Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP37650
DateWed Jan 25 15:20:52 GMT 2012
Unique Job IDefe91011ff89f79b

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c2xpiA_
Top template information
PDB header:cell cycle
Chain: A: PDB Molecule:anaphase-promoting complex subunit cut9;
PDBTitle: crystal structure of apc/c hetero-tetramer cut9-hcn1
Confidence and coverage
Confidence:100.0% Coverage: 43%
498 residues ( 43% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
878 residues ( 76%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MRKFTLNIFTLSLGLAVMPMVEAAPTAQQQLLEQVRLGEATHREDLVQQSLYRLELIDPN
Secondary structure 
SS confidence 
Disorder  ????
??
???
Disorder confidence 
 
   .........70.........80.........90.........100.........110.........120
Sequence  NPDVVAARFRSLLRQGDIDGAQKQLDRLSQLAPSSNAYKSSRTTMLLSTPDGRQALQQAR
Secondary structure 
SS confidence 
Disorder 
?
Disorder confidence 
 
   .........130.........140.........150.........160.........170.........180
Sequence  LQATTGHAEEAVASYNKLFNGAPPEGDIAVEYWSTVAKIPARRGEAINQLKRINADAPGN
Secondary structure 
SS confidence 
Disorder 
???
??
Disorder confidence 
 
   .........190.........200.........210.........220.........230.........240
Sequence  TGLQNNLALLLFSSDRRDEGFAVLEQMAKSNAGREGASKIWYGQIKDMPVSDASVSALKK
Secondary structure 
SS confidence 
Disorder 
??
Disorder confidence 
 
   .........250.........260.........270.........280.........290.........300
Sequence  YLSIFSDGDSVAAAQSQLAEQQKQLADPAFRARAQGLAAVDSGMAGKAIPELQQAVRANP
Secondary structure 
SS confidence 
Disorder 
????
?
Disorder confidence 
 
   .........310.........320.........330.........340.........350.........360
Sequence  KDSEALGALGQAYSQKGDRANAVANLEKALALDPHSSNNDKWNSLLKVNRYWLAIQQGDA
Secondary structure 
SS confidence 
Disorder 
??
Disorder confidence 
 
   .........370.........380.........390.........400.........410.........420
Sequence  ALKANNPDRAERLFQQARNVDNTDSYAVLGLGDVAMARKDYPAAERYYQQTLRMDSGNTN
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........430.........440.........450.........460.........470.........480
Sequence  AVRGLANIYRQQSPEKAEAFIASLSASQRRSIDDIERSLQNDRLAQQAEALENQGKWAQA
Secondary structure 
SS confidence 
Disorder 
???????
??
Disorder confidence 
 
   .........490.........500.........510.........520.........530.........540
Sequence  AALQRQRLALDPGSVWITYRLSQDLWQAGQRSQADTLMRNLAQQKSNDPEQVYAYGLYLS
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........550.........560.........570.........580.........590.........600
Sequence  GHDQDRAALAHINSLPRAQWNSNIQELVNRLQSDQVLETANRLRESGKEAEAEAMLRQQP
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........610.........620.........630.........640.........650.........660
Sequence  PSTRIDLTLADWAQQRRDYTAARAAYQNVLTREPANADAILGLTEVDIAAGDKAAARSQL
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........670.........680.........690.........700.........710.........720
Sequence  AKLPATDNASLNTQRRVALAQAQLGDTAAAQRTFNKLIPQAKSQPPSMESAMVLRDGAKF
Secondary structure 
SS confidence 
Disorder 
?
Disorder confidence 
 
   .........730.........740.........750.........760.........770.........780
Sequence  EAQAGDPTQALETYKDAMVASGVTTTRPQDNDTFTRLTRNDEKDDWLKRGVRSDAADLYR
Secondary structure 
SS confidence 
Disorder 
??
?
??
Disorder confidence 
 
   .........790.........800.........810.........820.........830.........840
Sequence  QQDLNVTLEHDYWGSSGTGGYSDLKAHTTMLQVDAPYSDGRMFFRSDFVNMNVGSFSTNA
Secondary structure 
SS confidence 
Disorder 
?
?????
??
??????
Disorder confidence 
 
   .........850.........860.........870.........880.........890.........900
Sequence  DGKWDDNWGTCTLQDCSGNRSQSDSGASVAVGWRNDVWSWDIGTTPMGFNVVDVVGGISY
Secondary structure 
SS confidence 
Disorder  ????
?
?
?????????????
??
Disorder confidence 
 
   .........910.........920.........930.........940.........950.........960
Sequence  SDDIGPLGYTVNAHRRPISSSLLAFGGQKDSPSNTGKKWGGVRADGVGLSLSYDKGEANG
Secondary structure 
SS confidence 
Disorder 
??
?
??
??????
???
???
Disorder confidence 
 
   .........970.........980.........990.........1000.........1010.........1020
Sequence  VWASLSGDQLTGKNVEDNWRVRWMTGYYYKVINQNNRRVTIGLNNMIWHYDKDLSGYSLG
Secondary structure 
SS confidence 
Disorder 
?
?
Disorder confidence 
 
   .........1030.........1040.........1050.........1060.........1070.........1080
Sequence  QGGYYSPQEYLSFAIPVMWRERTENWSWELGASGSWSHSRTKTMPRYPLMNLIPTDWQEE
Secondary structure 
SS confidence 
Disorder 
?
??
?
??
??
Disorder confidence 
 
   .........1090.........1100.........1110.........1120.........1130.........1140
Sequence  AARQSNDGGSSQGFGYTARALLERRVTSNWFVGTAIDIQQAKDYAPSHFLLYVRYSAAGW
Secondary structure 
SS confidence 
Disorder  ??????????????
?
?
Disorder confidence 
 
   .........1150.......
Sequence  QGDMDLPPQPLIPYADW
Secondary structure 
SS confidence 
Disorder 
??
?????
Disorder confidence 
 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 2xpi chain A

3D model

Region: 26 - 681
Aligned: 498
Modelled: 499
Confidence: 100.0%
Identity: 16%
PDB header:cell cycle
Chain: A: PDB Molecule:anaphase-promoting complex subunit cut9;
PDBTitle: crystal structure of apc/c hetero-tetramer cut9-hcn1

Phyre2

PDB 1w3b chain A

3D model

Region: 31 - 686
Aligned: 387
Modelled: 388
Confidence: 100.0%
Identity: 17%
Fold: alpha-alpha superhelix
Superfamily: TPR-like
Family: Tetratricopeptide repeat (TPR)

Phyre2

PDB 2ooe chain A domain 1

3D model

Region: 136 - 765
Aligned: 511
Modelled: 515
Confidence: 99.9%
Identity: 9%
Fold: alpha-alpha superhelix
Superfamily: TPR-like
Family: HAT/Suf repeat

Phyre2

PDB 3fp4 chain A

3D model

Region: 132 - 683
Aligned: 472
Modelled: 481
Confidence: 99.8%
Identity: 13%
PDB header:transport protein
Chain: A: PDB Molecule:tpr repeat-containing protein yhr117w;
PDBTitle: crystal structure of tom71 complexed with ssa1 c-terminal2 fragment

Phyre2

PDB 2gw1 chain A

3D model

Region: 112 - 736
Aligned: 472
Modelled: 482
Confidence: 99.8%
Identity: 11%
PDB header:protein transport
Chain: A: PDB Molecule:mitochondrial precursor proteins import receptor;
PDBTitle: crystal structure of the yeast tom70

Phyre2

PDB 2y4t chain A

3D model

Region: 26 - 518
Aligned: 400
Modelled: 410
Confidence: 99.8%
Identity: 17%
PDB header:chaperone
Chain: A: PDB Molecule:dnaj homolog subfamily c member 3;
PDBTitle: crystal structure of the human co-chaperone p58(ipk)

Phyre2

PDB 3ieg chain B

3D model

Region: 26 - 433
Aligned: 340
Modelled: 350
Confidence: 99.8%
Identity: 19%
PDB header:chaperone
Chain: B: PDB Molecule:dnaj homolog subfamily c member 3;
PDBTitle: crystal structure of p58(ipk) tpr domain at 2.5 a

Phyre2

PDB 1qsa chain A domain 1

3D model

Region: 113 - 668
Aligned: 438
Modelled: 472
Confidence: 99.7%
Identity: 13%
Fold: alpha-alpha superhelix
Superfamily: Bacterial muramidases
Family: Bacterial muramidases

Phyre2

PDB 1fch chain B

3D model

Region: 464 - 749
Aligned: 281
Modelled: 286
Confidence: 99.7%
Identity: 12%
PDB header:signaling protein
Chain: B: PDB Molecule:peroxisomal targeting signal 1 receptor;
PDBTitle: crystal structure of the pts1 complexed to the tpr region2 of human pex5

Phyre2

PDB 3pe3 chain D

3D model

Region: 25 - 209
Aligned: 168
Modelled: 169
Confidence: 99.7%
Identity: 14%
PDB header:transferase
Chain: D: PDB Molecule:udp-n-acetylglucosamine--peptide n-
PDBTitle: structure of human o-glcnac transferase and its complex with a peptide2 substrate

Phyre2

PDB 1fch chain A

3D model

Region: 464 - 749
Aligned: 281
Modelled: 286
Confidence: 99.7%
Identity: 11%
Fold: alpha-alpha superhelix
Superfamily: TPR-like
Family: Tetratricopeptide repeat (TPR)

Phyre2

PDB 2ho1 chain B

3D model

Region: 25 - 256
Aligned: 216
Modelled: 216
Confidence: 99.7%
Identity: 13%
PDB header:protein binding
Chain: B: PDB Molecule:type 4 fimbrial biogenesis protein pilf;
PDBTitle: functional characterization of pseudomonas aeruginosa pilf

Phyre2

PDB 3hym chain B

3D model

Region: 26 - 344
Aligned: 292
Modelled: 303
Confidence: 99.7%
Identity: 12%
PDB header:cell cycle, ligase
Chain: B: PDB Molecule:cell division cycle protein 16 homolog;
PDBTitle: insights into anaphase promoting complex tpr subdomain2 assembly from a cdc26-apc6 structure

Phyre2

PDB 3cvp chain A

3D model

Region: 464 - 742
Aligned: 260
Modelled: 279
Confidence: 99.7%
Identity: 13%
PDB header:transport protein
Chain: A: PDB Molecule:peroxisome targeting signal 1 receptor pex5;
PDBTitle: structure of peroxisomal targeting signal 1 (pts1) binding2 domain of trypanosoma brucei peroxin 5 (tbpex5)complexed3 to pts1 peptide (10-skl)

Phyre2

PDB 2uy1 chain A

3D model

Region: 301 - 740
Aligned: 376
Modelled: 397
Confidence: 99.6%
Identity: 12%
PDB header:rna-binding protein
Chain: A: PDB Molecule:cleavage stimulation factor 77;
PDBTitle: crystal structure of cstf-77

Phyre2

PDB 2vq2 chain A

3D model

Region: 24 - 255
Aligned: 217
Modelled: 217
Confidence: 99.6%
Identity: 14%
PDB header:structural protein
Chain: A: PDB Molecule:putative fimbrial biogenesis and twitching
PDBTitle: crystal structure of pilw, widely conserved type iv pilus2 biogenesis factor

Phyre2

PDB 1hz4 chain A

3D model

Region: 457 - 742
Aligned: 286
Modelled: 286
Confidence: 99.6%
Identity: 17%
Fold: alpha-alpha superhelix
Superfamily: TPR-like
Family: Transcription factor MalT domain III

Phyre2

PDB 3dra chain A

3D model

Region: 18 - 334
Aligned: 258
Modelled: 267
Confidence: 99.6%
Identity: 11%
PDB header:transferase
Chain: A: PDB Molecule:protein
PDBTitle: candida albicans protein geranylgeranyltransferase-i2 complexed with ggpp

Phyre2

PDB 1xi4 chain D

3D model

Region: 35 - 703
Aligned: 592
Modelled: 592
Confidence: 99.5%
Identity: 12%
PDB header:endocytosis/exocytosis
Chain: D: PDB Molecule:clathrin heavy chain;
PDBTitle: clathrin d6 coat

Phyre2

PDB 2q7f chain A

3D model

Region: 47 - 256
Aligned: 193
Modelled: 194
Confidence: 99.5%
Identity: 13%
PDB header:protein binding
Chain: A: PDB Molecule:yrrb protein;
PDBTitle: crystal structure of yrrb: a tpr protein with an unusual peptide-2 binding site

Phyre2

PDB 2k0l chain A

3D model

Region: 960 - 1153
Aligned: 174
Modelled: 174
Confidence: 98.4%
Identity: 11%
PDB header:membrane protein
Chain: A: PDB Molecule:outer membrane protein a;
PDBTitle: nmr structure of the transmembrane domain of the outer2 membrane protein a from klebsiella pneumoniae in dhpc3 micelles.

Phyre2

PDB 2f1t chain B

3D model

Region: 957 - 1138
Aligned: 162
Modelled: 162
Confidence: 97.9%
Identity: 12%
PDB header:membrane protein
Chain: B: PDB Molecule:outer membrane protein w;
PDBTitle: outer membrane protein ompw

Phyre2

PDB 2x27 chain X

3D model

Region: 945 - 1138
Aligned: 178
Modelled: 178
Confidence: 97.8%
Identity: 11%
PDB header:membrane protein
Chain: X: PDB Molecule:outer membrane protein oprg;
PDBTitle: crystal structure of the outer membrane protein oprg from2 pseudomonas aeruginosa

Phyre2

PDB 2x4m chain D

3D model

Region: 902 - 1139
Aligned: 217
Modelled: 217
Confidence: 97.3%
Identity: 17%
PDB header:hydrolase
Chain: D: PDB Molecule:coagulase/fibrinolysin;
PDBTitle: yersinia pestis plasminogen activator pla

Phyre2

PDB 1i78 chain A

3D model

Region: 871 - 1120
Aligned: 226
Modelled: 226
Confidence: 97.3%
Identity: 16%
Fold: Transmembrane beta-barrels
Superfamily: OMPT-like
Family: Outer membrane protease OMPT

Phyre2

PDB 1by5 chain A

3D model

Region: 821 - 1052
Aligned: 222
Modelled: 222
Confidence: 88.6%
Identity: 13%
Fold: Transmembrane beta-barrels
Superfamily: Porins
Family: Ligand-gated protein channel

Phyre2
1
c2xpiA_
2
d1w3ba_
3
d2ooea1
4
c3fp4A_
5
c2gw1A_
6
c2y4tA_
7
c3iegB_
8
d1qsaa1
9
c1fchB_
10
c3pe3D_
11
d1fcha_
12
c2ho1B_
13
c3hymB_
14
c3cvpA_
15
c2uy1A_
16
c2vq2A_
17
d1hz4a_
18
c3draA_
19
c1xi4D_
20
c2q7fA_
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24
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c2k0lA_
85
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c2f1tB_
100
101
c2x27X_
102
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c2x4mD_
105
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d1i78a_
107
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d1by5a_
140
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c2xpiA_
100.0 16 PDB header:cell cycle
Chain: A: PDB Molecule:anaphase-promoting complex subunit cut9;
PDBTitle: crystal structure of apc/c hetero-tetramer cut9-hcn1
2d1w3ba_
100.0 17 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
3d2ooea1
99.9 9 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:HAT/Suf repeat
4c3fp4A_
99.8 13 PDB header:transport protein
Chain: A: PDB Molecule:tpr repeat-containing protein yhr117w;
PDBTitle: crystal structure of tom71 complexed with ssa1 c-terminal2 fragment
5c2gw1A_
99.8 11 PDB header:protein transport
Chain: A: PDB Molecule:mitochondrial precursor proteins import receptor;
PDBTitle: crystal structure of the yeast tom70
6c2y4tA_
99.8 17 PDB header:chaperone
Chain: A: PDB Molecule:dnaj homolog subfamily c member 3;
PDBTitle: crystal structure of the human co-chaperone p58(ipk)
7c3iegB_
99.8 19 PDB header:chaperone
Chain: B: PDB Molecule:dnaj homolog subfamily c member 3;
PDBTitle: crystal structure of p58(ipk) tpr domain at 2.5 a
8d1qsaa1
99.7 13 Fold:alpha-alpha superhelix
Superfamily:Bacterial muramidases
Family:Bacterial muramidases
9c1fchB_
99.7 12 PDB header:signaling protein
Chain: B: PDB Molecule:peroxisomal targeting signal 1 receptor;
PDBTitle: crystal structure of the pts1 complexed to the tpr region2 of human pex5
10c3pe3D_
99.7 14 PDB header:transferase
Chain: D: PDB Molecule:udp-n-acetylglucosamine--peptide n-
PDBTitle: structure of human o-glcnac transferase and its complex with a peptide2 substrate
11d1fcha_
99.7 11 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
12c2ho1B_
99.7 13 PDB header:protein binding
Chain: B: PDB Molecule:type 4 fimbrial biogenesis protein pilf;
PDBTitle: functional characterization of pseudomonas aeruginosa pilf
13c3hymB_
99.7 12 PDB header:cell cycle, ligase
Chain: B: PDB Molecule:cell division cycle protein 16 homolog;
PDBTitle: insights into anaphase promoting complex tpr subdomain2 assembly from a cdc26-apc6 structure
14c3cvpA_
99.7 13 PDB header:transport protein
Chain: A: PDB Molecule:peroxisome targeting signal 1 receptor pex5;
PDBTitle: structure of peroxisomal targeting signal 1 (pts1) binding2 domain of trypanosoma brucei peroxin 5 (tbpex5)complexed3 to pts1 peptide (10-skl)
15c2uy1A_
99.6 12 PDB header:rna-binding protein
Chain: A: PDB Molecule:cleavage stimulation factor 77;
PDBTitle: crystal structure of cstf-77
16c2vq2A_
99.6 14 PDB header:structural protein
Chain: A: PDB Molecule:putative fimbrial biogenesis and twitching
PDBTitle: crystal structure of pilw, widely conserved type iv pilus2 biogenesis factor
17d1hz4a_
99.6 17 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Transcription factor MalT domain III
18c3draA_
99.6 11 PDB header:transferase
Chain: A: PDB Molecule:protein
PDBTitle: candida albicans protein geranylgeranyltransferase-i2 complexed with ggpp
19c1xi4D_
99.5 12 PDB header:endocytosis/exocytosis
Chain: D: PDB Molecule:clathrin heavy chain;
PDBTitle: clathrin d6 coat
20c2q7fA_
99.5 13 PDB header:protein binding
Chain: A: PDB Molecule:yrrb protein;
PDBTitle: crystal structure of yrrb: a tpr protein with an unusual peptide-2 binding site
21d2h6fa1
not modelled 99.5 11 Fold:alpha-alpha superhelix
Superfamily:Protein prenylyltransferase
Family:Protein prenylyltransferase
22d1d8da_
not modelled 99.5 11 Fold:alpha-alpha superhelix
Superfamily:Protein prenylyltransferase
Family:Protein prenylyltransferase
23c3q75A_
not modelled 99.5 11 PDB header:transferase
Chain: A: PDB Molecule:farnesyltransferase alpha subunit;
PDBTitle: cryptococcus neoformans protein farnesyltransferase in complex with2 fpt-ii and tkcvvm peptide
24d1dcea1
not modelled 99.5 10 Fold:alpha-alpha superhelix
Superfamily:Protein prenylyltransferase
Family:Protein prenylyltransferase
25d1xnfa_
not modelled 99.5 13 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
26c3mkrA_
not modelled 99.5 14 PDB header:transport protein
Chain: A: PDB Molecule:coatomer subunit epsilon;
PDBTitle: crystal structure of yeast alpha/epsilon-cop subcomplex of the copi2 vesicular coat
27c1tnoI_
not modelled 99.5 11 PDB header:transferase
Chain: I: PDB Molecule:geranylgeranyltransferase type i alpha subunit;
PDBTitle: rat protein geranylgeranyltransferase type-i complexed with2 a ggpp analog and a kkksktkcvim peptide derived from k-3 ras4b
28c3urzB_
not modelled 99.5 11 PDB header:protein binding
Chain: B: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of a hypothetical protein (bacova_03105) from2 bacteroides ovatus atcc 8483 at 2.19 a resolution
29c2r5sB_
not modelled 99.4 16 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:uncharacterized protein vp0806;
PDBTitle: the crystal structure of a domain of protein vp0806 (unknown function)2 from vibrio parahaemolyticus rimd 2210633
30c3mv3B_
not modelled 99.4 15 PDB header:protein transport
Chain: B: PDB Molecule:coatomer subunit epsilon;
PDBTitle: crystal structure of a-cop in complex with e-cop
31c2pl2A_
not modelled 99.4 18 PDB header:protein binding
Chain: A: PDB Molecule:hypothetical conserved protein ttc0263;
PDBTitle: crystal structure of ttc0263: a thermophilic tpr protein in thermus2 thermophilus hb27
32c3as5A_
not modelled 99.4 15 PDB header:protein binding
Chain: A: PDB Molecule:mama;
PDBTitle: mama amb-1 p212121
33c1slyA_
not modelled 99.3 13 PDB header:glycosyltransferase
Chain: A: PDB Molecule:70-kda soluble lytic transglycosylase;
PDBTitle: complex of the 70-kda soluble lytic transglycosylase with2 bulgecin a
34c3qdnA_
not modelled 99.3 9 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative thioredoxin protein;
PDBTitle: putative thioredoxin protein from salmonella typhimurium
35d2onda1
not modelled 99.3 9 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:HAT/Suf repeat
36c2e2eA_
not modelled 99.1 17 PDB header:lyase
Chain: A: PDB Molecule:formate-dependent nitrite reductase complex nrfg subunit;
PDBTitle: tpr domain of nrfg mediates the complex formation between heme lyase2 and formate-dependent nitrite reductase in escherichia coli o157:h7
37c2hyzA_
not modelled 99.1 22 PDB header:de novo protein
Chain: A: PDB Molecule:synthetic consensus tpr protein;
PDBTitle: crystal structure of an 8 repeat consensus tpr superhelix2 (orthorombic crystal form)
38c3ulqA_
not modelled 99.1 10 PDB header:gene regulation/transcription activator
Chain: A: PDB Molecule:response regulator aspartate phosphatase f;
PDBTitle: crystal structure of the anti-activator rapf complexed with the2 response regulator coma dna binding domain
39c3q15A_
not modelled 99.1 9 PDB header:hydrolase/kinase
Chain: A: PDB Molecule:response regulator aspartate phosphatase h;
PDBTitle: crystal structure of raph complexed with spo0f
40c3ly8A_
not modelled 99.1 13 PDB header:signaling protein
Chain: A: PDB Molecule:transcriptional activator cadc;
PDBTitle: crystal structure of mutant d471e of the periplasmic domain of cadc
41c2yhcA_
not modelled 99.1 11 PDB header:membrane protein
Chain: A: PDB Molecule:upf0169 lipoprotein yfio;
PDBTitle: structure of bamd from e. coli
42d1hh8a_
not modelled 99.1 12 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
43c3gw4B_
not modelled 99.0 19 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of uncharacterized protein from deinococcus2 radiodurans. northeast structural genomics consortium target drr162b.
44c2xcbA_
not modelled 99.0 18 PDB header:protein binding
Chain: A: PDB Molecule:regulatory protein pcrh;
PDBTitle: crystal structure of pcrh in complex with the chaperone2 binding region of popd
45c1wao4_
not modelled 99.0 16 PDB header:hydrolase
Chain: 4: PDB Molecule:serine/threonine protein phosphatase 5;
PDBTitle: pp5 structure
46c3sf4B_
not modelled 99.0 13 PDB header:signaling protein/protein binding
Chain: B: PDB Molecule:g-protein-signaling modulator 2;
PDBTitle: crystal structure of the complex between the conserved cell polarity2 proteins inscuteable and lgn
47c3gyzB_
not modelled 99.0 13 PDB header:chaperone
Chain: B: PDB Molecule:chaperone protein ipgc;
PDBTitle: crystal structure of ipgc from shigella flexneri
48d2c2la1
not modelled 99.0 16 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
49c3qkyA_
not modelled 99.0 13 PDB header:membrane protein
Chain: A: PDB Molecule:outer membrane assembly lipoprotein yfio;
PDBTitle: crystal structure of rhodothermus marinus bamd
50c2c2lD_
not modelled 99.0 18 PDB header:chaperone
Chain: D: PDB Molecule:carboxy terminus of hsp70-interacting protein;
PDBTitle: crystal structure of the chip u-box e3 ubiquitin ligase
51c2vsnB_
not modelled 98.9 13 PDB header:transferase
Chain: B: PDB Molecule:xcogt;
PDBTitle: structure and topological arrangement of an o-glcnac2 transferase homolog: insight into molecular control of3 intracellular glycosylation
52d1elwa_
not modelled 98.9 17 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
53d1hxia_
not modelled 98.9 14 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
54c2ifuA_
not modelled 98.9 14 PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:gamma-snap;
PDBTitle: crystal structure of a gamma-snap from danio rerio
55d1a17a_
not modelled 98.9 15 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
56c2vyiA_
not modelled 98.9 17 PDB header:chaperone
Chain: A: PDB Molecule:sgta protein;
PDBTitle: crystal structure of the tpr domain of human sgt
57d1zbpa1
not modelled 98.8 12 Fold:ImpE-like
Superfamily:ImpE-like
Family:ImpE-like
58c3q49B_
not modelled 98.8 18 PDB header:ligase/chaperone
Chain: B: PDB Molecule:stip1 homology and u box-containing protein 1;
PDBTitle: crystal structure of the tpr domain of chip complexed with hsp70-c2 peptide
59d1zu2a1
not modelled 98.8 15 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
60c3sz7A_
not modelled 98.8 19 PDB header:chaperone regulator
Chain: A: PDB Molecule:hsc70 cochaperone (sgt);
PDBTitle: crystal structure of the sgt2 tpr domain from aspergillus fumigatus
61c2kckA_
not modelled 98.8 8 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:tpr repeat;
PDBTitle: nmr solution structure of the northeast structural genomics2 consortium (nesg) target mrr121a
62c2xevB_
not modelled 98.7 14 PDB header:metal binding
Chain: B: PDB Molecule:ybgf;
PDBTitle: crystal structure of the tpr domain of xanthomonas2 campestris ybgf
63c2katA_
not modelled 98.7 15 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: solution structure of protein bpp2914 from bordetella2 parapertussis. northeast structural genomics consortium3 target bpr206
64d2buga1
not modelled 98.7 16 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
65c2dbaA_
not modelled 98.7 15 PDB header:structural protein
Chain: A: PDB Molecule:smooth muscle cell associated protein-1, isoform
PDBTitle: the solution structure of the tetratrico peptide repeat of2 human smooth muscle cell associated protein-1, isoform 2
66d1qqea_
not modelled 98.7 10 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
67c1ltxA_
not modelled 98.6 9 PDB header:transferase/protein binding
Chain: A: PDB Molecule:rab geranylgeranyltransferase alpha subunit;
PDBTitle: structure of rab escort protein-1 in complex with rab2 geranylgeranyl transferase and isoprenoid
68c1na3A_
not modelled 98.6 24 PDB header:de novo protein
Chain: A: PDB Molecule:designed protein ctpr2;
PDBTitle: design of stable alpha-helical arrays from an idealized tpr2 motif
69d1kt1a1
not modelled 98.6 16 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
70c2vgxA_
not modelled 98.6 11 PDB header:chaperone
Chain: A: PDB Molecule:chaperone sycd;
PDBTitle: structure of the yersinia enterocolitica type iii secretion2 translocator chaperone sycd
71d1ihga1
not modelled 98.5 14 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
72d1p5qa1
not modelled 98.5 15 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
73d1elra_
not modelled 98.5 12 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
74c3k9iA_
not modelled 98.5 17 PDB header:protein binding
Chain: A: PDB Molecule:bh0479 protein;
PDBTitle: crystal structure of putative protein binding protein (np_241345.1)2 from bacillus halodurans at 2.71 a resolution
75c3rkvA_
not modelled 98.5 18 PDB header:isomerase
Chain: A: PDB Molecule:putative peptidylprolyl isomerase;
PDBTitle: c-terminal domain of protein c56c10.10, a putative peptidylprolyl2 isomerase, from caenorhabditis elegans
76c1ihgA_
not modelled 98.5 13 PDB header:isomerase
Chain: A: PDB Molecule:cyclophilin 40;
PDBTitle: bovine cyclophilin 40, monoclinic form
77d2fbna1
not modelled 98.5 10 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
78c2fbnA_
not modelled 98.5 10 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:70 kda peptidylprolyl isomerase, putative;
PDBTitle: plasmodium falciparum putative fk506-binding protein2 pfl2275c, c-terminal tpr-containing domain
79c2kc7A_
not modelled 98.5 16 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:bfr218_protein;
PDBTitle: solution nmr structure of bacteroides fragilis protein2 bf1650. northeast structural genomics consortium target3 bfr218
80c1kt0A_
not modelled 98.5 17 PDB header:isomerase
Chain: A: PDB Molecule:51 kda fk506-binding protein;
PDBTitle: structure of the large fkbp-like protein, fkbp51, involved in steroid2 receptor complexes
81d2hr2a1
not modelled 98.4 20 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:CT2138-like
82c2kcvA_
not modelled 98.4 11 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:tetratricopeptide repeat domain protein;
PDBTitle: solution nmr structure of tetratricopeptide repeat domain2 protein sru_0103 from salinibacter ruber, northeast3 structural genomics consortium (nesg) target srr115c
83d1iyga_
not modelled 98.4 7 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
84c2k0lA_
98.4 11 PDB header:membrane protein
Chain: A: PDB Molecule:outer membrane protein a;
PDBTitle: nmr structure of the transmembrane domain of the outer2 membrane protein a from klebsiella pneumoniae in dhpc3 micelles.
85c1qz2B_
not modelled 98.4 17 PDB header:isomerase/chaperone
Chain: B: PDB Molecule:fk506-binding protein 4;
PDBTitle: crystal structure of fkbp52 c-terminal domain complex with2 the c-terminal peptide meevd of hsp90
86d1nzna_
not modelled 98.4 9 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
87c2l6jA_
not modelled 98.4 16 PDB header:protein binding
Chain: A: PDB Molecule:tpr repeat-containing protein associated with hsp90;
PDBTitle: tah1 complexed by meevd
88c2avpA_
not modelled 98.4 16 PDB header:de novo protein
Chain: A: PDB Molecule:synthetic consensus tpr protein;
PDBTitle: crystal structure of an 8 repeat consensus tpr superhelix
89d1pc2a_
not modelled 98.3 13 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
90c3ceqB_
not modelled 98.3 12 PDB header:motor protein, transport protein
Chain: B: PDB Molecule:kinesin light chain 2;
PDBTitle: the tpr domain of human kinesin light chain 2 (hklc2)
91c3nf1A_
not modelled 98.3 10 PDB header:motor protein, transport protein
Chain: A: PDB Molecule:kinesin light chain 1;
PDBTitle: crystal structure of the tpr domain of kinesin light chain 1
92c3beeB_
not modelled 98.3 11 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:putative yfre protein;
PDBTitle: crystal structure of putative yfre protein from vibrio2 parahaemolyticus
93c2if4A_
not modelled 98.3 13 PDB header:signaling protein
Chain: A: PDB Molecule:atfkbp42;
PDBTitle: crystal structure of a multi-domain immunophilin from2 arabidopsis thaliana
94d1tjca_
not modelled 98.2 14 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
95d2ff4a2
not modelled 98.2 14 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:BTAD-like
96c3n71A_
not modelled 98.1 12 PDB header:transcription
Chain: A: PDB Molecule:histone lysine methyltransferase smyd1;
PDBTitle: crystal structure of cardiac specific histone methyltransferase smyd1
97c3fflC_
not modelled 98.0 20 PDB header:cell cycle
Chain: C: PDB Molecule:anaphase-promoting complex subunit 7;
PDBTitle: crystal structure of the n-terminal domain of anaphase-2 promoting complex subunit 7
98d1y8ma1
not modelled 98.0 14 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
99c2f1tB_
97.9 12 PDB header:membrane protein
Chain: B: PDB Molecule:outer membrane protein w;
PDBTitle: outer membrane protein ompw
100d1p4ta_
not modelled 97.8 16 Fold:Transmembrane beta-barrels
Superfamily:OMPA-like
Family:Outer membrane protein
101c2x27X_
97.8 11 PDB header:membrane protein
Chain: X: PDB Molecule:outer membrane protein oprg;
PDBTitle: crystal structure of the outer membrane protein oprg from2 pseudomonas aeruginosa
102c2lhfA_
not modelled 97.7 14 PDB header:membrane protein
Chain: A: PDB Molecule:outer membrane protein h1;
PDBTitle: solution structure of outer membrane protein h (oprh) from p.2 aeruginosa in dhpc micelles
103d2pqrb1
not modelled 97.6 7 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
104c2x4mD_
97.3 17 PDB header:hydrolase
Chain: D: PDB Molecule:coagulase/fibrinolysin;
PDBTitle: yersinia pestis plasminogen activator pla
105c3sljA_
not modelled 97.3 13 PDB header:protein transport
Chain: A: PDB Molecule:serine protease espp;
PDBTitle: pre-cleavage structure of the autotransporter espp - n1023a mutant
106d1i78a_
97.3 16 Fold:Transmembrane beta-barrels
Superfamily:OMPT-like
Family:Outer membrane protease OMPT
107c3kvnA_
not modelled 97.3 12 PDB header:hydrolase
Chain: A: PDB Molecule:esterase esta;
PDBTitle: crystal structure of the full-length autotransporter esta from2 pseudomonas aeruginosa
108c3qraA_
not modelled 97.2 10 PDB header:cell invasion
Chain: A: PDB Molecule:attachment invasion locus protein;
PDBTitle: the crystal structure of ail, the attachment invasion locus protein of2 yersinia pestis
109d1g90a_
not modelled 97.1 15 Fold:Transmembrane beta-barrels
Superfamily:OMPA-like
Family:Outer membrane protein
110c2ff4B_
not modelled 97.1 14 PDB header:transcription
Chain: B: PDB Molecule:probable regulatory protein embr;
PDBTitle: mycobacterium tuberculosis embr in complex with low affinity2 phosphopeptide
111d1qj8a_
not modelled 97.1 15 Fold:Transmembrane beta-barrels
Superfamily:OMPA-like
Family:Outer membrane protein
112c3q3hA_
not modelled 97.1 7 PDB header:transferase
Chain: A: PDB Molecule:hmw1c-like glycosyltransferase;
PDBTitle: crystal structure of the actinobacillus pleuropneumoniae hmw1c2 glycosyltransferase in complex with udp-glc
113d1qjpa_
not modelled 97.0 11 Fold:Transmembrane beta-barrels
Superfamily:OMPA-like
Family:Outer membrane protein
114c3nb3C_
not modelled 96.9 16 PDB header:virus
Chain: C: PDB Molecule:outer membrane protein a;
PDBTitle: the host outer membrane proteins ompa and ompc are packed at specific2 sites in the shigella phage sf6 virion as structural components
115c3mekA_
not modelled 96.9 10 PDB header:transferase
Chain: A: PDB Molecule:set and mynd domain-containing protein 3;
PDBTitle: crystal structure of human histone-lysine n-2 methyltransferase smyd3 in complex with s-adenosyl-l-3 methionine
116c3mkqA_
not modelled 96.8 15 PDB header:transport protein
Chain: A: PDB Molecule:coatomer beta'-subunit;
PDBTitle: crystal structure of yeast alpha/betaprime-cop subcomplex of the copi2 vesicular coat
117c2qomB_
not modelled 96.7 11 PDB header:hydrolase
Chain: B: PDB Molecule:serine protease espp;
PDBTitle: the crystal structure of the e.coli espp autotransporter beta-domain.
118c3qwvA_
not modelled 96.7 11 PDB header:transferase
Chain: A: PDB Molecule:set and mynd domain-containing protein 2;
PDBTitle: crystal structure of histone lysine methyltransferase smyd2 in complex2 with the cofactor product adohcy
119c3aehB_
not modelled 96.6 14 PDB header:hydrolase
Chain: B: PDB Molecule:hemoglobin-binding protease hbp autotransporter;
PDBTitle: integral membrane domain of autotransporter hbp
120c3oxgA_
not modelled 96.5 13 PDB header:transferase
Chain: A: PDB Molecule:set and mynd domain-containing protein 3;
PDBTitle: human lysine methyltransferase smyd3 in complex with adohcy (form iii)

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0