Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP75800
DateThu Jan 5 12:14:19 GMT 2012
Unique Job ID111f85dcf90721b4

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c3pjwA_
Top template information
PDB header:lyase
Chain: A: PDB Molecule:cyclic dimeric gmp binding protein;
PDBTitle: structure of pseudomonas fluorescence lapd ggdef-eal dual domain, i23
Confidence and coverage
Confidence:100.0% Coverage: 51%
400 residues ( 51% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
723 residues ( 92%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MLSLYEKIKIRLIILFLLAALSFIGLFFIINYQLVSERAVKRADSRFELIQKNVGYFFKD
Secondary structure 


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   .........70.........80.........90.........100.........110.........120
Sequence  IERSALTLKDSLYLLKNTEEIQRAVILKMEMMPFLDSVGLVLDDNKYYLFSRRANDKIVV
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   .........130.........140.........150.........160.........170.........180
Sequence  YHQEQVNGPLVDESGRVIFADFNPSKRPWSVASDDSNNSWNPAYNCFDRPGKKCISFTLH
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??
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   .........190.........200.........210.........220.........230.........240
Sequence  INGKDHDLLAVDKIHVDLNWRYLNEYLDQISANDEVLFLKQGHEIIAKNQLAREKLIIYN
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   .........250.........260.........270.........280.........290.........300
Sequence  SEGNYNIIDSVDTEYIEKTSAVPNNALFEIYFYYPGGNLLNASDKLFYLPFAFIIIVLLV
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Disorder  ???






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   .........310.........320.........330.........340.........350.........360
Sequence  VYLMTTRVFRRQFSEMTELVNTLAFLPDSTDQIEALKIREGDAKEIISIKNSIAEMKDAE
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   .........370.........380.........390.........400.........410.........420
Sequence  IERSNKLLSLISYDQESGFIKNMAIIESNNNQYLAVGIIKLCGLEAVEAVFGVDERNKIV
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   .........430.........440.........450.........460.........470.........480
Sequence  RKLCQRIAEKYAQCCDIVTFNADLYLLLCRENVQTFTRKIAMVNDFDSSFGYRNLRIHKS
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   .........490.........500.........510.........520.........530.........540
Sequence  AICEPLQGENAWSYAEKLKLAISSIRDHMFSEFIFCDDAKLNEIEENIWIARNIRHAMEI
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   .........550.........560.........570.........580.........590.........600
Sequence  GELFLVYQPIVDINTRAILGAEALCRWVSAERGIISPLKFITIAEDIGFINELGYQIIKT
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   .........610.........620.........630.........640.........650.........660
Sequence  AMGEFRHFSQRASLKDDFLLHINVSPWQLNEPHFHERFTTIMKENGLKANSLCVEITETV
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   .........670.........680.........690.........700.........710.........720
Sequence  IERINEHFYLNIEQLRKQGVRISIDDFGTGLSNLKRFYEINPDSIKVDSQFTGDIFGTAG
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   .........730.........740.........750.........760.........770.........780
Sequence  KIVRIIFDLARYNRIPVIAEGVESEDVARELIKLGCVQAQGYLYQKPMPFSAWDKSGKLV
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   ..
Sequence  KE
Secondary structure 

SS confidence 

Disorder  ??
Disorder confidence 

 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 3pjw chain A

3D model

Region: 356 - 770
Aligned: 400
Modelled: 415
Confidence: 100.0%
Identity: 17%
PDB header:lyase
Chain: A: PDB Molecule:cyclic dimeric gmp binding protein;
PDBTitle: structure of pseudomonas fluorescence lapd ggdef-eal dual domain, i23

Phyre2

PDB 3gfz chain B

3D model

Region: 363 - 773
Aligned: 371
Modelled: 390
Confidence: 100.0%
Identity: 17%
PDB header:hydrolase, signaling protein
Chain: B: PDB Molecule:klebsiella pneumoniae blrp1;
PDBTitle: klebsiella pneumoniae blrp1 ph 6 manganese/cy-digmp complex

Phyre2

PDB 3hvb chain B

3D model

Region: 526 - 774
Aligned: 246
Modelled: 249
Confidence: 100.0%
Identity: 19%
PDB header:hydrolase
Chain: B: PDB Molecule:protein fimx;
PDBTitle: crystal structure of the dual-domain ggdef-eal module of2 fimx from pseudomonas aeruginosa

Phyre2

PDB 3hv9 chain A

3D model

Region: 518 - 774
Aligned: 254
Modelled: 257
Confidence: 100.0%
Identity: 19%
PDB header:hydrolase
Chain: A: PDB Molecule:protein fimx;
PDBTitle: crystal structure of fimx eal domain from pseudomonas aeruginosa

Phyre2

PDB 3s83 chain A

3D model

Region: 530 - 778
Aligned: 246
Modelled: 249
Confidence: 100.0%
Identity: 29%
PDB header:signaling protein
Chain: A: PDB Molecule:ggdef family protein;
PDBTitle: crystal structure of eal domain from caulobacter crescentus cb15

Phyre2

PDB 2w27 chain A

3D model

Region: 533 - 769
Aligned: 228
Modelled: 237
Confidence: 100.0%
Identity: 22%
PDB header:signaling protein
Chain: A: PDB Molecule:ykui protein;
PDBTitle: crystal structure of the bacillus subtilis ykui protein,2 with an eal domain, in complex with substrate c-di-gmp and3 calcium

Phyre2

PDB 3pfm chain A

3D model

Region: 526 - 770
Aligned: 236
Modelled: 245
Confidence: 100.0%
Identity: 22%
PDB header:signaling protein
Chain: A: PDB Molecule:ggdef domain protein;
PDBTitle: crystal structure of a eal domain of ggdef domain protein from2 pseudomonas fluorescens pf

Phyre2

PDB 2bas chain A domain 1

3D model

Region: 533 - 778
Aligned: 240
Modelled: 246
Confidence: 100.0%
Identity: 21%
Fold: TIM beta/alpha-barrel
Superfamily: EAL domain-like
Family: EAL domain

Phyre2

PDB 2r6o chain B

3D model

Region: 528 - 778
Aligned: 235
Modelled: 235
Confidence: 100.0%
Identity: 31%
PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:putative diguanylate cyclase/phosphodiesterase (ggdef & eal
PDBTitle: crystal structure of putative diguanylate cyclase/phosphodiesterase2 from thiobacillus denitrificans

Phyre2

PDB 3kzp chain A

3D model

Region: 542 - 770
Aligned: 221
Modelled: 228
Confidence: 100.0%
Identity: 20%
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:putative diguanylate cyclase/phosphodiesterase;
PDBTitle: crystal structure of putative diguanylate cyclase/phosphodiesterase2 from listaria monocytigenes

Phyre2

PDB 1w25 chain B

3D model

Region: 347 - 517
Aligned: 171
Modelled: 171
Confidence: 100.0%
Identity: 9%
PDB header:signaling protein
Chain: B: PDB Molecule:stalked-cell differentiation controlling protein;
PDBTitle: response regulator pled in complex with c-digmp

Phyre2

PDB 3ezu chain A

3D model

Region: 347 - 515
Aligned: 161
Modelled: 169
Confidence: 100.0%
Identity: 8%
PDB header:signaling protein
Chain: A: PDB Molecule:ggdef domain protein;
PDBTitle: crystal structure of multidomain protein of unknown function with2 ggdef-domain (np_951600.1) from geobacter sulfurreducens at 1.95 a3 resolution

Phyre2

PDB 3bre chain A

3D model

Region: 345 - 518
Aligned: 174
Modelled: 174
Confidence: 99.9%
Identity: 9%
PDB header:signaling protein
Chain: A: PDB Molecule:probable two-component response regulator;
PDBTitle: crystal structure of p.aeruginosa pa3702

Phyre2

PDB 3i5a chain A

3D model

Region: 345 - 514
Aligned: 170
Modelled: 170
Confidence: 99.9%
Identity: 9%
PDB header:signaling protein
Chain: A: PDB Molecule:response regulator/ggdef domain protein;
PDBTitle: crystal structure of full-length wpsr from pseudomonas syringae

Phyre2

PDB 3icl chain A

3D model

Region: 365 - 518
Aligned: 154
Modelled: 154
Confidence: 99.9%
Identity: 12%
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:eal/ggdef domain protein;
PDBTitle: x-ray structure of protein (eal/ggdef domain protein) from2 m.capsulatus, northeast structural genomics consortium3 target mcr174c

Phyre2

PDB 3i5b chain A

3D model

Region: 361 - 517
Aligned: 157
Modelled: 157
Confidence: 99.9%
Identity: 10%
PDB header:signaling protein
Chain: A: PDB Molecule:wspr response regulator;
PDBTitle: crystal structure of the isolated ggdef domain of wpsr from2 pseudomonas aeruginosa

Phyre2

PDB 3qyy chain B

3D model

Region: 359 - 515
Aligned: 153
Modelled: 157
Confidence: 99.9%
Identity: 8%
PDB header:signaling protein/inhibitor
Chain: B: PDB Molecule:response regulator;
PDBTitle: a novel interaction mode between a microbial ggdef domain and the bis-2 (3, 5 )-cyclic di-gmp

Phyre2

PDB 3i5c chain A

3D model

Region: 344 - 515
Aligned: 172
Modelled: 172
Confidence: 99.9%
Identity: 12%
PDB header:signaling protein
Chain: A: PDB Molecule:fusion of general control protein gcn4 and wspr response
PDBTitle: crystal structure of a fusion protein containing the leucine zipper of2 gcn4 and the ggdef domain of wspr from pseudomonas aeruginosa

Phyre2

PDB 3mtk chain A

3D model

Region: 359 - 518
Aligned: 156
Modelled: 160
Confidence: 99.9%
Identity: 12%
PDB header:transferase
Chain: A: PDB Molecule:diguanylate cyclase/phosphodiesterase;
PDBTitle: x-ray structure of diguanylate cyclase/phosphodiesterase from2 caldicellulosiruptor saccharolyticus, northeast structural genomics3 consortium target clr27c

Phyre2

PDB 1w25 chain A domain 3

3D model

Region: 367 - 519
Aligned: 153
Modelled: 153
Confidence: 99.9%
Identity: 11%
Fold: Ferredoxin-like
Superfamily: Nucleotide cyclase
Family: GGDEF domain

Phyre2

PDB 3c8c chain B

3D model

Region: 35 - 288
Aligned: 231
Modelled: 226
Confidence: 99.6%
Identity: 10%
PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:methyl-accepting chemotaxis protein;
PDBTitle: crystal structure of mcp_n and cache domains of methyl-2 accepting chemotaxis protein from vibrio cholerae

Phyre2

PDB 3lic chain A

3D model

Region: 31 - 283
Aligned: 249
Modelled: 247
Confidence: 99.5%
Identity: 11%
PDB header:signaling protein
Chain: A: PDB Molecule:sensor protein;
PDBTitle: crystal structure of the extracellular domain of the putative2 histidine kinase sohk1s-z6

Phyre2

PDB 3lib chain A

3D model

Region: 37 - 287
Aligned: 246
Modelled: 246
Confidence: 99.4%
Identity: 10%
PDB header:signaling protein
Chain: A: PDB Molecule:hypothetical sensory transduction histidine kinase;
PDBTitle: crystal structure of the extracellular domain of the putative2 histidine kinase mmhk1s-z3

Phyre2

PDB 3lia chain A

3D model

Region: 37 - 280
Aligned: 239
Modelled: 239
Confidence: 99.4%
Identity: 13%
PDB header:signaling protein
Chain: A: PDB Molecule:hypothetical sensory transduction histidine kinase;
PDBTitle: crystal structure of the extracellular domain of the putative2 histidine kinase mmhk1s-z2

Phyre2

PDB 2asx chain A domain 1

3D model

Region: 310 - 365
Aligned: 54
Modelled: 54
Confidence: 91.5%
Identity: 19%
Fold: HAMP domain-like
Superfamily: HAMP domain-like
Family: HAMP domain

Phyre2

PDB 3lnr chain A

3D model

Region: 301 - 372
Aligned: 69
Modelled: 69
Confidence: 90.3%
Identity: 13%
PDB header:signaling protein
Chain: A: PDB Molecule:aerotaxis transducer aer2;
PDBTitle: crystal structure of poly-hamp domains from the p. aeruginosa soluble2 receptor aer2

Phyre2
1

c3pjwA_
2

c3gfzB_
3

c3hvbB_
4

c3hv9A_
5

c3s83A_
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c2w27A_
7

c3pfmA_
8

d2basa1
9

c2r6oB_
10

c3kzpA_
11

c1w25B_
12

c3ezuA_
13

c3breA_
14

c3i5aA_
15

c3iclA_
16

c3i5bA_
17

c3qyyB_
18

c3i5cA_
19

c3mtkA_
20

d1w25a3
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c3c8cB_
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c3licA_
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c3libA_
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c3liaA_
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d2asxa1
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c3lnrA_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c3pjwA_



100.0 17 PDB header:lyase
Chain: A: PDB Molecule:cyclic dimeric gmp binding protein;
PDBTitle: structure of pseudomonas fluorescence lapd ggdef-eal dual domain, i23
2c3gfzB_



100.0 17 PDB header:hydrolase, signaling protein
Chain: B: PDB Molecule:klebsiella pneumoniae blrp1;
PDBTitle: klebsiella pneumoniae blrp1 ph 6 manganese/cy-digmp complex
3c3hvbB_



100.0 19 PDB header:hydrolase
Chain: B: PDB Molecule:protein fimx;
PDBTitle: crystal structure of the dual-domain ggdef-eal module of2 fimx from pseudomonas aeruginosa
4c3hv9A_



100.0 19 PDB header:hydrolase
Chain: A: PDB Molecule:protein fimx;
PDBTitle: crystal structure of fimx eal domain from pseudomonas aeruginosa
5c3s83A_



100.0 29 PDB header:signaling protein
Chain: A: PDB Molecule:ggdef family protein;
PDBTitle: crystal structure of eal domain from caulobacter crescentus cb15
6c2w27A_



100.0 22 PDB header:signaling protein
Chain: A: PDB Molecule:ykui protein;
PDBTitle: crystal structure of the bacillus subtilis ykui protein,2 with an eal domain, in complex with substrate c-di-gmp and3 calcium
7c3pfmA_



100.0 22 PDB header:signaling protein
Chain: A: PDB Molecule:ggdef domain protein;
PDBTitle: crystal structure of a eal domain of ggdef domain protein from2 pseudomonas fluorescens pf
8d2basa1



100.0 21 Fold:TIM beta/alpha-barrel
Superfamily:EAL domain-like
Family:EAL domain
9c2r6oB_



100.0 31 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:putative diguanylate cyclase/phosphodiesterase (ggdef & eal
PDBTitle: crystal structure of putative diguanylate cyclase/phosphodiesterase2 from thiobacillus denitrificans
10c3kzpA_



100.0 20 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:putative diguanylate cyclase/phosphodiesterase;
PDBTitle: crystal structure of putative diguanylate cyclase/phosphodiesterase2 from listaria monocytigenes
11c1w25B_



100.0 9 PDB header:signaling protein
Chain: B: PDB Molecule:stalked-cell differentiation controlling protein;
PDBTitle: response regulator pled in complex with c-digmp
12c3ezuA_



100.0 8 PDB header:signaling protein
Chain: A: PDB Molecule:ggdef domain protein;
PDBTitle: crystal structure of multidomain protein of unknown function with2 ggdef-domain (np_951600.1) from geobacter sulfurreducens at 1.95 a3 resolution
13c3breA_



99.9 9 PDB header:signaling protein
Chain: A: PDB Molecule:probable two-component response regulator;
PDBTitle: crystal structure of p.aeruginosa pa3702
14c3i5aA_



99.9 9 PDB header:signaling protein
Chain: A: PDB Molecule:response regulator/ggdef domain protein;
PDBTitle: crystal structure of full-length wpsr from pseudomonas syringae
15c3iclA_



99.9 12 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:eal/ggdef domain protein;
PDBTitle: x-ray structure of protein (eal/ggdef domain protein) from2 m.capsulatus, northeast structural genomics consortium3 target mcr174c
16c3i5bA_



99.9 10 PDB header:signaling protein
Chain: A: PDB Molecule:wspr response regulator;
PDBTitle: crystal structure of the isolated ggdef domain of wpsr from2 pseudomonas aeruginosa
17c3qyyB_



99.9 8 PDB header:signaling protein/inhibitor
Chain: B: PDB Molecule:response regulator;
PDBTitle: a novel interaction mode between a microbial ggdef domain and the bis-2 (3, 5 )-cyclic di-gmp
18c3i5cA_



99.9 12 PDB header:signaling protein
Chain: A: PDB Molecule:fusion of general control protein gcn4 and wspr response
PDBTitle: crystal structure of a fusion protein containing the leucine zipper of2 gcn4 and the ggdef domain of wspr from pseudomonas aeruginosa
19c3mtkA_



99.9 12 PDB header:transferase
Chain: A: PDB Molecule:diguanylate cyclase/phosphodiesterase;
PDBTitle: x-ray structure of diguanylate cyclase/phosphodiesterase from2 caldicellulosiruptor saccharolyticus, northeast structural genomics3 consortium target clr27c
20d1w25a3



99.9 11 Fold:Ferredoxin-like
Superfamily:Nucleotide cyclase
Family:GGDEF domain
21c3ignA_



not modelled 99.9 10 PDB header:transferase
Chain: A: PDB Molecule:diguanylate cyclase;
PDBTitle: crystal structure of the ggdef domain from marinobacter2 aquaeolei diguanylate cyclase complexed with c-di-gmp -3 northeast structural genomics consortium target mqr89a
22c3hvaA_



not modelled 99.9 12 PDB header:transferase
Chain: A: PDB Molecule:protein fimx;
PDBTitle: crystal structure of fimx ggdef domain from pseudomonas2 aeruginosa
23c3hvwA_



not modelled 99.8 9 PDB header:lyase
Chain: A: PDB Molecule:diguanylate-cyclase (dgc);
PDBTitle: crystal structure of the ggdef domain of the pa2567 protein2 from pseudomonas aeruginosa, northeast structural genomics3 consortium target par365c
24c3c8cB_



99.6 10 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:methyl-accepting chemotaxis protein;
PDBTitle: crystal structure of mcp_n and cache domains of methyl-2 accepting chemotaxis protein from vibrio cholerae
25c3licA_



99.5 11 PDB header:signaling protein
Chain: A: PDB Molecule:sensor protein;
PDBTitle: crystal structure of the extracellular domain of the putative2 histidine kinase sohk1s-z6
26c3libA_



99.4 10 PDB header:signaling protein
Chain: A: PDB Molecule:hypothetical sensory transduction histidine kinase;
PDBTitle: crystal structure of the extracellular domain of the putative2 histidine kinase mmhk1s-z3
27c2p7jA_



not modelled 99.4 12 PDB header:transcription
Chain: A: PDB Molecule:putative sensory box/ggdef family protein;
PDBTitle: crystal structure of the domain of putative sensory box/ggdef family2 protein from vibrio parahaemolyticus
28c3liaA_



99.4 13 PDB header:signaling protein
Chain: A: PDB Molecule:hypothetical sensory transduction histidine kinase;
PDBTitle: crystal structure of the extracellular domain of the putative2 histidine kinase mmhk1s-z2
29c3lifA_



not modelled 99.2 7 PDB header:signaling protein
Chain: A: PDB Molecule:putative diguanylate cyclase (ggdef) with pas/pac domain;
PDBTitle: crystal structure of the extracellular domain of the putative2 histidine kinase rphk1s-z16
30c3fosA_



not modelled 99.2 11 PDB header:transferase
Chain: A: PDB Molecule:sensor protein;
PDBTitle: crystal structure of two-component sensor histidine kinase domain from2 bacillus subtilis subsp. subtilis str. 168
31c3e4pB_



not modelled 99.1 8 PDB header:transferase
Chain: B: PDB Molecule:c4-dicarboxylate transport sensor protein dctb;
PDBTitle: crystal structure of malonate occupied dctb
32c3by9A_



not modelled 98.9 11 PDB header:transferase
Chain: A: PDB Molecule:sensor protein;
PDBTitle: crystal structure of the v. cholerae histidine kinase dctb2 sensor domain
33d2p7ja2



not modelled 98.3 12 Fold:Profilin-like
Superfamily:Sensory domain-like
Family:YkuI C-terminal domain-like
34c3p7nB_



not modelled 98.2 10 PDB header:dna binding protein
Chain: B: PDB Molecule:sensor histidine kinase;
PDBTitle: crystal structure of light activated transcription factor el222 from2 erythrobacter litoralis
35c2qv6D_



not modelled 97.0 9 PDB header:hydrolase
Chain: D: PDB Molecule:gtp cyclohydrolase iii;
PDBTitle: gtp cyclohydrolase iii from m. jannaschii (mj0145)2 complexed with gtp and metal ions
36c3khtA_



not modelled 95.6 13 PDB header:signaling protein
Chain: A: PDB Molecule:response regulator;
PDBTitle: crystal structure of response regulator from hahella chejuensis
37d2basa2



not modelled 95.4 16 Fold:Profilin-like
Superfamily:Sensory domain-like
Family:YkuI C-terminal domain-like
38c3q58A_



not modelled 94.3 14 PDB header:isomerase
Chain: A: PDB Molecule:n-acetylmannosamine-6-phosphate 2-epimerase;
PDBTitle: structure of n-acetylmannosamine-6-phosphate epimerase from salmonella2 enterica
39c2p0oA_



not modelled 94.1 16 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:hypothetical protein duf871;
PDBTitle: crystal structure of a conserved protein from locus ef_2437 in2 enterococcus faecalis with an unknown function
40c1cjkA_



not modelled 94.0 10 PDB header:lyase/lyase/signaling protein
Chain: A: PDB Molecule:adenylate cyclase, type v;
PDBTitle: complex of gs-alpha with the catalytic domains of mammalian adenylyl2 cyclase: complex with adenosine 5'-(alpha thio)-triphosphate (rp),3 mg, and mn
41d1a53a_



not modelled 93.4 18 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
42d1p6qa_



not modelled 93.2 13 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
43c3hebB_



not modelled 93.2 19 PDB header:transcription regulator
Chain: B: PDB Molecule:response regulator receiver domain protein (chey);
PDBTitle: crystal structure of response regulator receiver domain from2 rhodospirillum rubrum
44c2c3zA_



not modelled 93.2 18 PDB header:lyase
Chain: A: PDB Molecule:indole-3-glycerol phosphate synthase;
PDBTitle: crystal structure of a truncated variant of indole-3-2 glycerol phosphate synthase from sulfolobus solfataricus
45c2zayA_



not modelled 93.2 18 PDB header:signaling protein
Chain: A: PDB Molecule:response regulator receiver protein;
PDBTitle: crystal structure of response regulator from desulfuromonas2 acetoxidans
46c1ybuA_



not modelled 92.6 9 PDB header:hydrolase
Chain: A: PDB Molecule:lipj;
PDBTitle: mycobacterium tuberculosis adenylyl cyclase rv1900c chd, in complex2 with a substrate analog.
47d1mvoa_



not modelled 92.1 16 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
48d1azsa_



not modelled 91.5 9 Fold:Ferredoxin-like
Superfamily:Nucleotide cyclase
Family:Adenylyl and guanylyl cyclase catalytic domain
49d2asxa1



91.5 19 Fold:HAMP domain-like
Superfamily:HAMP domain-like
Family:HAMP domain
50c3b2nA_



not modelled 91.4 15 PDB header:transcription
Chain: A: PDB Molecule:uncharacterized protein q99uf4;
PDBTitle: crystal structure of dna-binding response regulator, luxr family, from2 staphylococcus aureus
51d1ua7a2



not modelled 91.3 12 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:Amylase, catalytic domain
52d1h3ga3



not modelled 90.7 14 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:Amylase, catalytic domain
53c2w01C_



not modelled 90.3 16 PDB header:lyase
Chain: C: PDB Molecule:adenylate cyclase;
PDBTitle: crystal structure of the guanylyl cyclase cya2
54c3lnrA_



90.3 13 PDB header:signaling protein
Chain: A: PDB Molecule:aerotaxis transducer aer2;
PDBTitle: crystal structure of poly-hamp domains from the p. aeruginosa soluble2 receptor aer2
55c3edeB_



not modelled 89.9 13 PDB header:hydrolase
Chain: B: PDB Molecule:cyclomaltodextrinase;
PDBTitle: structural base for cyclodextrin hydrolysis
56d1wc1a_



not modelled 89.7 6 Fold:Ferredoxin-like
Superfamily:Nucleotide cyclase
Family:Adenylyl and guanylyl cyclase catalytic domain
57c1qhoA_



not modelled 89.5 23 PDB header:hydrolase
Chain: A: PDB Molecule:alpha-amylase;
PDBTitle: five-domain alpha-amylase from bacillus stearothermophilus,2 maltose/acarbose complex
58d1yioa2



not modelled 89.4 14 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
59c3hv2B_



not modelled 89.3 8 PDB header:signaling protein
Chain: B: PDB Molecule:response regulator/hd domain protein;
PDBTitle: crystal structure of signal receiver domain of hd domain-2 containing protein from pseudomonas fluorescens pf-5
60d1gjwa2



not modelled 89.2 11 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:Amylase, catalytic domain
61c2jk1A_



not modelled 89.1 10 PDB header:dna-binding
Chain: A: PDB Molecule:hydrogenase transcriptional regulatory protein hupr1;
PDBTitle: crystal structure of the wild-type hupr receiver domain
62d2guya2



not modelled 89.0 8 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:Amylase, catalytic domain
63c3lrmB_



not modelled 89.0 13 PDB header:hydrolase
Chain: B: PDB Molecule:alpha-galactosidase 1;
PDBTitle: structure of alfa-galactosidase from saccharomyces cerevisiae with2 raffinose
64c1wc6B_



not modelled 88.8 10 PDB header:lyase
Chain: B: PDB Molecule:adenylate cyclase;
PDBTitle: soluble adenylyl cyclase cyac from s. platensis in complex2 with rp-atpalphas in presence of bicarbonate
65c3c97A_



not modelled 88.7 17 PDB header:signaling protein, transferase
Chain: A: PDB Molecule:signal transduction histidine kinase;
PDBTitle: crystal structure of the response regulator receiver domain2 of a signal transduction histidine kinase from aspergillus3 oryzae
66c2pz0B_



not modelled 88.7 13 PDB header:hydrolase
Chain: B: PDB Molecule:glycerophosphoryl diester phosphodiesterase;
PDBTitle: crystal structure of glycerophosphodiester phosphodiesterase (gdpd)2 from t. tengcongensis
67c3i42A_



not modelled 88.6 12 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:response regulator receiver domain protein (chey-
PDBTitle: structure of response regulator receiver domain (chey-like)2 from methylobacillus flagellatus
68d1bf2a3



not modelled 88.4 13 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:Amylase, catalytic domain
69d1w25a1



not modelled 88.4 16 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
70c1y10C_



not modelled 88.2 10 PDB header:lyase
Chain: C: PDB Molecule:hypothetical protein rv1264/mt1302;
PDBTitle: mycobacterial adenylyl cyclase rv1264, holoenzyme, inhibited state
71d1heya_



not modelled 88.1 14 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
72d1qhoa4



not modelled 87.6 23 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:Amylase, catalytic domain
73c2h6rG_



not modelled 87.4 8 PDB header:isomerase
Chain: G: PDB Molecule:triosephosphate isomerase;
PDBTitle: crystal structure of triosephosphate isomerase (tim) from2 methanocaldococcus jannaschii
74c1cygA_



not modelled 87.0 21 PDB header:glycosyltransferase
Chain: A: PDB Molecule:cyclodextrin glucanotransferase;
PDBTitle: cyclodextrin glucanotransferase (e.c.2.4.1.19) (cgtase)
75c3t8yA_



not modelled 86.9 17 PDB header:hydrolase
Chain: A: PDB Molecule:chemotaxis response regulator protein-glutamate
PDBTitle: crystal structure of the response regulator domain of thermotoga2 maritima cheb
76d1k68a_



not modelled 86.9 15 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
77c2rjnA_



not modelled 86.8 11 PDB header:hydrolase
Chain: A: PDB Molecule:response regulator receiver:metal-dependent
PDBTitle: crystal structure of an uncharacterized protein q2bku2 from2 neptuniibacter caesariensis
78d1krwa_



not modelled 86.5 16 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
79d1ps9a1



not modelled 86.3 12 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
80d1nvma2



not modelled 86.2 11 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:HMGL-like
81c3kruC_



not modelled 85.9 25 PDB header:oxidoreductase
Chain: C: PDB Molecule:nadh:flavin oxidoreductase/nadh oxidase;
PDBTitle: crystal structure of the thermostable old yellow enzyme from2 thermoanaerobacter pseudethanolicus e39
82c2iswB_



not modelled 85.8 19 PDB header:lyase
Chain: B: PDB Molecule:putative fructose-1,6-bisphosphate aldolase;
PDBTitle: structure of giardia fructose-1,6-biphosphate aldolase in2 complex with phosphoglycolohydroxamate
83d1lwha2



not modelled 85.6 9 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:Amylase, catalytic domain
84c1bagA_



not modelled 85.6 15 PDB header:alpha-amylase
Chain: A: PDB Molecule:alpha-1,4-glucan-4-glucanohydrolase;
PDBTitle: alpha-amylase from bacillus subtilis complexed with2 maltopentaose
85c2wcsA_



not modelled 85.4 17 PDB header:hydrolase
Chain: A: PDB Molecule:alpha amylase, catalytic region;
PDBTitle: crystal structure of debranching enzyme from nostoc2 punctiforme (npde)
86d2bhua3



not modelled 85.1 14 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:Amylase, catalytic domain
87c3igsB_



not modelled 85.0 13 PDB header:isomerase
Chain: B: PDB Molecule:n-acetylmannosamine-6-phosphate 2-epimerase 2;
PDBTitle: structure of the salmonella enterica n-acetylmannosamine-6-phosphate2 2-epimerase
88d1jbea_



not modelled 84.9 10 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
89d1u0sy_



not modelled 84.9 14 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
90d1k66a_



not modelled 84.8 22 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
91c3hf3A_



not modelled 84.6 20 PDB header:oxidoreductase
Chain: A: PDB Molecule:chromate reductase;
PDBTitle: old yellow enzyme from thermus scotoductus sa-01
92d1o1za_



not modelled 84.4 16 Fold:TIM beta/alpha-barrel
Superfamily:PLC-like phosphodiesterases
Family:Glycerophosphoryl diester phosphodiesterase
93d1ys7a2



not modelled 84.3 21 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
94c3qvqB_



not modelled 84.2 12 PDB header:hydrolase
Chain: B: PDB Molecule:phosphodiesterase olei02445;
PDBTitle: the structure of an oleispira antarctica phosphodiesterase olei024452 in complex with the product sn-glycerol-3-phosphate
95c3a23A_



not modelled 84.1 20 PDB header:hydrolase
Chain: A: PDB Molecule:putative secreted alpha-galactosidase;
PDBTitle: crystal structure of beta-l-arabinopyranosidase complexed with d-2 galactose
96c3cg0A_



not modelled 84.1 19 PDB header:lyase
Chain: A: PDB Molecule:response regulator receiver modulated diguanylate cyclase
PDBTitle: crystal structure of signal receiver domain of modulated diguanylate2 cyclase from desulfovibrio desulfuricans g20, an example of alternate3 folding
97c1tcmB_



not modelled 84.0 18 PDB header:glycosyltransferase
Chain: B: PDB Molecule:cyclodextrin glycosyltransferase;
PDBTitle: cyclodextrin glycosyltransferase w616a mutant from bacillus2 circulans strain 251
98d1dz3a_



not modelled 84.0 19 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
99c3nhzA_



not modelled 83.9 18 PDB header:dna binding protein
Chain: A: PDB Molecule:two component system transcriptional regulator mtra;
PDBTitle: structure of n-terminal domain of mtra
100c1gjuA_



not modelled 83.8 13 PDB header:transferase
Chain: A: PDB Molecule:maltodextrin glycosyltransferase;
PDBTitle: maltosyltransferase from thermotoga maritima
101d1eh9a3



not modelled 83.7 17 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:Amylase, catalytic domain
102c3gt7A_



not modelled 83.5 15 PDB header:hydrolase
Chain: A: PDB Molecule:sensor protein;
PDBTitle: crystal structure of signal receiver domain of signal2 transduction histidine kinase from syntrophus3 aciditrophicus
103d1qkka_



not modelled 83.3 15 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
104c1jibA_



not modelled 83.1 22 PDB header:hydrolase
Chain: A: PDB Molecule:neopullulanase;
PDBTitle: complex of alpha-amylase ii (tva ii) from thermoactinomyces2 vulgaris r-47 with maltotetraose based on a crystal soaked3 with maltohexaose.
105c2dh3A_



not modelled 83.0 21 PDB header:transport protein, signaling protein
Chain: A: PDB Molecule:4f2 cell-surface antigen heavy chain;
PDBTitle: crystal structure of human ed-4f2hc
106c1gviA_



not modelled 83.0 17 PDB header:hydrolase
Chain: A: PDB Molecule:maltogenic amylase;
PDBTitle: thermus maltogenic amylase in complex with beta-cd
107c1gcyA_



not modelled 82.9 11 PDB header:hydrolase
Chain: A: PDB Molecule:glucan 1,4-alpha-maltotetrahydrolase;
PDBTitle: high resolution crystal structure of maltotetraose-forming2 exo-amylase
108d1uoka2



not modelled 82.9 13 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:Amylase, catalytic domain
109d1zesa1



not modelled 82.5 17 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
110d1dbwa_



not modelled 82.4 15 Fold:Flavodoxin-like
Superfamily:CheY-like
Family:CheY-related
111c1zjaB_



not modelled 82.4 9 PDB header:isomerase
Chain: B: PDB Molecule:trehalulose synthase;
PDBTitle: crystal structure of the trehalulose synthase mutb from2 pseudomonas mesoacidophila mx-45 (triclinic form)
112d1piia2



not modelled 82.3 25 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
113d1y0ea_



not modelled 82.3 13 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:NanE-like
114d1pama4



not modelled 82.0 19 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:Amylase, catalytic domain
115c3rqiA_



not modelled 81.9 15 PDB header:transcription
Chain: A: PDB Molecule:response regulator protein;
PDBTitle: crystal structure of a response regulator protein from burkholderia2 pseudomallei with a phosphorylated aspartic acid, calcium ion and3 citrate
116c3gr7A_



not modelled 81.8 26 PDB header:oxidoreductase
Chain: A: PDB Molecule:nadph dehydrogenase;
PDBTitle: structure of oye from geobacillus kaustophilus, hexagonal2 crystal form
117c2zwmA_



not modelled 81.6 18 PDB header:transcription
Chain: A: PDB Molecule:transcriptional regulatory protein yycf;
PDBTitle: crystal structure of yycf receiver domain from bacillus2 subtilis
118c3a47A_



not modelled 81.4 15 PDB header:hydrolase
Chain: A: PDB Molecule:oligo-1,6-glucosidase;
PDBTitle: crystal structure of isomaltase from saccharomyces cerevisiae
119c1m53A_



not modelled 81.4 6 PDB header:isomerase
Chain: A: PDB Molecule:isomaltulose synthase;
PDBTitle: crystal structure of isomaltulose synthase (pali) from2 klebsiella sp. lx3
120d1cgta4



not modelled 81.3 16 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:Amylase, catalytic domain

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0