Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP32141
DateThu Jan 5 11:49:28 GMT 2012
Unique Job ID28e4d29287383b38

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template d1to3a_
Top template information
Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
Confidence and coverage
Confidence:100.0% Coverage:100%
291 residues (100% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MNKYTINDITRASGGFAMLAVDQREAMRMMFAAAGAPAPVADSVLTDFKVNAAKALSPYA
Secondary structure 
SS confidence 
Disorder  ?????
?
???????
Disorder confidence 
 
   .........70.........80.........90.........100.........110.........120
Sequence  SAILVDQQFCYRQVVEQNAIAKSCAMIVAADEFIPGNGIPVDSVVIDRKINPLQIKQDGG
Secondary structure 
SS confidence 
Disorder 
??
??
?
Disorder confidence 
 
   .........130.........140.........150.........160.........170.........180
Sequence  KALKLLVLWRSDEDAQQRLDMVKEFNELCHSHGLVSIIEPVVRPPRRGDKFDREQAIIDA
Secondary structure 
SS confidence 
Disorder 
?
?
????????
Disorder confidence 
 
   .........190.........200.........210.........220.........230.........240
Sequence  AKELGDSGADLYKVEMPLYGKGPQQELLCASQRLNDHINMPWVILSSGVDEKLFPRAVRV
Secondary structure 
SS confidence 
Disorder 
????
Disorder confidence 
 
   .........250.........260.........270.........280.........290..
Sequence  AMTAGASGFLAGRAVWASVVGLPDNELMLRDVCAPKLQQLGDIVDEMMAKRR
Secondary structure 
SS confidence 
Disorder 
????
Disorder confidence 
 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1to3 chain A

3D model

Region: 1 - 291
Aligned: 291
Modelled: 291
Confidence: 100.0%
Identity: 83%
Fold: TIM beta/alpha-barrel
Superfamily: Aldolase
Family: Class I aldolase

Phyre2

PDB 3jrk chain G

3D model

Region: 3 - 289
Aligned: 282
Modelled: 283
Confidence: 100.0%
Identity: 22%
PDB header:lyase
Chain: G: PDB Molecule:tagatose 1,6-diphosphate aldolase 2;
PDBTitle: a putative tagatose 1,6-diphosphate aldolase from streptococcus2 pyogenes

Phyre2

PDB 2qjh chain H

3D model

Region: 3 - 292
Aligned: 250
Modelled: 283
Confidence: 100.0%
Identity: 19%
PDB header:lyase
Chain: H: PDB Molecule:putative aldolase mj0400;
PDBTitle: m. jannaschii adh synthase covalently bound to2 dihydroxyacetone phosphate

Phyre2

PDB 3gnd chain C

3D model

Region: 3 - 289
Aligned: 242
Modelled: 270
Confidence: 100.0%
Identity: 17%
PDB header:lyase
Chain: C: PDB Molecule:aldolase lsrf;
PDBTitle: crystal structure of e. coli lsrf in complex with ribulose-5-phosphate

Phyre2

PDB 1ojx chain A

3D model

Region: 4 - 273
Aligned: 240
Modelled: 267
Confidence: 100.0%
Identity: 15%
Fold: TIM beta/alpha-barrel
Superfamily: Aldolase
Family: Class I aldolase

Phyre2

PDB 3fok chain H

3D model

Region: 3 - 281
Aligned: 259
Modelled: 279
Confidence: 100.0%
Identity: 14%
PDB header:structural genomics, unknown function
Chain: H: PDB Molecule:uncharacterized protein cgl0159;
PDBTitle: crystal structure of cgl0159 from corynebacterium2 glutamicum (brevibacterium flavum). northeast structural3 genomics target cgr115

Phyre2

PDB 1n7k chain A

3D model

Region: 41 - 258
Aligned: 197
Modelled: 211
Confidence: 99.2%
Identity: 13%
Fold: TIM beta/alpha-barrel
Superfamily: Aldolase
Family: Class I aldolase

Phyre2

PDB 1xi3 chain A

3D model

Region: 112 - 286
Aligned: 154
Modelled: 175
Confidence: 99.1%
Identity: 18%
Fold: TIM beta/alpha-barrel
Superfamily: Thiamin phosphate synthase
Family: Thiamin phosphate synthase

Phyre2

PDB 3qja chain A

3D model

Region: 47 - 271
Aligned: 179
Modelled: 201
Confidence: 98.8%
Identity: 16%
PDB header:lyase
Chain: A: PDB Molecule:indole-3-glycerol phosphate synthase;
PDBTitle: crystal structure of the mycobacterium tuberculosis indole-3-glycerol2 phosphate synthase (trpc) in apo form

Phyre2

PDB 1a53 chain A

3D model

Region: 52 - 259
Aligned: 166
Modelled: 179
Confidence: 98.8%
Identity: 20%
Fold: TIM beta/alpha-barrel
Superfamily: Ribulose-phoshate binding barrel
Family: Tryptophan biosynthesis enzymes

Phyre2

PDB 3f4w chain A

3D model

Region: 17 - 286
Aligned: 201
Modelled: 229
Confidence: 98.7%
Identity: 14%
PDB header:synthase, lyase
Chain: A: PDB Molecule:putative hexulose 6 phosphate synthase;
PDBTitle: the 1.65a crystal structure of 3-hexulose-6-phosphate2 synthase from salmonella typhimurium

Phyre2

PDB 1pii chain A domain 2

3D model

Region: 52 - 271
Aligned: 173
Modelled: 191
Confidence: 98.7%
Identity: 20%
Fold: TIM beta/alpha-barrel
Superfamily: Ribulose-phoshate binding barrel
Family: Tryptophan biosynthesis enzymes

Phyre2

PDB 3ajx chain A

3D model

Region: 17 - 271
Aligned: 195
Modelled: 213
Confidence: 98.7%
Identity: 14%
PDB header:lyase
Chain: A: PDB Molecule:3-hexulose-6-phosphate synthase;
PDBTitle: crystal structure of 3-hexulose-6-phosphate synthase

Phyre2

PDB 1j5t chain A

3D model

Region: 50 - 271
Aligned: 176
Modelled: 194
Confidence: 98.6%
Identity: 15%
Fold: TIM beta/alpha-barrel
Superfamily: Ribulose-phoshate binding barrel
Family: Tryptophan biosynthesis enzymes

Phyre2

PDB 2c3z chain A

3D model

Region: 50 - 259
Aligned: 168
Modelled: 192
Confidence: 98.6%
Identity: 17%
PDB header:lyase
Chain: A: PDB Molecule:indole-3-glycerol phosphate synthase;
PDBTitle: crystal structure of a truncated variant of indole-3-2 glycerol phosphate synthase from sulfolobus solfataricus

Phyre2

PDB 2tps chain A

3D model

Region: 112 - 287
Aligned: 160
Modelled: 176
Confidence: 98.6%
Identity: 13%
Fold: TIM beta/alpha-barrel
Superfamily: Thiamin phosphate synthase
Family: Thiamin phosphate synthase

Phyre2

PDB 3ru6 chain C

3D model

Region: 17 - 280
Aligned: 203
Modelled: 231
Confidence: 98.6%
Identity: 13%
PDB header:lyase
Chain: C: PDB Molecule:orotidine 5'-phosphate decarboxylase;
PDBTitle: 1.8 angstrom resolution crystal structure of orotidine 5'-phosphate2 decarboxylase (pyrf) from campylobacter jejuni subsp. jejuni nctc3 11168

Phyre2

PDB 3o63 chain B

3D model

Region: 112 - 287
Aligned: 151
Modelled: 176
Confidence: 98.6%
Identity: 19%
PDB header:transferase
Chain: B: PDB Molecule:probable thiamine-phosphate pyrophosphorylase;
PDBTitle: crystal structure of thiamin phosphate synthase from mycobacterium2 tuberculosis

Phyre2

PDB 1yxy chain A domain 1

3D model

Region: 48 - 255
Aligned: 178
Modelled: 191
Confidence: 98.5%
Identity: 12%
Fold: TIM beta/alpha-barrel
Superfamily: Ribulose-phoshate binding barrel
Family: NanE-like

Phyre2

PDB 1vc4 chain A

3D model

Region: 47 - 271
Aligned: 179
Modelled: 196
Confidence: 98.5%
Identity: 17%
Fold: TIM beta/alpha-barrel
Superfamily: Ribulose-phoshate binding barrel
Family: Tryptophan biosynthesis enzymes

Phyre2
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d1to3a_
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c3jrkG_
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c2qjhH_
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c3gndC_
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d1ojxa_
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c3fokH_
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d1n7ka_
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d1xi3a_
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c3qjaA_
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d1a53a_
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c3f4wA_
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d1piia2
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c3ajxA_
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d1j5ta_
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c2c3zA_
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d2tpsa_
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c3ru6C_
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c3o63B_
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d1yxya1
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1d1to3a_
100.0 83 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
2c3jrkG_
100.0 22 PDB header:lyase
Chain: G: PDB Molecule:tagatose 1,6-diphosphate aldolase 2;
PDBTitle: a putative tagatose 1,6-diphosphate aldolase from streptococcus2 pyogenes
3c2qjhH_
100.0 19 PDB header:lyase
Chain: H: PDB Molecule:putative aldolase mj0400;
PDBTitle: m. jannaschii adh synthase covalently bound to2 dihydroxyacetone phosphate
4c3gndC_
100.0 17 PDB header:lyase
Chain: C: PDB Molecule:aldolase lsrf;
PDBTitle: crystal structure of e. coli lsrf in complex with ribulose-5-phosphate
5d1ojxa_
100.0 15 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
6c3fokH_
100.0 14 PDB header:structural genomics, unknown function
Chain: H: PDB Molecule:uncharacterized protein cgl0159;
PDBTitle: crystal structure of cgl0159 from corynebacterium2 glutamicum (brevibacterium flavum). northeast structural3 genomics target cgr115
7d1n7ka_
99.2 13 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
8d1xi3a_
99.1 18 Fold:TIM beta/alpha-barrel
Superfamily:Thiamin phosphate synthase
Family:Thiamin phosphate synthase
9c3qjaA_
98.8 16 PDB header:lyase
Chain: A: PDB Molecule:indole-3-glycerol phosphate synthase;
PDBTitle: crystal structure of the mycobacterium tuberculosis indole-3-glycerol2 phosphate synthase (trpc) in apo form
10d1a53a_
98.8 20 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
11c3f4wA_
98.7 14 PDB header:synthase, lyase
Chain: A: PDB Molecule:putative hexulose 6 phosphate synthase;
PDBTitle: the 1.65a crystal structure of 3-hexulose-6-phosphate2 synthase from salmonella typhimurium
12d1piia2
98.7 20 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
13c3ajxA_
98.7 14 PDB header:lyase
Chain: A: PDB Molecule:3-hexulose-6-phosphate synthase;
PDBTitle: crystal structure of 3-hexulose-6-phosphate synthase
14d1j5ta_
98.6 15 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
15c2c3zA_
98.6 17 PDB header:lyase
Chain: A: PDB Molecule:indole-3-glycerol phosphate synthase;
PDBTitle: crystal structure of a truncated variant of indole-3-2 glycerol phosphate synthase from sulfolobus solfataricus
16d2tpsa_
98.6 13 Fold:TIM beta/alpha-barrel
Superfamily:Thiamin phosphate synthase
Family:Thiamin phosphate synthase
17c3ru6C_
98.6 13 PDB header:lyase
Chain: C: PDB Molecule:orotidine 5'-phosphate decarboxylase;
PDBTitle: 1.8 angstrom resolution crystal structure of orotidine 5'-phosphate2 decarboxylase (pyrf) from campylobacter jejuni subsp. jejuni nctc3 11168
18c3o63B_
98.6 19 PDB header:transferase
Chain: B: PDB Molecule:probable thiamine-phosphate pyrophosphorylase;
PDBTitle: crystal structure of thiamin phosphate synthase from mycobacterium2 tuberculosis
19d1yxya1
98.5 12 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:NanE-like
20d1vc4a_
98.5 17 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
21c3qc3B_
not modelled 98.4 16 PDB header:isomerase
Chain: B: PDB Molecule:d-ribulose-5-phosphate-3-epimerase;
PDBTitle: crystal structure of a d-ribulose-5-phosphate-3-epimerase (np_954699)2 from homo sapiens at 2.20 a resolution
22d1h1ya_
not modelled 98.4 14 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:D-ribulose-5-phosphate 3-epimerase
23c2v82A_
not modelled 98.4 15 PDB header:lyase
Chain: A: PDB Molecule:2-dehydro-3-deoxy-6-phosphogalactonate aldolase;
PDBTitle: kdpgal complexed to kdpgal
24d1i4na_
not modelled 98.4 14 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
25d1y0ea_
not modelled 98.3 10 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:NanE-like
26d1wbha1
not modelled 98.3 12 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
27c3q58A_
not modelled 98.3 15 PDB header:isomerase
Chain: A: PDB Molecule:n-acetylmannosamine-6-phosphate 2-epimerase;
PDBTitle: structure of n-acetylmannosamine-6-phosphate epimerase from salmonella2 enterica
28d1o0ya_
not modelled 98.2 12 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
29c3igsB_
not modelled 98.2 15 PDB header:isomerase
Chain: B: PDB Molecule:n-acetylmannosamine-6-phosphate 2-epimerase 2;
PDBTitle: structure of the salmonella enterica n-acetylmannosamine-6-phosphate2 2-epimerase
30c3ngjC_
not modelled 98.2 11 PDB header:lyase
Chain: C: PDB Molecule:deoxyribose-phosphate aldolase;
PDBTitle: crystal structure of a putative deoxyribose-phosphate aldolase from2 entamoeba histolytica
31d1xcfa_
not modelled 98.2 13 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
32c3exsB_
not modelled 98.2 13 PDB header:lyase
Chain: B: PDB Molecule:rmpd (hexulose-6-phosphate synthase);
PDBTitle: crystal structure of kgpdc from streptococcus mutans in2 complex with d-r5p
33d1q6oa_
not modelled 98.2 14 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Decarboxylase
34d2zdra2
not modelled 98.2 15 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:NeuB-like
35c3inpA_
not modelled 98.1 14 PDB header:isomerase
Chain: A: PDB Molecule:d-ribulose-phosphate 3-epimerase;
PDBTitle: 2.05 angstrom resolution crystal structure of d-ribulose-phosphate 3-2 epimerase from francisella tularensis.
36d1dosa_
not modelled 98.1 13 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class II FBP aldolase
37d1mxsa_
not modelled 98.1 10 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
38d1gvfa_
not modelled 98.1 14 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class II FBP aldolase
39d1rpxa_
not modelled 98.1 18 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:D-ribulose-5-phosphate 3-epimerase
40d1ub3a_
not modelled 98.1 14 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
41d1vlia2
not modelled 98.0 12 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:NeuB-like
42c1xuzA_
not modelled 98.0 14 PDB header:biosynthetic protein
Chain: A: PDB Molecule:polysialic acid capsule biosynthesis protein siac;
PDBTitle: crystal structure analysis of sialic acid synthase (neub)from2 neisseria meningitidis, bound to mn2+, phosphoenolpyruvate, and n-3 acetyl mannosaminitol
43d1rvga_
not modelled 98.0 16 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class II FBP aldolase
44d1mzha_
not modelled 98.0 14 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
45d1rd5a_
not modelled 98.0 13 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
46c3oa3A_
not modelled 98.0 18 PDB header:lyase
Chain: A: PDB Molecule:aldolase;
PDBTitle: crystal structure of a putative deoxyribose-phosphate aldolase from2 coccidioides immitis
47c1yadD_
not modelled 98.0 21 PDB header:transcription
Chain: D: PDB Molecule:regulatory protein teni;
PDBTitle: structure of teni from bacillus subtilis
48d1tqxa_
not modelled 98.0 14 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:D-ribulose-5-phosphate 3-epimerase
49c3ng3A_
not modelled 97.9 13 PDB header:lyase
Chain: A: PDB Molecule:deoxyribose-phosphate aldolase;
PDBTitle: crystal structure of deoxyribose phosphate aldolase from mycobacterium2 avium 104 in a schiff base with an unknown aldehyde
50c1vliA_
not modelled 97.9 10 PDB header:biosynthetic protein
Chain: A: PDB Molecule:spore coat polysaccharide biosynthesis protein spse;
PDBTitle: crystal structure of spore coat polysaccharide biosynthesis protein2 spse (bsu37870) from bacillus subtilis at 2.38 a resolution
51d1wv2a_
not modelled 97.9 17 Fold:TIM beta/alpha-barrel
Superfamily:ThiG-like
Family:ThiG-like
52d1vhca_
not modelled 97.9 12 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
53d1wa3a1
not modelled 97.8 13 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
54c2yw3E_
not modelled 97.8 15 PDB header:lyase
Chain: E: PDB Molecule:4-hydroxy-2-oxoglutarate aldolase/2-deydro-3-
PDBTitle: crystal structure analysis of the 4-hydroxy-2-oxoglutarate aldolase/2-2 deydro-3-deoxyphosphogluconate aldolase from tthb1
55d1o60a_
not modelled 97.8 14 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I DAHP synthetase
56c3gr7A_
not modelled 97.8 12 PDB header:oxidoreductase
Chain: A: PDB Molecule:nadph dehydrogenase;
PDBTitle: structure of oye from geobacillus kaustophilus, hexagonal2 crystal form
57c3c52B_
not modelled 97.8 12 PDB header:lyase
Chain: B: PDB Molecule:fructose-bisphosphate aldolase;
PDBTitle: class ii fructose-1,6-bisphosphate aldolase from2 helicobacter pylori in complex with3 phosphoglycolohydroxamic acid, a competitive inhibitor
58c3hf3A_
not modelled 97.7 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:chromate reductase;
PDBTitle: old yellow enzyme from thermus scotoductus sa-01
59d2flia1
not modelled 97.7 18 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:D-ribulose-5-phosphate 3-epimerase
60c3pg8B_
not modelled 97.7 15 PDB header:transferase
Chain: B: PDB Molecule:phospho-2-dehydro-3-deoxyheptonate aldolase;
PDBTitle: truncated form of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase2 from thermotoga maritima
61d1p1xa_
not modelled 97.7 16 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
62c2h90A_
not modelled 97.7 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:xenobiotic reductase a;
PDBTitle: xenobiotic reductase a in complex with coumarin
63c1piiA_
not modelled 97.7 20 PDB header:bifunctional(isomerase and synthase)
Chain: A: PDB Molecule:n-(5'phosphoribosyl)anthranilate isomerase;
PDBTitle: three-dimensional structure of the bifunctional enzyme2 phosphoribosylanthranilate isomerase:3 indoleglycerolphosphate synthase from escherichia coli4 refined at 2.0 angstroms resolution
64c3jr2D_
not modelled 97.6 15 PDB header:biosynthetic protein
Chain: D: PDB Molecule:hexulose-6-phosphate synthase sgbh;
PDBTitle: x-ray crystal structure of the mg-bound 3-keto-l-gulonate-6-phosphate2 decarboxylase from vibrio cholerae o1 biovar el tor str. n16961
65d1z41a1
not modelled 97.6 17 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
66d1vzwa1
not modelled 97.6 21 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Histidine biosynthesis enzymes
67d1d9ea_
not modelled 97.6 14 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I DAHP synthetase
68d1w0ma_
not modelled 97.6 20 Fold:TIM beta/alpha-barrel
Superfamily:Triosephosphate isomerase (TIM)
Family:Triosephosphate isomerase (TIM)
69c2y85D_
not modelled 97.5 17 PDB header:isomerase
Chain: D: PDB Molecule:phosphoribosyl isomerase a;
PDBTitle: crystal structure of mycobacterium tuberculosis phosphoribosyl2 isomerase with bound rcdrp
70d1dvja_
not modelled 97.5 16 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Decarboxylase
71d1h5ya_
not modelled 97.5 16 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Histidine biosynthesis enzymes
72c3sz8D_
not modelled 97.5 13 PDB header:transferase
Chain: D: PDB Molecule:2-dehydro-3-deoxyphosphooctonate aldolase 2;
PDBTitle: crystal structure of 2-dehydro-3-deoxyphosphooctonate aldolase from2 burkholderia pseudomallei
73c3stgA_
not modelled 97.5 12 PDB header:transferase
Chain: A: PDB Molecule:2-dehydro-3-deoxyphosphooctonate aldolase;
PDBTitle: crystal structure of a58p, del(n59), and loop 7 truncated mutant of 3-2 deoxy-d-manno-octulosonate 8-phosphate synthase (kdo8ps) from3 neisseria meningitidis
74d1km4a_
not modelled 97.5 16 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Decarboxylase
75d1dbta_
not modelled 97.5 11 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Decarboxylase
76d1xm3a_
not modelled 97.4 19 Fold:TIM beta/alpha-barrel
Superfamily:ThiG-like
Family:ThiG-like
77d1vcva1
not modelled 97.4 11 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
78d1vyra_
not modelled 97.4 13 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
79d1tqja_
not modelled 97.4 15 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:D-ribulose-5-phosphate 3-epimerase
80c3qyqC_
not modelled 97.4 17 PDB header:lyase
Chain: C: PDB Molecule:deoxyribose-phosphate aldolase, putative;
PDBTitle: 1.8 angstrom resolution crystal structure of a putative deoxyribose-2 phosphate aldolase from toxoplasma gondii me49
81d1ps9a1
not modelled 97.4 11 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
82c3tfxB_
not modelled 97.4 18 PDB header:lyase
Chain: B: PDB Molecule:orotidine 5'-phosphate decarboxylase;
PDBTitle: crystal structure of orotidine 5'-phosphate decarboxylase from2 lactobacillus acidophilus
83d1qopa_
not modelled 97.4 17 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
84c3q94B_
not modelled 97.3 13 PDB header:lyase
Chain: B: PDB Molecule:fructose-bisphosphate aldolase, class ii;
PDBTitle: the crystal structure of fructose 1,6-bisphosphate aldolase from2 bacillus anthracis str. 'ames ancestor'
85c3qm3C_
not modelled 97.3 16 PDB header:lyase
Chain: C: PDB Molecule:fructose-bisphosphate aldolase;
PDBTitle: 1.85 angstrom resolution crystal structure of fructose-bisphosphate2 aldolase (fba) from campylobacter jejuni
86c3s5oA_
not modelled 97.3 11 PDB header:lyase
Chain: A: PDB Molecule:4-hydroxy-2-oxoglutarate aldolase, mitochondrial;
PDBTitle: crystal structure of human 4-hydroxy-2-oxoglutarate aldolase bound to2 pyruvate
87d1hg3a_
not modelled 97.3 17 Fold:TIM beta/alpha-barrel
Superfamily:Triosephosphate isomerase (TIM)
Family:Triosephosphate isomerase (TIM)
88d1thfd_
not modelled 97.3 12 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Histidine biosynthesis enzymes
89d1fbaa_
not modelled 97.2 19 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
90c3tr2A_
not modelled 97.2 13 PDB header:lyase
Chain: A: PDB Molecule:orotidine 5'-phosphate decarboxylase;
PDBTitle: structure of a orotidine 5'-phosphate decarboxylase (pyrf) from2 coxiella burnetii
91c3g0sA_
not modelled 97.2 12 PDB header:lyase
Chain: A: PDB Molecule:dihydrodipicolinate synthase;
PDBTitle: dihydrodipicolinate synthase from salmonella typhimurium lt2
92c3ez4B_
not modelled 97.2 20 PDB header:transferase
Chain: B: PDB Molecule:3-methyl-2-oxobutanoate hydroxymethyltransferase;
PDBTitle: crystal structure of 3-methyl-2-oxobutanoate2 hydroxymethyltransferase from burkholderia pseudomallei
93c2h6rG_
not modelled 97.2 20 PDB header:isomerase
Chain: G: PDB Molecule:triosephosphate isomerase;
PDBTitle: crystal structure of triosephosphate isomerase (tim) from2 methanocaldococcus jannaschii
94c3labA_
not modelled 97.2 9 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:putative kdpg (2-keto-3-deoxy-6-phosphogluconate)
PDBTitle: crystal structure of a putative kdpg (2-keto-3-deoxy-6-2 phosphogluconate) aldolase from oleispira antarctica
95c2ze3A_
not modelled 97.2 17 PDB header:isomerase
Chain: A: PDB Molecule:dfa0005;
PDBTitle: crystal structure of dfa0005 complexed with alpha-ketoglutarate: a2 novel member of the icl/pepm superfamily from alkali-tolerant3 deinococcus ficus
96c2htmB_
not modelled 97.1 18 PDB header:biosynthetic protein
Chain: B: PDB Molecule:thiazole biosynthesis protein thig;
PDBTitle: crystal structure of ttha0676 from thermus thermophilus hb8
97d1ka9f_
not modelled 97.0 12 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Histidine biosynthesis enzymes
98d2a6na1
not modelled 97.0 13 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
99d1gwja_
not modelled 97.0 17 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
100d1eixa_
not modelled 97.0 13 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Decarboxylase
101c3mbfA_
not modelled 97.0 17 PDB header:lyase
Chain: A: PDB Molecule:fructose-bisphosphate aldolase;
PDBTitle: crystal structure of fructose bisphosphate aldolase from2 encephalitozoon cuniculi, bound to fructose 1,6-bisphosphate
102c2ehhE_
not modelled 97.0 13 PDB header:lyase
Chain: E: PDB Molecule:dihydrodipicolinate synthase;
PDBTitle: crystal structure of dihydrodipicolinate synthase from2 aquifex aeolicus
103c3b4uB_
not modelled 97.0 11 PDB header:lyase
Chain: B: PDB Molecule:dihydrodipicolinate synthase;
PDBTitle: crystal structure of dihydrodipicolinate synthase from agrobacterium2 tumefaciens str. c58
104d1vqta1
not modelled 97.0 15 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Decarboxylase
105c3elfA_
not modelled 97.0 13 PDB header:lyase
Chain: A: PDB Molecule:fructose-bisphosphate aldolase;
PDBTitle: structural characterization of tetrameric mycobacterium tuberculosis2 fructose 1,6-bisphosphate aldolase - substrate binding and catalysis3 mechanism of a class iia bacterial aldolase
106c3ldvB_
not modelled 97.0 13 PDB header:lyase
Chain: B: PDB Molecule:orotidine 5'-phosphate decarboxylase;
PDBTitle: 1.77 angstrom resolution crystal structure of orotidine 5'-2 phosphate decarboxylase from vibrio cholerae o1 biovar3 eltor str. n16961
107c1zcoA_
not modelled 96.9 15 PDB header:lyase
Chain: A: PDB Molecule:2-dehydro-3-deoxyphosphoheptonate aldolase;
PDBTitle: crystal structure of pyrococcus furiosus 3-deoxy-d-arabino-2 heptulosonate 7-phosphate synthase
108c2r8wB_
not modelled 96.8 14 PDB header:lyase
Chain: B: PDB Molecule:agr_c_1641p;
PDBTitle: the crystal structure of dihydrodipicolinate synthase (atu0899) from2 agrobacterium tumefaciens str. c58
109c3g8rA_
not modelled 96.8 16 PDB header:biosynthetic protein
Chain: A: PDB Molecule:probable spore coat polysaccharide biosynthesis protein e;
PDBTitle: crystal structure of putative spore coat polysaccharide biosynthesis2 protein e from chromobacterium violaceum atcc 12472
110c2iswB_
not modelled 96.8 16 PDB header:lyase
Chain: B: PDB Molecule:putative fructose-1,6-bisphosphate aldolase;
PDBTitle: structure of giardia fructose-1,6-biphosphate aldolase in2 complex with phosphoglycolohydroxamate
111c3bo9B_
not modelled 96.8 13 PDB header:oxidoreductase
Chain: B: PDB Molecule:putative nitroalkan dioxygenase;
PDBTitle: crystal structure of putative nitroalkan dioxygenase (tm0800) from2 thermotoga maritima at 2.71 a resolution
112c3kx6C_
not modelled 96.7 19 PDB header:lyase
Chain: C: PDB Molecule:fructose-bisphosphate aldolase;
PDBTitle: crystal structure of fructose-1,6-bisphosphate aldolase from babesia2 bovis at 2.1a resolution
113c3fs2A_
not modelled 96.7 15 PDB header:transferase
Chain: A: PDB Molecule:2-dehydro-3-deoxyphosphooctonate aldolase;
PDBTitle: crystal structure of 2-dehydro-3-deoxyphosphooctonate2 aldolase from bruciella melitensis at 1.85a resolution
114d2czda1
not modelled 96.7 15 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Decarboxylase
115c3kruC_
not modelled 96.7 13 PDB header:oxidoreductase
Chain: C: PDB Molecule:nadh:flavin oxidoreductase/nadh oxidase;
PDBTitle: crystal structure of the thermostable old yellow enzyme from2 thermoanaerobacter pseudethanolicus e39
116c2z6jB_
not modelled 96.7 20 PDB header:oxidoreductase
Chain: B: PDB Molecule:trans-2-enoyl-acp reductase ii;
PDBTitle: crystal structure of s. pneumoniae enoyl-acyl carrier2 protein reductase (fabk) in complex with an inhibitor
117c1zfjA_
not modelled 96.6 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:inosine monophosphate dehydrogenase;
PDBTitle: inosine monophosphate dehydrogenase (impdh; ec 1.1.1.205) from2 streptococcus pyogenes
118d1zfja1
not modelled 96.6 18 Fold:TIM beta/alpha-barrel
Superfamily:Inosine monophosphate dehydrogenase (IMPDH)
Family:Inosine monophosphate dehydrogenase (IMPDH)
119c3t4cD_
not modelled 96.6 17 PDB header:transferase
Chain: D: PDB Molecule:2-dehydro-3-deoxyphosphooctonate aldolase 1;
PDBTitle: crystal structure of 2-dehydro-3-deoxyphosphooctonate aldolase from2 burkholderia ambifaria
120d1oy0a_
not modelled 96.6 21 Fold:TIM beta/alpha-barrel
Superfamily:Phosphoenolpyruvate/pyruvate domain
Family:Ketopantoate hydroxymethyltransferase PanB

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
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Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0