Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP05480
DateTue Jul 30 13:01:21 BST 2013
Unique Job IDf1d9cbe7c578d7c3
SequenceMGSNKSKPKD ... Download FASTA

Summary 

Top model
Image coloured by rainbow N → C terminus
Model dimensions (Å):X:89.686 Y:74.661 Z:71.237
Model (left) based on template c1y57A_
Top template information
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor
Confidence and coverage
Confidence:100.0% Coverage: 83%
451 residues ( 83% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
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Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MGSNKSKPKDASQRRRSLEPSENVHGAGGAFPASQTPSKPASADGHRGPSAAFVPPAAEP
Secondary structure 



























































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Disorder  ????????????????????????????????????????????????????????????
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   .........70.........80.........90.........100.........110.........120
Sequence  KLFGGFNSSDTVTSPQRAGPLAGGVTTFVALYDYESRTETDLSFKKGERLQIVNNTRKVD
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Disorder  ????????????????????????












??????












????
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   .........130.........140.........150.........160.........170.........180
Sequence  VREGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTF
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Disorder  ?






















??????




















?







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   .........190.........200.........210.........220.........230.........240
Sequence  LVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSK
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Disorder 



















???













?






???










?
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   .........250.........260.........270.........280.........290.........300
Sequence  HADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRV
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Disorder  ??????
?


?

?



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   .........310.........320.........330.........340.........350.........360
Sequence  AIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMNKGSLLDFLKG
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Disorder 





?

??
















































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   .........370.........380.........390.........400.........410.........420
Sequence  ETGKYLRLPQLVDMSAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIE
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Disorder 
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   .........430.........440.........450.........460.........470.........480
Sequence  DNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVL
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Disorder 
?


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   .........490.........500.........510.........520.........530.........540
Sequence  DQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGEN
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Disorder 



?????


?















?


?















??????????
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   .
Sequence  L
Secondary structure 
SS confidence 
Disorder  ?
Disorder confidence 
 

Confidence Key
High(9)                    Low (0)
?Disordered ( 28%)
Alpha helix ( 22%)
Beta strand ( 22%)

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1y57 chain A

3D model

Region: 85 - 541
Aligned: 451
Modelled: 457
Confidence: 100.0%
Identity: 99%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor

Phyre2

PDB 2h8h chain A

3D model

Region: 87 - 534
Aligned: 442
Modelled: 448
Confidence: 100.0%
Identity: 99%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: src kinase in complex with a quinazoline inhibitor

Phyre2

PDB 2fo0 chain A

3D model

Region: 78 - 532
Aligned: 441
Modelled: 455
Confidence: 100.0%
Identity: 43%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase abl1 (1b isoform);
PDBTitle: organization of the sh3-sh2 unit in active and inactive forms of the2 c-abl tyrosine kinase

Phyre2

PDB 1opl chain A

3D model

Region: 85 - 532
Aligned: 434
Modelled: 448
Confidence: 100.0%
Identity: 43%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase;
PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase

Phyre2

PDB 2c0i chain A

3D model

Region: 87 - 538
Aligned: 431
Modelled: 439
Confidence: 100.0%
Identity: 62%
PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase hck;
PDBTitle: src family kinase hck with bound inhibitor a-420983

Phyre2

PDB 1k9a chain B

3D model

Region: 81 - 530
Aligned: 424
Modelled: 450
Confidence: 100.0%
Identity: 42%
PDB header:transferase
Chain: B: PDB Molecule:carboxyl-terminal src kinase;
PDBTitle: crystal structure analysis of full-length carboxyl-terminal2 src kinase at 2.5 a resolution

Phyre2

PDB 4fl2 chain A

3D model

Region: 152 - 531
Aligned: 372
Modelled: 380
Confidence: 100.0%
Identity: 36%
PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase syk;
PDBTitle: structural and biophysical characterization of the syk activation2 switch

Phyre2

PDB 2ozo chain A

3D model

Region: 152 - 541
Aligned: 371
Modelled: 390
Confidence: 100.0%
Identity: 35%
PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase zap-70;
PDBTitle: autoinhibited intact human zap-70

Phyre2

PDB 3cbl chain A

3D model

Region: 146 - 527
Aligned: 343
Modelled: 381
Confidence: 100.0%
Identity: 40%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fes/fps;
PDBTitle: crystal structure of human feline sarcoma viral oncogene homologue (v-2 fes) in complex with staurosporine and a consensus peptide

Phyre2

PDB 2j0k chain B

3D model

Region: 266 - 534
Aligned: 254
Modelled: 269
Confidence: 100.0%
Identity: 40%
PDB header:transferase
Chain: B: PDB Molecule:focal adhesion kinase 1;
PDBTitle: crystal structure of a fragment of focal adhesion kinase2 containing the ferm and kinase domains.

Phyre2

PDB 1qcf chain A domain 3

3D model

Region: 258 - 538
Aligned: 281
Modelled: 281
Confidence: 100.0%
Identity: 67%
Fold: Protein kinase-like (PK-like)
Superfamily: Protein kinase-like (PK-like)
Family: Protein kinases, catalytic subunit

Phyre2

PDB 1qpc chain A

3D model

Region: 261 - 531
Aligned: 270
Modelled: 271
Confidence: 100.0%
Identity: 64%
Fold: Protein kinase-like (PK-like)
Superfamily: Protein kinase-like (PK-like)
Family: Protein kinases, catalytic subunit

Phyre2

PDB 1opj chain A

3D model

Region: 259 - 528
Aligned: 270
Modelled: 270
Confidence: 100.0%
Identity: 48%
Fold: Protein kinase-like (PK-like)
Superfamily: Protein kinase-like (PK-like)
Family: Protein kinases, catalytic subunit

Phyre2

PDB 4im2 chain A

3D model

Region: 270 - 529
Aligned: 239
Modelled: 242
Confidence: 100.0%
Identity: 26%
PDB header:transferase/transferase inhibitor
Chain: A: PDB Molecule:serine/threonine-protein kinase tbk1;
PDBTitle: structure of tank-binding kinase 1

Phyre2

PDB 1fmk chain A domain 3

3D model

Region: 257 - 541
Aligned: 270
Modelled: 285
Confidence: 100.0%
Identity: 99%
Fold: Protein kinase-like (PK-like)
Superfamily: Protein kinase-like (PK-like)
Family: Protein kinases, catalytic subunit

Phyre2

PDB 3pfq chain A

3D model

Region: 268 - 521
Aligned: 248
Modelled: 254
Confidence: 100.0%
Identity: 25%
PDB header:transferase
Chain: A: PDB Molecule:protein kinase c beta type;
PDBTitle: crystal structure and allosteric activation of protein kinase c beta2 ii

Phyre2

PDB 1u59 chain A

3D model

Region: 267 - 540
Aligned: 273
Modelled: 274
Confidence: 100.0%
Identity: 34%
Fold: Protein kinase-like (PK-like)
Superfamily: Protein kinase-like (PK-like)
Family: Protein kinases, catalytic subunit

Phyre2

PDB 3nyo chain B

3D model

Region: 266 - 522
Aligned: 254
Modelled: 257
Confidence: 100.0%
Identity: 26%
PDB header:transferase
Chain: B: PDB Molecule:g protein-coupled receptor kinase 6;
PDBTitle: crystal structure of g protein-coupled receptor kinase 6 in complex2 with amp

Phyre2

PDB 3qa8 chain H

3D model

Region: 276 - 516
Aligned: 238
Modelled: 241
Confidence: 100.0%
Identity: 25%
PDB header:immune system, signaling protein
Chain: H: PDB Molecule:mgc80376 protein;
PDBTitle: crystal structure of inhibitor of kappa b kinase beta

Phyre2

PDB 3zzw chain A

3D model

Region: 269 - 527
Aligned: 257
Modelled: 259
Confidence: 100.0%
Identity: 37%
PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase transmembrane receptor ror2;
PDBTitle: crystal structure of the kinase domain of ror2

Phyre2
1

c1y57A_
2

c2h8hA_
3

c2fo0A_
4

c1oplA_
5

c2c0iA_
6

c1k9aB_
7

c4fl2A_
8

c2ozoA_
9

c3cblA_
10

c2j0kB_
11

d1qcfa3
12

d1qpca_
13

d1opja_
14

c4im2A_
15

d1fmka3
16

c3pfqA_
17

d1u59a_
18

c3nyoB_
19

c3qa8H_
20

c3zzwA_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c1y57A_



100.0 99 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor
2c2h8hA_



100.0 99 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: src kinase in complex with a quinazoline inhibitor
3c2fo0A_



100.0 43 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase abl1 (1b isoform);
PDBTitle: organization of the sh3-sh2 unit in active and inactive forms of the2 c-abl tyrosine kinase
4c1oplA_



100.0 43 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase;
PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase
5c2c0iA_



100.0 62 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase hck;
PDBTitle: src family kinase hck with bound inhibitor a-420983
6c1k9aB_



100.0 42 PDB header:transferase
Chain: B: PDB Molecule:carboxyl-terminal src kinase;
PDBTitle: crystal structure analysis of full-length carboxyl-terminal2 src kinase at 2.5 a resolution
7c4fl2A_



100.0 36 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase syk;
PDBTitle: structural and biophysical characterization of the syk activation2 switch
8c2ozoA_



100.0 35 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase zap-70;
PDBTitle: autoinhibited intact human zap-70
9c3cblA_



100.0 40 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fes/fps;
PDBTitle: crystal structure of human feline sarcoma viral oncogene homologue (v-2 fes) in complex with staurosporine and a consensus peptide
10c2j0kB_



100.0 40 PDB header:transferase
Chain: B: PDB Molecule:focal adhesion kinase 1;
PDBTitle: crystal structure of a fragment of focal adhesion kinase2 containing the ferm and kinase domains.
11d1qcfa3



100.0 67 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
12d1qpca_



100.0 64 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
13d1opja_



100.0 48 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
14c4im2A_



100.0 26 PDB header:transferase/transferase inhibitor
Chain: A: PDB Molecule:serine/threonine-protein kinase tbk1;
PDBTitle: structure of tank-binding kinase 1
15d1fmka3



100.0 99 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
16c3pfqA_



100.0 25 PDB header:transferase
Chain: A: PDB Molecule:protein kinase c beta type;
PDBTitle: crystal structure and allosteric activation of protein kinase c beta2 ii
17d1u59a_



100.0 34 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
18c3nyoB_



100.0 26 PDB header:transferase
Chain: B: PDB Molecule:g protein-coupled receptor kinase 6;
PDBTitle: crystal structure of g protein-coupled receptor kinase 6 in complex2 with amp
19c3qa8H_



100.0 25 PDB header:immune system, signaling protein
Chain: H: PDB Molecule:mgc80376 protein;
PDBTitle: crystal structure of inhibitor of kappa b kinase beta
20c3zzwA_



100.0 37 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase transmembrane receptor ror2;
PDBTitle: crystal structure of the kinase domain of ror2
21c2acxB_



not modelled 100.0 26 PDB header:transferase
Chain: B: PDB Molecule:g protein-coupled receptor kinase 6;
PDBTitle: crystal structure of g protein coupled receptor kinase 6 bound to2 amppnp
22d1k2pa_



not modelled 100.0 42 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
23c2ivsA_



not modelled 100.0 40 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase receptor
PDBTitle: crystal structure of non-phosphorylated ret tyrosine kinase2 domain
24c3g0eA_



not modelled 100.0 39 PDB header:transferase
Chain: A: PDB Molecule:mast/stem cell growth factor receptor;
PDBTitle: kit kinase domain in complex with sunitinib
25c3c4wB_



not modelled 100.0 23 PDB header:transferase
Chain: B: PDB Molecule:rhodopsin kinase;
PDBTitle: crystal structure of g protein coupled receptor kinase 1 bound to atp2 and magnesium chloride at 2.7a
26c3ckxA_



not modelled 100.0 30 PDB header:transferase
Chain: A: PDB Molecule:serine/threonine-protein kinase 24;
PDBTitle: crystal structure of sterile 20-like kinase 3 (mst3, stk24)2 in complex with staurosporine
27c1ym7C_



not modelled 100.0 20 PDB header:transferase
Chain: C: PDB Molecule:beta-adrenergic receptor kinase 1;
PDBTitle: g protein-coupled receptor kinase 2 (grk2)
28d1lufa_



not modelled 100.0 37 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
29c1lufA_



not modelled 100.0 37 PDB header:transferase
Chain: A: PDB Molecule:muscle-specific tyrosine kinase receptor musk;
PDBTitle: crystal structure of the musk tyrosine kinase: insights2 into receptor autoregulation
30c3qa8A_



not modelled 100.0 25 PDB header:immune system, signaling protein
Chain: A: PDB Molecule:mgc80376 protein;
PDBTitle: crystal structure of inhibitor of kappa b kinase beta
31c3c4yA_



not modelled 100.0 23 PDB header:transferase
Chain: A: PDB Molecule:rhodopsin kinase;
PDBTitle: crystal structure of apo form of g protein coupled receptor kinase 12 at 7.51a
32c2pvfA_



not modelled 100.0 38 PDB header:transferase
Chain: A: PDB Molecule:fibroblast growth factor receptor 2;
PDBTitle: crystal structure of tyrosine phosphorylated activated fgf receptor 22 (fgfr2) kinase domain in complex with atp analog and substrate3 peptide
33c3dpkA_



not modelled 100.0 39 PDB header:transferase
Chain: A: PDB Molecule:macrophage colony-stimulating factor 1 receptor;
PDBTitle: cfms tyrosine kinase in complex with a pyridopyrimidinone2 inhibitor
34c2vwiC_



not modelled 100.0 29 PDB header:transferase
Chain: C: PDB Molecule:serine/threonine-protein kinase osr1;
PDBTitle: structure of the osr1 kinase, a hypertension drug target
35d2psqa1



not modelled 100.0 39 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
36c2psqA_



not modelled 100.0 39 PDB header:transferase
Chain: A: PDB Molecule:fibroblast growth factor receptor 2;
PDBTitle: crystal structure of unphosphorylated unactivated wild type2 fgf receptor 2 (fgfr2) kinase domain
37c1koaA_



not modelled 100.0 25 PDB header:kinase
Chain: A: PDB Molecule:twitchin;
PDBTitle: twitchin kinase fragment (c.elegans), autoregulated protein2 kinase and immunoglobulin domains
38d3bu3a1



not modelled 100.0 40 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
39c3tkuB_



not modelled 100.0 23 PDB header:transferase/transferase inhibitor
Chain: B: PDB Molecule:serine/threonine-protein kinase mrck beta;
PDBTitle: mrck beta in complex with fasudil
40d2j4za1



not modelled 100.0 23 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
41c2c30A_



not modelled 100.0 23 PDB header:transferase
Chain: A: PDB Molecule:serine/threonine-protein kinase pak 6;
PDBTitle: crystal structure of the human p21-activated kinase 6
42c4ebwA_



not modelled 100.0 40 PDB header:transferase/transferase inhibitor
Chain: A: PDB Molecule:focal adhesion kinase 1;
PDBTitle: structure of focal adhesion kinase catalytic domain in complex with2 novel allosteric inhibitor
43c3kulB_



not modelled 100.0 44 PDB header:transferase
Chain: B: PDB Molecule:ephrin type-a receptor 8;
PDBTitle: kinase domain of human ephrin type-a receptor 8 (epha8)
44c3q5iA_



not modelled 100.0 25 PDB header:transferase
Chain: A: PDB Molecule:protein kinase;
PDBTitle: crystal structure of pbanka_031420
45c3plsA_



not modelled 100.0 38 PDB header:transferase
Chain: A: PDB Molecule:macrophage-stimulating protein receptor;
PDBTitle: ron in complex with ligand amp-pnp
46c4dn5A_



not modelled 100.0 21 PDB header:transferase
Chain: A: PDB Molecule:mitogen-activated protein kinase kinase kinase 14;
PDBTitle: crystal structure of nf-kb-inducing kinase (nik)
47c4aojA_



not modelled 100.0 37 PDB header:transferase
Chain: A: PDB Molecule:high affinity nerve growth factor receptor;
PDBTitle: human trka in complex with the inhibitor az-23
48c3soaA_



not modelled 100.0 23 PDB header:transferase/transferase inhibitor
Chain: A: PDB Molecule:calcium/calmodulin-dependent protein kinase type ii subunit
PDBTitle: full-length human camkii
49c4fijA_



not modelled 100.0 22 PDB header:transferase
Chain: A: PDB Molecule:serine/threonine-protein kinase pak 4;
PDBTitle: catalytic domain of human pak4
50d1sm2a_



not modelled 100.0 43 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
51c2wtkC_



not modelled 100.0 27 PDB header:transferase/metal-binding protein
Chain: C: PDB Molecule:serine/threonine-protein kinase 11;
PDBTitle: structure of the heterotrimeric lkb1-stradalpha-mo25alpha2 complex
52d1mp8a_



not modelled 100.0 40 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
53d1xbba_



not modelled 100.0 37 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
54d1t46a_



not modelled 100.0 38 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
55c3lxkA_



not modelled 100.0 37 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase jak3;
PDBTitle: structural and thermodynamic characterization of the tyk2 and jak32 kinase domains in complex with cp-690550 and cmp-6
56c2bujA_



not modelled 100.0 22 PDB header:transferase
Chain: A: PDB Molecule:serine/threonine-protein kinase 16;
PDBTitle: crystal structure of the human serine-threonine kinase 162 in complex with staurosporine
57c3eygA_



not modelled 100.0 35 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase;
PDBTitle: crystal structures of jak1 and jak2 inhibitor complexes
58c3lvpD_



not modelled 100.0 40 PDB header:transferase
Chain: D: PDB Molecule:insulin-like growth factor 1 receptor;
PDBTitle: crystal structure of bisphosphorylated igf1-r kinase domain (2p) in2 complex with a bis-azaindole inhibitor
59d1p4oa_



not modelled 100.0 37 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
60d1fgka_



not modelled 100.0 38 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
61d1uwha_



not modelled 100.0 33 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
62c4fieB_



not modelled 100.0 22 PDB header:transferase
Chain: B: PDB Molecule:serine/threonine-protein kinase pak 4;
PDBTitle: full-length human pak4
63d1yhwa1



not modelled 100.0 23 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
64c1yvjA_



not modelled 100.0 36 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase jak3;
PDBTitle: crystal structure of the jak3 kinase domain in complex with2 a staurosporine analogue
65c2a1aB_



not modelled 100.0 22 PDB header:protein synthesis/transferase
Chain: B: PDB Molecule:interferon-induced, double-stranded rna-activated protein
PDBTitle: pkr kinase domain-eif2alpha complex
66c3d4qA_



not modelled 100.0 36 PDB header:transferase
Chain: A: PDB Molecule:b-raf proto-oncogene serine/threonine-protein kinase;
PDBTitle: pyrazole-based inhibitors of b-raf kinase
67c3cc6A_



not modelled 100.0 39 PDB header:transferase
Chain: A: PDB Molecule:protein tyrosine kinase 2 beta;
PDBTitle: crystal structure of kinase domain of protein tyrosine kinase 2 beta2 (ptk2b)
68c2jamB_



not modelled 100.0 27 PDB header:transferase
Chain: B: PDB Molecule:calcium/calmodulin-dependent protein kinase type
PDBTitle: crystal structure of human calmodulin-dependent protein2 kinase i g
69c3sxrA_



not modelled 100.0 43 PDB header:transferase/transferase inhibitor
Chain: A: PDB Molecule:cytoplasmic tyrosine-protein kinase bmx;
PDBTitle: crystal structure of bmx non-receptor tyrosine kinase complex with2 dasatinib
70c3l9pA_



not modelled 100.0 38 PDB header:transferase
Chain: A: PDB Molecule:anaplastic lymphoma kinase;
PDBTitle: crystal structure of the anaplastic lymphoma kinase catalytic domain
71c4eutA_



not modelled 100.0 26 PDB header:transferase/transferase inhibitor
Chain: A: PDB Molecule:serine/threonine-protein kinase tbk1;
PDBTitle: structure of bx-795 complexed with unphosphorylated human tbk1 kinase-2 uld domain
72c3fbvL_



not modelled 100.0 25 PDB header:transferase, hydrolase
Chain: L: PDB Molecule:serine/threonine-protein kinase/endoribonuclease ire1;
PDBTitle: crystal structure of the oligomer formed by the kinase-ribonuclease2 domain of ire1
73c3lijA_



not modelled 100.0 27 PDB header:transferase
Chain: A: PDB Molecule:calcium/calmodulin dependent protein kinase with
PDBTitle: crystal structure of full length cpcdpk3 (cgd5_820) in2 complex with ca2+ and amppnp
74c2bmcD_



not modelled 100.0 24 PDB header:transferase
Chain: D: PDB Molecule:serine threonine-protein kinase 6;
PDBTitle: aurora-2 t287d t288d complexed with pha-680632
75c3fupB_



not modelled 100.0 31 PDB header:transferase
Chain: B: PDB Molecule:tyrosine-protein kinase jak2;
PDBTitle: crystal structures of jak1 and jak2 inhibitor complexes
76c3d9vA_



not modelled 100.0 22 PDB header:transferase
Chain: A: PDB Molecule:rho-associated protein kinase 1;
PDBTitle: crystal structure of rock i bound to h-1152p a di-2 methylated variant of fasudil
77d1jpaa_



not modelled 100.0 45 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
78d1phka_



not modelled 100.0 25 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
79c2w1iB_



not modelled 100.0 31 PDB header:transferase
Chain: B: PDB Molecule:jak2;
PDBTitle: structure determination of aurora kinase in complex with2 inhibitor
80d1mqba_



not modelled 100.0 46 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
81c3v5qB_



not modelled 100.0 36 PDB header:transferase/transferase inhibitor
Chain: B: PDB Molecule:nt-3 growth factor receptor;
PDBTitle: discovery of a selective trk inhibitor with efficacy in rodent cancer2 tumor models
82c3dfaA_



not modelled 100.0 28 PDB header:transferase
Chain: A: PDB Molecule:calcium-dependent protein kinase cgd3_920;
PDBTitle: crystal structure of kinase domain of calcium-dependent protein kinase2 cgd3_920 from cryptosporidium parvum
83c3vw6B_



not modelled 100.0 26 PDB header:transferase/transferase inhibitor
Chain: B: PDB Molecule:mitogen-activated protein kinase kinase kinase 5;
PDBTitle: crystal structure of human apoptosis signal-regulating kinase 1 (ask1)2 with imidazopyridine inhibitor
84c2qg5D_



not modelled 100.0 25 PDB header:transferase
Chain: D: PDB Molecule:calcium/calmodulin-dependent protein kinase;
PDBTitle: cryptosporidium parvum calcium dependent protein kinase cgd7_1840
85d1fvra_



not modelled 100.0 37 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
86d1rjba_



not modelled 100.0 42 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
87c2clqA_



not modelled 100.0 25 PDB header:transferase
Chain: A: PDB Molecule:mitogen-activated protein kinase kinase kinase 5;
PDBTitle: structure of mitogen-activated protein kinase kinase kinase2 5
88d1ckia_



not modelled 100.0 19 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
89c2j51A_



not modelled 100.0 24 PDB header:transferase
Chain: A: PDB Molecule:ste20-like serine/threonine-protein kinase;
PDBTitle: crystal structure of human ste20-like kinase bound to 5-2 amino-3-((4-(aminosulfonyl)phenyl)amino)-n-(2,6-3 difluorophenyl)-1h-1,2,4-triazole-1-carbothioamide
90d1xkka_



not modelled 100.0 33 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
91c1xkkA_



not modelled 100.0 33 PDB header:transferase
Chain: A: PDB Molecule:epidermal growth factor receptor;
PDBTitle: egfr kinase domain complexed with a quinazoline inhibitor-2 gw572016
92c3lxnA_



not modelled 100.0 35 PDB header:transferase
Chain: A: PDB Molecule:non-receptor tyrosine-protein kinase tyk2;
PDBTitle: structural and thermodynamic characterization of the tyk2 and jak32 kinase domains in complex with cp-690550 and cmp-6
93c1mruB_



not modelled 100.0 31 PDB header:transferase
Chain: B: PDB Molecule:probable serine/threonine-protein kinase pknb;
PDBTitle: intracellular ser/thr protein kinase domain of2 mycobacterium tuberculosis pknb.
94d2jfla1



not modelled 100.0 24 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
95c2y7jB_



not modelled 100.0 22 PDB header:transferase
Chain: B: PDB Molecule:phosphorylase b kinase gamma catalytic chain,
PDBTitle: structure of human phosphorylase kinase, gamma 2
96c2a27B_



not modelled 100.0 25 PDB header:transferase
Chain: B: PDB Molecule:death-associated protein kinase 2;
PDBTitle: human drp-1 kinase, w305s s308a d40 mutant, crystal form with 82 monomers in the asymmetric unit
97c3hztA_



not modelled 100.0 29 PDB header:transferase
Chain: A: PDB Molecule:calcium-dependent protein kinase 3;
PDBTitle: crystal structure of toxoplasma gondii cdpk3, tgme49_105860
98c2qobA_



not modelled 100.0 42 PDB header:transferase
Chain: A: PDB Molecule:ephrin receptor;
PDBTitle: human epha3 kinase domain, base structure
99c4hzsA_



not modelled 100.0 39 PDB header:transferase
Chain: A: PDB Molecule:activated cdc42 kinase 1;
PDBTitle: crystal structure of ack1 kinase domain with c-terminal sh3 domain
100c2zv2A_



not modelled 100.0 26 PDB header:transferase/transferase inhibitor
Chain: A: PDB Molecule:calcium/calmodulin-dependent protein kinase kinase 2;
PDBTitle: crystal structure of human calcium/calmodulin-dependent protein kinase2 kinase 2, beta, camkk2 kinase domain in complex with sto-609
101c2pziA_



not modelled 100.0 23 PDB header:transferase
Chain: A: PDB Molecule:probable serine/threonine-protein kinase pkng;
PDBTitle: crystal structure of protein kinase pkng from mycobacterium2 tuberculosis in complex with tetrahydrobenzothiophene ax20017
102d1jksa_



not modelled 100.0 25 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
103c3sv0A_



not modelled 100.0 21 PDB header:transferase
Chain: A: PDB Molecule:casein kinase i-like;
PDBTitle: crystal structure of casein kinase-1 like protein in plant
104c1xjdA_



not modelled 100.0 26 PDB header:transferase
Chain: A: PDB Molecule:protein kinase c, theta type;
PDBTitle: crystal structure of pkc-theta complexed with staurosporine2 at 2a resolution
105d1xjda_



not modelled 100.0 26 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
106c2vd5A_



not modelled 100.0 24 PDB header:transferase
Chain: A: PDB Molecule:dmpk protein;
PDBTitle: structure of human myotonic dystrophy protein kinase in2 complex with the bisindoylmaleide inhibitor bim viii
107c4e1zA_



not modelled 100.0 34 PDB header:transferase/transferase inhibitor
Chain: A: PDB Molecule:non-receptor tyrosine-protein kinase tyk2;
PDBTitle: structure of mouse tyk-2 complexed to a 3-aminoindazole inhibitor
108c2cgvA_



not modelled 100.0 26 PDB header:transferase
Chain: A: PDB Molecule:serine/threonine-protein kinase chk1;
PDBTitle: identification of chemically diverse chk1 inhibitors by2 receptor-based virtual screening
109d1byga_



not modelled 100.0 47 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
110c2chlA_



not modelled 100.0 22 PDB header:transferase
Chain: A: PDB Molecule:casein kinase i isoform gamma-3;
PDBTitle: structure of casein kinase 1 gamma 3
111c3p23B_



not modelled 100.0 22 PDB header:hydrolase, transferase
Chain: B: PDB Molecule:serine/threonine-protein kinase/endoribonuclease ire1;
PDBTitle: crystal structure of the human kinase and rnase domains in complex2 with adp
112c4eqmE_



not modelled 100.0 25 PDB header:transferase
Chain: E: PDB Molecule:protein kinase;
PDBTitle: structural analysis of staphylococcus aureus serine/threonine kinase2 pknb
113c2wtkB_



not modelled 100.0 22 PDB header:transferase/metal-binding protein
Chain: B: PDB Molecule:ste20-related kinase adapter protein alpha;
PDBTitle: structure of the heterotrimeric lkb1-stradalpha-mo25alpha2 complex
114c2bdwB_



not modelled 100.0 24 PDB header:transferase
Chain: B: PDB Molecule:hypothetical protein k11e8.1d;
PDBTitle: crystal structure of the auto-inhibited kinase domain of2 calcium/calmodulin activated kinase ii
115c2ya9A_



not modelled 100.0 24 PDB header:transferase
Chain: A: PDB Molecule:death-associated protein kinase 2;
PDBTitle: crystal structure of the autoinhibited form of mouse dapk2
116c2wqmA_



not modelled 100.0 24 PDB header:transferase
Chain: A: PDB Molecule:serine/threonine-protein kinase nek7;
PDBTitle: structure of apo human nek7
117d1o6ya_



not modelled 100.0 31 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
118c3comB_



not modelled 100.0 27 PDB header:transferase
Chain: B: PDB Molecule:serine/threonine-protein kinase 4;
PDBTitle: crystal structure of mst1 kinase
119c4ithB_



not modelled 100.0 30 PDB header:transferase/transferase inhibitor
Chain: B: PDB Molecule:receptor-interacting serine/threonine-protein kinase 1;
PDBTitle: crystal structure of rip1 kinase in complex with necrostatin-1 analog
120d1nvra_



not modelled 100.0 26 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit

Binding site prediction 

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If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite