Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP0AEA8
DateWed Jan 25 15:20:31 GMT 2012
Unique Job IDaadcc485f0953f8c

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c1pjtB_
Top template information
PDB header:transferase/oxidoreductase/lyase
Chain: B: PDB Molecule:siroheme synthase;
PDBTitle: the structure of the ser128ala point-mutant variant of cysg,2 the multifunctional3 methyltransferase/dehydrogenase/ferrochelatase for4 siroheme synthesis
Confidence and coverage
Confidence:100.0% Coverage:100%
455 residues (100% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MDHLPIFCQLRDRDCLIVGGGDVAERKARLLLDAGARLTVNALAFIPQFTAWADAGMLTL
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Disorder  ?????






















































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   .........70.........80.........90.........100.........110.........120
Sequence  VEGPFDESLLDTCWLAIAATDDDALNQRVSEAAEARRIFCNVVDAPKAASFIMPSIIDRS
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   .........130.........140.........150.........160.........170.........180
Sequence  PLMVAVSSGGTSPVLARLLREKLESLLPLHLGQVAKYAGQLRGRVKQQFATMGERRRFWE
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???

?







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   .........190.........200.........210.........220.........230.........240
Sequence  KLFVNDRLAQSLANNDQKAITETTEQLINEPLDHRGEVVLVGAGPGDAGLLTLKGLQQIQ
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Disorder 


??








?
?????


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   .........250.........260.........270.........280.........290.........300
Sequence  QADVVVYDRLVSDDIMNLVRRDADRVFVGKRAGYHCVPQEEINQILLREAQKGKRVVRLK
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   .........310.........320.........330.........340.........350.........360
Sequence  GGDPFIFGRGGEELETLCNAGIPFSVVPGITAASGCSAYSGIPLTHRDYAQSVRLITGHL
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   .........370.........380.........390.........400.........410.........420
Sequence  KTGGELDWENLAAEKQTLVFYMGLNQAATIQQKLIEHGMPGEMPVAIVENGTAVTQRVID
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Disorder 


??






















































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   .........430.........440.........450.......
Sequence  GTLTQLGELAQQMNSPSLIIIGRVVGLRDKLNWFSNH
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??????
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1pjt chain B

3D model

Region: 1 - 457
Aligned: 455
Modelled: 457
Confidence: 100.0%
Identity: 90%
PDB header:transferase/oxidoreductase/lyase
Chain: B: PDB Molecule:siroheme synthase;
PDBTitle: the structure of the ser128ala point-mutant variant of cysg,2 the multifunctional3 methyltransferase/dehydrogenase/ferrochelatase for4 siroheme synthesis

Phyre2

PDB 1s4d chain A

3D model

Region: 211 - 455
Aligned: 239
Modelled: 245
Confidence: 100.0%
Identity: 44%
Fold: Tetrapyrrole methylase
Superfamily: Tetrapyrrole methylase
Family: Tetrapyrrole methylase

Phyre2

PDB 1pjq chain A domain 2

3D model

Region: 216 - 457
Aligned: 233
Modelled: 242
Confidence: 100.0%
Identity: 91%
Fold: Tetrapyrrole methylase
Superfamily: Tetrapyrrole methylase
Family: Tetrapyrrole methylase

Phyre2

PDB 2ybo chain A

3D model

Region: 214 - 457
Aligned: 236
Modelled: 244
Confidence: 100.0%
Identity: 55%
PDB header:transferase
Chain: A: PDB Molecule:methyltransferase;
PDBTitle: the x-ray structure of the sam-dependent uroporphyrinogen2 iii methyltransferase nire from pseudomonas aeruginosa in3 complex with sah

Phyre2

PDB 1kyq chain C

3D model

Region: 1 - 207
Aligned: 207
Modelled: 206
Confidence: 100.0%
Identity: 21%
PDB header:oxidoreductase, lyase
Chain: C: PDB Molecule:siroheme biosynthesis protein met8;
PDBTitle: met8p: a bifunctional nad-dependent dehydrogenase and2 ferrochelatase involved in siroheme synthesis.

Phyre2

PDB 1cbf chain A

3D model

Region: 211 - 446
Aligned: 230
Modelled: 236
Confidence: 100.0%
Identity: 30%
Fold: Tetrapyrrole methylase
Superfamily: Tetrapyrrole methylase
Family: Tetrapyrrole methylase

Phyre2

PDB 1cbf chain A

3D model

Region: 211 - 446
Aligned: 230
Modelled: 236
Confidence: 100.0%
Identity: 30%
PDB header:methyltransferase
Chain: A: PDB Molecule:cobalt-precorrin-4 transmethylase;
PDBTitle: the x-ray structure of a cobalamin biosynthetic enzyme, cobalt2 precorrin-4 methyltransferase, cbif

Phyre2

PDB 3dfz chain B

3D model

Region: 4 - 202
Aligned: 196
Modelled: 199
Confidence: 100.0%
Identity: 21%
PDB header:oxidoreductase
Chain: B: PDB Molecule:precorrin-2 dehydrogenase;
PDBTitle: sirc, precorrin-2 dehydrogenase

Phyre2

PDB 1ve2 chain A domain 1

3D model

Region: 215 - 455
Aligned: 218
Modelled: 231
Confidence: 100.0%
Identity: 42%
Fold: Tetrapyrrole methylase
Superfamily: Tetrapyrrole methylase
Family: Tetrapyrrole methylase

Phyre2

PDB 3ndc chain B

3D model

Region: 217 - 449
Aligned: 222
Modelled: 233
Confidence: 100.0%
Identity: 32%
PDB header:transferase
Chain: B: PDB Molecule:precorrin-4 c(11)-methyltransferase;
PDBTitle: crystal structure of precorrin-4 c11-methyltransferase from2 rhodobacter capsulatus

Phyre2

PDB 3kwp chain A

3D model

Region: 214 - 442
Aligned: 216
Modelled: 223
Confidence: 100.0%
Identity: 19%
PDB header:transferase
Chain: A: PDB Molecule:predicted methyltransferase;
PDBTitle: crystal structure of putative methyltransferase from lactobacillus2 brevis

Phyre2

PDB 1va0 chain A domain 1

3D model

Region: 216 - 447
Aligned: 220
Modelled: 232
Confidence: 100.0%
Identity: 39%
Fold: Tetrapyrrole methylase
Superfamily: Tetrapyrrole methylase
Family: Tetrapyrrole methylase

Phyre2

PDB 2zvb chain A

3D model

Region: 216 - 456
Aligned: 232
Modelled: 241
Confidence: 100.0%
Identity: 25%
PDB header:transferase
Chain: A: PDB Molecule:precorrin-3 c17-methyltransferase;
PDBTitle: crystal structure of tt0207 from thermus thermophilus hb8

Phyre2

PDB 1wde chain A

3D model

Region: 214 - 456
Aligned: 241
Modelled: 243
Confidence: 100.0%
Identity: 18%
Fold: Tetrapyrrole methylase
Superfamily: Tetrapyrrole methylase
Family: Tetrapyrrole methylase

Phyre2

PDB 3nut chain C

3D model

Region: 215 - 444
Aligned: 219
Modelled: 230
Confidence: 100.0%
Identity: 21%
PDB header:transferase
Chain: C: PDB Molecule:precorrin-3 methylase;
PDBTitle: crystal structure of the methyltransferase cobj

Phyre2

PDB 2e0k chain A

3D model

Region: 212 - 446
Aligned: 223
Modelled: 235
Confidence: 100.0%
Identity: 20%
PDB header:transferase
Chain: A: PDB Molecule:precorrin-2 c20-methyltransferase;
PDBTitle: crystal structure of cbil, a methyltransferase involved in anaerobic2 vitamin b12 biosynthesis

Phyre2

PDB 1wyz chain A domain 1

3D model

Region: 215 - 443
Aligned: 219
Modelled: 229
Confidence: 100.0%
Identity: 14%
Fold: Tetrapyrrole methylase
Superfamily: Tetrapyrrole methylase
Family: Tetrapyrrole methylase

Phyre2

PDB 3i4t chain A

3D model

Region: 218 - 457
Aligned: 229
Modelled: 240
Confidence: 100.0%
Identity: 18%
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:diphthine synthase;
PDBTitle: crystal structure of putative diphthine synthase from2 entamoeba histolytica

Phyre2

PDB 2dek chain A domain 1

3D model

Region: 217 - 451
Aligned: 233
Modelled: 235
Confidence: 100.0%
Identity: 18%
Fold: Tetrapyrrole methylase
Superfamily: Tetrapyrrole methylase
Family: Tetrapyrrole methylase

Phyre2

PDB 1vhv chain A

3D model

Region: 218 - 450
Aligned: 228
Modelled: 230
Confidence: 100.0%
Identity: 18%
Fold: Tetrapyrrole methylase
Superfamily: Tetrapyrrole methylase
Family: Tetrapyrrole methylase

Phyre2
1

c1pjtB_
2

d1s4da_
3

d1pjqa2
4

c2yboA_
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c1kyqC_
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d1cbfa_
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c1cbfA_
8

c3dfzB_
9

d1ve2a1
10

c3ndcB_
11

c3kwpA_
12

d1va0a1
13

c2zvbA_
14

d1wdea_
15

c3nutC_
16

c2e0kA_
17

d1wyza1
18

c3i4tA_
19

d2deka1
20

d1vhva_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c1pjtB_



100.0 90 PDB header:transferase/oxidoreductase/lyase
Chain: B: PDB Molecule:siroheme synthase;
PDBTitle: the structure of the ser128ala point-mutant variant of cysg,2 the multifunctional3 methyltransferase/dehydrogenase/ferrochelatase for4 siroheme synthesis
2d1s4da_



100.0 44 Fold:Tetrapyrrole methylase
Superfamily:Tetrapyrrole methylase
Family:Tetrapyrrole methylase
3d1pjqa2



100.0 91 Fold:Tetrapyrrole methylase
Superfamily:Tetrapyrrole methylase
Family:Tetrapyrrole methylase
4c2yboA_



100.0 55 PDB header:transferase
Chain: A: PDB Molecule:methyltransferase;
PDBTitle: the x-ray structure of the sam-dependent uroporphyrinogen2 iii methyltransferase nire from pseudomonas aeruginosa in3 complex with sah
5c1kyqC_



100.0 21 PDB header:oxidoreductase, lyase
Chain: C: PDB Molecule:siroheme biosynthesis protein met8;
PDBTitle: met8p: a bifunctional nad-dependent dehydrogenase and2 ferrochelatase involved in siroheme synthesis.
6d1cbfa_



100.0 30 Fold:Tetrapyrrole methylase
Superfamily:Tetrapyrrole methylase
Family:Tetrapyrrole methylase
7c1cbfA_



100.0 30 PDB header:methyltransferase
Chain: A: PDB Molecule:cobalt-precorrin-4 transmethylase;
PDBTitle: the x-ray structure of a cobalamin biosynthetic enzyme, cobalt2 precorrin-4 methyltransferase, cbif
8c3dfzB_



100.0 21 PDB header:oxidoreductase
Chain: B: PDB Molecule:precorrin-2 dehydrogenase;
PDBTitle: sirc, precorrin-2 dehydrogenase
9d1ve2a1



100.0 42 Fold:Tetrapyrrole methylase
Superfamily:Tetrapyrrole methylase
Family:Tetrapyrrole methylase
10c3ndcB_



100.0 32 PDB header:transferase
Chain: B: PDB Molecule:precorrin-4 c(11)-methyltransferase;
PDBTitle: crystal structure of precorrin-4 c11-methyltransferase from2 rhodobacter capsulatus
11c3kwpA_



100.0 19 PDB header:transferase
Chain: A: PDB Molecule:predicted methyltransferase;
PDBTitle: crystal structure of putative methyltransferase from lactobacillus2 brevis
12d1va0a1



100.0 39 Fold:Tetrapyrrole methylase
Superfamily:Tetrapyrrole methylase
Family:Tetrapyrrole methylase
13c2zvbA_



100.0 25 PDB header:transferase
Chain: A: PDB Molecule:precorrin-3 c17-methyltransferase;
PDBTitle: crystal structure of tt0207 from thermus thermophilus hb8
14d1wdea_



100.0 18 Fold:Tetrapyrrole methylase
Superfamily:Tetrapyrrole methylase
Family:Tetrapyrrole methylase
15c3nutC_



100.0 21 PDB header:transferase
Chain: C: PDB Molecule:precorrin-3 methylase;
PDBTitle: crystal structure of the methyltransferase cobj
16c2e0kA_



100.0 20 PDB header:transferase
Chain: A: PDB Molecule:precorrin-2 c20-methyltransferase;
PDBTitle: crystal structure of cbil, a methyltransferase involved in anaerobic2 vitamin b12 biosynthesis
17d1wyza1



100.0 14 Fold:Tetrapyrrole methylase
Superfamily:Tetrapyrrole methylase
Family:Tetrapyrrole methylase
18c3i4tA_



100.0 18 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:diphthine synthase;
PDBTitle: crystal structure of putative diphthine synthase from2 entamoeba histolytica
19d2deka1



100.0 18 Fold:Tetrapyrrole methylase
Superfamily:Tetrapyrrole methylase
Family:Tetrapyrrole methylase
20d1vhva_



100.0 18 Fold:Tetrapyrrole methylase
Superfamily:Tetrapyrrole methylase
Family:Tetrapyrrole methylase
21c2qbuA_



not modelled 100.0 21 PDB header:transferase
Chain: A: PDB Molecule:precorrin-2 methyltransferase;
PDBTitle: crystal structure of methanothermobacter thermautotrophicus cbil
22c2npnA_



not modelled 100.0 19 PDB header:transferase
Chain: A: PDB Molecule:putative cobalamin synthesis related protein;
PDBTitle: crystal structure of putative cobalamin synthesis related protein2 (cobf) from corynebacterium diphtheriae
23c3nd1B_



not modelled 100.0 21 PDB header:transferase
Chain: B: PDB Molecule:precorrin-6a synthase/cobf protein;
PDBTitle: crystal structure of precorrin-6a synthase from rhodobacter capsulatus
24c2bb3B_



not modelled 100.0 20 PDB header:transferase
Chain: B: PDB Molecule:cobalamin biosynthesis precorrin-6y methylase (cbie);
PDBTitle: crystal structure of cobalamin biosynthesis precorrin-6y methylase2 (cbie) from archaeoglobus fulgidus
25d2bb3a1



not modelled 100.0 18 Fold:Tetrapyrrole methylase
Superfamily:Tetrapyrrole methylase
Family:Tetrapyrrole methylase
26d1kyqa1



not modelled 100.0 21 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Siroheme synthase N-terminal domain-like
27d1pjqa1



not modelled 100.0 90 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Siroheme synthase N-terminal domain-like
28c3hh1D_



not modelled 99.9 19 PDB header:transferase
Chain: D: PDB Molecule:tetrapyrrole methylase family protein;
PDBTitle: the structure of a tetrapyrrole methylase family protein domain from2 chlorobium tepidum tls
29d1pjqa3



not modelled 99.8 87 Fold:Siroheme synthase middle domains-like
Superfamily:Siroheme synthase middle domains-like
Family:Siroheme synthase middle domains-like
30d1kyqa2



not modelled 99.5 20 Fold:Siroheme synthase middle domains-like
Superfamily:Siroheme synthase middle domains-like
Family:Siroheme synthase middle domains-like
31c3fq6A_



not modelled 99.0 19 PDB header:transferase
Chain: A: PDB Molecule:methyltransferase;
PDBTitle: the crystal structure of a methyltransferase domain from bacteroides2 thetaiotaomicron vpi
32c3d4oA_



not modelled 98.4 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:dipicolinate synthase subunit a;
PDBTitle: crystal structure of dipicolinate synthase subunit a (np_243269.1)2 from bacillus halodurans at 2.10 a resolution
33c2rirA_



not modelled 98.2 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:dipicolinate synthase, a chain;
PDBTitle: crystal structure of dipicolinate synthase, a chain, from bacillus2 subtilis
34d2jfga1



not modelled 98.1 16 Fold:MurCD N-terminal domain
Superfamily:MurCD N-terminal domain
Family:MurCD N-terminal domain
35d1lssa_



not modelled 97.8 19 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Potassium channel NAD-binding domain
36d1e5qa1



not modelled 97.7 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
37c2g1uA_



not modelled 97.6 22 PDB header:transport protein
Chain: A: PDB Molecule:hypothetical protein tm1088a;
PDBTitle: crystal structure of a putative transport protein (tm1088a) from2 thermotoga maritima at 1.50 a resolution
38d1li4a1



not modelled 97.6 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
39c3gvpB_



not modelled 97.6 18 PDB header:hydrolase
Chain: B: PDB Molecule:adenosylhomocysteinase 3;
PDBTitle: human sahh-like domain of human adenosylhomocysteinase 3
40c1gpjA_



not modelled 97.6 19 PDB header:reductase
Chain: A: PDB Molecule:glutamyl-trna reductase;
PDBTitle: glutamyl-trna reductase from methanopyrus kandleri
41c1y8qA_



not modelled 97.5 16 PDB header:ligase
Chain: A: PDB Molecule:ubiquitin-like 1 activating enzyme e1a;
PDBTitle: sumo e1 activating enzyme sae1-sae2-mg-atp complex
42c1d4fD_



not modelled 97.5 18 PDB header:hydrolase
Chain: D: PDB Molecule:s-adenosylhomocysteine hydrolase;
PDBTitle: crystal structure of recombinant rat-liver d244e mutant s-2 adenosylhomocysteine hydrolase
43c3fwzA_



not modelled 97.5 17 PDB header:membrane protein
Chain: A: PDB Molecule:inner membrane protein ybal;
PDBTitle: crystal structure of trka-n domain of inner membrane protein ybal from2 escherichia coli
44d1p3da1



not modelled 97.5 17 Fold:MurCD N-terminal domain
Superfamily:MurCD N-terminal domain
Family:MurCD N-terminal domain
45c3llvA_



not modelled 97.5 20 PDB header:nad(p) binding protein
Chain: A: PDB Molecule:exopolyphosphatase-related protein;
PDBTitle: the crystal structure of the nad(p)-binding domain of an2 exopolyphosphatase-related protein from archaeoglobus fulgidus to3 1.7a
46c3dhyC_



not modelled 97.5 22 PDB header:hydrolase
Chain: C: PDB Molecule:adenosylhomocysteinase;
PDBTitle: crystal structures of mycobacterium tuberculosis s-adenosyl-l-2 homocysteine hydrolase in ternary complex with substrate and3 inhibitors
47d1jw9b_



not modelled 97.5 29 Fold:Activating enzymes of the ubiquitin-like proteins
Superfamily:Activating enzymes of the ubiquitin-like proteins
Family:Molybdenum cofactor biosynthesis protein MoeB
48c3l4bG_



not modelled 97.4 17 PDB header:transport protein
Chain: G: PDB Molecule:trka k+ channel protien tm1088b;
PDBTitle: crystal structure of an octomeric two-subunit trka k+ channel ring2 gating assembly, tm1088a:tm1088b, from thermotoga maritima
49c3n58D_



not modelled 97.4 21 PDB header:hydrolase
Chain: D: PDB Molecule:adenosylhomocysteinase;
PDBTitle: crystal structure of s-adenosyl-l-homocysteine hydrolase from brucella2 melitensis in ternary complex with nad and adenosine, orthorhombic3 form
50c3gucB_



not modelled 97.4 14 PDB header:transferase
Chain: B: PDB Molecule:ubiquitin-like modifier-activating enzyme 5;
PDBTitle: human ubiquitin-activating enzyme 5 in complex with amppnp
51c3d64A_



not modelled 97.4 21 PDB header:hydrolase
Chain: A: PDB Molecule:adenosylhomocysteinase;
PDBTitle: crystal structure of s-adenosyl-l-homocysteine hydrolase from2 burkholderia pseudomallei
52c3eywA_



not modelled 97.4 23 PDB header:transport protein
Chain: A: PDB Molecule:c-terminal domain of glutathione-regulated potassium-efflux
PDBTitle: crystal structure of the c-terminal domain of e. coli kefc in complex2 with keff
53d1gpja2



not modelled 97.4 20 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Aminoacid dehydrogenase-like, C-terminal domain
54c1zfnA_



not modelled 97.4 29 PDB header:transferase
Chain: A: PDB Molecule:adenylyltransferase thif;
PDBTitle: structural analysis of escherichia coli thif
55c1v8bA_



not modelled 97.3 18 PDB header:hydrolase
Chain: A: PDB Molecule:adenosylhomocysteinase;
PDBTitle: crystal structure of a hydrolase
56c3oneA_



not modelled 97.3 20 PDB header:hydrolase/hydrolase substrate
Chain: A: PDB Molecule:adenosylhomocysteinase;
PDBTitle: crystal structure of lupinus luteus s-adenosyl-l-homocysteine2 hydrolase in complex with adenine
57d1v8ba1



not modelled 97.3 17 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
58c3ic5A_



not modelled 97.2 18 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:putative saccharopine dehydrogenase;
PDBTitle: n-terminal domain of putative saccharopine dehydrogenase from ruegeria2 pomeroyi.
59d1j6ua1



not modelled 97.2 15 Fold:MurCD N-terminal domain
Superfamily:MurCD N-terminal domain
Family:MurCD N-terminal domain
60c2f00A_



not modelled 97.1 22 PDB header:ligase
Chain: A: PDB Molecule:udp-n-acetylmuramate--l-alanine ligase;
PDBTitle: escherichia coli murc
61c2axqA_



not modelled 97.1 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:saccharopine dehydrogenase;
PDBTitle: apo histidine-tagged saccharopine dehydrogenase (l-glu2 forming) from saccharomyces cerevisiae
62d2hmva1



not modelled 97.1 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Potassium channel NAD-binding domain
63c1e5lA_



not modelled 97.1 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:saccharopine reductase;
PDBTitle: apo saccharopine reductase from magnaporthe grisea
64d1f0ya2



not modelled 97.1 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
65d1gdha1



not modelled 97.1 12 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
66d1np3a2



not modelled 97.0 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
67c3gznB_



not modelled 97.0 12 PDB header:protein binding/ligase
Chain: B: PDB Molecule:nedd8-activating enzyme e1 catalytic subunit;
PDBTitle: structure of nedd8-activating enzyme in complex with nedd82 and mln4924
68c3c85A_



not modelled 97.0 16 PDB header:transport protein
Chain: A: PDB Molecule:putative glutathione-regulated potassium-efflux system
PDBTitle: crystal structure of trka domain of putative glutathione-regulated2 potassium-efflux kefb from vibrio parahaemolyticus
69d1ygya1



not modelled 97.0 15 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
70c3uagA_



not modelled 97.0 16 PDB header:ligase
Chain: A: PDB Molecule:protein (udp-n-acetylmuramoyl-l-alanine:d-
PDBTitle: udp-n-acetylmuramoyl-l-alanine:d-glutamate ligase
71c1y8qD_



not modelled 97.0 16 PDB header:ligase
Chain: D: PDB Molecule:ubiquitin-like 2 activating enzyme e1b;
PDBTitle: sumo e1 activating enzyme sae1-sae2-mg-atp complex
72c3hn7A_



not modelled 97.0 15 PDB header:ligase
Chain: A: PDB Molecule:udp-n-acetylmuramate-l-alanine ligase;
PDBTitle: crystal structure of a murein peptide ligase mpl (psyc_0032) from2 psychrobacter arcticus 273-4 at 1.65 a resolution
73c1wwkA_



not modelled 96.9 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:phosphoglycerate dehydrogenase;
PDBTitle: crystal structure of phosphoglycerate dehydrogenase from pyrococcus2 horikoshii ot3
74c3pgjB_



not modelled 96.9 19 PDB header:oxidoreductase
Chain: B: PDB Molecule:shikimate dehydrogenase;
PDBTitle: 2.49 angstrom resolution crystal structure of shikimate 5-2 dehydrogenase (aroe) from vibrio cholerae o1 biovar eltor str. n169613 in complex with shikimate
75c3kydB_



not modelled 96.9 15 PDB header:ligase
Chain: B: PDB Molecule:sumo-activating enzyme subunit 2;
PDBTitle: human sumo e1~sumo1-amp tetrahedral intermediate mimic
76c2eezG_



not modelled 96.9 17 PDB header:oxidoreductase
Chain: G: PDB Molecule:alanine dehydrogenase;
PDBTitle: crystal structure of alanine dehydrogenase from themus thermophilus
77c2nvuB_



not modelled 96.9 12 PDB header:protein turnover, ligase
Chain: B: PDB Molecule:maltose binding protein/nedd8-activating enzyme
PDBTitle: structure of appbp1-uba3~nedd8-nedd8-mgatp-ubc12(c111a), a2 trapped ubiquitin-like protein activation complex
78d1id1a_



not modelled 96.9 22 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Potassium channel NAD-binding domain
79d2naca1



not modelled 96.9 13 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
80c2hk8B_



not modelled 96.9 17 PDB header:oxidoreductase
Chain: B: PDB Molecule:shikimate dehydrogenase;
PDBTitle: crystal structure of shikimate dehydrogenase from aquifex2 aeolicus at 2.35 angstrom resolution
81c1np3B_



not modelled 96.8 16 PDB header:oxidoreductase
Chain: B: PDB Molecule:ketol-acid reductoisomerase;
PDBTitle: crystal structure of class i acetohydroxy acid isomeroreductase from2 pseudomonas aeruginosa
82c1gdhA_



not modelled 96.8 12 PDB header:oxidoreductase(choh (d)-nad(p)+ (a))
Chain: A: PDB Molecule:d-glycerate dehydrogenase;
PDBTitle: crystal structure of a nad-dependent d-glycerate2 dehydrogenase at 2.4 angstroms resolution
83c3h9gA_



not modelled 96.8 12 PDB header:transferase/antibiotic
Chain: A: PDB Molecule:mccb protein;
PDBTitle: crystal structure of e. coli mccb + mcca-n7isoasn
84c2eggA_



not modelled 96.8 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:shikimate 5-dehydrogenase;
PDBTitle: crystal structure of shikimate 5-dehydrogenase (aroe) from2 geobacillus kaustophilus
85d1j4aa1



not modelled 96.7 15 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
86c2g76A_



not modelled 96.7 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:d-3-phosphoglycerate dehydrogenase;
PDBTitle: crystal structure of human 3-phosphoglycerate dehydrogenase
87d1l7da1



not modelled 96.7 11 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
88c2g5cD_



not modelled 96.7 13 PDB header:oxidoreductase
Chain: D: PDB Molecule:prephenate dehydrogenase;
PDBTitle: crystal structure of prephenate dehydrogenase from aquifex aeolicus
89d1pjca1



not modelled 96.6 17 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
90c1nytC_



not modelled 96.6 17 PDB header:oxidoreductase
Chain: C: PDB Molecule:shikimate 5-dehydrogenase;
PDBTitle: shikimate dehydrogenase aroe complexed with nadp+
91d2fy8a1



not modelled 96.6 15 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Potassium channel NAD-binding domain
92d1mx3a1



not modelled 96.6 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
93c3pwzA_



not modelled 96.6 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:shikimate dehydrogenase 3;
PDBTitle: crystal structure of an ael1 enzyme from pseudomonas putida
94c3vh3A_



not modelled 96.6 18 PDB header:metal binding protein/protein transport
Chain: A: PDB Molecule:ubiquitin-like modifier-activating enzyme atg7;
PDBTitle: crystal structure of atg7ctd-atg8 complex
95c1j4aA_



not modelled 96.6 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:d-lactate dehydrogenase;
PDBTitle: insights into domain closure, substrate specificity and2 catalysis of d-lactate dehydrogenase from lactobacillus3 bulgaricus
96c2f1kD_



not modelled 96.5 16 PDB header:oxidoreductase
Chain: D: PDB Molecule:prephenate dehydrogenase;
PDBTitle: crystal structure of synechocystis arogenate dehydrogenase
97c2dbqA_



not modelled 96.5 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:glyoxylate reductase;
PDBTitle: crystal structure of glyoxylate reductase (ph0597) from pyrococcus2 horikoshii ot3, complexed with nadp (i41)
98d1nyta1



not modelled 96.5 19 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Aminoacid dehydrogenase-like, C-terminal domain
99d2f1ka2



not modelled 96.5 17 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
100c3g0oA_



not modelled 96.5 20 PDB header:oxidoreductase
Chain: A: PDB Molecule:3-hydroxyisobutyrate dehydrogenase;
PDBTitle: crystal structure of 3-hydroxyisobutyrate dehydrogenase2 (ygbj) from salmonella typhimurium
101c3evtA_



not modelled 96.5 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:phosphoglycerate dehydrogenase;
PDBTitle: crystal structure of phosphoglycerate dehydrogenase from2 lactobacillus plantarum
102d1yovb1



not modelled 96.5 11 Fold:Activating enzymes of the ubiquitin-like proteins
Superfamily:Activating enzymes of the ubiquitin-like proteins
Family:Ubiquitin activating enzymes (UBA)
103c3d1lB_



not modelled 96.4 17 PDB header:oxidoreductase
Chain: B: PDB Molecule:putative nadp oxidoreductase bf3122;
PDBTitle: crystal structure of putative nadp oxidoreductase bf3122 from2 bacteroides fragilis
104c3vh1A_



not modelled 96.4 16 PDB header:metal binding protein
Chain: A: PDB Molecule:ubiquitin-like modifier-activating enzyme atg7;
PDBTitle: crystal structure of saccharomyces cerevisiae atg7 (1-595)
105c3b1fA_



not modelled 96.4 10 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative prephenate dehydrogenase;
PDBTitle: crystal structure of prephenate dehydrogenase from streptococcus2 mutans
106c3cmmA_



not modelled 96.4 14 PDB header:ligase/protein binding
Chain: A: PDB Molecule:ubiquitin-activating enzyme e1 1;
PDBTitle: crystal structure of the uba1-ubiquitin complex
107c3hwrA_



not modelled 96.4 22 PDB header:oxidoreductase
Chain: A: PDB Molecule:2-dehydropantoate 2-reductase;
PDBTitle: crystal structure of pane/apba family ketopantoate reductase2 (yp_299159.1) from ralstonia eutropha jmp134 at 2.15 a resolution
108c3o8qB_



not modelled 96.4 23 PDB header:oxidoreductase
Chain: B: PDB Molecule:shikimate 5-dehydrogenase i alpha;
PDBTitle: 1.45 angstrom resolution crystal structure of shikimate 5-2 dehydrogenase (aroe) from vibrio cholerae
109c2pv7B_



not modelled 96.4 14 PDB header:isomerase, oxidoreductase
Chain: B: PDB Molecule:t-protein [includes: chorismate mutase (ec 5.4.99.5) (cm)
PDBTitle: crystal structure of chorismate mutase / prephenate dehydrogenase2 (tyra) (1574749) from haemophilus influenzae rd at 2.00 a resolution
110c3cumA_



not modelled 96.3 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:probable 3-hydroxyisobutyrate dehydrogenase;
PDBTitle: crystal structure of a possible 3-hydroxyisobutyrate dehydrogenase2 from pseudomonas aeruginosa pao1
111d1nvta1



not modelled 96.3 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Aminoacid dehydrogenase-like, C-terminal domain
112c3oj0A_



not modelled 96.3 25 PDB header:oxidoreductase
Chain: A: PDB Molecule:glutamyl-trna reductase;
PDBTitle: crystal structure of glutamyl-trna reductase from thermoplasma2 volcanium (nucleotide binding domain)
113c3n7uD_



not modelled 96.3 13 PDB header:oxidoreductase
Chain: D: PDB Molecule:formate dehydrogenase;
PDBTitle: nad-dependent formate dehydrogenase from higher-plant arabidopsis2 thaliana in complex with nad and azide
114c1l7eC_



not modelled 96.3 8 PDB header:oxidoreductase
Chain: C: PDB Molecule:nicotinamide nucleotide transhydrogenase,
PDBTitle: crystal structure of r. rubrum transhydrogenase domain i2 with bound nadh
115d1leha1



not modelled 96.3 20 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Aminoacid dehydrogenase-like, C-terminal domain
116d1txga2



not modelled 96.3 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
117c3kboB_



not modelled 96.2 16 PDB header:oxidoreductase
Chain: B: PDB Molecule:glyoxylate/hydroxypyruvate reductase a;
PDBTitle: 2.14 angstrom crystal structure of putative oxidoreductase (ycdw) from2 salmonella typhimurium in complex with nadp
118c3bazA_



not modelled 96.2 12 PDB header:oxidoreductase
Chain: A: PDB Molecule:hydroxyphenylpyruvate reductase;
PDBTitle: structure of hydroxyphenylpyruvate reductase from coleus blumei in2 complex with nadp+
119d2gz1a1



not modelled 96.2 11 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
120c2nloA_



not modelled 96.2 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:shikimate dehydrogenase;
PDBTitle: crystal structure of the quinate dehydrogenase from corynebacterium2 glutamicum

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0