1 c3bxjB_
100.0
25
PDB header: signaling proteinChain: B: PDB Molecule: ras gtpase-activating protein syngap;
PDBTitle: crystal structure of the c2-gap fragment of syngap
2 d1wera_
100.0
100
Fold: GTPase activation domain, GAPSuperfamily: GTPase activation domain, GAPFamily: p120GAP domain-like
3 c3fayA_
100.0
19
PDB header: membrane proteinChain: A: PDB Molecule: ras gtpase-activating-like protein iqgap1;
PDBTitle: crystal structure of the gap-related domain of iqgap1
4 d1nf1a_
100.0
32
Fold: GTPase activation domain, GAPSuperfamily: GTPase activation domain, GAPFamily: p120GAP domain-like
5 c2b3oA_
100.0
31
PDB header: hydrolaseChain: A: PDB Molecule: tyrosine-protein phosphatase, non-receptor type
PDBTitle: crystal structure of human tyrosine phosphatase shp-1
6 c3ps5A_
100.0
30
PDB header: hydrolase, signaling proteinChain: A: PDB Molecule: tyrosine-protein phosphatase non-receptor type 6;
PDBTitle: crystal structure of the full-length human protein tyrosine2 phosphatase shp-1
7 c2shpA_
100.0
33
PDB header: tyrosine phosphataseChain: A: PDB Molecule: shp-2;
PDBTitle: tyrosine phosphatase shp-2
8 c3gqiB_
100.0
33
PDB header: transferase/transferase inhibitorChain: B: PDB Molecule: phospholipase c-gamma-1;
PDBTitle: crystal structure of activated receptor tyrosine kinase in complex2 with substrates
9 c2oq1A_
100.0
25
PDB header: transferaseChain: A: PDB Molecule: tyrosine-protein kinase zap-70;
PDBTitle: tandem sh2 domains of zap-70 with 19-mer zeta1 peptide
10 c2ozoA_
100.0
25
PDB header: transferaseChain: A: PDB Molecule: tyrosine-protein kinase zap-70;
PDBTitle: autoinhibited intact human zap-70
11 c1a81E_
100.0
26
PDB header: complex (transferase/peptide)Chain: E: PDB Molecule: syk kinase;
PDBTitle: crystal structure of the tandem sh2 domain of the syk kinase bound to2 a dually tyrosine-phosphorylated itam
12 c2fo0A_
99.9
21
PDB header: transferaseChain: A: PDB Molecule: proto-oncogene tyrosine-protein kinase abl1 (1b isoform);
PDBTitle: organization of the sh3-sh2 unit in active and inactive forms of the2 c-abl tyrosine kinase
13 c2gsbA_
99.9
97
PDB header: signaling proteinChain: A: PDB Molecule: ras gtpase-activating protein 1;
PDBTitle: solution structure of the second sh2 domain of human ras2 gtpase-activating protein 1
14 c2ablA_
99.9
23
PDB header: transferaseChain: A: PDB Molecule: abl tyrosine kinase;
PDBTitle: sh3-sh2 domain fragment of human bcr-abl tyrosine kinase
15 c1k9aB_
99.9
21
PDB header: transferaseChain: B: PDB Molecule: carboxyl-terminal src kinase;
PDBTitle: crystal structure analysis of full-length carboxyl-terminal2 src kinase at 2.5 a resolution
16 c1x27F_
99.9
21
PDB header: signaling proteinChain: F: PDB Molecule: proto-oncogene tyrosine-protein kinase lck;
PDBTitle: crystal structure of lck sh2-sh3 with sh2 binding site of2 p130cas
17 c1y57A_
99.9
25
PDB header: transferaseChain: A: PDB Molecule: proto-oncogene tyrosine-protein kinase src;
PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor
18 d2oq1a1
99.9
19
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
19 c3nhnA_
99.9
29
PDB header: transferaseChain: A: PDB Molecule: tyrosine-protein kinase hck;
PDBTitle: crystal structure of the src-family kinase hck sh3-sh2-linker2 regulatory region
20 c2h8hA_
99.9
25
PDB header: transferaseChain: A: PDB Molecule: proto-oncogene tyrosine-protein kinase src;
PDBTitle: src kinase in complex with a quinazoline inhibitor
21 c1oplA_
not modelled
99.8
22
PDB header: transferaseChain: A: PDB Molecule: proto-oncogene tyrosine-protein kinase;
PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase
22 c2eobA_
not modelled
99.8
21
PDB header: hydrolaseChain: A: PDB Molecule: 1-phosphatidylinositol-4,5-bisphosphate
PDBTitle: solution structure of the second sh2 domain from rat plc2 gamma-2
23 c2c0iA_
not modelled
99.8
27
PDB header: transferaseChain: A: PDB Molecule: tyrosine-protein kinase hck;
PDBTitle: src family kinase hck with bound inhibitor a-420983
24 c2eo6A_
not modelled
99.8
21
PDB header: signaling proteinChain: A: PDB Molecule: b-cell linker protein;
PDBTitle: solution structure of the sh2 domain from mouse b-cell2 linker protein blnk
25 c3hizB_
not modelled
99.8
25
PDB header: transferase/oncoproteinChain: B: PDB Molecule: phosphatidylinositol 3-kinase regulatory subunit
PDBTitle: crystal structure of p110alpha h1047r mutant in complex with2 nish2 of p85alpha
26 c2dlyA_
not modelled
99.8
20
PDB header: transferaseChain: A: PDB Molecule: fyn-related kinase;
PDBTitle: solution structure of the sh2 domain of murine fyn-related2 kinase
27 d1nrva_
not modelled
99.8
26
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
28 d3c7ia1
not modelled
99.8
27
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
29 d1rjaa_
not modelled
99.8
24
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
30 d1a81e2
not modelled
99.8
24
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
31 c1g83A_
not modelled
99.8
26
PDB header: transferaseChain: A: PDB Molecule: proto-oncogene tyrosine-protein kinase fyn;
PDBTitle: crystal structure of fyn sh3-sh2
32 d2shpa2
not modelled
99.8
33
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
33 d2oq1a2
not modelled
99.8
22
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
34 d1fhsa_
not modelled
99.8
24
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
35 c1ka6A_
not modelled
99.8
26
PDB header: immune systemChain: A: PDB Molecule: sh2 domain protein 1a;
PDBTitle: sap/sh2d1a bound to peptide n-py
36 d1a81a1
not modelled
99.8
23
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
37 c2y3aB_
not modelled
99.8
26
PDB header: transferaseChain: B: PDB Molecule: phosphatidylinositol 3-kinase regulatory subunit beta;
PDBTitle: crystal structure of p110beta in complex with icsh2 of p85beta and2 the drug gdc-0941
38 c2lqnA_
not modelled
99.8
26
PDB header: signaling proteinChain: A: PDB Molecule: crk-like protein;
PDBTitle: solution structure of crkl
39 c2eo3A_
not modelled
99.8
29
PDB header: signaling proteinChain: A: PDB Molecule: crk-like protein;
PDBTitle: solution structure of the sh2 domain from human crk-like2 protein
40 c2ysxA_
not modelled
99.8
27
PDB header: signaling proteinChain: A: PDB Molecule: signaling inositol polyphosphate phosphatase
PDBTitle: solution structure of the human ship sh2 domain
41 d1csya_
not modelled
99.8
22
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
42 c1x6cA_
not modelled
99.8
28
PDB header: signaling proteinChain: A: PDB Molecule: tyrosine-protein phosphatase, non-receptor type
PDBTitle: solution structures of the sh2 domain of human protein-2 tyrosine phosphatase shp-1
43 d1a81e1
not modelled
99.8
24
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
44 d1a81a2
not modelled
99.8
24
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
45 d1ayaa_
not modelled
99.8
35
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
46 d2fcia1
not modelled
99.8
27
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
47 d1i3za_
not modelled
99.8
20
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
48 d1jwoa_
not modelled
99.8
28
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
49 c2crhA_
not modelled
99.8
13
PDB header: signaling proteinChain: A: PDB Molecule: vav proto-oncogene;
PDBTitle: solution structure of the sh2 domain of human proto-2 oncogene protein vav1
50 c2ci8A_
not modelled
99.8
25
PDB header: translationChain: A: PDB Molecule: cytoplasmic protein nck1;
PDBTitle: sh2 domain of human nck1 adaptor protein - uncomplexed
51 d1d4ta_
not modelled
99.8
28
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
52 c2dlzA_
not modelled
99.8
19
PDB header: signaling proteinChain: A: PDB Molecule: protein vav-2;
PDBTitle: solution structure of the sh2 domain of human protein vav-2
53 d1blja_
not modelled
99.8
24
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
54 d1jyra_
not modelled
99.8
26
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
55 d1pica_
not modelled
99.8
25
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
56 d1o48a_
not modelled
99.8
26
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
57 d2qmsa1
not modelled
99.8
22
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
58 d1k9aa2
not modelled
99.8
27
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
59 c2ge9A_
not modelled
99.8
22
PDB header: transferaseChain: A: PDB Molecule: tyrosine-protein kinase btk;
PDBTitle: solution structures of the sh2 domain of bruton's tyrosine2 kinase
60 d1gmia_
99.8
26
Fold: C2 domain-likeSuperfamily: C2 domain (Calcium/lipid-binding domain, CaLB)Family: PLC-like (P variant)
61 d1opka2
not modelled
99.8
24
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
62 d1lkka_
not modelled
99.8
25
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
63 d2izva2
not modelled
99.8
18
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
64 c2knoA_
not modelled
99.8
21
PDB header: hydrolaseChain: A: PDB Molecule: tensin-like c1 domain-containing phosphatase;
PDBTitle: nmr solution structure of sh2 domain of the human tensin like c12 domain containing phosphatase (tenc1)
65 d1r1qa_
not modelled
99.8
29
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
66 d1f2fa_
not modelled
99.8
25
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
67 d1qcfa2
not modelled
99.8
27
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
68 c2fk9A_
99.8
26
PDB header: transferaseChain: A: PDB Molecule: protein kinase c, eta type;
PDBTitle: human protein kinase c, eta
69 d2shpa3
not modelled
99.8
39
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
70 d1g83a2
not modelled
99.8
24
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
71 d1bkla_
not modelled
99.8
25
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
72 c2lctA_
not modelled
99.8
14
PDB header: signaling proteinChain: A: PDB Molecule: proto-oncogene vav;
PDBTitle: solution structure of the vav1 sh2 domain complexed with a syk-derived2 doubly phosphorylated peptide
73 d2cjta1
99.8
19
Fold: C2 domain-likeSuperfamily: C2 domain (Calcium/lipid-binding domain, CaLB)Family: PLC-like (P variant)
74 d1luia_
not modelled
99.8
28
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
75 d2eyva1
not modelled
99.8
30
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
76 c2r09A_
99.7
32
PDB header: signaling proteinChain: A: PDB Molecule: cytohesin-3;
PDBTitle: crystal structure of autoinhibited form of grp1 arf gtpase exchange2 factor
77 c2el8A_
not modelled
99.7
20
PDB header: signaling proteinChain: A: PDB Molecule: signal-transducing adaptor protein 2;
PDBTitle: solution structure of the human stap2 sh2 domain
78 d1rpya_
not modelled
99.7
24
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
79 c3m7fB_
99.7
22
PDB header: signaling protein/ligaseChain: B: PDB Molecule: e3 ubiquitin-protein ligase nedd4;
PDBTitle: crystal structure of the nedd4 c2/grb10 sh2 complex
80 d2cs0a1
not modelled
99.7
26
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
81 c1rqqC_
not modelled
99.7
25
PDB header: transferase/signaling proteinChain: C: PDB Molecule: adaptor protein aps;
PDBTitle: crystal structure of the insulin receptor kinase in complex2 with the sh2 domain of aps
82 c2ekxA_
not modelled
99.7
22
PDB header: signaling proteinChain: A: PDB Molecule: cytoplasmic tyrosine-protein kinase bmx;
PDBTitle: solution structure of the human bmx sh2 domain
83 d2dyna_
not modelled
99.7
16
Fold: PH domain-like barrelSuperfamily: PH domain-likeFamily: Pleckstrin-homology domain (PH domain)
84 c2c9wA_
not modelled
99.7
18
PDB header: transcription regulationChain: A: PDB Molecule: suppressor of cytokine signaling 2;
PDBTitle: crystal structure of socs-2 in complex with elongin-b and2 elongin-c at 1.9a resolution
85 c2vifA_
not modelled
99.7
23
PDB header: signaling proteinChain: A: PDB Molecule: suppressor of cytokine signalling 6;
PDBTitle: crystal structure of socs6 sh2 domain in complex with a c-kit2 phosphopeptide
86 d1mila_
not modelled
99.7
27
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
87 c2izvA_
not modelled
99.7
19
PDB header: transcriptionChain: A: PDB Molecule: suppressor of cytokine signaling 4;
PDBTitle: crystal structure of socs-4 in complex with elongin-b and2 elongin-c at 2.55a resolution
88 c3l9bA_
99.7
17
PDB header: membrane proteinChain: A: PDB Molecule: otoferlin;
PDBTitle: crystal structure of rat otoferlin c2a
89 c2d9zA_
99.7
22
PDB header: signaling proteinChain: A: PDB Molecule: protein kinase c, nu type;
PDBTitle: solution structure of the ph domain of protein kinase c, nu2 type from human
90 c2kk6A_
not modelled
99.7
33
PDB header: transferaseChain: A: PDB Molecule: proto-oncogene tyrosine-protein kinase fer;
PDBTitle: solution structure of sh2 domain of proto-oncogene tyrosine-2 protein kinase fer from homo sapiens, northeast structural3 genomics consortium (nesg) target hr3461d
91 d1fu6a_
not modelled
99.7
28
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
92 d1qada_
not modelled
99.7
27
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
93 c2dm0A_
not modelled
99.7
21
PDB header: transferaseChain: A: PDB Molecule: tyrosine-protein kinase txk;
PDBTitle: solution structure of the sh2 domain of human tyrosine-2 protein kinase txk
94 c2dvjA_
not modelled
99.7
23
PDB header: signaling proteinChain: A: PDB Molecule: v-crk sarcoma virus ct10 oncogene homolog,
PDBTitle: phosphorylated crk-ii
95 c2dcrA_
not modelled
99.7
30
PDB header: transferaseChain: A: PDB Molecule: proto-oncogene tyrosine-protein kinase fes/fps;
PDBTitle: fully automated solution structure determination of the fes2 sh2 domain
96 c2hmhA_
not modelled
99.7
17
PDB header: cytokine regulatorChain: A: PDB Molecule: suppressor of cytokine signaling 3;
PDBTitle: crystal structure of socs3 in complex with gp130(ptyr757)2 phosphopeptide.
97 c3mazA_
not modelled
99.7
19
PDB header: signaling proteinChain: A: PDB Molecule: signal-transducing adaptor protein 1;
PDBTitle: crystal structure of the human brdg1/stap-1 sh2 domain in complex with2 the ntal ptyr136 peptide
98 d2cjsa1
99.7
21
Fold: C2 domain-likeSuperfamily: C2 domain (Calcium/lipid-binding domain, CaLB)Family: PLC-like (P variant)
99 d2coaa1
not modelled
99.7
19
Fold: PH domain-like barrelSuperfamily: PH domain-likeFamily: Pleckstrin-homology domain (PH domain)
100 c3qwxX_
not modelled
99.7
17
PDB header: signaling proteinChain: X: PDB Molecule: cell death abnormality protein 2;
PDBTitle: ced-2 1-174
101 d2fjla1
99.7
22
Fold: PH domain-like barrelSuperfamily: PH domain-likeFamily: Pleckstrin-homology domain (PH domain)
102 d1v88a_
not modelled
99.7
18
Fold: PH domain-like barrelSuperfamily: PH domain-likeFamily: Pleckstrin-homology domain (PH domain)
103 c3a8qB_
99.7
23
PDB header: signaling proteinChain: B: PDB Molecule: t-lymphoma invasion and metastasis-inducing
PDBTitle: low-resolution crystal structure of the tiam2 phccex domain
104 d1cwea_
not modelled
99.7
26
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
105 c2eyyA_
not modelled
99.7
18
PDB header: signaling proteinChain: A: PDB Molecule: v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform i
106 d1wg7a_
99.7
26
Fold: PH domain-like barrelSuperfamily: PH domain-likeFamily: Pleckstrin-homology domain (PH domain)
107 d1xa6a2
not modelled
99.7
24
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
108 d1x1ga1
99.7
25
Fold: PH domain-like barrelSuperfamily: PH domain-likeFamily: Pleckstrin-homology domain (PH domain)
109 c2eyzA_
not modelled
99.7
29
PDB header: signaling proteinChain: A: PDB Molecule: v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform ii
110 d1x1fa1
not modelled
99.7
18
Fold: PH domain-like barrelSuperfamily: PH domain-likeFamily: Pleckstrin-homology domain (PH domain)
111 c3or8A_
not modelled
99.7
20
PDB header: transcriptionChain: A: PDB Molecule: transcription elongation factor spt6;
PDBTitle: a tandem sh2 domain in transcription elongation factor spt6
112 d2c9wa2
not modelled
99.7
18
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
113 c3qwyA_
not modelled
99.7
17
PDB header: signaling proteinChain: A: PDB Molecule: cell death abnormality protein 2;
PDBTitle: ced-2
114 c2d9vA_
not modelled
99.7
19
PDB header: membrane proteinChain: A: PDB Molecule: pleckstrin homology domain-containing protein
PDBTitle: solution structure of the ph domain of pleckstrin homology2 domain-containing protein family b member 1 from mouse
115 d1u5ea1
not modelled
99.7
25
Fold: PH domain-like barrelSuperfamily: PH domain-likeFamily: Pleckstrin-homology domain (PH domain)
116 d1xx0a1
not modelled
99.7
32
Fold: PH domain-like barrelSuperfamily: PH domain-likeFamily: Pleckstrin-homology domain (PH domain)
117 c3a8nA_
not modelled
99.7
22
PDB header: signaling proteinChain: A: PDB Molecule: t-lymphoma invasion and metastasis-inducing
PDBTitle: crystal structure of the tiam1 phccex domain
118 d2coca1
not modelled
99.6
15
Fold: PH domain-like barrelSuperfamily: PH domain-likeFamily: Pleckstrin-homology domain (PH domain)
119 c2xp1A_
not modelled
99.6
19
PDB header: transcriptionChain: A: PDB Molecule: spt6;
PDBTitle: structure of the tandem sh2 domains from antonospora locustae2 transcription elongation factor spt6
120 c2ys3A_
not modelled
99.6
21
PDB header: signaling proteinChain: A: PDB Molecule: unc-112-related protein 2;
PDBTitle: solution structure of the ph domain of kindlin-3 from human