Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	A	I	H	N	R	A	G	Q	P	A	Q	Q	S	D	L	I	N	V	A	Q	L	T	A	Q	Y	Y	V	L	K	P	E	A	G	N	A	E	H	A	V	K	F	G	T	S	G	H	R	G	S	A	A	R	H	S	F	N	E	P	H
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?				?		?																?	?	?	?	?			?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		I	L	A	I	A	Q	A	I	A	E	E	R	A	K	N	G	I	T	G	P	C	Y	V	G	K	D	T	H	A	L	S	E	P	A	F	I	S	V	L	E	V	L	A	A	N	G	V	D	V	I	V	Q	E	N	N	G	F	T	P	T
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		P	A	V	S	N	A	I	L	V	H	N	K	K	G	G	P	L	A	D	G	I	V	I	T	P	S	H	N	P	P	E	D	G	G	I	K	Y	N	P	P	N	G	G	P	A	D	T	N	V	T	K	V	V	E	D	R	A	N	A	L
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		L	A	D	G	L	K	G	V	K	R	I	S	L	D	E	A	M	A	S	G	H	V	K	E	Q	D	L	V	Q	P	F	V	E	G	L	A	D	I	V	D	M	A	A	I	Q	K	A	G	L	T	L	G	V	D	P	L	G	G	S	G
Secondary structure
SS confidence
Disorder				?																																							?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		I	E	Y	W	K	R	I	G	E	Y	Y	N	L	N	L	T	I	V	N	D	Q	V	D	Q	T	F	R	F	M	H	L	D	K	D	G	A	I	R	M	D	C	S	S	E	C	A	M	A	G	L	L	A	L	R	D	K	F	D	L	A
Secondary structure
SS confidence
Disorder																																											?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		F	A	N	D	P	D	Y	D	R	H	G	I	V	T	P	A	G	L	M	N	P	N	H	Y	L	A	V	A	I	N	Y	L	F	Q	H	R	P	Q	W	G	K	D	V	A	V	G	K	T	L	V	S	S	A	M	I	D	R	V	V	N
Secondary structure
SS confidence
Disorder																																							?		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		D	L	G	R	K	L	V	E	V	P	V	G	F	K	W	F	V	D	G	L	F	D	G	S	F	G	F	G	G	E	E	S	A	G	A	S	F	L	R	F	D	G	T	P	W	S	T	D	K	D	G	I	I	M	C	L	L	A	A	E
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		I	T	A	V	T	G	K	N	P	Q	E	H	Y	N	E	L	A	K	R	F	G	A	P	S	Y	N	R	L	Q	A	A	A	T	S	A	Q	K	A	A	L	S	K	L	S	P	E	M	V	S	A	S	T	L	A	G	D	P	I	T	A
Secondary structure
SS confidence
Disorder																																															?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540
Sequence		R	L	T	A	A	P	G	N	G	A	S	I	G	G	L	K	V	M	T	D	N	G	W	F	A	A	R	P	S	G	T	E	D	A	Y	K	I	Y	C	E	S	F	L	G	E	E	H	R	K	Q	I	E	K	E	A	V	E	I	V	S
Secondary structure
SS confidence
Disorder						?	?	?
Disorder confidence
		.	.	.	.	.	.
Sequence		E	V	L	K	N	A
Secondary structure
SS confidence
Disorder						?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2fuv chain B Region: 2 - 546 Aligned: 545 Modelled: 544 Confidence: 100.0% Identity: 96% PDB header:isomerase Chain: B: PDB Molecule:phosphoglucomutase; PDBTitle: phosphoglucomutase from salmonella typhimurium. Phyre2 PDB 2z0f chain A Region: 17 - 543 Aligned: 490 Modelled: 496 Confidence: 100.0% Identity: 54% PDB header:isomerase Chain: A: PDB Molecule:putative phosphoglucomutase; PDBTitle: crystal structure of putative phosphoglucomutase from thermus2 thermophilus hb8 Phyre2 PDB 1kfi chain A Region: 33 - 544 Aligned: 502 Modelled: 506 Confidence: 100.0% Identity: 22% PDB header:isomerase Chain: A: PDB Molecule:phosphoglucomutase 1; PDBTitle: crystal structure of the exocytosis-sensitive2 phosphoprotein, pp63/parafusin (phosphoglucomutase) from3 paramecium Phyre2 PDB 1c4g chain B Region: 27 - 544 Aligned: 500 Modelled: 500 Confidence: 100.0% Identity: 26% PDB header:transferase Chain: B: PDB Molecule:protein (alpha-d-glucose 1-phosphate PDBTitle: phosphoglucomutase vanadate based transition state analog2 complex Phyre2 PDB 1wqa chain B Region: 42 - 543 Aligned: 448 Modelled: 479 Confidence: 100.0% Identity: 27% PDB header:isomerase Chain: B: PDB Molecule:phospho-sugar mutase; PDBTitle: crystal structure of pyrococcus horikoshii2 phosphomannomutase/phosphoglucomutase complexed with mg2+ Phyre2 PDB 2f7l chain A Region: 38 - 540 Aligned: 450 Modelled: 484 Confidence: 100.0% Identity: 23% PDB header:isomerase Chain: A: PDB Molecule:455aa long hypothetical phospho-sugar mutase; PDBTitle: crystal structure of sulfolobus tokodaii2 phosphomannomutase/phosphoglucomutase Phyre2 PDB 3c04 chain A Region: 42 - 546 Aligned: 444 Modelled: 449 Confidence: 100.0% Identity: 22% PDB header:isomerase Chain: A: PDB Molecule:phosphomannomutase/phosphoglucomutase; PDBTitle: structure of the p368g mutant of pmm/pgm from p. aeruginosa Phyre2 PDB 3pdk chain B Region: 42 - 543 Aligned: 439 Modelled: 478 Confidence: 100.0% Identity: 20% PDB header:isomerase Chain: B: PDB Molecule:phosphoglucosamine mutase; PDBTitle: crystal structure of phosphoglucosamine mutase from b. anthracis Phyre2 PDB 1tuo chain A Region: 36 - 540 Aligned: 432 Modelled: 458 Confidence: 100.0% Identity: 29% PDB header:biosynthetic protein Chain: A: PDB Molecule:putative phosphomannomutase; PDBTitle: crystal structure of putative phosphomannomutase from2 thermus thermophilus hb8 Phyre2 PDB 3i3w chain B Region: 42 - 543 Aligned: 436 Modelled: 475 Confidence: 100.0% Identity: 22% PDB header:isomerase Chain: B: PDB Molecule:phosphoglucosamine mutase; PDBTitle: structure of a phosphoglucosamine mutase from francisella tularensis Phyre2 PDB 2dkd chain A Region: 64 - 540 Aligned: 428 Modelled: 443 Confidence: 100.0% Identity: 20% PDB header:isomerase Chain: A: PDB Molecule:phosphoacetylglucosamine mutase; PDBTitle: crystal structure of n-acetylglucosamine-phosphate mutase,2 a member of the alpha-d-phosphohexomutase superfamily, in3 the product complex Phyre2 PDB 1kfi chain A domain 1 Region: 32 - 235 Aligned: 188 Modelled: 189 Confidence: 100.0% Identity: 24% Fold: Phosphoglucomutase, first 3 domains Superfamily: Phosphoglucomutase, first 3 domains Family: Phosphoglucomutase, first 3 domains Phyre2 PDB 3pmg chain A domain 1 Region: 33 - 221 Aligned: 179 Modelled: 189 Confidence: 100.0% Identity: 30% Fold: Phosphoglucomutase, first 3 domains Superfamily: Phosphoglucomutase, first 3 domains Family: Phosphoglucomutase, first 3 domains Phyre2 PDB 1p5d chain X domain 1 Region: 42 - 192 Aligned: 140 Modelled: 151 Confidence: 100.0% Identity: 25% Fold: Phosphoglucomutase, first 3 domains Superfamily: Phosphoglucomutase, first 3 domains Family: Phosphoglucomutase, first 3 domains Phyre2 PDB 3pmg chain A domain 3 Region: 321 - 441 Aligned: 115 Modelled: 121 Confidence: 99.9% Identity: 23% Fold: Phosphoglucomutase, first 3 domains Superfamily: Phosphoglucomutase, first 3 domains Family: Phosphoglucomutase, first 3 domains Phyre2 PDB 1kfi chain A domain 3 Region: 306 - 441 Aligned: 112 Modelled: 112 Confidence: 99.9% Identity: 29% Fold: Phosphoglucomutase, first 3 domains Superfamily: Phosphoglucomutase, first 3 domains Family: Phosphoglucomutase, first 3 domains Phyre2 PDB 1p5d chain X domain 3 Region: 321 - 435 Aligned: 107 Modelled: 115 Confidence: 99.9% Identity: 17% Fold: Phosphoglucomutase, first 3 domains Superfamily: Phosphoglucomutase, first 3 domains Family: Phosphoglucomutase, first 3 domains Phyre2 PDB 1p5d chain X domain 2 Region: 207 - 319 Aligned: 103 Modelled: 113 Confidence: 99.9% Identity: 22% Fold: Phosphoglucomutase, first 3 domains Superfamily: Phosphoglucomutase, first 3 domains Family: Phosphoglucomutase, first 3 domains Phyre2 PDB 1kfi chain A domain 2 Region: 208 - 319 Aligned: 112 Modelled: 112 Confidence: 99.9% Identity: 17% Fold: Phosphoglucomutase, first 3 domains Superfamily: Phosphoglucomutase, first 3 domains Family: Phosphoglucomutase, first 3 domains Phyre2 PDB 3pmg chain A domain 2 Region: 208 - 320 Aligned: 106 Modelled: 113 Confidence: 99.8% Identity: 25% Fold: Phosphoglucomutase, first 3 domains Superfamily: Phosphoglucomutase, first 3 domains Family: Phosphoglucomutase, first 3 domains Phyre2 1 c2fuvB_ 2 c2z0fA_ 3 c1kfiA_ 4 c1c4gB_ 5 c1wqaB_ 6 c2f7lA_ 7 c3c04A_ 8 c3pdkB_ 9 c1tuoA_ 10 c3i3wB_ 11 c2dkdA_ 12 d1kfia1 13 d3pmga1 14 d1p5dx1 15 d3pmga3 16 d1kfia3 17 d1p5dx3 18 d1p5dx2 19 d1kfia2 20 d3pmga2 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2fuvB_ 100.0 96 PDB header:isomerase Chain: B: PDB Molecule:phosphoglucomutase; PDBTitle: phosphoglucomutase from salmonella typhimurium. 2 c2z0fA_ 100.0 54 PDB header:isomerase Chain: A: PDB Molecule:putative phosphoglucomutase; PDBTitle: crystal structure of putative phosphoglucomutase from thermus2 thermophilus hb8 3 c1kfiA_ 100.0 22 PDB header:isomerase Chain: A: PDB Molecule:phosphoglucomutase 1; PDBTitle: crystal structure of the exocytosis-sensitive2 phosphoprotein, pp63/parafusin (phosphoglucomutase) from3 paramecium 4 c1c4gB_ 100.0 26 PDB header:transferase Chain: B: PDB Molecule:protein (alpha-d-glucose 1-phosphate PDBTitle: phosphoglucomutase vanadate based transition state analog2 complex 5 c1wqaB_ 100.0 27 PDB header:isomerase Chain: B: PDB Molecule:phospho-sugar mutase; PDBTitle: crystal structure of pyrococcus horikoshii2 phosphomannomutase/phosphoglucomutase complexed with mg2+ 6 c2f7lA_ 100.0 23 PDB header:isomerase Chain: A: PDB Molecule:455aa long hypothetical phospho-sugar mutase; PDBTitle: crystal structure of sulfolobus tokodaii2 phosphomannomutase/phosphoglucomutase 7 c3c04A_ 100.0 22 PDB header:isomerase Chain: A: PDB Molecule:phosphomannomutase/phosphoglucomutase; PDBTitle: structure of the p368g mutant of pmm/pgm from p. aeruginosa 8 c3pdkB_ 100.0 20 PDB header:isomerase Chain: B: PDB Molecule:phosphoglucosamine mutase; PDBTitle: crystal structure of phosphoglucosamine mutase from b. anthracis 9 c1tuoA_ 100.0 29 PDB header:biosynthetic protein Chain: A: PDB Molecule:putative phosphomannomutase; PDBTitle: crystal structure of putative phosphomannomutase from2 thermus thermophilus hb8 10 c3i3wB_ 100.0 22 PDB header:isomerase Chain: B: PDB Molecule:phosphoglucosamine mutase; PDBTitle: structure of a phosphoglucosamine mutase from francisella tularensis 11 c2dkdA_ 100.0 20 PDB header:isomerase Chain: A: PDB Molecule:phosphoacetylglucosamine mutase; PDBTitle: crystal structure of n-acetylglucosamine-phosphate mutase,2 a member of the alpha-d-phosphohexomutase superfamily, in3 the product complex 12 d1kfia1 100.0 24 Fold:Phosphoglucomutase, first 3 domains Superfamily:Phosphoglucomutase, first 3 domains Family:Phosphoglucomutase, first 3 domains 13 d3pmga1 100.0 30 Fold:Phosphoglucomutase, first 3 domains Superfamily:Phosphoglucomutase, first 3 domains Family:Phosphoglucomutase, first 3 domains 14 d1p5dx1 100.0 25 Fold:Phosphoglucomutase, first 3 domains Superfamily:Phosphoglucomutase, first 3 domains Family:Phosphoglucomutase, first 3 domains 15 d3pmga3 99.9 23 Fold:Phosphoglucomutase, first 3 domains Superfamily:Phosphoglucomutase, first 3 domains Family:Phosphoglucomutase, first 3 domains 16 d1kfia3 99.9 29 Fold:Phosphoglucomutase, first 3 domains Superfamily:Phosphoglucomutase, first 3 domains Family:Phosphoglucomutase, first 3 domains 17 d1p5dx3 99.9 17 Fold:Phosphoglucomutase, first 3 domains Superfamily:Phosphoglucomutase, first 3 domains Family:Phosphoglucomutase, first 3 domains 18 d1p5dx2 99.9 22 Fold:Phosphoglucomutase, first 3 domains Superfamily:Phosphoglucomutase, first 3 domains Family:Phosphoglucomutase, first 3 domains 19 d1kfia2 99.9 17 Fold:Phosphoglucomutase, first 3 domains Superfamily:Phosphoglucomutase, first 3 domains Family:Phosphoglucomutase, first 3 domains 20 d3pmga2 99.8 25 Fold:Phosphoglucomutase, first 3 domains Superfamily:Phosphoglucomutase, first 3 domains Family:Phosphoglucomutase, first 3 domains 21 d1p5dx4 not modelled 99.8 20 Fold:TBP-like Superfamily:Phosphoglucomutase, C-terminal domain Family:Phosphoglucomutase, C-terminal domain 22 d1wjwa_ not modelled 99.3 21 Fold:TBP-like Superfamily:Phosphoglucomutase, C-terminal domain Family:Phosphoglucomutase, C-terminal domain 23 d3pmga4 not modelled 98.1 17 Fold:TBP-like Superfamily:Phosphoglucomutase, C-terminal domain Family:Phosphoglucomutase, C-terminal domain 24 d1kfia4 not modelled 97.9 17 Fold:TBP-like Superfamily:Phosphoglucomutase, C-terminal domain Family:Phosphoglucomutase, C-terminal domain 25 c3s5pA_ not modelled 84.0 17 PDB header:isomerase Chain: A: PDB Molecule:ribose 5-phosphate isomerase; PDBTitle: crystal structure of ribose-5-phosphate isomerase b rpib from giardia2 lamblia 26 c3qayC_ not modelled 82.3 10 PDB header:lyase Chain: C: PDB Molecule:endolysin; PDBTitle: catalytic domain of cd27l endolysin targeting clostridia difficile 27 c3he8A_ not modelled 80.1 25 PDB header:isomerase Chain: A: PDB Molecule:ribose-5-phosphate isomerase; PDBTitle: structural study of clostridium thermocellum ribose-5-phosphate2 isomerase b 28 d1nn4a_ not modelled 80.0 22 Fold:Ribose/Galactose isomerase RpiB/AlsB Superfamily:Ribose/Galactose isomerase RpiB/AlsB Family:Ribose/Galactose isomerase RpiB/AlsB 29 d2vvpa1 not modelled 79.7 28 Fold:Ribose/Galactose isomerase RpiB/AlsB Superfamily:Ribose/Galactose isomerase RpiB/AlsB Family:Ribose/Galactose isomerase RpiB/AlsB 30 c2ppwA_ not modelled 78.8 13 PDB header:isomerase Chain: A: PDB Molecule:conserved domain protein; PDBTitle: the crystal structure of uncharacterized ribose 5-phosphate isomerase2 rpib from streptococcus pneumoniae 31 c3c5yD_ not modelled 76.0 16 PDB header:isomerase Chain: D: PDB Molecule:ribose/galactose isomerase; PDBTitle: crystal structure of a putative ribose 5-phosphate isomerase2 (saro_3514) from novosphingobium aromaticivorans dsm at 1.81 a3 resolution 32 d3bula2 not modelled 73.9 19 Fold:Flavodoxin-like Superfamily:Cobalamin (vitamin B12)-binding domain Family:Cobalamin (vitamin B12)-binding domain 33 c3ne8A_ not modelled 73.6 25 PDB header:hydrolase Chain: A: PDB Molecule:n-acetylmuramoyl-l-alanine amidase; PDBTitle: the crystal structure of a domain from n-acetylmuramoyl-l-alanine2 amidase of bartonella henselae str. houston-1 34 c3k7pA_ not modelled 70.0 12 PDB header:isomerase Chain: A: PDB Molecule:ribose 5-phosphate isomerase; PDBTitle: structure of mutant of ribose 5-phosphate isomerase type b from2 trypanosoma cruzi. 35 c3m1pA_ not modelled 70.0 12 PDB header:isomerase Chain: A: PDB Molecule:ribose 5-phosphate isomerase; PDBTitle: structure of ribose 5-phosphate isomerase type b from trypanosoma2 cruzi, soaked with allose-6-phosphate 36 c1k98A_ not modelled 65.6 19 PDB header:transferase Chain: A: PDB Molecule:methionine synthase; PDBTitle: adomet complex of meth c-terminal fragment 37 d1o1xa_ not modelled 59.5 18 Fold:Ribose/Galactose isomerase RpiB/AlsB Superfamily:Ribose/Galactose isomerase RpiB/AlsB Family:Ribose/Galactose isomerase RpiB/AlsB 38 c3k6qB_ not modelled 53.1 9 PDB header:ligand binding protein Chain: B: PDB Molecule:putative ligand binding protein; PDBTitle: crystal structure of an antitoxin part of a putative toxin/antitoxin2 system (swol_0700) from syntrophomonas wolfei subsp. wolfei at 1.80 a3 resolution 39 d1e5da1 not modelled 49.0 14 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:Flavodoxin-related 40 d2bl5a1 not modelled 44.9 24 Fold:Eukaryotic type KH-domain (KH-domain type I) Superfamily:Eukaryotic type KH-domain (KH-domain type I) Family:Eukaryotic type KH-domain (KH-domain type I) 41 c3onoA_ not modelled 44.3 10 PDB header:isomerase Chain: A: PDB Molecule:ribose/galactose isomerase; PDBTitle: crystal structure of ribose-5-phosphate isomerase lacab_rpib from2 vibrio parahaemolyticus 42 c2q9uB_ not modelled 44.2 10 PDB header:oxidoreductase Chain: B: PDB Molecule:a-type flavoprotein; PDBTitle: crystal structure of the flavodiiron protein from giardia2 intestinalis 43 d1x74a1 not modelled 42.1 10 Fold:CoA-transferase family III (CaiB/BaiF) Superfamily:CoA-transferase family III (CaiB/BaiF) Family:CoA-transferase family III (CaiB/BaiF) 44 d1ccwa_ not modelled 42.0 16 Fold:Flavodoxin-like Superfamily:Cobalamin (vitamin B12)-binding domain Family:Cobalamin (vitamin B12)-binding domain 45 c3op1A_ not modelled 41.6 15 PDB header:transferase Chain: A: PDB Molecule:macrolide-efflux protein; PDBTitle: crystal structure of macrolide-efflux protein sp_1110 from2 streptococcus pneumoniae 46 c2zkiH_ not modelled 41.2 12 PDB header:transcription Chain: H: PDB Molecule:199aa long hypothetical trp repressor binding PDBTitle: crystal structure of hypothetical trp repressor binding2 protein from sul folobus tokodaii (st0872) 47 d1gvfa_ not modelled 40.8 14 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class II FBP aldolase 48 c3nvtA_ not modelled 40.4 14 PDB header:transferase/isomerase Chain: A: PDB Molecule:3-deoxy-d-arabino-heptulosonate 7-phosphate synthase; PDBTitle: 1.95 angstrom crystal structure of a bifunctional 3-deoxy-7-2 phosphoheptulonate synthase/chorismate mutase (aroa) from listeria3 monocytogenes egd-e 49 c2i2xD_ not modelled 38.1 19 PDB header:transferase Chain: D: PDB Molecule:methyltransferase 1; PDBTitle: crystal structure of methanol:cobalamin methyltransferase complex2 mtabc from methanosarcina barkeri 50 c3a9rA_ not modelled 37.0 21 PDB header:isomerase Chain: A: PDB Molecule:d-arabinose isomerase; PDBTitle: x-ray structures of bacillus pallidus d-arabinose2 isomerasecomplex with (4r)-2-methylpentane-2,4-diol 51 c3pm6B_ not modelled 36.9 19 PDB header:lyase Chain: B: PDB Molecule:putative fructose-bisphosphate aldolase; PDBTitle: crystal structure of a putative fructose-1,6-biphosphate aldolase from2 coccidioides immitis solved by combined sad mr 52 d1yt8a4 not modelled 34.6 8 Fold:Rhodanese/Cell cycle control phosphatase Superfamily:Rhodanese/Cell cycle control phosphatase Family:Multidomain sulfurtransferase (rhodanese) 53 c1bmtB_ not modelled 33.9 18 PDB header:methyltransferase Chain: B: PDB Molecule:methionine synthase; PDBTitle: how a protein binds b12: a 3.o angstrom x-ray structure of2 the b12-binding domains of methionine synthase 54 c2ql5A_ not modelled 33.6 15 PDB header:hydrolase/hydrolase inhibitor Chain: A: PDB Molecule:caspase-7; PDBTitle: crystal structure of caspase-7 with inhibitor ac-dmqd-cho 55 d1t6t1_ not modelled 33.5 19 Fold:Toprim domain Superfamily:Toprim domain Family:Toprim domain 56 c3qd5B_ not modelled 33.1 20 PDB header:isomerase Chain: B: PDB Molecule:putative ribose-5-phosphate isomerase; PDBTitle: crystal structure of a putative ribose-5-phosphate isomerase from2 coccidioides immitis solved by combined iodide ion sad and mr 57 c1y80A_ not modelled 32.6 18 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:predicted cobalamin binding protein; PDBTitle: structure of a corrinoid (factor iiim)-binding protein from2 moorella thermoacetica 58 c2plqA_ not modelled 32.2 14 PDB header:hydrolase Chain: A: PDB Molecule:aliphatic amidase; PDBTitle: crystal structure of the amidase from geobacillus pallidus rapc8 59 c2iswB_ not modelled 32.2 16 PDB header:lyase Chain: B: PDB Molecule:putative fructose-1,6-bisphosphate aldolase; PDBTitle: structure of giardia fructose-1,6-biphosphate aldolase in2 complex with phosphoglycolohydroxamate 60 d1b0aa2 not modelled 30.7 18 Fold:Aminoacid dehydrogenase-like, N-terminal domain Superfamily:Aminoacid dehydrogenase-like, N-terminal domain Family:Tetrahydrofolate dehydrogenase/cyclohydrolase 61 d1ykga1 not modelled 30.0 16 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:Cytochrome p450 reductase N-terminal domain-like 62 d3eeqa2 not modelled 29.8 12 Fold:CbiG N-terminal domain-like Superfamily:CbiG N-terminal domain-like Family:CbiG N-terminal domain-like 63 c1pyoA_ not modelled 29.8 12 PDB header:hydrolase/hydrolase inhibitor Chain: A: PDB Molecule:caspase-2; PDBTitle: crystal structure of human caspase-2 in complex with acetyl-leu-asp-2 glu-ser-asp-cho 64 d1jwqa_ not modelled 27.9 15 Fold:Phosphorylase/hydrolase-like Superfamily:Zn-dependent exopeptidases Family:N-acetylmuramoyl-L-alanine amidase-like 65 d1a4ia2 not modelled 26.9 15 Fold:Aminoacid dehydrogenase-like, N-terminal domain Superfamily:Aminoacid dehydrogenase-like, N-terminal domain Family:Tetrahydrofolate dehydrogenase/cyclohydrolase 66 d7reqa2 not modelled 26.8 10 Fold:Flavodoxin-like Superfamily:Cobalamin (vitamin B12)-binding domain Family:Cobalamin (vitamin B12)-binding domain 67 d1vmea1 not modelled 25.6 16 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:Flavodoxin-related 68 c3qqzA_ not modelled 25.4 21 PDB header:metal binding protein Chain: A: PDB Molecule:putative uncharacterized protein yjik; PDBTitle: crystal structure of the c-terminal domain of the yjik protein from2 escherichia coli cft073 69 c1pyaD_ not modelled 25.2 19 PDB header:carboxy-lyase Chain: D: PDB Molecule:pyruvoyl-dependent histidine decarboxylase (l- PDBTitle: refined structure of the pyruvoyl-dependent histidine2 decarboxylase from lactobacillus 30a 70 c3hlyA_ not modelled 25.0 16 PDB header:flavoprotein Chain: A: PDB Molecule:flavodoxin-like domain; PDBTitle: crystal structure of the flavodoxin-like domain from2 synechococcus sp q5mzp6_synp6 protein. northeast structural3 genomics consortium target snr135d. 71 c3sz8D_ not modelled 24.1 11 PDB header:transferase Chain: D: PDB Molecule:2-dehydro-3-deoxyphosphooctonate aldolase 2; PDBTitle: crystal structure of 2-dehydro-3-deoxyphosphooctonate aldolase from2 burkholderia pseudomallei 72 c1i51A_ not modelled 23.5 15 PDB header:hydrolase/hydrolase inhibitor Chain: A: PDB Molecule:caspase-7 subunit p20; PDBTitle: crystal structure of caspase-7 complexed with xiap 73 d1jf8a_ not modelled 23.5 14 Fold:Phosphotyrosine protein phosphatases I-like Superfamily:Phosphotyrosine protein phosphatases I Family:Low-molecular-weight phosphotyrosine protein phosphatases 74 c3f93D_ not modelled 23.1 20 PDB header:hydrolase Chain: D: PDB Molecule:beta-glucosidase; PDBTitle: crystal structure of exo-1,3/1,4-beta-glucanase (exop) from2 pseudoalteromonas sp. bb1 75 d2nmla1 not modelled 22.8 13 Fold:ERH-like Superfamily:ERH-like Family:ERH-like 76 c2nn3D_ not modelled 22.3 15 PDB header:hydrolase Chain: D: PDB Molecule:caspase-1; PDBTitle: structure of pro-sf-caspase-1 77 d1rvga_ not modelled 22.2 20 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class II FBP aldolase 78 c3tqkA_ not modelled 22.1 16 PDB header:transferase Chain: A: PDB Molecule:phospho-2-dehydro-3-deoxyheptonate aldolase; PDBTitle: structure of phospho-2-dehydro-3-deoxyheptonate aldolase from2 francisella tularensis schu s4 79 d2aeea1 not modelled 21.5 15 Fold:PRTase-like Superfamily:PRTase-like Family:Phosphoribosyltransferases (PRTases) 80 c2w37A_ not modelled 21.0 18 PDB header:transferase Chain: A: PDB Molecule:ornithine carbamoyltransferase, catabolic; PDBTitle: crystal structure of the hexameric catabolic ornithine2 transcarbamylase from lactobacillus hilgardii 81 d1m72a_ not modelled 20.6 17 Fold:Caspase-like Superfamily:Caspase-like Family:Caspase catalytic domain 82 c3nolA_ not modelled 20.5 18 PDB header:transferase Chain: A: PDB Molecule:glutamine cyclotransferase; PDBTitle: crystal structure of zymomonas mobilis glutaminyl cyclase (trigonal2 form) 83 c3q94B_ not modelled 19.9 20 PDB header:lyase Chain: B: PDB Molecule:fructose-bisphosphate aldolase, class ii; PDBTitle: the crystal structure of fructose 1,6-bisphosphate aldolase from2 bacillus anthracis str. 'ames ancestor' 84 d1dxha2 not modelled 19.7 19 Fold:ATC-like Superfamily:Aspartate/ornithine carbamoyltransferase Family:Aspartate/ornithine carbamoyltransferase 85 c2if2C_ not modelled 19.0 11 PDB header:transferase Chain: C: PDB Molecule:dephospho-coa kinase; PDBTitle: crystal structure of the putative dephospho-coa kinase from aquifex2 aeolicus, northeast structural genomics target qr72. 86 c3mw8A_ not modelled 19.0 9 PDB header:lyase Chain: A: PDB Molecule:uroporphyrinogen-iii synthase; PDBTitle: crystal structure of an uroporphyrinogen-iii synthase (sama_3255) from2 shewanella amazonensis sb2b at 1.65 a resolution 87 d1ycga1 not modelled 18.9 17 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:Flavodoxin-related 88 c1qduI_ not modelled 18.7 5 PDB header:hydrolase/hydrolase inhibitor Chain: I: PDB Molecule:caspase-8 alpha-chain; PDBTitle: crystal structure of the complex of caspase-8 with the tripeptide2 ketone inhibitor zevd-dcbmk 89 c2wnsB_ not modelled 18.5 16 PDB header:transferase Chain: B: PDB Molecule:orotate phosphoribosyltransferase; PDBTitle: human orotate phosphoribosyltransferase (oprtase) domain of2 uridine 5'-monophosphate synthase (umps) in complex with3 its substrate orotidine 5'-monophosphate (omp) 90 d1tubb1 not modelled 18.4 16 Fold:Tubulin nucleotide-binding domain-like Superfamily:Tubulin nucleotide-binding domain-like Family:Tubulin, GTPase domain 91 d1k1ga_ not modelled 18.4 30 Fold:Eukaryotic type KH-domain (KH-domain type I) Superfamily:Eukaryotic type KH-domain (KH-domain type I) Family:Eukaryotic type KH-domain (KH-domain type I) 92 c2au3A_ not modelled 18.3 17 PDB header:transferase Chain: A: PDB Molecule:dna primase; PDBTitle: crystal structure of the aquifex aeolicus primase (zinc binding and2 rna polymerase domains) 93 c1a1sA_ not modelled 18.3 19 PDB header:transcarbamylase Chain: A: PDB Molecule:ornithine carbamoyltransferase; PDBTitle: ornithine carbamoyltransferase from pyrococcus furiosus 94 c3chgB_ not modelled 17.7 16 PDB header:ligand binding protein Chain: B: PDB Molecule:glycine betaine-binding protein; PDBTitle: the compatible solute-binding protein opuac from bacillus2 subtilis in complex with dmsa 95 c3edqC_ not modelled 17.6 7 PDB header:hydrolase/hydrolase inhibitor Chain: C: PDB Molecule:caspase-3; PDBTitle: crystal structure of caspase-3 with inhibitor ac-ldesd-cho 96 c3hdtB_ not modelled 17.2 16 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative kinase; PDBTitle: crystal structure of putative kinase from clostridium symbiosum atcc2 14940 97 c3c52B_ not modelled 16.9 30 PDB header:lyase Chain: B: PDB Molecule:fructose-bisphosphate aldolase; PDBTitle: class ii fructose-1,6-bisphosphate aldolase from2 helicobacter pylori in complex with3 phosphoglycolohydroxamic acid, a competitive inhibitor 98 c2p2gD_ not modelled 16.2 22 PDB header:transferase Chain: D: PDB Molecule:ornithine carbamoyltransferase; PDBTitle: crystal structure of ornithine carbamoyltransferase from mycobacterium2 tuberculosis (rv1656): orthorhombic form 99 c1tvmA_ not modelled 16.1 13 PDB header:transferase Chain: A: PDB Molecule:pts system, galactitol-specific iib component; PDBTitle: nmr structure of enzyme gatb of the galactitol-specific2 phosphoenolpyruvate-dependent phosphotransferase system

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0