Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP0C0U4
DateThu Jan 5 11:30:01 GMT 2012
Unique Job ID838468fd5c96273c

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c1gshA_
Top template information
PDB header:glutathione biosynthesis ligase
Chain: A: PDB Molecule:glutathione biosynthetic ligase;
PDBTitle: structure of escherichia coli glutathione synthetase at ph 7.5
Confidence and coverage
Confidence:100.0% Coverage: 90%
269 residues ( 90% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MKIAILSRDGTLYSCKRLREAAIQRGHLVEILDPLSCYMNINPAASSIHYKGRKLPHFDA
Secondary structure 
SS confidence 
Disorder  ?
Disorder confidence 
 
   .........70.........80.........90.........100.........110.........120
Sequence  VIPRIGTAITFYGTAALRQFEMLGSYPLNESVAIARARDKLRSMQLLARQGIDLPVTGIA
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........130.........140.........150.........160.........170.........180
Sequence  HSPDDTSDLIDMVGGAPLVVKLVEGTQGIGVVLAETRQAAESVIDAFRGLNAHILVQEYI
Secondary structure 
SS confidence 
Disorder 
?
Disorder confidence 
 
   .........190.........200.........210.........220.........230.........240
Sequence  KEAQGCDIRCLVVGDEVVAAIERRAKEGDFRSNLHRGGAASVASITPQEREIAIKAARTM
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........250.........260.........270.........280.........290.........300
Sequence  ALDVAGVDILRANRGPLVMEVNASPGLEGIEKTTGIDIAGKMIRWIERHATTEYCLKTGG
Secondary structure 
SS confidence 
Disorder 
?????????
Disorder confidence 
 
  
Sequence 
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1gsh chain A

3D model

Region: 1 - 293
Aligned: 269
Modelled: 281
Confidence: 100.0%
Identity: 19%
PDB header:glutathione biosynthesis ligase
Chain: A: PDB Molecule:glutathione biosynthetic ligase;
PDBTitle: structure of escherichia coli glutathione synthetase at ph 7.5

Phyre2

PDB 1kjj chain A

3D model

Region: 2 - 286
Aligned: 276
Modelled: 282
Confidence: 100.0%
Identity: 16%
PDB header:transferase
Chain: A: PDB Molecule:phosphoribosylglycinamide formyltransferase 2;
PDBTitle: crystal structure of glycniamide ribonucleotide2 transformylase in complex with mg-atp-gamma-s

Phyre2

PDB 1uc8 chain B

3D model

Region: 3 - 290
Aligned: 249
Modelled: 272
Confidence: 100.0%
Identity: 28%
PDB header:biosynthetic protein
Chain: B: PDB Molecule:lysine biosynthesis enzyme;
PDBTitle: crystal structure of a lysine biosynthesis enzyme, lysx,2 from thermus thermophilus hb8

Phyre2

PDB 1m6v chain E

3D model

Region: 2 - 285
Aligned: 283
Modelled: 284
Confidence: 100.0%
Identity: 19%
PDB header:ligase
Chain: E: PDB Molecule:carbamoyl phosphate synthetase large chain;
PDBTitle: crystal structure of the g359f (small subunit) point mutant of2 carbamoyl phosphate synthetase

Phyre2

PDB 3lwb chain A

3D model

Region: 1 - 291
Aligned: 290
Modelled: 291
Confidence: 100.0%
Identity: 19%
PDB header:ligase
Chain: A: PDB Molecule:d-alanine--d-alanine ligase;
PDBTitle: crystal structure of apo d-alanine:d-alanine ligase (ddl) from2 mycobacterium tuberculosis

Phyre2

PDB 3bg5 chain C

3D model

Region: 1 - 285
Aligned: 280
Modelled: 285
Confidence: 100.0%
Identity: 16%
PDB header:ligase
Chain: C: PDB Molecule:pyruvate carboxylase;
PDBTitle: crystal structure of staphylococcus aureus pyruvate2 carboxylase

Phyre2

PDB 3i12 chain A

3D model

Region: 1 - 293
Aligned: 292
Modelled: 293
Confidence: 100.0%
Identity: 17%
PDB header:ligase
Chain: A: PDB Molecule:d-alanine-d-alanine ligase a;
PDBTitle: the crystal structure of the d-alanyl-alanine synthetase a from2 salmonella enterica subsp. enterica serovar typhimurium str. lt2

Phyre2

PDB 2dzd chain B

3D model

Region: 1 - 285
Aligned: 280
Modelled: 285
Confidence: 100.0%
Identity: 16%
PDB header:ligase
Chain: B: PDB Molecule:pyruvate carboxylase;
PDBTitle: crystal structure of the biotin carboxylase domain of2 pyruvate carboxylase

Phyre2

PDB 2dln chain A

3D model

Region: 1 - 287
Aligned: 272
Modelled: 283
Confidence: 100.0%
Identity: 20%
PDB header:ligase(peptidoglycan synthesis)
Chain: A: PDB Molecule:d-alanine--d-alanine ligase;
PDBTitle: vancomycin resistance: structure of d-alanine:d-alanine2 ligase at 2.3 angstroms resolution

Phyre2

PDB 3se7 chain A

3D model

Region: 1 - 288
Aligned: 283
Modelled: 288
Confidence: 100.0%
Identity: 16%
PDB header:ligase
Chain: A: PDB Molecule:vana;
PDBTitle: ancient vana

Phyre2

PDB 2i80 chain B

3D model

Region: 2 - 287
Aligned: 282
Modelled: 283
Confidence: 100.0%
Identity: 17%
PDB header:ligase
Chain: B: PDB Molecule:d-alanine-d-alanine ligase;
PDBTitle: allosteric inhibition of staphylococcus aureus d-alanine:d-alanine2 ligase revealed by crystallographic studies

Phyre2

PDB 2pvp chain B

3D model

Region: 1 - 284
Aligned: 275
Modelled: 284
Confidence: 100.0%
Identity: 14%
PDB header:ligase
Chain: B: PDB Molecule:d-alanine-d-alanine ligase;
PDBTitle: crystal structure of d-alanine-d-alanine ligase from helicobacter2 pylori

Phyre2

PDB 3g8c chain B

3D model

Region: 1 - 285
Aligned: 281
Modelled: 285
Confidence: 100.0%
Identity: 17%
PDB header:ligase
Chain: B: PDB Molecule:biotin carboxylase;
PDBTitle: crystal stucture of biotin carboxylase in complex with2 biotin, bicarbonate, adp and mg ion

Phyre2

PDB 1e4e chain B

3D model

Region: 1 - 287
Aligned: 283
Modelled: 287
Confidence: 100.0%
Identity: 17%
PDB header:ligase
Chain: B: PDB Molecule:vancomycin/teicoplanin a-type resistance protein vana;
PDBTitle: d-alanyl-d-lacate ligase

Phyre2

PDB 3e5n chain A

3D model

Region: 1 - 295
Aligned: 286
Modelled: 295
Confidence: 100.0%
Identity: 17%
PDB header:ligase
Chain: A: PDB Molecule:d-alanine-d-alanine ligase a;
PDBTitle: crystal strucutre of d-alanine-d-alanine ligase from2 xanthomonas oryzae pv. oryzae kacc10331

Phyre2

PDB 1ulz chain A

3D model

Region: 2 - 285
Aligned: 278
Modelled: 284
Confidence: 100.0%
Identity: 16%
PDB header:ligase
Chain: A: PDB Molecule:pyruvate carboxylase n-terminal domain;
PDBTitle: crystal structure of the biotin carboxylase subunit of pyruvate2 carboxylase

Phyre2

PDB 3tqt chain B

3D model

Region: 1 - 287
Aligned: 273
Modelled: 274
Confidence: 100.0%
Identity: 19%
PDB header:ligase
Chain: B: PDB Molecule:d-alanine--d-alanine ligase;
PDBTitle: structure of the d-alanine-d-alanine ligase from coxiella burnetii

Phyre2

PDB 3ouz chain A

3D model

Region: 1 - 285
Aligned: 280
Modelled: 278
Confidence: 100.0%
Identity: 16%
PDB header:ligase
Chain: A: PDB Molecule:biotin carboxylase;
PDBTitle: crystal structure of biotin carboxylase-adp complex from campylobacter2 jejuni

Phyre2

PDB 1ehi chain B

3D model

Region: 2 - 300
Aligned: 291
Modelled: 299
Confidence: 100.0%
Identity: 16%
PDB header:ligase
Chain: B: PDB Molecule:d-alanine:d-lactate ligase;
PDBTitle: d-alanine:d-lactate ligase (lmddl2) of vancomycin-resistant2 leuconostoc mesenteroides

Phyre2

PDB 3etj chain B

3D model

Region: 1 - 286
Aligned: 257
Modelled: 268
Confidence: 100.0%
Identity: 15%
PDB header:lyase
Chain: B: PDB Molecule:phosphoribosylaminoimidazole carboxylase atpase
PDBTitle: crystal structure e. coli purk in complex with mg, adp, and2 pi

Phyre2
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c1gshA_
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c1kjjA_
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c1uc8B_
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c1m6vE_
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c3lwbA_
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c3bg5C_
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c3i12A_
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c2dzdB_
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c2dlnA_
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c3se7A_
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c2i80B_
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c2pvpB_
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c3g8cB_
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c1e4eB_
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c3e5nA_
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c1ulzA_
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c3tqtB_
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c3ouzA_
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c1ehiB_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c1gshA_
100.0 19 PDB header:glutathione biosynthesis ligase
Chain: A: PDB Molecule:glutathione biosynthetic ligase;
PDBTitle: structure of escherichia coli glutathione synthetase at ph 7.5
2c1kjjA_
100.0 16 PDB header:transferase
Chain: A: PDB Molecule:phosphoribosylglycinamide formyltransferase 2;
PDBTitle: crystal structure of glycniamide ribonucleotide2 transformylase in complex with mg-atp-gamma-s
3c1uc8B_
100.0 28 PDB header:biosynthetic protein
Chain: B: PDB Molecule:lysine biosynthesis enzyme;
PDBTitle: crystal structure of a lysine biosynthesis enzyme, lysx,2 from thermus thermophilus hb8
4c1m6vE_
100.0 19 PDB header:ligase
Chain: E: PDB Molecule:carbamoyl phosphate synthetase large chain;
PDBTitle: crystal structure of the g359f (small subunit) point mutant of2 carbamoyl phosphate synthetase
5c3lwbA_
100.0 19 PDB header:ligase
Chain: A: PDB Molecule:d-alanine--d-alanine ligase;
PDBTitle: crystal structure of apo d-alanine:d-alanine ligase (ddl) from2 mycobacterium tuberculosis
6c3bg5C_
100.0 16 PDB header:ligase
Chain: C: PDB Molecule:pyruvate carboxylase;
PDBTitle: crystal structure of staphylococcus aureus pyruvate2 carboxylase
7c3i12A_
100.0 17 PDB header:ligase
Chain: A: PDB Molecule:d-alanine-d-alanine ligase a;
PDBTitle: the crystal structure of the d-alanyl-alanine synthetase a from2 salmonella enterica subsp. enterica serovar typhimurium str. lt2
8c2dzdB_
100.0 16 PDB header:ligase
Chain: B: PDB Molecule:pyruvate carboxylase;
PDBTitle: crystal structure of the biotin carboxylase domain of2 pyruvate carboxylase
9c2dlnA_
100.0 20 PDB header:ligase(peptidoglycan synthesis)
Chain: A: PDB Molecule:d-alanine--d-alanine ligase;
PDBTitle: vancomycin resistance: structure of d-alanine:d-alanine2 ligase at 2.3 angstroms resolution
10c3se7A_
100.0 16 PDB header:ligase
Chain: A: PDB Molecule:vana;
PDBTitle: ancient vana
11c2i80B_
100.0 17 PDB header:ligase
Chain: B: PDB Molecule:d-alanine-d-alanine ligase;
PDBTitle: allosteric inhibition of staphylococcus aureus d-alanine:d-alanine2 ligase revealed by crystallographic studies
12c2pvpB_
100.0 14 PDB header:ligase
Chain: B: PDB Molecule:d-alanine-d-alanine ligase;
PDBTitle: crystal structure of d-alanine-d-alanine ligase from helicobacter2 pylori
13c3g8cB_
100.0 17 PDB header:ligase
Chain: B: PDB Molecule:biotin carboxylase;
PDBTitle: crystal stucture of biotin carboxylase in complex with2 biotin, bicarbonate, adp and mg ion
14c1e4eB_
100.0 17 PDB header:ligase
Chain: B: PDB Molecule:vancomycin/teicoplanin a-type resistance protein vana;
PDBTitle: d-alanyl-d-lacate ligase
15c3e5nA_
100.0 17 PDB header:ligase
Chain: A: PDB Molecule:d-alanine-d-alanine ligase a;
PDBTitle: crystal strucutre of d-alanine-d-alanine ligase from2 xanthomonas oryzae pv. oryzae kacc10331
16c1ulzA_
100.0 16 PDB header:ligase
Chain: A: PDB Molecule:pyruvate carboxylase n-terminal domain;
PDBTitle: crystal structure of the biotin carboxylase subunit of pyruvate2 carboxylase
17c3tqtB_
100.0 19 PDB header:ligase
Chain: B: PDB Molecule:d-alanine--d-alanine ligase;
PDBTitle: structure of the d-alanine-d-alanine ligase from coxiella burnetii
18c3ouzA_
100.0 16 PDB header:ligase
Chain: A: PDB Molecule:biotin carboxylase;
PDBTitle: crystal structure of biotin carboxylase-adp complex from campylobacter2 jejuni
19c1ehiB_
100.0 16 PDB header:ligase
Chain: B: PDB Molecule:d-alanine:d-lactate ligase;
PDBTitle: d-alanine:d-lactate ligase (lmddl2) of vancomycin-resistant2 leuconostoc mesenteroides
20c3etjB_
100.0 15 PDB header:lyase
Chain: B: PDB Molecule:phosphoribosylaminoimidazole carboxylase atpase
PDBTitle: crystal structure e. coli purk in complex with mg, adp, and2 pi
21c2zdqA_
not modelled 100.0 17 PDB header:ligase
Chain: A: PDB Molecule:d-alanine--d-alanine ligase;
PDBTitle: crystal structure of d-alanine:d-alanine ligase with atp2 and d-alanine:d-alanine from thermus thermophius hb8
22c2vpqA_
not modelled 100.0 15 PDB header:ligase
Chain: A: PDB Molecule:acetyl-coa carboxylase;
PDBTitle: crystal structure of biotin carboxylase from s. aureus2 complexed with amppnp
23c2xd4A_
not modelled 100.0 20 PDB header:ligase
Chain: A: PDB Molecule:phosphoribosylamine--glycine ligase;
PDBTitle: nucleotide-bound structures of bacillus subtilis glycinamide2 ribonucleotide synthetase
24c3q2oB_
not modelled 100.0 15 PDB header:lyase
Chain: B: PDB Molecule:phosphoribosylaminoimidazole carboxylase, atpase subunit;
PDBTitle: crystal structure of purk: n5-carboxyaminoimidazole ribonucleotide2 synthetase
25c2yyaB_
not modelled 100.0 17 PDB header:ligase
Chain: B: PDB Molecule:phosphoribosylamine--glycine ligase;
PDBTitle: crystal structure of gar synthetase from aquifex aeolicus
26c3lp8A_
not modelled 100.0 18 PDB header:ligase
Chain: A: PDB Molecule:phosphoribosylamine-glycine ligase;
PDBTitle: crystal structure of phosphoribosylamine-glycine ligase from2 ehrlichia chaffeensis
27c1w96B_
not modelled 100.0 17 PDB header:ligase
Chain: B: PDB Molecule:acetyl-coenzyme a carboxylase;
PDBTitle: crystal structure of biotin carboxylase domain of acetyl-2 coenzyme a carboxylase from saccharomyces cerevisiae in3 complex with soraphen a
28c3uvzB_
not modelled 100.0 15 PDB header:lyase
Chain: B: PDB Molecule:phosphoribosylaminoimidazole carboxylase, atpase subunit;
PDBTitle: crystal structure of phosphoribosylaminoimidazole carboxylase, atpase2 subunit from burkholderia ambifaria
29c3ln6A_
not modelled 100.0 25 PDB header:ligase
Chain: A: PDB Molecule:glutathione biosynthesis bifunctional protein gshab;
PDBTitle: crystal structure of a bifunctional glutathione synthetase from2 streptococcus agalactiae
30c2hjwA_
not modelled 100.0 17 PDB header:ligase
Chain: A: PDB Molecule:acetyl-coa carboxylase 2;
PDBTitle: crystal structure of the bc domain of acc2
31c3r23B_
not modelled 100.0 15 PDB header:ligase
Chain: B: PDB Molecule:d-alanine--d-alanine ligase;
PDBTitle: crystal structure of d-alanine--d-alanine ligase from bacillus2 anthracis
32c1vkzA_
not modelled 100.0 14 PDB header:ligase
Chain: A: PDB Molecule:phosphoribosylamine--glycine ligase;
PDBTitle: crystal structure of phosphoribosylamine--glycine ligase (tm1250) from2 thermotoga maritima at 2.30 a resolution
33c3gidB_
not modelled 100.0 17 PDB header:ligase
Chain: B: PDB Molecule:acetyl-coa carboxylase 2;
PDBTitle: the biotin carboxylase (bc) domain of human acetyl-coa2 carboxylase 2 (acc2) in complex with soraphen a
34c3ln7A_
not modelled 100.0 22 PDB header:ligase
Chain: A: PDB Molecule:glutathione biosynthesis bifunctional protein gshab;
PDBTitle: crystal structure of a bifunctional glutathione synthetase from2 pasteurella multocida
35c3orqA_
not modelled 100.0 15 PDB header:ligase,biosynthetic protein
Chain: A: PDB Molecule:n5-carboxyaminoimidazole ribonucleotide synthetase;
PDBTitle: crystal structure of n5-carboxyaminoimidazole synthetase from2 staphylococcus aureus complexed with adp
36c2dwcB_
not modelled 100.0 19 PDB header:transferase
Chain: B: PDB Molecule:433aa long hypothetical phosphoribosylglycinamide formyl
PDBTitle: crystal structure of probable phosphoribosylglycinamide formyl2 transferase from pyrococcus horikoshii ot3 complexed with adp
37c2ip4A_
not modelled 100.0 17 PDB header:ligase
Chain: A: PDB Molecule:phosphoribosylamine--glycine ligase;
PDBTitle: crystal structure of glycinamide ribonucleotide synthetase from2 thermus thermophilus hb8
38c2gpwC_
not modelled 100.0 16 PDB header:ligase
Chain: C: PDB Molecule:biotin carboxylase;
PDBTitle: crystal structure of the biotin carboxylase subunit, f363a2 mutant, of acetyl-coa carboxylase from escherichia coli.
39c2p0aA_
not modelled 100.0 14 PDB header:neuropeptide
Chain: A: PDB Molecule:synapsin-3;
PDBTitle: the crystal structure of human synapsin iii (syn3) in complex with2 amppnp
40c3u9sE_
not modelled 100.0 19 PDB header:ligase
Chain: E: PDB Molecule:methylcrotonyl-coa carboxylase, alpha-subunit;
PDBTitle: crystal structure of p. aeruginosa 3-methylcrotonyl-coa carboxylase2 (mcc) 750 kd holoenzyme, coa complex
41c2ys6A_
not modelled 100.0 18 PDB header:ligase
Chain: A: PDB Molecule:phosphoribosylglycinamide synthetase;
PDBTitle: crystal structure of gar synthetase from geobacillus kaustophilus
42c3k5iB_
not modelled 100.0 15 PDB header:lyase
Chain: B: PDB Molecule:phosphoribosyl-aminoimidazole carboxylase;
PDBTitle: crystal structure of n5-carboxyaminoimidazole synthase from2 aspergillus clavatus in complex with adp and 5-3 aminoimadazole ribonucleotide
43c3k3pA_
not modelled 100.0 13 PDB header:ligase
Chain: A: PDB Molecule:d-alanine--d-alanine ligase;
PDBTitle: crystal structure of the apo form of d-alanine:d-alanine ligase (ddl)2 from streptococcus mutans
44c2qb5B_
not modelled 100.0 18 PDB header:transferase
Chain: B: PDB Molecule:inositol-tetrakisphosphate 1-kinase;
PDBTitle: crystal structure of human inositol 1,3,4-trisphosphate 5/6-kinase2 (itpk1) in complex with adp and mn2+
45c1pk8D_
not modelled 100.0 13 PDB header:membrane protein
Chain: D: PDB Molecule:rat synapsin i;
PDBTitle: crystal structure of rat synapsin i c domain complexed to2 ca.atp
46c3n6rK_
not modelled 100.0 17 PDB header:ligase
Chain: K: PDB Molecule:propionyl-coa carboxylase, alpha subunit;
PDBTitle: crystal structure of the holoenzyme of propionyl-coa carboxylase (pcc)
47c1i7nA_
not modelled 100.0 16 PDB header:neuropeptide
Chain: A: PDB Molecule:synapsin ii;
PDBTitle: crystal structure analysis of the c domain of synapsin ii2 from rat brain
48c2qk4A_
not modelled 100.0 12 PDB header:ligase
Chain: A: PDB Molecule:trifunctional purine biosynthetic protein adenosine-3;
PDBTitle: human glycinamide ribonucleotide synthetase
49c2pn1A_
not modelled 99.9 17 PDB header:ligase
Chain: A: PDB Molecule:carbamoylphosphate synthase large subunit;
PDBTitle: crystal structure of carbamoylphosphate synthase large subunit (split2 gene in mj) (zp_00538348.1) from exiguobacterium sp. 255-15 at 2.00 a3 resolution
50c1gsoA_
not modelled 99.9 17 PDB header:ligase
Chain: A: PDB Molecule:protein (glycinamide ribonucleotide synthetase);
PDBTitle: glycinamide ribonucleotide synthetase (gar-syn) from e.2 coli.
51c2r85B_
not modelled 99.9 16 PDB header:unknown function
Chain: B: PDB Molecule:purp protein pf1517;
PDBTitle: crystal structure of purp from pyrococcus furiosus complexed with amp
52c2z04A_
not modelled 99.9 14 PDB header:lyase
Chain: A: PDB Molecule:phosphoribosylaminoimidazole carboxylase atpase
PDBTitle: crystal structure of phosphoribosylaminoimidazole2 carboxylase atpase subunit from aquifex aeolicus
53d1uc8a2
not modelled 99.9 29 Fold:ATP-grasp
Superfamily:Glutathione synthetase ATP-binding domain-like
Family:Lysine biosynthesis enzyme LysX ATP-binding domain
54c3t9aA_
not modelled 99.9 18 PDB header:transferase
Chain: A: PDB Molecule:inositol pyrophosphate kinase;
PDBTitle: crystal structure of the catalytic domain of human diphosphoinositol2 pentakisphosphate kinase 2 (ppip5k2) in complex with amppnp at ph 7.0
55c3df7A_
not modelled 99.9 19 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:putative atp-grasp superfamily protein;
PDBTitle: crystal structure of a putative atp-grasp superfamily2 protein from archaeoglobus fulgidus
56c1z2pX_
not modelled 99.9 15 PDB header:transferase
Chain: X: PDB Molecule:inositol 1,3,4-trisphosphate 5/6-kinase;
PDBTitle: inositol 1,3,4-trisphosphate 5/6-kinase in complex with mg2+/amp-2 pcp/ins(1,3,4)p3
57d1ehia2
not modelled 99.9 18 Fold:ATP-grasp
Superfamily:Glutathione synthetase ATP-binding domain-like
Family:ATP-binding domain of peptide synthetases
58d1e4ea2
not modelled 99.9 19 Fold:ATP-grasp
Superfamily:Glutathione synthetase ATP-binding domain-like
Family:ATP-binding domain of peptide synthetases
59d1w96a3
not modelled 99.9 16 Fold:ATP-grasp
Superfamily:Glutathione synthetase ATP-binding domain-like
Family:BC ATP-binding domain-like
60d1iowa2
not modelled 99.9 16 Fold:ATP-grasp
Superfamily:Glutathione synthetase ATP-binding domain-like
Family:ATP-binding domain of peptide synthetases
61d2j9ga3
not modelled 99.9 17 Fold:ATP-grasp
Superfamily:Glutathione synthetase ATP-binding domain-like
Family:BC ATP-binding domain-like
62d1kjqa3
not modelled 99.9 14 Fold:ATP-grasp
Superfamily:Glutathione synthetase ATP-binding domain-like
Family:BC ATP-binding domain-like
63d1a9xa5
not modelled 99.9 17 Fold:ATP-grasp
Superfamily:Glutathione synthetase ATP-binding domain-like
Family:BC ATP-binding domain-like
64d3etja3
not modelled 99.9 13 Fold:ATP-grasp
Superfamily:Glutathione synthetase ATP-binding domain-like
Family:BC ATP-binding domain-like
65d1pk8a2
not modelled 99.9 16 Fold:ATP-grasp
Superfamily:Glutathione synthetase ATP-binding domain-like
Family:Synapsin C-terminal domain
66d1vkza3
not modelled 99.9 14 Fold:ATP-grasp
Superfamily:Glutathione synthetase ATP-binding domain-like
Family:BC ATP-binding domain-like
67d1ulza3
not modelled 99.9 17 Fold:ATP-grasp
Superfamily:Glutathione synthetase ATP-binding domain-like
Family:BC ATP-binding domain-like
68d1gsaa2
not modelled 99.9 23 Fold:ATP-grasp
Superfamily:Glutathione synthetase ATP-binding domain-like
Family:ATP-binding domain of peptide synthetases
69d1i7na2
not modelled 99.9 16 Fold:ATP-grasp
Superfamily:Glutathione synthetase ATP-binding domain-like
Family:Synapsin C-terminal domain
70d1a9xa6
not modelled 99.8 16 Fold:ATP-grasp
Superfamily:Glutathione synthetase ATP-binding domain-like
Family:BC ATP-binding domain-like
71d2r7ka2
not modelled 99.8 13 Fold:ATP-grasp
Superfamily:Glutathione synthetase ATP-binding domain-like
Family:PurP ATP-binding domain-like
72d2r85a2
not modelled 99.8 17 Fold:ATP-grasp
Superfamily:Glutathione synthetase ATP-binding domain-like
Family:PurP ATP-binding domain-like
73d1gsoa3
not modelled 99.8 16 Fold:ATP-grasp
Superfamily:Glutathione synthetase ATP-binding domain-like
Family:BC ATP-binding domain-like
74c2qf7A_
not modelled 99.8 21 PDB header:ligase
Chain: A: PDB Molecule:pyruvate carboxylase protein;
PDBTitle: crystal structure of a complete multifunctional pyruvate carboxylase2 from rhizobium etli
75c2cqyA_
not modelled 99.0 15 PDB header:ligase
Chain: A: PDB Molecule:propionyl-coa carboxylase alpha chain,
PDBTitle: solution structure of b domain from human propionyl-coa2 carboxylase alpha subunit
76c2r7mA_
not modelled 98.9 17 PDB header:ligase
Chain: A: PDB Molecule:5-formaminoimidazole-4-carboxamide-1-(beta)-d-
PDBTitle: crystal structure of faicar synthetase (purp) from m.2 jannaschii complexed with amp
77d1gsaa1
not modelled 98.7 18 Fold:PreATP-grasp domain
Superfamily:PreATP-grasp domain
Family:Prokaryotic glutathione synthetase, N-terminal domain
78d1uc8a1
not modelled 98.5 23 Fold:PreATP-grasp domain
Superfamily:PreATP-grasp domain
Family:Lysine biosynthesis enzyme LysX, N-terminal domain
79c2pbzC_
not modelled 98.4 12 PDB header:ligase
Chain: C: PDB Molecule:hypothetical protein;
PDBTitle: crystal structure of an imp biosynthesis protein purp from2 thermococcus kodakaraensis
80d1a9xa4
not modelled 98.4 21 Fold:PreATP-grasp domain
Superfamily:PreATP-grasp domain
Family:BC N-terminal domain-like
81d1kjqa2
not modelled 98.3 19 Fold:PreATP-grasp domain
Superfamily:PreATP-grasp domain
Family:BC N-terminal domain-like
82c3tinA_
not modelled 98.3 19 PDB header:ligase
Chain: A: PDB Molecule:ttl protein;
PDBTitle: tubulin tyrosine ligase
83d1eucb2
not modelled 98.0 15 Fold:ATP-grasp
Superfamily:Glutathione synthetase ATP-binding domain-like
Family:Succinyl-CoA synthetase, beta-chain, N-terminal domain
84c2nu9E_
not modelled 98.0 23 PDB header:ligase
Chain: E: PDB Molecule:succinyl-coa synthetase beta chain;
PDBTitle: c123at mutant of e. coli succinyl-coa synthetase2 orthorhombic crystal form
85c1wr2A_
not modelled 97.8 17 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:hypothetical protein ph1789;
PDBTitle: crystal structure of ph1788 from pyrococcus horikoshii ot3
86c1eucB_
not modelled 97.7 18 PDB header:ligase
Chain: B: PDB Molecule:succinyl-coa synthetase, beta chain;
PDBTitle: crystal structure of dephosphorylated pig heart, gtp-2 specific succinyl-coa synthetase
87d2nu7b2
not modelled 97.6 23 Fold:ATP-grasp
Superfamily:Glutathione synthetase ATP-binding domain-like
Family:Succinyl-CoA synthetase, beta-chain, N-terminal domain
88d1a9xa3
not modelled 97.6 25 Fold:PreATP-grasp domain
Superfamily:PreATP-grasp domain
Family:BC N-terminal domain-like
89d1iowa1
not modelled 97.5 22 Fold:PreATP-grasp domain
Superfamily:PreATP-grasp domain
Family:D-Alanine ligase N-terminal domain
90d2pbza2
not modelled 97.4 12 Fold:ATP-grasp
Superfamily:Glutathione synthetase ATP-binding domain-like
Family:PurP ATP-binding domain-like
91d1ulza2
not modelled 96.8 16 Fold:PreATP-grasp domain
Superfamily:PreATP-grasp domain
Family:BC N-terminal domain-like
92c3mwdA_
not modelled 96.7 16 PDB header:transferase
Chain: A: PDB Molecule:atp-citrate synthase;
PDBTitle: truncated human atp-citrate lyase with citrate bound
93d2j9ga2
not modelled 96.6 13 Fold:PreATP-grasp domain
Superfamily:PreATP-grasp domain
Family:BC N-terminal domain-like
94c2ioaA_
not modelled 95.8 14 PDB header:ligase, hydrolase
Chain: A: PDB Molecule:bifunctional glutathionylspermidine
PDBTitle: e. coli bifunctional glutathionylspermidine2 synthetase/amidase incomplex with mg2+ and adp and3 phosphinate inhibitor
95c3n6xA_
not modelled 95.4 18 PDB header:ligase
Chain: A: PDB Molecule:putative glutathionylspermidine synthase;
PDBTitle: crystal structure of a putative glutathionylspermidine synthase2 (mfla_0391) from methylobacillus flagellatus kt at 2.35 a resolution
96c3eywA_
not modelled 95.3 16 PDB header:transport protein
Chain: A: PDB Molecule:c-terminal domain of glutathione-regulated potassium-efflux
PDBTitle: crystal structure of the c-terminal domain of e. coli kefc in complex2 with keff
97d1e4ea1
not modelled 94.7 14 Fold:PreATP-grasp domain
Superfamily:PreATP-grasp domain
Family:D-Alanine ligase N-terminal domain
98c3m2pD_
not modelled 94.0 29 PDB header:isomerase
Chain: D: PDB Molecule:udp-n-acetylglucosamine 4-epimerase;
PDBTitle: the crystal structure of udp-n-acetylglucosamine 4-epimerase2 from bacillus cereus
99c2pk3B_
not modelled 93.8 18 PDB header:oxidoreductase
Chain: B: PDB Molecule:gdp-6-deoxy-d-lyxo-4-hexulose reductase;
PDBTitle: crystal structure of a gdp-4-keto-6-deoxy-d-mannose reductase
100c3icpA_
not modelled 93.7 23 PDB header:isomerase
Chain: A: PDB Molecule:nad-dependent epimerase/dehydratase;
PDBTitle: crystal structure of udp-galactose 4-epimerase
101c2x4gA_
not modelled 93.7 19 PDB header:isomerase
Chain: A: PDB Molecule:nucleoside-diphosphate-sugar epimerase;
PDBTitle: crystal structure of pa4631, a nucleoside-diphosphate-sugar2 epimerase from pseudomonas aeruginosa
102d1udca_
not modelled 93.6 29 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
103c2issF_
not modelled 93.6 24 PDB header:lyase, transferase
Chain: F: PDB Molecule:glutamine amidotransferase subunit pdxt;
PDBTitle: structure of the plp synthase holoenzyme from thermotoga maritima
104d2a9va1
not modelled 93.5 13 Fold:Flavodoxin-like
Superfamily:Class I glutamine amidotransferase-like
Family:Class I glutamine amidotransferases (GAT)
105d1w96a2
not modelled 93.4 14 Fold:PreATP-grasp domain
Superfamily:PreATP-grasp domain
Family:BC N-terminal domain-like
106d2blla1
not modelled 93.4 21 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
107c2p5uC_
not modelled 93.2 26 PDB header:isomerase
Chain: C: PDB Molecule:udp-glucose 4-epimerase;
PDBTitle: crystal structure of thermus thermophilus hb8 udp-glucose 4-2 epimerase complex with nad
108d2c5aa1
not modelled 93.1 15 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
109c2pzlB_
not modelled 93.1 32 PDB header:sugar binding protein
Chain: B: PDB Molecule:putative nucleotide sugar epimerase/ dehydratase;
PDBTitle: crystal structure of the bordetella bronchiseptica enzyme2 wbmg in complex with nad and udp
110d2f1ka2
not modelled 93.0 24 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
111d1lssa_
not modelled 92.5 24 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Potassium channel NAD-binding domain
112c2jjmH_
not modelled 92.4 22 PDB header:transferase
Chain: H: PDB Molecule:glycosyl transferase, group 1 family protein;
PDBTitle: crystal structure of a family gt4 glycosyltransferase from2 bacillus anthracis orf ba1558.
113d1vl0a_
not modelled 92.3 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
114c2p6pB_
not modelled 92.2 22 PDB header:transferase
Chain: B: PDB Molecule:glycosyl transferase;
PDBTitle: x-ray crystal structure of c-c bond-forming dtdp-d-olivose-transferase2 urdgt2
115d2nv0a1
not modelled 91.9 21 Fold:Flavodoxin-like
Superfamily:Class I glutamine amidotransferase-like
Family:Class I glutamine amidotransferases (GAT)
116d1mv8a2
not modelled 91.8 30 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
117c2ggsB_
not modelled 91.8 18 PDB header:oxidoreductase
Chain: B: PDB Molecule:273aa long hypothetical dtdp-4-dehydrorhamnose
PDBTitle: crystal structure of hypothetical dtdp-4-dehydrorhamnose2 reductase from sulfolobus tokodaii
118c3oh8A_
not modelled 91.8 16 PDB header:isomerase
Chain: A: PDB Molecule:nucleoside-diphosphate sugar epimerase (sula family);
PDBTitle: crystal structure of the nucleoside-diphosphate sugar epimerase from2 corynebacterium glutamicum. northeast structural genomics consortium3 target cgr91
119c2q1wC_
not modelled 91.6 29 PDB header:sugar binding protein
Chain: C: PDB Molecule:putative nucleotide sugar epimerase/ dehydratase;
PDBTitle: crystal structure of the bordetella bronchiseptica enzyme wbmh in2 complex with nad+
120c2f1kD_
not modelled 91.4 24 PDB header:oxidoreductase
Chain: D: PDB Molecule:prephenate dehydrogenase;
PDBTitle: crystal structure of synechocystis arogenate dehydrogenase

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0