Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	R	F	L	L	G	V	L	M	L	M	I	S	G	S	A	L	A	T	I	D	V	L	Q	F	K	D	E	A	Q	E	Q	Q	F	R	Q	L	T	E	E	L	R	C	P	K	C	Q	N	N	S	I	A	D	S	N	S	M	I	A	T
Secondary structure
SS confidence
Disorder		?												?	?				?	?	?	?	?	?	?	?	?	?																											?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		D	L	R	Q	K	V	Y	E	L	M	Q	E	G	K	S	K	K	E	I	V	D	Y	M	V	A	R	Y	G	N	F	V	T	Y	D	P	P	L	T	P	L	T	V	L	L	W	V	L	P	V	V	A	I	G	I	G	G	W	V	I	Y
Secondary structure
SS confidence
Disorder													?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		A	R	S	R	R	R	V	R	V	V	P	E	A	F	P	E	Q	S	V	P	E	G	K	R	A	G	Y	V	V	Y	L	P	G	I	V	V	A	L	I	V	A	G	V	S	Y	Y	Q	T	G	N	Y	Q	Q	V	K	I	W	Q	Q	A
Secondary structure
SS confidence
Disorder				?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		T	A	Q	A	P	A	L	L	D	R	A	L	D	P	K	A	D	P	L	N	E	E	E	M	S	R	L	A	L	G	M	R	T	Q	L	Q	K	N	P	G	D	I	E	G	W	I	M	L	G	R	V	G	M	A	L	G	N	A	S	I
Secondary structure
SS confidence
Disorder				?									?	?	?	?	?	?	?	?	?																	?		?																	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		A	T	D	A	Y	A	T	A	Y	R	L	D	P	K	N	S	D	A	A	L	G	Y	A	E	A	L	T	R	S	S	D	P	N	D	N	R	L	G	G	E	L	L	R	Q	L	V	R	T	D	H	S	N	I	R	V	L	S	M	Y	A
Secondary structure
SS confidence
Disorder																															?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350
Sequence		F	N	A	F	E	Q	Q	R	F	G	E	A	V	A	A	W	E	M	M	L	K	L	L	P	A	N	D	T	R	R	A	V	I	E	R	S	I	A	Q	A	M	Q	H	L	S	P	Q	E	S	K
Secondary structure
SS confidence
Disorder																									?																				?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3pe3 chain D Region: 185 - 349 Aligned: 162 Modelled: 165 Confidence: 99.9% Identity: 17% PDB header:transferase Chain: D: PDB Molecule:udp-n-acetylglucosamine--peptide n- PDBTitle: structure of human o-glcnac transferase and its complex with a peptide2 substrate Phyre2 PDB 2hl7 chain A Region: 15 - 96 Aligned: 82 Modelled: 82 Confidence: 99.9% Identity: 59% PDB header:oxidoreductase Chain: A: PDB Molecule:cytochrome c-type biogenesis protein ccmh; PDBTitle: crystal structure of the periplasmic domain of ccmh from pseudomonas2 aeruginosa Phyre2 PDB 2xpi chain A Region: 55 - 337 Aligned: 268 Modelled: 283 Confidence: 99.9% Identity: 11% PDB header:cell cycle Chain: A: PDB Molecule:anaphase-promoting complex subunit cut9; PDBTitle: crystal structure of apc/c hetero-tetramer cut9-hcn1 Phyre2 PDB 2e2e chain A Region: 206 - 348 Aligned: 142 Modelled: 143 Confidence: 99.9% Identity: 20% PDB header:lyase Chain: A: PDB Molecule:formate-dependent nitrite reductase complex nrfg subunit; PDBTitle: tpr domain of nrfg mediates the complex formation between heme lyase2 and formate-dependent nitrite reductase in escherichia coli o157:h7 Phyre2 PDB 2kw0 chain A Region: 19 - 99 Aligned: 81 Modelled: 81 Confidence: 99.9% Identity: 100% PDB header:oxidoreductase Chain: A: PDB Molecule:ccmh protein; PDBTitle: solution structure of n-terminal domain of ccmh from escherichia.coli Phyre2 PDB 1d8d chain A Region: 152 - 337 Aligned: 183 Modelled: 186 Confidence: 99.8% Identity: 14% Fold: alpha-alpha superhelix Superfamily: Protein prenylyltransferase Family: Protein prenylyltransferase Phyre2 PDB 2h6f chain A domain 1 Region: 152 - 337 Aligned: 183 Modelled: 186 Confidence: 99.8% Identity: 14% Fold: alpha-alpha superhelix Superfamily: Protein prenylyltransferase Family: Protein prenylyltransferase Phyre2 PDB 2y4t chain A Region: 153 - 343 Aligned: 191 Modelled: 191 Confidence: 99.8% Identity: 19% PDB header:chaperone Chain: A: PDB Molecule:dnaj homolog subfamily c member 3; PDBTitle: crystal structure of the human co-chaperone p58(ipk) Phyre2 PDB 1w3b chain A Region: 53 - 339 Aligned: 284 Modelled: 287 Confidence: 99.8% Identity: 11% Fold: alpha-alpha superhelix Superfamily: TPR-like Family: Tetratricopeptide repeat (TPR) Phyre2 PDB 1tno chain I Region: 152 - 337 Aligned: 183 Modelled: 186 Confidence: 99.8% Identity: 14% PDB header:transferase Chain: I: PDB Molecule:geranylgeranyltransferase type i alpha subunit; PDBTitle: rat protein geranylgeranyltransferase type-i complexed with2 a ggpp analog and a kkksktkcvim peptide derived from k-3 ras4b Phyre2 PDB 3ieg chain B Region: 155 - 350 Aligned: 192 Modelled: 196 Confidence: 99.8% Identity: 19% PDB header:chaperone Chain: B: PDB Molecule:dnaj homolog subfamily c member 3; PDBTitle: crystal structure of p58(ipk) tpr domain at 2.5 a Phyre2 PDB 3q75 chain A Region: 152 - 346 Aligned: 195 Modelled: 195 Confidence: 99.8% Identity: 10% PDB header:transferase Chain: A: PDB Molecule:farnesyltransferase alpha subunit; PDBTitle: cryptococcus neoformans protein farnesyltransferase in complex with2 fpt-ii and tkcvvm peptide Phyre2 PDB 1dce chain A domain 1 Region: 77 - 347 Aligned: 268 Modelled: 271 Confidence: 99.8% Identity: 7% Fold: alpha-alpha superhelix Superfamily: Protein prenylyltransferase Family: Protein prenylyltransferase Phyre2 PDB 3fp4 chain A Region: 143 - 346 Aligned: 204 Modelled: 204 Confidence: 99.8% Identity: 13% PDB header:transport protein Chain: A: PDB Molecule:tpr repeat-containing protein yhr117w; PDBTitle: crystal structure of tom71 complexed with ssa1 c-terminal2 fragment Phyre2 PDB 1xnf chain A Region: 152 - 342 Aligned: 191 Modelled: 191 Confidence: 99.8% Identity: 14% Fold: alpha-alpha superhelix Superfamily: TPR-like Family: Tetratricopeptide repeat (TPR) Phyre2 PDB 3urz chain B Region: 157 - 343 Aligned: 183 Modelled: 186 Confidence: 99.8% Identity: 12% PDB header:protein binding Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of a hypothetical protein (bacova_03105) from2 bacteroides ovatus atcc 8483 at 2.19 a resolution Phyre2 PDB 3as5 chain A Region: 155 - 335 Aligned: 178 Modelled: 181 Confidence: 99.8% Identity: 17% PDB header:protein binding Chain: A: PDB Molecule:mama; PDBTitle: mama amb-1 p212121 Phyre2 PDB 2q7f chain A Region: 142 - 334 Aligned: 190 Modelled: 193 Confidence: 99.8% Identity: 9% PDB header:protein binding Chain: A: PDB Molecule:yrrb protein; PDBTitle: crystal structure of yrrb: a tpr protein with an unusual peptide-2 binding site Phyre2 PDB 2hyz chain A Region: 189 - 326 Aligned: 135 Modelled: 138 Confidence: 99.8% Identity: 19% PDB header:de novo protein Chain: A: PDB Molecule:synthetic consensus tpr protein; PDBTitle: crystal structure of an 8 repeat consensus tpr superhelix2 (orthorombic crystal form) Phyre2 PDB 3hym chain B Region: 156 - 338 Aligned: 183 Modelled: 183 Confidence: 99.8% Identity: 21% PDB header:cell cycle, ligase Chain: B: PDB Molecule:cell division cycle protein 16 homolog; PDBTitle: insights into anaphase promoting complex tpr subdomain2 assembly from a cdc26-apc6 structure Phyre2 1 c3pe3D_ 2 c2hl7A_ 3 c2xpiA_ 4 c2e2eA_ 5 c2kw0A_ 6 d1d8da_ 7 d2h6fa1 8 c2y4tA_ 9 d1w3ba_ 10 c1tnoI_ 11 c3iegB_ 12 c3q75A_ 13 d1dcea1 14 c3fp4A_ 15 d1xnfa_ 16 c3urzB_ 17 c3as5A_ 18 c2q7fA_ 19 c2hyzA_ 20 c3hymB_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3pe3D_ 99.9 17 PDB header:transferase Chain: D: PDB Molecule:udp-n-acetylglucosamine--peptide n- PDBTitle: structure of human o-glcnac transferase and its complex with a peptide2 substrate 2 c2hl7A_ 99.9 59 PDB header:oxidoreductase Chain: A: PDB Molecule:cytochrome c-type biogenesis protein ccmh; PDBTitle: crystal structure of the periplasmic domain of ccmh from pseudomonas2 aeruginosa 3 c2xpiA_ 99.9 11 PDB header:cell cycle Chain: A: PDB Molecule:anaphase-promoting complex subunit cut9; PDBTitle: crystal structure of apc/c hetero-tetramer cut9-hcn1 4 c2e2eA_ 99.9 20 PDB header:lyase Chain: A: PDB Molecule:formate-dependent nitrite reductase complex nrfg subunit; PDBTitle: tpr domain of nrfg mediates the complex formation between heme lyase2 and formate-dependent nitrite reductase in escherichia coli o157:h7 5 c2kw0A_ 99.9 100 PDB header:oxidoreductase Chain: A: PDB Molecule:ccmh protein; PDBTitle: solution structure of n-terminal domain of ccmh from escherichia.coli 6 d1d8da_ 99.8 14 Fold:alpha-alpha superhelix Superfamily:Protein prenylyltransferase Family:Protein prenylyltransferase 7 d2h6fa1 99.8 14 Fold:alpha-alpha superhelix Superfamily:Protein prenylyltransferase Family:Protein prenylyltransferase 8 c2y4tA_ 99.8 19 PDB header:chaperone Chain: A: PDB Molecule:dnaj homolog subfamily c member 3; PDBTitle: crystal structure of the human co-chaperone p58(ipk) 9 d1w3ba_ 99.8 11 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 10 c1tnoI_ 99.8 14 PDB header:transferase Chain: I: PDB Molecule:geranylgeranyltransferase type i alpha subunit; PDBTitle: rat protein geranylgeranyltransferase type-i complexed with2 a ggpp analog and a kkksktkcvim peptide derived from k-3 ras4b 11 c3iegB_ 99.8 19 PDB header:chaperone Chain: B: PDB Molecule:dnaj homolog subfamily c member 3; PDBTitle: crystal structure of p58(ipk) tpr domain at 2.5 a 12 c3q75A_ 99.8 10 PDB header:transferase Chain: A: PDB Molecule:farnesyltransferase alpha subunit; PDBTitle: cryptococcus neoformans protein farnesyltransferase in complex with2 fpt-ii and tkcvvm peptide 13 d1dcea1 99.8 7 Fold:alpha-alpha superhelix Superfamily:Protein prenylyltransferase Family:Protein prenylyltransferase 14 c3fp4A_ 99.8 13 PDB header:transport protein Chain: A: PDB Molecule:tpr repeat-containing protein yhr117w; PDBTitle: crystal structure of tom71 complexed with ssa1 c-terminal2 fragment 15 d1xnfa_ 99.8 14 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 16 c3urzB_ 99.8 12 PDB header:protein binding Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of a hypothetical protein (bacova_03105) from2 bacteroides ovatus atcc 8483 at 2.19 a resolution 17 c3as5A_ 99.8 17 PDB header:protein binding Chain: A: PDB Molecule:mama; PDBTitle: mama amb-1 p212121 18 c2q7fA_ 99.8 9 PDB header:protein binding Chain: A: PDB Molecule:yrrb protein; PDBTitle: crystal structure of yrrb: a tpr protein with an unusual peptide-2 binding site 19 c2hyzA_ 99.8 19 PDB header:de novo protein Chain: A: PDB Molecule:synthetic consensus tpr protein; PDBTitle: crystal structure of an 8 repeat consensus tpr superhelix2 (orthorombic crystal form) 20 c3hymB_ 99.8 21 PDB header:cell cycle, ligase Chain: B: PDB Molecule:cell division cycle protein 16 homolog; PDBTitle: insights into anaphase promoting complex tpr subdomain2 assembly from a cdc26-apc6 structure 21 c3cvpA_ not modelled 99.8 21 PDB header:transport protein Chain: A: PDB Molecule:peroxisome targeting signal 1 receptor pex5; PDBTitle: structure of peroxisomal targeting signal 1 (pts1) binding2 domain of trypanosoma brucei peroxin 5 (tbpex5)complexed3 to pts1 peptide (10-skl) 22 c1fchB_ not modelled 99.7 14 PDB header:signaling protein Chain: B: PDB Molecule:peroxisomal targeting signal 1 receptor; PDBTitle: crystal structure of the pts1 complexed to the tpr region2 of human pex5 23 c1wao4_ not modelled 99.7 15 PDB header:hydrolase Chain: 4: PDB Molecule:serine/threonine protein phosphatase 5; PDBTitle: pp5 structure 24 d1fcha_ not modelled 99.7 18 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 25 c3draA_ not modelled 99.7 11 PDB header:transferase Chain: A: PDB Molecule:protein PDBTitle: candida albicans protein geranylgeranyltransferase-i2 complexed with ggpp 26 c2r5sB_ not modelled 99.7 14 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein vp0806; PDBTitle: the crystal structure of a domain of protein vp0806 (unknown function)2 from vibrio parahaemolyticus rimd 2210633 27 c2ho1B_ not modelled 99.7 18 PDB header:protein binding Chain: B: PDB Molecule:type 4 fimbrial biogenesis protein pilf; PDBTitle: functional characterization of pseudomonas aeruginosa pilf 28 d1hh8a_ not modelled 99.7 11 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 29 c2xcbA_ not modelled 99.7 14 PDB header:protein binding Chain: A: PDB Molecule:regulatory protein pcrh; PDBTitle: crystal structure of pcrh in complex with the chaperone2 binding region of popd 30 c3gyzB_ not modelled 99.7 8 PDB header:chaperone Chain: B: PDB Molecule:chaperone protein ipgc; PDBTitle: crystal structure of ipgc from shigella flexneri 31 c2vq2A_ not modelled 99.7 12 PDB header:structural protein Chain: A: PDB Molecule:putative fimbrial biogenesis and twitching PDBTitle: crystal structure of pilw, widely conserved type iv pilus2 biogenesis factor 32 d1elwa_ not modelled 99.7 21 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 33 c2vyiA_ not modelled 99.7 18 PDB header:chaperone Chain: A: PDB Molecule:sgta protein; PDBTitle: crystal structure of the tpr domain of human sgt 34 c2gw1A_ not modelled 99.7 15 PDB header:protein transport Chain: A: PDB Molecule:mitochondrial precursor proteins import receptor; PDBTitle: crystal structure of the yeast tom70 35 d2c2la1 not modelled 99.7 12 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 36 c2c2lD_ not modelled 99.7 14 PDB header:chaperone Chain: D: PDB Molecule:carboxy terminus of hsp70-interacting protein; PDBTitle: crystal structure of the chip u-box e3 ubiquitin ligase 37 d2buga1 not modelled 99.7 15 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 38 d1zu2a1 not modelled 99.7 20 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 39 c2pl2A_ not modelled 99.7 18 PDB header:protein binding Chain: A: PDB Molecule:hypothetical conserved protein ttc0263; PDBTitle: crystal structure of ttc0263: a thermophilic tpr protein in thermus2 thermophilus hb27 40 c3sz7A_ not modelled 99.6 17 PDB header:chaperone regulator Chain: A: PDB Molecule:hsc70 cochaperone (sgt); PDBTitle: crystal structure of the sgt2 tpr domain from aspergillus fumigatus 41 c3qdnA_ not modelled 99.6 13 PDB header:oxidoreductase Chain: A: PDB Molecule:putative thioredoxin protein; PDBTitle: putative thioredoxin protein from salmonella typhimurium 42 d1nzna_ not modelled 99.6 13 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 43 c2kckA_ not modelled 99.6 19 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:tpr repeat; PDBTitle: nmr solution structure of the northeast structural genomics2 consortium (nesg) target mrr121a 44 c3ly8A_ not modelled 99.6 11 PDB header:signaling protein Chain: A: PDB Molecule:transcriptional activator cadc; PDBTitle: crystal structure of mutant d471e of the periplasmic domain of cadc 45 c2dbaA_ not modelled 99.6 17 PDB header:structural protein Chain: A: PDB Molecule:smooth muscle cell associated protein-1, isoform PDBTitle: the solution structure of the tetratrico peptide repeat of2 human smooth muscle cell associated protein-1, isoform 2 46 c3mv3B_ not modelled 99.6 12 PDB header:protein transport Chain: B: PDB Molecule:coatomer subunit epsilon; PDBTitle: crystal structure of a-cop in complex with e-cop 47 d1a17a_ not modelled 99.6 15 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 48 c3q49B_ not modelled 99.6 14 PDB header:ligase/chaperone Chain: B: PDB Molecule:stip1 homology and u box-containing protein 1; PDBTitle: crystal structure of the tpr domain of chip complexed with hsp70-c2 peptide 49 d1iyga_ not modelled 99.6 14 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 50 c1ihgA_ not modelled 99.6 18 PDB header:isomerase Chain: A: PDB Molecule:cyclophilin 40; PDBTitle: bovine cyclophilin 40, monoclinic form 51 c2vsnB_ not modelled 99.6 14 PDB header:transferase Chain: B: PDB Molecule:xcogt; PDBTitle: structure and topological arrangement of an o-glcnac2 transferase homolog: insight into molecular control of3 intracellular glycosylation 52 d2ooea1 not modelled 99.6 8 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:HAT/Suf repeat 53 c3rkvA_ not modelled 99.6 18 PDB header:isomerase Chain: A: PDB Molecule:putative peptidylprolyl isomerase; PDBTitle: c-terminal domain of protein c56c10.10, a putative peptidylprolyl2 isomerase, from caenorhabditis elegans 54 d1p5qa1 not modelled 99.6 17 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 55 c1kt0A_ not modelled 99.6 14 PDB header:isomerase Chain: A: PDB Molecule:51 kda fk506-binding protein; PDBTitle: structure of the large fkbp-like protein, fkbp51, involved in steroid2 receptor complexes 56 c2uy1A_ not modelled 99.6 10 PDB header:rna-binding protein Chain: A: PDB Molecule:cleavage stimulation factor 77; PDBTitle: crystal structure of cstf-77 57 d1hxia_ not modelled 99.6 17 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 58 c3mkrA_ not modelled 99.5 9 PDB header:transport protein Chain: A: PDB Molecule:coatomer subunit epsilon; PDBTitle: crystal structure of yeast alpha/epsilon-cop subcomplex of the copi2 vesicular coat 59 d1pc2a_ not modelled 99.5 14 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 60 c2fbnA_ not modelled 99.5 14 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:70 kda peptidylprolyl isomerase, putative; PDBTitle: plasmodium falciparum putative fk506-binding protein2 pfl2275c, c-terminal tpr-containing domain 61 d2fbna1 not modelled 99.5 14 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 62 d1kt1a1 not modelled 99.5 18 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 63 c3beeB_ not modelled 99.5 25 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative yfre protein; PDBTitle: crystal structure of putative yfre protein from vibrio2 parahaemolyticus 64 c1qz2B_ not modelled 99.5 18 PDB header:isomerase/chaperone Chain: B: PDB Molecule:fk506-binding protein 4; PDBTitle: crystal structure of fkbp52 c-terminal domain complex with2 the c-terminal peptide meevd of hsp90 65 d1elra_ not modelled 99.5 15 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 66 d1ihga1 not modelled 99.5 16 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 67 c3gw4B_ not modelled 99.5 12 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of uncharacterized protein from deinococcus2 radiodurans. northeast structural genomics consortium target drr162b. 68 c2katA_ not modelled 99.5 14 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: solution structure of protein bpp2914 from bordetella2 parapertussis. northeast structural genomics consortium3 target bpr206 69 d1qsaa1 not modelled 99.5 14 Fold:alpha-alpha superhelix Superfamily:Bacterial muramidases Family:Bacterial muramidases 70 c1ltxA_ not modelled 99.5 12 PDB header:transferase/protein binding Chain: A: PDB Molecule:rab geranylgeranyltransferase alpha subunit; PDBTitle: structure of rab escort protein-1 in complex with rab2 geranylgeranyl transferase and isoprenoid 71 c2vgxA_ not modelled 99.4 15 PDB header:chaperone Chain: A: PDB Molecule:chaperone sycd; PDBTitle: structure of the yersinia enterocolitica type iii secretion2 translocator chaperone sycd 72 d1zbpa1 not modelled 99.4 9 Fold:ImpE-like Superfamily:ImpE-like Family:ImpE-like 73 c2xevB_ not modelled 99.4 13 PDB header:metal binding Chain: B: PDB Molecule:ybgf; PDBTitle: crystal structure of the tpr domain of xanthomonas2 campestris ybgf 74 c1na3A_ not modelled 99.4 24 PDB header:de novo protein Chain: A: PDB Molecule:designed protein ctpr2; PDBTitle: design of stable alpha-helical arrays from an idealized tpr2 motif 75 c3k9iA_ not modelled 99.4 17 PDB header:protein binding Chain: A: PDB Molecule:bh0479 protein; PDBTitle: crystal structure of putative protein binding protein (np_241345.1)2 from bacillus halodurans at 2.71 a resolution 76 d1hz4a_ not modelled 99.4 12 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Transcription factor MalT domain III 77 c2yhcA_ not modelled 99.4 14 PDB header:membrane protein Chain: A: PDB Molecule:upf0169 lipoprotein yfio; PDBTitle: structure of bamd from e. coli 78 c2if4A_ not modelled 99.4 15 PDB header:signaling protein Chain: A: PDB Molecule:atfkbp42; PDBTitle: crystal structure of a multi-domain immunophilin from2 arabidopsis thaliana 79 c2ifuA_ not modelled 99.3 8 PDB header:endocytosis/exocytosis Chain: A: PDB Molecule:gamma-snap; PDBTitle: crystal structure of a gamma-snap from danio rerio 80 c3sf4B_ not modelled 99.3 25 PDB header:signaling protein/protein binding Chain: B: PDB Molecule:g-protein-signaling modulator 2; PDBTitle: crystal structure of the complex between the conserved cell polarity2 proteins inscuteable and lgn 81 c3qkyA_ not modelled 99.3 13 PDB header:membrane protein Chain: A: PDB Molecule:outer membrane assembly lipoprotein yfio; PDBTitle: crystal structure of rhodothermus marinus bamd 82 d2hr2a1 not modelled 99.3 18 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:CT2138-like 83 d1y8ma1 not modelled 99.3 16 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 84 c2kcvA_ not modelled 99.3 15 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:tetratricopeptide repeat domain protein; PDBTitle: solution nmr structure of tetratricopeptide repeat domain2 protein sru_0103 from salinibacter ruber, northeast3 structural genomics consortium (nesg) target srr115c 85 c3ulqA_ not modelled 99.2 12 PDB header:gene regulation/transcription activator Chain: A: PDB Molecule:response regulator aspartate phosphatase f; PDBTitle: crystal structure of the anti-activator rapf complexed with the2 response regulator coma dna binding domain 86 d2onda1 not modelled 99.2 8 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:HAT/Suf repeat 87 d1qqea_ not modelled 99.2 12 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 88 c2l6jA_ not modelled 99.2 15 PDB header:protein binding Chain: A: PDB Molecule:tpr repeat-containing protein associated with hsp90; PDBTitle: tah1 complexed by meevd 89 c3q15A_ not modelled 99.1 11 PDB header:hydrolase/kinase Chain: A: PDB Molecule:response regulator aspartate phosphatase h; PDBTitle: crystal structure of raph complexed with spo0f 90 c2avpA_ not modelled 99.1 18 PDB header:de novo protein Chain: A: PDB Molecule:synthetic consensus tpr protein; PDBTitle: crystal structure of an 8 repeat consensus tpr superhelix 91 d2pqrb1 not modelled 99.1 17 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 92 d1tjca_ not modelled 99.1 18 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 93 c2kc7A_ not modelled 99.0 11 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:bfr218_protein; PDBTitle: solution nmr structure of bacteroides fragilis protein2 bf1650. northeast structural genomics consortium target3 bfr218 94 c3nf1A_ not modelled 98.9 21 PDB header:motor protein, transport protein Chain: A: PDB Molecule:kinesin light chain 1; PDBTitle: crystal structure of the tpr domain of kinesin light chain 1 95 c3ceqB_ not modelled 98.9 18 PDB header:motor protein, transport protein Chain: B: PDB Molecule:kinesin light chain 2; PDBTitle: the tpr domain of human kinesin light chain 2 (hklc2) 96 c3fflC_ not modelled 98.9 15 PDB header:cell cycle Chain: C: PDB Molecule:anaphase-promoting complex subunit 7; PDBTitle: crystal structure of the n-terminal domain of anaphase-2 promoting complex subunit 7 97 c1xi4D_ not modelled 98.7 12 PDB header:endocytosis/exocytosis Chain: D: PDB Molecule:clathrin heavy chain; PDBTitle: clathrin d6 coat 98 d2ff4a2 not modelled 98.7 12 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:BTAD-like 99 c3n71A_ not modelled 98.6 13 PDB header:transcription Chain: A: PDB Molecule:histone lysine methyltransferase smyd1; PDBTitle: crystal structure of cardiac specific histone methyltransferase smyd1 100 c3q3hA_ not modelled 98.6 5 PDB header:transferase Chain: A: PDB Molecule:hmw1c-like glycosyltransferase; PDBTitle: crystal structure of the actinobacillus pleuropneumoniae hmw1c2 glycosyltransferase in complex with udp-glc 101 c1slyA_ not modelled 98.4 10 PDB header:glycosyltransferase Chain: A: PDB Molecule:70-kda soluble lytic transglycosylase; PDBTitle: complex of the 70-kda soluble lytic transglycosylase with2 bulgecin a 102 c2qfcB_ not modelled 98.1 10 PDB header:transcription regulation Chain: B: PDB Molecule:plcr protein; PDBTitle: crystal structure of bacillus thuringiensis plcr complexed with papr 103 d1ouva_ not modelled 98.1 24 Fold:alpha-alpha superhelix Superfamily:HCP-like Family:HCP-like 104 c3mekA_ not modelled 98.0 6 PDB header:transferase Chain: A: PDB Molecule:set and mynd domain-containing protein 3; PDBTitle: crystal structure of human histone-lysine n-2 methyltransferase smyd3 in complex with s-adenosyl-l-3 methionine 105 c3qwvA_ not modelled 97.9 7 PDB header:transferase Chain: A: PDB Molecule:set and mynd domain-containing protein 2; PDBTitle: crystal structure of histone lysine methyltransferase smyd2 in complex2 with the cofactor product adohcy 106 c3oxgA_ not modelled 97.8 5 PDB header:transferase Chain: A: PDB Molecule:set and mynd domain-containing protein 3; PDBTitle: human lysine methyltransferase smyd3 in complex with adohcy (form iii) 107 c2lahA_ not modelled 97.8 9 PDB header:cell cycle, apoptosis Chain: A: PDB Molecule:mitotic checkpoint serine/threonine-protein kinase bub1; PDBTitle: solution nmr structure of mitotic checkpoint serine/threonine-protein2 kinase bub1 n-terminal domain from homo sapiens, northeast structural3 genomics consortium target hr5460a (methods development) 108 d1iipa1 not modelled 97.6 12 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 109 c2wviA_ not modelled 97.5 11 PDB header:transferase Chain: A: PDB Molecule:mitotic checkpoint serine/threonine-protein PDBTitle: crystal structure of the n-terminal domain of bubr1 110 c3txmA_ not modelled 97.5 13 PDB header:hydrolase, protein binding Chain: A: PDB Molecule:26s proteasome regulatory complex subunit p42b; PDBTitle: crystal structure of rpn6 from drosophila melanogaster, gd(3+) complex 111 c2xm6A_ not modelled 97.4 11 PDB header:unknown function Chain: A: PDB Molecule:protein corresponding to locus c5321 from cft073 e.coli PDBTitle: crystal structure of the protein corresponding to locus c5321 from2 cft073 e.coli strain 112 c3e4bD_ not modelled 97.3 9 PDB header:protein binding Chain: D: PDB Molecule:algk; PDBTitle: crystal structure of algk from pseudomonas fluorescens wcs374r 113 c2ff4B_ not modelled 96.3 15 PDB header:transcription Chain: B: PDB Molecule:probable regulatory protein embr; PDBTitle: mycobacterium tuberculosis embr in complex with low affinity2 phosphopeptide 114 c3mkqA_ not modelled 96.0 13 PDB header:transport protein Chain: A: PDB Molecule:coatomer beta'-subunit; PDBTitle: crystal structure of yeast alpha/betaprime-cop subcomplex of the copi2 vesicular coat 115 c3rjvA_ not modelled 96.0 19 PDB header:protein binding Chain: A: PDB Molecule:putative sel1 repeat protein; PDBTitle: crystal structure of a putative sel1 repeat protein (kpn_04481) from2 klebsiella pneumoniae subsp. pneumoniae at 1.65 a resolution 116 c2pziA_ not modelled 95.4 11 PDB header:transferase Chain: A: PDB Molecule:probable serine/threonine-protein kinase pkng; PDBTitle: crystal structure of protein kinase pkng from mycobacterium2 tuberculosis in complex with tetrahydrobenzothiophene ax20017 117 d1ya0a1 not modelled 95.3 9 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 118 c3mkqB_ not modelled 94.3 20 PDB header:transport protein Chain: B: PDB Molecule:coatomer subunit alpha; PDBTitle: crystal structure of yeast alpha/betaprime-cop subcomplex of the copi2 vesicular coat 119 c3eslA_ not modelled 93.8 7 PDB header:cell cycle Chain: A: PDB Molecule:checkpoint serine/threonine-protein kinase bub1; PDBTitle: crystal structure of the conserved n-terminal domain of the2 mitotic checkpoint component bub1 120 c3lvhA_ not modelled 93.2 16 PDB header:structural protein Chain: A: PDB Molecule:clathrin heavy chain 1; PDBTitle: crystal structure of a clathrin heavy chain and clathrin light chain2 complex

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0