Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP30139
DateThu Jan 5 11:46:05 GMT 2012
Unique Job ID76f32b7e341fa5a3

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template d1xm3a_
Top template information
Fold:TIM beta/alpha-barrel
Superfamily:ThiG-like
Family:ThiG-like
Confidence and coverage
Confidence:100.0% Coverage: 95%
242 residues ( 95% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MLRIADKTFDSHLFTGTGKFASSQLMVEAIRASGSQLVTLAMKRVDLRQHNDAILEPLIA
Secondary structure 
SS confidence 
Disorder  ?
??
??
???
Disorder confidence 
 
   .........70.........80.........90.........100.........110.........120
Sequence  AGVTLLPNTSGAKTAEEAIFAAHLAREALGTNWLKLEIHPDARWLLPDPIETLKAAETLV
Secondary structure 
SS confidence 
Disorder 
?
Disorder confidence 
 
   .........130.........140.........150.........160.........170.........180
Sequence  QQGFVVLPYCGADPVLCKRLEEVGCAAVMPLGAPIGSNQGLETRAMLEIIIQQATVPVVV
Secondary structure 
SS confidence 
Disorder 
??
Disorder confidence 
 
   .........190.........200.........210.........220.........230.........240
Sequence  DAGIGVPSHAAQALEMGADAVLVNTAIAVADDPVNMAKAFRLAVEAGLLARQSGPGSRSY
Secondary structure 
SS confidence 
Disorder 
??
?
???
??????
Disorder confidence 
 
   .........250......
Sequence  FAHATSPLTGFLEASA
Secondary structure 
SS confidence 
Disorder  ????????????????
Disorder confidence 
 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1xm3 chain A

3D model

Region: 2 - 249
Aligned: 242
Modelled: 248
Confidence: 100.0%
Identity: 49%
Fold: TIM beta/alpha-barrel
Superfamily: ThiG-like
Family: ThiG-like

Phyre2

PDB 2htm chain B

3D model

Region: 2 - 238
Aligned: 228
Modelled: 237
Confidence: 100.0%
Identity: 54%
PDB header:biosynthetic protein
Chain: B: PDB Molecule:thiazole biosynthesis protein thig;
PDBTitle: crystal structure of ttha0676 from thermus thermophilus hb8

Phyre2

PDB 1wv2 chain A

3D model

Region: 2 - 239
Aligned: 227
Modelled: 238
Confidence: 100.0%
Identity: 48%
Fold: TIM beta/alpha-barrel
Superfamily: ThiG-like
Family: ThiG-like

Phyre2

PDB 1vhn chain A

3D model

Region: 12 - 218
Aligned: 200
Modelled: 205
Confidence: 100.0%
Identity: 19%
Fold: TIM beta/alpha-barrel
Superfamily: FMN-linked oxidoreductases
Family: FMN-linked oxidoreductases

Phyre2

PDB 3b0v chain D

3D model

Region: 8 - 214
Aligned: 202
Modelled: 204
Confidence: 99.9%
Identity: 18%
PDB header:oxidoreductase/rna
Chain: D: PDB Molecule:trna-dihydrouridine synthase;
PDBTitle: trna-dihydrouridine synthase from thermus thermophilus in complex with2 trna

Phyre2

PDB 1jub chain A

3D model

Region: 3 - 225
Aligned: 222
Modelled: 222
Confidence: 99.9%
Identity: 18%
Fold: TIM beta/alpha-barrel
Superfamily: FMN-linked oxidoreductases
Family: FMN-linked oxidoreductases

Phyre2

PDB 2gjl chain A

3D model

Region: 9 - 226
Aligned: 205
Modelled: 207
Confidence: 99.9%
Identity: 16%
PDB header:oxidoreductase
Chain: A: PDB Molecule:hypothetical protein pa1024;
PDBTitle: crystal structure of 2-nitropropane dioxygenase

Phyre2

PDB 2z6j chain B

3D model

Region: 7 - 212
Aligned: 190
Modelled: 206
Confidence: 99.9%
Identity: 23%
PDB header:oxidoreductase
Chain: B: PDB Molecule:trans-2-enoyl-acp reductase ii;
PDBTitle: crystal structure of s. pneumoniae enoyl-acyl carrier2 protein reductase (fabk) in complex with an inhibitor

Phyre2

PDB 1ep3 chain A

3D model

Region: 3 - 225
Aligned: 222
Modelled: 223
Confidence: 99.9%
Identity: 15%
Fold: TIM beta/alpha-barrel
Superfamily: FMN-linked oxidoreductases
Family: FMN-linked oxidoreductases

Phyre2

PDB 1d3g chain A

3D model

Region: 3 - 226
Aligned: 223
Modelled: 223
Confidence: 99.9%
Identity: 17%
Fold: TIM beta/alpha-barrel
Superfamily: FMN-linked oxidoreductases
Family: FMN-linked oxidoreductases

Phyre2

PDB 1gte chain A domain 2

3D model

Region: 3 - 225
Aligned: 222
Modelled: 223
Confidence: 99.9%
Identity: 17%
Fold: TIM beta/alpha-barrel
Superfamily: FMN-linked oxidoreductases
Family: FMN-linked oxidoreductases

Phyre2

PDB 1f76 chain A

3D model

Region: 2 - 222
Aligned: 219
Modelled: 221
Confidence: 99.9%
Identity: 16%
Fold: TIM beta/alpha-barrel
Superfamily: FMN-linked oxidoreductases
Family: FMN-linked oxidoreductases

Phyre2

PDB 3bo9 chain B

3D model

Region: 9 - 212
Aligned: 188
Modelled: 193
Confidence: 99.9%
Identity: 19%
PDB header:oxidoreductase
Chain: B: PDB Molecule:putative nitroalkan dioxygenase;
PDBTitle: crystal structure of putative nitroalkan dioxygenase (tm0800) from2 thermotoga maritima at 2.71 a resolution

Phyre2

PDB 1gth chain D

3D model

Region: 3 - 209
Aligned: 206
Modelled: 207
Confidence: 99.9%
Identity: 18%
PDB header:oxidoreductase
Chain: D: PDB Molecule:dihydropyrimidine dehydrogenase;
PDBTitle: dihydropyrimidine dehydrogenase (dpd) from pig, ternary2 complex with nadph and 5-iodouracil

Phyre2

PDB 1p0k chain A

3D model

Region: 3 - 210
Aligned: 203
Modelled: 208
Confidence: 99.9%
Identity: 19%
Fold: TIM beta/alpha-barrel
Superfamily: FMN-linked oxidoreductases
Family: FMN-linked oxidoreductases

Phyre2

PDB 1ypf chain B

3D model

Region: 3 - 210
Aligned: 198
Modelled: 208
Confidence: 99.9%
Identity: 19%
PDB header:oxidoreductase
Chain: B: PDB Molecule:gmp reductase;
PDBTitle: crystal structure of guac (ba5705) from bacillus anthracis at 1.8 a2 resolution

Phyre2

PDB 1tb3 chain A domain 1

3D model

Region: 3 - 208
Aligned: 197
Modelled: 200
Confidence: 99.9%
Identity: 13%
Fold: TIM beta/alpha-barrel
Superfamily: FMN-linked oxidoreductases
Family: FMN-linked oxidoreductases

Phyre2

PDB 2fpt chain A

3D model

Region: 3 - 226
Aligned: 223
Modelled: 223
Confidence: 99.9%
Identity: 14%
PDB header:oxidoreductase
Chain: A: PDB Molecule:dihydroorotate dehydrogenase, mitochondrial;
PDBTitle: dual binding mode of a novel series of dhodh inhibitors

Phyre2

PDB 1gox chain A

3D model

Region: 2 - 208
Aligned: 197
Modelled: 207
Confidence: 99.9%
Identity: 14%
Fold: TIM beta/alpha-barrel
Superfamily: FMN-linked oxidoreductases
Family: FMN-linked oxidoreductases

Phyre2

PDB 3khj chain E

3D model

Region: 3 - 211
Aligned: 196
Modelled: 209
Confidence: 99.9%
Identity: 17%
PDB header:oxidoreductase
Chain: E: PDB Molecule:inosine-5-monophosphate dehydrogenase;
PDBTitle: c. parvum inosine monophosphate dehydrogenase bound by inhibitor c64

Phyre2
1
d1xm3a_
2
c2htmB_
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d1wv2a_
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d1vhna_
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c3b0vD_
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d1juba_
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c2gjlA_
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c2z6jB_
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d1ep3a_
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d1d3ga_
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d1gtea2
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d1f76a_
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c3bo9B_
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c1gthD_
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d1p0ka_
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c1ypfB_
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d1tb3a1
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c2fptA_
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d1goxa_
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c3khjE_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1d1xm3a_
100.0 49 Fold:TIM beta/alpha-barrel
Superfamily:ThiG-like
Family:ThiG-like
2c2htmB_
100.0 54 PDB header:biosynthetic protein
Chain: B: PDB Molecule:thiazole biosynthesis protein thig;
PDBTitle: crystal structure of ttha0676 from thermus thermophilus hb8
3d1wv2a_
100.0 48 Fold:TIM beta/alpha-barrel
Superfamily:ThiG-like
Family:ThiG-like
4d1vhna_
100.0 19 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
5c3b0vD_
99.9 18 PDB header:oxidoreductase/rna
Chain: D: PDB Molecule:trna-dihydrouridine synthase;
PDBTitle: trna-dihydrouridine synthase from thermus thermophilus in complex with2 trna
6d1juba_
99.9 18 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
7c2gjlA_
99.9 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:hypothetical protein pa1024;
PDBTitle: crystal structure of 2-nitropropane dioxygenase
8c2z6jB_
99.9 23 PDB header:oxidoreductase
Chain: B: PDB Molecule:trans-2-enoyl-acp reductase ii;
PDBTitle: crystal structure of s. pneumoniae enoyl-acyl carrier2 protein reductase (fabk) in complex with an inhibitor
9d1ep3a_
99.9 15 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
10d1d3ga_
99.9 17 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
11d1gtea2
99.9 17 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
12d1f76a_
99.9 16 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
13c3bo9B_
99.9 19 PDB header:oxidoreductase
Chain: B: PDB Molecule:putative nitroalkan dioxygenase;
PDBTitle: crystal structure of putative nitroalkan dioxygenase (tm0800) from2 thermotoga maritima at 2.71 a resolution
14c1gthD_
99.9 18 PDB header:oxidoreductase
Chain: D: PDB Molecule:dihydropyrimidine dehydrogenase;
PDBTitle: dihydropyrimidine dehydrogenase (dpd) from pig, ternary2 complex with nadph and 5-iodouracil
15d1p0ka_
99.9 19 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
16c1ypfB_
99.9 19 PDB header:oxidoreductase
Chain: B: PDB Molecule:gmp reductase;
PDBTitle: crystal structure of guac (ba5705) from bacillus anthracis at 1.8 a2 resolution
17d1tb3a1
99.9 13 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
18c2fptA_
99.9 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:dihydroorotate dehydrogenase, mitochondrial;
PDBTitle: dual binding mode of a novel series of dhodh inhibitors
19d1goxa_
99.9 14 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
20c3khjE_
99.9 17 PDB header:oxidoreductase
Chain: E: PDB Molecule:inosine-5-monophosphate dehydrogenase;
PDBTitle: c. parvum inosine monophosphate dehydrogenase bound by inhibitor c64
21d2b4ga1
not modelled 99.9 16 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
22d1p4ca_
not modelled 99.9 20 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
23c2zrvC_
not modelled 99.9 15 PDB header:isomerase
Chain: C: PDB Molecule:isopentenyl-diphosphate delta-isomerase;
PDBTitle: crystal structure of sulfolobus shibatae isopentenyl2 diphosphate isomerase in complex with reduced fmn.
24c3bw2A_
not modelled 99.9 24 PDB header:oxidoreductase
Chain: A: PDB Molecule:2-nitropropane dioxygenase;
PDBTitle: crystal structures and site-directed mutagenesis study of nitroalkane2 oxidase from streptomyces ansochromogenes
25d1uuma_
not modelled 99.9 19 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
26c1tv5A_
not modelled 99.9 11 PDB header:oxidoreductase
Chain: A: PDB Molecule:dihydroorotate dehydrogenase homolog, mitochondrial;
PDBTitle: plasmodium falciparum dihydroorotate dehydrogenase with a bound2 inhibitor
27d1tv5a1
not modelled 99.9 11 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
28c2a7nA_
not modelled 99.9 20 PDB header:oxidoreductase
Chain: A: PDB Molecule:l(+)-mandelate dehydrogenase;
PDBTitle: crystal structure of the g81a mutant of the active chimera of (s)-2 mandelate dehydrogenase
29c2e77B_
not modelled 99.9 14 PDB header:oxidoreductase
Chain: B: PDB Molecule:lactate oxidase;
PDBTitle: crystal structure of l-lactate oxidase with pyruvate complex
30c3r2gA_
not modelled 99.9 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:inosine 5'-monophosphate dehydrogenase;
PDBTitle: crystal structure of inosine 5' monophosphate dehydrogenase from2 legionella pneumophila
31c2rduA_
not modelled 99.9 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:hydroxyacid oxidase 1;
PDBTitle: crystal structure of human glycolate oxidase in complex with2 glyoxylate
32d1pvna1
not modelled 99.9 14 Fold:TIM beta/alpha-barrel
Superfamily:Inosine monophosphate dehydrogenase (IMPDH)
Family:Inosine monophosphate dehydrogenase (IMPDH)
33c3gr7A_
not modelled 99.9 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:nadph dehydrogenase;
PDBTitle: structure of oye from geobacillus kaustophilus, hexagonal2 crystal form
34d1kbia1
not modelled 99.9 11 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
35d1eepa_
not modelled 99.9 13 Fold:TIM beta/alpha-barrel
Superfamily:Inosine monophosphate dehydrogenase (IMPDH)
Family:Inosine monophosphate dehydrogenase (IMPDH)
36c3oixA_
not modelled 99.9 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative dihydroorotate dehydrogenase; dihydroorotate
PDBTitle: crystal structure of the putative dihydroorotate dehydrogenase from2 streptococcus mutans
37d1vc4a_
not modelled 99.9 18 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
38c2cdh1_
not modelled 99.9 14 PDB header:transferase
Chain: 1: PDB Molecule:enoyl reductase;
PDBTitle: architecture of the thermomyces lanuginosus fungal fatty2 acid synthase at 5 angstrom resolution.
39c1kbiB_
not modelled 99.9 12 PDB header:oxidoreductase
Chain: B: PDB Molecule:cytochrome b2;
PDBTitle: crystallographic study of the recombinant flavin-binding domain of2 baker's yeast flavocytochrome b2: comparison with the intact wild-3 type enzyme
40c3qjaA_
not modelled 99.9 14 PDB header:lyase
Chain: A: PDB Molecule:indole-3-glycerol phosphate synthase;
PDBTitle: crystal structure of the mycobacterium tuberculosis indole-3-glycerol2 phosphate synthase (trpc) in apo form
41d1vrda1
not modelled 99.9 17 Fold:TIM beta/alpha-barrel
Superfamily:Inosine monophosphate dehydrogenase (IMPDH)
Family:Inosine monophosphate dehydrogenase (IMPDH)
42d1jr1a1
not modelled 99.9 17 Fold:TIM beta/alpha-barrel
Superfamily:Inosine monophosphate dehydrogenase (IMPDH)
Family:Inosine monophosphate dehydrogenase (IMPDH)
43c3ffsC_
not modelled 99.9 17 PDB header:oxidoreductase
Chain: C: PDB Molecule:inosine-5-monophosphate dehydrogenase;
PDBTitle: the crystal structure of cryptosporidium parvum inosine-5'-2 monophosphate dehydrogenase
44d1zfja1
not modelled 99.9 15 Fold:TIM beta/alpha-barrel
Superfamily:Inosine monophosphate dehydrogenase (IMPDH)
Family:Inosine monophosphate dehydrogenase (IMPDH)
45d1vcfa1
not modelled 99.9 19 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
46d1i4na_
not modelled 99.9 14 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
47d1a53a_
not modelled 99.9 11 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
48c2a7rD_
not modelled 99.9 12 PDB header:oxidoreductase
Chain: D: PDB Molecule:gmp reductase 2;
PDBTitle: crystal structure of human guanosine monophosphate2 reductase 2 (gmpr2)
49d1jcna1
not modelled 99.9 15 Fold:TIM beta/alpha-barrel
Superfamily:Inosine monophosphate dehydrogenase (IMPDH)
Family:Inosine monophosphate dehydrogenase (IMPDH)
50c1vrdA_
not modelled 99.9 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:inosine-5'-monophosphate dehydrogenase;
PDBTitle: crystal structure of inosine-5'-monophosphate dehydrogenase (tm1347)2 from thermotoga maritima at 2.18 a resolution
51d1piia2
not modelled 99.9 12 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
52c1piiA_
not modelled 99.9 12 PDB header:bifunctional(isomerase and synthase)
Chain: A: PDB Molecule:n-(5'phosphoribosyl)anthranilate isomerase;
PDBTitle: three-dimensional structure of the bifunctional enzyme2 phosphoribosylanthranilate isomerase:3 indoleglycerolphosphate synthase from escherichia coli4 refined at 2.0 angstroms resolution
53c1me9A_
not modelled 99.9 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:inosine-5'-monophosphate dehydrogenase;
PDBTitle: inosine monophosphate dehydrogenase (impdh) from2 tritrichomonas foetus with imp bound
54d1yxya1
not modelled 99.9 14 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:NanE-like
55c2h90A_
not modelled 99.8 24 PDB header:oxidoreductase
Chain: A: PDB Molecule:xenobiotic reductase a;
PDBTitle: xenobiotic reductase a in complex with coumarin
56c3gyeA_
not modelled 99.8 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:dihydroorotate dehydrogenase, putative;
PDBTitle: didydroorotate dehydrogenase from leishmania major
57d1y0ea_
not modelled 99.8 13 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:NanE-like
58d2cu0a1
not modelled 99.8 17 Fold:TIM beta/alpha-barrel
Superfamily:Inosine monophosphate dehydrogenase (IMPDH)
Family:Inosine monophosphate dehydrogenase (IMPDH)
59c3hf3A_
not modelled 99.8 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:chromate reductase;
PDBTitle: old yellow enzyme from thermus scotoductus sa-01
60c2qr6A_
not modelled 99.8 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:imp dehydrogenase/gmp reductase;
PDBTitle: crystal structure of imp dehydrogenase/gmp reductase-like protein2 (np_599840.1) from corynebacterium glutamicum atcc 13032 kitasato at3 1.50 a resolution
61c1jcnA_
not modelled 99.8 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:inosine monophosphate dehydrogenase i;
PDBTitle: binary complex of human type-i inosine monophosphate dehydrogenase2 with 6-cl-imp
62d1z41a1
not modelled 99.8 19 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
63c3igsB_
not modelled 99.8 16 PDB header:isomerase
Chain: B: PDB Molecule:n-acetylmannosamine-6-phosphate 2-epimerase 2;
PDBTitle: structure of the salmonella enterica n-acetylmannosamine-6-phosphate2 2-epimerase
64d1ps9a1
not modelled 99.8 18 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
65c1ps9A_
not modelled 99.8 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:2,4-dienoyl-coa reductase;
PDBTitle: the crystal structure and reaction mechanism of e. coli 2,4-2 dienoyl coa reductase
66c3q58A_
not modelled 99.8 16 PDB header:isomerase
Chain: A: PDB Molecule:n-acetylmannosamine-6-phosphate 2-epimerase;
PDBTitle: structure of n-acetylmannosamine-6-phosphate epimerase from salmonella2 enterica
67c2cu0B_
not modelled 99.8 18 PDB header:oxidoreductase
Chain: B: PDB Molecule:inosine-5'-monophosphate dehydrogenase;
PDBTitle: crystal structure of inosine-5'-monophosphate dehydrogenase from2 pyrococcus horikoshii ot3
68c2c3zA_
not modelled 99.8 11 PDB header:lyase
Chain: A: PDB Molecule:indole-3-glycerol phosphate synthase;
PDBTitle: crystal structure of a truncated variant of indole-3-2 glycerol phosphate synthase from sulfolobus solfataricus
69d1znna1
not modelled 99.8 18 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:PdxS-like
70c1znnF_
not modelled 99.8 18 PDB header:biosynthetic protein
Chain: F: PDB Molecule:plp synthase;
PDBTitle: structure of the synthase subunit of plp synthase
71c3kruC_
not modelled 99.8 18 PDB header:oxidoreductase
Chain: C: PDB Molecule:nadh:flavin oxidoreductase/nadh oxidase;
PDBTitle: crystal structure of the thermostable old yellow enzyme from2 thermoanaerobacter pseudethanolicus e39
72d1j5ta_
not modelled 99.8 15 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
73d1djqa1
not modelled 99.8 18 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
74c1djnB_
not modelled 99.8 15 PDB header:oxidoreductase
Chain: B: PDB Molecule:trimethylamine dehydrogenase;
PDBTitle: structural and biochemical characterization of recombinant wild type2 trimethylamine dehydrogenase from methylophilus methylotrophus (sp.3 w3a1)
75c2yzrB_
not modelled 99.8 21 PDB header:lyase
Chain: B: PDB Molecule:pyridoxal biosynthesis lyase pdxs;
PDBTitle: crystal structure of pyridoxine biosynthesis protein from2 methanocaldococcus jannaschii
76d1gwja_
not modelled 99.8 15 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
77d1vyra_
not modelled 99.7 14 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
78c3k30B_
not modelled 99.7 15 PDB header:oxidoreductase
Chain: B: PDB Molecule:histamine dehydrogenase;
PDBTitle: histamine dehydrogenase from nocardiodes simplex
79c1zfjA_
not modelled 99.7 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:inosine monophosphate dehydrogenase;
PDBTitle: inosine monophosphate dehydrogenase (impdh; ec 1.1.1.205) from2 streptococcus pyogenes
80d1geqa_
not modelled 99.7 17 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
81d1qopa_
not modelled 99.7 23 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
82c3gkaB_
not modelled 99.7 18 PDB header:oxidoreductase
Chain: B: PDB Molecule:n-ethylmaleimide reductase;
PDBTitle: crystal structure of n-ethylmaleimidine reductase from2 burkholderia pseudomallei
83d1ka9f_
not modelled 99.7 15 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Histidine biosynthesis enzymes
84c2gq8A_
not modelled 99.7 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:oxidoreductase, fmn-binding;
PDBTitle: structure of sye1, an oye homologue from s. ondeidensis, in complex2 with p-hydroxyacetophenone
85d1h5ya_
not modelled 99.7 17 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Histidine biosynthesis enzymes
86d1thfd_
not modelled 99.7 16 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Histidine biosynthesis enzymes
87c3atyA_
not modelled 99.7 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:prostaglandin f2a synthase;
PDBTitle: crystal structure of tcoye
88d1w0ma_
not modelled 99.7 19 Fold:TIM beta/alpha-barrel
Superfamily:Triosephosphate isomerase (TIM)
Family:Triosephosphate isomerase (TIM)
89d1rd5a_
not modelled 99.6 24 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
90c2y85D_
not modelled 99.6 16 PDB header:isomerase
Chain: D: PDB Molecule:phosphoribosyl isomerase a;
PDBTitle: crystal structure of mycobacterium tuberculosis phosphoribosyl2 isomerase with bound rcdrp
91c1yadD_
not modelled 99.6 14 PDB header:transcription
Chain: D: PDB Molecule:regulatory protein teni;
PDBTitle: structure of teni from bacillus subtilis
92d1xi3a_
not modelled 99.6 16 Fold:TIM beta/alpha-barrel
Superfamily:Thiamin phosphate synthase
Family:Thiamin phosphate synthase
93d1vjia_
not modelled 99.6 13 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
94c3f4wA_
not modelled 99.6 14 PDB header:synthase, lyase
Chain: A: PDB Molecule:putative hexulose 6 phosphate synthase;
PDBTitle: the 1.65a crystal structure of 3-hexulose-6-phosphate2 synthase from salmonella typhimurium
95c3ajxA_
not modelled 99.6 15 PDB header:lyase
Chain: A: PDB Molecule:3-hexulose-6-phosphate synthase;
PDBTitle: crystal structure of 3-hexulose-6-phosphate synthase
96c3o63B_
not modelled 99.6 22 PDB header:transferase
Chain: B: PDB Molecule:probable thiamine-phosphate pyrophosphorylase;
PDBTitle: crystal structure of thiamin phosphate synthase from mycobacterium2 tuberculosis
97d1icpa_
not modelled 99.6 15 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
98c2v82A_
not modelled 99.6 18 PDB header:lyase
Chain: A: PDB Molecule:2-dehydro-3-deoxy-6-phosphogalactonate aldolase;
PDBTitle: kdpgal complexed to kdpgal
99c3nm3D_
not modelled 99.6 16 PDB header:transferase
Chain: D: PDB Molecule:thiamine biosynthetic bifunctional enzyme;
PDBTitle: the crystal structure of candida glabrata thi6, a bifunctional enzyme2 involved in thiamin biosyhthesis of eukaryotes
100d1xcfa_
not modelled 99.6 15 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
101d2tpsa_
not modelled 99.6 21 Fold:TIM beta/alpha-barrel
Superfamily:Thiamin phosphate synthase
Family:Thiamin phosphate synthase
102d1wa3a1
not modelled 99.6 17 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
103d1oyaa_
not modelled 99.5 13 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
104c3qc3B_
not modelled 99.5 14 PDB header:isomerase
Chain: B: PDB Molecule:d-ribulose-5-phosphate-3-epimerase;
PDBTitle: crystal structure of a d-ribulose-5-phosphate-3-epimerase (np_954699)2 from homo sapiens at 2.20 a resolution
105c3tdmD_
not modelled 99.5 20 PDB header:de novo protein
Chain: D: PDB Molecule:computationally designed two-fold symmetric tim-barrel
PDBTitle: computationally designed tim-barrel protein, halfflr
106c3navB_
not modelled 99.5 23 PDB header:lyase
Chain: B: PDB Molecule:tryptophan synthase alpha chain;
PDBTitle: crystal structure of an alpha subunit of tryptophan synthase from2 vibrio cholerae o1 biovar el tor str. n16961
107d1rpxa_
not modelled 99.5 15 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:D-ribulose-5-phosphate 3-epimerase
108d1hg3a_
not modelled 99.5 15 Fold:TIM beta/alpha-barrel
Superfamily:Triosephosphate isomerase (TIM)
Family:Triosephosphate isomerase (TIM)
109d1h1ya_
not modelled 99.5 16 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:D-ribulose-5-phosphate 3-epimerase
110d1q6oa_
not modelled 99.5 10 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Decarboxylase
111d2flia1
not modelled 99.5 12 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:D-ribulose-5-phosphate 3-epimerase
112c2zbtB_
not modelled 99.5 27 PDB header:lyase
Chain: B: PDB Molecule:pyridoxal biosynthesis lyase pdxs;
PDBTitle: crystal structure of pyridoxine biosynthesis protein from thermus2 thermophilus hb8
113c2nv2U_
not modelled 99.5 28 PDB header:lyase/transferase
Chain: U: PDB Molecule:pyridoxal biosynthesis lyase pdxs;
PDBTitle: structure of the plp synthase complex pdx1/2 (yaad/e) from bacillus2 subtilis
114d1q45a_
not modelled 99.5 17 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
115d1tqxa_
not modelled 99.4 13 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:D-ribulose-5-phosphate 3-epimerase
116d1vzwa1
not modelled 99.4 18 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Histidine biosynthesis enzymes
117c3inpA_
not modelled 99.4 17 PDB header:isomerase
Chain: A: PDB Molecule:d-ribulose-phosphate 3-epimerase;
PDBTitle: 2.05 angstrom resolution crystal structure of d-ribulose-phosphate 3-2 epimerase from francisella tularensis.
118d1tqja_
not modelled 99.4 16 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:D-ribulose-5-phosphate 3-epimerase
119c3exsB_
not modelled 99.4 14 PDB header:lyase
Chain: B: PDB Molecule:rmpd (hexulose-6-phosphate synthase);
PDBTitle: crystal structure of kgpdc from streptococcus mutans in2 complex with d-r5p
120c3l5aA_
not modelled 99.4 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:nadh/flavin oxidoreductase/nadh oxidase;
PDBTitle: crystal structure of a probable nadh-dependent flavin oxidoreductase2 from staphylococcus aureus

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0