PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c2cycB_

Fold library id	PDB Header	Molecule	Title
c2cycB_	PDB header: ligase	Chain: B: PDB Molecule: tyrosyl-trna synthetase;	PDBTitle: crystal structure of tyrosyl-trna synthetase complexed with2 l-tyrosine from pyrococcus horikoshii

Links to external resources
Added to library: Tue Mar 16 14:28:01 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence M D I E E R I N L V L K K P T E E V L T V E N L R H L F E I G A P L Q H Y I G F E I S G Y I H L G T G L M A G A K I A D F Q K A G I K T R V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S T T T T T
B
S
B T T
B

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence F L A D W H S W I N D K L G G D L E V I Q E V A L K Y F K V G M E K S I E V M G G D P K K V E F V L A S E I L E K G D Y W Q T V I D I S K N

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T G G G G
T T T
G G G S T T
T T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence V T L S R V M R S I T I M G R Q M G E A I D F A K L I Y P M M Q V A D I F Y Q G V T I A H A G M D Q R K A H V I A I E V A Q K L R Y H P I V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
T T G G G G T
T T
T T T
S G G G G G G
S S S

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280

Sequence H E G E K L K P V A V H H H L L L G L Q E P P K W P I E S E E E F K E I K A Q M K M S K S K P Y S A V F I H D S P E E I R Q K L R K A F C P

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T
B
S S
S S S S
S B G G G S
G G G S
B T T
S

. . . . . . . . . 290 . . . . . . . . . 300 . . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 . . . . . . . . . 350

Sequence A R E V R Y N P V L D W V E Y I I F R E E P T E F T V H R P A K F G G D V T Y T T F E E L K R D F A E G K L H P L D L K N A V A E Y L I N L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T
S S
T T T S S S S
G G G T
S S T T S S

. . . . . . . . . 360 . . . . . . . . . 370 . .

Sequence L E P I R R Y F E K H P E P L E L M R S V Y

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T S

Download: PDB structure FASTA sequence
Hidden Markov model

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	M	D	I	E	E	R	I	N	L	V	L	K	K	P	T	E	E	V	L	T	V	E	N	L	R	H	L	F	E	I	G	A	P	L	Q	H	Y	I	G	F	E	I	S	G	Y	I	H	L	G	T	G	L	M	A	G	A	K	I	A	D	F	Q	K	A	G	I	K	T	R	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)												S	T	T						T										T	T				B									S			B																	T	T		B
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	F	L	A	D	W	H	S	W	I	N	D	K	L	G	G	D	L	E	V	I	Q	E	V	A	L	K	Y	F	K	V	G	M	E	K	S	I	E	V	M	G	G	D	P	K	K	V	E	F	V	L	A	S	E	I	L	E	K	G	D	Y	W	Q	T	V	I	D	I	S	K	N
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)										T	T	G	G	G	G												T												T	T			G	G	G	S					T					T													T	T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	V	T	L	S	R	V	M	R	S	I	T	I	M	G	R	Q	M	G	E	A	I	D	F	A	K	L	I	Y	P	M	M	Q	V	A	D	I	F	Y	Q	G	V	T	I	A	H	A	G	M	D	Q	R	K	A	H	V	I	A	I	E	V	A	Q	K	L	R	Y	H	P	I	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S							T	T	G	G	G	G	T					T	T			T																T	T		S						G	G	G											G	G	G		S	S	S
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280
Sequence	H	E	G	E	K	L	K	P	V	A	V	H	H	H	L	L	L	G	L	Q	E	P	P	K	W	P	I	E	S	E	E	E	F	K	E	I	K	A	Q	M	K	M	S	K	S	K	P	Y	S	A	V	F	I	H	D	S	P	E	E	I	R	Q	K	L	R	K	A	F	C	P
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)		T	T														B		S	S			S	S	S	S			S												B	G	G	G	S		G	G	G	S		B	T	T													S
	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350
Sequence	A	R	E	V	R	Y	N	P	V	L	D	W	V	E	Y	I	I	F	R	E	E	P	T	E	F	T	V	H	R	P	A	K	F	G	G	D	V	T	Y	T	T	F	E	E	L	K	R	D	F	A	E	G	K	L	H	P	L	D	L	K	N	A	V	A	E	Y	L	I	N	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T	T			S	S										T	T	T	S	S	S	S									G	G	G	T						S	S										T	T	S	S
	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.
Sequence	L	E	P	I	R	R	Y	F	E	K	H	P	E	P	L	E	L	M	R	S	V	Y
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T										S