Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	E	L	Y	L	D	T	S	D	V	V	A	V	K	A	L	S	R	I	F	P	L	A	G	V	T	T	N	P	S	I	I	A	A	G	K	K	P	L	D	V	V	L	P	Q	L	H	E	A	M	G	G	Q	G	R	L	F	A	Q	V
Secondary structure
SS confidence
Disorder		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		M	A	T	T	A	E	G	M	V	N	D	A	L	K	L	R	S	I	I	A	D	I	V	V	K	V	P	V	T	A	E	G	L	A	A	I	K	M	L	K	A	E	G	I	P	T	L	G	T	A	V	Y	G	A	A	Q	G	L	L	S
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		A	L	A	G	A	E	Y	V	A	P	Y	V	N	R	I	D	A	Q	G	G	S	G	I	Q	T	V	T	D	L	H	Q	L	L	K	M	H	A	P	Q	A	K	V	L	A	A	S	F	K	T	P	R	Q	A	L	D	C	L	L	A	G
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220
Sequence		C	E	S	I	T	L	P	L	D	V	A	Q	Q	M	I	S	Y	P	A	V	D	A	A	V	A	K	F	E	Q	D	W	Q	G	A	F	G	R	T	S	I
Secondary structure
SS confidence
Disorder																																			?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1l6w chain A Region: 1 - 220 Aligned: 220 Modelled: 220 Confidence: 100.0% Identity: 100% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: Class I aldolase Phyre2 PDB 3s1v chain D Region: 1 - 219 Aligned: 217 Modelled: 219 Confidence: 100.0% Identity: 31% PDB header:transferase Chain: D: PDB Molecule:probable transaldolase; PDBTitle: transaldolase from thermoplasma acidophilum in complex with d-fructose2 6-phosphate schiff-base intermediate Phyre2 PDB 1vpx chain A Region: 1 - 217 Aligned: 204 Modelled: 217 Confidence: 100.0% Identity: 31% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: Class I aldolase Phyre2 PDB 1wx0 chain A domain 1 Region: 1 - 204 Aligned: 202 Modelled: 204 Confidence: 100.0% Identity: 36% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: Class I aldolase Phyre2 PDB 1onr chain A Region: 2 - 214 Aligned: 205 Modelled: 213 Confidence: 100.0% Identity: 31% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: Class I aldolase Phyre2 PDB 3cq0 chain B Region: 2 - 214 Aligned: 205 Modelled: 213 Confidence: 100.0% Identity: 29% PDB header:transferase Chain: B: PDB Molecule:putative transaldolase ygr043c; PDBTitle: crystal structure of tal2_yeast Phyre2 PDB 1f05 chain A Region: 2 - 214 Aligned: 205 Modelled: 213 Confidence: 100.0% Identity: 30% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: Class I aldolase Phyre2 PDB 3m16 chain A Region: 2 - 214 Aligned: 207 Modelled: 213 Confidence: 100.0% Identity: 32% PDB header:transferase Chain: A: PDB Molecule:transaldolase; PDBTitle: structure of a transaldolase from oleispira antarctica Phyre2 PDB 2e1d chain A domain 1 Region: 2 - 214 Aligned: 207 Modelled: 213 Confidence: 100.0% Identity: 30% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: Class I aldolase Phyre2 PDB 3igx chain A Region: 2 - 214 Aligned: 205 Modelled: 212 Confidence: 100.0% Identity: 29% PDB header:transferase Chain: A: PDB Molecule:transaldolase; PDBTitle: 1.85 angstrom resolution crystal structure of transaldolase b (tala)2 from francisella tularensis. Phyre2 PDB 3hjz chain A Region: 2 - 214 Aligned: 207 Modelled: 213 Confidence: 100.0% Identity: 28% PDB header:transferase Chain: A: PDB Molecule:transaldolase b; PDBTitle: the structure of an aldolase from prochlorococcus marinus Phyre2 PDB 3clm chain A Region: 2 - 214 Aligned: 210 Modelled: 213 Confidence: 100.0% Identity: 30% PDB header:lyase Chain: A: PDB Molecule:transaldolase; PDBTitle: crystal structure of transaldolase (yp_208650.1) from neisseria2 gonorrhoeae fa 1090 at 1.14 a resolution Phyre2 PDB 1xm3 chain A Region: 62 - 192 Aligned: 127 Modelled: 131 Confidence: 97.9% Identity: 22% Fold: TIM beta/alpha-barrel Superfamily: ThiG-like Family: ThiG-like Phyre2 PDB 1kbi chain B Region: 93 - 214 Aligned: 122 Modelled: 122 Confidence: 97.8% Identity: 16% PDB header:oxidoreductase Chain: B: PDB Molecule:cytochrome b2; PDBTitle: crystallographic study of the recombinant flavin-binding domain of2 baker's yeast flavocytochrome b2: comparison with the intact wild-3 type enzyme Phyre2 PDB 1kbi chain A domain 1 Region: 93 - 214 Aligned: 122 Modelled: 122 Confidence: 97.8% Identity: 16% Fold: TIM beta/alpha-barrel Superfamily: FMN-linked oxidoreductases Family: FMN-linked oxidoreductases Phyre2 PDB 1ea0 chain A domain 2 Region: 63 - 194 Aligned: 111 Modelled: 111 Confidence: 97.7% Identity: 25% Fold: TIM beta/alpha-barrel Superfamily: FMN-linked oxidoreductases Family: FMN-linked oxidoreductases Phyre2 PDB 2htm chain B Region: 46 - 220 Aligned: 172 Modelled: 175 Confidence: 97.7% Identity: 23% PDB header:biosynthetic protein Chain: B: PDB Molecule:thiazole biosynthesis protein thig; PDBTitle: crystal structure of ttha0676 from thermus thermophilus hb8 Phyre2 PDB 3ffs chain C Region: 87 - 214 Aligned: 125 Modelled: 128 Confidence: 97.7% Identity: 12% PDB header:oxidoreductase Chain: C: PDB Molecule:inosine-5-monophosphate dehydrogenase; PDBTitle: the crystal structure of cryptosporidium parvum inosine-5'-2 monophosphate dehydrogenase Phyre2 PDB 1tb3 chain A domain 1 Region: 93 - 214 Aligned: 119 Modelled: 119 Confidence: 97.4% Identity: 12% Fold: TIM beta/alpha-barrel Superfamily: FMN-linked oxidoreductases Family: FMN-linked oxidoreductases Phyre2 PDB 1zfj chain A Region: 51 - 187 Aligned: 136 Modelled: 134 Confidence: 97.4% Identity: 17% PDB header:oxidoreductase Chain: A: PDB Molecule:inosine monophosphate dehydrogenase; PDBTitle: inosine monophosphate dehydrogenase (impdh; ec 1.1.1.205) from2 streptococcus pyogenes Phyre2 1 d1l6wa_ 2 c3s1vD_ 3 d1vpxa_ 4 d1wx0a1 5 d1onra_ 6 c3cq0B_ 7 d1f05a_ 8 c3m16A_ 9 d2e1da1 10 c3igxA_ 11 c3hjzA_ 12 c3clmA_ 13 d1xm3a_ 14 c1kbiB_ 15 d1kbia1 16 d1ea0a2 17 c2htmB_ 18 c3ffsC_ 19 d1tb3a1 20 c1zfjA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1l6wa_ 100.0 100 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 2 c3s1vD_ 100.0 31 PDB header:transferase Chain: D: PDB Molecule:probable transaldolase; PDBTitle: transaldolase from thermoplasma acidophilum in complex with d-fructose2 6-phosphate schiff-base intermediate 3 d1vpxa_ 100.0 31 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 4 d1wx0a1 100.0 36 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 5 d1onra_ 100.0 31 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 6 c3cq0B_ 100.0 29 PDB header:transferase Chain: B: PDB Molecule:putative transaldolase ygr043c; PDBTitle: crystal structure of tal2_yeast 7 d1f05a_ 100.0 30 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 8 c3m16A_ 100.0 32 PDB header:transferase Chain: A: PDB Molecule:transaldolase; PDBTitle: structure of a transaldolase from oleispira antarctica 9 d2e1da1 100.0 30 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 10 c3igxA_ 100.0 29 PDB header:transferase Chain: A: PDB Molecule:transaldolase; PDBTitle: 1.85 angstrom resolution crystal structure of transaldolase b (tala)2 from francisella tularensis. 11 c3hjzA_ 100.0 28 PDB header:transferase Chain: A: PDB Molecule:transaldolase b; PDBTitle: the structure of an aldolase from prochlorococcus marinus 12 c3clmA_ 100.0 30 PDB header:lyase Chain: A: PDB Molecule:transaldolase; PDBTitle: crystal structure of transaldolase (yp_208650.1) from neisseria2 gonorrhoeae fa 1090 at 1.14 a resolution 13 d1xm3a_ 97.9 22 Fold:TIM beta/alpha-barrel Superfamily:ThiG-like Family:ThiG-like 14 c1kbiB_ 97.8 16 PDB header:oxidoreductase Chain: B: PDB Molecule:cytochrome b2; PDBTitle: crystallographic study of the recombinant flavin-binding domain of2 baker's yeast flavocytochrome b2: comparison with the intact wild-3 type enzyme 15 d1kbia1 97.8 16 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 16 d1ea0a2 97.7 25 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 17 c2htmB_ 97.7 23 PDB header:biosynthetic protein Chain: B: PDB Molecule:thiazole biosynthesis protein thig; PDBTitle: crystal structure of ttha0676 from thermus thermophilus hb8 18 c3ffsC_ 97.7 12 PDB header:oxidoreductase Chain: C: PDB Molecule:inosine-5-monophosphate dehydrogenase; PDBTitle: the crystal structure of cryptosporidium parvum inosine-5'-2 monophosphate dehydrogenase 19 d1tb3a1 97.4 12 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 20 c1zfjA_ 97.4 17 PDB header:oxidoreductase Chain: A: PDB Molecule:inosine monophosphate dehydrogenase; PDBTitle: inosine monophosphate dehydrogenase (impdh; ec 1.1.1.205) from2 streptococcus pyogenes 21 d1goxa_ not modelled 97.3 16 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 22 d1eepa_ not modelled 97.3 14 Fold:TIM beta/alpha-barrel Superfamily:Inosine monophosphate dehydrogenase (IMPDH) Family:Inosine monophosphate dehydrogenase (IMPDH) 23 d1ofda2 not modelled 97.3 25 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 24 d1p0ka_ not modelled 97.3 12 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 25 c2a7nA_ not modelled 97.1 16 PDB header:oxidoreductase Chain: A: PDB Molecule:l(+)-mandelate dehydrogenase; PDBTitle: crystal structure of the g81a mutant of the active chimera of (s)-2 mandelate dehydrogenase 26 c3q58A_ not modelled 97.1 15 PDB header:isomerase Chain: A: PDB Molecule:n-acetylmannosamine-6-phosphate 2-epimerase; PDBTitle: structure of n-acetylmannosamine-6-phosphate epimerase from salmonella2 enterica 27 c3qc3B_ not modelled 97.1 13 PDB header:isomerase Chain: B: PDB Molecule:d-ribulose-5-phosphate-3-epimerase; PDBTitle: crystal structure of a d-ribulose-5-phosphate-3-epimerase (np_954699)2 from homo sapiens at 2.20 a resolution 28 d1vrda1 not modelled 97.0 16 Fold:TIM beta/alpha-barrel Superfamily:Inosine monophosphate dehydrogenase (IMPDH) Family:Inosine monophosphate dehydrogenase (IMPDH) 29 d1wa3a1 not modelled 97.0 13 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 30 d1p4ca_ not modelled 96.9 19 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 31 c2e77B_ not modelled 96.9 12 PDB header:oxidoreductase Chain: B: PDB Molecule:lactate oxidase; PDBTitle: crystal structure of l-lactate oxidase with pyruvate complex 32 c2vdcF_ not modelled 96.9 23 PDB header:oxidoreductase Chain: F: PDB Molecule:glutamate synthase [nadph] large chain; PDBTitle: the 9.5 a resolution structure of glutamate synthase from2 cryo-electron microscopy and its oligomerization behavior3 in solution: functional implications. 33 c3labA_ not modelled 96.8 19 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative kdpg (2-keto-3-deoxy-6-phosphogluconate) PDBTitle: crystal structure of a putative kdpg (2-keto-3-deoxy-6-2 phosphogluconate) aldolase from oleispira antarctica 34 c2yw3E_ not modelled 96.8 19 PDB header:lyase Chain: E: PDB Molecule:4-hydroxy-2-oxoglutarate aldolase/2-deydro-3- PDBTitle: crystal structure analysis of the 4-hydroxy-2-oxoglutarate aldolase/2-2 deydro-3-deoxyphosphogluconate aldolase from tthb1 35 c2v82A_ not modelled 96.8 16 PDB header:lyase Chain: A: PDB Molecule:2-dehydro-3-deoxy-6-phosphogalactonate aldolase; PDBTitle: kdpgal complexed to kdpgal 36 c1vrdA_ not modelled 96.8 18 PDB header:oxidoreductase Chain: A: PDB Molecule:inosine-5'-monophosphate dehydrogenase; PDBTitle: crystal structure of inosine-5'-monophosphate dehydrogenase (tm1347)2 from thermotoga maritima at 2.18 a resolution 37 d1wv2a_ not modelled 96.8 18 Fold:TIM beta/alpha-barrel Superfamily:ThiG-like Family:ThiG-like 38 d2flia1 not modelled 96.7 13 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:D-ribulose-5-phosphate 3-epimerase 39 d1zfja1 not modelled 96.7 17 Fold:TIM beta/alpha-barrel Superfamily:Inosine monophosphate dehydrogenase (IMPDH) Family:Inosine monophosphate dehydrogenase (IMPDH) 40 c3igsB_ not modelled 96.6 15 PDB header:isomerase Chain: B: PDB Molecule:n-acetylmannosamine-6-phosphate 2-epimerase 2; PDBTitle: structure of the salmonella enterica n-acetylmannosamine-6-phosphate2 2-epimerase 41 c1lm1A_ not modelled 96.6 23 PDB header:oxidoreductase Chain: A: PDB Molecule:ferredoxin-dependent glutamate synthase; PDBTitle: structural studies on the synchronization of catalytic centers in2 glutamate synthase: native enzyme 42 c1me9A_ not modelled 96.6 14 PDB header:oxidoreductase Chain: A: PDB Molecule:inosine-5'-monophosphate dehydrogenase; PDBTitle: inosine monophosphate dehydrogenase (impdh) from2 tritrichomonas foetus with imp bound 43 d1wbha1 not modelled 96.5 16 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 44 c2cdh1_ not modelled 96.4 15 PDB header:transferase Chain: 1: PDB Molecule:enoyl reductase; PDBTitle: architecture of the thermomyces lanuginosus fungal fatty2 acid synthase at 5 angstrom resolution. 45 c2rduA_ not modelled 96.4 11 PDB header:oxidoreductase Chain: A: PDB Molecule:hydroxyacid oxidase 1; PDBTitle: crystal structure of human glycolate oxidase in complex with2 glyoxylate 46 c1jcnA_ not modelled 96.2 17 PDB header:oxidoreductase Chain: A: PDB Molecule:inosine monophosphate dehydrogenase i; PDBTitle: binary complex of human type-i inosine monophosphate dehydrogenase2 with 6-cl-imp 47 c2p10D_ not modelled 96.1 15 PDB header:hydrolase Chain: D: PDB Molecule:mll9387 protein; PDBTitle: crystal structure of a putative phosphonopyruvate hydrolase (mll9387)2 from mesorhizobium loti maff303099 at 2.15 a resolution 48 c2jbmA_ not modelled 96.1 14 PDB header:transferase Chain: A: PDB Molecule:nicotinate-nucleotide pyrophosphorylase; PDBTitle: qprtase structure from human 49 d1xi3a_ not modelled 96.1 17 Fold:TIM beta/alpha-barrel Superfamily:Thiamin phosphate synthase Family:Thiamin phosphate synthase 50 c3inpA_ not modelled 96.1 11 PDB header:isomerase Chain: A: PDB Molecule:d-ribulose-phosphate 3-epimerase; PDBTitle: 2.05 angstrom resolution crystal structure of d-ribulose-phosphate 3-2 epimerase from francisella tularensis. 51 d1o4ua1 not modelled 96.0 15 Fold:TIM beta/alpha-barrel Superfamily:Nicotinate/Quinolinate PRTase C-terminal domain-like Family:NadC C-terminal domain-like 52 d1rd5a_ not modelled 96.0 17 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 53 c3pajA_ not modelled 95.9 19 PDB header:transferase Chain: A: PDB Molecule:nicotinate-nucleotide pyrophosphorylase, carboxylating; PDBTitle: 2.00 angstrom resolution crystal structure of a quinolinate2 phosphoribosyltransferase from vibrio cholerae o1 biovar eltor str.3 n16961 54 c2b7pA_ not modelled 95.9 14 PDB header:transferase Chain: A: PDB Molecule:probable nicotinate-nucleotide pyrophosphorylase; PDBTitle: crystal structure of quinolinic acid phosphoribosyltransferase from2 helicobacter pylori 55 c3bo9B_ not modelled 95.9 15 PDB header:oxidoreductase Chain: B: PDB Molecule:putative nitroalkan dioxygenase; PDBTitle: crystal structure of putative nitroalkan dioxygenase (tm0800) from2 thermotoga maritima at 2.71 a resolution 56 c3khjE_ not modelled 95.9 13 PDB header:oxidoreductase Chain: E: PDB Molecule:inosine-5-monophosphate dehydrogenase; PDBTitle: c. parvum inosine monophosphate dehydrogenase bound by inhibitor c64 57 c2c3zA_ not modelled 95.7 9 PDB header:lyase Chain: A: PDB Molecule:indole-3-glycerol phosphate synthase; PDBTitle: crystal structure of a truncated variant of indole-3-2 glycerol phosphate synthase from sulfolobus solfataricus 58 d1y0ea_ not modelled 95.7 7 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:NanE-like 59 c1x1oC_ not modelled 95.7 13 PDB header:transferase Chain: C: PDB Molecule:nicotinate-nucleotide pyrophosphorylase; PDBTitle: crystal structure of project id tt0268 from thermus thermophilus hb8 60 c1o4uA_ not modelled 95.6 15 PDB header:transferase Chain: A: PDB Molecule:type ii quinolic acid phosphoribosyltransferase; PDBTitle: crystal structure of a nicotinate nucleotide pyrophosphorylase2 (tm1645) from thermotoga maritima at 2.50 a resolution 61 d1vhca_ not modelled 95.6 17 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 62 d1yxya1 not modelled 95.5 17 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:NanE-like 63 d1vc4a_ not modelled 95.5 20 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 64 d1juba_ not modelled 95.5 11 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 65 c3r2gA_ not modelled 95.5 16 PDB header:oxidoreductase Chain: A: PDB Molecule:inosine 5'-monophosphate dehydrogenase; PDBTitle: crystal structure of inosine 5' monophosphate dehydrogenase from2 legionella pneumophila 66 d1jr1a1 not modelled 95.3 19 Fold:TIM beta/alpha-barrel Superfamily:Inosine monophosphate dehydrogenase (IMPDH) Family:Inosine monophosphate dehydrogenase (IMPDH) 67 c3bw2A_ not modelled 95.3 25 PDB header:oxidoreductase Chain: A: PDB Molecule:2-nitropropane dioxygenase; PDBTitle: crystal structures and site-directed mutagenesis study of nitroalkane2 oxidase from streptomyces ansochromogenes 68 c2gjlA_ not modelled 95.3 11 PDB header:oxidoreductase Chain: A: PDB Molecule:hypothetical protein pa1024; PDBTitle: crystal structure of 2-nitropropane dioxygenase 69 d1jcna1 not modelled 95.3 16 Fold:TIM beta/alpha-barrel Superfamily:Inosine monophosphate dehydrogenase (IMPDH) Family:Inosine monophosphate dehydrogenase (IMPDH) 70 c1qpoA_ not modelled 95.2 12 PDB header:transferase Chain: A: PDB Molecule:quinolinate acid phosphoribosyl transferase; PDBTitle: quinolinate phosphoribosyl transferase (qaprtase) apo-enzyme from2 mycobacterium tuberculosis 71 d1xcfa_ not modelled 95.1 18 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 72 d1mxsa_ not modelled 95.1 19 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 73 c2a7rD_ not modelled 95.1 12 PDB header:oxidoreductase Chain: D: PDB Molecule:gmp reductase 2; PDBTitle: crystal structure of human guanosine monophosphate2 reductase 2 (gmpr2) 74 d2tpsa_ not modelled 95.0 19 Fold:TIM beta/alpha-barrel Superfamily:Thiamin phosphate synthase Family:Thiamin phosphate synthase 75 d1rpxa_ not modelled 94.9 15 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:D-ribulose-5-phosphate 3-epimerase 76 d1qpoa1 not modelled 94.9 10 Fold:TIM beta/alpha-barrel Superfamily:Nicotinate/Quinolinate PRTase C-terminal domain-like Family:NadC C-terminal domain-like 77 d1pvna1 not modelled 94.8 14 Fold:TIM beta/alpha-barrel Superfamily:Inosine monophosphate dehydrogenase (IMPDH) Family:Inosine monophosphate dehydrogenase (IMPDH) 78 c3oa3A_ not modelled 94.8 23 PDB header:lyase Chain: A: PDB Molecule:aldolase; PDBTitle: crystal structure of a putative deoxyribose-phosphate aldolase from2 coccidioides immitis 79 d1qopa_ not modelled 94.7 12 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 80 c3l0gD_ not modelled 94.5 13 PDB header:transferase Chain: D: PDB Molecule:nicotinate-nucleotide pyrophosphorylase; PDBTitle: crystal structure of nicotinate-nucleotide pyrophosphorylase from2 ehrlichia chaffeensis at 2.05a resolution 81 c2z6jB_ not modelled 94.4 15 PDB header:oxidoreductase Chain: B: PDB Molecule:trans-2-enoyl-acp reductase ii; PDBTitle: crystal structure of s. pneumoniae enoyl-acyl carrier2 protein reductase (fabk) in complex with an inhibitor 82 c3ng3A_ not modelled 94.4 25 PDB header:lyase Chain: A: PDB Molecule:deoxyribose-phosphate aldolase; PDBTitle: crystal structure of deoxyribose phosphate aldolase from mycobacterium2 avium 104 in a schiff base with an unknown aldehyde 83 d1tqja_ not modelled 94.1 14 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:D-ribulose-5-phosphate 3-epimerase 84 c1qapA_ not modelled 94.1 14 PDB header:glycosyltransferase Chain: A: PDB Molecule:quinolinic acid phosphoribosyltransferase; PDBTitle: quinolinic acid phosphoribosyltransferase with bound2 quinolinic acid 85 c1ypfB_ not modelled 93.8 14 PDB header:oxidoreductase Chain: B: PDB Molecule:gmp reductase; PDBTitle: crystal structure of guac (ba5705) from bacillus anthracis at 1.8 a2 resolution 86 c3ct7E_ not modelled 93.5 12 PDB header:isomerase Chain: E: PDB Molecule:d-allulose-6-phosphate 3-epimerase; PDBTitle: crystal structure of d-allulose 6-phosphate 3-epimerase2 from escherichia coli k-12 87 d1vcfa1 not modelled 93.3 12 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 88 c3o63B_ not modelled 92.5 16 PDB header:transferase Chain: B: PDB Molecule:probable thiamine-phosphate pyrophosphorylase; PDBTitle: crystal structure of thiamin phosphate synthase from mycobacterium2 tuberculosis 89 c2cu0B_ not modelled 92.3 13 PDB header:oxidoreductase Chain: B: PDB Molecule:inosine-5'-monophosphate dehydrogenase; PDBTitle: crystal structure of inosine-5'-monophosphate dehydrogenase from2 pyrococcus horikoshii ot3 90 d1d3ga_ not modelled 92.2 14 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 91 c2qr6A_ not modelled 91.8 15 PDB header:oxidoreductase Chain: A: PDB Molecule:imp dehydrogenase/gmp reductase; PDBTitle: crystal structure of imp dehydrogenase/gmp reductase-like protein2 (np_599840.1) from corynebacterium glutamicum atcc 13032 kitasato at3 1.50 a resolution 92 d1mzha_ not modelled 91.7 17 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 93 c2zrvC_ not modelled 91.7 12 PDB header:isomerase Chain: C: PDB Molecule:isopentenyl-diphosphate delta-isomerase; PDBTitle: crystal structure of sulfolobus shibatae isopentenyl2 diphosphate isomerase in complex with reduced fmn. 94 d1a53a_ not modelled 91.6 9 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 95 d1o0ya_ not modelled 91.3 23 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 96 d1piia2 not modelled 91.0 15 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 97 d1qapa1 not modelled 90.0 13 Fold:TIM beta/alpha-barrel Superfamily:Nicotinate/Quinolinate PRTase C-terminal domain-like Family:NadC C-terminal domain-like 98 c3noyA_ not modelled 90.0 17 PDB header:oxidoreductase Chain: A: PDB Molecule:4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; PDBTitle: crystal structure of ispg (gcpe) 99 d1tqxa_ not modelled 89.2 7 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:D-ribulose-5-phosphate 3-epimerase 100 c3ngjC_ not modelled 86.1 22 PDB header:lyase Chain: C: PDB Molecule:deoxyribose-phosphate aldolase; PDBTitle: crystal structure of a putative deoxyribose-phosphate aldolase from2 entamoeba histolytica 101 c2y0fD_ not modelled 85.6 15 PDB header:oxidoreductase Chain: D: PDB Molecule:4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; PDBTitle: structure of gcpe (ispg) from thermus thermophilus hb27 102 d1w0ma_ not modelled 85.4 14 Fold:TIM beta/alpha-barrel Superfamily:Triosephosphate isomerase (TIM) Family:Triosephosphate isomerase (TIM) 103 d1h1ya_ not modelled 85.3 14 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:D-ribulose-5-phosphate 3-epimerase 104 c3tfxB_ not modelled 83.8 13 PDB header:lyase Chain: B: PDB Molecule:orotidine 5'-phosphate decarboxylase; PDBTitle: crystal structure of orotidine 5'-phosphate decarboxylase from2 lactobacillus acidophilus 105 d2p10a1 not modelled 83.1 18 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Mll9387-like 106 d1pv8a_ not modelled 83.0 21 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase) 107 d1vcva1 not modelled 82.8 21 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 108 d1n7ka_ not modelled 82.2 20 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 109 c3qjaA_ not modelled 81.9 13 PDB header:lyase Chain: A: PDB Molecule:indole-3-glycerol phosphate synthase; PDBTitle: crystal structure of the mycobacterium tuberculosis indole-3-glycerol2 phosphate synthase (trpc) in apo form 110 c3exsB_ not modelled 81.6 14 PDB header:lyase Chain: B: PDB Molecule:rmpd (hexulose-6-phosphate synthase); PDBTitle: crystal structure of kgpdc from streptococcus mutans in2 complex with d-r5p 111 d2cu0a1 not modelled 81.0 15 Fold:TIM beta/alpha-barrel Superfamily:Inosine monophosphate dehydrogenase (IMPDH) Family:Inosine monophosphate dehydrogenase (IMPDH) 112 c2bdqA_ not modelled 80.8 12 PDB header:metal transport Chain: A: PDB Molecule:copper homeostasis protein cutc; PDBTitle: crystal structure of the putative copper homeostasis2 protein cutc from streptococcus agalactiae, northeast3 strucural genomics target sar15. 113 c1znnF_ not modelled 80.8 17 PDB header:biosynthetic protein Chain: F: PDB Molecule:plp synthase; PDBTitle: structure of the synthase subunit of plp synthase 114 c3navB_ not modelled 79.6 20 PDB header:lyase Chain: B: PDB Molecule:tryptophan synthase alpha chain; PDBTitle: crystal structure of an alpha subunit of tryptophan synthase from2 vibrio cholerae o1 biovar el tor str. n16961 115 d1hg3a_ not modelled 77.7 21 Fold:TIM beta/alpha-barrel Superfamily:Triosephosphate isomerase (TIM) Family:Triosephosphate isomerase (TIM) 116 d1gzga_ not modelled 76.3 39 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase) 117 d1ep3a_ not modelled 75.8 13 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 118 d2c1ha1 not modelled 75.7 27 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase) 119 c1yadD_ not modelled 75.4 15 PDB header:transcription Chain: D: PDB Molecule:regulatory protein teni; PDBTitle: structure of teni from bacillus subtilis 120 c3tqvA_ not modelled 75.1 10 PDB header:transferase Chain: A: PDB Molecule:nicotinate-nucleotide pyrophosphorylase; PDBTitle: structure of the nicotinate-nucleotide pyrophosphorylase from2 francisella tularensis.

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0