Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP31600
DateWed Jan 25 15:20:48 GMT 2012
Unique Job ID2b8055141b28ceca

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c2xpiA_
Top template information
PDB header:cell cycle
Chain: A: PDB Molecule:anaphase-promoting complex subunit cut9;
PDBTitle: crystal structure of apc/c hetero-tetramer cut9-hcn1
Confidence and coverage
Confidence:100.0% Coverage: 49%
485 residues ( 49% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
597 residues ( 60%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MKENNLNRVIGWSGLLLTSLLSTSALADNIGTSAEELGLSDYRHFVIYPRLDKALKAQKN
Secondary structure 
SS confidence 
Disorder  ??????
??????
??
??
?
Disorder confidence 
 
   .........70.........80.........90.........100.........110.........120
Sequence  NDEATAIREFEYIHQQVPDNIPLTLYLAEAYRHFGHDDRARLLLEDQLKRHPGDARLERS
Secondary structure 
SS confidence 
Disorder  ??
Disorder confidence 
 
   .........130.........140.........150.........160.........170.........180
Sequence  LAAIPVEVKSVTTVEELLAQQKACDAAPTLRCRSEVGQNALRLAQLPVARAQLNDATFAA
Secondary structure 
SS confidence 
Disorder 
?
???
?????
?
????
??
???
Disorder confidence 
 
   .........190.........200.........210.........220.........230.........240
Sequence  SPEGKTLRTDLLQRAIYLKQWSQADTLYNEARQQNTLSAAERRQWFDVLLAGQLDDRILA
Secondary structure 
SS confidence 
Disorder 
?
??
?
Disorder confidence 
 
   .........250.........260.........270.........280.........290.........300
Sequence  LQSQGIFTDPQSYITYATALAYRGEKARLQHYLIENKPLFTTDAQEKSWLYLLSKYSANP
Secondary structure 
SS confidence 
Disorder 
????
???
Disorder confidence 
 
   .........310.........320.........330.........340.........350.........360
Sequence  VQALANYTVQFADNRQYVVGATLPVLLKEGQYDAAQKLLATLPANEMLEERYAVSVATRN
Secondary structure 
SS confidence 
Disorder 
?
??
Disorder confidence 
 
   .........370.........380.........390.........400.........410.........420
Sequence  KAEALRLARLLYQQEPANLTRLDQLTWQLMQNEQSREAADLLLQRYPFQGDARVSQTLMA
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........430.........440.........450.........460.........470.........480
Sequence  RLASLLESHPYLATPAKVAILSKPLPLAEQRQWQSQLPGIADNCPAIVRLLGDMSPSYDA
Secondary structure 
SS confidence 
Disorder 
?
?????
??
?
??
?
Disorder confidence 
 
   .........490.........500.........510.........520.........530.........540
Sequence  AAWNRLAKCYRDTLPGVALYAWLQAEQRQPSAWQHRAVAYQAYQVEDYATALAAWQKISL
Secondary structure 
SS confidence 
Disorder 
????
?
Disorder confidence 
 
   .........550.........560.........570.........580.........590.........600
Sequence  HDMSNEDLLAAANTAQAAGNGAARDRWLQQAEKRGLGSNALYWWLHAQRYIPGQPELALN
Secondary structure 
SS confidence 
Disorder 
???
???
Disorder confidence 
 
   .........610.........620.........630.........640.........650.........660
Sequence  DLTRSINIAPSANAYVARATIYRQRHNVPAAVSDLRAALELEPNNSNTQAALGYALWDSG
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........670.........680.........690.........700.........710.........720
Sequence  DIAQSREMLEPAHKGLPDDPALIRQLAYVNQRLDDMPATQHYARLVIDDIDNQALITPLT
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........730.........740.........750.........760.........770.........780
Sequence  PEQNQQRFNFRRLHEEVGRRWTFSFDSSIGLRSGAMSTANNNVGGAAPGKSYRSYGQLEA
Secondary structure 
SS confidence 
Disorder 
?
??????????????
?
Disorder confidence 
 
   .........790.........800.........810.........820.........830.........840
Sequence  EYRIGRNMLLEGDLLSVYSRVFADTGENGVMMPVKNPMSGTGLRWKPLRDQIFFIAVEQQ
Secondary structure 
SS confidence 
Disorder 
?????
Disorder confidence 
 
   .........850.........860.........870.........880.........890.........900
Sequence  LPLNGQNGASDTMLRASASFFNGGKYSDEWHPNGSGWFAQNLYLDAAQYIRQDIQAWTAD
Secondary structure 
SS confidence 
Disorder 
????
??
?
?
Disorder confidence 
 
   .........910.........920.........930.........940.........950.........960
Sequence  YRVSWHQKVANGQTIEPYAHVQDNGYRDKGTQGAQLGGVGVRWNIWTGETHYDAWPHKVS
Secondary structure 
SS confidence 
Disorder 
???????????
????????????
Disorder confidence 
 
   .........970.........980.........990
Sequence  LGVEYQHTFKAINQRNGERNNAFLTIGVHW
Secondary structure 
SS confidence 
Disorder 
?
???
Disorder confidence 
 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 2xpi chain A

3D model

Region: 52 - 689
Aligned: 485
Modelled: 487
Confidence: 100.0%
Identity: 14%
PDB header:cell cycle
Chain: A: PDB Molecule:anaphase-promoting complex subunit cut9;
PDBTitle: crystal structure of apc/c hetero-tetramer cut9-hcn1

Phyre2

PDB 1w3b chain A

3D model

Region: 49 - 661
Aligned: 387
Modelled: 388
Confidence: 100.0%
Identity: 19%
Fold: alpha-alpha superhelix
Superfamily: TPR-like
Family: Tetratricopeptide repeat (TPR)

Phyre2

PDB 3fp4 chain A

3D model

Region: 34 - 690
Aligned: 454
Modelled: 456
Confidence: 100.0%
Identity: 12%
PDB header:transport protein
Chain: A: PDB Molecule:tpr repeat-containing protein yhr117w;
PDBTitle: crystal structure of tom71 complexed with ssa1 c-terminal2 fragment

Phyre2

PDB 2ooe chain A domain 1

3D model

Region: 71 - 691
Aligned: 494
Modelled: 495
Confidence: 100.0%
Identity: 11%
Fold: alpha-alpha superhelix
Superfamily: TPR-like
Family: HAT/Suf repeat

Phyre2

PDB 2gw1 chain A

3D model

Region: 150 - 706
Aligned: 465
Modelled: 468
Confidence: 100.0%
Identity: 12%
PDB header:protein transport
Chain: A: PDB Molecule:mitochondrial precursor proteins import receptor;
PDBTitle: crystal structure of the yeast tom70

Phyre2

PDB 2y4t chain A

3D model

Region: 184 - 703
Aligned: 377
Modelled: 377
Confidence: 100.0%
Identity: 15%
PDB header:chaperone
Chain: A: PDB Molecule:dnaj homolog subfamily c member 3;
PDBTitle: crystal structure of the human co-chaperone p58(ipk)

Phyre2

PDB 3ieg chain B

3D model

Region: 346 - 694
Aligned: 317
Modelled: 317
Confidence: 100.0%
Identity: 13%
PDB header:chaperone
Chain: B: PDB Molecule:dnaj homolog subfamily c member 3;
PDBTitle: crystal structure of p58(ipk) tpr domain at 2.5 a

Phyre2

PDB 1qsa chain A domain 1

3D model

Region: 50 - 610
Aligned: 432
Modelled: 447
Confidence: 99.9%
Identity: 15%
Fold: alpha-alpha superhelix
Superfamily: Bacterial muramidases
Family: Bacterial muramidases

Phyre2

PDB 3hym chain B

3D model

Region: 346 - 661
Aligned: 285
Modelled: 285
Confidence: 99.9%
Identity: 14%
PDB header:cell cycle, ligase
Chain: B: PDB Molecule:cell division cycle protein 16 homolog;
PDBTitle: insights into anaphase promoting complex tpr subdomain2 assembly from a cdc26-apc6 structure

Phyre2

PDB 2uy1 chain A

3D model

Region: 183 - 697
Aligned: 413
Modelled: 427
Confidence: 99.9%
Identity: 8%
PDB header:rna-binding protein
Chain: A: PDB Molecule:cleavage stimulation factor 77;
PDBTitle: crystal structure of cstf-77

Phyre2

PDB 1fch chain B

3D model

Region: 443 - 716
Aligned: 274
Modelled: 274
Confidence: 99.9%
Identity: 13%
PDB header:signaling protein
Chain: B: PDB Molecule:peroxisomal targeting signal 1 receptor;
PDBTitle: crystal structure of the pts1 complexed to the tpr region2 of human pex5

Phyre2

PDB 1fch chain A

3D model

Region: 446 - 716
Aligned: 271
Modelled: 271
Confidence: 99.9%
Identity: 13%
Fold: alpha-alpha superhelix
Superfamily: TPR-like
Family: Tetratricopeptide repeat (TPR)

Phyre2

PDB 1xi4 chain D

3D model

Region: 56 - 710
Aligned: 545
Modelled: 579
Confidence: 99.9%
Identity: 10%
PDB header:endocytosis/exocytosis
Chain: D: PDB Molecule:clathrin heavy chain;
PDBTitle: clathrin d6 coat

Phyre2

PDB 3pe3 chain D

3D model

Region: 541 - 708
Aligned: 168
Modelled: 168
Confidence: 99.9%
Identity: 21%
PDB header:transferase
Chain: D: PDB Molecule:udp-n-acetylglucosamine--peptide n-
PDBTitle: structure of human o-glcnac transferase and its complex with a peptide2 substrate

Phyre2

PDB 1dce chain A domain 1

3D model

Region: 346 - 666
Aligned: 288
Modelled: 291
Confidence: 99.9%
Identity: 8%
Fold: alpha-alpha superhelix
Superfamily: Protein prenylyltransferase
Family: Protein prenylyltransferase

Phyre2

PDB 3cvp chain A

3D model

Region: 446 - 708
Aligned: 257
Modelled: 258
Confidence: 99.9%
Identity: 12%
PDB header:transport protein
Chain: A: PDB Molecule:peroxisome targeting signal 1 receptor pex5;
PDBTitle: structure of peroxisomal targeting signal 1 (pts1) binding2 domain of trypanosoma brucei peroxin 5 (tbpex5)complexed3 to pts1 peptide (10-skl)

Phyre2

PDB 2ho1 chain B

3D model

Region: 479 - 688
Aligned: 210
Modelled: 210
Confidence: 99.9%
Identity: 11%
PDB header:protein binding
Chain: B: PDB Molecule:type 4 fimbrial biogenesis protein pilf;
PDBTitle: functional characterization of pseudomonas aeruginosa pilf

Phyre2

PDB 3mkr chain A

3D model

Region: 386 - 679
Aligned: 278
Modelled: 294
Confidence: 99.9%
Identity: 10%
PDB header:transport protein
Chain: A: PDB Molecule:coatomer subunit epsilon;
PDBTitle: crystal structure of yeast alpha/epsilon-cop subcomplex of the copi2 vesicular coat

Phyre2

PDB 1tno chain I

3D model

Region: 475 - 740
Aligned: 261
Modelled: 266
Confidence: 99.9%
Identity: 10%
PDB header:transferase
Chain: I: PDB Molecule:geranylgeranyltransferase type i alpha subunit;
PDBTitle: rat protein geranylgeranyltransferase type-i complexed with2 a ggpp analog and a kkksktkcvim peptide derived from k-3 ras4b

Phyre2

PDB 3mv3 chain B

3D model

Region: 387 - 691
Aligned: 258
Modelled: 260
Confidence: 99.9%
Identity: 9%
PDB header:protein transport
Chain: B: PDB Molecule:coatomer subunit epsilon;
PDBTitle: crystal structure of a-cop in complex with e-cop

Phyre2

PDB 3esl chain A

3D model

Region: 13 - 167
Aligned: 147
Modelled: 147
Confidence: 93.8%
Identity: 10%
PDB header:cell cycle
Chain: A: PDB Molecule:checkpoint serine/threonine-protein kinase bub1;
PDBTitle: crystal structure of the conserved n-terminal domain of the2 mitotic checkpoint component bub1

Phyre2

PDB 1p4t chain A

3D model

Region: 847 - 990
Aligned: 134
Modelled: 134
Confidence: 86.8%
Identity: 18%
Fold: Transmembrane beta-barrels
Superfamily: OMPA-like
Family: Outer membrane protein

Phyre2

PDB 3aeh chain B

3D model

Region: 893 - 988
Aligned: 89
Modelled: 89
Confidence: 84.7%
Identity: 15%
PDB header:hydrolase
Chain: B: PDB Molecule:hemoglobin-binding protease hbp autotransporter;
PDBTitle: integral membrane domain of autotransporter hbp

Phyre2

PDB 1qd6 chain C

3D model

Region: 826 - 947
Aligned: 122
Modelled: 122
Confidence: 78.3%
Identity: 13%
PDB header:membrane protein
Chain: C: PDB Molecule:protein (outer membrane phospholipase (ompla));
PDBTitle: outer membrane phospholipase a from escherichia coli

Phyre2
1
c2xpiA_
2
d1w3ba_
3
c3fp4A_
4
d2ooea1
5
c2gw1A_
6
c2y4tA_
7
c3iegB_
8
d1qsaa1
9
c3hymB_
10
c2uy1A_
11
c1fchB_
12
d1fcha_
13
c1xi4D_
14
c3pe3D_
15
d1dcea1
16
c3cvpA_
17
c2ho1B_
18
c3mkrA_
19
c1tnoI_
20
c3mv3B_
21
22
23
24
25
26
27
28
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31
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c3eslA_
119
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d1p4ta_
125
c3aehB_
126
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c1qd6C_
130
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c2xpiA_
100.0 14 PDB header:cell cycle
Chain: A: PDB Molecule:anaphase-promoting complex subunit cut9;
PDBTitle: crystal structure of apc/c hetero-tetramer cut9-hcn1
2d1w3ba_
100.0 19 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
3c3fp4A_
100.0 12 PDB header:transport protein
Chain: A: PDB Molecule:tpr repeat-containing protein yhr117w;
PDBTitle: crystal structure of tom71 complexed with ssa1 c-terminal2 fragment
4d2ooea1
100.0 11 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:HAT/Suf repeat
5c2gw1A_
100.0 12 PDB header:protein transport
Chain: A: PDB Molecule:mitochondrial precursor proteins import receptor;
PDBTitle: crystal structure of the yeast tom70
6c2y4tA_
100.0 15 PDB header:chaperone
Chain: A: PDB Molecule:dnaj homolog subfamily c member 3;
PDBTitle: crystal structure of the human co-chaperone p58(ipk)
7c3iegB_
100.0 13 PDB header:chaperone
Chain: B: PDB Molecule:dnaj homolog subfamily c member 3;
PDBTitle: crystal structure of p58(ipk) tpr domain at 2.5 a
8d1qsaa1
99.9 15 Fold:alpha-alpha superhelix
Superfamily:Bacterial muramidases
Family:Bacterial muramidases
9c3hymB_
99.9 14 PDB header:cell cycle, ligase
Chain: B: PDB Molecule:cell division cycle protein 16 homolog;
PDBTitle: insights into anaphase promoting complex tpr subdomain2 assembly from a cdc26-apc6 structure
10c2uy1A_
99.9 8 PDB header:rna-binding protein
Chain: A: PDB Molecule:cleavage stimulation factor 77;
PDBTitle: crystal structure of cstf-77
11c1fchB_
99.9 13 PDB header:signaling protein
Chain: B: PDB Molecule:peroxisomal targeting signal 1 receptor;
PDBTitle: crystal structure of the pts1 complexed to the tpr region2 of human pex5
12d1fcha_
99.9 13 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
13c1xi4D_
99.9 10 PDB header:endocytosis/exocytosis
Chain: D: PDB Molecule:clathrin heavy chain;
PDBTitle: clathrin d6 coat
14c3pe3D_
99.9 21 PDB header:transferase
Chain: D: PDB Molecule:udp-n-acetylglucosamine--peptide n-
PDBTitle: structure of human o-glcnac transferase and its complex with a peptide2 substrate
15d1dcea1
99.9 8 Fold:alpha-alpha superhelix
Superfamily:Protein prenylyltransferase
Family:Protein prenylyltransferase
16c3cvpA_
99.9 12 PDB header:transport protein
Chain: A: PDB Molecule:peroxisome targeting signal 1 receptor pex5;
PDBTitle: structure of peroxisomal targeting signal 1 (pts1) binding2 domain of trypanosoma brucei peroxin 5 (tbpex5)complexed3 to pts1 peptide (10-skl)
17c2ho1B_
99.9 11 PDB header:protein binding
Chain: B: PDB Molecule:type 4 fimbrial biogenesis protein pilf;
PDBTitle: functional characterization of pseudomonas aeruginosa pilf
18c3mkrA_
99.9 10 PDB header:transport protein
Chain: A: PDB Molecule:coatomer subunit epsilon;
PDBTitle: crystal structure of yeast alpha/epsilon-cop subcomplex of the copi2 vesicular coat
19c1tnoI_
99.9 10 PDB header:transferase
Chain: I: PDB Molecule:geranylgeranyltransferase type i alpha subunit;
PDBTitle: rat protein geranylgeranyltransferase type-i complexed with2 a ggpp analog and a kkksktkcvim peptide derived from k-3 ras4b
20c3mv3B_
99.9 9 PDB header:protein transport
Chain: B: PDB Molecule:coatomer subunit epsilon;
PDBTitle: crystal structure of a-cop in complex with e-cop
21c3draA_
not modelled 99.9 8 PDB header:transferase
Chain: A: PDB Molecule:protein
PDBTitle: candida albicans protein geranylgeranyltransferase-i2 complexed with ggpp
22d2h6fa1
not modelled 99.9 10 Fold:alpha-alpha superhelix
Superfamily:Protein prenylyltransferase
Family:Protein prenylyltransferase
23c3q75A_
not modelled 99.9 11 PDB header:transferase
Chain: A: PDB Molecule:farnesyltransferase alpha subunit;
PDBTitle: cryptococcus neoformans protein farnesyltransferase in complex with2 fpt-ii and tkcvvm peptide
24c2q7fA_
not modelled 99.9 14 PDB header:protein binding
Chain: A: PDB Molecule:yrrb protein;
PDBTitle: crystal structure of yrrb: a tpr protein with an unusual peptide-2 binding site
25d1d8da_
not modelled 99.9 9 Fold:alpha-alpha superhelix
Superfamily:Protein prenylyltransferase
Family:Protein prenylyltransferase
26c2vq2A_
not modelled 99.8 13 PDB header:structural protein
Chain: A: PDB Molecule:putative fimbrial biogenesis and twitching
PDBTitle: crystal structure of pilw, widely conserved type iv pilus2 biogenesis factor
27d1hz4a_
not modelled 99.8 15 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Transcription factor MalT domain III
28d1xnfa_
not modelled 99.8 13 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
29c3urzB_
not modelled 99.8 14 PDB header:protein binding
Chain: B: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of a hypothetical protein (bacova_03105) from2 bacteroides ovatus atcc 8483 at 2.19 a resolution
30c2r5sB_
not modelled 99.8 15 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:uncharacterized protein vp0806;
PDBTitle: the crystal structure of a domain of protein vp0806 (unknown function)2 from vibrio parahaemolyticus rimd 2210633
31c2pl2A_
not modelled 99.8 16 PDB header:protein binding
Chain: A: PDB Molecule:hypothetical conserved protein ttc0263;
PDBTitle: crystal structure of ttc0263: a thermophilic tpr protein in thermus2 thermophilus hb27
32c3as5A_
not modelled 99.7 13 PDB header:protein binding
Chain: A: PDB Molecule:mama;
PDBTitle: mama amb-1 p212121
33c3q15A_
not modelled 99.7 13 PDB header:hydrolase/kinase
Chain: A: PDB Molecule:response regulator aspartate phosphatase h;
PDBTitle: crystal structure of raph complexed with spo0f
34c1slyA_
not modelled 99.7 11 PDB header:glycosyltransferase
Chain: A: PDB Molecule:70-kda soluble lytic transglycosylase;
PDBTitle: complex of the 70-kda soluble lytic transglycosylase with2 bulgecin a
35d2onda1
not modelled 99.7 8 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:HAT/Suf repeat
36d1hh8a_
not modelled 99.7 16 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
37c3ulqA_
not modelled 99.7 8 PDB header:gene regulation/transcription activator
Chain: A: PDB Molecule:response regulator aspartate phosphatase f;
PDBTitle: crystal structure of the anti-activator rapf complexed with the2 response regulator coma dna binding domain
38c2hyzA_
not modelled 99.7 22 PDB header:de novo protein
Chain: A: PDB Molecule:synthetic consensus tpr protein;
PDBTitle: crystal structure of an 8 repeat consensus tpr superhelix2 (orthorombic crystal form)
39c1wao4_
not modelled 99.7 16 PDB header:hydrolase
Chain: 4: PDB Molecule:serine/threonine protein phosphatase 5;
PDBTitle: pp5 structure
40c3ly8A_
not modelled 99.7 11 PDB header:signaling protein
Chain: A: PDB Molecule:transcriptional activator cadc;
PDBTitle: crystal structure of mutant d471e of the periplasmic domain of cadc
41c2e2eA_
not modelled 99.7 17 PDB header:lyase
Chain: A: PDB Molecule:formate-dependent nitrite reductase complex nrfg subunit;
PDBTitle: tpr domain of nrfg mediates the complex formation between heme lyase2 and formate-dependent nitrite reductase in escherichia coli o157:h7
42d2c2la1
not modelled 99.6 15 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
43c3qdnA_
not modelled 99.6 12 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative thioredoxin protein;
PDBTitle: putative thioredoxin protein from salmonella typhimurium
44c3gyzB_
not modelled 99.6 15 PDB header:chaperone
Chain: B: PDB Molecule:chaperone protein ipgc;
PDBTitle: crystal structure of ipgc from shigella flexneri
45c3sf4B_
not modelled 99.6 13 PDB header:signaling protein/protein binding
Chain: B: PDB Molecule:g-protein-signaling modulator 2;
PDBTitle: crystal structure of the complex between the conserved cell polarity2 proteins inscuteable and lgn
46c2vsnB_
not modelled 99.6 14 PDB header:transferase
Chain: B: PDB Molecule:xcogt;
PDBTitle: structure and topological arrangement of an o-glcnac2 transferase homolog: insight into molecular control of3 intracellular glycosylation
47c2ifuA_
not modelled 99.6 12 PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:gamma-snap;
PDBTitle: crystal structure of a gamma-snap from danio rerio
48d1elwa_
not modelled 99.6 17 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
49c2xcbA_
not modelled 99.6 12 PDB header:protein binding
Chain: A: PDB Molecule:regulatory protein pcrh;
PDBTitle: crystal structure of pcrh in complex with the chaperone2 binding region of popd
50c2vyiA_
not modelled 99.6 20 PDB header:chaperone
Chain: A: PDB Molecule:sgta protein;
PDBTitle: crystal structure of the tpr domain of human sgt
51c2c2lD_
not modelled 99.6 15 PDB header:chaperone
Chain: D: PDB Molecule:carboxy terminus of hsp70-interacting protein;
PDBTitle: crystal structure of the chip u-box e3 ubiquitin ligase
52d1zu2a1
not modelled 99.6 13 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
53c3sz7A_
not modelled 99.5 16 PDB header:chaperone regulator
Chain: A: PDB Molecule:hsc70 cochaperone (sgt);
PDBTitle: crystal structure of the sgt2 tpr domain from aspergillus fumigatus
54d1a17a_
not modelled 99.5 17 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
55c3q49B_
not modelled 99.5 16 PDB header:ligase/chaperone
Chain: B: PDB Molecule:stip1 homology and u box-containing protein 1;
PDBTitle: crystal structure of the tpr domain of chip complexed with hsp70-c2 peptide
56c3gw4B_
not modelled 99.5 17 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of uncharacterized protein from deinococcus2 radiodurans. northeast structural genomics consortium target drr162b.
57c2dbaA_
not modelled 99.5 15 PDB header:structural protein
Chain: A: PDB Molecule:smooth muscle cell associated protein-1, isoform
PDBTitle: the solution structure of the tetratrico peptide repeat of2 human smooth muscle cell associated protein-1, isoform 2
58d1qqea_
not modelled 99.5 11 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
59d1hxia_
not modelled 99.5 13 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
60d2buga1
not modelled 99.5 17 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
61c2kckA_
not modelled 99.5 14 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:tpr repeat;
PDBTitle: nmr solution structure of the northeast structural genomics2 consortium (nesg) target mrr121a
62c1ihgA_
not modelled 99.4 16 PDB header:isomerase
Chain: A: PDB Molecule:cyclophilin 40;
PDBTitle: bovine cyclophilin 40, monoclinic form
63c2yhcA_
not modelled 99.4 17 PDB header:membrane protein
Chain: A: PDB Molecule:upf0169 lipoprotein yfio;
PDBTitle: structure of bamd from e. coli
64d1p5qa1
not modelled 99.4 20 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
65d1kt1a1
not modelled 99.4 10 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
66c3k9iA_
not modelled 99.4 17 PDB header:protein binding
Chain: A: PDB Molecule:bh0479 protein;
PDBTitle: crystal structure of putative protein binding protein (np_241345.1)2 from bacillus halodurans at 2.71 a resolution
67c2vgxA_
not modelled 99.4 7 PDB header:chaperone
Chain: A: PDB Molecule:chaperone sycd;
PDBTitle: structure of the yersinia enterocolitica type iii secretion2 translocator chaperone sycd
68c1ltxA_
not modelled 99.4 10 PDB header:transferase/protein binding
Chain: A: PDB Molecule:rab geranylgeranyltransferase alpha subunit;
PDBTitle: structure of rab escort protein-1 in complex with rab2 geranylgeranyl transferase and isoprenoid
69c3rkvA_
not modelled 99.4 11 PDB header:isomerase
Chain: A: PDB Molecule:putative peptidylprolyl isomerase;
PDBTitle: c-terminal domain of protein c56c10.10, a putative peptidylprolyl2 isomerase, from caenorhabditis elegans
70d1ihga1
not modelled 99.4 18 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
71d2fbna1
not modelled 99.4 16 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
72c2fbnA_
not modelled 99.4 16 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:70 kda peptidylprolyl isomerase, putative;
PDBTitle: plasmodium falciparum putative fk506-binding protein2 pfl2275c, c-terminal tpr-containing domain
73d1zbpa1
not modelled 99.3 17 Fold:ImpE-like
Superfamily:ImpE-like
Family:ImpE-like
74c2katA_
not modelled 99.3 14 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: solution structure of protein bpp2914 from bordetella2 parapertussis. northeast structural genomics consortium3 target bpr206
75c2xevB_
not modelled 99.3 16 PDB header:metal binding
Chain: B: PDB Molecule:ybgf;
PDBTitle: crystal structure of the tpr domain of xanthomonas2 campestris ybgf
76d1elra_
not modelled 99.3 12 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
77c3qkyA_
not modelled 99.3 15 PDB header:membrane protein
Chain: A: PDB Molecule:outer membrane assembly lipoprotein yfio;
PDBTitle: crystal structure of rhodothermus marinus bamd
78c1qz2B_
not modelled 99.3 23 PDB header:isomerase/chaperone
Chain: B: PDB Molecule:fk506-binding protein 4;
PDBTitle: crystal structure of fkbp52 c-terminal domain complex with2 the c-terminal peptide meevd of hsp90
79d1iyga_
not modelled 99.3 5 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
80c1na3A_
not modelled 99.3 25 PDB header:de novo protein
Chain: A: PDB Molecule:designed protein ctpr2;
PDBTitle: design of stable alpha-helical arrays from an idealized tpr2 motif
81d2hr2a1
not modelled 99.3 15 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:CT2138-like
82c1kt0A_
not modelled 99.2 17 PDB header:isomerase
Chain: A: PDB Molecule:51 kda fk506-binding protein;
PDBTitle: structure of the large fkbp-like protein, fkbp51, involved in steroid2 receptor complexes
83c3nf1A_
not modelled 99.2 13 PDB header:motor protein, transport protein
Chain: A: PDB Molecule:kinesin light chain 1;
PDBTitle: crystal structure of the tpr domain of kinesin light chain 1
84d1nzna_
not modelled 99.2 5 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
85c3ceqB_
not modelled 99.2 11 PDB header:motor protein, transport protein
Chain: B: PDB Molecule:kinesin light chain 2;
PDBTitle: the tpr domain of human kinesin light chain 2 (hklc2)
86c2l6jA_
not modelled 99.1 10 PDB header:protein binding
Chain: A: PDB Molecule:tpr repeat-containing protein associated with hsp90;
PDBTitle: tah1 complexed by meevd
87d1pc2a_
not modelled 99.1 11 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
88c2kcvA_
not modelled 99.1 12 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:tetratricopeptide repeat domain protein;
PDBTitle: solution nmr structure of tetratricopeptide repeat domain2 protein sru_0103 from salinibacter ruber, northeast3 structural genomics consortium (nesg) target srr115c
89c2if4A_
not modelled 99.1 15 PDB header:signaling protein
Chain: A: PDB Molecule:atfkbp42;
PDBTitle: crystal structure of a multi-domain immunophilin from2 arabidopsis thaliana
90c3e4bD_
not modelled 99.1 12 PDB header:protein binding
Chain: D: PDB Molecule:algk;
PDBTitle: crystal structure of algk from pseudomonas fluorescens wcs374r
91d1tjca_
not modelled 99.0 14 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
92d1y8ma1
not modelled 99.0 7 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
93c3q3hA_
not modelled 98.9 7 PDB header:transferase
Chain: A: PDB Molecule:hmw1c-like glycosyltransferase;
PDBTitle: crystal structure of the actinobacillus pleuropneumoniae hmw1c2 glycosyltransferase in complex with udp-glc
94c2avpA_
not modelled 98.9 23 PDB header:de novo protein
Chain: A: PDB Molecule:synthetic consensus tpr protein;
PDBTitle: crystal structure of an 8 repeat consensus tpr superhelix
95c3fflC_
not modelled 98.9 10 PDB header:cell cycle
Chain: C: PDB Molecule:anaphase-promoting complex subunit 7;
PDBTitle: crystal structure of the n-terminal domain of anaphase-2 promoting complex subunit 7
96c2kc7A_
not modelled 98.9 17 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:bfr218_protein;
PDBTitle: solution nmr structure of bacteroides fragilis protein2 bf1650. northeast structural genomics consortium target3 bfr218
97c3n71A_
not modelled 98.8 12 PDB header:transcription
Chain: A: PDB Molecule:histone lysine methyltransferase smyd1;
PDBTitle: crystal structure of cardiac specific histone methyltransferase smyd1
98d2ff4a2
not modelled 98.7 17 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:BTAD-like
99c3beeB_
not modelled 98.7 14 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:putative yfre protein;
PDBTitle: crystal structure of putative yfre protein from vibrio2 parahaemolyticus
100d2pqrb1
not modelled 98.6 8 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
101c2qfcB_
not modelled 98.3 8 PDB header:transcription regulation
Chain: B: PDB Molecule:plcr protein;
PDBTitle: crystal structure of bacillus thuringiensis plcr complexed with papr
102c2xm6A_
not modelled 98.2 9 PDB header:unknown function
Chain: A: PDB Molecule:protein corresponding to locus c5321 from cft073 e.coli
PDBTitle: crystal structure of the protein corresponding to locus c5321 from2 cft073 e.coli strain
103c3qwvA_
not modelled 98.0 13 PDB header:transferase
Chain: A: PDB Molecule:set and mynd domain-containing protein 2;
PDBTitle: crystal structure of histone lysine methyltransferase smyd2 in complex2 with the cofactor product adohcy
104c3oxgA_
not modelled 98.0 15 PDB header:transferase
Chain: A: PDB Molecule:set and mynd domain-containing protein 3;
PDBTitle: human lysine methyltransferase smyd3 in complex with adohcy (form iii)
105c3mekA_
not modelled 98.0 9 PDB header:transferase
Chain: A: PDB Molecule:set and mynd domain-containing protein 3;
PDBTitle: crystal structure of human histone-lysine n-2 methyltransferase smyd3 in complex with s-adenosyl-l-3 methionine
106c3mkqA_
not modelled 97.5 13 PDB header:transport protein
Chain: A: PDB Molecule:coatomer beta'-subunit;
PDBTitle: crystal structure of yeast alpha/betaprime-cop subcomplex of the copi2 vesicular coat
107c3lvhA_
not modelled 97.4 10 PDB header:structural protein
Chain: A: PDB Molecule:clathrin heavy chain 1;
PDBTitle: crystal structure of a clathrin heavy chain and clathrin light chain2 complex
108c2ff4B_
not modelled 97.3 19 PDB header:transcription
Chain: B: PDB Molecule:probable regulatory protein embr;
PDBTitle: mycobacterium tuberculosis embr in complex with low affinity2 phosphopeptide
109c2wviA_
not modelled 97.1 7 PDB header:transferase
Chain: A: PDB Molecule:mitotic checkpoint serine/threonine-protein
PDBTitle: crystal structure of the n-terminal domain of bubr1
110c2lahA_
not modelled 96.6 11 PDB header:cell cycle, apoptosis
Chain: A: PDB Molecule:mitotic checkpoint serine/threonine-protein kinase bub1;
PDBTitle: solution nmr structure of mitotic checkpoint serine/threonine-protein2 kinase bub1 n-terminal domain from homo sapiens, northeast structural3 genomics consortium target hr5460a (methods development)
111c3rjvA_
not modelled 96.4 12 PDB header:protein binding
Chain: A: PDB Molecule:putative sel1 repeat protein;
PDBTitle: crystal structure of a putative sel1 repeat protein (kpn_04481) from2 klebsiella pneumoniae subsp. pneumoniae at 1.65 a resolution
112d1iipa1
not modelled 96.4 12 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
113d1ouva_
not modelled 96.2 14 Fold:alpha-alpha superhelix
Superfamily:HCP-like
Family:HCP-like
114c2pziA_
not modelled 96.1 16 PDB header:transferase
Chain: A: PDB Molecule:probable serine/threonine-protein kinase pkng;
PDBTitle: crystal structure of protein kinase pkng from mycobacterium2 tuberculosis in complex with tetrahydrobenzothiophene ax20017
115c3txmA_
not modelled 95.8 13 PDB header:hydrolase, protein binding
Chain: A: PDB Molecule:26s proteasome regulatory complex subunit p42b;
PDBTitle: crystal structure of rpn6 from drosophila melanogaster, gd(3+) complex
116d2cfua2
not modelled 94.4 18 Fold:Metallo-hydrolase/oxidoreductase
Superfamily:Metallo-hydrolase/oxidoreductase
Family:Alkylsulfatase-like
117c3mkqB_
not modelled 94.2 15 PDB header:transport protein
Chain: B: PDB Molecule:coatomer subunit alpha;
PDBTitle: crystal structure of yeast alpha/betaprime-cop subcomplex of the copi2 vesicular coat
118c3eslA_
93.8 10 PDB header:cell cycle
Chain: A: PDB Molecule:checkpoint serine/threonine-protein kinase bub1;
PDBTitle: crystal structure of the conserved n-terminal domain of the2 mitotic checkpoint component bub1
119c2cfuA_
not modelled 93.7 18 PDB header:hydrolase
Chain: A: PDB Molecule:sdsa1;
PDBTitle: crystal structure of sdsa1, an alkylsulfatase from2 pseudomonas aeruginosa, in complex with 1-decane-sulfonic-3 acid.
120d1klxa_
not modelled 93.1 16 Fold:alpha-alpha superhelix
Superfamily:HCP-like
Family:HCP-like

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
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Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0