Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	A	F	A	S	L	I	E	R	Q	R	I	R	L	L	L	A	L	L	F	G	A	C	G	T	L	A	F	S	P	Y	D	V	W	P	A	A	I	I	S	L	M	G	L	Q	A	L	T	F	N	R	R	P	L	Q	S	A	A	I	G
Secondary structure
SS confidence
Disorder		?	?	?	?		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		F	C	W	G	F	G	L	F	G	S	G	I	N	W	V	Y	V	S	I	A	T	F	G	G	M	P	G	P	V	N	I	F	L	V	V	L	L	A	A	Y	L	S	L	Y	T	G	L	F	A	G	V	L	S	R	L	W	P	K	T	T
Secondary structure
SS confidence
Disorder																																																											?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		W	L	R	V	A	I	A	A	P	A	L	W	Q	V	T	E	F	L	R	G	W	V	L	T	G	F	P	W	L	Q	F	G	Y	S	Q	I	D	G	P	L	K	G	L	A	P	I	M	G	V	E	A	I	N	F	L	L	M	M	V	S
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		G	L	L	A	L	A	L	V	K	R	N	W	R	P	L	V	V	A	V	V	L	F	A	L	P	F	P	L	R	Y	I	Q	W	F	T	P	Q	P	E	K	T	I	Q	V	S	M	V	Q	G	D	I	P	Q	S	L	K	W	D	E	G
Secondary structure
SS confidence
Disorder											?																						?	?	?	?	?	?	?	?																		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		Q	L	L	N	T	L	K	I	Y	Y	N	A	T	A	P	L	M	G	K	S	S	L	I	I	W	P	E	S	A	I	T	D	L	E	I	N	Q	Q	P	F	L	K	A	L	D	G	E	L	R	D	K	G	S	S	L	V	T	G	I	V
Secondary structure
SS confidence
Disorder																?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		D	A	R	L	N	K	Q	N	R	Y	D	T	Y	N	T	I	I	T	L	G	K	G	A	P	Y	S	Y	E	S	A	D	R	Y	N	K	N	H	L	V	P	F	G	E	F	V	P	L	E	S	I	L	R	P	L	A	P	F	F	D	L
Secondary structure
SS confidence
Disorder			?		?	?	?	?																	?	?	?	?																																	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		P	M	S	S	F	S	R	G	P	Y	I	Q	P	P	L	S	A	N	G	I	E	L	T	A	A	I	C	Y	E	I	I	L	G	E	Q	V	R	D	N	F	R	P	D	T	D	Y	L	L	T	I	S	N	D	A	W	F	G	K	S	I
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		G	P	W	Q	H	F	Q	M	A	R	M	R	A	L	E	L	A	R	P	L	L	R	S	T	N	N	G	I	T	A	V	I	G	P	Q	G	E	I	Q	A	M	I	P	Q	F	T	R	E	V	L	T	T	N	V	T	P	T	T	G	L
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.
Sequence		T	P	Y	A	R	T	G	N	W	P	L	W	V	L	T	A	L	F	G	F	A	A	V	L	M	S	L	R	Q	R	R	K
Secondary structure
SS confidence
Disorder																													?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1uf5 chain A Region: 219 - 489 Aligned: 256 Modelled: 271 Confidence: 100.0% Identity: 18% Fold: Carbon-nitrogen hydrolase Superfamily: Carbon-nitrogen hydrolase Family: Carbamilase Phyre2 PDB 2plq chain A Region: 215 - 476 Aligned: 234 Modelled: 242 Confidence: 100.0% Identity: 15% PDB header:hydrolase Chain: A: PDB Molecule:aliphatic amidase; PDBTitle: crystal structure of the amidase from geobacillus pallidus rapc8 Phyre2 PDB 2vhi chain G Region: 218 - 477 Aligned: 236 Modelled: 245 Confidence: 100.0% Identity: 17% PDB header:hydrolase Chain: G: PDB Molecule:cg3027-pa; PDBTitle: crystal structure of a pyrimidine degrading enzyme from2 drosophila melanogaster Phyre2 PDB 1ems chain B Region: 218 - 476 Aligned: 233 Modelled: 259 Confidence: 100.0% Identity: 17% PDB header:antitumor protein Chain: B: PDB Molecule:nit-fragile histidine triad fusion protein; PDBTitle: crystal structure of the c. elegans nitfhit protein Phyre2 PDB 2e2k chain C Region: 221 - 476 Aligned: 227 Modelled: 237 Confidence: 100.0% Identity: 18% PDB header:hydrolase Chain: C: PDB Molecule:formamidase; PDBTitle: helicobacter pylori formamidase amif contains a fine-tuned cysteine-2 glutamate-lysine catalytic triad Phyre2 PDB 2w1v chain A Region: 220 - 476 Aligned: 227 Modelled: 257 Confidence: 100.0% Identity: 15% PDB header:hydrolase Chain: A: PDB Molecule:nitrilase homolog 2; PDBTitle: crystal structure of mouse nitrilase-2 at 1.4a resolution Phyre2 PDB 1ems chain A domain 2 Region: 218 - 476 Aligned: 234 Modelled: 259 Confidence: 100.0% Identity: 17% Fold: Carbon-nitrogen hydrolase Superfamily: Carbon-nitrogen hydrolase Family: Nitrilase Phyre2 PDB 3hkx chain A Region: 218 - 486 Aligned: 232 Modelled: 251 Confidence: 100.0% Identity: 22% PDB header:hydrolase Chain: A: PDB Molecule:amidase; PDBTitle: crystal structure analysis of an amidase from nesterenkonia sp. Phyre2 PDB 1f89 chain A Region: 219 - 476 Aligned: 224 Modelled: 238 Confidence: 100.0% Identity: 22% Fold: Carbon-nitrogen hydrolase Superfamily: Carbon-nitrogen hydrolase Family: Nitrilase Phyre2 PDB 2e11 chain B Region: 220 - 476 Aligned: 218 Modelled: 240 Confidence: 100.0% Identity: 22% PDB header:hydrolase Chain: B: PDB Molecule:hydrolase; PDBTitle: the crystal structure of xc1258 from xanthomonas campestris: a cn-2 hydrolase superfamily protein with an arsenic adduct in the active3 site Phyre2 PDB 1j31 chain A Region: 221 - 476 Aligned: 214 Modelled: 235 Confidence: 100.0% Identity: 17% Fold: Carbon-nitrogen hydrolase Superfamily: Carbon-nitrogen hydrolase Family: Carbamilase Phyre2 PDB 3n05 chain B Region: 219 - 480 Aligned: 233 Modelled: 246 Confidence: 100.0% Identity: 20% PDB header:ligase Chain: B: PDB Molecule:nh(3)-dependent nad(+) synthetase; PDBTitle: crystal structure of nh3-dependent nad+ synthetase from streptomyces2 avermitilis Phyre2 PDB 3dla chain D Region: 211 - 476 Aligned: 233 Modelled: 251 Confidence: 100.0% Identity: 17% PDB header:ligase Chain: D: PDB Molecule:glutamine-dependent nad(+) synthetase; PDBTitle: x-ray crystal structure of glutamine-dependent nad+ synthetase from2 mycobacterium tuberculosis bound to naad+ and don Phyre2 PDB 3ilv chain A Region: 220 - 478 Aligned: 217 Modelled: 243 Confidence: 100.0% Identity: 14% PDB header:ligase Chain: A: PDB Molecule:glutamine-dependent nad(+) synthetase; PDBTitle: crystal structure of a glutamine-dependent nad(+) synthetase2 from cytophaga hutchinsonii Phyre2 PDB 1sgv chain A domain 1 Region: 433 - 474 Aligned: 42 Modelled: 42 Confidence: 74.4% Identity: 19% Fold: PUA domain-like Superfamily: PUA domain-like Family: PUA domain Phyre2 PDB 4pga chain A Region: 381 - 447 Aligned: 62 Modelled: 67 Confidence: 58.7% Identity: 13% Fold: Glutaminase/Asparaginase Superfamily: Glutaminase/Asparaginase Family: Glutaminase/Asparaginase Phyre2 PDB 1zq1 chain A domain 2 Region: 367 - 447 Aligned: 76 Modelled: 81 Confidence: 47.0% Identity: 12% Fold: Glutaminase/Asparaginase Superfamily: Glutaminase/Asparaginase Family: Glutaminase/Asparaginase Phyre2 PDB 2wlt chain A Region: 381 - 447 Aligned: 62 Modelled: 67 Confidence: 45.4% Identity: 13% PDB header:hydrolase Chain: A: PDB Molecule:l-asparaginase; PDBTitle: the crystal structure of helicobacter pylori l-asparaginase2 at 1.4 a resolution Phyre2 PDB 2d6f chain A domain 2 Region: 366 - 447 Aligned: 77 Modelled: 82 Confidence: 43.1% Identity: 10% Fold: Glutaminase/Asparaginase Superfamily: Glutaminase/Asparaginase Family: Glutaminase/Asparaginase Phyre2 PDB 1xf1 chain A Region: 387 - 444 Aligned: 57 Modelled: 58 Confidence: 42.3% Identity: 12% PDB header:hydrolase Chain: A: PDB Molecule:c5a peptidase; PDBTitle: structure of c5a peptidase- a key virulence factor from2 streptococcus Phyre2 1 d1uf5a_ 2 c2plqA_ 3 c2vhiG_ 4 c1emsB_ 5 c2e2kC_ 6 c2w1vA_ 7 d1emsa2 8 c3hkxA_ 9 d1f89a_ 10 c2e11B_ 11 d1j31a_ 12 c3n05B_ 13 c3dlaD_ 14 c3ilvA_ 15 d1sgva1 16 d4pgaa_ 17 d1zq1a2 18 c2wltA_ 19 d2d6fa2 20 c1xf1A_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1uf5a_ 100.0 18 Fold:Carbon-nitrogen hydrolase Superfamily:Carbon-nitrogen hydrolase Family:Carbamilase 2 c2plqA_ 100.0 15 PDB header:hydrolase Chain: A: PDB Molecule:aliphatic amidase; PDBTitle: crystal structure of the amidase from geobacillus pallidus rapc8 3 c2vhiG_ 100.0 17 PDB header:hydrolase Chain: G: PDB Molecule:cg3027-pa; PDBTitle: crystal structure of a pyrimidine degrading enzyme from2 drosophila melanogaster 4 c1emsB_ 100.0 17 PDB header:antitumor protein Chain: B: PDB Molecule:nit-fragile histidine triad fusion protein; PDBTitle: crystal structure of the c. elegans nitfhit protein 5 c2e2kC_ 100.0 18 PDB header:hydrolase Chain: C: PDB Molecule:formamidase; PDBTitle: helicobacter pylori formamidase amif contains a fine-tuned cysteine-2 glutamate-lysine catalytic triad 6 c2w1vA_ 100.0 15 PDB header:hydrolase Chain: A: PDB Molecule:nitrilase homolog 2; PDBTitle: crystal structure of mouse nitrilase-2 at 1.4a resolution 7 d1emsa2 100.0 17 Fold:Carbon-nitrogen hydrolase Superfamily:Carbon-nitrogen hydrolase Family:Nitrilase 8 c3hkxA_ 100.0 22 PDB header:hydrolase Chain: A: PDB Molecule:amidase; PDBTitle: crystal structure analysis of an amidase from nesterenkonia sp. 9 d1f89a_ 100.0 22 Fold:Carbon-nitrogen hydrolase Superfamily:Carbon-nitrogen hydrolase Family:Nitrilase 10 c2e11B_ 100.0 22 PDB header:hydrolase Chain: B: PDB Molecule:hydrolase; PDBTitle: the crystal structure of xc1258 from xanthomonas campestris: a cn-2 hydrolase superfamily protein with an arsenic adduct in the active3 site 11 d1j31a_ 100.0 17 Fold:Carbon-nitrogen hydrolase Superfamily:Carbon-nitrogen hydrolase Family:Carbamilase 12 c3n05B_ 100.0 20 PDB header:ligase Chain: B: PDB Molecule:nh(3)-dependent nad(+) synthetase; PDBTitle: crystal structure of nh3-dependent nad+ synthetase from streptomyces2 avermitilis 13 c3dlaD_ 100.0 17 PDB header:ligase Chain: D: PDB Molecule:glutamine-dependent nad(+) synthetase; PDBTitle: x-ray crystal structure of glutamine-dependent nad+ synthetase from2 mycobacterium tuberculosis bound to naad+ and don 14 c3ilvA_ 100.0 14 PDB header:ligase Chain: A: PDB Molecule:glutamine-dependent nad(+) synthetase; PDBTitle: crystal structure of a glutamine-dependent nad(+) synthetase2 from cytophaga hutchinsonii 15 d1sgva1 74.4 19 Fold:PUA domain-like Superfamily:PUA domain-like Family:PUA domain 16 d4pgaa_ 58.7 13 Fold:Glutaminase/Asparaginase Superfamily:Glutaminase/Asparaginase Family:Glutaminase/Asparaginase 17 d1zq1a2 47.0 12 Fold:Glutaminase/Asparaginase Superfamily:Glutaminase/Asparaginase Family:Glutaminase/Asparaginase 18 c2wltA_ 45.4 13 PDB header:hydrolase Chain: A: PDB Molecule:l-asparaginase; PDBTitle: the crystal structure of helicobacter pylori l-asparaginase2 at 1.4 a resolution 19 d2d6fa2 43.1 10 Fold:Glutaminase/Asparaginase Superfamily:Glutaminase/Asparaginase Family:Glutaminase/Asparaginase 20 c1xf1A_ 42.3 12 PDB header:hydrolase Chain: A: PDB Molecule:c5a peptidase; PDBTitle: structure of c5a peptidase- a key virulence factor from2 streptococcus 21 d1o7ja_ not modelled 40.0 16 Fold:Glutaminase/Asparaginase Superfamily:Glutaminase/Asparaginase Family:Glutaminase/Asparaginase 22 c1zq1B_ not modelled 39.9 13 PDB header:lyase Chain: B: PDB Molecule:glutamyl-trna(gln) amidotransferase subunit d; PDBTitle: structure of gatde trna-dependent amidotransferase from2 pyrococcus abyssi 23 d3dhwc1 not modelled 38.7 12 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:ABC transporter ATPase domain-like 24 d1nnsa_ not modelled 36.4 11 Fold:Glutaminase/Asparaginase Superfamily:Glutaminase/Asparaginase Family:Glutaminase/Asparaginase 25 d2ocda1 not modelled 32.3 16 Fold:Glutaminase/Asparaginase Superfamily:Glutaminase/Asparaginase Family:Glutaminase/Asparaginase 26 c2d6fA_ not modelled 29.9 10 PDB header:ligase/rna Chain: A: PDB Molecule:glutamyl-trna(gln) amidotransferase subunit d; PDBTitle: crystal structure of glu-trna(gln) amidotransferase in the2 complex with trna(gln) 27 d1agxa_ not modelled 29.8 10 Fold:Glutaminase/Asparaginase Superfamily:Glutaminase/Asparaginase Family:Glutaminase/Asparaginase 28 c3qjaA_ not modelled 28.3 12 PDB header:lyase Chain: A: PDB Molecule:indole-3-glycerol phosphate synthase; PDBTitle: crystal structure of the mycobacterium tuberculosis indole-3-glycerol2 phosphate synthase (trpc) in apo form 29 c1wnfA_ not modelled 26.8 13 PDB header:hydrolase Chain: A: PDB Molecule:l-asparaginase; PDBTitle: crystal structure of ph0066 from pyrococcus horikoshii 30 c3cwcB_ not modelled 26.6 13 PDB header:transferase Chain: B: PDB Molecule:putative glycerate kinase 2; PDBTitle: crystal structure of putative glycerate kinase 2 from salmonella2 typhimurium lt2 31 d1vc4a_ not modelled 24.3 26 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 32 c3k2qA_ not modelled 22.7 34 PDB header:transferase Chain: A: PDB Molecule:pyrophosphate-dependent phosphofructokinase; PDBTitle: crystal structure of pyrophosphate-dependent2 phosphofructokinase from marinobacter aquaeolei, northeast3 structural genomics consortium target mqr88 33 c3gfoA_ not modelled 22.2 14 PDB header:atp binding protein Chain: A: PDB Molecule:cobalt import atp-binding protein cbio 1; PDBTitle: structure of cbio1 from clostridium perfringens: part of2 the abc transporter complex cbionq. 34 c2nydB_ not modelled 22.0 7 PDB header:unknown function Chain: B: PDB Molecule:upf0135 protein sa1388; PDBTitle: crystal structure of staphylococcus aureus hypothetical protein sa1388 35 d1wsaa_ not modelled 21.0 15 Fold:Glutaminase/Asparaginase Superfamily:Glutaminase/Asparaginase Family:Glutaminase/Asparaginase 36 c2higA_ not modelled 20.4 18 PDB header:transferase Chain: A: PDB Molecule:6-phospho-1-fructokinase; PDBTitle: crystal structure of phosphofructokinase apoenzyme from trypanosoma2 brucei. 37 d2axto1 not modelled 19.9 14 Fold:Transmembrane beta-barrels Superfamily:OMPA-like Family:PsbO-like 38 c2x24B_ not modelled 19.4 29 PDB header:ligase Chain: B: PDB Molecule:acetyl-coa carboxylase; PDBTitle: bovine acc2 ct domain in complex with inhibitor 39 c3o3cD_ not modelled 19.4 12 PDB header:transferase Chain: D: PDB Molecule:glycogen [starch] synthase isoform 2; PDBTitle: glycogen synthase basal state udp complex 40 d1g2912 not modelled 18.3 10 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:ABC transporter ATPase domain-like 41 d1js3a_ not modelled 18.2 9 Fold:PLP-dependent transferase-like Superfamily:PLP-dependent transferases Family:Pyridoxal-dependent decarboxylase 42 c1pixB_ not modelled 16.6 21 PDB header:lyase Chain: B: PDB Molecule:glutaconyl-coa decarboxylase a subunit; PDBTitle: crystal structure of the carboxyltransferase subunit of the2 bacterial ion pump glutaconyl-coenzyme a decarboxylase 43 d1jj7a_ not modelled 16.6 12 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:ABC transporter ATPase domain-like 44 d3d31a2 not modelled 15.4 10 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:ABC transporter ATPase domain-like 45 c3n6rF_ not modelled 15.2 20 PDB header:ligase Chain: F: PDB Molecule:propionyl-coa carboxylase, beta subunit; PDBTitle: crystal structure of the holoenzyme of propionyl-coa carboxylase (pcc) 46 c2yvaB_ not modelled 14.9 19 PDB header:dna binding protein Chain: B: PDB Molecule:dnaa initiator-associating protein diaa; PDBTitle: crystal structure of escherichia coli diaa 47 d1v43a3 not modelled 14.6 2 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:ABC transporter ATPase domain-like 48 c3o8oC_ not modelled 14.3 10 PDB header:transferase Chain: C: PDB Molecule:6-phosphofructokinase subunit alpha; PDBTitle: structure of phosphofructokinase from saccharomyces cerevisiae 49 d1oxxk2 not modelled 14.0 15 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:ABC transporter ATPase domain-like 50 c3glmD_ not modelled 14.0 19 PDB header:lyase Chain: D: PDB Molecule:glutaconyl-coa decarboxylase subunit a; PDBTitle: glutaconyl-coa decarboxylase a subunit from clostridium2 symbiosum co-crystallized with crotonyl-coa 51 c1f0xA_ not modelled 13.9 11 PDB header:oxidoreductase Chain: A: PDB Molecule:d-lactate dehydrogenase; PDBTitle: crystal structure of d-lactate dehydrogenase, a peripheral2 membrane respiratory enzyme. 52 d1pfka_ not modelled 13.9 9 Fold:Phosphofructokinase Superfamily:Phosphofructokinase Family:Phosphofructokinase 53 d1uyra1 not modelled 13.8 21 Fold:ClpP/crotonase Superfamily:ClpP/crotonase Family:Biotin dependent carboxylase carboxyltransferase domain 54 c1vrgE_ not modelled 13.4 22 PDB header:ligase Chain: E: PDB Molecule:propionyl-coa carboxylase, beta subunit; PDBTitle: crystal structure of propionyl-coa carboxylase, beta subunit (tm0716)2 from thermotoga maritima at 2.30 a resolution 55 d2zcta1 not modelled 13.1 14 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione peroxidase-like 56 d1i4na_ not modelled 13.0 18 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 57 c2f9yB_ not modelled 12.8 27 PDB header:ligase Chain: B: PDB Molecule:acetyl-coenzyme a carboxylase carboxyl transferase subunit PDBTitle: the crystal structure of the carboxyltransferase subunit of acc from2 escherichia coli 58 d2f9yb1 not modelled 12.8 27 Fold:ClpP/crotonase Superfamily:ClpP/crotonase Family:Biotin dependent carboxylase carboxyltransferase domain 59 d1sffa_ not modelled 12.5 12 Fold:PLP-dependent transferase-like Superfamily:PLP-dependent transferases Family:GABA-aminotransferase-like 60 c1x0uB_ not modelled 12.2 22 PDB header:lyase Chain: B: PDB Molecule:hypothetical methylmalonyl-coa decarboxylase alpha subunit; PDBTitle: crystal structure of the carboxyl transferase subunit of putative pcc2 of sulfolobus tokodaii 61 c3eurA_ not modelled 12.0 0 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of the c-terminal domain of uncharacterized protein2 from bacteroides fragilis nctc 9343 62 d2acfa1 not modelled 11.8 10 Fold:Macro domain-like Superfamily:Macro domain-like Family:Macro domain 63 c1drwA_ not modelled 11.8 12 PDB header:oxidoreductase Chain: A: PDB Molecule:dihydrodipicolinate reductase; PDBTitle: escherichia coli dhpr/nhdh complex 64 c3ogfA_ not modelled 11.6 22 PDB header:de novo protein Chain: A: PDB Molecule:de novo designed dimeric trefoil-fold sub-domain which PDBTitle: crystal structure of difoil-4p homo-trimer: de novo designed dimeric2 trefoil-fold sub-domain which forms homo-trimer assembly 65 c3u9rB_ not modelled 11.6 26 PDB header:ligase Chain: B: PDB Molecule:methylcrotonyl-coa carboxylase, beta-subunit; PDBTitle: crystal structure of p. aeruginosa 3-methylcrotonyl-coa carboxylase2 (mcc), beta subunit 66 d4pfka_ not modelled 11.5 20 Fold:Phosphofructokinase Superfamily:Phosphofructokinase Family:Phosphofructokinase 67 c1xnwD_ not modelled 11.5 24 PDB header:ligase Chain: D: PDB Molecule:propionyl-coa carboxylase complex b subunit; PDBTitle: acyl-coa carboxylase beta subunit from s. coelicolor (pccb),2 apo form #2, mutant d422i 68 c3trjC_ not modelled 11.4 20 PDB header:isomerase Chain: C: PDB Molecule:phosphoheptose isomerase; PDBTitle: structure of a phosphoheptose isomerase from francisella tularensis 69 d1l2ta_ not modelled 11.3 10 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:ABC transporter ATPase domain-like 70 d1vrga1 not modelled 11.1 22 Fold:ClpP/crotonase Superfamily:ClpP/crotonase Family:Biotin dependent carboxylase carboxyltransferase domain 71 c2a7sD_ not modelled 11.1 27 PDB header:ligase Chain: D: PDB Molecule:probable propionyl-coa carboxylase beta chain 5; PDBTitle: crystal structure of the acyl-coa carboxylase, accd5, from2 mycobacterium tuberculosis 72 c2yyzA_ not modelled 10.9 12 PDB header:transport protein Chain: A: PDB Molecule:sugar abc transporter, atp-binding protein; PDBTitle: crystal structure of sugar abc transporter, atp-binding protein 73 c1od4C_ not modelled 10.7 21 PDB header:ligase Chain: C: PDB Molecule:acetyl-coenzyme a carboxylase; PDBTitle: acetyl-coa carboxylase carboxyltransferase domain 74 c3fvqB_ not modelled 10.4 18 PDB header:hydrolase Chain: B: PDB Molecule:fe(3+) ions import atp-binding protein fbpc; PDBTitle: crystal structure of the nucleotide binding domain fbpc2 complexed with atp 75 d1xnya1 not modelled 10.3 24 Fold:ClpP/crotonase Superfamily:ClpP/crotonase Family:Biotin dependent carboxylase carboxyltransferase domain 76 c3ewlA_ not modelled 10.3 0 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized conserved protein bf1870; PDBTitle: crystal structure of conserved protein bf1870 of unknown function from2 bacteroides fragilis 77 c2nq2C_ not modelled 10.2 16 PDB header:metal transport Chain: C: PDB Molecule:hypothetical abc transporter atp-binding protein PDBTitle: an inward-facing conformation of a putative metal-chelate2 type abc transporter. 78 c1z47B_ not modelled 10.2 7 PDB header:ligand binding protein Chain: B: PDB Molecule:putative abc-transporter atp-binding protein; PDBTitle: structure of the atpase subunit cysa of the putative2 sulfate atp-binding cassette (abc) transporter from3 alicyclobacillus acidocaldarius 79 d1nmpa_ not modelled 10.0 12 Fold:NIF3 (NGG1p interacting factor 3)-like Superfamily:NIF3 (NGG1p interacting factor 3)-like Family:NIF3 (NGG1p interacting factor 3)-like 80 d1on3a1 not modelled 10.0 29 Fold:ClpP/crotonase Superfamily:ClpP/crotonase Family:Biotin dependent carboxylase carboxyltransferase domain 81 c2d62A_ not modelled 9.9 9 PDB header:sugar binding protein Chain: A: PDB Molecule:multiple sugar-binding transport atp-binding PDBTitle: crystal structure of multiple sugar binding transport atp-2 binding protein 82 c3d34A_ not modelled 9.8 44 PDB header:immune system Chain: A: PDB Molecule:spondin-2; PDBTitle: structure of the f-spondin domain of mindin 83 c3opyH_ not modelled 9.2 20 PDB header:transferase Chain: H: PDB Molecule:6-phosphofructo-1-kinase beta-subunit; PDBTitle: crystal structure of pichia pastoris phosphofructokinase in the t-2 state 84 c3opyB_ not modelled 9.2 20 PDB header:transferase Chain: B: PDB Molecule:6-phosphofructo-1-kinase beta-subunit; PDBTitle: crystal structure of pichia pastoris phosphofructokinase in the t-2 state 85 d1sgwa_ not modelled 9.0 14 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:ABC transporter ATPase domain-like 86 d2b7ka1 not modelled 9.0 9 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione peroxidase-like 87 c1m56G_ not modelled 8.8 7 PDB header:oxidoreductase Chain: G: PDB Molecule:cytochrome c oxidase; PDBTitle: structure of cytochrome c oxidase from rhodobactor2 sphaeroides (wild type) 88 c3dhwC_ not modelled 8.8 14 PDB header:membrane protein/hydrolase Chain: C: PDB Molecule:methionine import atp-binding protein metn; PDBTitle: crystal structure of methionine importer metni 89 c1uytC_ not modelled 8.7 21 PDB header:transferase Chain: C: PDB Molecule:acetyl-coa carboxylase; PDBTitle: acetyl-coa carboxylase carboxyltransferase domain 90 c1piiA_ not modelled 8.5 10 PDB header:bifunctional(isomerase and synthase) Chain: A: PDB Molecule:n-(5'phosphoribosyl)anthranilate isomerase; PDBTitle: three-dimensional structure of the bifunctional enzyme2 phosphoribosylanthranilate isomerase:3 indoleglycerolphosphate synthase from escherichia coli4 refined at 2.0 angstroms resolution 91 c3h0jA_ not modelled 8.5 21 PDB header:transferase Chain: A: PDB Molecule:acetyl-coa carboxylase; PDBTitle: crystal structure of the carboxyltransferase domain of2 acetyl-coenzyme a carboxylase in complex with compound 2 92 c3opyG_ not modelled 8.3 10 PDB header:transferase Chain: G: PDB Molecule:6-phosphofructo-1-kinase alpha-subunit; PDBTitle: crystal structure of pichia pastoris phosphofructokinase in the t-2 state 93 d1ohwa_ not modelled 8.3 14 Fold:PLP-dependent transferase-like Superfamily:PLP-dependent transferases Family:GABA-aminotransferase-like 94 c3ff6D_ not modelled 8.3 26 PDB header:ligase Chain: D: PDB Molecule:acetyl-coa carboxylase 2; PDBTitle: human acc2 ct domain with cp-640186 95 d1xrsa_ not modelled 8.1 20 Fold:TIM beta/alpha-barrel Superfamily:Cobalamin (vitamin B12)-dependent enzymes Family:D-lysine 5,6-aminomutase alpha subunit, KamD 96 d2awna2 not modelled 8.0 10 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:ABC transporter ATPase domain-like 97 c2p31B_ not modelled 8.0 11 PDB header:oxidoreductase Chain: B: PDB Molecule:glutathione peroxidase 7; PDBTitle: crystal structure of human glutathione peroxidase 7 98 c2it1B_ not modelled 8.0 10 PDB header:transport protein Chain: B: PDB Molecule:362aa long hypothetical maltose/maltodextrin PDBTitle: structure of ph0203 protein from pyrococcus horikoshii 99 d1prxa_ not modelled 7.8 23 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione peroxidase-like

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0