1 c1xa6A_
100.0
44
PDB header: signaling proteinChain: A: PDB Molecule: beta2-chimaerin;
PDBTitle: crystal structure of the human beta2-chimaerin
2 c3byiA_
100.0
26
PDB header: signaling proteinChain: A: PDB Molecule: rho gtpase activating protein 15;
PDBTitle: crystal structure of human rho gtpase activating protein 15 (arhgap15)
3 d1xa6a1
100.0
41
Fold: GTPase activation domain, GAPSuperfamily: GTPase activation domain, GAPFamily: BCR-homology GTPase activation domain (BH-domain)
4 c3iugA_
100.0
30
PDB header: splicingChain: A: PDB Molecule: rho/cdc42/rac gtpase-activating protein rics;
PDBTitle: crystal structure of the rhogap domain of rics
5 c3fk2B_
100.0
30
PDB header: signaling protein, hydrolase activatorChain: B: PDB Molecule: glucocorticoid receptor dna-binding factor 1;
PDBTitle: crystal structure of the rhogap domain of human2 glucocorticoid receptor dna-binding factor 1
6 c2ngrB_
100.0
24
PDB header: hydrolaseChain: B: PDB Molecule: protein (gtpase activating protein (rhg));
PDBTitle: transition state complex for gtp hydrolysis by cdc42:2 comparisons of the high resolution structures for cdc423 bound to the active and catalytically compromised forms of4 the cdc42-gap.
7 c2ee5A_
100.0
28
PDB header: hydrolaseChain: A: PDB Molecule: rho gtpase activating protein 5 variant;
PDBTitle: solution structure of the n-teruminus extended rhogap2 domain from human rho gtpase activating protein 5 variant
8 d1tx4a_
100.0
24
Fold: GTPase activation domain, GAPSuperfamily: GTPase activation domain, GAPFamily: BCR-homology GTPase activation domain (BH-domain)
9 c3msxB_
100.0
25
PDB header: protein bindingChain: B: PDB Molecule: rho gtpase-activating protein 20;
PDBTitle: crystal structure of rhoa.gdp.mgf3 in complex with gap domain of2 arhgap20
10 c3kuqA_
100.0
25
PDB header: hydrolase activatorChain: A: PDB Molecule: rho gtpase-activating protein 7;
PDBTitle: crystal structure of the dlc1 rhogap domain
11 c2ovjA_
100.0
30
PDB header: signaling proteinChain: A: PDB Molecule: rac gtpase-activating protein 1;
PDBTitle: the crystal structure of the human rac gtpase activating protein 12 (racgap1) mgcracgap.
12 c1f7cA_
100.0
29
PDB header: signaling proteinChain: A: PDB Molecule: rhogap protein;
PDBTitle: crystal structure of the bh domain from graf, the gtpase2 regulator associated with focal adhesion kinase
13 d1f7ca_
100.0
29
Fold: GTPase activation domain, GAPSuperfamily: GTPase activation domain, GAPFamily: BCR-homology GTPase activation domain (BH-domain)
14 c3qisA_
100.0
21
PDB header: hydrolase/protein bindingChain: A: PDB Molecule: inositol polyphosphate 5-phosphatase ocrl-1;
PDBTitle: recognition of the f&h motif by the lowe syndrome protein ocrl
15 c3eapD_
100.0
25
PDB header: hydrolase activatorChain: D: PDB Molecule: rho gtpase-activating protein 11a;
PDBTitle: crystal structure of the rhogap domain of arhgap11a
16 c2qv2A_
100.0
23
PDB header: hydrolaseChain: A: PDB Molecule: inositol polyphosphate 5-phosphatase ocrl-1;
PDBTitle: a role of the lowe syndrome protein ocrl in early steps of2 the endocytic pathway
17 d1pbwa_
100.0
24
Fold: GTPase activation domain, GAPSuperfamily: GTPase activation domain, GAPFamily: BCR-homology GTPase activation domain (BH-domain)
18 c1pbwB_
100.0
24
PDB header: phosphotransferaseChain: B: PDB Molecule: phosphatidylinositol 3-kinase;
PDBTitle: structure of bcr-homology (bh) domain
19 c2xs6A_
100.0
24
PDB header: transferaseChain: A: PDB Molecule: phosphatidylinositol 3-kinase regulatory subunit beta;
PDBTitle: crystal structure of the rhogap domain of human pik3r2
20 d1xa6a2
99.8
38
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
21 c3hizB_
not modelled
99.3
25
PDB header: transferase/oncoproteinChain: B: PDB Molecule: phosphatidylinositol 3-kinase regulatory subunit
PDBTitle: crystal structure of p110alpha h1047r mutant in complex with2 nish2 of p85alpha
22 c2oq1A_
not modelled
99.2
23
PDB header: transferaseChain: A: PDB Molecule: tyrosine-protein kinase zap-70;
PDBTitle: tandem sh2 domains of zap-70 with 19-mer zeta1 peptide
23 c2lqnA_
not modelled
99.2
26
PDB header: signaling proteinChain: A: PDB Molecule: crk-like protein;
PDBTitle: solution structure of crkl
24 c2eo6A_
not modelled
99.2
25
PDB header: signaling proteinChain: A: PDB Molecule: b-cell linker protein;
PDBTitle: solution structure of the sh2 domain from mouse b-cell2 linker protein blnk
25 c2ozoA_
not modelled
99.2
23
PDB header: transferaseChain: A: PDB Molecule: tyrosine-protein kinase zap-70;
PDBTitle: autoinhibited intact human zap-70
26 c2y3aB_
not modelled
99.2
22
PDB header: transferaseChain: B: PDB Molecule: phosphatidylinositol 3-kinase regulatory subunit beta;
PDBTitle: crystal structure of p110beta in complex with icsh2 of p85beta and2 the drug gdc-0941
27 c2shpA_
not modelled
99.1
30
PDB header: tyrosine phosphataseChain: A: PDB Molecule: shp-2;
PDBTitle: tyrosine phosphatase shp-2
28 d2oq1a1
not modelled
99.1
24
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
29 c2c9wA_
not modelled
99.1
25
PDB header: transcription regulationChain: A: PDB Molecule: suppressor of cytokine signaling 2;
PDBTitle: crystal structure of socs-2 in complex with elongin-b and2 elongin-c at 1.9a resolution
30 c4fl2A_
not modelled
99.1
24
PDB header: transferaseChain: A: PDB Molecule: tyrosine-protein kinase syk;
PDBTitle: structural and biophysical characterization of the syk activation2 switch
31 c2fo0A_
not modelled
99.1
32
PDB header: transferaseChain: A: PDB Molecule: proto-oncogene tyrosine-protein kinase abl1 (1b isoform);
PDBTitle: organization of the sh3-sh2 unit in active and inactive forms of the2 c-abl tyrosine kinase
32 c2vifA_
not modelled
99.1
26
PDB header: signaling proteinChain: A: PDB Molecule: suppressor of cytokine signalling 6;
PDBTitle: crystal structure of socs6 sh2 domain in complex with a c-kit2 phosphopeptide
33 c3ps5A_
not modelled
99.1
27
PDB header: hydrolase, signaling proteinChain: A: PDB Molecule: tyrosine-protein phosphatase non-receptor type 6;
PDBTitle: crystal structure of the full-length human protein tyrosine2 phosphatase shp-1
34 c2crhA_
not modelled
99.1
21
PDB header: signaling proteinChain: A: PDB Molecule: vav proto-oncogene;
PDBTitle: solution structure of the sh2 domain of human proto-2 oncogene protein vav1
35 d1fhsa_
not modelled
99.1
17
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
36 c2b3oA_
not modelled
99.1
27
PDB header: hydrolaseChain: A: PDB Molecule: tyrosine-protein phosphatase, non-receptor type
PDBTitle: crystal structure of human tyrosine phosphatase shp-1
37 c3gqiB_
not modelled
99.1
29
PDB header: transferase/transferase inhibitorChain: B: PDB Molecule: phospholipase c-gamma-1;
PDBTitle: crystal structure of activated receptor tyrosine kinase in complex2 with substrates
38 d1a81a1
not modelled
99.1
24
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
39 c2el8A_
not modelled
99.1
17
PDB header: signaling proteinChain: A: PDB Molecule: signal-transducing adaptor protein 2;
PDBTitle: solution structure of the human stap2 sh2 domain
40 d2izva2
not modelled
99.1
20
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
41 d1rpya_
not modelled
99.1
25
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
42 d2oq1a2
not modelled
99.1
30
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
43 d1k9aa2
not modelled
99.1
23
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
44 d2eyva1
not modelled
99.1
33
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
45 c2gsbA_
not modelled
99.0
18
PDB header: signaling proteinChain: A: PDB Molecule: ras gtpase-activating protein 1;
PDBTitle: solution structure of the second sh2 domain of human ras2 gtpase-activating protein 1
46 c1k9aB_
not modelled
99.0
21
PDB header: transferaseChain: B: PDB Molecule: carboxyl-terminal src kinase;
PDBTitle: crystal structure analysis of full-length carboxyl-terminal2 src kinase at 2.5 a resolution
47 c2dlyA_
not modelled
99.0
20
PDB header: transferaseChain: A: PDB Molecule: fyn-related kinase;
PDBTitle: solution structure of the sh2 domain of murine fyn-related2 kinase
48 d1rjaa_
not modelled
99.0
21
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
49 c2izvA_
not modelled
99.0
20
PDB header: transcriptionChain: A: PDB Molecule: suppressor of cytokine signaling 4;
PDBTitle: crystal structure of socs-4 in complex with elongin-b and2 elongin-c at 2.55a resolution
50 d2c9wa2
not modelled
99.0
25
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
51 c2ysxA_
not modelled
99.0
20
PDB header: signaling proteinChain: A: PDB Molecule: signaling inositol polyphosphate phosphatase
PDBTitle: solution structure of the human ship sh2 domain
52 c1oplA_
not modelled
99.0
32
PDB header: transferaseChain: A: PDB Molecule: proto-oncogene tyrosine-protein kinase;
PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase
53 d1a81e1
not modelled
99.0
23
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
54 d2cs0a1
not modelled
99.0
22
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
55 d1r1qa_
not modelled
99.0
18
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
56 c2dlzA_
not modelled
99.0
19
PDB header: signaling proteinChain: A: PDB Molecule: protein vav-2;
PDBTitle: solution structure of the sh2 domain of human protein vav-2
57 c2hdxB_
not modelled
99.0
25
PDB header: signaling proteinChain: B: PDB Molecule: sh2-b ph domain containing signaling mediator 1
PDBTitle: crystal structure of the src homology-2 domain of sh2-b in2 complex with jak2 ptyr813 phosphopeptide
58 c1x6cA_
not modelled
99.0
24
PDB header: signaling proteinChain: A: PDB Molecule: tyrosine-protein phosphatase, non-receptor type
PDBTitle: solution structures of the sh2 domain of human protein-2 tyrosine phosphatase shp-1
59 c2hmhA_
not modelled
99.0
19
PDB header: cytokine regulatorChain: A: PDB Molecule: suppressor of cytokine signaling 3;
PDBTitle: crystal structure of socs3 in complex with gp130(ptyr757)2 phosphopeptide.
60 d1a81a2
not modelled
99.0
24
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
61 d1nrva_
not modelled
99.0
19
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
62 d1jwoa_
not modelled
99.0
29
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
63 d1a81e2
not modelled
99.0
25
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
64 d1csya_
not modelled
99.0
25
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
65 c2eo3A_
not modelled
99.0
28
PDB header: signaling proteinChain: A: PDB Molecule: crk-like protein;
PDBTitle: solution structure of the sh2 domain from human crk-like2 protein
66 c1ka6A_
not modelled
99.0
21
PDB header: immune systemChain: A: PDB Molecule: sh2 domain protein 1a;
PDBTitle: sap/sh2d1a bound to peptide n-py
67 d1opka2
not modelled
99.0
33
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
68 d1jyra_
not modelled
99.0
20
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
69 c2ablA_
not modelled
99.0
33
PDB header: transferaseChain: A: PDB Molecule: abl tyrosine kinase;
PDBTitle: sh3-sh2 domain fragment of human bcr-abl tyrosine kinase
70 c2lctA_
not modelled
99.0
27
PDB header: signaling proteinChain: A: PDB Molecule: proto-oncogene vav;
PDBTitle: solution structure of the vav1 sh2 domain complexed with a syk-derived2 doubly phosphorylated peptide
71 c1rqqC_
not modelled
99.0
26
PDB header: transferase/signaling proteinChain: C: PDB Molecule: adaptor protein aps;
PDBTitle: crystal structure of the insulin receptor kinase in complex2 with the sh2 domain of aps
72 c2ci8A_
not modelled
99.0
23
PDB header: translationChain: A: PDB Molecule: cytoplasmic protein nck1;
PDBTitle: sh2 domain of human nck1 adaptor protein - uncomplexed
73 c1a81E_
not modelled
99.0
23
PDB header: complex (transferase/peptide)Chain: E: PDB Molecule: syk kinase;
PDBTitle: crystal structure of the tandem sh2 domain of the syk kinase bound to2 a dually tyrosine-phosphorylated itam
74 d2shpa2
not modelled
99.0
28
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
75 d3c7ia1
not modelled
98.9
20
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
76 c2dvjA_
not modelled
98.9
31
PDB header: signaling proteinChain: A: PDB Molecule: v-crk sarcoma virus ct10 oncogene homolog,
PDBTitle: phosphorylated crk-ii
77 d1ayaa_
not modelled
98.9
29
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
78 d1blja_
not modelled
98.9
25
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
79 d2shpa3
not modelled
98.9
27
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
80 d1i3za_
not modelled
98.9
24
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
81 c2eobA_
not modelled
98.9
20
PDB header: hydrolaseChain: A: PDB Molecule: 1-phosphatidylinositol-4,5-bisphosphate
PDBTitle: solution structure of the second sh2 domain from rat plc2 gamma-2
82 c2augB_
not modelled
98.9
25
PDB header: signaling proteinChain: B: PDB Molecule: growth factor receptor-bound protein 14;
PDBTitle: crystal structure of the grb14 sh2 domain
83 c2eyzA_
not modelled
98.9
31
PDB header: signaling proteinChain: A: PDB Molecule: v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform ii
84 d1lkka_
not modelled
98.9
26
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
85 d1pica_
not modelled
98.9
23
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
86 d1d4ta_
not modelled
98.9
22
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
87 d2qmsa1
not modelled
98.9
24
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
88 d1qcfa2
not modelled
98.9
22
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
89 c3pfqA_
not modelled
98.9
37
PDB header: transferaseChain: A: PDB Molecule: protein kinase c beta type;
PDBTitle: crystal structure and allosteric activation of protein kinase c beta2 ii
90 d1f2fa_
not modelled
98.9
26
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
91 c1y57A_
not modelled
98.9
30
PDB header: transferaseChain: A: PDB Molecule: proto-oncogene tyrosine-protein kinase src;
PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor
92 c2knoA_
not modelled
98.8
22
PDB header: hydrolaseChain: A: PDB Molecule: tensin-like c1 domain-containing phosphatase;
PDBTitle: nmr solution structure of sh2 domain of the human tensin like c12 domain containing phosphatase (tenc1)
93 d1fu6a_
not modelled
98.8
24
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
94 d1cwea_
not modelled
98.8
28
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
95 c3mazA_
not modelled
98.8
15
PDB header: signaling proteinChain: A: PDB Molecule: signal-transducing adaptor protein 1;
PDBTitle: crystal structure of the human brdg1/stap-1 sh2 domain in complex with2 the ntal ptyr136 peptide
96 d1qada_
not modelled
98.8
25
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
97 d1g83a2
not modelled
98.8
29
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
98 c1x27F_
not modelled
98.8
20
PDB header: signaling proteinChain: F: PDB Molecule: proto-oncogene tyrosine-protein kinase lck;
PDBTitle: crystal structure of lck sh2-sh3 with sh2 binding site of2 p130cas
99 d1bkla_
not modelled
98.8
30
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
100 d1mila_
not modelled
98.8
30
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
101 c2kk6A_
not modelled
98.8
24
PDB header: transferaseChain: A: PDB Molecule: proto-oncogene tyrosine-protein kinase fer;
PDBTitle: solution structure of sh2 domain of proto-oncogene tyrosine-2 protein kinase fer from homo sapiens, northeast structural3 genomics consortium (nesg) target hr3461d
102 d1o48a_
not modelled
98.8
30
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
103 c2dcrA_
not modelled
98.8
21
PDB header: transferaseChain: A: PDB Molecule: proto-oncogene tyrosine-protein kinase fes/fps;
PDBTitle: fully automated solution structure determination of the fes2 sh2 domain
104 c2h8hA_
not modelled
98.8
30
PDB header: transferaseChain: A: PDB Molecule: proto-oncogene tyrosine-protein kinase src;
PDBTitle: src kinase in complex with a quinazoline inhibitor
105 d1luia_
not modelled
98.8
25
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
106 d1xa6a3
not modelled
98.7
63
Fold: Cysteine-rich domainSuperfamily: Cysteine-rich domainFamily: Protein kinase cysteine-rich domain (cys2, phorbol-binding domain)
107 c3nhnA_
not modelled
98.7
22
PDB header: transferaseChain: A: PDB Molecule: tyrosine-protein kinase hck;
PDBTitle: crystal structure of the src-family kinase hck sh3-sh2-linker2 regulatory region
108 c2ekxA_
not modelled
98.7
21
PDB header: signaling proteinChain: A: PDB Molecule: cytoplasmic tyrosine-protein kinase bmx;
PDBTitle: solution structure of the human bmx sh2 domain
109 c2cr4A_
not modelled
98.7
17
PDB header: signaling proteinChain: A: PDB Molecule: sh3 domain-binding protein 2;
PDBTitle: solution structure of the sh2 domain of human sh3bp2 protein
110 c3gxxB_
not modelled
98.7
18
PDB header: transcriptionChain: B: PDB Molecule: transcription elongation factor spt6;
PDBTitle: structure of the sh2 domain of the candida glabrata2 transcription elongation factor spt6, crystal form b
111 c2eliA_
not modelled
98.7
29
PDB header: transferaseChain: A: PDB Molecule: protein kinase c alpha type;
PDBTitle: solution structure of the second phorbol2 esters/diacylglycerol binding domain of human protein3 kinase c alpha type
112 c2c0iA_
not modelled
98.7
28
PDB header: transferaseChain: A: PDB Molecule: tyrosine-protein kinase hck;
PDBTitle: src family kinase hck with bound inhibitor a-420983
113 c2eyyA_
not modelled
98.7
31
PDB header: signaling proteinChain: A: PDB Molecule: v-crk sarcoma virus ct10 oncogene homolog
PDBTitle: ct10-regulated kinase isoform i
114 c2ge9A_
not modelled
98.7
24
PDB header: transferaseChain: A: PDB Molecule: tyrosine-protein kinase btk;
PDBTitle: solution structures of the sh2 domain of bruton's tyrosine2 kinase
115 c2dm0A_
not modelled
98.7
18
PDB header: transferaseChain: A: PDB Molecule: tyrosine-protein kinase txk;
PDBTitle: solution structure of the sh2 domain of human tyrosine-2 protein kinase txk
116 c4b6dA_
not modelled
98.6
29
PDB header: signaling proteinChain: A: PDB Molecule: rac gtpase-activating protein 1;
PDBTitle: structure of the atypical c1 domain of mgcracgap
117 d2fcia1
not modelled
98.6
22
Fold: SH2-likeSuperfamily: SH2 domainFamily: SH2 domain
118 c2e73A_
not modelled
98.6
32
PDB header: transferaseChain: A: PDB Molecule: protein kinase c gamma type;
PDBTitle: solution structure of the phorbol esters/diacylglycerol2 binding domain of protein kinase c gamma
119 d1tbna_
not modelled
98.6
29
Fold: Cysteine-rich domainSuperfamily: Cysteine-rich domainFamily: Protein kinase cysteine-rich domain (cys2, phorbol-binding domain)
120 c1g83A_
not modelled
98.6
26
PDB header: transferaseChain: A: PDB Molecule: proto-oncogene tyrosine-protein kinase fyn;
PDBTitle: crystal structure of fyn sh3-sh2