1na_ not modelled 85.6 9 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:beta-glycanases 75 d1edga_ not modelled 85.2 12 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:beta-glycanases 76 d1rh9a1 not modelled 85.1 10 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:beta-glycanases 77 c3ogrA_ not modelled 84.8 12 PDB header:hydrolase Chain: A: PDB Molecule:beta-galactosidase; PDBTitle: complex structure of beta-galactosidase from trichoderma reesei with2 galactose 78 c2h90A_ not modelled 84.4 19 PDB header:oxidoreductase Chain: A: PDB Molecule:xenobiotic reductase a; PDBTitle: xenobiotic reductase a in complex with coumarin 79 d1qwga_ not modelled 83.4 18 Fold:TIM beta/alpha-barrel Superfamily:(2r)-phospho-3-sulfolactate synthase ComA Family:(2r)-phospho-3-sulfolactate synthase ComA 80 c2dh3A_ not modelled 83.4 9 PDB header:transport protein, signaling protein Chain: A: PDB Molecule:4f2 cell-surface antigen heavy chain; PDBTitle: crystal structure of human ed-4f2hc 81 d1h1ya_ not modelled 83.0 15 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:D-ribulose-5-phosphate 3-epimerase 82 c3pzqA_ not modelled 82.7 12 PDB header:hydrolase Chain: A: PDB Molecule:mannan endo-1,4-beta-mannosidase. glycosyl hydrolase family PDBTitle: structure of the hyperthermostable endo-1,4-beta-d-mannanase from2 thermotoga petrophila rku-1 with maltose and glycerol 83 d1z41a1 not modelled 82.4 23 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 84 c3thaB_ not modelled 82.1 14 PDB header:lyase Chain: B: PDB Molecule:tryptophan synthase alpha chain; PDBTitle: tryptophan synthase subunit alpha from campylobacter jejuni. 85 c3hf3A_ not modelled 82.1 21 PDB header:oxidoreductase Chain: A: PDB Molecule:chromate reductase; PDBTitle: old yellow enzyme from thermus scotoductus sa-01 86 c2yfnA_ not modelled 81.8 11 PDB header:hydrolase Chain: A: PDB Molecule:alpha-galactosidase-sucrose kinase agask; PDBTitle: galactosidase domain of alpha-galactosidase-sucrose kinase,2 agask 87 c2epoB_ not modelled 81.2 11 PDB header:hydrolase Chain: B: PDB Molecule:n-acetyl-beta-d-glucosaminidase; PDBTitle: n-acetyl-b-d-glucosaminidase (gcna) from streptococcus gordonii 88 d1vyra_ not modelled 79.7 21 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 89 c3f4cA_ not modelled 79.4 14 PDB header:hydrolase Chain: A: PDB Molecule:organophosphorus hydrolase; PDBTitle: crystal structure of organophosphorus hydrolase from geobacillus2 stearothermophilus strain 10, with glycerol bound 90 d1qopa_ not modelled 79.3 13 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 91 d2c0ha1 not modelled 79.3 12 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:beta-glycanases 92 c3civA_ not modelled 79.0 11 PDB header:hydrolase Chain: A: PDB Molecule:endo-beta-1,4-mannanase; PDBTitle: crystal structure of the endo-beta-1,4-mannanase from2 alicyclobacillus acidocaldarius 93 c2y8kA_ not modelled 78.4 9 PDB header:hydrolase Chain: A: PDB Molecule:carbohydrate binding family 6; PDBTitle: structure of ctgh5-cbm6, an arabinoxylan-specific xylanase. 94 d1ujpa_ not modelled 78.3 10 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 95 c3jugA_ not modelled 78.0 10 PDB header:hydrolase Chain: A: PDB Molecule:beta-mannanase; PDBTitle: crystal structure of endo-beta-1,4-mannanase from the alkaliphilic2 bacillus sp. n16-5 96 d1j6oa_ not modelled 77.9 6 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:TatD Mg-dependent DNase-like 97 c3ipwA_ not modelled 76.2 8 PDB header:hydrolase Chain: A: PDB Molecule:hydrolase tatd family protein; PDBTitle: crystal structure of hydrolase tatd family protein from entamoeba2 histolytica 98 d1wkya2 not modelled 75.2 8 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:beta-glycanases 99 c3thdD_ not modelled 74.8 16 PDB header:hydrolase Chain: D: PDB Molecule:beta-galactosidase; PDBTitle: crystal structure of human beta-galactosidase in complex with 1-2 deoxygalactonojirimycin 100 d1m5wa_ not modelled 74.6 17 Fold:TIM beta/alpha-barrel Superfamily:Pyridoxine 5'-phosphate synthase Family:Pyridoxine 5'-phosphate synthase 101 c3k2gA_ not modelled 74.5 13 PDB header:resiniferatoxin binding protein Chain: A: PDB Molecule:resiniferatoxin-binding, phosphotriesterase- PDBTitle: crystal structure of a resiniferatoxin-binding protein from2 rhodobacter sphaeroides 102 d1gwja_ not modelled 73.9 17 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 103 d1i4na_ not modelled 73.7 10 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 104 c3dxiB_ not modelled 73.6 10 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative aldolase; PDBTitle: crystal structure of the n-terminal domain of a putative2 aldolase (bvu_2661) from bacteroides vulgatus 105 c1wkyA_ not modelled 73.5 10 PDB header:hydrolase Chain: A: PDB Molecule:endo-beta-1,4-mannanase; PDBTitle: crystal structure of alkaline mannanase from bacillus sp. strain jamb-2 602: catalytic domain and its carbohydrate binding module 106 d1rqba2 not modelled 73.4 9 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:HMGL-like 107 c3gkaB_ not modelled 72.5 23 PDB header:oxidoreductase Chain: B: PDB Molecule:n-ethylmaleimide reductase; PDBTitle: crystal structure of n-ethylmaleimidine reductase from2 burkholderia pseudomallei 108 c2xn1B_ not modelled 72.2 15 PDB header:hydrolase Chain: B: PDB Molecule:alpha-galactosidase; PDBTitle: structure of alpha-galactosidase from lactobacillus acidophilus ncfm2 with tris 109 d1x7fa2 not modelled 71.5 15 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:Outer surface protein, N-terminal domain 110 c3ncoA_ not modelled 71.2 8 PDB header:hydrolase Chain: A: PDB Molecule:endoglucanase fncel5a; PDBTitle: crystal structure of fncel5a from f. nodosum rt17-b1 111 c3b0vD_ not modelled 70.6 13 PDB header:oxidoreductase/rna Chain: D: PDB Molecule:trna-dihydrouridine synthase; PDBTitle: trna-dihydrouridine synthase from thermus thermophilus in complex with2 trna 112 c2gq8A_ not modelled 70.5 15 PDB header:oxidoreductase Chain: A: PDB Molecule:oxidoreductase, fmn-binding; PDBTitle: structure of sye1, an oye homologue from s. ondeidensis, in complex2 with p-hydroxyacetophenone 113 d2je8a5 not modelled 70.4 11 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:beta-glycanases 114 c3stgA_ not modelled 69.6 9 PDB header:transferase Chain: A: PDB Molecule:2-dehydro-3-deoxyphosphooctonate aldolase; PDBTitle: crystal structure of a58p, del(n59), and loop 7 truncated mutant of 3-2 deoxy-d-manno-octulosonate 8-phosphate synthase (kdo8ps) from3 neisseria meningitidis 115 d1o60a_ not modelled 69.5 10 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I DAHP synthetase 116 c3mi6A_ not modelled 69.5 16 PDB header:hydrolase Chain: A: PDB Molecule:alpha-galactosidase; PDBTitle: crystal structure of the alpha-galactosidase from lactobacillus2 brevis, northeast structural genomics consortium target lbr11. 117 d1j5ta_ not modelled 69.5 13 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 118 c3iwpK_ not modelled 69.1 12 PDB header:metal binding protein Chain: K: PDB Molecule:copper homeostasis protein cutc homolog; PDBTitle: crystal structure of human copper homeostasis protein cutc 119 c1u83A_ not modelled 69.0 15 PDB header:lyase Chain: A: PDB Molecule:phosphosulfolactate synthase; PDBTitle: psl synthase from bacillus subtilis 120 d1u83a_ not modelled 69.0 15 Fold:TIM beta/alpha-barrel Superfamily:(2r)-phospho-3-sulfolactate synthase ComA Family:(2r)-phospho-3-sulfolactate synthase ComA

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0