Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP46130
DateThu Jan 5 12:04:05 GMT 2012
Unique Job ID6be7df39e593cd44

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c3grhA_
Top template information
PDB header:hydrolase
Chain: A: PDB Molecule:acyl-coa thioester hydrolase ybgc;
PDBTitle: crystal structure of escherichia coli ybhc
Confidence and coverage
Confidence:100.0% Coverage: 92%
392 residues ( 92% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MNTFSVSRLALALAFGVTLTACSSTPPDQRPSDQTAPGTSSRPILSAKEAQNFDAQHYFA
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Disorder  ???????













?????????????????????


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   .........70.........80.........90.........100.........110.........120
Sequence  SLTPGAAAWNPSPITLPAQPDFVVGPAGTQGVTHTTIQAAVDAAIIKRTNKRQYIAVMPG
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   .........130.........140.........150.........160.........170.........180
Sequence  EYQGTVYVPAAPGGITLYGTGEKPIDVKIGLSLDGGMSPADWRHDVNPRGKYMPGKPAWY
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   .........190.........200.........210.........220.........230.........240
Sequence  MYDSCQSKRSDSIGVLCSAVFWSQNNGLQLQNLTIENTLGDSVDAGNHPAVALRTDGDQV
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??






























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   .........250.........260.........270.........280.........290.........300
Sequence  QINNVNILGRQNTFFVTNSGVQNRLETNRQPRTLVTNSYIEGDVDIVSGRGAVVFDNTEF
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   .........310.........320.........330.........340.........350.........360
Sequence  RVVNSRTQQEAYVFAPATLSNIYYGFLAVNSRFNAFGDGVAQLGRSLDVDANTNGQVVIR
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??
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   .........370.........380.........390.........400.........410.........420
Sequence  DSAINEGFNTAKPWADAVISNRPFAGNTGSVDDNDEIQRNLNDTNYNRMWEYNNRGVGSK
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???








?
??????
??

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??
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   .......
Sequence  VVAEAKK
Secondary structure 






SS confidence 






Disorder  ???????
Disorder confidence 






 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 3grh chain A

3D model

Region: 29 - 420
Aligned: 392
Modelled: 392
Confidence: 100.0%
Identity: 100%
PDB header:hydrolase
Chain: A: PDB Molecule:acyl-coa thioester hydrolase ybgc;
PDBTitle: crystal structure of escherichia coli ybhc

Phyre2

PDB 1gq8 chain A

3D model

Region: 75 - 426
Aligned: 271
Modelled: 272
Confidence: 100.0%
Identity: 30%
Fold: Single-stranded right-handed beta-helix
Superfamily: Pectin lyase-like
Family: Pectin methylesterase

Phyre2

PDB 1xg2 chain A

3D model

Region: 78 - 426
Aligned: 268
Modelled: 278
Confidence: 100.0%
Identity: 29%
PDB header:hydrolase/hydrolase inhibitor
Chain: A: PDB Molecule:pectinesterase 1;
PDBTitle: crystal structure of the complex between pectin2 methylesterase and its inhibitor protein

Phyre2

PDB 1qjv chain A

3D model

Region: 78 - 427
Aligned: 288
Modelled: 295
Confidence: 100.0%
Identity: 26%
Fold: Single-stranded right-handed beta-helix
Superfamily: Pectin lyase-like
Family: Pectin methylesterase

Phyre2

PDB 1ofl chain A

3D model

Region: 92 - 250
Aligned: 106
Modelled: 113
Confidence: 99.0%
Identity: 13%
Fold: Single-stranded right-handed beta-helix
Superfamily: Pectin lyase-like
Family: Chondroitinase B

Phyre2

PDB 1dbg chain A

3D model

Region: 83 - 284
Aligned: 141
Modelled: 156
Confidence: 98.9%
Identity: 13%
PDB header:lyase
Chain: A: PDB Molecule:chondroitinase b;
PDBTitle: crystal structure of chondroitinase b

Phyre2

PDB 1ru4 chain A

3D model

Region: 76 - 301
Aligned: 194
Modelled: 201
Confidence: 98.9%
Identity: 16%
Fold: Single-stranded right-handed beta-helix
Superfamily: Pectin lyase-like
Family: Pectate transeliminase

Phyre2

PDB 1bhe chain A

3D model

Region: 70 - 367
Aligned: 284
Modelled: 298
Confidence: 98.7%
Identity: 11%
Fold: Single-stranded right-handed beta-helix
Superfamily: Pectin lyase-like
Family: Galacturonase

Phyre2

PDB 3eqn chain B

3D model

Region: 18 - 367
Aligned: 302
Modelled: 321
Confidence: 98.7%
Identity: 15%
PDB header:hydrolase
Chain: B: PDB Molecule:glucan 1,3-beta-glucosidase;
PDBTitle: crystal structure of beta-1,3-glucanase from phanerochaete2 chrysosporium (lam55a)

Phyre2

PDB 1czf chain A

3D model

Region: 87 - 367
Aligned: 242
Modelled: 263
Confidence: 98.5%
Identity: 14%
Fold: Single-stranded right-handed beta-helix
Superfamily: Pectin lyase-like
Family: Galacturonase

Phyre2

PDB 1czf chain B

3D model

Region: 87 - 367
Aligned: 242
Modelled: 267
Confidence: 98.5%
Identity: 13%
PDB header:hydrolase
Chain: B: PDB Molecule:polygalacturonase ii;
PDBTitle: endo-polygalacturonase ii from aspergillus niger

Phyre2

PDB 2pyh chain B

3D model

Region: 86 - 343
Aligned: 233
Modelled: 258
Confidence: 98.4%
Identity: 13%
PDB header:isomerase
Chain: B: PDB Molecule:poly(beta-d-mannuronate) c5 epimerase 4;
PDBTitle: azotobacter vinelandii mannuronan c-5 epimerase alge4 a-module2 complexed with mannuronan trisaccharide

Phyre2

PDB 2iq7 chain D

3D model

Region: 97 - 367
Aligned: 234
Modelled: 254
Confidence: 98.2%
Identity: 15%
PDB header:hydrolase
Chain: D: PDB Molecule:endopolygalacturonase;
PDBTitle: crystal structure of the polygalacturonase from colletotrichum lupini2 and its implications for the interaction with polygalacturonase-3 inhibiting proteins

Phyre2

PDB 1nhc chain A

3D model

Region: 97 - 369
Aligned: 235
Modelled: 259
Confidence: 98.0%
Identity: 13%
Fold: Single-stranded right-handed beta-helix
Superfamily: Pectin lyase-like
Family: Galacturonase

Phyre2

PDB 2uve chain A

3D model

Region: 86 - 343
Aligned: 241
Modelled: 251
Confidence: 98.0%
Identity: 16%
PDB header:hydrolase
Chain: A: PDB Molecule:exopolygalacturonase;
PDBTitle: structure of yersinia enterocolitica family 282 exopolygalacturonase

Phyre2

PDB 2inu chain C

3D model

Region: 85 - 332
Aligned: 214
Modelled: 228
Confidence: 98.0%
Identity: 14%
PDB header:lyase
Chain: C: PDB Molecule:insulin fructotransferase;
PDBTitle: crystal structure of insulin fructotransferase in the absence of2 substrate

Phyre2

PDB 1hg8 chain A

3D model

Region: 93 - 367
Aligned: 250
Modelled: 261
Confidence: 98.0%
Identity: 15%
Fold: Single-stranded right-handed beta-helix
Superfamily: Pectin lyase-like
Family: Galacturonase

Phyre2

PDB 1ia5 chain A

3D model

Region: 83 - 370
Aligned: 249
Modelled: 268
Confidence: 97.9%
Identity: 12%
Fold: Single-stranded right-handed beta-helix
Superfamily: Pectin lyase-like
Family: Galacturonase

Phyre2

PDB 3jur chain A

3D model

Region: 97 - 366
Aligned: 256
Modelled: 266
Confidence: 97.7%
Identity: 14%
PDB header:hydrolase
Chain: A: PDB Molecule:exo-poly-alpha-d-galacturonosidase;
PDBTitle: the crystal structure of a hyperthermoactive exopolygalacturonase from2 thermotoga maritima

Phyre2

PDB 1rmg chain A

3D model

Region: 87 - 370
Aligned: 238
Modelled: 258
Confidence: 97.2%
Identity: 10%
Fold: Single-stranded right-handed beta-helix
Superfamily: Pectin lyase-like
Family: Galacturonase

Phyre2
1

c3grhA_
2

d1gq8a_
3

c1xg2A_
4

d1qjva_
5

d1ofla_
6

c1dbgA_
7

d1ru4a_
8

d1bhea_
9

c3eqnB_
10

d1czfa_
11

c1czfB_
12

c2pyhB_
13

c2iq7D_
14

d1nhca_
15

c2uveA_
16

c2inuC_
17

d1hg8a_
18

d1ia5a_
19

c3jurA_
20

d1rmga_
21



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49



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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c3grhA_



100.0 100 PDB header:hydrolase
Chain: A: PDB Molecule:acyl-coa thioester hydrolase ybgc;
PDBTitle: crystal structure of escherichia coli ybhc
2d1gq8a_



100.0 30 Fold:Single-stranded right-handed beta-helix
Superfamily:Pectin lyase-like
Family:Pectin methylesterase
3c1xg2A_



100.0 29 PDB header:hydrolase/hydrolase inhibitor
Chain: A: PDB Molecule:pectinesterase 1;
PDBTitle: crystal structure of the complex between pectin2 methylesterase and its inhibitor protein
4d1qjva_



100.0 26 Fold:Single-stranded right-handed beta-helix
Superfamily:Pectin lyase-like
Family:Pectin methylesterase
5d1ofla_



99.0 13 Fold:Single-stranded right-handed beta-helix
Superfamily:Pectin lyase-like
Family:Chondroitinase B
6c1dbgA_



98.9 13 PDB header:lyase
Chain: A: PDB Molecule:chondroitinase b;
PDBTitle: crystal structure of chondroitinase b
7d1ru4a_



98.9 16 Fold:Single-stranded right-handed beta-helix
Superfamily:Pectin lyase-like
Family:Pectate transeliminase
8d1bhea_



98.7 11 Fold:Single-stranded right-handed beta-helix
Superfamily:Pectin lyase-like
Family:Galacturonase
9c3eqnB_



98.7 15 PDB header:hydrolase
Chain: B: PDB Molecule:glucan 1,3-beta-glucosidase;
PDBTitle: crystal structure of beta-1,3-glucanase from phanerochaete2 chrysosporium (lam55a)
10d1czfa_



98.5 14 Fold:Single-stranded right-handed beta-helix
Superfamily:Pectin lyase-like
Family:Galacturonase
11c1czfB_



98.5 13 PDB header:hydrolase
Chain: B: PDB Molecule:polygalacturonase ii;
PDBTitle: endo-polygalacturonase ii from aspergillus niger
12c2pyhB_



98.4 13 PDB header:isomerase
Chain: B: PDB Molecule:poly(beta-d-mannuronate) c5 epimerase 4;
PDBTitle: azotobacter vinelandii mannuronan c-5 epimerase alge4 a-module2 complexed with mannuronan trisaccharide
13c2iq7D_



98.2 15 PDB header:hydrolase
Chain: D: PDB Molecule:endopolygalacturonase;
PDBTitle: crystal structure of the polygalacturonase from colletotrichum lupini2 and its implications for the interaction with polygalacturonase-3 inhibiting proteins
14d1nhca_



98.0 13 Fold:Single-stranded right-handed beta-helix
Superfamily:Pectin lyase-like
Family:Galacturonase
15c2uveA_



98.0 16 PDB header:hydrolase
Chain: A: PDB Molecule:exopolygalacturonase;
PDBTitle: structure of yersinia enterocolitica family 282 exopolygalacturonase
16c2inuC_



98.0 14 PDB header:lyase
Chain: C: PDB Molecule:insulin fructotransferase;
PDBTitle: crystal structure of insulin fructotransferase in the absence of2 substrate
17d1hg8a_



98.0 15 Fold:Single-stranded right-handed beta-helix
Superfamily:Pectin lyase-like
Family:Galacturonase
18d1ia5a_



97.9 12 Fold:Single-stranded right-handed beta-helix
Superfamily:Pectin lyase-like
Family:Galacturonase
19c3jurA_



97.7 14 PDB header:hydrolase
Chain: A: PDB Molecule:exo-poly-alpha-d-galacturonosidase;
PDBTitle: the crystal structure of a hyperthermoactive exopolygalacturonase from2 thermotoga maritima
20d1rmga_



97.2 10 Fold:Single-stranded right-handed beta-helix
Superfamily:Pectin lyase-like
Family:Galacturonase
21c3gqnA_



not modelled 96.9 15 PDB header:viral protein
Chain: A: PDB Molecule:preneck appendage protein;
PDBTitle: crystal structure of the pre-mature bacteriophage phi29 gene product2 12
22c3gq8A_



not modelled 96.5 12 PDB header:viral protein
Chain: A: PDB Molecule:preneck appendage protein;
PDBTitle: crystal structure of the bacteriophage phi29 gene product2 12 n-terminal fragment in complex with 2-(n-3 cyclohexylamino)ethane sulfonic acid (ches)
23c2qy1B_



not modelled 96.4 21 PDB header:lyase
Chain: B: PDB Molecule:pectate lyase ii;
PDBTitle: pectate lyase a31g/r236f from xanthomonas campestris
24d1idka_



not modelled 96.0 28 Fold:Single-stranded right-handed beta-helix
Superfamily:Pectin lyase-like
Family:Pectin lyase
25d1pcla_



not modelled 95.6 21 Fold:Single-stranded right-handed beta-helix
Superfamily:Pectin lyase-like
Family:Pectate lyase-like
26d1qcxa_



not modelled 95.2 25 Fold:Single-stranded right-handed beta-helix
Superfamily:Pectin lyase-like
Family:Pectin lyase
27d1bn8a_



not modelled 95.0 18 Fold:Single-stranded right-handed beta-helix
Superfamily:Pectin lyase-like
Family:Pectate lyase-like
28d1k5ca_



not modelled 94.9 12 Fold:Single-stranded right-handed beta-helix
Superfamily:Pectin lyase-like
Family:Galacturonase
29d1pe9a_



not modelled 93.9 27 Fold:Single-stranded right-handed beta-helix
Superfamily:Pectin lyase-like
Family:Pectate lyase-like
30d1ogmx2



not modelled 93.4 11 Fold:Single-stranded right-handed beta-helix
Superfamily:Pectin lyase-like
Family:Dextranase, catalytic domain
31d1o88a_



not modelled 93.4 21 Fold:Single-stranded right-handed beta-helix
Superfamily:Pectin lyase-like
Family:Pectate lyase-like
32c2vjjA_



not modelled 92.8 19 PDB header:viral protein
Chain: A: PDB Molecule:tailspike protein;
PDBTitle: tailspike protein of e.coli bacteriophage hk620 in complex2 with hexasaccharide
33c1vblA_



not modelled 92.4 23 PDB header:lyase
Chain: A: PDB Molecule:pectate lyase 47;
PDBTitle: structure of the thermostable pectate lyase pl 47
34c2z8gB_



not modelled 85.1 15 PDB header:hydrolase
Chain: B: PDB Molecule:isopullulanase;
PDBTitle: aspergillus niger atcc9642 isopullulanase complexed with isopanose
35d1pxza_



not modelled 85.0 19 Fold:Single-stranded right-handed beta-helix
Superfamily:Pectin lyase-like
Family:Pectate lyase-like
36c1ogoX_



not modelled 41.2 13 PDB header:hydrolase
Chain: X: PDB Molecule:dextranase;
PDBTitle: dex49a from penicillium minioluteum complex with isomaltose
37d1j83a_



not modelled 18.8 23 Fold:Galactose-binding domain-like
Superfamily:Galactose-binding domain-like
Family:Family 17 carbohydrate binding module, CBM17
38c3cegA_



not modelled 18.1 26 PDB header:ligase
Chain: A: PDB Molecule:baculoviral iap repeat-containing protein 6;
PDBTitle: crystal structure of the ubc domain of baculoviral iap2 repeat-containing protein 6
39d1acoa1



not modelled 16.2 20 Fold:The "swivelling" beta/beta/alpha domain
Superfamily:LeuD/IlvD-like
Family:LeuD-like
40c2l02B_



not modelled 12.3 45 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:uncharacterized protein;
PDBTitle: solution nmr structure of protein bt2368 from bacteroides2 thetaiotaomicron, northeast structural genomics consortium target3 btr375
41c2p4gA_



not modelled 10.9 7 PDB header:oxidoreductase
Chain: A: PDB Molecule:hypothetical protein;
PDBTitle: crystal structure of a pyrimidine reductase-like protein (dip1392)2 from corynebacterium diphtheriae nctc at 2.30 a resolution
42c3owvA_



not modelled 10.0 7 PDB header:hydrolase
Chain: A: PDB Molecule:dna-entry nuclease;
PDBTitle: structural insights into catalytic and substrate binding mechanisms of2 the strategic enda nuclease from streptococcus pneumoniae
43c2vbeA_



not modelled 9.9 29 PDB header:viral protein
Chain: A: PDB Molecule:tailspike-protein;
PDBTitle: tailspike protein of bacteriophage sf6
44d1dmla1



not modelled 9.8 20 Fold:DNA clamp
Superfamily:DNA clamp
Family:DNA polymerase processivity factor
45c2xz8A_



not modelled 9.1 33 PDB header:immune system
Chain: A: PDB Molecule:peptidoglycan-recognition protein lf;
PDBTitle: crystal structure of the lfw ectodomain of the2 peptidoglycan recognition protein lf
46c1dmlG_



not modelled 8.9 20 PDB header:dna binding protein/transferase
Chain: G: PDB Molecule:dna polymerase processivity factor;
PDBTitle: crystal structure of herpes simplex ul42 bound to the c-2 terminus of hsv pol
47c2rfyB_



not modelled 8.9 36 PDB header:hydrolase
Chain: B: PDB Molecule:cellulose 1,4-beta-cellobiosidase;
PDBTitle: crystal structure of cellobiohydrolase from melanocarpus2 albomyces complexed with cellobiose
48d2nn6h3



not modelled 8.4 17 Fold:Eukaryotic type KH-domain (KH-domain type I)
Superfamily:Eukaryotic type KH-domain (KH-domain type I)
Family:Eukaryotic type KH-domain (KH-domain type I)
49c2qyvB_



not modelled 7.8 19 PDB header:hydrolase
Chain: B: PDB Molecule:xaa-his dipeptidase;
PDBTitle: crystal structure of putative xaa-his dipeptidase (yp_718209.1) from2 haemophilus somnus 129pt at 2.11 a resolution
50d1autl2



not modelled 7.7 40 Fold:Knottins (small inhibitors, toxins, lectins)
Superfamily:EGF/Laminin
Family:EGF-type module
51d1ckva_



not modelled 7.6 50 Fold:Monooxygenase (hydroxylase) regulatory protein
Superfamily:Monooxygenase (hydroxylase) regulatory protein
Family:Monooxygenase (hydroxylase) regulatory protein
52c3b4qA_



not modelled 7.5 29 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of a conserved protein domain (unknown2 function) from corynebacterium diphtheriae
53c3ep1B_



not modelled 7.1 38 PDB header:immune system
Chain: B: PDB Molecule:pgrp-hd - peptidoglycan recognition protein
PDBTitle: structure of the pgrp-hd from alvinella pompejana
54d2cu8a1



not modelled 7.0 21 Fold:Glucocorticoid receptor-like (DNA-binding domain)
Superfamily:Glucocorticoid receptor-like (DNA-binding domain)
Family:LIM domain
55c3gw6F_



not modelled 6.6 21 PDB header:chaperone
Chain: F: PDB Molecule:endo-n-acetylneuraminidase;
PDBTitle: intramolecular chaperone
56d1hqia_



not modelled 6.0 67 Fold:Monooxygenase (hydroxylase) regulatory protein
Superfamily:Monooxygenase (hydroxylase) regulatory protein
Family:Monooxygenase (hydroxylase) regulatory protein
57d1ex4a1



not modelled 5.8 37 Fold:SH3-like barrel
Superfamily:DNA-binding domain of retroviral integrase
Family:DNA-binding domain of retroviral integrase
58d1el6a_



not modelled 5.8 25 Fold:Baseplate structural protein gp11
Superfamily:Baseplate structural protein gp11
Family:Baseplate structural protein gp11
59d2moba_



not modelled 5.6 40 Fold:Monooxygenase (hydroxylase) regulatory protein
Superfamily:Monooxygenase (hydroxylase) regulatory protein
Family:Monooxygenase (hydroxylase) regulatory protein
60c2mobA_



not modelled 5.6 40 PDB header:oxidoreductase
Chain: A: PDB Molecule:protein (methane monooxygenase regulatory
PDBTitle: methane monooxygenase component b
61c3rlcA_



not modelled 5.2 21 PDB header:structural protein
Chain: A: PDB Molecule:a1 protein;
PDBTitle: crystal structure of the read-through domain from bacteriophage qbeta2 a1 protein, hexagonal crystal form
62d1k4ia_



not modelled 5.1 10 Fold:YrdC/RibB
Superfamily:YrdC/RibB
Family:3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase, RibB
63d1xpaa2



not modelled 5.1 27 Fold:Glucocorticoid receptor-like (DNA-binding domain)
Superfamily:Glucocorticoid receptor-like (DNA-binding domain)
Family:DNA repair factor XPA DNA- and RPA-binding domain, N-terminal subdomain
64c1s2jA_



not modelled 5.0 25 PDB header:hydrolase
Chain: A: PDB Molecule:peptidoglycan recognition protein sa cg11709-pa;
PDBTitle: crystal structure of the drosophila pattern-recognition2 receptor pgrp-sa
65d1jb0d_



not modelled 5.0 14 Fold:Photosystem I subunit PsaD
Superfamily:Photosystem I subunit PsaD
Family:Photosystem I subunit PsaD

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0