Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP23842
DateThu Jan 5 11:39:48 GMT 2012
Unique Job ID1e8994c8d0037871

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c3pjwA_
Top template information
PDB header:lyase
Chain: A: PDB Molecule:cyclic dimeric gmp binding protein;
PDBTitle: structure of pseudomonas fluorescence lapd ggdef-eal dual domain, i23
Confidence and coverage
Confidence:100.0% Coverage: 55%
403 residues ( 55% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MFVEHNLIKNIKIFTLAFTLTVVLIQLSRFISPLAIIHSSYIFLAWMPLCVMLSILFIFG
Secondary structure 








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   .........70.........80.........90.........100.........110.........120
Sequence  WRGVVPVLCGMFCTNLWNFHLSFLQTAVMLGSQTFVVLCACAILRWQLGTRWRYGLTSRY
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?
??
??????
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   .........130.........140.........150.........160.........170.........180
Sequence  VWQRLFWLGLVTPIGIKCSMYLVGSFFDFPLKISTFFGDADAIFTVVDLLSLFTAVLIYN
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   .........190.........200.........210.........220.........230.........240
Sequence  MLFYYLTRMIVSPHFAQILWRRDIAPSLGKEKRAFTLSWLAALSVLLLLLCTPYENDFIA
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??
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   .........250.........260.........270.........280.........290.........300
Sequence  GYLVPVFFIIFTLGVGKLRYPFLNLTWAVSTLCLLNYNQNFLQGVETEYSLAFILAVLIS
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???
??
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   .........310.........320.........330.........340.........350.........360
Sequence  FSVCLLYMVRIYHRSEWLNRRWHLQALTDPLTLLPNFRALEQAPEQEAGKSFCCLRIDNL
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   .........370.........380.........390.........400.........410.........420
Sequence  EFMSRHYGLMMRVHCIRSICRTLLPLMQENEKLYQLPGSELLLVLSGPETEGRLQHMVNI
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   .........430.........440.........450.........460.........470.........480
Sequence  LNSRQIHWNNTGLDMGYGAAWGRFDGNQETLQPLLGQLSWLAEQSCAHHHVLALDSREEM
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   .........490.........500.........510.........520.........530.........540
Sequence  VSGQTTKQVLLLNTIRTALDQGDLLLYAQPIRNKEGEGYDEILARLKYDGGIMTPDKFLP
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   .........550.........560.........570.........580.........590.........600
Sequence  LIAQFNLSARFDLQVLESLLKWLATHPCDKKGPRFSVNLMPLTLLQKNIAGRIIRLFKRY
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   .........610.........620.........630.........640.........650.........660
Sequence  HISPQAVILEITEEQAFSNAESSMYNIEQLHKFGFRIAIDDFGTGYANYERLKRLQADII
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   .........670.........680.........690.........700.........710.........720
Sequence  KIDGVFVKDIVTNTLDAMIVRSITDLAKAKSLSVVAEFVETQQQQALLHKLGVQYLQGYL
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   .........
Sequence  IGRPQPLAD
Secondary structure 







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Disorder 




????
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 3pjw chain A

3D model

Region: 310 - 726
Aligned: 403
Modelled: 417
Confidence: 100.0%
Identity: 21%
PDB header:lyase
Chain: A: PDB Molecule:cyclic dimeric gmp binding protein;
PDBTitle: structure of pseudomonas fluorescence lapd ggdef-eal dual domain, i23

Phyre2

PDB 3gfz chain B

3D model

Region: 322 - 725
Aligned: 362
Modelled: 379
Confidence: 100.0%
Identity: 20%
PDB header:hydrolase, signaling protein
Chain: B: PDB Molecule:klebsiella pneumoniae blrp1;
PDBTitle: klebsiella pneumoniae blrp1 ph 6 manganese/cy-digmp complex

Phyre2

PDB 3hvb chain B

3D model

Region: 487 - 729
Aligned: 242
Modelled: 243
Confidence: 100.0%
Identity: 24%
PDB header:hydrolase
Chain: B: PDB Molecule:protein fimx;
PDBTitle: crystal structure of the dual-domain ggdef-eal module of2 fimx from pseudomonas aeruginosa

Phyre2

PDB 3hv9 chain A

3D model

Region: 477 - 729
Aligned: 252
Modelled: 253
Confidence: 100.0%
Identity: 23%
PDB header:hydrolase
Chain: A: PDB Molecule:protein fimx;
PDBTitle: crystal structure of fimx eal domain from pseudomonas aeruginosa

Phyre2

PDB 3s83 chain A

3D model

Region: 491 - 729
Aligned: 236
Modelled: 239
Confidence: 100.0%
Identity: 29%
PDB header:signaling protein
Chain: A: PDB Molecule:ggdef family protein;
PDBTitle: crystal structure of eal domain from caulobacter crescentus cb15

Phyre2

PDB 3pfm chain A

3D model

Region: 486 - 726
Aligned: 235
Modelled: 241
Confidence: 100.0%
Identity: 26%
PDB header:signaling protein
Chain: A: PDB Molecule:ggdef domain protein;
PDBTitle: crystal structure of a eal domain of ggdef domain protein from2 pseudomonas fluorescens pf

Phyre2

PDB 2w27 chain A

3D model

Region: 494 - 726
Aligned: 225
Modelled: 233
Confidence: 100.0%
Identity: 22%
PDB header:signaling protein
Chain: A: PDB Molecule:ykui protein;
PDBTitle: crystal structure of the bacillus subtilis ykui protein,2 with an eal domain, in complex with substrate c-di-gmp and3 calcium

Phyre2

PDB 2bas chain A domain 1

3D model

Region: 494 - 726
Aligned: 228
Modelled: 233
Confidence: 100.0%
Identity: 21%
Fold: TIM beta/alpha-barrel
Superfamily: EAL domain-like
Family: EAL domain

Phyre2

PDB 2r6o chain B

3D model

Region: 490 - 729
Aligned: 228
Modelled: 240
Confidence: 100.0%
Identity: 30%
PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:putative diguanylate cyclase/phosphodiesterase (ggdef & eal
PDBTitle: crystal structure of putative diguanylate cyclase/phosphodiesterase2 from thiobacillus denitrificans

Phyre2

PDB 3kzp chain A

3D model

Region: 503 - 727
Aligned: 221
Modelled: 224
Confidence: 100.0%
Identity: 25%
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:putative diguanylate cyclase/phosphodiesterase;
PDBTitle: crystal structure of putative diguanylate cyclase/phosphodiesterase2 from listaria monocytigenes

Phyre2

PDB 1w25 chain B

3D model

Region: 295 - 474
Aligned: 180
Modelled: 180
Confidence: 100.0%
Identity: 14%
PDB header:signaling protein
Chain: B: PDB Molecule:stalked-cell differentiation controlling protein;
PDBTitle: response regulator pled in complex with c-digmp

Phyre2

PDB 3ezu chain A

3D model

Region: 301 - 474
Aligned: 168
Modelled: 174
Confidence: 100.0%
Identity: 10%
PDB header:signaling protein
Chain: A: PDB Molecule:ggdef domain protein;
PDBTitle: crystal structure of multidomain protein of unknown function with2 ggdef-domain (np_951600.1) from geobacter sulfurreducens at 1.95 a3 resolution

Phyre2

PDB 3bre chain A

3D model

Region: 287 - 478
Aligned: 192
Modelled: 192
Confidence: 99.9%
Identity: 14%
PDB header:signaling protein
Chain: A: PDB Molecule:probable two-component response regulator;
PDBTitle: crystal structure of p.aeruginosa pa3702

Phyre2

PDB 3i5c chain A

3D model

Region: 308 - 474
Aligned: 167
Modelled: 167
Confidence: 99.9%
Identity: 16%
PDB header:signaling protein
Chain: A: PDB Molecule:fusion of general control protein gcn4 and wspr response
PDBTitle: crystal structure of a fusion protein containing the leucine zipper of2 gcn4 and the ggdef domain of wspr from pseudomonas aeruginosa

Phyre2

PDB 3mtk chain A

3D model

Region: 321 - 478
Aligned: 153
Modelled: 158
Confidence: 99.9%
Identity: 14%
PDB header:transferase
Chain: A: PDB Molecule:diguanylate cyclase/phosphodiesterase;
PDBTitle: x-ray structure of diguanylate cyclase/phosphodiesterase from2 caldicellulosiruptor saccharolyticus, northeast structural genomics3 consortium target clr27c

Phyre2

PDB 3ign chain A

3D model

Region: 324 - 475
Aligned: 152
Modelled: 148
Confidence: 99.9%
Identity: 13%
PDB header:transferase
Chain: A: PDB Molecule:diguanylate cyclase;
PDBTitle: crystal structure of the ggdef domain from marinobacter2 aquaeolei diguanylate cyclase complexed with c-di-gmp -3 northeast structural genomics consortium target mqr89a

Phyre2

PDB 3i5b chain A

3D model

Region: 325 - 478
Aligned: 153
Modelled: 154
Confidence: 99.9%
Identity: 18%
PDB header:signaling protein
Chain: A: PDB Molecule:wspr response regulator;
PDBTitle: crystal structure of the isolated ggdef domain of wpsr from2 pseudomonas aeruginosa

Phyre2

PDB 3icl chain A

3D model

Region: 328 - 478
Aligned: 151
Modelled: 150
Confidence: 99.9%
Identity: 12%
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:eal/ggdef domain protein;
PDBTitle: x-ray structure of protein (eal/ggdef domain protein) from2 m.capsulatus, northeast structural genomics consortium3 target mcr174c

Phyre2

PDB 3hva chain A

3D model

Region: 325 - 475
Aligned: 151
Modelled: 151
Confidence: 99.9%
Identity: 13%
PDB header:transferase
Chain: A: PDB Molecule:protein fimx;
PDBTitle: crystal structure of fimx ggdef domain from pseudomonas2 aeruginosa

Phyre2

PDB 3i5a chain A

3D model

Region: 286 - 474
Aligned: 188
Modelled: 189
Confidence: 99.9%
Identity: 11%
PDB header:signaling protein
Chain: A: PDB Molecule:response regulator/ggdef domain protein;
PDBTitle: crystal structure of full-length wpsr from pseudomonas syringae

Phyre2
1

c3pjwA_
2

c3gfzB_
3

c3hvbB_
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c3hv9A_
5

c3s83A_
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c3pfmA_
7

c2w27A_
8

d2basa1
9

c2r6oB_
10

c3kzpA_
11

c1w25B_
12

c3ezuA_
13

c3breA_
14

c3i5cA_
15

c3mtkA_
16

c3ignA_
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c3i5bA_
18

c3iclA_
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c3hvaA_
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c3i5aA_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c3pjwA_



100.0 21 PDB header:lyase
Chain: A: PDB Molecule:cyclic dimeric gmp binding protein;
PDBTitle: structure of pseudomonas fluorescence lapd ggdef-eal dual domain, i23
2c3gfzB_



100.0 20 PDB header:hydrolase, signaling protein
Chain: B: PDB Molecule:klebsiella pneumoniae blrp1;
PDBTitle: klebsiella pneumoniae blrp1 ph 6 manganese/cy-digmp complex
3c3hvbB_



100.0 24 PDB header:hydrolase
Chain: B: PDB Molecule:protein fimx;
PDBTitle: crystal structure of the dual-domain ggdef-eal module of2 fimx from pseudomonas aeruginosa
4c3hv9A_



100.0 23 PDB header:hydrolase
Chain: A: PDB Molecule:protein fimx;
PDBTitle: crystal structure of fimx eal domain from pseudomonas aeruginosa
5c3s83A_



100.0 29 PDB header:signaling protein
Chain: A: PDB Molecule:ggdef family protein;
PDBTitle: crystal structure of eal domain from caulobacter crescentus cb15
6c3pfmA_



100.0 26 PDB header:signaling protein
Chain: A: PDB Molecule:ggdef domain protein;
PDBTitle: crystal structure of a eal domain of ggdef domain protein from2 pseudomonas fluorescens pf
7c2w27A_



100.0 22 PDB header:signaling protein
Chain: A: PDB Molecule:ykui protein;
PDBTitle: crystal structure of the bacillus subtilis ykui protein,2 with an eal domain, in complex with substrate c-di-gmp and3 calcium
8d2basa1



100.0 21 Fold:TIM beta/alpha-barrel
Superfamily:EAL domain-like
Family:EAL domain
9c2r6oB_



100.0 30 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:putative diguanylate cyclase/phosphodiesterase (ggdef & eal
PDBTitle: crystal structure of putative diguanylate cyclase/phosphodiesterase2 from thiobacillus denitrificans
10c3kzpA_



100.0 25 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:putative diguanylate cyclase/phosphodiesterase;
PDBTitle: crystal structure of putative diguanylate cyclase/phosphodiesterase2 from listaria monocytigenes
11c1w25B_



100.0 14 PDB header:signaling protein
Chain: B: PDB Molecule:stalked-cell differentiation controlling protein;
PDBTitle: response regulator pled in complex with c-digmp
12c3ezuA_



100.0 10 PDB header:signaling protein
Chain: A: PDB Molecule:ggdef domain protein;
PDBTitle: crystal structure of multidomain protein of unknown function with2 ggdef-domain (np_951600.1) from geobacter sulfurreducens at 1.95 a3 resolution
13c3breA_



99.9 14 PDB header:signaling protein
Chain: A: PDB Molecule:probable two-component response regulator;
PDBTitle: crystal structure of p.aeruginosa pa3702
14c3i5cA_



99.9 16 PDB header:signaling protein
Chain: A: PDB Molecule:fusion of general control protein gcn4 and wspr response
PDBTitle: crystal structure of a fusion protein containing the leucine zipper of2 gcn4 and the ggdef domain of wspr from pseudomonas aeruginosa
15c3mtkA_



99.9 14 PDB header:transferase
Chain: A: PDB Molecule:diguanylate cyclase/phosphodiesterase;
PDBTitle: x-ray structure of diguanylate cyclase/phosphodiesterase from2 caldicellulosiruptor saccharolyticus, northeast structural genomics3 consortium target clr27c
16c3ignA_



99.9 13 PDB header:transferase
Chain: A: PDB Molecule:diguanylate cyclase;
PDBTitle: crystal structure of the ggdef domain from marinobacter2 aquaeolei diguanylate cyclase complexed with c-di-gmp -3 northeast structural genomics consortium target mqr89a
17c3i5bA_



99.9 18 PDB header:signaling protein
Chain: A: PDB Molecule:wspr response regulator;
PDBTitle: crystal structure of the isolated ggdef domain of wpsr from2 pseudomonas aeruginosa
18c3iclA_



99.9 12 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:eal/ggdef domain protein;
PDBTitle: x-ray structure of protein (eal/ggdef domain protein) from2 m.capsulatus, northeast structural genomics consortium3 target mcr174c
19c3hvaA_



99.9 13 PDB header:transferase
Chain: A: PDB Molecule:protein fimx;
PDBTitle: crystal structure of fimx ggdef domain from pseudomonas2 aeruginosa
20c3i5aA_



99.9 11 PDB header:signaling protein
Chain: A: PDB Molecule:response regulator/ggdef domain protein;
PDBTitle: crystal structure of full-length wpsr from pseudomonas syringae
21c3qyyB_



not modelled 99.9 16 PDB header:signaling protein/inhibitor
Chain: B: PDB Molecule:response regulator;
PDBTitle: a novel interaction mode between a microbial ggdef domain and the bis-2 (3, 5 )-cyclic di-gmp
22d1w25a3



not modelled 99.9 16 Fold:Ferredoxin-like
Superfamily:Nucleotide cyclase
Family:GGDEF domain
23c3hvwA_



not modelled 99.7 13 PDB header:lyase
Chain: A: PDB Molecule:diguanylate-cyclase (dgc);
PDBTitle: crystal structure of the ggdef domain of the pa2567 protein2 from pseudomonas aeruginosa, northeast structural genomics3 consortium target par365c
24c3p7nB_



not modelled 97.6 9 PDB header:dna binding protein
Chain: B: PDB Molecule:sensor histidine kinase;
PDBTitle: crystal structure of light activated transcription factor el222 from2 erythrobacter litoralis
25c3khtA_



not modelled 94.1 8 PDB header:signaling protein
Chain: A: PDB Molecule:response regulator;
PDBTitle: crystal structure of response regulator from hahella chejuensis
26d1mvoa_



not modelled 92.4 10 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
27d1p6qa_



not modelled 92.3 12 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
28d1gjwa2



not modelled 92.1 11 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:Amylase, catalytic domain
29c2qv6D_



not modelled 91.9 12 PDB header:hydrolase
Chain: D: PDB Molecule:gtp cyclohydrolase iii;
PDBTitle: gtp cyclohydrolase iii from m. jannaschii (mj0145)2 complexed with gtp and metal ions
30c2zayA_



not modelled 91.7 17 PDB header:signaling protein
Chain: A: PDB Molecule:response regulator receiver protein;
PDBTitle: crystal structure of response regulator from desulfuromonas2 acetoxidans
31c2pz0B_



not modelled 91.2 14 PDB header:hydrolase
Chain: B: PDB Molecule:glycerophosphoryl diester phosphodiesterase;
PDBTitle: crystal structure of glycerophosphodiester phosphodiesterase (gdpd)2 from t. tengcongensis
32c3gt7A_



not modelled 90.5 12 PDB header:hydrolase
Chain: A: PDB Molecule:sensor protein;
PDBTitle: crystal structure of signal receiver domain of signal2 transduction histidine kinase from syntrophus3 aciditrophicus
33c2c3zA_



not modelled 90.2 19 PDB header:lyase
Chain: A: PDB Molecule:indole-3-glycerol phosphate synthase;
PDBTitle: crystal structure of a truncated variant of indole-3-2 glycerol phosphate synthase from sulfolobus solfataricus
34d1ua7a2



not modelled 89.9 12 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:Amylase, catalytic domain
35d1a53a_



not modelled 89.7 20 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
36c2p0oA_



not modelled 88.6 12 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:hypothetical protein duf871;
PDBTitle: crystal structure of a conserved protein from locus ef_2437 in2 enterococcus faecalis with an unknown function
37c3q58A_



not modelled 88.4 15 PDB header:isomerase
Chain: A: PDB Molecule:n-acetylmannosamine-6-phosphate 2-epimerase;
PDBTitle: structure of n-acetylmannosamine-6-phosphate epimerase from salmonella2 enterica
38d1jbea_



not modelled 88.3 13 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
39c2h6rG_



not modelled 88.1 15 PDB header:isomerase
Chain: G: PDB Molecule:triosephosphate isomerase;
PDBTitle: crystal structure of triosephosphate isomerase (tim) from2 methanocaldococcus jannaschii
40c3qvqB_



not modelled 88.1 17 PDB header:hydrolase
Chain: B: PDB Molecule:phosphodiesterase olei02445;
PDBTitle: the structure of an oleispira antarctica phosphodiesterase olei024452 in complex with the product sn-glycerol-3-phosphate
41c3t8yA_



not modelled 88.0 16 PDB header:hydrolase
Chain: A: PDB Molecule:chemotaxis response regulator protein-glutamate
PDBTitle: crystal structure of the response regulator domain of thermotoga2 maritima cheb
42c3nhzA_



not modelled 87.9 17 PDB header:dna binding protein
Chain: A: PDB Molecule:two component system transcriptional regulator mtra;
PDBTitle: structure of n-terminal domain of mtra
43c1cygA_



not modelled 87.5 22 PDB header:glycosyltransferase
Chain: A: PDB Molecule:cyclodextrin glucanotransferase;
PDBTitle: cyclodextrin glucanotransferase (e.c.2.4.1.19) (cgtase)
44d1bf2a3



not modelled 87.5 10 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:Amylase, catalytic domain
45c3hebB_



not modelled 87.5 15 PDB header:transcription regulator
Chain: B: PDB Molecule:response regulator receiver domain protein (chey);
PDBTitle: crystal structure of response regulator receiver domain from2 rhodospirillum rubrum
46d1vhna_



not modelled 87.3 14 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
47c1qhoA_



not modelled 87.3 19 PDB header:hydrolase
Chain: A: PDB Molecule:alpha-amylase;
PDBTitle: five-domain alpha-amylase from bacillus stearothermophilus,2 maltose/acarbose complex
48d1y0ea_



not modelled 86.9 13 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:NanE-like
49c3kruC_



not modelled 86.8 17 PDB header:oxidoreductase
Chain: C: PDB Molecule:nadh:flavin oxidoreductase/nadh oxidase;
PDBTitle: crystal structure of the thermostable old yellow enzyme from2 thermoanaerobacter pseudethanolicus e39
50d1u0sy_



not modelled 86.7 18 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
51c1m53A_



not modelled 86.7 12 PDB header:isomerase
Chain: A: PDB Molecule:isomaltulose synthase;
PDBTitle: crystal structure of isomaltulose synthase (pali) from2 klebsiella sp. lx3
52c3a47A_



not modelled 86.5 12 PDB header:hydrolase
Chain: A: PDB Molecule:oligo-1,6-glucosidase;
PDBTitle: crystal structure of isomaltase from saccharomyces cerevisiae
53d2pl1a1



not modelled 86.5 16 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
54c2rjnA_



not modelled 86.5 11 PDB header:hydrolase
Chain: A: PDB Molecule:response regulator receiver:metal-dependent
PDBTitle: crystal structure of an uncharacterized protein q2bku2 from2 neptuniibacter caesariensis
55c3edeB_



not modelled 86.2 12 PDB header:hydrolase
Chain: B: PDB Molecule:cyclomaltodextrinase;
PDBTitle: structural base for cyclodextrin hydrolysis
56c3b2nA_



not modelled 86.0 7 PDB header:transcription
Chain: A: PDB Molecule:uncharacterized protein q99uf4;
PDBTitle: crystal structure of dna-binding response regulator, luxr family, from2 staphylococcus aureus
57d1krwa_



not modelled 86.0 11 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
58d1m7xa3



not modelled 85.6 20 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:Amylase, catalytic domain
59c3i42A_



not modelled 85.5 17 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:response regulator receiver domain protein (chey-
PDBTitle: structure of response regulator receiver domain (chey-like)2 from methylobacillus flagellatus
60c2jk1A_



not modelled 85.5 9 PDB header:dna-binding
Chain: A: PDB Molecule:hydrogenase transcriptional regulatory protein hupr1;
PDBTitle: crystal structure of the wild-type hupr receiver domain
61d1dz3a_



not modelled 85.1 17 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
62c3gr7A_



not modelled 85.1 12 PDB header:oxidoreductase
Chain: A: PDB Molecule:nadph dehydrogenase;
PDBTitle: structure of oye from geobacillus kaustophilus, hexagonal2 crystal form
63c1gjuA_



not modelled 84.9 12 PDB header:transferase
Chain: A: PDB Molecule:maltodextrin glycosyltransferase;
PDBTitle: maltosyltransferase from thermotoga maritima
64c3q94B_



not modelled 84.6 18 PDB header:lyase
Chain: B: PDB Molecule:fructose-bisphosphate aldolase, class ii;
PDBTitle: the crystal structure of fructose 1,6-bisphosphate aldolase from2 bacillus anthracis str. 'ames ancestor'
65d1m53a2



not modelled 84.5 14 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:Amylase, catalytic domain
66c1bagA_



not modelled 84.4 11 PDB header:alpha-amylase
Chain: A: PDB Molecule:alpha-1,4-glucan-4-glucanohydrolase;
PDBTitle: alpha-amylase from bacillus subtilis complexed with2 maltopentaose
67c2ayxA_



not modelled 84.3 14 PDB header:transferase
Chain: A: PDB Molecule:sensor kinase protein rcsc;
PDBTitle: solution structure of the e.coli rcsc c-terminus (residues2 700-949) containing linker region and phosphoreceiver3 domain
68d1h3ga3



not modelled 84.1 12 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:Amylase, catalytic domain
69d1w25a1



not modelled 83.8 13 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
70d2guya2



not modelled 83.6 12 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:Amylase, catalytic domain
71c1zjaB_



not modelled 83.5 10 PDB header:isomerase
Chain: B: PDB Molecule:trehalulose synthase;
PDBTitle: crystal structure of the trehalulose synthase mutb from2 pseudomonas mesoacidophila mx-45 (triclinic form)
72d1yioa2



not modelled 83.3 12 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
73c1gcyA_



not modelled 83.2 13 PDB header:hydrolase
Chain: A: PDB Molecule:glucan 1,4-alpha-maltotetrahydrolase;
PDBTitle: high resolution crystal structure of maltotetraose-forming2 exo-amylase
74c2ze0A_



not modelled 83.1 17 PDB header:hydrolase
Chain: A: PDB Molecule:alpha-glucosidase;
PDBTitle: alpha-glucosidase gsj
75c3gl9B_



not modelled 83.0 18 PDB header:signaling protein
Chain: B: PDB Molecule:response regulator;
PDBTitle: the structure of a histidine kinase-response regulator2 complex sheds light into two-component signaling and3 reveals a novel cis autophosphorylation mechanism
76d1w0ma_



not modelled 82.9 16 Fold:TIM beta/alpha-barrel
Superfamily:Triosephosphate isomerase (TIM)
Family:Triosephosphate isomerase (TIM)
77c2ya0A_



not modelled 82.8 11 PDB header:hydrolase
Chain: A: PDB Molecule:putative alkaline amylopullulanase;
PDBTitle: catalytic module of the multi-modular glycogen-degrading2 pneumococcal virulence factor spua
78c3czkA_



not modelled 82.3 15 PDB header:hydrolase
Chain: A: PDB Molecule:sucrose hydrolase;
PDBTitle: crystal structure analysis of sucrose hydrolase(suh) e322q-2 sucrose complex
79d2bhua3



not modelled 82.3 17 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:Amylase, catalytic domain
80d1g5aa2



not modelled 82.2 13 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:Amylase, catalytic domain
81d1a04a2



not modelled 82.1 12 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
82c1cjkA_



not modelled 82.0 15 PDB header:lyase/lyase/signaling protein
Chain: A: PDB Molecule:adenylate cyclase, type v;
PDBTitle: complex of gs-alpha with the catalytic domains of mammalian adenylyl2 cyclase: complex with adenosine 5'-(alpha thio)-triphosphate (rp),3 mg, and mn
83d1eh9a3



not modelled 81.9 20 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:Amylase, catalytic domain
84c3faxA_



not modelled 81.7 13 PDB header:hydrolase
Chain: A: PDB Molecule:reticulocyte binding protein;
PDBTitle: the crystal structure of gbs pullulanase sap in complex with2 maltotetraose
85c2qr3A_



not modelled 81.6 8 PDB header:transcription
Chain: A: PDB Molecule:two-component system response regulator;
PDBTitle: crystal structure of the n-terminal signal receiver domain of two-2 component system response regulator from bacteroides fragilis
86d1heya_



not modelled 81.5 16 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
87c2wcsA_



not modelled 81.3 17 PDB header:hydrolase
Chain: A: PDB Molecule:alpha amylase, catalytic region;
PDBTitle: crystal structure of debranching enzyme from nostoc2 punctiforme (npde)
88d1dbwa_



not modelled 81.1 14 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
89d2aaaa2



not modelled 80.6 18 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:Amylase, catalytic domain
90d1lwha2



not modelled 80.6 11 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:Amylase, catalytic domain
91c3ch0A_



not modelled 80.3 24 PDB header:hydrolase
Chain: A: PDB Molecule:glycerophosphodiester phosphodiesterase;
PDBTitle: crystal structure of glycerophosphoryl diester phosphodiesterase2 (yp_677622.1) from cytophaga hutchinsonii atcc 33406 at 1.50 a3 resolution
92c3igsB_



not modelled 80.2 15 PDB header:isomerase
Chain: B: PDB Molecule:n-acetylmannosamine-6-phosphate 2-epimerase 2;
PDBTitle: structure of the salmonella enterica n-acetylmannosamine-6-phosphate2 2-epimerase
93d2r25b1



not modelled 80.2 14 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
94d1uoka2



not modelled 80.2 14 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:Amylase, catalytic domain
95d1ny5a1



not modelled 80.1 15 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
96c3dhuC_



not modelled 80.1 23 PDB header:hydrolase
Chain: C: PDB Molecule:alpha-amylase;
PDBTitle: crystal structure of an alpha-amylase from lactobacillus2 plantarum
97d1qhoa4



not modelled 80.0 18 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:Amylase, catalytic domain
98c1tcmB_



not modelled 80.0 16 PDB header:glycosyltransferase
Chain: B: PDB Molecule:cyclodextrin glycosyltransferase;
PDBTitle: cyclodextrin glycosyltransferase w616a mutant from bacillus2 circulans strain 251
99c3crnA_



not modelled 79.6 10 PDB header:signaling protein
Chain: A: PDB Molecule:response regulator receiver domain protein, chey-like;
PDBTitle: crystal structure of response regulator receiver domain protein (chey-2 like) from methanospirillum hungatei jf-1
100c1jibA_



not modelled 79.3 21 PDB header:hydrolase
Chain: A: PDB Molecule:neopullulanase;
PDBTitle: complex of alpha-amylase ii (tva ii) from thermoactinomyces2 vulgaris r-47 with maltotetraose based on a crystal soaked3 with maltohexaose.
101c3eulB_



not modelled 79.2 11 PDB header:transcription
Chain: B: PDB Molecule:possible nitrate/nitrite response transcriptional
PDBTitle: structure of the signal receiver domain of the putative2 response regulator narl from mycobacterium tuberculosis
102d1gcya2



not modelled 79.0 14 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:Amylase, catalytic domain
103c3ozbF_



not modelled 79.0 20 PDB header:transferase
Chain: F: PDB Molecule:methylthioadenosine phosphorylase;
PDBTitle: crystal structure of 5'-methylthioinosine phosphorylase from2 psedomonas aeruginosa in complex with hypoxanthine
104c3rlhA_



not modelled 78.8 13 PDB header:hydrolase
Chain: A: PDB Molecule:sphingomyelin phosphodiesterase d lisictox-alphaia1a;
PDBTitle: crystal structure of a class ii phospholipase d from loxosceles2 intermedia venom
105d1ys7a2



not modelled 78.8 13 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
106c1bf2A_



not modelled 78.5 9 PDB header:hydrolase
Chain: A: PDB Molecule:isoamylase;
PDBTitle: structure of pseudomonas isoamylase
107c2e8yA_



not modelled 78.4 15 PDB header:hydrolase
Chain: A: PDB Molecule:amyx protein;
PDBTitle: crystal structure of pullulanase type i from bacillus subtilis str.2 168
108d2ayxa1



not modelled 78.4 14 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
109c3cg0A_



not modelled 78.3 11 PDB header:lyase
Chain: A: PDB Molecule:response regulator receiver modulated diguanylate cyclase
PDBTitle: crystal structure of signal receiver domain of modulated diguanylate2 cyclase from desulfovibrio desulfuricans g20, an example of alternate3 folding
110d1nvma2



not modelled 78.2 10 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:HMGL-like
111c3c97A_



not modelled 77.9 15 PDB header:signaling protein, transferase
Chain: A: PDB Molecule:signal transduction histidine kinase;
PDBTitle: crystal structure of the response regulator receiver domain2 of a signal transduction histidine kinase from aspergillus3 oryzae
112d1ea9c3



not modelled 77.7 20 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:Amylase, catalytic domain
113c2ya1A_



not modelled 77.4 11 PDB header:hydrolase
Chain: A: PDB Molecule:putative alkaline amylopullulanase;
PDBTitle: product complex of a multi-modular glycogen-degrading2 pneumococcal virulence factor spua
114c2zidA_



not modelled 77.4 17 PDB header:hydrolase
Chain: A: PDB Molecule:dextran glucosidase;
PDBTitle: crystal structure of dextran glucosidase e236q complex with2 isomaltotriose
115c2dh3A_



not modelled 77.4 25 PDB header:transport protein, signaling protein
Chain: A: PDB Molecule:4f2 cell-surface antigen heavy chain;
PDBTitle: crystal structure of human ed-4f2hc
116c1jd7A_



not modelled 77.3 9 PDB header:hydrolase
Chain: A: PDB Molecule:alpha-amylase;
PDBTitle: crystal structure analysis of the mutant k300r of2 pseudoalteromonas haloplanctis alpha-amylase
117d1tz9a_



not modelled 77.2 15 Fold:TIM beta/alpha-barrel
Superfamily:Xylose isomerase-like
Family:UxuA-like
118d1cb0a_



not modelled 77.0 11 Fold:Phosphorylase/hydrolase-like
Superfamily:Purine and uridine phosphorylases
Family:Purine and uridine phosphorylases
119d1k66a_



not modelled 77.0 16 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
120c3hf3A_



not modelled 77.0 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:chromate reductase;
PDBTitle: old yellow enzyme from thermus scotoductus sa-01

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Transmembrane helix prediction 

Transmembrane helices have been predicted in your sequence to adopt the topology shown below



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0