Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	Q	I	L	L	A	N	P	R	G	F	C	A	G	V	D	R	A	I	S	I	V	E	N	A	L	A	I	Y	G	A	P	I	Y	V	R	H	E	V	V	H	N	R	Y	V	V	D	S	L	R	E	R	G	A	I	F	I	E	Q	I
Secondary structure
SS confidence
Disorder		?					?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		S	E	V	P	D	G	A	I	L	I	F	S	A	H	G	V	S	Q	A	V	R	N	E	A	K	S	R	D	L	T	V	F	D	A	T	C	P	L	V	T	K	V	H	M	E	V	A	R	A	S	R	R	G	E	E	S	I	L	I	G
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		H	A	G	H	P	E	V	E	G	T	M	G	Q	Y	S	N	P	E	G	G	M	Y	L	V	E	S	P	D	D	V	W	K	L	T	V	K	N	E	E	K	L	S	F	M	T	Q	T	T	L	S	V	D	D	T	S	D	V	I	D	A
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		L	R	K	R	F	P	K	I	V	G	P	R	K	D	D	I	C	Y	A	T	T	N	R	Q	E	A	V	R	A	L	A	E	Q	A	E	V	V	L	V	V	G	S	K	N	S	S	N	S	N	R	L	A	E	L	A	Q	R	M	G	K
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		R	A	F	L	I	D	D	A	K	D	I	Q	E	E	W	V	K	E	V	K	C	V	G	V	T	A	G	A	S	A	P	D	I	L	V	Q	N	V	V	A	R	L	Q	Q	L	G	G	G	E	A	I	P	L	E	G	R	E	E	N	I
Secondary structure
SS confidence
Disorder																																																?	?	?	?						?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.
Sequence		V	F	E	V	P	K	E	L	R	V	D	I	R	E	V	D
Secondary structure
SS confidence
Disorder											?		?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3ke8 chain A Region: 1 - 309 Aligned: 309 Modelled: 309 Confidence: 100.0% Identity: 100% PDB header:oxidoreductase Chain: A: PDB Molecule:4-hydroxy-3-methylbut-2-enyl diphosphate PDBTitle: crystal structure of isph:hmbpp-complex Phyre2 PDB 3dnf chain B Region: 1 - 285 Aligned: 280 Modelled: 280 Confidence: 100.0% Identity: 33% PDB header:oxidoreductase Chain: B: PDB Molecule:4-hydroxy-3-methylbut-2-enyl diphosphate reductase; PDBTitle: structure of (e)-4-hydroxy-3-methyl-but-2-enyl diphosphate reductase,2 the terminal enzyme of the non-mevalonate pathway Phyre2 PDB 3j09 chain A Region: 37 - 271 Aligned: 189 Modelled: 200 Confidence: 86.1% Identity: 13% PDB header:hydrolase, metal transport Chain: A: PDB Molecule:copper-exporting p-type atpase a; PDBTitle: high resolution helical reconstruction of the bacterial p-type atpase2 copper transporter copa Phyre2 PDB 1ma3 chain A Region: 201 - 288 Aligned: 81 Modelled: 88 Confidence: 84.9% Identity: 15% Fold: DHS-like NAD/FAD-binding domain Superfamily: DHS-like NAD/FAD-binding domain Family: Sir2 family of transcriptional regulators Phyre2 PDB 1m2k chain A Region: 201 - 285 Aligned: 78 Modelled: 85 Confidence: 84.7% Identity: 15% Fold: DHS-like NAD/FAD-binding domain Superfamily: DHS-like NAD/FAD-binding domain Family: Sir2 family of transcriptional regulators Phyre2 PDB 3ff4 chain A Region: 43 - 100 Aligned: 45 Modelled: 57 Confidence: 84.5% Identity: 13% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of uncharacterized protein chu_1412 Phyre2 PDB 3pki chain F Region: 205 - 246 Aligned: 42 Modelled: 42 Confidence: 79.1% Identity: 17% PDB header:hydrolase Chain: F: PDB Molecule:nad-dependent deacetylase sirtuin-6; PDBTitle: human sirt6 crystal structure in complex with adp ribose Phyre2 PDB 1s5p chain A Region: 204 - 246 Aligned: 43 Modelled: 43 Confidence: 76.5% Identity: 9% Fold: DHS-like NAD/FAD-binding domain Superfamily: DHS-like NAD/FAD-binding domain Family: Sir2 family of transcriptional regulators Phyre2 PDB 3h5l chain B Region: 187 - 243 Aligned: 57 Modelled: 57 Confidence: 76.3% Identity: 16% PDB header:transport protein Chain: B: PDB Molecule:putative branched-chain amino acid abc PDBTitle: crystal structure of a putative branched-chain amino acid2 abc transporter from silicibacter pomeroyi Phyre2 PDB 1kbl chain A Region: 11 - 57 Aligned: 47 Modelled: 47 Confidence: 75.7% Identity: 13% PDB header:transferase Chain: A: PDB Molecule:pyruvate phosphate dikinase; PDBTitle: pyruvate phosphate dikinase Phyre2 PDB 3j08 chain A Region: 37 - 270 Aligned: 188 Modelled: 199 Confidence: 75.1% Identity: 12% PDB header:hydrolase, metal transport Chain: A: PDB Molecule:copper-exporting p-type atpase a; PDBTitle: high resolution helical reconstruction of the bacterial p-type atpase2 copper transporter copa Phyre2 PDB 1yc5 chain A domain 1 Region: 205 - 246 Aligned: 42 Modelled: 42 Confidence: 74.8% Identity: 19% Fold: DHS-like NAD/FAD-binding domain Superfamily: DHS-like NAD/FAD-binding domain Family: Sir2 family of transcriptional regulators Phyre2 PDB 1j6u chain A domain 1 Region: 24 - 93 Aligned: 68 Modelled: 70 Confidence: 74.5% Identity: 12% Fold: MurCD N-terminal domain Superfamily: MurCD N-terminal domain Family: MurCD N-terminal domain Phyre2 PDB 2bg5 chain C Region: 10 - 57 Aligned: 48 Modelled: 48 Confidence: 72.6% Identity: 17% PDB header:transferase Chain: C: PDB Molecule:phosphoenolpyruvate-protein kinase; PDBTitle: crystal structure of the phosphoenolpyruvate-binding enzyme2 i-domain from the thermoanaerobacter tengcongensis pep:3 sugar phosphotransferase system (pts) Phyre2 PDB 3afo chain B Region: 156 - 222 Aligned: 67 Modelled: 67 Confidence: 72.3% Identity: 10% PDB header:transferase Chain: B: PDB Molecule:nadh kinase pos5; PDBTitle: crystal structure of yeast nadh kinase complexed with nadh Phyre2 PDB 2ols chain A Region: 14 - 57 Aligned: 44 Modelled: 44 Confidence: 71.4% Identity: 11% PDB header:transferase Chain: A: PDB Molecule:phosphoenolpyruvate synthase; PDBTitle: the crystal structure of the phosphoenolpyruvate synthase from2 neisseria meningitidis Phyre2 PDB 3l4e chain A Region: 151 - 268 Aligned: 104 Modelled: 118 Confidence: 69.8% Identity: 20% PDB header:hydrolase Chain: A: PDB Molecule:uncharacterized peptidase lmo0363; PDBTitle: 1.5a crystal structure of a putative peptidase e protein from listeria2 monocytogenes egd-e Phyre2 PDB 3d22 chain A Region: 170 - 289 Aligned: 108 Modelled: 120 Confidence: 69.8% Identity: 11% PDB header:oxidoreductase Chain: A: PDB Molecule:thioredoxin h-type; PDBTitle: crystal structure of a poplar thioredoxin h mutant,2 pttrxh4c61s Phyre2 PDB 1xmt chain A Region: 78 - 103 Aligned: 25 Modelled: 26 Confidence: 69.7% Identity: 20% Fold: Acyl-CoA N-acyltransferases (Nat) Superfamily: Acyl-CoA N-acyltransferases (Nat) Family: N-acetyl transferase, NAT Phyre2 PDB 1s1p chain A Region: 176 - 309 Aligned: 127 Modelled: 134 Confidence: 69.0% Identity: 16% Fold: TIM beta/alpha-barrel Superfamily: NAD(P)-linked oxidoreductase Family: Aldo-keto reductases (NADP) Phyre2 1 c3ke8A_ 2 c3dnfB_ 3 c3j09A_ 4 d1ma3a_ 5 d1m2ka_ 6 c3ff4A_ 7 c3pkiF_ 8 d1s5pa_ 9 c3h5lB_ 10 c1kblA_ 11 c3j08A_ 12 d1yc5a1 13 d1j6ua1 14 c2bg5C_ 15 c3afoB_ 16 c2olsA_ 17 c3l4eA_ 18 c3d22A_ 19 d1xmta_ 20 d1s1pa_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3ke8A_ 100.0 100 PDB header:oxidoreductase Chain: A: PDB Molecule:4-hydroxy-3-methylbut-2-enyl diphosphate PDBTitle: crystal structure of isph:hmbpp-complex 2 c3dnfB_ 100.0 33 PDB header:oxidoreductase Chain: B: PDB Molecule:4-hydroxy-3-methylbut-2-enyl diphosphate reductase; PDBTitle: structure of (e)-4-hydroxy-3-methyl-but-2-enyl diphosphate reductase,2 the terminal enzyme of the non-mevalonate pathway 3 c3j09A_ 86.1 13 PDB header:hydrolase, metal transport Chain: A: PDB Molecule:copper-exporting p-type atpase a; PDBTitle: high resolution helical reconstruction of the bacterial p-type atpase2 copper transporter copa 4 d1ma3a_ 84.9 15 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Sir2 family of transcriptional regulators 5 d1m2ka_ 84.7 15 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Sir2 family of transcriptional regulators 6 c3ff4A_ 84.5 13 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of uncharacterized protein chu_1412 7 c3pkiF_ 79.1 17 PDB header:hydrolase Chain: F: PDB Molecule:nad-dependent deacetylase sirtuin-6; PDBTitle: human sirt6 crystal structure in complex with adp ribose 8 d1s5pa_ 76.5 9 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Sir2 family of transcriptional regulators 9 c3h5lB_ 76.3 16 PDB header:transport protein Chain: B: PDB Molecule:putative branched-chain amino acid abc PDBTitle: crystal structure of a putative branched-chain amino acid2 abc transporter from silicibacter pomeroyi 10 c1kblA_ 75.7 13 PDB header:transferase Chain: A: PDB Molecule:pyruvate phosphate dikinase; PDBTitle: pyruvate phosphate dikinase 11 c3j08A_ 75.1 12 PDB header:hydrolase, metal transport Chain: A: PDB Molecule:copper-exporting p-type atpase a; PDBTitle: high resolution helical reconstruction of the bacterial p-type atpase2 copper transporter copa 12 d1yc5a1 74.8 19 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Sir2 family of transcriptional regulators 13 d1j6ua1 74.5 12 Fold:MurCD N-terminal domain Superfamily:MurCD N-terminal domain Family:MurCD N-terminal domain 14 c2bg5C_ 72.6 17 PDB header:transferase Chain: C: PDB Molecule:phosphoenolpyruvate-protein kinase; PDBTitle: crystal structure of the phosphoenolpyruvate-binding enzyme2 i-domain from the thermoanaerobacter tengcongensis pep:3 sugar phosphotransferase system (pts) 15 c3afoB_ 72.3 10 PDB header:transferase Chain: B: PDB Molecule:nadh kinase pos5; PDBTitle: crystal structure of yeast nadh kinase complexed with nadh 16 c2olsA_ 71.4 11 PDB header:transferase Chain: A: PDB Molecule:phosphoenolpyruvate synthase; PDBTitle: the crystal structure of the phosphoenolpyruvate synthase from2 neisseria meningitidis 17 c3l4eA_ 69.8 20 PDB header:hydrolase Chain: A: PDB Molecule:uncharacterized peptidase lmo0363; PDBTitle: 1.5a crystal structure of a putative peptidase e protein from listeria2 monocytogenes egd-e 18 c3d22A_ 69.8 11 PDB header:oxidoreductase Chain: A: PDB Molecule:thioredoxin h-type; PDBTitle: crystal structure of a poplar thioredoxin h mutant,2 pttrxh4c61s 19 d1xmta_ 69.7 20 Fold:Acyl-CoA N-acyltransferases (Nat) Superfamily:Acyl-CoA N-acyltransferases (Nat) Family:N-acetyl transferase, NAT 20 d1s1pa_ 69.0 16 Fold:TIM beta/alpha-barrel Superfamily:NAD(P)-linked oxidoreductase Family:Aldo-keto reductases (NADP) 21 d1fyea_ not modelled 68.2 17 Fold:Flavodoxin-like Superfamily:Class I glutamine amidotransferase-like Family:Aspartyl dipeptidase PepE 22 c3rfuC_ not modelled 67.1 15 PDB header:hydrolase, membrane protein Chain: C: PDB Molecule:copper efflux atpase; PDBTitle: crystal structure of a copper-transporting pib-type atpase 23 d1qo0a_ not modelled 65.5 16 Fold:Periplasmic binding protein-like I Superfamily:Periplasmic binding protein-like I Family:L-arabinose binding protein-like 24 c3cumA_ not modelled 65.4 24 PDB header:oxidoreductase Chain: A: PDB Molecule:probable 3-hydroxyisobutyrate dehydrogenase; PDBTitle: crystal structure of a possible 3-hydroxyisobutyrate dehydrogenase2 from pseudomonas aeruginosa pao1 25 c3h75A_ not modelled 65.1 10 PDB header:sugar binding protein Chain: A: PDB Molecule:periplasmic sugar-binding domain protein; PDBTitle: crystal structure of a periplasmic sugar-binding protein from the2 pseudomonas fluorescens 26 d1kbla1 not modelled 64.2 13 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Pyruvate phosphate dikinase, C-terminal domain 27 d1oj7a_ not modelled 63.7 10 Fold:Dehydroquinate synthase-like Superfamily:Dehydroquinate synthase-like Family:Iron-containing alcohol dehydrogenase 28 d2dlxa1 not modelled 62.8 11 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:UAS domain 29 d1oboa_ not modelled 62.2 7 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:Flavodoxin-related 30 d2j13a1 not modelled 61.8 12 Fold:7-stranded beta/alpha barrel Superfamily:Glycoside hydrolase/deacetylase Family:NodB-like polysaccharide deacetylase 31 c3k35D_ not modelled 60.0 15 PDB header:hydrolase Chain: D: PDB Molecule:nad-dependent deacetylase sirtuin-6; PDBTitle: crystal structure of human sirt6 32 c2iz6A_ not modelled 59.3 17 PDB header:metal transport Chain: A: PDB Molecule:molybdenum cofactor carrier protein; PDBTitle: structure of the chlamydomonas rheinhardtii moco carrier2 protein 33 c1j6uA_ not modelled 59.0 15 PDB header:ligase Chain: A: PDB Molecule:udp-n-acetylmuramate-alanine ligase murc; PDBTitle: crystal structure of udp-n-acetylmuramate-alanine ligase2 murc (tm0231) from thermotoga maritima at 2.3 a resolution 34 d1e0ta2 not modelled 57.9 12 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Pyruvate kinase 35 d1pkla2 not modelled 57.4 17 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Pyruvate kinase 36 c3ej6D_ not modelled 57.3 20 PDB header:oxidoreductase Chain: D: PDB Molecule:catalase-3; PDBTitle: neurospora crassa catalase-3 crystal structure 37 c2vlvA_ not modelled 56.8 16 PDB header:oxidoreductase Chain: A: PDB Molecule:thioredoxin h isoform 2.; PDBTitle: crystal structure of barley thioredoxin h isoform 2 in2 partially radiation-reduced state 38 d1w5fa1 not modelled 56.3 23 Fold:Tubulin nucleotide-binding domain-like Superfamily:Tubulin nucleotide-binding domain-like Family:Tubulin, GTPase domain 39 c1jzdA_ not modelled 55.9 19 PDB header:oxidoreductase Chain: A: PDB Molecule:thiol:disulfide interchange protein dsbc; PDBTitle: dsbc-dsbdalpha complex 40 c3mw8A_ not modelled 54.8 20 PDB header:lyase Chain: A: PDB Molecule:uroporphyrinogen-iii synthase; PDBTitle: crystal structure of an uroporphyrinogen-iii synthase (sama_3255) from2 shewanella amazonensis sb2b at 1.65 a resolution 41 c2hroA_ not modelled 54.4 15 PDB header:transferase Chain: A: PDB Molecule:phosphoenolpyruvate-protein phosphotransferase; PDBTitle: structure of the full-lenght enzyme i of the pts system from2 staphylococcus carnosus 42 d1ep7a_ not modelled 54.3 15 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase 43 d1ag9a_ not modelled 54.0 10 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:Flavodoxin-related 44 c3snrA_ not modelled 53.7 16 PDB header:transport protein Chain: A: PDB Molecule:extracellular ligand-binding receptor; PDBTitle: rpd_1889 protein, an extracellular ligand-binding receptor from2 rhodopseudomonas palustris. 45 c3oa3A_ not modelled 53.1 16 PDB header:lyase Chain: A: PDB Molecule:aldolase; PDBTitle: crystal structure of a putative deoxyribose-phosphate aldolase from2 coccidioides immitis 46 c3s40C_ not modelled 52.9 15 PDB header:transferase Chain: C: PDB Molecule:diacylglycerol kinase; PDBTitle: the crystal structure of a diacylglycerol kinases from bacillus2 anthracis str. sterne 47 d1ofua1 not modelled 52.8 23 Fold:Tubulin nucleotide-binding domain-like Superfamily:Tubulin nucleotide-binding domain-like Family:Tubulin, GTPase domain 48 c1t00A_ not modelled 52.5 10 PDB header:electron transport Chain: A: PDB Molecule:thioredoxin; PDBTitle: the structure of thioredoxin from s. coelicolor 49 d1h6za1 not modelled 52.3 9 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Pyruvate phosphate dikinase, C-terminal domain 50 d1r57a_ not modelled 52.2 22 Fold:Acyl-CoA N-acyltransferases (Nat) Superfamily:Acyl-CoA N-acyltransferases (Nat) Family:N-acetyl transferase, NAT 51 d2d59a1 not modelled 51.6 16 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:CoA-binding domain 52 d2hk6a1 not modelled 51.6 17 Fold:Chelatase-like Superfamily:Chelatase Family:Ferrochelatase 53 d1vbga1 not modelled 51.6 11 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Pyruvate phosphate dikinase, C-terminal domain 54 c1vbhA_ not modelled 51.3 13 PDB header:transferase Chain: A: PDB Molecule:pyruvate,orthophosphate dikinase; PDBTitle: pyruvate phosphate dikinase with bound mg-pep from maize 55 c3h6hB_ not modelled 50.5 13 PDB header:membrane protein Chain: B: PDB Molecule:glutamate receptor, ionotropic kainate 2; PDBTitle: crystal structure of the glur6 amino terminal domain dimer assembly2 mpd form 56 c3i09A_ not modelled 50.4 20 PDB header:transport protein Chain: A: PDB Molecule:periplasmic branched-chain amino acid-binding protein; PDBTitle: crystal structure of a periplasmic binding protein (bma2936) from2 burkholderia mallei at 1.80 a resolution 57 d1yq2a5 not modelled 49.7 21 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:beta-glycanases 58 c2h9aA_ not modelled 49.2 16 PDB header:oxidoreductase Chain: A: PDB Molecule:carbon monoxide dehydrogenase corrinoid/iron- PDBTitle: corrinoid iron-sulfur protein 59 c1zxxA_ not modelled 49.2 12 PDB header:transferase Chain: A: PDB Molecule:6-phosphofructokinase; PDBTitle: the crystal structure of phosphofructokinase from lactobacillus2 delbrueckii 60 c2hwgA_ not modelled 49.0 17 PDB header:transferase Chain: A: PDB Molecule:phosphoenolpyruvate-protein phosphotransferase; PDBTitle: structure of phosphorylated enzyme i of the2 phosphoenolpyruvate:sugar phosphotransferase system 61 d2g17a1 not modelled 48.9 21 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 62 c2vpiA_ not modelled 48.8 2 PDB header:ligase Chain: A: PDB Molecule:gmp synthase; PDBTitle: human gmp synthetase - glutaminase domain 63 c1w89E_ not modelled 48.6 16 PDB header:electron transport Chain: E: PDB Molecule:thioredoxin; PDBTitle: structure of the reduced form of human thioredoxin 2 64 d1j6ua2 not modelled 48.5 14 Fold:MurD-like peptide ligases, peptide-binding domain Superfamily:MurD-like peptide ligases, peptide-binding domain Family:MurCDEF C-terminal domain 65 c1t3bA_ not modelled 48.4 17 PDB header:isomerase Chain: A: PDB Molecule:thiol:disulfide interchange protein dsbc; PDBTitle: x-ray structure of dsbc from haemophilus influenzae 66 d2b4ya1 not modelled 48.0 19 Fold:DHS-like NAD/FAD-binding domain Superfamily:DHS-like NAD/FAD-binding domain Family:Sir2 family of transcriptional regulators 67 c3pfnB_ not modelled 46.1 12 PDB header:transferase Chain: B: PDB Molecule:nad kinase; PDBTitle: crystal structure of human nad kinase 68 c3tcoA_ not modelled 45.9 20 PDB header:oxidoreductase Chain: A: PDB Molecule:thioredoxin (trxa-1); PDBTitle: crystallographic and spectroscopic characterization of sulfolobus2 solfataricus trxa1 provide insights into the determinants of3 thioredoxin fold stability 69 c3hutA_ not modelled 45.1 15 PDB header:transport protein Chain: A: PDB Molecule:putative branched-chain amino acid abc PDBTitle: crystal structure of a putative branched-chain amino acid2 abc transporter from rhodospirillum rubrum 70 d2jfga1 not modelled 44.8 17 Fold:MurCD N-terminal domain Superfamily:MurCD N-terminal domain Family:MurCD N-terminal domain 71 d2je8a5 not modelled 44.7 16 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:beta-glycanases 72 d1qwka_ not modelled 44.2 12 Fold:TIM beta/alpha-barrel Superfamily:NAD(P)-linked oxidoreductase Family:Aldo-keto reductases (NADP) 73 d1a3xa2 not modelled 43.8 16 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Pyruvate kinase 74 d1t3ba1 not modelled 41.7 16 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:DsbC/DsbG C-terminal domain-like 75 c3k2qA_ not modelled 41.0 15 PDB header:transferase Chain: A: PDB Molecule:pyrophosphate-dependent phosphofructokinase; PDBTitle: crystal structure of pyrophosphate-dependent2 phosphofructokinase from marinobacter aquaeolei, northeast3 structural genomics consortium target mqr88 76 c3gnjD_ not modelled 40.4 13 PDB header:structural genomics, unknown function Chain: D: PDB Molecule:thioredoxin domain protein; PDBTitle: the crystal structure of a thioredoxin-related protein from2 desulfitobacterium hafniense dcb 77 c3la6P_ not modelled 40.0 10 PDB header:transferase Chain: P: PDB Molecule:tyrosine-protein kinase wzc; PDBTitle: octameric kinase domain of the e. coli tyrosine kinase wzc with bound2 adp 78 d1j96a_ not modelled 39.9 19 Fold:TIM beta/alpha-barrel Superfamily:NAD(P)-linked oxidoreductase Family:Aldo-keto reductases (NADP) 79 c3p9zA_ not modelled 39.9 13 PDB header:ligase Chain: A: PDB Molecule:uroporphyrinogen iii cosynthase (hemd); PDBTitle: crystal structure of uroporphyrinogen-iii synthetase from helicobacter2 pylori 26695 80 d1jhfa1 not modelled 39.8 15 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:LexA repressor, N-terminal DNA-binding domain 81 d1p3da1 not modelled 39.8 19 Fold:MurCD N-terminal domain Superfamily:MurCD N-terminal domain Family:MurCD N-terminal domain 82 c2qsiB_ not modelled 39.5 13 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative hydrogenase expression/formation protein hupg; PDBTitle: crystal structure of putative hydrogenase expression/formation protein2 hupg from rhodopseudomonas palustris cga009 83 c3n0xA_ not modelled 39.1 18 PDB header:transport protein Chain: A: PDB Molecule:possible substrate binding protein of abc transporter PDBTitle: crystal structure of an abc-type branched-chain amino acid transporter2 (rpa4397) from rhodopseudomonas palustris cga009 at 1.50 a resolution 84 d1jvna2 not modelled 38.9 16 Fold:Flavodoxin-like Superfamily:Class I glutamine amidotransferase-like Family:Class I glutamine amidotransferases (GAT) 85 d1vqof1 not modelled 38.7 21 Fold:Bacillus chorismate mutase-like Superfamily:L30e-like Family:L30e/L7ae ribosomal proteins 86 c3canA_ not modelled 38.7 12 PDB header:lyase activator Chain: A: PDB Molecule:pyruvate-formate lyase-activating enzyme; PDBTitle: crystal structure of a domain of pyruvate-formate lyase-activating2 enzyme from bacteroides vulgatus atcc 8482 87 d1hw6a_ not modelled 38.6 16 Fold:TIM beta/alpha-barrel Superfamily:NAD(P)-linked oxidoreductase Family:Aldo-keto reductases (NADP) 88 c1v57A_ not modelled 38.6 13 PDB header:isomerase Chain: A: PDB Molecule:thiol:disulfide interchange protein dsbg; PDBTitle: crystal structure of the disulfide bond isomerase dsbg 89 d1rlga_ not modelled 38.5 11 Fold:Bacillus chorismate mutase-like Superfamily:L30e-like Family:L30e/L7ae ribosomal proteins 90 c3g1wB_ not modelled 38.3 11 PDB header:transport protein Chain: B: PDB Molecule:sugar abc transporter; PDBTitle: crystal structure of sugar abc transporter (sugar-binding protein)2 from bacillus halodurans 91 d1xwaa_ not modelled 38.2 14 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase 92 d1lbqa_ not modelled 37.7 16 Fold:Chelatase-like Superfamily:Chelatase Family:Ferrochelatase 93 c3h7uA_ not modelled 37.7 19 PDB header:oxidoreductase Chain: A: PDB Molecule:aldo-keto reductase; PDBTitle: crystal structure of the plant stress-response enzyme akr4c9 94 c3cvjB_ not modelled 37.5 24 PDB header:isomerase Chain: B: PDB Molecule:putative phosphoheptose isomerase; PDBTitle: crystal structure of a putative phosphoheptose isomerase (bh3325) from2 bacillus halodurans c-125 at 2.00 a resolution 95 c3fn9B_ not modelled 37.0 15 PDB header:hydrolase Chain: B: PDB Molecule:putative beta-galactosidase; PDBTitle: crystal structure of putative beta-galactosidase from bacteroides2 fragilis 96 c3hz4A_ not modelled 36.9 18 PDB header:oxidoreductase Chain: A: PDB Molecule:thioredoxin; PDBTitle: crystal structure of thioredoxin from methanosarcina mazei 97 c2xhzC_ not modelled 36.3 14 PDB header:isomerase Chain: C: PDB Molecule:arabinose 5-phosphate isomerase; PDBTitle: probing the active site of the sugar isomerase domain from e. coli2 arabinose-5-phosphate isomerase via x-ray crystallography 98 d2f48a1 not modelled 35.8 18 Fold:Phosphofructokinase Superfamily:Phosphofructokinase Family:Phosphofructokinase 99 d4pfka_ not modelled 35.4 11 Fold:Phosphofructokinase Superfamily:Phosphofructokinase Family:Phosphofructokinase 100 c3lkbB_ not modelled 35.1 15 PDB header:transport protein Chain: B: PDB Molecule:probable branched-chain amino acid abc PDBTitle: crystal structure of a branched chain amino acid abc2 transporter from thermus thermophilus with bound valine 101 c3koxA_ not modelled 34.8 15 PDB header:metal binding protein Chain: A: PDB Molecule:d-ornithine aminomutase e component; PDBTitle: crystal structure of ornithine 4,5 aminomutase in complex with 2,4-2 diaminobutyrate (anaerobic) 102 d1vp5a_ not modelled 34.1 20 Fold:TIM beta/alpha-barrel Superfamily:NAD(P)-linked oxidoreductase Family:Aldo-keto reductases (NADP) 103 c3p3wC_ not modelled 33.9 13 PDB header:transport protein Chain: C: PDB Molecule:glutamate receptor 3; PDBTitle: structure of a dimeric glua3 n-terminal domain (ntd) at 4.2 a2 resolution 104 c3glsC_ not modelled 33.7 24 PDB header:hydrolase Chain: C: PDB Molecule:nad-dependent deacetylase sirtuin-3, PDBTitle: crystal structure of human sirt3 105 c3mn1B_ not modelled 33.5 14 PDB header:hydrolase Chain: B: PDB Molecule:probable yrbi family phosphatase; PDBTitle: crystal structure of probable yrbi family phosphatase from pseudomonas2 syringae pv.phaseolica 1448a 106 d1vhca_ not modelled 33.4 16 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 107 d1thxa_ not modelled 32.9 14 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase 108 c3ngjC_ not modelled 32.7 14 PDB header:lyase Chain: C: PDB Molecule:deoxyribose-phosphate aldolase; PDBTitle: crystal structure of a putative deoxyribose-phosphate aldolase from2 entamoeba histolytica 109 c3s99A_ not modelled 32.7 9 PDB header:lipid binding protein Chain: A: PDB Molecule:basic membrane lipoprotein; PDBTitle: crystal structure of a basic membrane lipoprotein from brucella2 melitensis, iodide soak 110 c2r8zC_ not modelled 32.7 9 PDB header:hydrolase Chain: C: PDB Molecule:3-deoxy-d-manno-octulosonate 8-phosphate phosphatase; PDBTitle: crystal structure of yrbi phosphatase from escherichia coli in complex2 with a phosphate and a calcium ion 111 c3p2yA_ not modelled 32.6 22 PDB header:oxidoreductase Chain: A: PDB Molecule:alanine dehydrogenase/pyridine nucleotide transhydrogenase; PDBTitle: crystal structure of alanine dehydrogenase/pyridine nucleotide2 transhydrogenase from mycobacterium smegmatis 112 c3cmgA_ not modelled 32.4 13 PDB header:hydrolase Chain: A: PDB Molecule:putative beta-galactosidase; PDBTitle: crystal structure of putative beta-galactosidase from bacteroides2 fragilis 113 d1nria_ not modelled 32.0 15 Fold:SIS domain Superfamily:SIS domain Family:mono-SIS domain 114 c1nriA_ not modelled 32.0 15 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein hi0754; PDBTitle: crystal structure of putative phosphosugar isomerase hi0754 from2 haemophilus influenzae 115 d1pfka_ not modelled 31.9 14 Fold:Phosphofructokinase Superfamily:Phosphofructokinase Family:Phosphofructokinase 116 c1h6zA_ not modelled 31.7 9 PDB header:transferase Chain: A: PDB Molecule:pyruvate phosphate dikinase; PDBTitle: 3.0 a resolution crystal structure of glycosomal pyruvate2 phosphate dikinase from trypanosoma brucei 117 c3cyvA_ not modelled 31.6 18 PDB header:lyase Chain: A: PDB Molecule:uroporphyrinogen decarboxylase; PDBTitle: crystal structure of uroporphyrinogen decarboxylase from2 shigella flexineri: new insights into its catalytic3 mechanism 118 d1z2wa1 not modelled 31.4 14 Fold:Metallo-dependent phosphatases Superfamily:Metallo-dependent phosphatases Family:YfcE-like 119 d1o5za1 not modelled 31.3 23 Fold:MurD-like peptide ligases, peptide-binding domain Superfamily:MurD-like peptide ligases, peptide-binding domain Family:Folylpolyglutamate synthetase, C-terminal domain 120 d2alra_ not modelled 31.3 19 Fold:TIM beta/alpha-barrel Superfamily:NAD(P)-linked oxidoreductase Family:Aldo-keto reductases (NADP)

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0