Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	I	S	A	S	L	Q	Q	R	K	T	R	T	R	R	S	M	L	F	V	P	G	A	N	A	A	M	V	S	N	S	F	I	Y	P	A	D	A	L	M	F	D	L	E	D	S	V	A	L	R	E	K	D	T	A	R	R	M	V	Y
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		H	A	L	Q	H	P	L	Y	R	D	I	E	T	I	V	R	V	N	A	L	D	S	E	W	G	V	N	D	L	E	A	V	V	R	G	G	A	D	V	V	R	L	P	K	T	D	T	A	Q	D	V	L	D	I	E	K	E	I	L	R
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		I	E	K	A	C	G	R	E	P	G	S	T	G	L	L	A	A	I	E	S	P	L	G	I	T	R	A	V	E	I	A	H	A	S	E	R	L	I	G	I	A	L	G	A	E	D	Y	V	R	N	L	R	T	E	R	S	P	E	G	T
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		E	L	L	F	A	R	C	S	I	L	Q	A	A	R	S	A	G	I	Q	A	F	D	T	V	Y	S	D	A	N	N	E	A	G	F	L	Q	E	A	A	H	I	K	Q	L	G	F	D	G	K	S	L	I	N	P	R	Q	I	D	L	L
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		H	N	L	Y	A	P	T	Q	K	E	V	D	H	A	R	R	V	V	E	A	A	E	A	A	A	R	E	G	L	G	V	V	S	L	N	G	K	M	V	D	G	P	V	I	D	R	A	R	L	V	L	S	R	A	E	L	S	G	I	R
Secondary structure
SS confidence
Disorder																									?	?	?	?	?	?		?																										?	?	?	?
Disorder confidence
		.	.
Sequence		E	E
Secondary structure
SS confidence
Disorder		?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3r4i chain B Region: 9 - 300 Aligned: 287 Modelled: 289 Confidence: 100.0% Identity: 19% PDB header:lyase Chain: B: PDB Molecule:citrate lyase; PDBTitle: crystal structure of a citrate lyase (bxe_b2899) from burkholderia2 xenovorans lb400 at 2.24 a resolution Phyre2 PDB 3pug chain A Region: 7 - 298 Aligned: 292 Modelled: 292 Confidence: 100.0% Identity: 17% PDB header:transferase Chain: A: PDB Molecule:malate synthase; PDBTitle: haloferax volcanii malate synthase native at 3mm glyoxylate Phyre2 PDB 3qqw chain C Region: 12 - 300 Aligned: 266 Modelled: 266 Confidence: 100.0% Identity: 18% PDB header:lyase Chain: C: PDB Molecule:putative citrate lyase; PDBTitle: crystal structure of a hypothetical lyase (reut_b4148) from ralstonia2 eutropha jmp134 at 2.44 a resolution Phyre2 PDB 3cuz chain A Region: 7 - 302 Aligned: 295 Modelled: 296 Confidence: 100.0% Identity: 19% PDB header:transferase Chain: A: PDB Molecule:malate synthase a; PDBTitle: atomic resolution structures of escherichia coli and2 bacillis anthracis malate synthase a: comparison with3 isoform g and implications for structure based drug design Phyre2 PDB 3qll chain B Region: 15 - 251 Aligned: 207 Modelled: 237 Confidence: 100.0% Identity: 33% PDB header:lyase Chain: B: PDB Molecule:citrate lyase; PDBTitle: crystal structure of ripc from yersinia pestis Phyre2 PDB 1sgj chain B Region: 10 - 244 Aligned: 226 Modelled: 228 Confidence: 100.0% Identity: 31% PDB header:lyase Chain: B: PDB Molecule:citrate lyase, beta subunit; PDBTitle: crystal structure of citrate lyase beta subunit Phyre2 PDB 1sgj chain A Region: 10 - 244 Aligned: 226 Modelled: 228 Confidence: 100.0% Identity: 31% Fold: TIM beta/alpha-barrel Superfamily: Phosphoenolpyruvate/pyruvate domain Family: HpcH/HpaI aldolase Phyre2 PDB 1u5v chain A Region: 9 - 245 Aligned: 216 Modelled: 222 Confidence: 100.0% Identity: 31% PDB header:lyase Chain: A: PDB Molecule:cite; PDBTitle: structure of cite complexed with triphosphate group of atp2 form mycobacterium tuberculosis Phyre2 PDB 1u5h chain A Region: 9 - 245 Aligned: 216 Modelled: 222 Confidence: 100.0% Identity: 31% Fold: TIM beta/alpha-barrel Superfamily: Phosphoenolpyruvate/pyruvate domain Family: HpcH/HpaI aldolase Phyre2 PDB 3cux chain A Region: 7 - 302 Aligned: 295 Modelled: 296 Confidence: 100.0% Identity: 18% PDB header:transferase Chain: A: PDB Molecule:malate synthase; PDBTitle: atomic resolution structures of escherichia coli and2 bacillis anthracis malate synthase a: comparison with3 isoform g and implications for structure based drug design Phyre2 PDB 1dxe chain A Region: 1 - 244 Aligned: 223 Modelled: 242 Confidence: 100.0% Identity: 14% Fold: TIM beta/alpha-barrel Superfamily: Phosphoenolpyruvate/pyruvate domain Family: HpcH/HpaI aldolase Phyre2 PDB 2v5j chain B Region: 18 - 244 Aligned: 206 Modelled: 223 Confidence: 100.0% Identity: 18% PDB header:lyase Chain: B: PDB Molecule:2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; PDBTitle: apo class ii aldolase hpch Phyre2 PDB 2vwt chain A Region: 1 - 227 Aligned: 208 Modelled: 227 Confidence: 100.0% Identity: 22% PDB header:lyase Chain: A: PDB Molecule:yfau, 2-keto-3-deoxy sugar aldolase; PDBTitle: crystal structure of yfau, a metal ion dependent class ii2 aldolase from escherichia coli k12 - mg-pyruvate product3 complex Phyre2 PDB 1izc chain A Region: 6 - 262 Aligned: 234 Modelled: 257 Confidence: 100.0% Identity: 20% PDB header:lyase Chain: A: PDB Molecule:macrophomate synthase intermolecular diels-alderase; PDBTitle: crystal structure analysis of macrophomate synthase Phyre2 PDB 1izc chain A Region: 6 - 262 Aligned: 234 Modelled: 257 Confidence: 100.0% Identity: 20% Fold: TIM beta/alpha-barrel Superfamily: Phosphoenolpyruvate/pyruvate domain Family: HpcH/HpaI aldolase Phyre2 PDB 3qz6 chain A Region: 22 - 217 Aligned: 185 Modelled: 192 Confidence: 100.0% Identity: 16% PDB header:lyase Chain: A: PDB Molecule:hpch/hpai aldolase; PDBTitle: the crystal structure of hpch/hpai aldolase from desulfitobacterium2 hafniense dcb-2 Phyre2 PDB 1e0t chain A domain 2 Region: 13 - 297 Aligned: 219 Modelled: 246 Confidence: 99.9% Identity: 16% Fold: TIM beta/alpha-barrel Superfamily: Phosphoenolpyruvate/pyruvate domain Family: Pyruvate kinase Phyre2 PDB 1n8i chain A Region: 36 - 302 Aligned: 267 Modelled: 267 Confidence: 99.9% Identity: 19% Fold: TIM beta/alpha-barrel Superfamily: Malate synthase G Family: Malate synthase G Phyre2 PDB 1a3x chain A domain 2 Region: 8 - 255 Aligned: 231 Modelled: 241 Confidence: 99.9% Identity: 16% Fold: TIM beta/alpha-barrel Superfamily: Phosphoenolpyruvate/pyruvate domain Family: Pyruvate kinase Phyre2 PDB 1d8c chain A Region: 38 - 302 Aligned: 265 Modelled: 265 Confidence: 99.9% Identity: 21% Fold: TIM beta/alpha-barrel Superfamily: Malate synthase G Family: Malate synthase G Phyre2 1 c3r4iB_ 2 c3pugA_ 3 c3qqwC_ 4 c3cuzA_ 5 c3qllB_ 6 c1sgjB_ 7 d1sgja_ 8 c1u5vA_ 9 d1u5ha_ 10 c3cuxA_ 11 d1dxea_ 12 c2v5jB_ 13 c2vwtA_ 14 c1izcA_ 15 d1izca_ 16 c3qz6A_ 17 d1e0ta2 18 d1n8ia_ 19 d1a3xa2 20 d1d8ca_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3r4iB_ 100.0 19 PDB header:lyase Chain: B: PDB Molecule:citrate lyase; PDBTitle: crystal structure of a citrate lyase (bxe_b2899) from burkholderia2 xenovorans lb400 at 2.24 a resolution 2 c3pugA_ 100.0 17 PDB header:transferase Chain: A: PDB Molecule:malate synthase; PDBTitle: haloferax volcanii malate synthase native at 3mm glyoxylate 3 c3qqwC_ 100.0 18 PDB header:lyase Chain: C: PDB Molecule:putative citrate lyase; PDBTitle: crystal structure of a hypothetical lyase (reut_b4148) from ralstonia2 eutropha jmp134 at 2.44 a resolution 4 c3cuzA_ 100.0 19 PDB header:transferase Chain: A: PDB Molecule:malate synthase a; PDBTitle: atomic resolution structures of escherichia coli and2 bacillis anthracis malate synthase a: comparison with3 isoform g and implications for structure based drug design 5 c3qllB_ 100.0 33 PDB header:lyase Chain: B: PDB Molecule:citrate lyase; PDBTitle: crystal structure of ripc from yersinia pestis 6 c1sgjB_ 100.0 31 PDB header:lyase Chain: B: PDB Molecule:citrate lyase, beta subunit; PDBTitle: crystal structure of citrate lyase beta subunit 7 d1sgja_ 100.0 31 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:HpcH/HpaI aldolase 8 c1u5vA_ 100.0 31 PDB header:lyase Chain: A: PDB Molecule:cite; PDBTitle: structure of cite complexed with triphosphate group of atp2 form mycobacterium tuberculosis 9 d1u5ha_ 100.0 31 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:HpcH/HpaI aldolase 10 c3cuxA_ 100.0 18 PDB header:transferase Chain: A: PDB Molecule:malate synthase; PDBTitle: atomic resolution structures of escherichia coli and2 bacillis anthracis malate synthase a: comparison with3 isoform g and implications for structure based drug design 11 d1dxea_ 100.0 14 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:HpcH/HpaI aldolase 12 c2v5jB_ 100.0 18 PDB header:lyase Chain: B: PDB Molecule:2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; PDBTitle: apo class ii aldolase hpch 13 c2vwtA_ 100.0 22 PDB header:lyase Chain: A: PDB Molecule:yfau, 2-keto-3-deoxy sugar aldolase; PDBTitle: crystal structure of yfau, a metal ion dependent class ii2 aldolase from escherichia coli k12 - mg-pyruvate product3 complex 14 c1izcA_ 100.0 20 PDB header:lyase Chain: A: PDB Molecule:macrophomate synthase intermolecular diels-alderase; PDBTitle: crystal structure analysis of macrophomate synthase 15 d1izca_ 100.0 20 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:HpcH/HpaI aldolase 16 c3qz6A_ 100.0 16 PDB header:lyase Chain: A: PDB Molecule:hpch/hpai aldolase; PDBTitle: the crystal structure of hpch/hpai aldolase from desulfitobacterium2 hafniense dcb-2 17 d1e0ta2 99.9 16 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Pyruvate kinase 18 d1n8ia_ 99.9 19 Fold:TIM beta/alpha-barrel Superfamily:Malate synthase G Family:Malate synthase G 19 d1a3xa2 99.9 16 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Pyruvate kinase 20 d1d8ca_ 99.9 21 Fold:TIM beta/alpha-barrel Superfamily:Malate synthase G Family:Malate synthase G 21 d1pkla2 not modelled 99.9 16 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Pyruvate kinase 22 d1liua2 not modelled 99.8 20 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Pyruvate kinase 23 d2g50a2 not modelled 99.8 19 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Pyruvate kinase 24 d1h6za1 not modelled 99.5 15 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Pyruvate phosphate dikinase, C-terminal domain 25 c2hwgA_ not modelled 99.5 19 PDB header:transferase Chain: A: PDB Molecule:phosphoenolpyruvate-protein phosphotransferase; PDBTitle: structure of phosphorylated enzyme i of the2 phosphoenolpyruvate:sugar phosphotransferase system 26 c2hroA_ not modelled 99.5 16 PDB header:transferase Chain: A: PDB Molecule:phosphoenolpyruvate-protein phosphotransferase; PDBTitle: structure of the full-lenght enzyme i of the pts system from2 staphylococcus carnosus 27 c2vgbB_ not modelled 99.5 21 PDB header:transferase Chain: B: PDB Molecule:pyruvate kinase isozymes r/l; PDBTitle: human erythrocyte pyruvate kinase 28 c3khdC_ not modelled 99.4 17 PDB header:transferase Chain: C: PDB Molecule:pyruvate kinase; PDBTitle: crystal structure of pff1300w. 29 c2bg5C_ not modelled 99.4 19 PDB header:transferase Chain: C: PDB Molecule:phosphoenolpyruvate-protein kinase; PDBTitle: crystal structure of the phosphoenolpyruvate-binding enzyme2 i-domain from the thermoanaerobacter tengcongensis pep:3 sugar phosphotransferase system (pts) 30 d1vbga1 not modelled 99.4 15 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Pyruvate phosphate dikinase, C-terminal domain 31 d1kbla1 not modelled 99.4 17 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Pyruvate phosphate dikinase, C-terminal domain 32 c1e0tD_ not modelled 99.4 23 PDB header:phosphotransferase Chain: D: PDB Molecule:pyruvate kinase; PDBTitle: r292d mutant of e. coli pyruvate kinase 33 c1h6zA_ not modelled 99.4 15 PDB header:transferase Chain: A: PDB Molecule:pyruvate phosphate dikinase; PDBTitle: 3.0 a resolution crystal structure of glycosomal pyruvate2 phosphate dikinase from trypanosoma brucei 34 c1pklB_ not modelled 99.3 21 PDB header:transferase Chain: B: PDB Molecule:protein (pyruvate kinase); PDBTitle: the structure of leishmania pyruvate kinase 35 c1a3wB_ not modelled 99.3 23 PDB header:transferase Chain: B: PDB Molecule:pyruvate kinase; PDBTitle: pyruvate kinase from saccharomyces cerevisiae complexed with fbp, pg,2 mn2+ and k+ 36 c3e0vB_ not modelled 99.3 21 PDB header:transferase Chain: B: PDB Molecule:pyruvate kinase; PDBTitle: crystal structure of pyruvate kinase from leishmania mexicana in2 complex with sulphate ions 37 c1t5aB_ not modelled 99.3 25 PDB header:transferase Chain: B: PDB Molecule:pyruvate kinase, m2 isozyme; PDBTitle: human pyruvate kinase m2 38 c1kblA_ not modelled 99.3 18 PDB header:transferase Chain: A: PDB Molecule:pyruvate phosphate dikinase; PDBTitle: pyruvate phosphate dikinase 39 c1aqfB_ not modelled 99.3 26 PDB header:transferase Chain: B: PDB Molecule:pyruvate kinase; PDBTitle: pyruvate kinase from rabbit muscle with mg, k, and l-2 phospholactate 40 c2e28A_ not modelled 99.3 21 PDB header:transferase Chain: A: PDB Molecule:pyruvate kinase; PDBTitle: crystal structure analysis of pyruvate kinase from bacillus2 stearothermophilus 41 c3t07D_ not modelled 99.3 21 PDB header:transferase/transferase inhibitor Chain: D: PDB Molecule:pyruvate kinase; PDBTitle: crystal structure of s. aureus pyruvate kinase in complex with a2 naturally occurring bis-indole alkaloid 42 c3ma8A_ not modelled 99.3 19 PDB header:transferase Chain: A: PDB Molecule:pyruvate kinase; PDBTitle: crystal structure of cgd1_2040, a pyruvate kinase from cryptosporidium2 parvum 43 c1vbhA_ not modelled 99.2 18 PDB header:transferase Chain: A: PDB Molecule:pyruvate,orthophosphate dikinase; PDBTitle: pyruvate phosphate dikinase with bound mg-pep from maize 44 c3eoeC_ not modelled 99.2 21 PDB header:transferase Chain: C: PDB Molecule:pyruvate kinase; PDBTitle: crystal structure of pyruvate kinase from toxoplasma gondii, 55.m00007 45 c2olsA_ not modelled 99.1 17 PDB header:transferase Chain: A: PDB Molecule:phosphoenolpyruvate synthase; PDBTitle: the crystal structure of the phosphoenolpyruvate synthase from2 neisseria meningitidis 46 c3odmE_ not modelled 98.5 12 PDB header:lyase Chain: E: PDB Molecule:phosphoenolpyruvate carboxylase; PDBTitle: archaeal-type phosphoenolpyruvate carboxylase 47 c3fa4D_ not modelled 96.5 22 PDB header:lyase Chain: D: PDB Molecule:2,3-dimethylmalate lyase; PDBTitle: crystal structure of 2,3-dimethylmalate lyase, a pep mutase/isocitrate2 lyase superfamily member, triclinic crystal form 48 c3b8iF_ not modelled 96.4 18 PDB header:lyase Chain: F: PDB Molecule:pa4872 oxaloacetate decarboxylase; PDBTitle: crystal structure of oxaloacetate decarboxylase from pseudomonas2 aeruginosa (pa4872) in complex with oxalate and mg2+. 49 d1ujqa_ not modelled 96.3 21 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Phosphoenolpyruvate mutase/Isocitrate lyase-like 50 d1jqna_ not modelled 96.2 13 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Phosphoenolpyruvate carboxylase 51 c3eooL_ not modelled 96.0 15 PDB header:lyase Chain: L: PDB Molecule:methylisocitrate lyase; PDBTitle: 2.9a crystal structure of methyl-isocitrate lyase from2 burkholderia pseudomallei 52 c1jqoA_ not modelled 95.6 15 PDB header:lyase Chain: A: PDB Molecule:phosphoenolpyruvate carboxylase; PDBTitle: crystal structure of c4-form phosphoenolpyruvate carboxylase from2 maize 53 d1jqoa_ not modelled 95.6 15 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Phosphoenolpyruvate carboxylase 54 d1muma_ not modelled 94.9 18 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Phosphoenolpyruvate mutase/Isocitrate lyase-like 55 c1zlpA_ not modelled 94.8 15 PDB header:lyase Chain: A: PDB Molecule:petal death protein; PDBTitle: petal death protein psr132 with cysteine-linked glutaraldehyde forming2 a thiohemiacetal adduct 56 c2ze3A_ not modelled 94.3 21 PDB header:isomerase Chain: A: PDB Molecule:dfa0005; PDBTitle: crystal structure of dfa0005 complexed with alpha-ketoglutarate: a2 novel member of the icl/pepm superfamily from alkali-tolerant3 deinococcus ficus 57 d1s2wa_ not modelled 94.0 13 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Phosphoenolpyruvate mutase/Isocitrate lyase-like 58 c2qiwA_ not modelled 93.1 17 PDB header:transferase Chain: A: PDB Molecule:pep phosphonomutase; PDBTitle: crystal structure of a putative phosphoenolpyruvate phosphonomutase2 (ncgl1015, cgl1060) from corynebacterium glutamicum atcc 13032 at3 1.80 a resolution 59 c3lyeA_ not modelled 92.1 19 PDB header:hydrolase Chain: A: PDB Molecule:oxaloacetate acetyl hydrolase; PDBTitle: crystal structure of oxaloacetate acetylhydrolase 60 c3thaB_ not modelled 91.7 18 PDB header:lyase Chain: B: PDB Molecule:tryptophan synthase alpha chain; PDBTitle: tryptophan synthase subunit alpha from campylobacter jejuni. 61 c3ih1A_ not modelled 90.7 10 PDB header:lyase Chain: A: PDB Molecule:methylisocitrate lyase; PDBTitle: crystal structure of carboxyvinyl-carboxyphosphonate phosphorylmutase2 from bacillus anthracis 62 c2bdqA_ not modelled 90.5 13 PDB header:metal transport Chain: A: PDB Molecule:copper homeostasis protein cutc; PDBTitle: crystal structure of the putative copper homeostasis2 protein cutc from streptococcus agalactiae, northeast3 strucural genomics target sar15. 63 c2hjpA_ not modelled 88.1 23 PDB header:hydrolase Chain: A: PDB Molecule:phosphonopyruvate hydrolase; PDBTitle: crystal structure of phosphonopyruvate hydrolase complex with2 phosphonopyruvate and mg++ 64 d1h1ya_ not modelled 87.2 11 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:D-ribulose-5-phosphate 3-epimerase 65 d1lssa_ not modelled 86.9 18 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Potassium channel NAD-binding domain 66 d1qopa_ not modelled 81.1 14 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 67 d1piia2 not modelled 79.8 17 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 68 d1zfja1 not modelled 76.6 16 Fold:TIM beta/alpha-barrel Superfamily:Inosine monophosphate dehydrogenase (IMPDH) Family:Inosine monophosphate dehydrogenase (IMPDH) 69 c2c3zA_ not modelled 76.3 20 PDB header:lyase Chain: A: PDB Molecule:indole-3-glycerol phosphate synthase; PDBTitle: crystal structure of a truncated variant of indole-3-2 glycerol phosphate synthase from sulfolobus solfataricus 70 d2hmva1 not modelled 75.5 10 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Potassium channel NAD-binding domain 71 d1tqja_ not modelled 75.1 10 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:D-ribulose-5-phosphate 3-epimerase 72 d1rd5a_ not modelled 73.7 15 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 73 d1o4ua1 not modelled 71.7 19 Fold:TIM beta/alpha-barrel Superfamily:Nicotinate/Quinolinate PRTase C-terminal domain-like Family:NadC C-terminal domain-like 74 d2flia1 not modelled 70.8 13 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:D-ribulose-5-phosphate 3-epimerase 75 c3gndC_ not modelled 69.1 8 PDB header:lyase Chain: C: PDB Molecule:aldolase lsrf; PDBTitle: crystal structure of e. coli lsrf in complex with ribulose-5-phosphate 76 d1j5ta_ not modelled 69.0 18 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 77 c3llvA_ not modelled 67.8 18 PDB header:nad(p) binding protein Chain: A: PDB Molecule:exopolyphosphatase-related protein; PDBTitle: the crystal structure of the nad(p)-binding domain of an2 exopolyphosphatase-related protein from archaeoglobus fulgidus to3 1.7a 78 d1i4na_ not modelled 66.3 17 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 79 d1tqxa_ not modelled 66.0 8 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:D-ribulose-5-phosphate 3-epimerase 80 d1twda_ not modelled 65.9 14 Fold:TIM beta/alpha-barrel Superfamily:CutC-like Family:CutC-like 81 c3navB_ not modelled 63.6 15 PDB header:lyase Chain: B: PDB Molecule:tryptophan synthase alpha chain; PDBTitle: crystal structure of an alpha subunit of tryptophan synthase from2 vibrio cholerae o1 biovar el tor str. n16961 82 c3ct7E_ not modelled 60.8 12 PDB header:isomerase Chain: E: PDB Molecule:d-allulose-6-phosphate 3-epimerase; PDBTitle: crystal structure of d-allulose 6-phosphate 3-epimerase2 from escherichia coli k-12 83 c1e1cA_ not modelled 59.7 15 PDB header:isomerase Chain: A: PDB Molecule:methylmalonyl-coa mutase alpha chain; PDBTitle: methylmalonyl-coa mutase h244a mutant 84 c3ez4B_ not modelled 58.3 18 PDB header:transferase Chain: B: PDB Molecule:3-methyl-2-oxobutanoate hydroxymethyltransferase; PDBTitle: crystal structure of 3-methyl-2-oxobutanoate2 hydroxymethyltransferase from burkholderia pseudomallei 85 d1vrda1 not modelled 57.8 20 Fold:TIM beta/alpha-barrel Superfamily:Inosine monophosphate dehydrogenase (IMPDH) Family:Inosine monophosphate dehydrogenase (IMPDH) 86 d1id1a_ not modelled 57.5 12 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Potassium channel NAD-binding domain 87 c3s5oA_ not modelled 54.5 8 PDB header:lyase Chain: A: PDB Molecule:4-hydroxy-2-oxoglutarate aldolase, mitochondrial; PDBTitle: crystal structure of human 4-hydroxy-2-oxoglutarate aldolase bound to2 pyruvate 88 c3lciA_ not modelled 52.1 17 PDB header:lyase Chain: A: PDB Molecule:n-acetylneuraminate lyase; PDBTitle: the d-sialic acid aldolase mutant v251w 89 d1vc4a_ not modelled 51.4 18 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 90 c2rfgB_ not modelled 51.3 14 PDB header:lyase Chain: B: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from hahella2 chejuensis at 1.5a resolution 91 c2r8wB_ not modelled 47.8 17 PDB header:lyase Chain: B: PDB Molecule:agr_c_1641p; PDBTitle: the crystal structure of dihydrodipicolinate synthase (atu0899) from2 agrobacterium tumefaciens str. c58 92 c3pueA_ not modelled 47.8 14 PDB header:lyase Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of the complex of dhydrodipicolinate synthase from2 acinetobacter baumannii with lysine at 2.6a resolution 93 c2vc6A_ not modelled 46.9 10 PDB header:lyase Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: structure of mosa from s. meliloti with pyruvate bound 94 d1hl2a_ not modelled 46.5 17 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 95 c3o63B_ not modelled 46.5 14 PDB header:transferase Chain: B: PDB Molecule:probable thiamine-phosphate pyrophosphorylase; PDBTitle: crystal structure of thiamin phosphate synthase from mycobacterium2 tuberculosis 96 c3cprB_ not modelled 46.1 14 PDB header:lyase Chain: B: PDB Molecule:dihydrodipicolinate synthetase; PDBTitle: the crystal structure of corynebacterium glutamicum2 dihydrodipicolinate synthase to 2.2 a resolution 97 c3bicA_ not modelled 45.9 13 PDB header:isomerase Chain: A: PDB Molecule:methylmalonyl-coa mutase, mitochondrial precursor; PDBTitle: crystal structure of human methylmalonyl-coa mutase 98 c1zfjA_ not modelled 45.5 17 PDB header:oxidoreductase Chain: A: PDB Molecule:inosine monophosphate dehydrogenase; PDBTitle: inosine monophosphate dehydrogenase (impdh; ec 1.1.1.205) from2 streptococcus pyogenes 99 c2ekcA_ not modelled 44.2 10 PDB header:lyase Chain: A: PDB Molecule:tryptophan synthase alpha chain; PDBTitle: structural study of project id aq_1548 from aquifex aeolicus vf5 100 c3noeA_ not modelled 42.5 18 PDB header:lyase Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from pseudomonas2 aeruginosa 101 c2v9dB_ not modelled 42.2 13 PDB header:lyase Chain: B: PDB Molecule:yage; PDBTitle: crystal structure of yage, a prophage protein belonging to2 the dihydrodipicolinic acid synthase family from e. coli3 k12 102 c3fwzA_ not modelled 41.4 19 PDB header:membrane protein Chain: A: PDB Molecule:inner membrane protein ybal; PDBTitle: crystal structure of trka-n domain of inner membrane protein ybal from2 escherichia coli 103 d2a6na1 not modelled 40.7 8 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 104 c2ehhE_ not modelled 39.9 12 PDB header:lyase Chain: E: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from2 aquifex aeolicus 105 c3qc3B_ not modelled 39.6 15 PDB header:isomerase Chain: B: PDB Molecule:d-ribulose-5-phosphate-3-epimerase; PDBTitle: crystal structure of a d-ribulose-5-phosphate-3-epimerase (np_954699)2 from homo sapiens at 2.20 a resolution 106 c3g0sA_ not modelled 39.5 8 PDB header:lyase Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: dihydrodipicolinate synthase from salmonella typhimurium lt2 107 d1xkya1 not modelled 39.4 10 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 108 d2fy8a1 not modelled 38.0 18 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Potassium channel NAD-binding domain 109 c3qfeB_ not modelled 37.7 12 PDB header:lyase Chain: B: PDB Molecule:putative dihydrodipicolinate synthase family protein; PDBTitle: crystal structures of a putative dihydrodipicolinate synthase family2 protein from coccidioides immitis 110 d1xcfa_ not modelled 36.7 12 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 111 c2g1uA_ not modelled 35.6 12 PDB header:transport protein Chain: A: PDB Molecule:hypothetical protein tm1088a; PDBTitle: crystal structure of a putative transport protein (tm1088a) from2 thermotoga maritima at 1.50 a resolution 112 c3l4bG_ not modelled 35.4 14 PDB header:transport protein Chain: G: PDB Molecule:trka k+ channel protien tm1088b; PDBTitle: crystal structure of an octomeric two-subunit trka k+ channel ring2 gating assembly, tm1088a:tm1088b, from thermotoga maritima 113 d1geqa_ not modelled 34.2 10 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 114 c3fkkA_ not modelled 33.9 14 PDB header:lyase Chain: A: PDB Molecule:l-2-keto-3-deoxyarabonate dehydratase; PDBTitle: structure of l-2-keto-3-deoxyarabonate dehydratase 115 c2w91A_ not modelled 33.7 23 PDB header:hydrolase Chain: A: PDB Molecule:endo-beta-n-acetylglucosaminidase d; PDBTitle: structure of a streptococcus pneumoniae family 85 glycoside2 hydrolase, endo-d. 116 c3eywA_ not modelled 32.8 9 PDB header:transport protein Chain: A: PDB Molecule:c-terminal domain of glutathione-regulated potassium-efflux PDBTitle: crystal structure of the c-terminal domain of e. coli kefc in complex2 with keff 117 c3inpA_ not modelled 32.3 14 PDB header:isomerase Chain: A: PDB Molecule:d-ribulose-phosphate 3-epimerase; PDBTitle: 2.05 angstrom resolution crystal structure of d-ribulose-phosphate 3-2 epimerase from francisella tularensis. 118 c3fhaD_ not modelled 31.7 20 PDB header:hydrolase Chain: D: PDB Molecule:endo-beta-n-acetylglucosaminidase; PDBTitle: structure of endo-beta-n-acetylglucosaminidase a 119 c3gdbA_ not modelled 31.7 23 PDB header:hydrolase Chain: A: PDB Molecule:putative uncharacterized protein spr0440; PDBTitle: crystal structure of spr0440 glycoside hydrolase domain,2 endo-d from streptococcus pneumoniae r6 120 c2qjhH_ not modelled 31.2 22 PDB header:lyase Chain: H: PDB Molecule:putative aldolase mj0400; PDBTitle: m. jannaschii adh synthase covalently bound to2 dihydroxyacetone phosphate

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0