Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	L	A	G	K	K	I	V	L	G	V	S	G	G	I	A	A	Y	K	T	P	E	L	V	R	R	L	R	D	R	G	A	D	V	R	V	A	M	T	E	A	A	K	A	F	I	T	P	L	S	L	Q	A	V	S	G	Y	P	V
Secondary structure
SS confidence
Disorder		?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		S	D	S	L	L	D	P	A	A	E	A	A	M	G	H	I	E	L	G	K	W	A	D	L	V	I	L	A	P	A	T	A	D	L	I	A	R	V	A	A	G	M	A	N	D	L	V	S	T	I	C	L	A	T	P	A	P	V	A	V
Secondary structure
SS confidence
Disorder								?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		L	P	A	M	N	Q	Q	M	Y	R	A	A	A	T	Q	H	N	L	E	V	L	A	S	R	G	L	L	I	W	G	P	D	S	G	S	Q	A	C	G	D	I	G	P	G	R	M	L	D	P	L	T	I	V	D	M	A	V	A	H	F
Secondary structure
SS confidence
Disorder																																				?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		S	P	V	N	D	L	K	H	L	N	I	M	I	T	A	G	P	T	R	E	P	L	D	P	V	R	Y	I	S	N	H	S	S	G	K	M	G	F	A	I	A	A	A	A	A	R	R	G	A	N	V	T	L	V	S	G	P	V	S	L
Secondary structure
SS confidence
Disorder								?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		P	T	P	P	F	V	K	R	V	D	V	M	T	A	L	E	M	E	A	A	V	N	A	S	V	Q	Q	Q	N	I	F	I	G	C	A	A	V	A	D	Y	R	A	A	T	V	A	P	E	K	I	K	K	Q	A	T	Q	G	D	E	L
Secondary structure
SS confidence
Disorder																																														?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		T	I	K	M	V	K	N	P	D	I	V	A	G	V	A	A	L	K	D	H	R	P	Y	V	V	G	F	A	A	E	T	N	N	V	E	E	Y	A	R	Q	K	R	I	R	K	N	L	D	L	I	C	A	N	D	V	S	Q	P	T	Q
Secondary structure
SS confidence
Disorder																																																										?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.
Sequence		G	F	N	S	D	N	N	A	L	H	L	F	W	Q	D	G	D	K	V	L	P	L	E	R	K	E	L	L	G	Q	L	L	L	D	E	I	V	T	R	Y	D	E	K	N	R	R
Secondary structure
SS confidence
Disorder		?	?															?					?	?																			?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1u7z chain A Region: 184 - 405 Aligned: 215 Modelled: 222 Confidence: 100.0% Identity: 99% Fold: Ribokinase-like Superfamily: CoaB-like Family: CoaB-like Phyre2 PDB 2gk4 chain A Region: 190 - 400 Aligned: 201 Modelled: 211 Confidence: 100.0% Identity: 27% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:conserved hypothetical protein; PDBTitle: the crystal structure of the dna/pantothenate metabolism flavoprotein2 from streptococcus pneumoniae Phyre2 PDB 1p9o chain A Region: 174 - 402 Aligned: 206 Modelled: 214 Confidence: 100.0% Identity: 21% Fold: Ribokinase-like Superfamily: CoaB-like Family: CoaB-like Phyre2 PDB 1g5q chain A Region: 3 - 177 Aligned: 169 Modelled: 175 Confidence: 100.0% Identity: 19% Fold: Homo-oligomeric flavin-containing Cys decarboxylases, HFCD Superfamily: Homo-oligomeric flavin-containing Cys decarboxylases, HFCD Family: Homo-oligomeric flavin-containing Cys decarboxylases, HFCD Phyre2 PDB 1p3y chain 1 Region: 3 - 167 Aligned: 162 Modelled: 165 Confidence: 100.0% Identity: 26% Fold: Homo-oligomeric flavin-containing Cys decarboxylases, HFCD Superfamily: Homo-oligomeric flavin-containing Cys decarboxylases, HFCD Family: Homo-oligomeric flavin-containing Cys decarboxylases, HFCD Phyre2 PDB 3qjg chain D Region: 6 - 176 Aligned: 166 Modelled: 171 Confidence: 100.0% Identity: 20% PDB header:oxidoreductase Chain: D: PDB Molecule:epidermin biosynthesis protein epid; PDBTitle: epidermin biosynthesis protein epid from staphylococcus aureus Phyre2 PDB 1mvl chain A Region: 6 - 183 Aligned: 168 Modelled: 178 Confidence: 100.0% Identity: 28% PDB header:lyase Chain: A: PDB Molecule:ppc decarboxylase athal3a; PDBTitle: ppc decarboxylase mutant c175s Phyre2 PDB 1mvl chain A Region: 6 - 183 Aligned: 168 Modelled: 178 Confidence: 100.0% Identity: 28% Fold: Homo-oligomeric flavin-containing Cys decarboxylases, HFCD Superfamily: Homo-oligomeric flavin-containing Cys decarboxylases, HFCD Family: Homo-oligomeric flavin-containing Cys decarboxylases, HFCD Phyre2 PDB 3mcu chain F Region: 2 - 184 Aligned: 170 Modelled: 182 Confidence: 100.0% Identity: 19% PDB header:oxidoreductase Chain: F: PDB Molecule:dipicolinate synthase, b chain; PDBTitle: crystal structure of the dipicolinate synthase chain b from2 bacillus cereus. northeast structural genomics consortium3 target bcr215. Phyre2 PDB 3lqk chain A Region: 2 - 184 Aligned: 179 Modelled: 183 Confidence: 100.0% Identity: 16% PDB header:oxidoreductase Chain: A: PDB Molecule:dipicolinate synthase subunit b; PDBTitle: crystal structure of dipicolinate synthase subunit b from bacillus2 halodurans c Phyre2 PDB 1qzu chain A Region: 4 - 152 Aligned: 147 Modelled: 149 Confidence: 100.0% Identity: 29% Fold: Homo-oligomeric flavin-containing Cys decarboxylases, HFCD Superfamily: Homo-oligomeric flavin-containing Cys decarboxylases, HFCD Family: Homo-oligomeric flavin-containing Cys decarboxylases, HFCD Phyre2 PDB 1sbz chain A Region: 6 - 190 Aligned: 175 Modelled: 180 Confidence: 100.0% Identity: 19% Fold: Homo-oligomeric flavin-containing Cys decarboxylases, HFCD Superfamily: Homo-oligomeric flavin-containing Cys decarboxylases, HFCD Family: Homo-oligomeric flavin-containing Cys decarboxylases, HFCD Phyre2 PDB 2ejb chain A Region: 6 - 180 Aligned: 162 Modelled: 175 Confidence: 100.0% Identity: 13% PDB header:lyase Chain: A: PDB Molecule:probable aromatic acid decarboxylase; PDBTitle: crystal structure of phenylacrylic acid decarboxylase from2 aquifex aeolicus Phyre2 PDB 1qzu chain B Region: 4 - 151 Aligned: 146 Modelled: 148 Confidence: 100.0% Identity: 29% PDB header:lyase Chain: B: PDB Molecule:hypothetical protein mds018; PDBTitle: crystal structure of human phosphopantothenoylcysteine decarboxylase Phyre2 PDB 3zqu chain A Region: 3 - 189 Aligned: 181 Modelled: 187 Confidence: 100.0% Identity: 16% PDB header:lyase Chain: A: PDB Molecule:probable aromatic acid decarboxylase; PDBTitle: structure of a probable aromatic acid decarboxylase Phyre2 PDB 2et6 chain A Region: 1 - 282 Aligned: 273 Modelled: 281 Confidence: 98.2% Identity: 17% PDB header:oxidoreductase Chain: A: PDB Molecule:(3r)-hydroxyacyl-coa dehydrogenase; PDBTitle: (3r)-hydroxyacyl-coa dehydrogenase domain of candida tropicalis2 peroxisomal multifunctional enzyme type 2 Phyre2 PDB 1rkx chain A Region: 182 - 280 Aligned: 83 Modelled: 83 Confidence: 97.7% Identity: 16% Fold: NAD(P)-binding Rossmann-fold domains Superfamily: NAD(P)-binding Rossmann-fold domains Family: Tyrosine-dependent oxidoreductases Phyre2 PDB 2q1u chain A Region: 185 - 280 Aligned: 78 Modelled: 80 Confidence: 97.6% Identity: 19% PDB header:sugar binding protein Chain: A: PDB Molecule:putative nucleotide sugar epimerase/ dehydratase; PDBTitle: crystal structure of the bordetella bronchiseptica enzyme wbmf in2 complex with nad+ and udp Phyre2 PDB 1z7e chain C Region: 180 - 279 Aligned: 81 Modelled: 84 Confidence: 97.6% Identity: 17% PDB header:hydrolase Chain: C: PDB Molecule:protein arna; PDBTitle: crystal structure of full length arna Phyre2 PDB 1wvg chain A domain 1 Region: 182 - 280 Aligned: 83 Modelled: 83 Confidence: 97.6% Identity: 13% Fold: NAD(P)-binding Rossmann-fold domains Superfamily: NAD(P)-binding Rossmann-fold domains Family: Tyrosine-dependent oxidoreductases Phyre2 1 d1u7za_ 2 c2gk4A_ 3 d1p9oa_ 4 d1g5qa_ 5 d1p3y1_ 6 c3qjgD_ 7 c1mvlA_ 8 d1mvla_ 9 c3mcuF_ 10 c3lqkA_ 11 d1qzua_ 12 d1sbza_ 13 c2ejbA_ 14 c1qzuB_ 15 c3zquA_ 16 c2et6A_ 17 d1rkxa_ 18 c2q1uA_ 19 c1z7eC_ 20 d1wvga1 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 306 307 308 309 310 311 312 313 314 315 316 317 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 336 337 338 339 340 341 342 343 344 345 346 347 348 349 350 351 352 353 354 355 356 357 358 359 360 361 362 363 364 365 366 367 368 369 370 371 372 373 374 375 376 377 378 379 380 381 382 383 384 385 386 387 388 389 390 391 392 393 394 395 396 397 398 399 400 401 402 403 404 405 406 407 408 409 410 411 412 413 414 415 416 417 418 419 420 421 422 423 424 425 426 427 428 429 430 431 432 433 434 435 436 437 438 439 440 441 442 443 444 445 446 447 448 449 450 451 452 453 454 455 456 457 458 459 460 461 462 463 464 465 466 467 468 469 470 471 472 473 474 475 476 477 478 479 480 481 482 483 484 485 486 487 488 489 490 491 492 493 494 495 496 497 498 499