Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	N	W	P	Y	P	R	I	V	A	H	R	G	G	G	K	L	A	P	E	N	T	L	A	S	I	D	V	G	A	K	Y	G	H	K	M	I	E	F	D	A	K	L	S	K	D	G	E	I	F	L	L	H	D	D	N	L	E	R
Secondary structure
SS confidence
Disorder		?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		T	S	N	G	W	G	V	A	G	E	L	N	W	Q	D	L	L	R	V	D	A	G	S	W	Y	S	K	M	F	K	G	E	P	L	P	L	L	S	Q	V	A	E	R	C	R	E	H	G	M	M	A	N	I	E	I	K	P	T	T	G
Secondary structure
SS confidence
Disorder																													?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		T	G	P	L	T	G	K	M	V	A	L	A	A	R	E	L	W	A	G	M	T	P	P	L	L	S	S	F	E	I	D	A	L	E	A	A	Q	Q	A	A	P	E	L	P	R	G	L	L	L	D	E	W	R	D	D	W	R	E	L	T
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		A	R	L	G	C	V	S	I	H	L	N	H	K	L	L	N	K	A	R	V	M	Q	L	K	D	A	G	L	R	I	L	V	Y	T	V	N	K	P	Q	R	A	A	E	L	L	R	W	G	V	D	C	I	C	T	D	A	I	D	V	I
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.
Sequence		G	P	N	F	T	A	Q
Secondary structure
SS confidence
Disorder						?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2otd chain C Region: 2 - 246 Aligned: 245 Modelled: 245 Confidence: 100.0% Identity: 96% PDB header:hydrolase Chain: C: PDB Molecule:glycerophosphodiester phosphodiesterase; PDBTitle: the crystal structure of the glycerophosphodiester phosphodiesterase2 from shigella flexneri 2a Phyre2 PDB 3qvq chain B Region: 1 - 246 Aligned: 246 Modelled: 246 Confidence: 100.0% Identity: 32% PDB header:hydrolase Chain: B: PDB Molecule:phosphodiesterase olei02445; PDBTitle: the structure of an oleispira antarctica phosphodiesterase olei024452 in complex with the product sn-glycerol-3-phosphate Phyre2 PDB 2pz0 chain B Region: 6 - 247 Aligned: 241 Modelled: 242 Confidence: 100.0% Identity: 28% PDB header:hydrolase Chain: B: PDB Molecule:glycerophosphoryl diester phosphodiesterase; PDBTitle: crystal structure of glycerophosphodiester phosphodiesterase (gdpd)2 from t. tengcongensis Phyre2 PDB 2p76 chain H Region: 6 - 245 Aligned: 239 Modelled: 240 Confidence: 100.0% Identity: 24% PDB header:hydrolase Chain: H: PDB Molecule:glycerophosphoryl diester phosphodiesterase; PDBTitle: crystal structure of a glycerophosphodiester phosphodiesterase from2 staphylococcus aureus Phyre2 PDB 1zcc chain A domain 1 Region: 7 - 246 Aligned: 232 Modelled: 240 Confidence: 100.0% Identity: 28% Fold: TIM beta/alpha-barrel Superfamily: PLC-like phosphodiesterases Family: Glycerophosphoryl diester phosphodiesterase Phyre2 PDB 3l12 chain A Region: 2 - 247 Aligned: 246 Modelled: 245 Confidence: 100.0% Identity: 23% PDB header:hydrolase Chain: A: PDB Molecule:putative glycerophosphoryl diester phosphodiesterase; PDBTitle: crystal structure of putative glycerophosphoryl diester2 phosphodiesterase (yp_165505.1) from silicibacter pomeroyi dss-3 at3 1.60 a resolution Phyre2 PDB 3ks6 chain A Region: 6 - 245 Aligned: 235 Modelled: 239 Confidence: 100.0% Identity: 20% PDB header:hydrolase Chain: A: PDB Molecule:glycerophosphoryl diester phosphodiesterase; PDBTitle: crystal structure of putative glycerophosphoryl diester2 phosphodiesterase (17743486) from agrobacterium tumefaciens3 str. c58 (dupont) at 1.80 a resolution Phyre2 PDB 1vd6 chain A domain 1 Region: 7 - 242 Aligned: 213 Modelled: 236 Confidence: 100.0% Identity: 31% Fold: TIM beta/alpha-barrel Superfamily: PLC-like phosphodiesterases Family: Glycerophosphoryl diester phosphodiesterase Phyre2 PDB 2o55 chain A Region: 7 - 246 Aligned: 233 Modelled: 233 Confidence: 100.0% Identity: 26% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative glycerophosphodiester phosphodiesterase; PDBTitle: crystal structure of a putative glycerophosphodiester2 phosphodiesterase from galdieria sulphuraria Phyre2 PDB 3no3 chain A Region: 3 - 247 Aligned: 232 Modelled: 245 Confidence: 100.0% Identity: 21% PDB header:hydrolase Chain: A: PDB Molecule:glycerophosphodiester phosphodiesterase; PDBTitle: crystal structure of a glycerophosphodiester phosphodiesterase2 (bdi_0402) from parabacteroides distasonis atcc 8503 at 1.89 a3 resolution Phyre2 PDB 3mz2 chain A Region: 6 - 246 Aligned: 232 Modelled: 241 Confidence: 100.0% Identity: 19% PDB header:hydrolase Chain: A: PDB Molecule:glycerophosphoryl diester phosphodiesterase; PDBTitle: crystal structure of a glycerophosphoryl diester phosphodiesterase2 (bdi_3922) from parabacteroides distasonis atcc 8503 at 1.55 a3 resolution Phyre2 PDB 1ydy chain A domain 1 Region: 6 - 244 Aligned: 239 Modelled: 239 Confidence: 100.0% Identity: 20% Fold: TIM beta/alpha-barrel Superfamily: PLC-like phosphodiesterases Family: Glycerophosphoryl diester phosphodiesterase Phyre2 PDB 1ydy chain A Region: 6 - 244 Aligned: 239 Modelled: 239 Confidence: 100.0% Identity: 20% PDB header:hydrolase Chain: A: PDB Molecule:glycerophosphoryl diester phosphodiesterase; PDBTitle: crystal structure of periplasmic glycerophosphodiester2 phosphodiesterase from escherichia coli Phyre2 PDB 1o1z chain A Region: 6 - 242 Aligned: 213 Modelled: 237 Confidence: 100.0% Identity: 23% Fold: TIM beta/alpha-barrel Superfamily: PLC-like phosphodiesterases Family: Glycerophosphoryl diester phosphodiesterase Phyre2 PDB 3ch0 chain A Region: 7 - 242 Aligned: 236 Modelled: 236 Confidence: 100.0% Identity: 25% PDB header:hydrolase Chain: A: PDB Molecule:glycerophosphodiester phosphodiesterase; PDBTitle: crystal structure of glycerophosphoryl diester phosphodiesterase2 (yp_677622.1) from cytophaga hutchinsonii atcc 33406 at 1.50 a3 resolution Phyre2 PDB 3i10 chain A Region: 6 - 247 Aligned: 233 Modelled: 242 Confidence: 100.0% Identity: 18% PDB header:hydrolase Chain: A: PDB Molecule:putative glycerophosphoryl diester phosphodiesterase; PDBTitle: crystal structure of putative glycerophosphoryl diester2 phosphodiesterase (np_812074.1) from bacteroides thetaiotaomicron3 vpi-5482 at 1.35 a resolution Phyre2 PDB 3rlh chain A Region: 6 - 247 Aligned: 226 Modelled: 241 Confidence: 100.0% Identity: 15% PDB header:hydrolase Chain: A: PDB Molecule:sphingomyelin phosphodiesterase d lisictox-alphaia1a; PDBTitle: crystal structure of a class ii phospholipase d from loxosceles2 intermedia venom Phyre2 PDB 3rlg chain A Region: 6 - 247 Aligned: 226 Modelled: 242 Confidence: 100.0% Identity: 16% PDB header:hydrolase Chain: A: PDB Molecule:sphingomyelin phosphodiesterase d lisictox-alphaia1a; PDBTitle: crystal structure of loxosceles intermedia phospholipase d isoform 12 h12a mutant Phyre2 PDB 2f9r chain C Region: 6 - 247 Aligned: 217 Modelled: 224 Confidence: 100.0% Identity: 16% PDB header:hydrolase Chain: C: PDB Molecule:sphingomyelinase d 1; PDBTitle: crystal structure of the inactive state of the smase i, a2 sphingomyelinase d from loxosceles laeta venom Phyre2 PDB 1djy chain B Region: 15 - 58 Aligned: 44 Modelled: 44 Confidence: 97.5% Identity: 14% PDB header:lipid degradation Chain: B: PDB Molecule:phosphoinositide-specific phospholipase c, PDBTitle: phosphoinositide-specific phospholipase c-delta1 from rat2 complexed with inositol-2,4,5-trisphosphate Phyre2 1 c2otdC_ 2 c3qvqB_ 3 c2pz0B_ 4 c2p76H_ 5 d1zcca1 6 c3l12A_ 7 c3ks6A_ 8 d1vd6a1 9 c2o55A_ 10 c3no3A_ 11 c3mz2A_ 12 d1ydya1 13 c1ydyA_ 14 d1o1za_ 15 c3ch0A_ 16 c3i10A_ 17 c3rlhA_ 18 c3rlgA_ 19 c2f9rC_ 20 c1djyB_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2otdC_ 100.0 96 PDB header:hydrolase Chain: C: PDB Molecule:glycerophosphodiester phosphodiesterase; PDBTitle: the crystal structure of the glycerophosphodiester phosphodiesterase2 from shigella flexneri 2a 2 c3qvqB_ 100.0 32 PDB header:hydrolase Chain: B: PDB Molecule:phosphodiesterase olei02445; PDBTitle: the structure of an oleispira antarctica phosphodiesterase olei024452 in complex with the product sn-glycerol-3-phosphate 3 c2pz0B_ 100.0 28 PDB header:hydrolase Chain: B: PDB Molecule:glycerophosphoryl diester phosphodiesterase; PDBTitle: crystal structure of glycerophosphodiester phosphodiesterase (gdpd)2 from t. tengcongensis 4 c2p76H_ 100.0 24 PDB header:hydrolase Chain: H: PDB Molecule:glycerophosphoryl diester phosphodiesterase; PDBTitle: crystal structure of a glycerophosphodiester phosphodiesterase from2 staphylococcus aureus 5 d1zcca1 100.0 28 Fold:TIM beta/alpha-barrel Superfamily:PLC-like phosphodiesterases Family:Glycerophosphoryl diester phosphodiesterase 6 c3l12A_ 100.0 23 PDB header:hydrolase Chain: A: PDB Molecule:putative glycerophosphoryl diester phosphodiesterase; PDBTitle: crystal structure of putative glycerophosphoryl diester2 phosphodiesterase (yp_165505.1) from silicibacter pomeroyi dss-3 at3 1.60 a resolution 7 c3ks6A_ 100.0 20 PDB header:hydrolase Chain: A: PDB Molecule:glycerophosphoryl diester phosphodiesterase; PDBTitle: crystal structure of putative glycerophosphoryl diester2 phosphodiesterase (17743486) from agrobacterium tumefaciens3 str. c58 (dupont) at 1.80 a resolution 8 d1vd6a1 100.0 31 Fold:TIM beta/alpha-barrel Superfamily:PLC-like phosphodiesterases Family:Glycerophosphoryl diester phosphodiesterase 9 c2o55A_ 100.0 26 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative glycerophosphodiester phosphodiesterase; PDBTitle: crystal structure of a putative glycerophosphodiester2 phosphodiesterase from galdieria sulphuraria 10 c3no3A_ 100.0 21 PDB header:hydrolase Chain: A: PDB Molecule:glycerophosphodiester phosphodiesterase; PDBTitle: crystal structure of a glycerophosphodiester phosphodiesterase2 (bdi_0402) from parabacteroides distasonis atcc 8503 at 1.89 a3 resolution 11 c3mz2A_ 100.0 19 PDB header:hydrolase Chain: A: PDB Molecule:glycerophosphoryl diester phosphodiesterase; PDBTitle: crystal structure of a glycerophosphoryl diester phosphodiesterase2 (bdi_3922) from parabacteroides distasonis atcc 8503 at 1.55 a3 resolution 12 d1ydya1 100.0 20 Fold:TIM beta/alpha-barrel Superfamily:PLC-like phosphodiesterases Family:Glycerophosphoryl diester phosphodiesterase 13 c1ydyA_ 100.0 20 PDB header:hydrolase Chain: A: PDB Molecule:glycerophosphoryl diester phosphodiesterase; PDBTitle: crystal structure of periplasmic glycerophosphodiester2 phosphodiesterase from escherichia coli 14 d1o1za_ 100.0 23 Fold:TIM beta/alpha-barrel Superfamily:PLC-like phosphodiesterases Family:Glycerophosphoryl diester phosphodiesterase 15 c3ch0A_ 100.0 25 PDB header:hydrolase Chain: A: PDB Molecule:glycerophosphodiester phosphodiesterase; PDBTitle: crystal structure of glycerophosphoryl diester phosphodiesterase2 (yp_677622.1) from cytophaga hutchinsonii atcc 33406 at 1.50 a3 resolution 16 c3i10A_ 100.0 18 PDB header:hydrolase Chain: A: PDB Molecule:putative glycerophosphoryl diester phosphodiesterase; PDBTitle: crystal structure of putative glycerophosphoryl diester2 phosphodiesterase (np_812074.1) from bacteroides thetaiotaomicron3 vpi-5482 at 1.35 a resolution 17 c3rlhA_ 100.0 15 PDB header:hydrolase Chain: A: PDB Molecule:sphingomyelin phosphodiesterase d lisictox-alphaia1a; PDBTitle: crystal structure of a class ii phospholipase d from loxosceles2 intermedia venom 18 c3rlgA_ 100.0 16 PDB header:hydrolase Chain: A: PDB Molecule:sphingomyelin phosphodiesterase d lisictox-alphaia1a; PDBTitle: crystal structure of loxosceles intermedia phospholipase d isoform 12 h12a mutant 19 c2f9rC_ 100.0 16 PDB header:hydrolase Chain: C: PDB Molecule:sphingomyelinase d 1; PDBTitle: crystal structure of the inactive state of the smase i, a2 sphingomyelinase d from loxosceles laeta venom 20 c1djyB_ 97.5 14 PDB header:lipid degradation Chain: B: PDB Molecule:phosphoinositide-specific phospholipase c, PDBTitle: phosphoinositide-specific phospholipase c-delta1 from rat2 complexed with inositol-2,4,5-trisphosphate 21 d1qasa3 not modelled 97.4 14 Fold:TIM beta/alpha-barrel Superfamily:PLC-like phosphodiesterases Family:Mammalian PLC 22 d2zkmx4 not modelled 97.4 18 Fold:TIM beta/alpha-barrel Superfamily:PLC-like phosphodiesterases Family:Mammalian PLC 23 c3qr0A_ not modelled 97.3 23 PDB header:hydrolase Chain: A: PDB Molecule:phospholipase c-beta (plc-beta); PDBTitle: crystal structure of s. officinalis plc21 24 c2fjuB_ not modelled 97.3 16 PDB header:signaling protein,apoptosis/hydrolase Chain: B: PDB Molecule:1-phosphatidylinositol-4,5-bisphosphate PDBTitle: activated rac1 bound to its effector phospholipase c beta 2 25 c3ohmB_ not modelled 97.2 16 PDB header:signaling protein / hydrolase Chain: B: PDB Molecule:1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase PDBTitle: crystal structure of activated g alpha q bound to its effector2 phospholipase c beta 3 26 c3ktsA_ not modelled 95.8 11 PDB header:transcriptional regulator Chain: A: PDB Molecule:glycerol uptake operon antiterminator regulatory protein; PDBTitle: crystal structure of glycerol uptake operon antiterminator regulatory2 protein from listeria monocytogenes str. 4b f2365 27 d1qopa_ not modelled 95.8 17 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 28 c3navB_ not modelled 95.0 16 PDB header:lyase Chain: B: PDB Molecule:tryptophan synthase alpha chain; PDBTitle: crystal structure of an alpha subunit of tryptophan synthase from2 vibrio cholerae o1 biovar el tor str. n16961 29 c3pjwA_ not modelled 93.9 14 PDB header:lyase Chain: A: PDB Molecule:cyclic dimeric gmp binding protein; PDBTitle: structure of pseudomonas fluorescence lapd ggdef-eal dual domain, i23 30 d1vhca_ not modelled 93.6 18 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 31 c3pfmA_ not modelled 93.3 15 PDB header:signaling protein Chain: A: PDB Molecule:ggdef domain protein; PDBTitle: crystal structure of a eal domain of ggdef domain protein from2 pseudomonas fluorescens pf 32 d1a53a_ not modelled 92.3 12 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 33 d1wbha1 not modelled 92.2 11 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 34 d1vkfa_ not modelled 92.2 22 Fold:TIM beta/alpha-barrel Superfamily:GlpP-like Family:GlpP-like 35 c3a24A_ not modelled 91.5 15 PDB header:hydrolase Chain: A: PDB Molecule:alpha-galactosidase; PDBTitle: crystal structure of bt1871 retaining glycosidase 36 c2c3zA_ not modelled 91.3 13 PDB header:lyase Chain: A: PDB Molecule:indole-3-glycerol phosphate synthase; PDBTitle: crystal structure of a truncated variant of indole-3-2 glycerol phosphate synthase from sulfolobus solfataricus 37 d1geqa_ not modelled 91.2 12 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 38 c2zq0B_ not modelled 90.3 10 PDB header:hydrolase Chain: B: PDB Molecule:alpha-glucosidase (alpha-glucosidase susb); PDBTitle: crystal structure of susb complexed with acarbose 39 c3gfzB_ not modelled 89.7 17 PDB header:hydrolase, signaling protein Chain: B: PDB Molecule:klebsiella pneumoniae blrp1; PDBTitle: klebsiella pneumoniae blrp1 ph 6 manganese/cy-digmp complex 40 d1rd5a_ not modelled 89.7 15 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 41 c3h4wA_ not modelled 89.1 17 PDB header:hydrolase Chain: A: PDB Molecule:phosphatidylinositol-specific phospholipase c1; PDBTitle: structure of a ca+2 dependent phosphatidylinositol-specific2 phospholipase c (pi-plc) enzyme from streptomyces antibioticus 42 d1vc4a_ not modelled 89.1 20 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 43 c3hvbB_ not modelled 88.5 14 PDB header:hydrolase Chain: B: PDB Molecule:protein fimx; PDBTitle: crystal structure of the dual-domain ggdef-eal module of2 fimx from pseudomonas aeruginosa 44 c2yw3E_ not modelled 88.2 13 PDB header:lyase Chain: E: PDB Molecule:4-hydroxy-2-oxoglutarate aldolase/2-deydro-3- PDBTitle: crystal structure analysis of the 4-hydroxy-2-oxoglutarate aldolase/2-2 deydro-3-deoxyphosphogluconate aldolase from tthb1 45 d1mxsa_ not modelled 88.2 10 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 46 d1i4na_ not modelled 85.6 18 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 47 d1piia2 not modelled 84.5 12 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 48 c3kzpA_ not modelled 83.1 14 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative diguanylate cyclase/phosphodiesterase; PDBTitle: crystal structure of putative diguanylate cyclase/phosphodiesterase2 from listaria monocytigenes 49 c3labA_ not modelled 82.4 19 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative kdpg (2-keto-3-deoxy-6-phosphogluconate) PDBTitle: crystal structure of a putative kdpg (2-keto-3-deoxy-6-2 phosphogluconate) aldolase from oleispira antarctica 50 c2p10D_ not modelled 81.3 17 PDB header:hydrolase Chain: D: PDB Molecule:mll9387 protein; PDBTitle: crystal structure of a putative phosphonopyruvate hydrolase (mll9387)2 from mesorhizobium loti maff303099 at 2.15 a resolution 51 c3bo9B_ not modelled 80.9 14 PDB header:oxidoreductase Chain: B: PDB Molecule:putative nitroalkan dioxygenase; PDBTitle: crystal structure of putative nitroalkan dioxygenase (tm0800) from2 thermotoga maritima at 2.71 a resolution 52 c3qjaA_ not modelled 80.3 21 PDB header:lyase Chain: A: PDB Molecule:indole-3-glycerol phosphate synthase; PDBTitle: crystal structure of the mycobacterium tuberculosis indole-3-glycerol2 phosphate synthase (trpc) in apo form 53 d2p10a1 not modelled 79.7 16 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Mll9387-like 54 c2htmB_ not modelled 76.3 17 PDB header:biosynthetic protein Chain: B: PDB Molecule:thiazole biosynthesis protein thig; PDBTitle: crystal structure of ttha0676 from thermus thermophilus hb8 55 d1ujpa_ not modelled 76.2 18 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 56 d2basa1 not modelled 76.2 10 Fold:TIM beta/alpha-barrel Superfamily:EAL domain-like Family:EAL domain 57 c3s83A_ not modelled 75.8 22 PDB header:signaling protein Chain: A: PDB Molecule:ggdef family protein; PDBTitle: crystal structure of eal domain from caulobacter crescentus cb15 58 c3ct7E_ not modelled 75.7 14 PDB header:isomerase Chain: E: PDB Molecule:d-allulose-6-phosphate 3-epimerase; PDBTitle: crystal structure of d-allulose 6-phosphate 3-epimerase2 from escherichia coli k-12 59 c2r6oB_ not modelled 73.7 10 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative diguanylate cyclase/phosphodiesterase (ggdef & eal PDBTitle: crystal structure of putative diguanylate cyclase/phosphodiesterase2 from thiobacillus denitrificans 60 d1xm3a_ not modelled 73.4 31 Fold:TIM beta/alpha-barrel Superfamily:ThiG-like Family:ThiG-like 61 c2v82A_ not modelled 72.9 14 PDB header:lyase Chain: A: PDB Molecule:2-dehydro-3-deoxy-6-phosphogalactonate aldolase; PDBTitle: kdpgal complexed to kdpgal 62 c3igsB_ not modelled 68.8 17 PDB header:isomerase Chain: B: PDB Molecule:n-acetylmannosamine-6-phosphate 2-epimerase 2; PDBTitle: structure of the salmonella enterica n-acetylmannosamine-6-phosphate2 2-epimerase 63 c2zbtB_ not modelled 68.7 23 PDB header:lyase Chain: B: PDB Molecule:pyridoxal biosynthesis lyase pdxs; PDBTitle: crystal structure of pyridoxine biosynthesis protein from thermus2 thermophilus hb8 64 d1j5ta_ not modelled 68.6 15 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 65 c2gjlA_ not modelled 68.3 16 PDB header:oxidoreductase Chain: A: PDB Molecule:hypothetical protein pa1024; PDBTitle: crystal structure of 2-nitropropane dioxygenase 66 c3femB_ not modelled 65.8 23 PDB header:biosynthetic protein, transferase Chain: B: PDB Molecule:pyridoxine biosynthesis protein snz1; PDBTitle: structure of the synthase subunit pdx1.1 (snz1) of plp synthase from2 saccharomyces cerevisiae 67 c3gkaB_ not modelled 65.6 21 PDB header:oxidoreductase Chain: B: PDB Molecule:n-ethylmaleimide reductase; PDBTitle: crystal structure of n-ethylmaleimidine reductase from2 burkholderia pseudomallei 68 c3nhzA_ not modelled 65.1 14 PDB header:dna binding protein Chain: A: PDB Molecule:two component system transcriptional regulator mtra; PDBTitle: structure of n-terminal domain of mtra 69 d1wv2a_ not modelled 64.8 28 Fold:TIM beta/alpha-barrel Superfamily:ThiG-like Family:ThiG-like 70 c2nv2U_ not modelled 64.6 26 PDB header:lyase/transferase Chain: U: PDB Molecule:pyridoxal biosynthesis lyase pdxs; PDBTitle: structure of the plp synthase complex pdx1/2 (yaad/e) from bacillus2 subtilis 71 d1wa3a1 not modelled 64.0 13 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 72 d7reqa2 not modelled 63.8 20 Fold:Flavodoxin-like Superfamily:Cobalamin (vitamin B12)-binding domain Family:Cobalamin (vitamin B12)-binding domain 73 c3ffsC_ not modelled 63.7 22 PDB header:oxidoreductase Chain: C: PDB Molecule:inosine-5-monophosphate dehydrogenase; PDBTitle: the crystal structure of cryptosporidium parvum inosine-5'-2 monophosphate dehydrogenase 74 c3bw2A_ not modelled 63.1 18 PDB header:oxidoreductase Chain: A: PDB Molecule:2-nitropropane dioxygenase; PDBTitle: crystal structures and site-directed mutagenesis study of nitroalkane2 oxidase from streptomyces ansochromogenes 75 d2ptda_ not modelled 62.6 21 Fold:TIM beta/alpha-barrel Superfamily:PLC-like phosphodiesterases Family:Bacterial PLC 76 c3jr2D_ not modelled 62.1 11 PDB header:biosynthetic protein Chain: D: PDB Molecule:hexulose-6-phosphate synthase sgbh; PDBTitle: x-ray crystal structure of the mg-bound 3-keto-l-gulonate-6-phosphate2 decarboxylase from vibrio cholerae o1 biovar el tor str. n16961 77 c1piiA_ not modelled 61.3 13 PDB header:bifunctional(isomerase and synthase) Chain: A: PDB Molecule:n-(5'phosphoribosyl)anthranilate isomerase; PDBTitle: three-dimensional structure of the bifunctional enzyme2 phosphoribosylanthranilate isomerase:3 indoleglycerolphosphate synthase from escherichia coli4 refined at 2.0 angstroms resolution 78 c2z6jB_ not modelled 60.5 11 PDB header:oxidoreductase Chain: B: PDB Molecule:trans-2-enoyl-acp reductase ii; PDBTitle: crystal structure of s. pneumoniae enoyl-acyl carrier2 protein reductase (fabk) in complex with an inhibitor 79 c3gndC_ not modelled 59.1 18 PDB header:lyase Chain: C: PDB Molecule:aldolase lsrf; PDBTitle: crystal structure of e. coli lsrf in complex with ribulose-5-phosphate 80 c3hv9A_ not modelled 57.7 15 PDB header:hydrolase Chain: A: PDB Molecule:protein fimx; PDBTitle: crystal structure of fimx eal domain from pseudomonas aeruginosa 81 c3gk0H_ not modelled 55.4 25 PDB header:transferase Chain: H: PDB Molecule:pyridoxine 5'-phosphate synthase; PDBTitle: crystal structure of pyridoxal phosphate biosynthetic2 protein from burkholderia pseudomallei 82 c2ekcA_ not modelled 55.1 16 PDB header:lyase Chain: A: PDB Molecule:tryptophan synthase alpha chain; PDBTitle: structural study of project id aq_1548 from aquifex aeolicus vf5 83 c3qz6A_ not modelled 52.8 12 PDB header:lyase Chain: A: PDB Molecule:hpch/hpai aldolase; PDBTitle: the crystal structure of hpch/hpai aldolase from desulfitobacterium2 hafniense dcb-2 84 d1h7na_ not modelled 52.3 18 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase) 85 d2flia1 not modelled 51.4 20 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:D-ribulose-5-phosphate 3-epimerase 86 d1m5wa_ not modelled 51.4 17 Fold:TIM beta/alpha-barrel Superfamily:Pyridoxine 5'-phosphate synthase Family:Pyridoxine 5'-phosphate synthase 87 c2vwtA_ not modelled 51.1 16 PDB header:lyase Chain: A: PDB Molecule:yfau, 2-keto-3-deoxy sugar aldolase; PDBTitle: crystal structure of yfau, a metal ion dependent class ii2 aldolase from escherichia coli k12 - mg-pyruvate product3 complex 88 c2qjhH_ not modelled 49.9 15 PDB header:lyase Chain: H: PDB Molecule:putative aldolase mj0400; PDBTitle: m. jannaschii adh synthase covalently bound to2 dihydroxyacetone phosphate 89 c3inpA_ not modelled 47.9 16 PDB header:isomerase Chain: A: PDB Molecule:d-ribulose-phosphate 3-epimerase; PDBTitle: 2.05 angstrom resolution crystal structure of d-ribulose-phosphate 3-2 epimerase from francisella tularensis. 90 d1nsja_ not modelled 47.4 13 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 91 d2obba1 not modelled 45.0 17 Fold:HAD-like Superfamily:HAD-like Family:BT0820-like 92 d2c1ha1 not modelled 43.8 18 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase) 93 c3qc3B_ not modelled 43.4 10 PDB header:isomerase Chain: B: PDB Molecule:d-ribulose-5-phosphate-3-epimerase; PDBTitle: crystal structure of a d-ribulose-5-phosphate-3-epimerase (np_954699)2 from homo sapiens at 2.20 a resolution 94 d1pv8a_ not modelled 43.1 20 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase) 95 c2rbgB_ not modelled 42.1 20 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative uncharacterized protein st0493; PDBTitle: crystal structure of hypothetical protein(st0493) from2 sulfolobus tokodaii 96 c1yadD_ not modelled 41.8 13 PDB header:transcription Chain: D: PDB Molecule:regulatory protein teni; PDBTitle: structure of teni from bacillus subtilis 97 c3thaB_ not modelled 41.4 14 PDB header:lyase Chain: B: PDB Molecule:tryptophan synthase alpha chain; PDBTitle: tryptophan synthase subunit alpha from campylobacter jejuni. 98 c2w27A_ not modelled 41.3 10 PDB header:signaling protein Chain: A: PDB Molecule:ykui protein; PDBTitle: crystal structure of the bacillus subtilis ykui protein,2 with an eal domain, in complex with substrate c-di-gmp and3 calcium 99 c3hf3A_ not modelled 39.9 22 PDB header:oxidoreductase Chain: A: PDB Molecule:chromate reductase; PDBTitle: old yellow enzyme from thermus scotoductus sa-01 100 d1gzga_ not modelled 39.0 19 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase) 101 c2h6rG_ not modelled 37.9 12 PDB header:isomerase Chain: G: PDB Molecule:triosephosphate isomerase; PDBTitle: crystal structure of triosephosphate isomerase (tim) from2 methanocaldococcus jannaschii 102 d1rpxa_ not modelled 37.5 14 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:D-ribulose-5-phosphate 3-epimerase 103 d1ru8a_ not modelled 37.3 18 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:N-type ATP pyrophosphatases 104 c3obkH_ not modelled 35.5 15 PDB header:lyase Chain: H: PDB Molecule:delta-aminolevulinic acid dehydratase; PDBTitle: crystal structure of delta-aminolevulinic acid dehydratase2 (porphobilinogen synthase) from toxoplasma gondii me49 in complex3 with the reaction product porphobilinogen 105 d1mvoa_ not modelled 35.3 15 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 106 c3tdmD_ not modelled 35.2 19 PDB header:de novo protein Chain: D: PDB Molecule:computationally designed two-fold symmetric tim-barrel PDBTitle: computationally designed tim-barrel protein, halfflr 107 d1yxya1 not modelled 35.2 16 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:NanE-like 108 d1a77a2 not modelled 34.8 14 Fold:PIN domain-like Superfamily:PIN domain-like Family:5' to 3' exonuclease catalytic domain 109 d1b43a2 not modelled 34.4 18 Fold:PIN domain-like Superfamily:PIN domain-like Family:5' to 3' exonuclease catalytic domain 110 d7odca2 not modelled 34.2 13 Fold:TIM beta/alpha-barrel Superfamily:PLP-binding barrel Family:Alanine racemase-like, N-terminal domain 111 c3rysA_ not modelled 33.0 16 PDB header:hydrolase Chain: A: PDB Molecule:adenosine deaminase 1; PDBTitle: the crystal structure of adenine deaminase (aaur1117) from2 arthrobacter aurescens 112 c1jcnA_ not modelled 32.1 13 PDB header:oxidoreductase Chain: A: PDB Molecule:inosine monophosphate dehydrogenase i; PDBTitle: binary complex of human type-i inosine monophosphate dehydrogenase2 with 6-cl-imp 113 c3c85A_ not modelled 32.1 17 PDB header:transport protein Chain: A: PDB Molecule:putative glutathione-regulated potassium-efflux system PDBTitle: crystal structure of trka domain of putative glutathione-regulated2 potassium-efflux kefb from vibrio parahaemolyticus 114 d1p3da1 not modelled 32.0 16 Fold:MurCD N-terminal domain Superfamily:MurCD N-terminal domain Family:MurCD N-terminal domain 115 d1oy0a_ not modelled 31.8 12 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Ketopantoate hydroxymethyltransferase PanB 116 d1zesa1 not modelled 31.7 16 Fold:Flavodoxin-like Superfamily:CheY-like Family:CheY-related 117 d2d13a1 not modelled 31.4 15 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Adenine nucleotide alpha hydrolases-like Family:N-type ATP pyrophosphatases 118 c3o63B_ not modelled 30.9 14 PDB header:transferase Chain: B: PDB Molecule:probable thiamine-phosphate pyrophosphorylase; PDBTitle: crystal structure of thiamin phosphate synthase from mycobacterium2 tuberculosis 119 d1qpoa1 not modelled 30.8 17 Fold:TIM beta/alpha-barrel Superfamily:Nicotinate/Quinolinate PRTase C-terminal domain-like Family:NadC C-terminal domain-like 120 c2qr6A_ not modelled 30.3 16 PDB header:oxidoreductase Chain: A: PDB Molecule:imp dehydrogenase/gmp reductase; PDBTitle: crystal structure of imp dehydrogenase/gmp reductase-like protein2 (np_599840.1) from corynebacterium glutamicum atcc 13032 kitasato at3 1.50 a resolution

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0