Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionQ13239
DateFri May 25 09:47:59 BST 2012
Unique Job ID88c2f27fb1b4ef82

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c1y57A_
Top template information
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor
Confidence and coverage
Confidence:100.0% Coverage: 60%
165 residues ( 60% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
272 residues ( 99%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MGNSMKSTPAPAERPLPNPEGLDSDFLAVLSDYPSPDISPPIFRRGEKLRVISDEGGWWK
Secondary structure 














































SS confidence 



























































Disorder  ????????????????????????












??

?

















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   .........70.........80.........90.........100.........110.........120
Sequence  AISLSTGRESYIPGICVARVYHGWLFEGLGRDKAEELLQLPDTKVGSFMIRESETKKGFY
Secondary structure 































SS confidence 



























































Disorder 



????



















































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   .........130.........140.........150.........160.........170.........180
Sequence  SLSVRHRQVKHYRIFRLPNNWYYISPRLTFQCLEDLVNHYSEVADGLCCVLTTPCLTQST
Secondary structure 
























SS confidence 



























































Disorder 























































????
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   .........190.........200.........210.........220.........230.........240
Sequence  AAPAVRASSSPVTLRQKTVDWRRVSRLQEDPEGTENPLGVDESLFSYGLRESIASYLSLT
Secondary structure 



































SS confidence 



























































Disorder  ?????????????
??????
?




??????????????????????







???
Disorder confidence 



























































 
   .........250.........260.........270......
Sequence  SEDNTSFDRKKKSISLMYGGSKRKSSFFSSPPYFED
Secondary structure 













SS confidence 



































Disorder  ??












???




?


?????????
Disorder confidence 



































 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1y57 chain A

3D model

Region: 25 - 189
Aligned: 165
Modelled: 165
Confidence: 100.0%
Identity: 41%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor

Phyre2

PDB 2c0i chain A

3D model

Region: 26 - 187
Aligned: 162
Modelled: 162
Confidence: 100.0%
Identity: 46%
PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase hck;
PDBTitle: src family kinase hck with bound inhibitor a-420983

Phyre2

PDB 2fo0 chain A

3D model

Region: 16 - 184
Aligned: 167
Modelled: 169
Confidence: 100.0%
Identity: 31%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase abl1 (1b isoform);
PDBTitle: organization of the sh3-sh2 unit in active and inactive forms of the2 c-abl tyrosine kinase

Phyre2

PDB 1x27 chain F

3D model

Region: 25 - 177
Aligned: 153
Modelled: 153
Confidence: 100.0%
Identity: 48%
PDB header:signaling protein
Chain: F: PDB Molecule:proto-oncogene tyrosine-protein kinase lck;
PDBTitle: crystal structure of lck sh2-sh3 with sh2 binding site of2 p130cas

Phyre2

PDB 3nhn chain A

3D model

Region: 24 - 176
Aligned: 153
Modelled: 153
Confidence: 100.0%
Identity: 48%
PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase hck;
PDBTitle: crystal structure of the src-family kinase hck sh3-sh2-linker2 regulatory region

Phyre2

PDB 2h8h chain A

3D model

Region: 27 - 184
Aligned: 158
Modelled: 158
Confidence: 100.0%
Identity: 42%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: src kinase in complex with a quinazoline inhibitor

Phyre2

PDB 2abl chain A

3D model

Region: 19 - 175
Aligned: 155
Modelled: 157
Confidence: 100.0%
Identity: 32%
PDB header:transferase
Chain: A: PDB Molecule:abl tyrosine kinase;
PDBTitle: sh3-sh2 domain fragment of human bcr-abl tyrosine kinase

Phyre2

PDB 1opl chain A

3D model

Region: 23 - 191
Aligned: 167
Modelled: 167
Confidence: 100.0%
Identity: 29%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase;
PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase

Phyre2

PDB 1k9a chain B

3D model

Region: 20 - 184
Aligned: 162
Modelled: 165
Confidence: 100.0%
Identity: 29%
PDB header:transferase
Chain: B: PDB Molecule:carboxyl-terminal src kinase;
PDBTitle: crystal structure analysis of full-length carboxyl-terminal2 src kinase at 2.5 a resolution

Phyre2

PDB 1g83 chain A

3D model

Region: 26 - 174
Aligned: 149
Modelled: 149
Confidence: 100.0%
Identity: 46%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fyn;
PDBTitle: crystal structure of fyn sh3-sh2

Phyre2

PDB 2oq1 chain A

3D model

Region: 82 - 274
Aligned: 193
Modelled: 193
Confidence: 100.0%
Identity: 23%
PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase zap-70;
PDBTitle: tandem sh2 domains of zap-70 with 19-mer zeta1 peptide

Phyre2

PDB 2ozo chain A

3D model

Region: 83 - 274
Aligned: 192
Modelled: 192
Confidence: 100.0%
Identity: 24%
PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase zap-70;
PDBTitle: autoinhibited intact human zap-70

Phyre2

PDB 2shp chain A

3D model

Region: 80 - 275
Aligned: 183
Modelled: 196
Confidence: 100.0%
Identity: 22%
PDB header:tyrosine phosphatase
Chain: A: PDB Molecule:shp-2;
PDBTitle: tyrosine phosphatase shp-2

Phyre2

PDB 3ps5 chain A

3D model

Region: 83 - 275
Aligned: 181
Modelled: 193
Confidence: 100.0%
Identity: 23%
PDB header:hydrolase, signaling protein
Chain: A: PDB Molecule:tyrosine-protein phosphatase non-receptor type 6;
PDBTitle: crystal structure of the full-length human protein tyrosine2 phosphatase shp-1

Phyre2

PDB 2b3o chain A

3D model

Region: 83 - 275
Aligned: 181
Modelled: 192
Confidence: 100.0%
Identity: 24%
PDB header:hydrolase
Chain: A: PDB Molecule:tyrosine-protein phosphatase, non-receptor type
PDBTitle: crystal structure of human tyrosine phosphatase shp-1

Phyre2

PDB 1a81 chain E

3D model

Region: 82 - 274
Aligned: 193
Modelled: 193
Confidence: 100.0%
Identity: 22%
PDB header:complex (transferase/peptide)
Chain: E: PDB Molecule:syk kinase;
PDBTitle: crystal structure of the tandem sh2 domain of the syk kinase bound to2 a dually tyrosine-phosphorylated itam

Phyre2

PDB 3gqi chain B

3D model

Region: 79 - 274
Aligned: 184
Modelled: 196
Confidence: 100.0%
Identity: 27%
PDB header:transferase/transferase inhibitor
Chain: B: PDB Molecule:phospholipase c-gamma-1;
PDBTitle: crystal structure of activated receptor tyrosine kinase in complex2 with substrates

Phyre2

PDB 2oq1 chain A domain 1

3D model

Region: 79 - 185
Aligned: 107
Modelled: 107
Confidence: 100.0%
Identity: 30%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2

PDB 1a81 chain A domain 1

3D model

Region: 83 - 185
Aligned: 103
Modelled: 103
Confidence: 100.0%
Identity: 31%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2

PDB 1a81 chain E domain 1

3D model

Region: 82 - 185
Aligned: 104
Modelled: 104
Confidence: 100.0%
Identity: 31%
Fold: SH2-like
Superfamily: SH2 domain
Family: SH2 domain

Phyre2

PDB 2yt6 chain A

3D model

Region: 2 - 96
Aligned: 95
Modelled: 95
Confidence: 99.8%
Identity: 29%
PDB header:cell cycle
Chain: A: PDB Molecule:adult male urinary bladder cdna, riken full-
PDBTitle: solution structure of the sh3_1 domain of yamaguchi sarcoma2 viral (v-yes) oncogene homolog 1

Phyre2
1

c1y57A_
2

c2c0iA_
3

c2fo0A_
4

c1x27F_
5

c3nhnA_
6

c2h8hA_
7

c2ablA_
8

c1oplA_
9

c1k9aB_
10

c1g83A_
11

c2oq1A_
12

c2ozoA_
13

c2shpA_
14

c3ps5A_
15

c2b3oA_
16

c1a81E_
17

c3gqiB_
18

d2oq1a1
19

d1a81a1
20

d1a81e1
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c2yt6A_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c1y57A_



100.0 41 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor
2c2c0iA_



100.0 46 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase hck;
PDBTitle: src family kinase hck with bound inhibitor a-420983
3c2fo0A_



100.0 31 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase abl1 (1b isoform);
PDBTitle: organization of the sh3-sh2 unit in active and inactive forms of the2 c-abl tyrosine kinase
4c1x27F_



100.0 48 PDB header:signaling protein
Chain: F: PDB Molecule:proto-oncogene tyrosine-protein kinase lck;
PDBTitle: crystal structure of lck sh2-sh3 with sh2 binding site of2 p130cas
5c3nhnA_



100.0 48 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase hck;
PDBTitle: crystal structure of the src-family kinase hck sh3-sh2-linker2 regulatory region
6c2h8hA_



100.0 42 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: src kinase in complex with a quinazoline inhibitor
7c2ablA_



100.0 32 PDB header:transferase
Chain: A: PDB Molecule:abl tyrosine kinase;
PDBTitle: sh3-sh2 domain fragment of human bcr-abl tyrosine kinase
8c1oplA_



100.0 29 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase;
PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase
9c1k9aB_



100.0 29 PDB header:transferase
Chain: B: PDB Molecule:carboxyl-terminal src kinase;
PDBTitle: crystal structure analysis of full-length carboxyl-terminal2 src kinase at 2.5 a resolution
10c1g83A_



100.0 46 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fyn;
PDBTitle: crystal structure of fyn sh3-sh2
11c2oq1A_



100.0 23 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase zap-70;
PDBTitle: tandem sh2 domains of zap-70 with 19-mer zeta1 peptide
12c2ozoA_



100.0 24 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase zap-70;
PDBTitle: autoinhibited intact human zap-70
13c2shpA_



100.0 22 PDB header:tyrosine phosphatase
Chain: A: PDB Molecule:shp-2;
PDBTitle: tyrosine phosphatase shp-2
14c3ps5A_



100.0 23 PDB header:hydrolase, signaling protein
Chain: A: PDB Molecule:tyrosine-protein phosphatase non-receptor type 6;
PDBTitle: crystal structure of the full-length human protein tyrosine2 phosphatase shp-1
15c2b3oA_



100.0 24 PDB header:hydrolase
Chain: A: PDB Molecule:tyrosine-protein phosphatase, non-receptor type
PDBTitle: crystal structure of human tyrosine phosphatase shp-1
16c1a81E_



100.0 22 PDB header:complex (transferase/peptide)
Chain: E: PDB Molecule:syk kinase;
PDBTitle: crystal structure of the tandem sh2 domain of the syk kinase bound to2 a dually tyrosine-phosphorylated itam
17c3gqiB_



100.0 27 PDB header:transferase/transferase inhibitor
Chain: B: PDB Molecule:phospholipase c-gamma-1;
PDBTitle: crystal structure of activated receptor tyrosine kinase in complex2 with substrates
18d2oq1a1



100.0 30 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
19d1a81a1



100.0 31 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
20d1a81e1



100.0 31 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
21c2dlyA_



not modelled 100.0 36 PDB header:transferase
Chain: A: PDB Molecule:fyn-related kinase;
PDBTitle: solution structure of the sh2 domain of murine fyn-related2 kinase
22d2oq1a2



not modelled 100.0 30 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
23d1rjaa_



not modelled 100.0 30 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
24d1blja_



not modelled 100.0 52 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
25d1lkka_



not modelled 100.0 50 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
26c2ysxA_



not modelled 100.0 33 PDB header:signaling protein
Chain: A: PDB Molecule:signaling inositol polyphosphate phosphatase
PDBTitle: solution structure of the human ship sh2 domain
27d1a81a2



not modelled 100.0 33 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
28c2eo3A_



not modelled 100.0 28 PDB header:signaling protein
Chain: A: PDB Molecule:crk-like protein;
PDBTitle: solution structure of the sh2 domain from human crk-like2 protein
29d1bkla_



not modelled 100.0 45 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
30d1qcfa2



not modelled 100.0 54 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
31d1f2fa_



not modelled 100.0 45 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
32d1a81e2



not modelled 100.0 34 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
33d1nrva_



not modelled 100.0 19 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
34d1o48a_



not modelled 100.0 44 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
35d1csya_



not modelled 100.0 32 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
36d1g83a2



not modelled 99.9 49 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
37c2el8A_



not modelled 99.9 20 PDB header:signaling protein
Chain: A: PDB Molecule:signal-transducing adaptor protein 2;
PDBTitle: solution structure of the human stap2 sh2 domain
38c2ge9A_



not modelled 99.9 30 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase btk;
PDBTitle: solution structures of the sh2 domain of bruton's tyrosine2 kinase
39c2eo6A_



not modelled 99.9 21 PDB header:signaling protein
Chain: A: PDB Molecule:b-cell linker protein;
PDBTitle: solution structure of the sh2 domain from mouse b-cell2 linker protein blnk
40c2knoA_



not modelled 99.9 29 PDB header:hydrolase
Chain: A: PDB Molecule:tensin-like c1 domain-containing phosphatase;
PDBTitle: nmr solution structure of sh2 domain of the human tensin like c12 domain containing phosphatase (tenc1)
41d2qmsa1



not modelled 99.9 22 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
42c2gsbA_



not modelled 99.9 25 PDB header:signaling protein
Chain: A: PDB Molecule:ras gtpase-activating protein 1;
PDBTitle: solution structure of the second sh2 domain of human ras2 gtpase-activating protein 1
43c1ka6A_



not modelled 99.9 23 PDB header:immune system
Chain: A: PDB Molecule:sh2 domain protein 1a;
PDBTitle: sap/sh2d1a bound to peptide n-py
44c2lqnA_



not modelled 99.9 23 PDB header:signaling protein
Chain: A: PDB Molecule:crk-like protein;
PDBTitle: solution structure of crkl
45d1d4ta_



not modelled 99.9 23 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
46d1opka2



not modelled 99.9 38 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
47d1i3za_



not modelled 99.9 33 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
48d1k9aa2



not modelled 99.9 35 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
49c3hizB_



not modelled 99.9 31 PDB header:transferase/oncoprotein
Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit
PDBTitle: crystal structure of p110alpha h1047r mutant in complex with2 nish2 of p85alpha
50c2dm0A_



not modelled 99.9 23 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase txk;
PDBTitle: solution structure of the sh2 domain of human tyrosine-2 protein kinase txk
51d2shpa2



not modelled 99.9 29 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
52d1cwea_



not modelled 99.9 51 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
53c2y3aB_



not modelled 99.9 33 PDB header:transferase
Chain: B: PDB Molecule:phosphatidylinositol 3-kinase regulatory subunit beta;
PDBTitle: crystal structure of p110beta in complex with icsh2 of p85beta and2 the drug gdc-0941
54d1luia_



not modelled 99.9 33 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
55d1fhsa_



not modelled 99.9 28 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
56c1x6cA_



not modelled 99.9 31 PDB header:signaling protein
Chain: A: PDB Molecule:tyrosine-protein phosphatase, non-receptor type
PDBTitle: solution structures of the sh2 domain of human protein-2 tyrosine phosphatase shp-1
57d1jwoa_



not modelled 99.9 25 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
58c2dlzA_



not modelled 99.9 23 PDB header:signaling protein
Chain: A: PDB Molecule:protein vav-2;
PDBTitle: solution structure of the sh2 domain of human protein vav-2
59d2izva2



not modelled 99.9 22 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
60c2crhA_



not modelled 99.9 19 PDB header:signaling protein
Chain: A: PDB Molecule:vav proto-oncogene;
PDBTitle: solution structure of the sh2 domain of human proto-2 oncogene protein vav1
61c2ekxA_



not modelled 99.9 26 PDB header:signaling protein
Chain: A: PDB Molecule:cytoplasmic tyrosine-protein kinase bmx;
PDBTitle: solution structure of the human bmx sh2 domain
62c2eobA_



not modelled 99.9 21 PDB header:hydrolase
Chain: A: PDB Molecule:1-phosphatidylinositol-4,5-bisphosphate
PDBTitle: solution structure of the second sh2 domain from rat plc2 gamma-2
63d2shpa3



not modelled 99.9 37 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
64d3c7ia1



not modelled 99.9 32 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
65d1pica_



not modelled 99.9 33 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
66d2cs0a1



not modelled 99.9 28 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
67d1ayaa_



not modelled 99.9 27 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
68d2fcia1



not modelled 99.9 19 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
69c2lctA_



not modelled 99.9 21 PDB header:signaling protein
Chain: A: PDB Molecule:proto-oncogene vav;
PDBTitle: solution structure of the vav1 sh2 domain complexed with a syk-derived2 doubly phosphorylated peptide
70d2eyva1



not modelled 99.9 30 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
71c3mazA_



not modelled 99.9 20 PDB header:signaling protein
Chain: A: PDB Molecule:signal-transducing adaptor protein 1;
PDBTitle: crystal structure of the human brdg1/stap-1 sh2 domain in complex with2 the ntal ptyr136 peptide
72c2vifA_



not modelled 99.9 22 PDB header:signaling protein
Chain: A: PDB Molecule:suppressor of cytokine signalling 6;
PDBTitle: crystal structure of socs6 sh2 domain in complex with a c-kit2 phosphopeptide
73d1qada_



not modelled 99.9 33 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
74c2izvA_



not modelled 99.9 22 PDB header:transcription
Chain: A: PDB Molecule:suppressor of cytokine signaling 4;
PDBTitle: crystal structure of socs-4 in complex with elongin-b and2 elongin-c at 2.55a resolution
75c2c9wA_



not modelled 99.9 23 PDB header:transcription regulation
Chain: A: PDB Molecule:suppressor of cytokine signaling 2;
PDBTitle: crystal structure of socs-2 in complex with elongin-b and2 elongin-c at 1.9a resolution
76d1jyra_



not modelled 99.9 34 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
77d1r1qa_



not modelled 99.9 34 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
78c2ci8A_



not modelled 99.9 27 PDB header:translation
Chain: A: PDB Molecule:cytoplasmic protein nck1;
PDBTitle: sh2 domain of human nck1 adaptor protein - uncomplexed
79c2hmhA_



not modelled 99.9 23 PDB header:cytokine regulator
Chain: A: PDB Molecule:suppressor of cytokine signaling 3;
PDBTitle: crystal structure of socs3 in complex with gp130(ptyr757)2 phosphopeptide.
80d1mila_



not modelled 99.9 23 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
81c2dcrA_



not modelled 99.9 23 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fes/fps;
PDBTitle: fully automated solution structure determination of the fes2 sh2 domain
82d1xa6a2



not modelled 99.9 28 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
83d2c9wa2



not modelled 99.9 21 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
84c2kk6A_



not modelled 99.9 31 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fer;
PDBTitle: solution structure of sh2 domain of proto-oncogene tyrosine-2 protein kinase fer from homo sapiens, northeast structural3 genomics consortium (nesg) target hr3461d
85c3or8A_



not modelled 99.9 17 PDB header:transcription
Chain: A: PDB Molecule:transcription elongation factor spt6;
PDBTitle: a tandem sh2 domain in transcription elongation factor spt6
86c1rqqC_



not modelled 99.8 30 PDB header:transferase/signaling protein
Chain: C: PDB Molecule:adaptor protein aps;
PDBTitle: crystal structure of the insulin receptor kinase in complex2 with the sh2 domain of aps
87d1fu6a_



not modelled 99.8 28 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
88c2yt6A_



99.8 29 PDB header:cell cycle
Chain: A: PDB Molecule:adult male urinary bladder cdna, riken full-
PDBTitle: solution structure of the sh3_1 domain of yamaguchi sarcoma2 viral (v-yes) oncogene homolog 1
89d1rpya_



not modelled 99.8 29 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
90c2cr4A_



not modelled 99.8 21 PDB header:signaling protein
Chain: A: PDB Molecule:sh3 domain-binding protein 2;
PDBTitle: solution structure of the sh2 domain of human sh3bp2 protein
91c1griA_



not modelled 99.8 29 PDB header:signal transduction adaptor
Chain: A: PDB Molecule:growth factor bound protein 2;
PDBTitle: grb2
92c2eyzA_



not modelled 99.8 24 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform ii
93c2dvjA_



not modelled 99.8 24 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog,
PDBTitle: phosphorylated crk-ii
94c3gxxB_



not modelled 99.8 17 PDB header:transcription
Chain: B: PDB Molecule:transcription elongation factor spt6;
PDBTitle: structure of the sh2 domain of the candida glabrata2 transcription elongation factor spt6, crystal form b
95c2xp1A_



not modelled 99.8 14 PDB header:transcription
Chain: A: PDB Molecule:spt6;
PDBTitle: structure of the tandem sh2 domains from antonospora locustae2 transcription elongation factor spt6
96c2eyyA_



not modelled 99.8 24 PDB header:signaling protein
Chain: A: PDB Molecule:v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform i
97c3qwyA_



not modelled 99.8 31 PDB header:signaling protein
Chain: A: PDB Molecule:cell death abnormality protein 2;
PDBTitle: ced-2
98c2dx0B_



not modelled 99.8 41 PDB header:hydrolase
Chain: B: PDB Molecule:phospholipase c, gamma 2;
PDBTitle: crystal structure of the n-terminal sh2 domain of mouse2 phospholipase c-gamma 2
99c3qwxX_



not modelled 99.8 29 PDB header:signaling protein
Chain: X: PDB Molecule:cell death abnormality protein 2;
PDBTitle: ced-2 1-174
100c2cudA_



not modelled 99.8 88 PDB header:signaling protein
Chain: A: PDB Molecule:src-like-adapter;
PDBTitle: solution structure of the sh3 domain of the human src-like2 adopter protein (slap)
101c1mv3A_



not modelled 99.7 15 PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:myc box dependent interacting protein 1;
PDBTitle: nmr structure of the tumor suppressor bin1: alternative2 splicing in melanoma and interaction with c-myc
102c2jxbA_



not modelled 99.7 18 PDB header:signaling protein complex
Chain: A: PDB Molecule:t-cell surface glycoprotein cd3 epsilon chain,
PDBTitle: structure of cd3epsilon-nck2 first sh3 domain complex
103c2oi3A_



not modelled 99.7 32 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase hck;
PDBTitle: nmr structure analysis of the hematopoetic cell kinase sh32 domain complexed with an artificial high affinity ligand3 (pd1)
104c1x6gA_



not modelled 99.6 11 PDB header:signaling protein
Chain: A: PDB Molecule:megakaryocyte-associated tyrosine-protein kinase;
PDBTitle: solution structures of the sh3 domain of human2 megakaryocyte-associated tyrosine-protein kinase.
105c2yupA_



not modelled 99.6 18 PDB header:cell adhesion
Chain: A: PDB Molecule:vinexin;
PDBTitle: solution structure of the second sh3 domain of human vinexin
106c2rqrA_



not modelled 99.6 8 PDB header:protein binding
Chain: A: PDB Molecule:engulfment and cell motility protein 1, linker, dedicator
PDBTitle: the solution structure of human dock2 sh3 domain - elmo1 peptide2 chimera complex
107d1ng2a2



not modelled 99.6 23 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
108d1lcka1



not modelled 99.6 38 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
109d2iima1



not modelled 99.6 37 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain
110c1x6bA_



not modelled 99.6 11 PDB header:signaling protein
Chain: A: PDB Molecule:rho guanine exchange factor (gef) 16;
PDBTitle: solution structures of the sh3 domain of human rho guanine2 exchange factor (gef) 16
111c2fpeB_



not modelled 99.6 15 PDB header:signaling protein
Chain: B: PDB Molecule:c-jun-amino-terminal kinase interacting protein
PDBTitle: conserved dimerization of the ib1 src-homology 3 domain
112c2kymA_



not modelled 99.6 19 PDB header:signaling protein
Chain: A: PDB Molecule:bud emergence protein 1;
PDBTitle: solution structure of the bem1p sh3-ci domain from l.elongisporus in2 complex with ste20p peptide
113c2e5kA_



not modelled 99.6 15 PDB header:protein binding
Chain: A: PDB Molecule:suppressor of t-cell receptor signaling 1;
PDBTitle: solution structure of sh3 domain in suppressor of t-cell2 receptor signaling 1
114c1w1fA_



not modelled 99.6 36 PDB header:sh3-domain
Chain: A: PDB Molecule:tyrosine-protein kinase lyn;
PDBTitle: sh3 domain of human lyn tyrosine kinase
115c2csqA_



not modelled 99.6 20 PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:rim binding protein 2;
PDBTitle: solution structure of the second sh3 domain of human rim-2 binding protein 2
116c1xa6A_



not modelled 99.6 32 PDB header:signaling protein
Chain: A: PDB Molecule:beta2-chimaerin;
PDBTitle: crystal structure of the human beta2-chimaerin
117c2cucA_



not modelled 99.6 28 PDB header:signaling protein
Chain: A: PDB Molecule:sh3 domain containing ring finger 2;
PDBTitle: solution structure of the sh3 domain of the mouse2 hypothetical protein sh3rf2
118c2ct3A_



not modelled 99.6 22 PDB header:signaling protein
Chain: A: PDB Molecule:vinexin;
PDBTitle: solution structure of the sh3 domain of the vinexin protein
119d1uura3



not modelled 99.6 21 Fold:SH2-like
Superfamily:SH2 domain
Family:SH2 domain
120d1wiea_



not modelled 99.6 15 Fold:SH3-like barrel
Superfamily:SH3-domain
Family:SH3-domain

Binding site prediction 

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