PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c2vwtA_

Fold library id	PDB Header	Molecule	Title
c2vwtA_	PDB header: lyase	Chain: A: PDB Molecule: yfau, 2-keto-3-deoxy sugar aldolase;	PDBTitle: crystal structure of yfau, a metal ion dependent class ii2 aldolase from escherichia coli k12 - mg-pyruvate product3 complex

Links to external resources
Added to library: Tue Mar 16 14:02:37 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence M N A L L S N P F K E R L R K G E V Q I G L W L S S T T A Y M A E I A A T S G Y D W L L I D G E H A P N T I Q D L Y H Q L Q A V A P Y A S Q

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S
T T
S
T T
S T T T S
T T S S S

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence P V I R P V E G S K P L I K Q V L D I G A Q T L L I P M V D T A E Q A R Q V V S A T R Y P P Y G E R G V G A S V A R A A R W G R I E N Y M A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S
T T
S
S S
T T T
S
G G G S G G G G G G T S T T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence Q V N D S L C L L V Q V E S K T A L D N L D E I L D V E G I D G V F I G P A D L S A S L G Y P D N A G H P E V Q R I I E T S I R R I R A A G

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S T T S T T
T T
T T
T T S T T

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . .

Sequence K A A G F L A V A P D M A Q Q C L A W G A N F V A V G V D T M L Y S D A L D Q R L A M F K S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S S T T
T T

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

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Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	M	N	A	L	L	S	N	P	F	K	E	R	L	R	K	G	E	V	Q	I	G	L	W	L	S	S	T	T	A	Y	M	A	E	I	A	A	T	S	G	Y	D	W	L	L	I	D	G	E	H	A	P	N	T	I	Q	D	L	Y	H	Q	L	Q	A	V	A	P	Y	A	S	Q
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			S	S											T	T										S											T	T			S						T	T	T	S															T	T	S	S	S
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	P	V	I	R	P	V	E	G	S	K	P	L	I	K	Q	V	L	D	I	G	A	Q	T	L	L	I	P	M	V	D	T	A	E	Q	A	R	Q	V	V	S	A	T	R	Y	P	P	Y	G	E	R	G	V	G	A	S	V	A	R	A	A	R	W	G	R	I	E	N	Y	M	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)						S	S												T	T							S				S												S		T	T	T					S		G	G	G	S	G	G	G	G	G	G	T	S	T	T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	Q	V	N	D	S	L	C	L	L	V	Q	V	E	S	K	T	A	L	D	N	L	D	E	I	L	D	V	E	G	I	D	G	V	F	I	G	P	A	D	L	S	A	S	L	G	Y	P	D	N	A	G	H	P	E	V	Q	R	I	I	E	T	S	I	R	R	I	R	A	A	G
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)														S						T						T	S	T	T															T	T		T	T		T	T	S																	T	T
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.
Sequence	K	A	A	G	F	L	A	V	A	P	D	M	A	Q	Q	C	L	A	W	G	A	N	F	V	A	V	G	V	D	T	M	L	Y	S	D	A	L	D	Q	R	L	A	M	F	K	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)								S	S										T	T																							T	T