Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	R	R	A	G	T	P	T	A	K	K	V	T	Q	L	V	N	V	E	E	H	V	E	G	F	R	Q	V	R	E	A	H	R	R	E	L	I	D	D	Y	V	E	L	I	S	D	L	I	R	E	V	G	E	A	R	Q	V	D	M
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?								?	?	?														?	?	?	?																?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		A	A	R	L	G	V	S	Q	P	T	V	A	K	M	L	K	R	L	A	T	M	G	L	I	E	M	I	P	W	R	G	V	F	L	T	A	E	G	E	K	L	A	Q	E	S	R	E	R	H	Q	I	V	E	N	F	L	L	V	L	G
Secondary structure
SS confidence
Disorder					?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.
Sequence		V	S	P	E	I	A	R	R	D	A	E	G	M	E	H	H	V	S	E	E	T	L	D	A	F	R	L	F	T	Q	K	H	G	A	K
Secondary structure
SS confidence
Disorder																																?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1g3w chain A Region: 34 - 150 Aligned: 117 Modelled: 117 Confidence: 100.0% Identity: 24% PDB header:gene regulation Chain: A: PDB Molecule:diphtheria toxin repressor; PDBTitle: cd-cys102ser dtxr Phyre2 PDB 2h09 chain A Region: 24 - 150 Aligned: 127 Modelled: 127 Confidence: 100.0% Identity: 100% PDB header:transcription Chain: A: PDB Molecule:transcriptional regulator mntr; PDBTitle: crystal structure of diphtheria toxin repressor like protein2 from e. coli Phyre2 PDB 1fx7 chain C Region: 33 - 150 Aligned: 118 Modelled: 118 Confidence: 100.0% Identity: 27% PDB header:signaling protein Chain: C: PDB Molecule:iron-dependent repressor ider; PDBTitle: crystal structure of the iron-dependent regulator (ider)2 from mycobacterium tuberculosis Phyre2 PDB 2it0 chain A Region: 34 - 150 Aligned: 117 Modelled: 117 Confidence: 100.0% Identity: 27% PDB header:transcription/dna Chain: A: PDB Molecule:iron-dependent repressor ider; PDBTitle: crystal structure of a two-domain ider-dna complex crystal2 form ii Phyre2 PDB 3hru chain A Region: 36 - 150 Aligned: 113 Modelled: 115 Confidence: 99.9% Identity: 27% PDB header:transcription Chain: A: PDB Molecule:metalloregulator scar; PDBTitle: crystal structure of scar with bound zn2+ Phyre2 PDB 2ev5 chain B Region: 36 - 151 Aligned: 112 Modelled: 116 Confidence: 99.9% Identity: 36% PDB header:transcription Chain: B: PDB Molecule:transcriptional regulator mntr; PDBTitle: bacillus subtilis manganese transport regulator (mntr)2 bound to calcium Phyre2 PDB 1f5t chain A Region: 33 - 150 Aligned: 118 Modelled: 118 Confidence: 99.9% Identity: 24% PDB header:transcription/dna Chain: A: PDB Molecule:diphtheria toxin repressor; PDBTitle: diphtheria tox repressor (c102d mutant) complexed with2 nickel and dtxr consensus binding sequence Phyre2 PDB 2x4h chain A Region: 35 - 151 Aligned: 116 Modelled: 117 Confidence: 99.9% Identity: 19% PDB header:transcription Chain: A: PDB Molecule:hypothetical protein sso2273; PDBTitle: crystal structure of the hypothetical protein sso2273 from2 sulfolobus solfataricus Phyre2 PDB 2isy chain A domain 1 Region: 33 - 94 Aligned: 62 Modelled: 62 Confidence: 99.5% Identity: 27% Fold: DNA/RNA-binding 3-helical bundle Superfamily: "Winged helix" DNA-binding domain Family: Iron-dependent repressor protein Phyre2 PDB 1g3w chain A domain 1 Region: 34 - 94 Aligned: 61 Modelled: 61 Confidence: 99.5% Identity: 25% Fold: DNA/RNA-binding 3-helical bundle Superfamily: "Winged helix" DNA-binding domain Family: Iron-dependent repressor protein Phyre2 PDB 2fxa chain A domain 1 Region: 44 - 145 Aligned: 102 Modelled: 102 Confidence: 99.5% Identity: 18% Fold: DNA/RNA-binding 3-helical bundle Superfamily: "Winged helix" DNA-binding domain Family: MarR-like transcriptional regulators Phyre2 PDB 2ev0 chain A domain 2 Region: 95 - 150 Aligned: 56 Modelled: 56 Confidence: 99.4% Identity: 36% Fold: Iron-dependent repressor protein, dimerization domain Superfamily: Iron-dependent repressor protein, dimerization domain Family: Iron-dependent repressor protein, dimerization domain Phyre2 PDB 1f5t chain A domain 2 Region: 95 - 150 Aligned: 56 Modelled: 56 Confidence: 99.3% Identity: 23% Fold: Iron-dependent repressor protein, dimerization domain Superfamily: Iron-dependent repressor protein, dimerization domain Family: Iron-dependent repressor protein, dimerization domain Phyre2 PDB 2ev0 chain A domain 1 Region: 35 - 92 Aligned: 55 Modelled: 58 Confidence: 99.3% Identity: 36% Fold: DNA/RNA-binding 3-helical bundle Superfamily: "Winged helix" DNA-binding domain Family: Iron-dependent repressor protein Phyre2 PDB 2hr3 chain A domain 1 Region: 8 - 150 Aligned: 127 Modelled: 127 Confidence: 99.3% Identity: 17% Fold: DNA/RNA-binding 3-helical bundle Superfamily: "Winged helix" DNA-binding domain Family: MarR-like transcriptional regulators Phyre2 PDB 1g3w chain A domain 2 Region: 95 - 150 Aligned: 56 Modelled: 56 Confidence: 99.3% Identity: 23% Fold: Iron-dependent repressor protein, dimerization domain Superfamily: Iron-dependent repressor protein, dimerization domain Family: Iron-dependent repressor protein, dimerization domain Phyre2 PDB 2isy chain A domain 2 Region: 95 - 151 Aligned: 56 Modelled: 57 Confidence: 99.1% Identity: 27% Fold: Iron-dependent repressor protein, dimerization domain Superfamily: Iron-dependent repressor protein, dimerization domain Family: Iron-dependent repressor protein, dimerization domain Phyre2 PDB 3bj6 chain B Region: 9 - 151 Aligned: 126 Modelled: 124 Confidence: 99.0% Identity: 16% PDB header:transcription regulator Chain: B: PDB Molecule:transcriptional regulator, marr family; PDBTitle: crystal structure of marr family transcription regulator sp03579 Phyre2 PDB 2fxa chain B Region: 45 - 150 Aligned: 106 Modelled: 106 Confidence: 99.0% Identity: 17% PDB header:transcription Chain: B: PDB Molecule:protease production regulatory protein hpr; PDBTitle: structure of the protease production regulatory protein hpr from2 bacillus subtilis. Phyre2 PDB 2eth chain A domain 1 Region: 44 - 137 Aligned: 93 Modelled: 92 Confidence: 99.0% Identity: 19% Fold: DNA/RNA-binding 3-helical bundle Superfamily: "Winged helix" DNA-binding domain Family: MarR-like transcriptional regulators Phyre2 PDB 1p4x chain A domain 2 Region: 6 - 110 Aligned: 105 Modelled: 105 Confidence: 98.8% Identity: 10% Fold: DNA/RNA-binding 3-helical bundle Superfamily: "Winged helix" DNA-binding domain Family: MarR-like transcriptional regulators Phyre2 1 c1g3wA_ 2 c2h09A_ 3 c1fx7C_ 4 c2it0A_ 5 c3hruA_ 6 c2ev5B_ 7 c1f5tA_ 8 c2x4hA_ 9 d2isya1 10 d1g3wa1 11 d2fxaa1 12 d2ev0a2 13 d1f5ta2 14 d2ev0a1 15 d2hr3a1 16 d1g3wa2 17 d2isya2 18 c3bj6B_ 19 c2fxaB_ 20 d2etha1 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 d1p4xa2 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 306 307 308 309 310 311 312 313 314 315 316 317 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 336 337 338 339 340 341 342 343 344 345 346 347 348 349 350 351 352 353 354 355 356 357 358 359 360 361 362 363 364 365 366 367 368 369 370 371 372 373 374 375 376 377 378 379 380 381 382 383 384 385 386 387 388 389 390 391 392 393 394 395 396 397 398 399 400 401 402 403 404 405 406 407 408 409 410 411 412 413 414 415 416 417 418 419 420 421 422 423 424 425 426 427 428 429 430 431 432 433 434 435 436 437 438 439 440 441 442 443 444 445 446 447 448 449 450 451 452 453 454 455 456 457 458 459 460 461 462 463 464 465 466 467 468 469 470 471 472 473 474 475 476 477 478 479 480 481 482 483 484 485 486 487 488 489 490 491 492 493 494 495 496 497 498 499