1 c3ohmB_
100.0
35
PDB header: signaling protein / hydrolaseChain: B: PDB Molecule: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase
PDBTitle: crystal structure of activated g alpha q bound to its effector2 phospholipase c beta 3
2 c3qr0A_
100.0
35
PDB header: hydrolaseChain: A: PDB Molecule: phospholipase c-beta (plc-beta);
PDBTitle: crystal structure of s. officinalis plc21
3 c2fjuB_
100.0
35
PDB header: signaling protein,apoptosis/hydrolaseChain: B: PDB Molecule: 1-phosphatidylinositol-4,5-bisphosphate
PDBTitle: activated rac1 bound to its effector phospholipase c beta 2
4 c1djyB_
100.0
44
PDB header: lipid degradationChain: B: PDB Molecule: phosphoinositide-specific phospholipase c,
PDBTitle: phosphoinositide-specific phospholipase c-delta1 from rat2 complexed with inositol-2,4,5-trisphosphate
5 d2zkmx4
100.0
54
Fold: TIM beta/alpha-barrelSuperfamily: PLC-like phosphodiesterasesFamily: Mammalian PLC
6 d1qasa3
100.0
59
Fold: TIM beta/alpha-barrelSuperfamily: PLC-like phosphodiesterasesFamily: Mammalian PLC
7 c3gqiB_
100.0
62
PDB header: transferase/transferase inhibitorChain: B: PDB Molecule: phospholipase c-gamma-1;
PDBTitle: crystal structure of activated receptor tyrosine kinase in complex2 with substrates
8 c2b3oA_
100.0
24
PDB header: hydrolaseChain: A: PDB Molecule: tyrosine-protein phosphatase, non-receptor type
PDBTitle: crystal structure of human tyrosine phosphatase shp-1
9 c2shpA_
100.0
31
PDB header: tyrosine phosphataseChain: A: PDB Molecule: shp-2;
PDBTitle: tyrosine phosphatase shp-2
10 c3ps5A_
100.0
26
PDB header: hydrolase, signaling proteinChain: A: PDB Molecule: tyrosine-protein phosphatase non-receptor type 6;
PDBTitle: crystal structure of the full-length human protein tyrosine2 phosphatase shp-1
11 d2zkmx2
100.0
31
Fold: C2 domain-likeSuperfamily: C2 domain (Calcium/lipid-binding domain, CaLB)Family: PLC-like (P variant)
12 d1qasa2
100.0
31
Fold: C2 domain-likeSuperfamily: C2 domain (Calcium/lipid-binding domain, CaLB)Family: PLC-like (P variant)
13 c2lqnA_
100.0
19
PDB header: signaling proteinChain: A: PDB Molecule: crk-like protein;
PDBTitle: solution structure of crkl
14 c2oq1A_
99.9
26
PDB header: transferaseChain: A: PDB Molecule: tyrosine-protein kinase zap-70;
PDBTitle: tandem sh2 domains of zap-70 with 19-mer zeta1 peptide
15 c2ozoA_
99.9
24
PDB header: transferaseChain: A: PDB Molecule: tyrosine-protein kinase zap-70;
PDBTitle: autoinhibited intact human zap-70
16 c1a81E_
99.9
26
PDB header: complex (transferase/peptide)Chain: E: PDB Molecule: syk kinase;
PDBTitle: crystal structure of the tandem sh2 domain of the syk kinase bound to2 a dually tyrosine-phosphorylated itam
17 c2eyzA_
99.9
19
PDB header: signaling proteinChain: A: PDB Molecule: v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform ii
18 d2zkmx3
99.9
18
Fold: PH domain-like barrelSuperfamily: PH domain-likeFamily: Pleckstrin-homology domain (PH domain)
19 c2eyyA_
99.9
27
PDB header: signaling proteinChain: A: PDB Molecule: v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform i
20 c2dvjA_
99.8
26
PDB header: signaling proteinChain: A: PDB Molecule: v-crk sarcoma virus ct10 oncogene homolog,
PDBTitle: phosphorylated crk-ii
21 c3qwxX_
not modelled
99.8
27
PDB header: signaling proteinChain: X: PDB Molecule: cell death abnormality protein 2;
PDBTitle: ced-2 1-174
22 c3qwyA_
not modelled
99.8
27
PDB header: signaling proteinChain: A: PDB Molecule: cell death abnormality protein 2;
PDBTitle: ced-2
23 d2zkmx1
not modelled
99.8
17
Fold: EF Hand-likeSuperfamily: EF-handFamily: EF-hand modules in multidomain proteins
24 c3h4wA_
not modelled
99.8
21
PDB header: hydrolaseChain: A: PDB Molecule: phosphatidylinositol-specific phospholipase c1;
PDBTitle: structure of a ca+2 dependent phosphatidylinositol-specific2 phospholipase c (pi-plc) enzyme from streptomyces antibioticus
25 d1djxb1
not modelled
99.8
25
Fold: EF Hand-likeSuperfamily: EF-handFamily: EF-hand modules in multidomain proteins
26 c2fjlA_
not modelled
99.8
41
PDB header: hydrolaseChain: A: PDB Molecule: 1-phosphatidylinositol-4,5-bisphosphate
PDBTitle: solution structure of the split ph domain in phospholipase2 c-gamma1
27 d1maia_
not modelled
99.7
25
Fold: PH domain-like barrelSuperfamily: PH domain-likeFamily: Pleckstrin-homology domain (PH domain)
28 c2eobA_
not modelled
99.7
92
PDB header: hydrolaseChain: A: PDB Molecule: 1-phosphatidylinositol-4,5-bisphosphate
PDBTitle: solution structure of the second sh2 domain from rat plc2 gamma-2
29 d1qasa1
not modelled
99.7
20
Fold: EF Hand-likeSuperfamily: EF-handFamily: EF-hand modules in multidomain proteins
30 c3or8A_
not modelled
99.7
13
PDB header: transcriptionChain: A: PDB Molecule: transcription elongation factor spt6;
PDBTitle: a tandem sh2 domain in transcription elongation factor spt6
31 c2vszA_
not modelled
99.6
22
PDB header: apoptosisChain: A: PDB Molecule: engulfment and cell motility protein 1;
PDBTitle: crystal structure of the elmo1 ph domain
32 c2xp1A_
not modelled
99.6
20
PDB header: transcriptionChain: A: PDB Molecule: spt6;
PDBTitle: structure of the tandem sh2 domains from antonospora locustae2 transcription elongation factor spt6
33 c2gsbA_
not modelled
99.5
23
PDB header: signaling proteinChain: A: PDB Molecule: ras gtpase-activating protein 1;
PDBTitle: solution structure of the second sh2 domain of human ras2 gtpase-activating protein 1
34 c2dx0B_
not modelled
99.5
92
PDB header: hydrolaseChain: B: PDB Molecule: phospholipase c, gamma 2;
PDBTitle: crystal structure of the n-terminal sh2 domain of mouse2 phospholipase c-gamma 2
35 d2fcia1
not modelled
99.5
64
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
36 c2y3aB_
not modelled
99.5
38
PDB header: transferaseChain: B: PDB Molecule: phosphatidylinositol 3-kinase regulatory subunit beta;
PDBTitle: crystal structure of p110beta in complex with icsh2 of p85beta and2 the drug gdc-0941
37 c2eo6A_
not modelled
99.4
36
PDB header: signaling proteinChain: A: PDB Molecule: b-cell linker protein;
PDBTitle: solution structure of the sh2 domain from mouse b-cell2 linker protein blnk
38 c2nq3A_
not modelled
99.4
21
PDB header: ligaseChain: A: PDB Molecule: itchy homolog e3 ubiquitin protein ligase;
PDBTitle: crystal structure of the c2 domain of human itchy homolog2 e3 ubiquitin protein ligase
39 d2nq3a1
not modelled
99.4
21
Fold: C2 domain-likeSuperfamily: C2 domain (Calcium/lipid-binding domain, CaLB)Family: PLC-like (P variant)
40 c2dmhA_
not modelled
99.4
23
PDB header: lipid binding proteinChain: A: PDB Molecule: myoferlin;
PDBTitle: solution structure of the first c2 domain of human myoferlin
41 d1gmia_
not modelled
99.4
17
Fold: C2 domain-likeSuperfamily: C2 domain (Calcium/lipid-binding domain, CaLB)Family: PLC-like (P variant)
42 d2r83a1
not modelled
99.4
22
Fold: C2 domain-likeSuperfamily: C2 domain (Calcium/lipid-binding domain, CaLB)Family: Synaptotagmin-like (S variant)
43 c3hizB_
not modelled
99.4
29
PDB header: transferase/oncoproteinChain: B: PDB Molecule: phosphatidylinositol 3-kinase regulatory subunit
PDBTitle: crystal structure of p110alpha h1047r mutant in complex with2 nish2 of p85alpha
44 c2q3xA_
not modelled
99.4
21
PDB header: transport proteinChain: A: PDB Molecule: regulating synaptic membrane exocytosis protein 1;
PDBTitle: the rim1alpha c2b domain
45 d1rlwa_
not modelled
99.4
20
Fold: C2 domain-likeSuperfamily: C2 domain (Calcium/lipid-binding domain, CaLB)Family: PLC-like (P variant)
46 d1csya_
not modelled
99.4
28
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
47 c3nsjA_
not modelled
99.4
23
PDB header: immune systemChain: A: PDB Molecule: perforin-1;
PDBTitle: the x-ray crystal structure of lymphocyte perforin
48 d2oq1a1
not modelled
99.4
25
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
49 c3l9bA_
not modelled
99.4
15
PDB header: membrane proteinChain: A: PDB Molecule: otoferlin;
PDBTitle: crystal structure of rat otoferlin c2a
50 d1nrva_
not modelled
99.4
21
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
51 c3m7fB_
not modelled
99.3
19
PDB header: signaling protein/ligaseChain: B: PDB Molecule: e3 ubiquitin-protein ligase nedd4;
PDBTitle: crystal structure of the nedd4 c2/grb10 sh2 complex
52 c2chdA_
not modelled
99.3
23
PDB header: protein transportChain: A: PDB Molecule: rabphilin-3a;
PDBTitle: crystal structure of the c2a domain of rabphilin-3a
53 c3kwtA_
not modelled
99.3
18
PDB header: metal binding proteinChain: A: PDB Molecule: munc13-1;
PDBTitle: munc13-1 c2b-domain, calcium-free
54 d1a81e2
not modelled
99.3
31
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
55 d2oq1a2
not modelled
99.3
30
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
56 d1luia_
not modelled
99.3
30
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
57 d1pica_
not modelled
99.3
34
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
58 d2shpa2
not modelled
99.3
31
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
59 c3fbkB_
not modelled
99.3
15
PDB header: signaling proteinChain: B: PDB Molecule: regulator of g-protein signaling 3;
PDBTitle: crystal structure of the c2 domain of the human regulator2 of g-protein signaling 3 isoform 6 (rgp3), northeast3 structural genomics consortium target hr5550a
60 c1x6cA_
not modelled
99.3
27
PDB header: signaling proteinChain: A: PDB Molecule: tyrosine-protein phosphatase, non-receptor type
PDBTitle: solution structures of the sh2 domain of human protein-2 tyrosine phosphatase shp-1
61 c2dlzA_
not modelled
99.3
19
PDB header: signaling proteinChain: A: PDB Molecule: protein vav-2;
PDBTitle: solution structure of the sh2 domain of human protein vav-2
62 d1ayaa_
not modelled
99.3
31
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
63 d1a81a1
not modelled
99.3
18
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
64 c2el8A_
not modelled
99.3
27
PDB header: signaling proteinChain: A: PDB Molecule: signal-transducing adaptor protein 2;
PDBTitle: solution structure of the human stap2 sh2 domain
65 d2qmsa1
not modelled
99.3
27
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
66 d1a81a2
not modelled
99.3
32
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
67 d1dsya_
not modelled
99.3
20
Fold: C2 domain-likeSuperfamily: C2 domain (Calcium/lipid-binding domain, CaLB)Family: Synaptotagmin-like (S variant)
68 d3c7ia1
not modelled
99.3
32
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
69 c2dlyA_
not modelled
99.3
26
PDB header: transferaseChain: A: PDB Molecule: fyn-related kinase;
PDBTitle: solution structure of the sh2 domain of murine fyn-related2 kinase
70 d1a25a_
not modelled
99.2
20
Fold: C2 domain-likeSuperfamily: C2 domain (Calcium/lipid-binding domain, CaLB)Family: Synaptotagmin-like (S variant)
71 d1rjaa_
not modelled
99.2
37
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
72 c2ysxA_
not modelled
99.2
30
PDB header: signaling proteinChain: A: PDB Molecule: signaling inositol polyphosphate phosphatase
PDBTitle: solution structure of the human ship sh2 domain
73 d1k9aa2
not modelled
99.2
29
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
74 c1ka6A_
not modelled
99.2
22
PDB header: immune systemChain: A: PDB Molecule: sh2 domain protein 1a;
PDBTitle: sap/sh2d1a bound to peptide n-py
75 c1griA_
not modelled
99.2
31
PDB header: signal transduction adaptorChain: A: PDB Molecule: growth factor bound protein 2;
PDBTitle: grb2
76 d1fhsa_
not modelled
99.2
30
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
77 c3jzyA_
not modelled
99.2
21
PDB header: endocytosisChain: A: PDB Molecule: intersectin 2;
PDBTitle: crystal structure of human intersectin 2 c2 domain
78 c2fo0A_
not modelled
99.2
24
PDB header: transferaseChain: A: PDB Molecule: proto-oncogene tyrosine-protein kinase abl1 (1b isoform);
PDBTitle: organization of the sh3-sh2 unit in active and inactive forms of the2 c-abl tyrosine kinase
79 c2fk9A_
not modelled
99.2
20
PDB header: transferaseChain: A: PDB Molecule: protein kinase c, eta type;
PDBTitle: human protein kinase c, eta
80 c3a98B_
not modelled
99.2
21
PDB header: signaling proteinChain: B: PDB Molecule: engulfment and cell motility protein 1;
PDBTitle: crystal structure of the complex of the interacting regions of dock22 and elmo1
81 d2izva2
not modelled
99.2
21
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
82 d1a81e1
not modelled
99.2
24
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
83 c2crhA_
not modelled
99.2
29
PDB header: signaling proteinChain: A: PDB Molecule: vav proto-oncogene;
PDBTitle: solution structure of the sh2 domain of human proto-2 oncogene protein vav1
84 d1blja_
not modelled
99.2
25
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
85 c1k9aB_
not modelled
99.2
29
PDB header: transferaseChain: B: PDB Molecule: carboxyl-terminal src kinase;
PDBTitle: crystal structure analysis of full-length carboxyl-terminal2 src kinase at 2.5 a resolution
86 c2ge9A_
not modelled
99.2
25
PDB header: transferaseChain: A: PDB Molecule: tyrosine-protein kinase btk;
PDBTitle: solution structures of the sh2 domain of bruton's tyrosine2 kinase
87 c2z0uB_
not modelled
99.2
16
PDB header: lipid binding proteinChain: B: PDB Molecule: ww domain-containing protein 1;
PDBTitle: crystal structure of c2 domain of kibra protein
88 d1ugka_
not modelled
99.2
19
Fold: C2 domain-likeSuperfamily: C2 domain (Calcium/lipid-binding domain, CaLB)Family: Synaptotagmin-like (S variant)
89 c2ekxA_
not modelled
99.2
26
PDB header: signaling proteinChain: A: PDB Molecule: cytoplasmic tyrosine-protein kinase bmx;
PDBTitle: solution structure of the human bmx sh2 domain
90 d1xa6a2
not modelled
99.2
23
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
91 d1i3za_
not modelled
99.2
28
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
92 d1qada_
not modelled
99.2
39
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
93 c2ci8A_
not modelled
99.2
30
PDB header: translationChain: A: PDB Molecule: cytoplasmic protein nck1;
PDBTitle: sh2 domain of human nck1 adaptor protein - uncomplexed
94 c2eo3A_
not modelled
99.2
32
PDB header: signaling proteinChain: A: PDB Molecule: crk-like protein;
PDBTitle: solution structure of the sh2 domain from human crk-like2 protein
95 c2nsqA_
not modelled
99.2
22
PDB header: ligaseChain: A: PDB Molecule: e3 ubiquitin-protein ligase nedd4-like protein;
PDBTitle: crystal structure of the c2 domain of the human e3 ubiquitin-protein2 ligase nedd4-like protein
96 d2cs0a1
not modelled
99.2
27
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
97 d1d4ta_
not modelled
99.2
23
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
98 d1jyra_
not modelled
99.2
31
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
99 c2lctA_
not modelled
99.2
29
PDB header: signaling proteinChain: A: PDB Molecule: proto-oncogene vav;
PDBTitle: solution structure of the vav1 sh2 domain complexed with a syk-derived2 doubly phosphorylated peptide
100 d2ep6a1
not modelled
99.2
29
Fold: C2 domain-likeSuperfamily: C2 domain (Calcium/lipid-binding domain, CaLB)Family: PLC-like (P variant)
101 c2enpA_
not modelled
99.2
28
PDB header: transport proteinChain: A: PDB Molecule: b/k protein;
PDBTitle: solution structure of the first c2 domain from human b/k2 protein
102 c2cr4A_
not modelled
99.2
20
PDB header: signaling proteinChain: A: PDB Molecule: sh3 domain-binding protein 2;
PDBTitle: solution structure of the sh2 domain of human sh3bp2 protein
103 c2jqzA_
not modelled
99.2
21
PDB header: ligaseChain: A: PDB Molecule: e3 ubiquitin-protein ligase smurf2;
PDBTitle: solution structure of the c2 domain of human smurf2
104 c2b3rA_
not modelled
99.1
19
PDB header: transferaseChain: A: PDB Molecule: phosphatidylinositol-4-phosphate 3-kinase c2 domain-
PDBTitle: crystal structure of the c2 domain of class ii phosphatidylinositide2 3-kinase c2
105 c1dqvA_
not modelled
99.1
26
PDB header: endocytosis/exocytosisChain: A: PDB Molecule: synaptotagmin iii;
PDBTitle: crystal structure of synaptotagmin iii c2a/c2b
106 d1jwoa_
not modelled
99.1
25
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
107 d1fu6a_
not modelled
99.1
32
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
108 c2ablA_
not modelled
99.1
27
PDB header: transferaseChain: A: PDB Molecule: abl tyrosine kinase;
PDBTitle: sh3-sh2 domain fragment of human bcr-abl tyrosine kinase
109 d1rsya_
not modelled
99.1
29
Fold: C2 domain-likeSuperfamily: C2 domain (Calcium/lipid-binding domain, CaLB)Family: Synaptotagmin-like (S variant)
110 d1wfma_
not modelled
99.1
16
Fold: C2 domain-likeSuperfamily: C2 domain (Calcium/lipid-binding domain, CaLB)Family: Synaptotagmin-like (S variant)
111 d1opka2
not modelled
99.1
29
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
112 d1qcfa2
not modelled
99.1
26
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
113 c2d8kA_
not modelled
99.1
28
PDB header: endocytosis/exocytosisChain: A: PDB Molecule: synaptotagmin vii;
PDBTitle: solution structure of the first c2 domain of synaptotagmin2 vii
114 d2shpa3
not modelled
99.1
30
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
115 d2eyva1
not modelled
99.1
33
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
116 c2kk6A_
not modelled
99.1
29
PDB header: transferaseChain: A: PDB Molecule: proto-oncogene tyrosine-protein kinase fer;
PDBTitle: solution structure of sh2 domain of proto-oncogene tyrosine-2 protein kinase fer from homo sapiens, northeast structural3 genomics consortium (nesg) target hr3461d
117 d1mila_
not modelled
99.1
31
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
118 c2r83B_
not modelled
99.1
25
PDB header: endocytosis, exocytosisChain: B: PDB Molecule: synaptotagmin-1;
PDBTitle: crystal structure analysis of human synaptotagmin 1 c2a-c2b
119 c2dcrA_
not modelled
99.1
22
PDB header: transferaseChain: A: PDB Molecule: proto-oncogene tyrosine-protein kinase fes/fps;
PDBTitle: fully automated solution structure determination of the fes2 sh2 domain
120 c3nhnA_
not modelled
99.1
30
PDB header: transferaseChain: A: PDB Molecule: tyrosine-protein kinase hck;
PDBTitle: crystal structure of the src-family kinase hck sh3-sh2-linker2 regulatory region