PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c4ebwA_

Fold library id	PDB Header	Molecule	Title
c4ebwA_	PDB header: transferase/transferase inhibitor	Chain: A: PDB Molecule: focal adhesion kinase 1;	PDBTitle: structure of focal adhesion kinase catalytic domain in complex with2 novel allosteric inhibitor

Links to external resources
Added to library: Sat Jul 28 14:29:03 2012

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence S T R D Y E I Q R E R I E L G R C I G E G Q F G D V H Q G I Y M S N P A L A V A I K T C K N C T S D S V R E K F L Q E A L T M R Q F D H P H

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
G G G B
G G G B S S S
T T T T S T
T T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence I V K L I G V I T E N P V W I I M E L C T L G E L R S F L Q V R K Y S L D L A S L I L Y A Y Q L S T A L A Y L E S K R F V H R D I A A R N V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) B
S S S
T T
B T T T T
T T
G G G

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence L V S S N D C V K L G D F G L K L P I K W M A P E S I N F R R F T S A S D V W M F G V C M W E I L M H G V K P F Q G V K N N D V I G R I E N

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T S B
G G G S
T T T
S S T T
T T

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . .

Sequence G E R L P M P P N C P P T L Y S L M T K C W A Y D P S R R P R F T E L K A Q L S T I L E E E K A Q

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
T T
T
S S T T T S
T

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	S	T	R	D	Y	E	I	Q	R	E	R	I	E	L	G	R	C	I	G	E	G	Q	F	G	D	V	H	Q	G	I	Y	M	S	N	P	A	L	A	V	A	I	K	T	C	K	N	C	T	S	D	S	V	R	E	K	F	L	Q	E	A	L	T	M	R	Q	F	D	H	P	H
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			G	G	G	B			G	G	G										B	S	S	S																					T	T	T	T	S																T				T	T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	I	V	K	L	I	G	V	I	T	E	N	P	V	W	I	I	M	E	L	C	T	L	G	E	L	R	S	F	L	Q	V	R	K	Y	S	L	D	L	A	S	L	I	L	Y	A	Y	Q	L	S	T	A	L	A	Y	L	E	S	K	R	F	V	H	R	D	I	A	A	R	N	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	B									S	S	S									T	T		B								T	T	T	T																							T	T						G	G	G
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	L	V	S	S	N	D	C	V	K	L	G	D	F	G	L	K	L	P	I	K	W	M	A	P	E	S	I	N	F	R	R	F	T	S	A	S	D	V	W	M	F	G	V	C	M	W	E	I	L	M	H	G	V	K	P	F	Q	G	V	K	N	N	D	V	I	G	R	I	E	N
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)					T	T						S	B						G	G	G	S																												T	T	T			S	S	T	T			T									T
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.
Sequence	G	E	R	L	P	M	P	P	N	C	P	P	T	L	Y	S	L	M	T	K	C	W	A	Y	D	P	S	R	R	P	R	F	T	E	L	K	A	Q	L	S	T	I	L	E	E	E	K	A	Q
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T							T	T													T		S	S	T	T	T	S																			T