Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP23325
DateThu Jan 5 11:39:22 GMT 2012
Unique Job ID8e718d968eab9992

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template d2ajaa1
Top template information
Fold:alpha-alpha superhelix
Superfamily:Pseudo ankyrin repeat-like
Family:Pseudo ankyrin repeat
Confidence and coverage
Confidence:100.0% Coverage: 37%
269 residues ( 37% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
387 residues ( 53%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MITRIPRSSFSANINNTAQTNEHQTLSELFYKELEDKFSGKELATPLLKSFSENCRQNGR
Secondary structure 
SS confidence 
Disorder  ???????
????????????
Disorder confidence 
 
   .........70.........80.........90.........100.........110.........120
Sequence  HIFSNKDFVIKFSTSVLQADKKEITIINKNENTTLTQTIAPIFEKYLMEILPQRSDTLDK
Secondary structure 
SS confidence 
Disorder 
???????
??
Disorder confidence 
 
   .........130.........140.........150.........160.........170.........180
Sequence  QELNLKSDRKEKEFPRIKLNGQCYFPGRPQNRIVCRHIAAQYINDIYQNVDYKPHQDDYS
Secondary structure 
SS confidence 
Disorder  ??????
??
Disorder confidence 
 
   .........190.........200.........210.........220.........230.........240
Sequence  SAEKFLTHFNKKCKNQTLALVSSRPEGRCVAACGDFGLVMKAYFDKMESNGISVMAAILL
Secondary structure 
SS confidence 
Disorder 
??
?
?
??
???????
?
Disorder confidence 
 
   .........250.........260.........270.........280.........290.........300
Sequence  VDNHALTVRLRIKNTTEGCTHYVVSVYDPNVTNDKIRIMSESKENIKHYSLMDFMNVDYS
Secondary structure 
SS confidence 
Disorder 
?
?
Disorder confidence 
 
   .........310.........320.........330.........340.........350.........360
Sequence  LLKWSNDHVINQSVAIIPALPKEQLLMLKGSVDEITPPLSPATMNLLMAIGQNHQLTQLM
Secondary structure 
SS confidence 
Disorder  ?
???
Disorder confidence 
 
   .........370.........380.........390.........400.........410.........420
Sequence  IQLQKMPELHRTEMLTAYNSINLPGLYLAINYGNADIVETIFNSLSETGYEGLLSKKNLM
Secondary structure 
SS confidence 
Disorder 
??
?
Disorder confidence 
 
   .........430.........440.........450.........460.........470.........480
Sequence  HILEAKDKNGFSGLFLAISRKDKNVVTSILNALPKLAATHHLDNEQVYKFLSAKNRTSSH
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........490.........500.........510.........520.........530.........540
Sequence  VLYHVMANGDADMLKIVLNALPLLIRTCHLTKEQVLDLLKAKDFYGCPGLYLAMQNGHSD
Secondary structure 
SS confidence 
Disorder 
?
Disorder confidence 
 
   .........550.........560.........570.........580.........590.........600
Sequence  IVKVILEALPSLAQEINISASDIVDLLTAKSLARDTGLFMAMQRGHMNVINTIFNALPTL
Secondary structure 
SS confidence 
Disorder 
?
Disorder confidence 
 
   .........610.........620.........630.........640.........650.........660
Sequence  FNTFKFDKKNMKPLLLANNSNEYPGLFSAIQHKQQNVVETVYLALSDHARLFGFTAEDIM
Secondary structure 
SS confidence 
Disorder 
?
?
Disorder confidence 
 
   .........670.........680.........690.........700.........710.........720
Sequence  DFWQHKAPQKYSAFELAFEFGHRVIAELILNTLNKMAESFGFTDNPRYIAEKNYMEALLK
Secondary structure 
SS confidence 
Disorder 
?
?
????
Disorder confidence 
 
   ........
Sequence  KASPHTVR
Secondary structure 
SS confidence 
Disorder 
??????
Disorder confidence 
 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 2aja chain A domain 1

3D model

Region: 354 - 691
Aligned: 269
Modelled: 294
Confidence: 100.0%
Identity: 14%
Fold: alpha-alpha superhelix
Superfamily: Pseudo ankyrin repeat-like
Family: Pseudo ankyrin repeat

Phyre2

PDB 3kea chain B

3D model

Region: 375 - 721
Aligned: 245
Modelled: 247
Confidence: 100.0%
Identity: 20%
PDB header:viral protein
Chain: B: PDB Molecule:k1l;
PDBTitle: structure function studies of vaccinia virus host-range protein k12 reveal a novel ankyrin repeat interaction surface for k1s function

Phyre2

PDB 1n11 chain A

3D model

Region: 383 - 720
Aligned: 278
Modelled: 278
Confidence: 100.0%
Identity: 26%
PDB header:structural protein
Chain: A: PDB Molecule:ankyrin;
PDBTitle: d34 region of human ankyrin-r and linker

Phyre2

PDB 1n11 chain A

3D model

Region: 383 - 720
Aligned: 278
Modelled: 278
Confidence: 100.0%
Identity: 26%
Fold: beta-hairpin-alpha-hairpin repeat
Superfamily: Ankyrin repeat
Family: Ankyrin repeat

Phyre2

PDB 2aja chain A

3D model

Region: 288 - 697
Aligned: 334
Modelled: 363
Confidence: 100.0%
Identity: 13%
PDB header:protein binding
Chain: A: PDB Molecule:ankyrin repeat family protein;
PDBTitle: x-ray structure of an ankyrin repeat family protein q5zsv02 from legionella pneumophila. northeast structural genomics3 consortium target lgr21.

Phyre2

PDB 1s70 chain B

3D model

Region: 386 - 727
Aligned: 275
Modelled: 282
Confidence: 100.0%
Identity: 16%
Fold: beta-hairpin-alpha-hairpin repeat
Superfamily: Ankyrin repeat
Family: Ankyrin repeat

Phyre2

PDB 3ljn chain A

3D model

Region: 379 - 720
Aligned: 264
Modelled: 273
Confidence: 100.0%
Identity: 14%
PDB header:unknown function
Chain: A: PDB Molecule:hypothetical protein;
PDBTitle: ankyrin repeat protein from leishmania major

Phyre2

PDB 2fo1 chain E

3D model

Region: 427 - 720
Aligned: 234
Modelled: 233
Confidence: 100.0%
Identity: 16%
PDB header:gene regulation/signalling protein/dna
Chain: E: PDB Molecule:lin-12 protein;
PDBTitle: crystal structure of the csl-notch-mastermind ternary2 complex bound to dna

Phyre2

PDB 3jxi chain A

3D model

Region: 381 - 693
Aligned: 242
Modelled: 266
Confidence: 100.0%
Identity: 16%
PDB header:membrane protein
Chain: A: PDB Molecule:vanilloid receptor-related osmotically activated channel
PDBTitle: crystal structure of the chicken trpv4 ankyrin repeat domain

Phyre2

PDB 1sw6 chain A

3D model

Region: 433 - 711
Aligned: 205
Modelled: 205
Confidence: 100.0%
Identity: 13%
PDB header:transcription regulation
Chain: A: PDB Molecule:regulatory protein swi6;
PDBTitle: s. cerevisiae swi6 ankyrin-repeat fragment

Phyre2

PDB 1sw6 chain A

3D model

Region: 433 - 711
Aligned: 205
Modelled: 205
Confidence: 100.0%
Identity: 13%
Fold: beta-hairpin-alpha-hairpin repeat
Superfamily: Ankyrin repeat
Family: Ankyrin repeat

Phyre2

PDB 2fo1 chain E domain 1

3D model

Region: 431 - 720
Aligned: 230
Modelled: 230
Confidence: 100.0%
Identity: 16%
Fold: beta-hairpin-alpha-hairpin repeat
Superfamily: Ankyrin repeat
Family: Ankyrin repeat

Phyre2

PDB 2xai chain D

3D model

Region: 478 - 725
Aligned: 216
Modelled: 218
Confidence: 100.0%
Identity: 14%
PDB header:transcription
Chain: D: PDB Molecule:ankyrin repeat and socs box protein 9;
PDBTitle: crystal structure of ankyrin repeat and socs box-containing2 protein 9 (asb9) in complex with elonginb and elonginc

Phyre2

PDB 1wdy chain A

3D model

Region: 429 - 700
Aligned: 228
Modelled: 228
Confidence: 100.0%
Identity: 20%
Fold: beta-hairpin-alpha-hairpin repeat
Superfamily: Ankyrin repeat
Family: Ankyrin repeat

Phyre2

PDB 2f37 chain B

3D model

Region: 378 - 693
Aligned: 244
Modelled: 267
Confidence: 100.0%
Identity: 17%
PDB header:membrane protein
Chain: B: PDB Molecule:transient receptor potential cation channel
PDBTitle: crystal structure of the ankyrin repeat domain of human2 trpv2

Phyre2

PDB 1uoh chain A

3D model

Region: 477 - 720
Aligned: 198
Modelled: 199
Confidence: 99.9%
Identity: 19%
Fold: beta-hairpin-alpha-hairpin repeat
Superfamily: Ankyrin repeat
Family: Ankyrin repeat

Phyre2

PDB 1k1a chain A

3D model

Region: 428 - 720
Aligned: 223
Modelled: 234
Confidence: 99.9%
Identity: 15%
Fold: beta-hairpin-alpha-hairpin repeat
Superfamily: Ankyrin repeat
Family: Ankyrin repeat

Phyre2

PDB 3eu9 chain B

3D model

Region: 475 - 720
Aligned: 202
Modelled: 202
Confidence: 99.9%
Identity: 15%
PDB header:protein binding, methyl-lysine-binding p
Chain: B: PDB Molecule:huntingtin-interacting protein 14;
PDBTitle: the ankyrin repeat domain of huntingtin interacting protein 14

Phyre2

PDB 3ehr chain B

3D model

Region: 489 - 720
Aligned: 179
Modelled: 188
Confidence: 99.9%
Identity: 14%
PDB header:signaling protein
Chain: B: PDB Molecule:osteoclast-stimulating factor 1;
PDBTitle: crystal structure of human osteoclast stimulating factor

Phyre2

PDB 2nyj chain A

3D model

Region: 430 - 694
Aligned: 232
Modelled: 250
Confidence: 99.9%
Identity: 14%
PDB header:transport protein
Chain: A: PDB Molecule:transient receptor potential cation channel
PDBTitle: crystal structure of the ankyrin repeat domain of trpv1

Phyre2
1
d2ajaa1
2
c3keaB_
3
c1n11A_
4
d1n11a_
5
c2ajaA_
6
d1s70b_
7
c3ljnA_
8
c2fo1E_
9
c3jxiA_
10
c1sw6A_
11
d1sw6a_
12
d2fo1e1
13
c2xaiD_
14
d1wdya_
15
c2f37B_
16
d1uoha_
17
d1k1aa_
18
c3eu9B_
19
c3ehrB_
20
c2nyjA_
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90



Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1d2ajaa1
100.0 14 Fold:alpha-alpha superhelix
Superfamily:Pseudo ankyrin repeat-like
Family:Pseudo ankyrin repeat
2c3keaB_
100.0 20 PDB header:viral protein
Chain: B: PDB Molecule:k1l;
PDBTitle: structure function studies of vaccinia virus host-range protein k12 reveal a novel ankyrin repeat interaction surface for k1s function
3c1n11A_
100.0 26 PDB header:structural protein
Chain: A: PDB Molecule:ankyrin;
PDBTitle: d34 region of human ankyrin-r and linker
4d1n11a_
100.0 26 Fold:beta-hairpin-alpha-hairpin repeat
Superfamily:Ankyrin repeat
Family:Ankyrin repeat
5c2ajaA_
100.0 13 PDB header:protein binding
Chain: A: PDB Molecule:ankyrin repeat family protein;
PDBTitle: x-ray structure of an ankyrin repeat family protein q5zsv02 from legionella pneumophila. northeast structural genomics3 consortium target lgr21.
6d1s70b_
100.0 16 Fold:beta-hairpin-alpha-hairpin repeat
Superfamily:Ankyrin repeat
Family:Ankyrin repeat
7c3ljnA_
100.0 14 PDB header:unknown function
Chain: A: PDB Molecule:hypothetical protein;
PDBTitle: ankyrin repeat protein from leishmania major
8c2fo1E_
100.0 16 PDB header:gene regulation/signalling protein/dna
Chain: E: PDB Molecule:lin-12 protein;
PDBTitle: crystal structure of the csl-notch-mastermind ternary2 complex bound to dna
9c3jxiA_
100.0 16 PDB header:membrane protein
Chain: A: PDB Molecule:vanilloid receptor-related osmotically activated channel
PDBTitle: crystal structure of the chicken trpv4 ankyrin repeat domain
10c1sw6A_
100.0 13 PDB header:transcription regulation
Chain: A: PDB Molecule:regulatory protein swi6;
PDBTitle: s. cerevisiae swi6 ankyrin-repeat fragment
11d1sw6a_
100.0 13 Fold:beta-hairpin-alpha-hairpin repeat
Superfamily:Ankyrin repeat
Family:Ankyrin repeat
12d2fo1e1
100.0 16 Fold:beta-hairpin-alpha-hairpin repeat
Superfamily:Ankyrin repeat
Family:Ankyrin repeat
13c2xaiD_
100.0 14 PDB header:transcription
Chain: D: PDB Molecule:ankyrin repeat and socs box protein 9;
PDBTitle: crystal structure of ankyrin repeat and socs box-containing2 protein 9 (asb9) in complex with elonginb and elonginc
14d1wdya_
100.0 20 Fold:beta-hairpin-alpha-hairpin repeat
Superfamily:Ankyrin repeat
Family:Ankyrin repeat
15c2f37B_
100.0 17 PDB header:membrane protein
Chain: B: PDB Molecule:transient receptor potential cation channel
PDBTitle: crystal structure of the ankyrin repeat domain of human2 trpv2
16d1uoha_
99.9 19 Fold:beta-hairpin-alpha-hairpin repeat
Superfamily:Ankyrin repeat
Family:Ankyrin repeat
17d1k1aa_
99.9 15 Fold:beta-hairpin-alpha-hairpin repeat
Superfamily:Ankyrin repeat
Family:Ankyrin repeat
18c3eu9B_
99.9 15 PDB header:protein binding, methyl-lysine-binding p
Chain: B: PDB Molecule:huntingtin-interacting protein 14;
PDBTitle: the ankyrin repeat domain of huntingtin interacting protein 14
19c3ehrB_
99.9 14 PDB header:signaling protein
Chain: B: PDB Molecule:osteoclast-stimulating factor 1;
PDBTitle: crystal structure of human osteoclast stimulating factor
20c2nyjA_
99.9 14 PDB header:transport protein
Chain: A: PDB Molecule:transient receptor potential cation channel
PDBTitle: crystal structure of the ankyrin repeat domain of trpv1
21c3d9hA_
not modelled 99.9 16 PDB header:structural protein, protein binding
Chain: A: PDB Molecule:cdna flj77766, highly similar to homo sapiens
PDBTitle: crystal structure of the splice variant of human asb92 (hasb9-2), an ankyrin repeat protein
22c1ycsB_
not modelled 99.9 15 PDB header:complex (anti-oncogene/ankyrin repeats)
Chain: B: PDB Molecule:53bp2;
PDBTitle: p53-53bp2 complex
23d1ixva_
not modelled 99.9 16 Fold:beta-hairpin-alpha-hairpin repeat
Superfamily:Ankyrin repeat
Family:Ankyrin repeat
24c3b7bB_
not modelled 99.9 17 PDB header:transferase
Chain: B: PDB Molecule:euchromatic histone-lysine n-methyltransferase 1;
PDBTitle: euhmt1 (glp) ankyrin repeat domain (structure 1)
25c2f8xK_
not modelled 99.9 18 PDB header:transcription/dna
Chain: K: PDB Molecule:neurogenic locus notch homolog protein 1;
PDBTitle: crystal structure of activated notch, csl and maml on hes-12 promoter dna sequence
26c2vgeA_
not modelled 99.9 13 PDB header:transcription
Chain: A: PDB Molecule:rela-associated inhibitor;
PDBTitle: crystal structure of the c-terminal region of human iaspp
27c3ui2A_
not modelled 99.9 14 PDB header:transport protein
Chain: A: PDB Molecule:signal recognition particle 43 kda protein, chloroplastic;
PDBTitle: crystal structure of the cpsrp54 tail bound to cpsrp43
28c1oy3D_
not modelled 99.9 19 PDB header:dna binding protein
Chain: D: PDB Molecule:transcription factor inhibitor i-kappa-b-beta;
PDBTitle: crystal structure of an ikbbeta/nf-kb p65 homodimer complex
29d1oy3d_
not modelled 99.9 19 Fold:beta-hairpin-alpha-hairpin repeat
Superfamily:Ankyrin repeat
Family:Ankyrin repeat
30d1iknd_
not modelled 99.9 21 Fold:beta-hairpin-alpha-hairpin repeat
Superfamily:Ankyrin repeat
Family:Ankyrin repeat
31c3t8kB_
not modelled 99.9 10 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:uncharacterized protein;
PDBTitle: the crystal structure of a functionally unknown protein lebu_0176 from2 leptotrichia buccalis c-1013-b
32d1ot8a_
not modelled 99.9 20 Fold:beta-hairpin-alpha-hairpin repeat
Superfamily:Ankyrin repeat
Family:Ankyrin repeat
33c2kbxA_
not modelled 99.9 17 PDB header:cell adhesion
Chain: A: PDB Molecule:integrin-linked protein kinase;
PDBTitle: solution structure of ilk-pinch complex
34c2rfaA_
not modelled 99.9 16 PDB header:membrane protein
Chain: A: PDB Molecule:transient receptor potential cation channel subfamily v
PDBTitle: crystal structure of the mouse trpv6 ankyrin repeat domain
35c3jueA_
not modelled 99.9 14 PDB header:protein transport/endocytosis
Chain: A: PDB Molecule:arfgap with coiled-coil, ank repeat and ph domain-
PDBTitle: crystal structure of arfgap and ank repeat domain of acap1
36c3deoA_
not modelled 99.9 10 PDB header:protein transport, membrane protein
Chain: A: PDB Molecule:signal recognition particle 43 kda protein;
PDBTitle: structural basis for specific substrate recognition by the2 chloroplast signal recognition particle protein cpsrp43
37c2b0oF_
not modelled 99.9 19 PDB header:metal binding protein
Chain: F: PDB Molecule:uplc1;
PDBTitle: crystal structure of uplc1 gap domain
38d1dcqa1
not modelled 99.9 16 Fold:beta-hairpin-alpha-hairpin repeat
Superfamily:Ankyrin repeat
Family:Ankyrin repeat
39c1dcqA_
not modelled 99.8 14 PDB header:metal binding protein
Chain: A: PDB Molecule:pyk2-associated protein beta;
PDBTitle: crystal structure of the arf-gap domain and ankyrin repeats2 of papbeta.
40c3hraA_
not modelled 99.8 15 PDB header:structural protein
Chain: A: PDB Molecule:ankyrin repeat family protein;
PDBTitle: crystal structure of ef0377 an ankyrin repeat protein
41c3lvrE_
not modelled 99.8 15 PDB header:protein transport
Chain: E: PDB Molecule:arf-gap with sh3 domain, ank repeat and ph domain-
PDBTitle: the crystal structure of asap3 in complex with arf6 in transition2 state soaked with calcium
42d2a5ea_
not modelled 99.8 16 Fold:beta-hairpin-alpha-hairpin repeat
Superfamily:Ankyrin repeat
Family:Ankyrin repeat
43c3twtD_
not modelled 99.8 15 PDB header:signaling protein/peptide
Chain: D: PDB Molecule:tankyrase-2;
PDBTitle: crystal structure of arc4 from human tankyrase 2 in complex with2 peptide from human mcl1 (chimeric peptide)
44c2rfmB_
not modelled 99.8 18 PDB header:protein binding
Chain: B: PDB Molecule:putative ankyrin repeat protein tv1425;
PDBTitle: structure of a thermophilic ankyrin repeat protein
45c1ympB_
not modelled 99.8 17 PDB header:transcription
Chain: B: PDB Molecule:notch 1 protein;
PDBTitle: the crystal structure of a partial mouse notch-1 ankyrin2 domain: repeats 4 through 7 preserve an ankyrin fold
46c1ympA_
not modelled 99.8 17 PDB header:transcription
Chain: A: PDB Molecule:notch 1 protein;
PDBTitle: the crystal structure of a partial mouse notch-1 ankyrin2 domain: repeats 4 through 7 preserve an ankyrin fold
47d1blxb_
not modelled 99.8 15 Fold:beta-hairpin-alpha-hairpin repeat
Superfamily:Ankyrin repeat
Family:Ankyrin repeat
48c2v5qC_
not modelled 99.8 21 PDB header:transferase
Chain: C: PDB Molecule:design ankyrin repeat protein;
PDBTitle: crystal structure of wild-type plk-1 kinase domain in2 complex with a selective darpin
49c3c5rB_
not modelled 99.8 20 PDB header:protein binding
Chain: B: PDB Molecule:brca1-associated ring domain protein 1;
PDBTitle: crystal structure of the bard1 ankyrin repeat domain and its2 functional consequences
50d1ycsb1
not modelled 99.8 15 Fold:beta-hairpin-alpha-hairpin repeat
Superfamily:Ankyrin repeat
Family:Ankyrin repeat
51c2jabC_
not modelled 99.8 20 PDB header:de novo protein
Chain: C: PDB Molecule:h10-2-g3;
PDBTitle: a designed ankyrin repeat protein evolved to picomolar2 affinity to her2
52d1myoa_
not modelled 99.8 16 Fold:beta-hairpin-alpha-hairpin repeat
Superfamily:Ankyrin repeat
Family:Ankyrin repeat
53d1ihba_
not modelled 99.8 17 Fold:beta-hairpin-alpha-hairpin repeat
Superfamily:Ankyrin repeat
Family:Ankyrin repeat
54d1bi7b_
not modelled 99.7 17 Fold:beta-hairpin-alpha-hairpin repeat
Superfamily:Ankyrin repeat
Family:Ankyrin repeat
55d1awcb_
not modelled 99.7 22 Fold:beta-hairpin-alpha-hairpin repeat
Superfamily:Ankyrin repeat
Family:Ankyrin repeat
56c2l6bA_
not modelled 99.7 18 PDB header:de novo protein
Chain: A: PDB Molecule:nr1c;
PDBTitle: nrc consensus ankyrin repeat protein solution structure
57d1bd8a_
not modelled 99.7 15 Fold:beta-hairpin-alpha-hairpin repeat
Superfamily:Ankyrin repeat
Family:Ankyrin repeat
58c2zgdA_
not modelled 99.7 27 PDB header:de novo protein
Chain: A: PDB Molecule:3 repeat synthetic ankyrin;
PDBTitle: asn-hydroxylation stabilises the ankyrin repeat domain fold
59c1n0qB_
not modelled 99.7 26 PDB header:structural protein
Chain: B: PDB Molecule:3 ankyrin repeats;
PDBTitle: 3ank: a designed ankyrin repeat protein with three identical consensus2 repeats
60c1n0rA_
not modelled 99.7 24 PDB header:structural protein
Chain: A: PDB Molecule:4 ankyrin repeats;
PDBTitle: 4ank: a designed ankyrin repeat protein with four identical2 consensus repeats
61c2xenA_
not modelled 99.6 20 PDB header:de novo protein
Chain: A: PDB Molecule:ni1c mut4;
PDBTitle: structural determinants for improved thermal stability of2 designed ankyrin repeat proteins with a redesigned c-3 capping module.
62c2xumS_
not modelled 77.1 11 PDB header:oxidoreductase/peptide
Chain: S: PDB Molecule:asp-substrate peptide 2;
PDBTitle: factor inhibiting hif (fih) q239h mutant in complex with zn(ii), nog2 and asp-substrate peptide (20-mer)
63c3zrhA_
not modelled 60.3 14 PDB header:hydrolase
Chain: A: PDB Molecule:ubiquitin thioesterase zranb1;
PDBTitle: crystal structure of the lys29, lys33-linkage-specific trabid otu2 deubiquitinase domain reveals an ankyrin-repeat ubiquitin binding3 domain (ankubd)
64c1iicA_
not modelled 30.0 10 PDB header:transferase
Chain: A: PDB Molecule:peptide n-myristoyltransferase;
PDBTitle: crystal structure of saccharomyces cerevisiae n-myristoyltransferase2 with bound myristoylcoa
65c2p6fA_
not modelled 29.1 10 PDB header:transferase
Chain: A: PDB Molecule:glycylpeptide n-tetradecanoyltransferase;
PDBTitle: crystal structures of saccharomyces cerevisiae n-myristoyltransferase2 with bound myristoyl-coa and inhibitors
66c2y0iS_
not modelled 26.4 17 PDB header:oxidoreductase/peptide
Chain: S: PDB Molecule:tankyrase-2;
PDBTitle: factor inhibiting hif-1 alpha in complex with tankyrase-2 (tnks2)2 fragment peptide (21-mer)
67c3i08D_
not modelled 25.2 19 PDB header:signaling protein
Chain: D: PDB Molecule:neurogenic locus notch homolog protein 1;
PDBTitle: crystal structure of the s1-cleaved notch1 negative2 regulatory region (nrr)
68c3iu2B_
not modelled 24.5 12 PDB header:transferase
Chain: B: PDB Molecule:glycylpeptide n-tetradecanoyltransferase 1;
PDBTitle: crystal structure of human type-i n-myristoyltransferase with bound2 myristoyl-coa and inhibitor ddd90096
69c1rxtB_
not modelled 23.6 8 PDB header:transferase
Chain: B: PDB Molecule:glycylpeptide n-tetradecanoyltransferase 1;
PDBTitle: crystal structure of human myristoyl-coa:protein n-2 myristoyltransferase.
70c2oo4B_
not modelled 23.3 15 PDB header:cell cycle,signaling protein
Chain: B: PDB Molecule:neurogenic locus notch homolog protein 2;
PDBTitle: structure of lnr-hd (negative regulatory region) from human notch 2
71d1iyka1
not modelled 9.4 23 Fold:Acyl-CoA N-acyltransferases (Nat)
Superfamily:Acyl-CoA N-acyltransferases (Nat)
Family:N-myristoyl transferase, NMT
72c3ix1B_
not modelled 9.0 19 PDB header:biosynthetic protein
Chain: B: PDB Molecule:n-formyl-4-amino-5-aminomethyl-2-methylpyrimidine binding
PDBTitle: periplasmic n-formyl-4-amino-5-aminomethyl-2-methylpyrimidine binding2 protein from bacillus halodurans
73c3ix1A_
not modelled 9.0 19 PDB header:biosynthetic protein
Chain: A: PDB Molecule:n-formyl-4-amino-5-aminomethyl-2-methylpyrimidine binding
PDBTitle: periplasmic n-formyl-4-amino-5-aminomethyl-2-methylpyrimidine binding2 protein from bacillus halodurans
74c3mkqB_
not modelled 9.0 21 PDB header:transport protein
Chain: B: PDB Molecule:coatomer subunit alpha;
PDBTitle: crystal structure of yeast alpha/betaprime-cop subcomplex of the copi2 vesicular coat
75d1iica1
not modelled 9.0 15 Fold:Acyl-CoA N-acyltransferases (Nat)
Superfamily:Acyl-CoA N-acyltransferases (Nat)
Family:N-myristoyl transferase, NMT
76d2bosa_
not modelled 8.7 57 Fold:OB-fold
Superfamily:Bacterial enterotoxins
Family:Bacterial AB5 toxins, B-subunits
77c1ponB_
not modelled 8.4 31 PDB header:calcium-binding protein
Chain: B: PDB Molecule:troponin c;
PDBTitle: site iii-site iv troponin c heterodimer, nmr
78c1iylC_
not modelled 8.3 23 PDB header:transferase
Chain: C: PDB Molecule:myristoyl-coa:protein n-myristoyltransferase;
PDBTitle: crystal structure of candida albicans n-myristoyltransferase with non-2 peptidic inhibitor
79d1rxta1
not modelled 7.7 19 Fold:Acyl-CoA N-acyltransferases (Nat)
Superfamily:Acyl-CoA N-acyltransferases (Nat)
Family:N-myristoyl transferase, NMT
80c2be6F_
not modelled 7.2 28 PDB header:membrane protein
Chain: F: PDB Molecule:voltage-dependent l-type calcium channel alpha-1c subunit;
PDBTitle: 2.0 a crystal structure of the cav1.2 iq domain-ca/cam complex
81d2qamc2
not modelled 7.0 50 Fold:OB-fold
Superfamily:Nucleic acid-binding proteins
Family:Cold shock DNA-binding domain-like
82c2jq5A_
not modelled 6.8 38 PDB header:structural genomics
Chain: A: PDB Molecule:sec-c motif;
PDBTitle: solution structure of rpa3114, a sec-c motif containing2 protein from rhodopseudomonas palustris; northeast3 structural genomics consortium target rpt5 / ontario4 center for structural proteomics target rp3097
83c2wuuA_
not modelled 6.8 19 PDB header:transferase
Chain: A: PDB Molecule:n-myristoyltransferase;
PDBTitle: structure of n-myristoyltransferase from l. donovani
84d1rl2a2
not modelled 6.7 57 Fold:OB-fold
Superfamily:Nucleic acid-binding proteins
Family:Cold shock DNA-binding domain-like
85d1ukfa_
not modelled 6.6 43 Fold:Cysteine proteinases
Superfamily:Cysteine proteinases
Family:Avirulence protein Avrpph3
86d2i9wa1
not modelled 6.4 38 Fold:Cystatin-like
Superfamily:NTF2-like
Family:SEC-C associated NTF2-like domain
87c3e4fB_
not modelled 5.9 15 PDB header:transferase
Chain: B: PDB Molecule:aminoglycoside n3-acetyltransferase;
PDBTitle: crystal structure of ba2930- a putative aminoglycoside n3-2 acetyltransferase from bacillus anthracis
88d1v47a2
not modelled 5.5 53 Fold:Adenine nucleotide alpha hydrolase-like
Superfamily:Nucleotidylyl transferase
Family:ATP sulfurylase catalytic domain
89c2khsB_
not modelled 5.4 28 PDB header:hydrolase
Chain: B: PDB Molecule:nuclease;
PDBTitle: solution structure of snase121:snase(111-143) complex
90c2i9wA_
not modelled 5.3 38 PDB header:metal binding protein
Chain: A: PDB Molecule:hypothetical protein;
PDBTitle: crystal structure of a sec-c motif containing protein (psyc_2064) from2 psychrobacter arcticus at 1.75 a resolution

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0