Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	L	I	I	E	T	L	P	L	L	R	Q	Q	I	R	R	L	R	M	E	G	K	R	V	A	L	V	P	T	M	G	N	L	H	D	G	H	M	K	L	V	D	E	A	K	A	R	A	D	V	V	V	V	S	I	F	V	N	P	M
Secondary structure
SS confidence
Disorder		?				?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		Q	F	D	R	P	E	D	L	A	R	Y	P	R	T	L	Q	E	D	C	E	K	L	N	K	R	K	V	D	L	V	F	A	P	S	V	K	E	I	Y	P	N	G	T	E	T	H	T	Y	V	D	V	P	G	L	S	T	M	L	E	G
Secondary structure
SS confidence
Disorder					?	?																																																			?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		A	S	R	P	G	H	F	R	G	V	S	T	I	V	S	K	L	F	N	L	V	Q	P	D	I	A	C	F	G	E	K	D	F	Q	Q	L	A	L	I	R	K	M	V	A	D	M	G	F	D	I	E	I	V	G	V	P	I	M	R	A
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		K	D	G	L	A	L	S	S	R	N	G	Y	L	T	A	E	Q	R	K	I	A	P	G	L	Y	K	V	L	S	S	I	A	D	K	L	Q	A	G	E	R	D	L	D	E	I	I	T	I	A	G	Q	E	L	N	E	K	G	F	R	A
Secondary structure
SS confidence
Disorder														?	?																							?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.
Sequence		D	D	I	Q	I	R	D	A	D	T	L	L	E	V	S	E	T	S	K	R	A	V	I	L	V	A	A	W	L	G	D	A	R	L	I	D	N	K	M	V	E	L	A
Secondary structure
SS confidence
Disorder																																											?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1iho chain A Region: 1 - 282 Aligned: 282 Modelled: 282 Confidence: 100.0% Identity: 100% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Nucleotidylyl transferase Family: Pantothenate synthetase (Pantoate-beta-alanine ligase, PanC) Phyre2 PDB 2ejc chain A Region: 1 - 280 Aligned: 278 Modelled: 280 Confidence: 100.0% Identity: 47% PDB header:ligase Chain: A: PDB Molecule:pantoate--beta-alanine ligase; PDBTitle: crystal structure of pantoate--beta-alanine ligase (panc)2 from thermotoga maritima Phyre2 PDB 3mxt chain A Region: 2 - 282 Aligned: 278 Modelled: 281 Confidence: 100.0% Identity: 39% PDB header:ligase Chain: A: PDB Molecule:pantothenate synthetase; PDBTitle: crystal structure of pantoate-beta-alanine ligase from campylobacter2 jejuni Phyre2 PDB 3ag5 chain A Region: 1 - 282 Aligned: 275 Modelled: 282 Confidence: 100.0% Identity: 41% PDB header:ligase Chain: A: PDB Molecule:pantothenate synthetase; PDBTitle: crystal structure of pantothenate synthetase from staphylococcus2 aureus Phyre2 PDB 1v8f chain A Region: 1 - 281 Aligned: 275 Modelled: 281 Confidence: 100.0% Identity: 47% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Nucleotidylyl transferase Family: Pantothenate synthetase (Pantoate-beta-alanine ligase, PanC) Phyre2 PDB 3uk2 chain B Region: 1 - 280 Aligned: 275 Modelled: 280 Confidence: 100.0% Identity: 46% PDB header:ligase Chain: B: PDB Molecule:pantothenate synthetase; PDBTitle: the structure of pantothenate synthetase from burkholderia2 thailandensis Phyre2 PDB 3inn chain B Region: 1 - 280 Aligned: 269 Modelled: 280 Confidence: 100.0% Identity: 45% PDB header:ligase Chain: B: PDB Molecule:pantothenate synthetase; PDBTitle: crystal structure of pantoate-beta-alanine-ligase in complex2 with atp at low occupancy at 2.1 a resolution Phyre2 PDB 2a84 chain A domain 1 Region: 1 - 282 Aligned: 265 Modelled: 269 Confidence: 100.0% Identity: 44% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Nucleotidylyl transferase Family: Pantothenate synthetase (Pantoate-beta-alanine ligase, PanC) Phyre2 PDB 3n8h chain A Region: 1 - 282 Aligned: 256 Modelled: 268 Confidence: 100.0% Identity: 39% PDB header:ligase Chain: A: PDB Molecule:pantothenate synthetase; PDBTitle: crystal structure of pantoate-beta-alanine ligase from francisella2 tularensis Phyre2 PDB 3guz chain B Region: 1 - 176 Aligned: 167 Modelled: 176 Confidence: 100.0% Identity: 96% PDB header:ligase Chain: B: PDB Molecule:pantothenate synthetase; PDBTitle: structural and substrate-binding studies of pantothenate2 synthenate (ps)provide insights into homotropic inhibition3 by pantoate in ps's Phyre2 PDB 2x0k chain B Region: 1 - 192 Aligned: 159 Modelled: 169 Confidence: 98.2% Identity: 19% PDB header:transferase Chain: B: PDB Molecule:riboflavin biosynthesis protein ribf; PDBTitle: crystal structure of modular fad synthetase from2 corynebacterium ammoniagenes Phyre2 PDB 3glv chain B Region: 22 - 176 Aligned: 117 Modelled: 120 Confidence: 97.2% Identity: 21% PDB header:biosynthetic protein Chain: B: PDB Molecule:lipopolysaccharide core biosynthesis protein; PDBTitle: crystal structure of the lipopolysaccharide core biosynthesis protein2 from thermoplasma volcanium gss1 Phyre2 PDB 3gmi chain A Region: 4 - 164 Aligned: 130 Modelled: 138 Confidence: 97.0% Identity: 18% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:upf0348 protein mj0951; PDBTitle: crystal structure of a protein of unknown function from2 methanocaldococcus jannaschii Phyre2 PDB 3elb chain A Region: 19 - 98 Aligned: 73 Modelled: 67 Confidence: 97.0% Identity: 18% PDB header:transferase Chain: A: PDB Molecule:ethanolamine-phosphate cytidylyltransferase; PDBTitle: human ctp: phosphoethanolamine cytidylyltransferase in complex with2 cmp Phyre2 PDB 1coz chain A Region: 22 - 100 Aligned: 76 Modelled: 79 Confidence: 96.8% Identity: 24% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Nucleotidylyl transferase Family: Cytidylyltransferase Phyre2 PDB 2cyc chain B Region: 4 - 235 Aligned: 220 Modelled: 222 Confidence: 96.7% Identity: 15% PDB header:ligase Chain: B: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: crystal structure of tyrosyl-trna synthetase complexed with l-tyrosine2 from pyrococcus horikoshii Phyre2 PDB 1qjc chain A Region: 22 - 88 Aligned: 59 Modelled: 67 Confidence: 96.5% Identity: 24% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Nucleotidylyl transferase Family: Adenylyltransferase Phyre2 PDB 3op1 chain A Region: 21 - 92 Aligned: 72 Modelled: 72 Confidence: 96.5% Identity: 22% PDB header:transferase Chain: A: PDB Molecule:macrolide-efflux protein; PDBTitle: crystal structure of macrolide-efflux protein sp_1110 from2 streptococcus pneumoniae Phyre2 PDB 1mrz chain A domain 2 Region: 24 - 91 Aligned: 65 Modelled: 68 Confidence: 96.4% Identity: 22% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Nucleotidylyl transferase Family: Adenylyltransferase Phyre2 PDB 3ikz chain A Region: 23 - 192 Aligned: 127 Modelled: 137 Confidence: 96.4% Identity: 20% PDB header:transferase Chain: A: PDB Molecule:phosphopantetheine adenylyltransferase; PDBTitle: crystal structure of phosphopantetheine adenylyltransferase from2 burkholderia pseudomallei Phyre2 1 d1ihoa_ 2 c2ejcA_ 3 c3mxtA_ 4 c3ag5A_ 5 d1v8fa_ 6 c3uk2B_ 7 c3innB_ 8 d2a84a1 9 c3n8hA_ 10 c3guzB_ 11 c2x0kB_ 12 c3glvB_ 13 c3gmiA_ 14 c3elbA_ 15 d1coza_ 16 c2cycB_ 17 d1qjca_ 18 c3op1A_ 19 d1mrza2 20 c3ikzA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1ihoa_ 100.0 100 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Pantothenate synthetase (Pantoate-beta-alanine ligase, PanC) 2 c2ejcA_ 100.0 47 PDB header:ligase Chain: A: PDB Molecule:pantoate--beta-alanine ligase; PDBTitle: crystal structure of pantoate--beta-alanine ligase (panc)2 from thermotoga maritima 3 c3mxtA_ 100.0 39 PDB header:ligase Chain: A: PDB Molecule:pantothenate synthetase; PDBTitle: crystal structure of pantoate-beta-alanine ligase from campylobacter2 jejuni 4 c3ag5A_ 100.0 41 PDB header:ligase Chain: A: PDB Molecule:pantothenate synthetase; PDBTitle: crystal structure of pantothenate synthetase from staphylococcus2 aureus 5 d1v8fa_ 100.0 47 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Pantothenate synthetase (Pantoate-beta-alanine ligase, PanC) 6 c3uk2B_ 100.0 46 PDB header:ligase Chain: B: PDB Molecule:pantothenate synthetase; PDBTitle: the structure of pantothenate synthetase from burkholderia2 thailandensis 7 c3innB_ 100.0 45 PDB header:ligase Chain: B: PDB Molecule:pantothenate synthetase; PDBTitle: crystal structure of pantoate-beta-alanine-ligase in complex2 with atp at low occupancy at 2.1 a resolution 8 d2a84a1 100.0 44 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Pantothenate synthetase (Pantoate-beta-alanine ligase, PanC) 9 c3n8hA_ 100.0 39 PDB header:ligase Chain: A: PDB Molecule:pantothenate synthetase; PDBTitle: crystal structure of pantoate-beta-alanine ligase from francisella2 tularensis 10 c3guzB_ 100.0 96 PDB header:ligase Chain: B: PDB Molecule:pantothenate synthetase; PDBTitle: structural and substrate-binding studies of pantothenate2 synthenate (ps)provide insights into homotropic inhibition3 by pantoate in ps's 11 c2x0kB_ 98.2 19 PDB header:transferase Chain: B: PDB Molecule:riboflavin biosynthesis protein ribf; PDBTitle: crystal structure of modular fad synthetase from2 corynebacterium ammoniagenes 12 c3glvB_ 97.2 21 PDB header:biosynthetic protein Chain: B: PDB Molecule:lipopolysaccharide core biosynthesis protein; PDBTitle: crystal structure of the lipopolysaccharide core biosynthesis protein2 from thermoplasma volcanium gss1 13 c3gmiA_ 97.0 18 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:upf0348 protein mj0951; PDBTitle: crystal structure of a protein of unknown function from2 methanocaldococcus jannaschii 14 c3elbA_ 97.0 18 PDB header:transferase Chain: A: PDB Molecule:ethanolamine-phosphate cytidylyltransferase; PDBTitle: human ctp: phosphoethanolamine cytidylyltransferase in complex with2 cmp 15 d1coza_ 96.8 24 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Cytidylyltransferase 16 c2cycB_ 96.7 15 PDB header:ligase Chain: B: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: crystal structure of tyrosyl-trna synthetase complexed with l-tyrosine2 from pyrococcus horikoshii 17 d1qjca_ 96.5 24 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Adenylyltransferase 18 c3op1A_ 96.5 22 PDB header:transferase Chain: A: PDB Molecule:macrolide-efflux protein; PDBTitle: crystal structure of macrolide-efflux protein sp_1110 from2 streptococcus pneumoniae 19 d1mrza2 96.4 22 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Adenylyltransferase 20 c3ikzA_ 96.4 20 PDB header:transferase Chain: A: PDB Molecule:phosphopantetheine adenylyltransferase; PDBTitle: crystal structure of phosphopantetheine adenylyltransferase from2 burkholderia pseudomallei 21 c3e27B_ not modelled 96.3 14 PDB header:transferase Chain: B: PDB Molecule:nicotinate (nicotinamide) nucleotide PDBTitle: nicotinic acid mononucleotide (namn) adenylyltransferase2 from bacillus anthracis: product complex 22 d1o6ba_ not modelled 96.3 20 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Adenylyltransferase 23 c2b7lD_ not modelled 96.2 25 PDB header:transferase Chain: D: PDB Molecule:glycerol-3-phosphate cytidylyltransferase; PDBTitle: crystal structure of ctp:glycerol-3-phosphate2 cytidylyltransferase from staphylococcus aureus 24 c3nv7A_ not modelled 96.2 13 PDB header:transferase Chain: A: PDB Molecule:phosphopantetheine adenylyltransferase; PDBTitle: crystal structure of h.pylori phosphopantetheine adenylyltransferase2 mutant i4v/n76y 25 d1vlha_ not modelled 96.1 27 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Adenylyltransferase 26 c1t6zB_ not modelled 95.8 23 PDB header:transferase Chain: B: PDB Molecule:riboflavin kinase/fmn adenylyltransferase; PDBTitle: crystal structure of riboflavin bound tm379 27 d1tfua_ not modelled 95.6 25 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Adenylyltransferase 28 d1f9aa_ not modelled 95.4 13 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Adenylyltransferase 29 c1lw7A_ not modelled 95.2 14 PDB header:transferase Chain: A: PDB Molecule:transcriptional regulator nadr; PDBTitle: nadr protein from haemophilus influenzae 30 c3hl4B_ not modelled 95.2 19 PDB header:transferase Chain: B: PDB Molecule:choline-phosphate cytidylyltransferase a; PDBTitle: crystal structure of a mammalian ctp:phosphocholine2 cytidylyltransferase with cdp-choline 31 c3f3mA_ not modelled 94.9 17 PDB header:transferase Chain: A: PDB Molecule:phosphopantetheine adenylyltransferase; PDBTitle: six crystal structures of two phosphopantetheine2 adenylyltransferases reveal an alternative ligand binding3 mode and an associated structural change 32 c2cybA_ not modelled 94.8 18 PDB header:ligase Chain: A: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: crystal structure of tyrosyl-trna synthetase complexed with2 l-tyrosine from archaeoglobus fulgidus 33 c2r5wA_ not modelled 94.8 13 PDB header:hydrolase, transferase Chain: A: PDB Molecule:nicotinamide-nucleotide adenylyltransferase; PDBTitle: crystal structure of a bifunctional nmn2 adenylyltransferase/adp ribose pyrophosphatase from3 francisella tularensis 34 c2h29A_ not modelled 94.7 13 PDB header:transferase Chain: A: PDB Molecule:probable nicotinate-nucleotide PDBTitle: crystal structure of nicotinic acid mononucleotide2 adenylyltransferase from staphylococcus aureus: product3 bound form 1 35 c3nd5D_ not modelled 94.7 20 PDB header:transferase Chain: D: PDB Molecule:phosphopantetheine adenylyltransferase; PDBTitle: crystal structure of phosphopantetheine adenylyltransferase (ppat)2 from enterococcus faecalis 36 c1yunB_ not modelled 94.3 18 PDB header:transferase Chain: B: PDB Molecule:probable nicotinate-nucleotide PDBTitle: crystal structure of nicotinic acid mononucleotide2 adenylyltransferase from pseudomonas aeruginosa 37 d1m8pa2 not modelled 94.2 22 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:ATP sulfurylase catalytic domain 38 d1lw7a1 not modelled 93.9 24 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Adenylyltransferase 39 c1v47B_ not modelled 93.8 29 PDB header:transferase Chain: B: PDB Molecule:atp sulfurylase; PDBTitle: crystal structure of atp sulfurylase from thermus2 thermophillus hb8 in complex with aps 40 c2cyaA_ not modelled 93.6 17 PDB header:ligase Chain: A: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: crystal structure of tyrosyl-trna synthetase from aeropyrum pernix 41 d1jhda2 not modelled 93.5 28 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:ATP sulfurylase catalytic domain 42 d1ej2a_ not modelled 93.2 25 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Adenylyltransferase 43 d1od6a_ not modelled 93.1 20 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Adenylyltransferase 44 c2qjoB_ not modelled 92.9 17 PDB header:transferase, hydrolase Chain: B: PDB Molecule:bifunctional nmn adenylyltransferase/nudix hydrolase; PDBTitle: crystal structure of a bifunctional nmn adenylyltransferase/adp ribose2 pyrophosphatase (nadm) complexed with adprp and nad from3 synechocystis sp. 45 d1v47a2 not modelled 92.5 27 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:ATP sulfurylase catalytic domain 46 c3cr8C_ not modelled 92.5 12 PDB header:transferase Chain: C: PDB Molecule:sulfate adenylyltranferase, adenylylsulfate PDBTitle: hexameric aps kinase from thiobacillus denitrificans 47 d1kama_ not modelled 91.7 23 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Adenylyltransferase 48 c3h05A_ not modelled 91.4 10 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein vpa0413; PDBTitle: the crystal structure of a putative nicotinate-nucleotide2 adenylyltransferase from vibrio parahaemolyticus 49 d1g8fa2 not modelled 91.2 25 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:ATP sulfurylase catalytic domain 50 d1nuua_ not modelled 90.7 8 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Adenylyltransferase 51 c1jhdA_ not modelled 89.6 29 PDB header:transferase Chain: A: PDB Molecule:sulfate adenylyltransferase; PDBTitle: crystal structure of bacterial atp sulfurylase from the2 riftia pachyptila symbiont 52 c3focB_ not modelled 89.5 21 PDB header:ligase Chain: B: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: tryptophanyl-trna synthetase from giardia lamblia 53 d1kr2a_ not modelled 88.1 13 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Adenylyltransferase 54 c3do8B_ not modelled 88.1 36 PDB header:transferase Chain: B: PDB Molecule:phosphopantetheine adenylyltransferase; PDBTitle: the crystal structure of the protein with unknown function2 from archaeoglobus fulgidus 55 c2j5bA_ not modelled 88.0 14 PDB header:ligase Chain: A: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: structure of the tyrosyl trna synthetase from acanthamoeba2 polyphaga mimivirus complexed with tyrosynol 56 c1r6xA_ not modelled 87.2 26 PDB header:transferase Chain: A: PDB Molecule:atp:sulfate adenylyltransferase; PDBTitle: the crystal structure of a truncated form of yeast atp2 sulfurylase, lacking the c-terminal aps kinase-like domain,3 in complex with sulfate 57 c3jxeB_ not modelled 86.2 16 PDB header:ligase Chain: B: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: crystal structure of pyrococcus horikoshii tryptophanyl-trna2 synthetase in complex with trpamp 58 c2ip1A_ not modelled 85.6 16 PDB header:ligase Chain: A: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: crystal structure analysis of s. cerevisiae tryptophanyl trna2 synthetase 59 c2gksB_ not modelled 85.2 22 PDB header:transferase Chain: B: PDB Molecule:bifunctional sat/aps kinase; PDBTitle: crystal structure of the bi-functional atp sulfurylase-aps kinase from2 aquifex aeolicus, a chemolithotrophic thermophile 60 c1xnjB_ not modelled 85.2 18 PDB header:transferase Chain: B: PDB Molecule:bifunctional 3'-phosphoadenosine 5'-phosphosulfate PDBTitle: aps complex of human paps synthetase 1 61 c1q11A_ not modelled 85.1 14 PDB header:ligase Chain: A: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: crystal structure of an active fragment of human tyrosyl-trna2 synthetase with tyrosinol 62 d1x6va2 not modelled 84.5 20 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:ATP sulfurylase catalytic domain 63 c1m8pB_ not modelled 83.3 24 PDB header:transferase Chain: B: PDB Molecule:sulfate adenylyltransferase; PDBTitle: crystal structure of p. chrysogenum atp sulfurylase in the t-state 64 d1k4ma_ not modelled 82.5 26 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Adenylyltransferase 65 c1g8gB_ not modelled 79.8 24 PDB header:transferase Chain: B: PDB Molecule:sulfate adenylyltransferase; PDBTitle: atp sulfurylase from s. cerevisiae: the binary product complex with2 aps 66 c2yy5C_ not modelled 76.8 16 PDB header:ligase Chain: C: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: crystal structure of tryptophanyl-trna synthetase from mycoplasma2 pneumoniae 67 d1i6la_ not modelled 69.3 13 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 68 c3nvaB_ not modelled 69.1 17 PDB header:ligase Chain: B: PDB Molecule:ctp synthase; PDBTitle: dimeric form of ctp synthase from sulfolobus solfataricus 69 d1j1ua_ not modelled 66.4 14 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 70 d2f48a1 not modelled 66.3 23 Fold:Phosphofructokinase Superfamily:Phosphofructokinase Family:Phosphofructokinase 71 c2el7A_ not modelled 65.4 16 PDB header:ligase Chain: A: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: crystal structure of tryptophanyl-trna synthetase from thermus2 thermophilus 72 c3ctzA_ not modelled 64.5 14 PDB header:hydrolase Chain: A: PDB Molecule:xaa-pro aminopeptidase 1; PDBTitle: structure of human cytosolic x-prolyl aminopeptidase 73 c3igsB_ not modelled 63.1 12 PDB header:isomerase Chain: B: PDB Molecule:n-acetylmannosamine-6-phosphate 2-epimerase 2; PDBTitle: structure of the salmonella enterica n-acetylmannosamine-6-phosphate2 2-epimerase 74 c2g36A_ not modelled 61.0 20 PDB header:ligase Chain: A: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: crystal structure of tryptophanyl-trna synthetase (ec 6.1.1.2)2 (tryptophan-trna ligase)(trprs) (tm0492) from thermotoga maritima at3 2.50 a resolution 75 c2yv4A_ not modelled 61.0 21 PDB header:rna binding protein Chain: A: PDB Molecule:hypothetical protein ph0435; PDBTitle: crystal structure of c-terminal sua5 domain from pyrococcus horikoshii2 hypothetical sua5 protein ph0435 76 d1xjca_ not modelled 60.1 26 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Nitrogenase iron protein-like 77 c2higA_ not modelled 55.6 17 PDB header:transferase Chain: A: PDB Molecule:6-phospho-1-fructokinase; PDBTitle: crystal structure of phosphofructokinase apoenzyme from trypanosoma2 brucei. 78 d1n3la_ not modelled 54.8 17 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 79 c3m5wB_ not modelled 54.4 15 PDB header:ligase Chain: B: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: crystal structure of tryptophanyl-trna synthetase from2 campylobacter jejuni 80 c3p0jD_ not modelled 53.4 18 PDB header:ligase Chain: D: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: leishmania major tyrosyl-trna synthetase in complex with tyrosinol,2 triclinic crystal form 1 81 c3o8oC_ not modelled 52.6 15 PDB header:transferase Chain: C: PDB Molecule:6-phosphofructokinase subunit alpha; PDBTitle: structure of phosphofructokinase from saccharomyces cerevisiae 82 c1yi8C_ not modelled 52.0 21 PDB header:ligase Chain: C: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: crystal structure of tryptophanyl trrna synthetase ii from deinococcus2 radiodurans in complex with l-trp 83 c2ad5B_ not modelled 51.8 19 PDB header:ligase Chain: B: PDB Molecule:ctp synthase; PDBTitle: mechanisms of feedback regulation and drug resistance of ctp2 synthetases: structure of the e. coli ctps/ctp complex at 2.8-3 angstrom resolution. 84 c2qjfB_ not modelled 50.8 18 PDB header:transferase Chain: B: PDB Molecule:bifunctional 3'-phosphoadenosine 5'- PDBTitle: crystal structure of atp-sulfurylase domain of human paps2 synthetase 1 85 c1h3eA_ not modelled 50.7 17 PDB header:ligase Chain: A: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: tyrosyl-trna synthetase from thermus thermophilus complexed2 with wild-type trnatyr(gua) and with atp and tyrosinol 86 d1pfka_ not modelled 50.3 22 Fold:Phosphofructokinase Superfamily:Phosphofructokinase Family:Phosphofructokinase 87 d2a5la1 not modelled 48.4 11 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:WrbA-like 88 c3o8oB_ not modelled 47.7 15 PDB header:transferase Chain: B: PDB Molecule:6-phosphofructokinase subunit beta; PDBTitle: structure of phosphofructokinase from saccharomyces cerevisiae 89 c3opyB_ not modelled 47.3 16 PDB header:transferase Chain: B: PDB Molecule:6-phosphofructo-1-kinase beta-subunit; PDBTitle: crystal structure of pichia pastoris phosphofructokinase in the t-2 state 90 c3opyH_ not modelled 47.3 16 PDB header:transferase Chain: H: PDB Molecule:6-phosphofructo-1-kinase beta-subunit; PDBTitle: crystal structure of pichia pastoris phosphofructokinase in the t-2 state 91 d1sbza_ not modelled 45.5 24 Fold:Homo-oligomeric flavin-containing Cys decarboxylases, HFCD Superfamily:Homo-oligomeric flavin-containing Cys decarboxylases, HFCD Family:Homo-oligomeric flavin-containing Cys decarboxylases, HFCD 92 c3o6cA_ not modelled 45.4 52 PDB header:transferase Chain: A: PDB Molecule:pyridoxine 5'-phosphate synthase; PDBTitle: pyridoxal phosphate biosynthetic protein pdxj from campylobacter2 jejuni 93 d1fpza_ not modelled 45.2 21 Fold:(Phosphotyrosine protein) phosphatases II Superfamily:(Phosphotyrosine protein) phosphatases II Family:Dual specificity phosphatase-like 94 d1tzpa_ not modelled 44.8 43 Fold:Hedgehog/DD-peptidase Superfamily:Hedgehog/DD-peptidase Family:MepA-like 95 d4pfka_ not modelled 42.2 24 Fold:Phosphofructokinase Superfamily:Phosphofructokinase Family:Phosphofructokinase 96 c3opyE_ not modelled 40.9 16 PDB header:transferase Chain: E: PDB Molecule:6-phosphofructo-1-kinase alpha-subunit; PDBTitle: crystal structure of pichia pastoris phosphofructokinase in the t-2 state 97 c3opyG_ not modelled 40.2 16 PDB header:transferase Chain: G: PDB Molecule:6-phosphofructo-1-kinase alpha-subunit; PDBTitle: crystal structure of pichia pastoris phosphofructokinase in the t-2 state 98 c2gsjA_ not modelled 38.1 20 PDB header:hydrolase Chain: A: PDB Molecule:protein ppl-2; PDBTitle: cdna cloning and 1.75a crystal structure determination of2 ppl2, a novel chimerolectin from parkia platycephala seeds3 exhibiting endochitinolytic activity 99 c2jmlA_ not modelled 37.4 4 PDB header:transcription Chain: A: PDB Molecule:dna binding domain/transcriptional regulator; PDBTitle: solution structure of the n-terminal domain of cara repressor 100 c2p10D_ not modelled 37.0 23 PDB header:hydrolase Chain: D: PDB Molecule:mll9387 protein; PDBTitle: crystal structure of a putative phosphonopyruvate hydrolase (mll9387)2 from mesorhizobium loti maff303099 at 2.15 a resolution 101 c2ftpA_ not modelled 36.3 15 PDB header:lyase Chain: A: PDB Molecule:hydroxymethylglutaryl-coa lyase; PDBTitle: crystal structure of hydroxymethylglutaryl-coa lyase from pseudomonas2 aeruginosa 102 c3kuxA_ not modelled 36.3 16 PDB header:oxidoreductase Chain: A: PDB Molecule:putative oxidoreductase; PDBTitle: structure of the ypo2259 putative oxidoreductase from yersinia pestis 103 c2dx7B_ not modelled 35.8 23 PDB header:isomerase Chain: B: PDB Molecule:aspartate racemase; PDBTitle: crystal structure of pyrococcus horikoshii ot3 aspartate racemase2 complex with citric acid 104 d1pg5a2 not modelled 35.0 17 Fold:ATC-like Superfamily:Aspartate/ornithine carbamoyltransferase Family:Aspartate/ornithine carbamoyltransferase 105 c3o8nA_ not modelled 34.5 20 PDB header:transferase Chain: A: PDB Molecule:6-phosphofructokinase, muscle type; PDBTitle: structure of phosphofructokinase from rabbit skeletal muscle 106 c2ixaA_ not modelled 34.1 24 PDB header:hydrolase Chain: A: PDB Molecule:alpha-n-acetylgalactosaminidase; PDBTitle: a-zyme, n-acetylgalactosaminidase 107 d1emsa2 not modelled 33.6 22 Fold:Carbon-nitrogen hydrolase Superfamily:Carbon-nitrogen hydrolase Family:Nitrilase 108 d1h3fa1 not modelled 33.3 23 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 109 c3prhB_ not modelled 33.2 9 PDB header:ligase Chain: B: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: tryptophanyl-trna synthetase val144pro mutant from b. subtilis 110 d1zh8a1 not modelled 33.2 16 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 111 d2p10a1 not modelled 33.0 20 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Mll9387-like 112 c3m2tA_ not modelled 32.9 17 PDB header:oxidoreductase Chain: A: PDB Molecule:probable dehydrogenase; PDBTitle: the crystal structure of dehydrogenase from chromobacterium2 violaceum 113 c3hzrD_ not modelled 32.0 12 PDB header:ligase Chain: D: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: tryptophanyl-trna synthetase homolog from entamoeba histolytica 114 c3lqkA_ not modelled 31.7 16 PDB header:oxidoreductase Chain: A: PDB Molecule:dipicolinate synthase subunit b; PDBTitle: crystal structure of dipicolinate synthase subunit b from bacillus2 halodurans c 115 c3n9iA_ not modelled 30.2 15 PDB header:ligase Chain: A: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: crystal structure of tryptophanyl-trna synthetase from yersinia pestis2 co92 116 d2ex4a1 not modelled 28.8 11 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:AD-003 protein-like 117 c3iwpK_ not modelled 28.5 19 PDB header:metal binding protein Chain: K: PDB Molecule:copper homeostasis protein cutc homolog; PDBTitle: crystal structure of human copper homeostasis protein cutc 118 d1j6ua2 not modelled 27.9 18 Fold:MurD-like peptide ligases, peptide-binding domain Superfamily:MurD-like peptide ligases, peptide-binding domain Family:MurCDEF C-terminal domain 119 c2dlcX_ not modelled 26.8 13 PDB header:ligase/trna Chain: X: PDB Molecule:tyrosyl-trna synthetase, cytoplasmic; PDBTitle: crystal structure of the ternary complex of yeast tyrosyl-trna2 synthetase 120 d1jila_ not modelled 26.3 25 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0