Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	E	R	Y	E	S	L	F	A	Q	L	K	E	R	K	E	G	A	F	V	P	F	V	T	L	G	D	P	G	I	E	Q	S	L	K	I	I	D	T	L	I	E	A	G	A	D	A	L	E	L	G	I	P	F	S	D	P	L	A	D
Secondary structure
SS confidence
Disorder		?	?	?										?		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		G	P	T	I	Q	N	A	T	L	R	A	F	A	A	G	V	T	P	A	Q	C	F	E	M	L	A	L	I	R	Q	K	H	P	T	I	P	I	G	L	L	M	Y	A	N	L	V	F	N	K	G	I	D	E	F	Y	A	Q	C	E	K
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		V	G	V	D	S	V	L	V	A	D	V	P	V	E	E	S	A	P	F	R	Q	A	A	L	R	H	N	V	A	P	I	F	I	C	P	P	N	A	D	D	D	L	L	R	Q	I	A	S	Y	G	R	G	Y	T	Y	L	L	S	R	A
Secondary structure
SS confidence
Disorder																																																												?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		G	V	T	G	A	E	N	R	A	A	L	P	L	N	H	L	V	A	K	L	K	E	Y	N	A	A	P	P	L	Q	G	F	G	I	S	A	P	D	Q	V	K	A	A	I	D	A	G	A	A	G	A	I	S	G	S	A	I	V	K	I
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.
Sequence		I	E	Q	H	I	N	E	P	E	K	M	L	A	A	L	K	V	F	V	Q	P	M	K	A	A	T	R	S
Secondary structure
SS confidence
Disorder				?		?	?	?																				?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3nav chain B Region: 1 - 267 Aligned: 256 Modelled: 267 Confidence: 100.0% Identity: 63% PDB header:lyase Chain: B: PDB Molecule:tryptophan synthase alpha chain; PDBTitle: crystal structure of an alpha subunit of tryptophan synthase from2 vibrio cholerae o1 biovar el tor str. n16961 Phyre2 PDB 1qop chain A Region: 1 - 267 Aligned: 265 Modelled: 267 Confidence: 100.0% Identity: 85% Fold: TIM beta/alpha-barrel Superfamily: Ribulose-phoshate binding barrel Family: Tryptophan biosynthesis enzymes Phyre2 PDB 2ekc chain A Region: 1 - 267 Aligned: 252 Modelled: 267 Confidence: 100.0% Identity: 32% PDB header:lyase Chain: A: PDB Molecule:tryptophan synthase alpha chain; PDBTitle: structural study of project id aq_1548 from aquifex aeolicus vf5 Phyre2 PDB 1ujp chain A Region: 1 - 268 Aligned: 239 Modelled: 268 Confidence: 100.0% Identity: 28% Fold: TIM beta/alpha-barrel Superfamily: Ribulose-phoshate binding barrel Family: Tryptophan biosynthesis enzymes Phyre2 PDB 3tha chain B Region: 12 - 260 Aligned: 243 Modelled: 249 Confidence: 100.0% Identity: 29% PDB header:lyase Chain: B: PDB Molecule:tryptophan synthase alpha chain; PDBTitle: tryptophan synthase subunit alpha from campylobacter jejuni. Phyre2 PDB 1rd5 chain A Region: 2 - 266 Aligned: 259 Modelled: 265 Confidence: 100.0% Identity: 31% Fold: TIM beta/alpha-barrel Superfamily: Ribulose-phoshate binding barrel Family: Tryptophan biosynthesis enzymes Phyre2 PDB 1geq chain A Region: 15 - 264 Aligned: 238 Modelled: 250 Confidence: 100.0% Identity: 34% Fold: TIM beta/alpha-barrel Superfamily: Ribulose-phoshate binding barrel Family: Tryptophan biosynthesis enzymes Phyre2 PDB 1xcf chain A Region: 1 - 267 Aligned: 238 Modelled: 238 Confidence: 100.0% Identity: 95% Fold: TIM beta/alpha-barrel Superfamily: Ribulose-phoshate binding barrel Family: Tryptophan biosynthesis enzymes Phyre2 PDB 1viz chain A Region: 22 - 251 Aligned: 213 Modelled: 230 Confidence: 100.0% Identity: 13% Fold: TIM beta/alpha-barrel Superfamily: FMN-linked oxidoreductases Family: FMN-linked oxidoreductases Phyre2 PDB 2f6u chain A domain 1 Region: 22 - 240 Aligned: 212 Modelled: 219 Confidence: 100.0% Identity: 15% Fold: TIM beta/alpha-barrel Superfamily: FMN-linked oxidoreductases Family: FMN-linked oxidoreductases Phyre2 PDB 3igs chain B Region: 33 - 265 Aligned: 218 Modelled: 233 Confidence: 100.0% Identity: 16% PDB header:isomerase Chain: B: PDB Molecule:n-acetylmannosamine-6-phosphate 2-epimerase 2; PDBTitle: structure of the salmonella enterica n-acetylmannosamine-6-phosphate2 2-epimerase Phyre2 PDB 1j5t chain A Region: 1 - 257 Aligned: 215 Modelled: 243 Confidence: 100.0% Identity: 16% Fold: TIM beta/alpha-barrel Superfamily: Ribulose-phoshate binding barrel Family: Tryptophan biosynthesis enzymes Phyre2 PDB 3q58 chain A Region: 33 - 260 Aligned: 216 Modelled: 220 Confidence: 100.0% Identity: 14% PDB header:isomerase Chain: A: PDB Molecule:n-acetylmannosamine-6-phosphate 2-epimerase; PDBTitle: structure of n-acetylmannosamine-6-phosphate epimerase from salmonella2 enterica Phyre2 PDB 3qc3 chain B Region: 19 - 265 Aligned: 213 Modelled: 227 Confidence: 100.0% Identity: 16% PDB header:isomerase Chain: B: PDB Molecule:d-ribulose-5-phosphate-3-epimerase; PDBTitle: crystal structure of a d-ribulose-5-phosphate-3-epimerase (np_954699)2 from homo sapiens at 2.20 a resolution Phyre2 PDB 1rpx chain A Region: 13 - 257 Aligned: 209 Modelled: 225 Confidence: 99.9% Identity: 14% Fold: TIM beta/alpha-barrel Superfamily: Ribulose-phoshate binding barrel Family: D-ribulose-5-phosphate 3-epimerase Phyre2 PDB 2c3z chain A Region: 4 - 242 Aligned: 202 Modelled: 225 Confidence: 99.9% Identity: 20% PDB header:lyase Chain: A: PDB Molecule:indole-3-glycerol phosphate synthase; PDBTitle: crystal structure of a truncated variant of indole-3-2 glycerol phosphate synthase from sulfolobus solfataricus Phyre2 PDB 3ct7 chain E Region: 19 - 268 Aligned: 207 Modelled: 230 Confidence: 99.9% Identity: 18% PDB header:isomerase Chain: E: PDB Molecule:d-allulose-6-phosphate 3-epimerase; PDBTitle: crystal structure of d-allulose 6-phosphate 3-epimerase2 from escherichia coli k-12 Phyre2 PDB 1tqx chain A Region: 16 - 261 Aligned: 213 Modelled: 226 Confidence: 99.9% Identity: 14% Fold: TIM beta/alpha-barrel Superfamily: Ribulose-phoshate binding barrel Family: D-ribulose-5-phosphate 3-epimerase Phyre2 PDB 3inp chain A Region: 19 - 262 Aligned: 211 Modelled: 224 Confidence: 99.9% Identity: 15% PDB header:isomerase Chain: A: PDB Molecule:d-ribulose-phosphate 3-epimerase; PDBTitle: 2.05 angstrom resolution crystal structure of d-ribulose-phosphate 3-2 epimerase from francisella tularensis. Phyre2 PDB 1y0e chain A Region: 47 - 260 Aligned: 205 Modelled: 214 Confidence: 99.9% Identity: 12% Fold: TIM beta/alpha-barrel Superfamily: Ribulose-phoshate binding barrel Family: NanE-like Phyre2 1 c3navB_ 2 d1qopa_ 3 c2ekcA_ 4 d1ujpa_ 5 c3thaB_ 6 d1rd5a_ 7 d1geqa_ 8 d1xcfa_ 9 d1viza_ 10 d2f6ua1 11 c3igsB_ 12 d1j5ta_ 13 c3q58A_ 14 c3qc3B_ 15 d1rpxa_ 16 c2c3zA_ 17 c3ct7E_ 18 d1tqxa_ 19 c3inpA_ 20 d1y0ea_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 306 307 308 309 310 311 312 313 314 315 316 317 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 336 337 338 339 340 341 342 343 344 345 346 347 348 349 350 351 352 353 354 355 356 357 358 359 360 361 362 363 364 365 366 367 368 369 370 371 372 373 374 375 376 377 378 379 380 381 382 383 384 385 386 387 388 389 390 391 392 393 394 395 396 397 398 399 400 401 402 403 404 405 406 407 408 409 410 411 412 413 414 415 416 417 418 419 420 421 422 423 424 425 426 427 428 429 430 431 432 433 434 435 436 437 438 439 440 441 442 443 444 445 446 447 448 449 450 451 452 453 454 455 456 457 458 459 460 461 462 463 464 465 466 467 468 469 470 471 472 473 474 475 476 477 478 479 480 481 482 483 484 485 486 487 488 489 490 491 492 493 494 495 496 497 498 499