Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionO01325
DateFri May 3 21:21:05 BST 2013
Unique Job IDb5e94112012ead56

Summary 

Top model
Image coloured by rainbow N → C terminus
Model dimensions (Å):X:63.804 Y:72.941 Z:60.125
Model (left) based on template c2fo0A_
Top template information
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase abl1 (1b isoform);
PDBTitle: organization of the sh3-sh2 unit in active and inactive forms of the2 c-abl tyrosine kinase
Confidence and coverage
Confidence:100.0% Coverage: 93%
443 residues ( 93% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MLSASRGNRRHKDRSEVETAVRGPDLLLKATDETSSDGASTSLSKSVEESAPNKDKSNSS
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Disorder  ???????????????????????








???????????


?
???????????
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   .........70.........80.........90.........100.........110.........120
Sequence  LVKSHHVLKIKLKKITNWSGCSGALLDDEPFYHGYMSREESEKLVRSQGEFLLRKTELTK
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Disorder 

????????





???????

































???
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   .........130.........140.........150.........160.........170.........180
Sequence  RGEVVVLSVFWDEGVHHLVVEKANNGLYYLKEFCFENISDLVRYHHQTRASVYKSGIKLF
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Disorder  ?













































????????




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   .........190.........200.........210.........220.........230.........240
Sequence  SWVVREEWQLYHEQINLGKKLGNGEFGEVFQGVLSVGIFTNDVEVAVKTMKGSKVTADER
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Disorder 
?


































??











?
???



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   .........250.........260.........270.........280.........290.........300
Sequence  ITFLREANLMLKLNHKYVVRLYGVATQQEPIMIVMELCSGGCLKSRIEKKDEQLSDVLKR
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??????




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   .........310.........320.........330.........340.........350.........360
Sequence  KYCKQIAKGMRYLEKKQVIHRDLAARNVLLDKSDNCKISDFGLSLFGKLHKEQKLMKVPI
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?
?
?
??




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   .........370.........380.........390.........400.........410.........420
Sequence  RWLAPETLLKGIYSSKSDVWSFGVVMFEVFSGEYPYADVKVLKELRRKVAHENLRLKPPS
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?????????
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   .........430.........440.........450.........460.........470....
Sequence  DMPTDDAKVMEMCFEPVDNRATFVQVCNRYKDLTSPLPTWNGIANKLIGIGSAV
Secondary structure 

























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Disorder 
?


















?













??????????????????
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Confidence Key
High(9)                    Low (0)
?Disordered ( 25%)
Alpha helix ( 27%)
Beta strand ( 22%)

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 2fo0 chain A

3D model

Region: 12 - 467
Aligned: 443
Modelled: 456
Confidence: 100.0%
Identity: 26%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase abl1 (1b isoform);
PDBTitle: organization of the sh3-sh2 unit in active and inactive forms of the2 c-abl tyrosine kinase

Phyre2

PDB 1opl chain A

3D model

Region: 23 - 468
Aligned: 433
Modelled: 446
Confidence: 100.0%
Identity: 27%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase;
PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase

Phyre2

PDB 1y57 chain A

3D model

Region: 25 - 453
Aligned: 417
Modelled: 426
Confidence: 100.0%
Identity: 29%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor

Phyre2

PDB 2h8h chain A

3D model

Region: 26 - 461
Aligned: 424
Modelled: 436
Confidence: 100.0%
Identity: 29%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: src kinase in complex with a quinazoline inhibitor

Phyre2

PDB 1k9a chain B

3D model

Region: 17 - 453
Aligned: 416
Modelled: 431
Confidence: 100.0%
Identity: 28%
PDB header:transferase
Chain: B: PDB Molecule:carboxyl-terminal src kinase;
PDBTitle: crystal structure analysis of full-length carboxyl-terminal2 src kinase at 2.5 a resolution

Phyre2

PDB 2c0i chain A

3D model

Region: 26 - 461
Aligned: 412
Modelled: 432
Confidence: 100.0%
Identity: 27%
PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase hck;
PDBTitle: src family kinase hck with bound inhibitor a-420983

Phyre2

PDB 4fl2 chain A

3D model

Region: 87 - 453
Aligned: 359
Modelled: 364
Confidence: 100.0%
Identity: 33%
PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase syk;
PDBTitle: structural and biophysical characterization of the syk activation2 switch

Phyre2

PDB 2ozo chain A

3D model

Region: 87 - 472
Aligned: 362
Modelled: 386
Confidence: 100.0%
Identity: 33%
PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase zap-70;
PDBTitle: autoinhibited intact human zap-70

Phyre2

PDB 3cbl chain A

3D model

Region: 79 - 455
Aligned: 348
Modelled: 363
Confidence: 100.0%
Identity: 34%
PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fes/fps;
PDBTitle: crystal structure of human feline sarcoma viral oncogene homologue (v-2 fes) in complex with staurosporine and a consensus peptide

Phyre2

PDB 2j0k chain B

3D model

Region: 187 - 454
Aligned: 252
Modelled: 268
Confidence: 100.0%
Identity: 35%
PDB header:transferase
Chain: B: PDB Molecule:focal adhesion kinase 1;
PDBTitle: crystal structure of a fragment of focal adhesion kinase2 containing the ferm and kinase domains.

Phyre2

PDB 4im2 chain A

3D model

Region: 190 - 456
Aligned: 242
Modelled: 251
Confidence: 100.0%
Identity: 22%
PDB header:transferase/transferase inhibitor
Chain: A: PDB Molecule:serine/threonine-protein kinase tbk1;
PDBTitle: structure of tank-binding kinase 1

Phyre2

PDB 3qa8 chain H

3D model

Region: 196 - 443
Aligned: 243
Modelled: 248
Confidence: 100.0%
Identity: 25%
PDB header:immune system, signaling protein
Chain: H: PDB Molecule:mgc80376 protein;
PDBTitle: crystal structure of inhibitor of kappa b kinase beta

Phyre2

PDB 3qa8 chain A

3D model

Region: 196 - 442
Aligned: 242
Modelled: 247
Confidence: 100.0%
Identity: 26%
PDB header:immune system, signaling protein
Chain: A: PDB Molecule:mgc80376 protein;
PDBTitle: crystal structure of inhibitor of kappa b kinase beta

Phyre2

PDB 3nyo chain B

3D model

Region: 186 - 449
Aligned: 259
Modelled: 264
Confidence: 100.0%
Identity: 22%
PDB header:transferase
Chain: B: PDB Molecule:g protein-coupled receptor kinase 6;
PDBTitle: crystal structure of g protein-coupled receptor kinase 6 in complex2 with amp

Phyre2

PDB 2acx chain B

3D model

Region: 186 - 449
Aligned: 258
Modelled: 264
Confidence: 100.0%
Identity: 22%
PDB header:transferase
Chain: B: PDB Molecule:g protein-coupled receptor kinase 6;
PDBTitle: crystal structure of g protein coupled receptor kinase 6 bound to2 amppnp

Phyre2

PDB 3pfq chain A

3D model

Region: 188 - 449
Aligned: 255
Modelled: 262
Confidence: 100.0%
Identity: 24%
PDB header:transferase
Chain: A: PDB Molecule:protein kinase c beta type;
PDBTitle: crystal structure and allosteric activation of protein kinase c beta2 ii

Phyre2

PDB 3zzw chain A

3D model

Region: 189 - 453
Aligned: 263
Modelled: 265
Confidence: 100.0%
Identity: 32%
PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase transmembrane receptor ror2;
PDBTitle: crystal structure of the kinase domain of ror2

Phyre2

PDB 1opj chain A

3D model

Region: 186 - 467
Aligned: 274
Modelled: 279
Confidence: 100.0%
Identity: 32%
Fold: Protein kinase-like (PK-like)
Superfamily: Protein kinase-like (PK-like)
Family: Protein kinases, catalytic subunit

Phyre2

PDB 1qcf chain A domain 3

3D model

Region: 181 - 461
Aligned: 271
Modelled: 281
Confidence: 100.0%
Identity: 32%
Fold: Protein kinase-like (PK-like)
Superfamily: Protein kinase-like (PK-like)
Family: Protein kinases, catalytic subunit

Phyre2

PDB 3g0e chain A

3D model

Region: 186 - 453
Aligned: 267
Modelled: 268
Confidence: 100.0%
Identity: 31%
PDB header:transferase
Chain: A: PDB Molecule:mast/stem cell growth factor receptor;
PDBTitle: kit kinase domain in complex with sunitinib

Phyre2
1

c2fo0A_
2

c1oplA_
3

c1y57A_
4

c2h8hA_
5

c1k9aB_
6

c2c0iA_
7

c4fl2A_
8

c2ozoA_
9

c3cblA_
10

c2j0kB_
11

c4im2A_
12

c3qa8H_
13

c3qa8A_
14

c3nyoB_
15

c2acxB_
16

c3pfqA_
17

c3zzwA_
18

d1opja_
19

d1qcfa3
20

c3g0eA_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c2fo0A_



100.0 26 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase abl1 (1b isoform);
PDBTitle: organization of the sh3-sh2 unit in active and inactive forms of the2 c-abl tyrosine kinase
2c1oplA_



100.0 27 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase;
PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase
3c1y57A_



100.0 29 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor
4c2h8hA_



100.0 29 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src;
PDBTitle: src kinase in complex with a quinazoline inhibitor
5c1k9aB_



100.0 28 PDB header:transferase
Chain: B: PDB Molecule:carboxyl-terminal src kinase;
PDBTitle: crystal structure analysis of full-length carboxyl-terminal2 src kinase at 2.5 a resolution
6c2c0iA_



100.0 27 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase hck;
PDBTitle: src family kinase hck with bound inhibitor a-420983
7c4fl2A_



100.0 33 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase syk;
PDBTitle: structural and biophysical characterization of the syk activation2 switch
8c2ozoA_



100.0 33 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase zap-70;
PDBTitle: autoinhibited intact human zap-70
9c3cblA_



100.0 34 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase fes/fps;
PDBTitle: crystal structure of human feline sarcoma viral oncogene homologue (v-2 fes) in complex with staurosporine and a consensus peptide
10c2j0kB_



100.0 35 PDB header:transferase
Chain: B: PDB Molecule:focal adhesion kinase 1;
PDBTitle: crystal structure of a fragment of focal adhesion kinase2 containing the ferm and kinase domains.
11c4im2A_



100.0 22 PDB header:transferase/transferase inhibitor
Chain: A: PDB Molecule:serine/threonine-protein kinase tbk1;
PDBTitle: structure of tank-binding kinase 1
12c3qa8H_



100.0 25 PDB header:immune system, signaling protein
Chain: H: PDB Molecule:mgc80376 protein;
PDBTitle: crystal structure of inhibitor of kappa b kinase beta
13c3qa8A_



100.0 26 PDB header:immune system, signaling protein
Chain: A: PDB Molecule:mgc80376 protein;
PDBTitle: crystal structure of inhibitor of kappa b kinase beta
14c3nyoB_



100.0 22 PDB header:transferase
Chain: B: PDB Molecule:g protein-coupled receptor kinase 6;
PDBTitle: crystal structure of g protein-coupled receptor kinase 6 in complex2 with amp
15c2acxB_



100.0 22 PDB header:transferase
Chain: B: PDB Molecule:g protein-coupled receptor kinase 6;
PDBTitle: crystal structure of g protein coupled receptor kinase 6 bound to2 amppnp
16c3pfqA_



100.0 24 PDB header:transferase
Chain: A: PDB Molecule:protein kinase c beta type;
PDBTitle: crystal structure and allosteric activation of protein kinase c beta2 ii
17c3zzwA_



100.0 32 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase transmembrane receptor ror2;
PDBTitle: crystal structure of the kinase domain of ror2
18d1opja_



100.0 32 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
19d1qcfa3



100.0 32 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
20c3g0eA_



100.0 31 PDB header:transferase
Chain: A: PDB Molecule:mast/stem cell growth factor receptor;
PDBTitle: kit kinase domain in complex with sunitinib
21c1ym7C_



not modelled 100.0 23 PDB header:transferase
Chain: C: PDB Molecule:beta-adrenergic receptor kinase 1;
PDBTitle: g protein-coupled receptor kinase 2 (grk2)
22c2vwiC_



not modelled 100.0 25 PDB header:transferase
Chain: C: PDB Molecule:serine/threonine-protein kinase osr1;
PDBTitle: structure of the osr1 kinase, a hypertension drug target
23c3c4yA_



not modelled 100.0 22 PDB header:transferase
Chain: A: PDB Molecule:rhodopsin kinase;
PDBTitle: crystal structure of apo form of g protein coupled receptor kinase 12 at 7.51a
24c1koaA_



not modelled 100.0 21 PDB header:kinase
Chain: A: PDB Molecule:twitchin;
PDBTitle: twitchin kinase fragment (c.elegans), autoregulated protein2 kinase and immunoglobulin domains
25c3c4wB_



not modelled 100.0 23 PDB header:transferase
Chain: B: PDB Molecule:rhodopsin kinase;
PDBTitle: crystal structure of g protein coupled receptor kinase 1 bound to atp2 and magnesium chloride at 2.7a
26c3ckxA_



not modelled 100.0 23 PDB header:transferase
Chain: A: PDB Molecule:serine/threonine-protein kinase 24;
PDBTitle: crystal structure of sterile 20-like kinase 3 (mst3, stk24)2 in complex with staurosporine
27d1lufa_



not modelled 100.0 28 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
28c1lufA_



not modelled 100.0 28 PDB header:transferase
Chain: A: PDB Molecule:muscle-specific tyrosine kinase receptor musk;
PDBTitle: crystal structure of the musk tyrosine kinase: insights2 into receptor autoregulation
29d1qpca_



not modelled 100.0 32 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
30c3dpkA_



not modelled 100.0 31 PDB header:transferase
Chain: A: PDB Molecule:macrophage colony-stimulating factor 1 receptor;
PDBTitle: cfms tyrosine kinase in complex with a pyridopyrimidinone2 inhibitor
31c2ivsA_



not modelled 100.0 28 PDB header:transferase
Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase receptor
PDBTitle: crystal structure of non-phosphorylated ret tyrosine kinase2 domain
32d1u59a_



not modelled 100.0 33 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
33c2c30A_



not modelled 100.0 24 PDB header:transferase
Chain: A: PDB Molecule:serine/threonine-protein kinase pak 6;
PDBTitle: crystal structure of the human p21-activated kinase 6
34c2pvfA_



not modelled 100.0 30 PDB header:transferase
Chain: A: PDB Molecule:fibroblast growth factor receptor 2;
PDBTitle: crystal structure of tyrosine phosphorylated activated fgf receptor 22 (fgfr2) kinase domain in complex with atp analog and substrate3 peptide
35d1k2pa_



not modelled 100.0 35 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
36d2j4za1



not modelled 100.0 23 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
37c3soaA_



not modelled 100.0 23 PDB header:transferase/transferase inhibitor
Chain: A: PDB Molecule:calcium/calmodulin-dependent protein kinase type ii subunit
PDBTitle: full-length human camkii
38c3q5iA_



not modelled 100.0 25 PDB header:transferase
Chain: A: PDB Molecule:protein kinase;
PDBTitle: crystal structure of pbanka_031420
39c2psqA_



not modelled 100.0 30 PDB header:transferase
Chain: A: PDB Molecule:fibroblast growth factor receptor 2;
PDBTitle: crystal structure of unphosphorylated unactivated wild type2 fgf receptor 2 (fgfr2) kinase domain
40d2psqa1



not modelled 100.0 30 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
41c3lxkA_



not modelled 100.0 29 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase jak3;
PDBTitle: structural and thermodynamic characterization of the tyk2 and jak32 kinase domains in complex with cp-690550 and cmp-6
42d3bu3a1



not modelled 100.0 33 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
43d1uwha_



not modelled 100.0 29 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
44c3tkuB_



not modelled 100.0 20 PDB header:transferase/transferase inhibitor
Chain: B: PDB Molecule:serine/threonine-protein kinase mrck beta;
PDBTitle: mrck beta in complex with fasudil
45d1t46a_



not modelled 100.0 30 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
46c4aojA_



not modelled 100.0 33 PDB header:transferase
Chain: A: PDB Molecule:high affinity nerve growth factor receptor;
PDBTitle: human trka in complex with the inhibitor az-23
47c4dn5A_



not modelled 100.0 24 PDB header:transferase
Chain: A: PDB Molecule:mitogen-activated protein kinase kinase kinase 14;
PDBTitle: crystal structure of nf-kb-inducing kinase (nik)
48c3d4qA_



not modelled 100.0 29 PDB header:transferase
Chain: A: PDB Molecule:b-raf proto-oncogene serine/threonine-protein kinase;
PDBTitle: pyrazole-based inhibitors of b-raf kinase
49c2bujA_



not modelled 100.0 21 PDB header:transferase
Chain: A: PDB Molecule:serine/threonine-protein kinase 16;
PDBTitle: crystal structure of the human serine-threonine kinase 162 in complex with staurosporine
50c4fijA_



not modelled 100.0 24 PDB header:transferase
Chain: A: PDB Molecule:serine/threonine-protein kinase pak 4;
PDBTitle: catalytic domain of human pak4
51c3kulB_



not modelled 100.0 33 PDB header:transferase
Chain: B: PDB Molecule:ephrin type-a receptor 8;
PDBTitle: kinase domain of human ephrin type-a receptor 8 (epha8)
52c4ebwA_



not modelled 100.0 33 PDB header:transferase/transferase inhibitor
Chain: A: PDB Molecule:focal adhesion kinase 1;
PDBTitle: structure of focal adhesion kinase catalytic domain in complex with2 novel allosteric inhibitor
53c4eutA_



not modelled 100.0 20 PDB header:transferase/transferase inhibitor
Chain: A: PDB Molecule:serine/threonine-protein kinase tbk1;
PDBTitle: structure of bx-795 complexed with unphosphorylated human tbk1 kinase-2 uld domain
54c3plsA_



not modelled 100.0 26 PDB header:transferase
Chain: A: PDB Molecule:macrophage-stimulating protein receptor;
PDBTitle: ron in complex with ligand amp-pnp
55d1yhwa1



not modelled 100.0 22 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
56d1phka_



not modelled 100.0 24 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
57d1p4oa_



not modelled 100.0 33 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
58c3lvpD_



not modelled 100.0 33 PDB header:transferase
Chain: D: PDB Molecule:insulin-like growth factor 1 receptor;
PDBTitle: crystal structure of bisphosphorylated igf1-r kinase domain (2p) in2 complex with a bis-azaindole inhibitor
59c4fieB_



not modelled 100.0 23 PDB header:transferase
Chain: B: PDB Molecule:serine/threonine-protein kinase pak 4;
PDBTitle: full-length human pak4
60c2jamB_



not modelled 100.0 24 PDB header:transferase
Chain: B: PDB Molecule:calcium/calmodulin-dependent protein kinase type
PDBTitle: crystal structure of human calmodulin-dependent protein2 kinase i g
61c1yvjA_



not modelled 100.0 29 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase jak3;
PDBTitle: crystal structure of the jak3 kinase domain in complex with2 a staurosporine analogue
62c3vw6B_



not modelled 100.0 29 PDB header:transferase/transferase inhibitor
Chain: B: PDB Molecule:mitogen-activated protein kinase kinase kinase 5;
PDBTitle: crystal structure of human apoptosis signal-regulating kinase 1 (ask1)2 with imidazopyridine inhibitor
63d1mp8a_



not modelled 100.0 32 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
64c2a1aB_



not modelled 100.0 23 PDB header:protein synthesis/transferase
Chain: B: PDB Molecule:interferon-induced, double-stranded rna-activated protein
PDBTitle: pkr kinase domain-eif2alpha complex
65d1fmka3



not modelled 100.0 32 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
66c3dfaA_



not modelled 100.0 29 PDB header:transferase
Chain: A: PDB Molecule:calcium-dependent protein kinase cgd3_920;
PDBTitle: crystal structure of kinase domain of calcium-dependent protein kinase2 cgd3_920 from cryptosporidium parvum
67c3eygA_



not modelled 100.0 28 PDB header:transferase
Chain: A: PDB Molecule:tyrosine-protein kinase;
PDBTitle: crystal structures of jak1 and jak2 inhibitor complexes
68c2wtkC_



not modelled 100.0 23 PDB header:transferase/metal-binding protein
Chain: C: PDB Molecule:serine/threonine-protein kinase 11;
PDBTitle: structure of the heterotrimeric lkb1-stradalpha-mo25alpha2 complex
69d1fgka_



not modelled 100.0 31 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
70c3lijA_



not modelled 100.0 31 PDB header:transferase
Chain: A: PDB Molecule:calcium/calmodulin dependent protein kinase with
PDBTitle: crystal structure of full length cpcdpk3 (cgd5_820) in2 complex with ca2+ and amppnp
71c2clqA_



not modelled 100.0 28 PDB header:transferase
Chain: A: PDB Molecule:mitogen-activated protein kinase kinase kinase 5;
PDBTitle: structure of mitogen-activated protein kinase kinase kinase2 5
72c2bmcD_



not modelled 100.0 24 PDB header:transferase
Chain: D: PDB Molecule:serine threonine-protein kinase 6;
PDBTitle: aurora-2 t287d t288d complexed with pha-680632
73c3l9pA_



not modelled 100.0 32 PDB header:transferase
Chain: A: PDB Molecule:anaplastic lymphoma kinase;
PDBTitle: crystal structure of the anaplastic lymphoma kinase catalytic domain
74d1jpaa_



not modelled 100.0 32 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
75c2w1iB_



not modelled 100.0 30 PDB header:transferase
Chain: B: PDB Molecule:jak2;
PDBTitle: structure determination of aurora kinase in complex with2 inhibitor
76c3fupB_



not modelled 100.0 30 PDB header:transferase
Chain: B: PDB Molecule:tyrosine-protein kinase jak2;
PDBTitle: crystal structures of jak1 and jak2 inhibitor complexes
77c3lxnA_



not modelled 100.0 24 PDB header:transferase
Chain: A: PDB Molecule:non-receptor tyrosine-protein kinase tyk2;
PDBTitle: structural and thermodynamic characterization of the tyk2 and jak32 kinase domains in complex with cp-690550 and cmp-6
78d1sm2a_



not modelled 100.0 36 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
79c3cc6A_



not modelled 100.0 30 PDB header:transferase
Chain: A: PDB Molecule:protein tyrosine kinase 2 beta;
PDBTitle: crystal structure of kinase domain of protein tyrosine kinase 2 beta2 (ptk2b)
80c2y7jB_



not modelled 100.0 23 PDB header:transferase
Chain: B: PDB Molecule:phosphorylase b kinase gamma catalytic chain,
PDBTitle: structure of human phosphorylase kinase, gamma 2
81c2bdwB_



not modelled 100.0 26 PDB header:transferase
Chain: B: PDB Molecule:hypothetical protein k11e8.1d;
PDBTitle: crystal structure of the auto-inhibited kinase domain of2 calcium/calmodulin activated kinase ii
82d1mqba_



not modelled 100.0 33 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
83c3v5qB_



not modelled 100.0 28 PDB header:transferase/transferase inhibitor
Chain: B: PDB Molecule:nt-3 growth factor receptor;
PDBTitle: discovery of a selective trk inhibitor with efficacy in rodent cancer2 tumor models
84d1xbba_



not modelled 100.0 34 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
85d2jfla1



not modelled 100.0 25 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
86c2qg5D_



not modelled 100.0 26 PDB header:transferase
Chain: D: PDB Molecule:calcium/calmodulin-dependent protein kinase;
PDBTitle: cryptosporidium parvum calcium dependent protein kinase cgd7_1840
87c2a27B_



not modelled 100.0 24 PDB header:transferase
Chain: B: PDB Molecule:death-associated protein kinase 2;
PDBTitle: human drp-1 kinase, w305s s308a d40 mutant, crystal form with 82 monomers in the asymmetric unit
88c2j51A_



not modelled 100.0 24 PDB header:transferase
Chain: A: PDB Molecule:ste20-like serine/threonine-protein kinase;
PDBTitle: crystal structure of human ste20-like kinase bound to 5-2 amino-3-((4-(aminosulfonyl)phenyl)amino)-n-(2,6-3 difluorophenyl)-1h-1,2,4-triazole-1-carbothioamide
89c3an0A_



not modelled 100.0 21 PDB header:transferase/transferase inhibitor
Chain: A: PDB Molecule:dual specificity mitogen-activated protein kinase kinase 6;
PDBTitle: crystal structure of non-phosphorylated map2k6 as a putative auto2 inhibition state
90d1jksa_



not modelled 100.0 23 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
91c2wqmA_



not modelled 100.0 24 PDB header:transferase
Chain: A: PDB Molecule:serine/threonine-protein kinase nek7;
PDBTitle: structure of apo human nek7
92c3d9vA_



not modelled 100.0 22 PDB header:transferase
Chain: A: PDB Molecule:rho-associated protein kinase 1;
PDBTitle: crystal structure of rock i bound to h-1152p a di-2 methylated variant of fasudil
93c3fbvL_



not modelled 100.0 29 PDB header:transferase, hydrolase
Chain: L: PDB Molecule:serine/threonine-protein kinase/endoribonuclease ire1;
PDBTitle: crystal structure of the oligomer formed by the kinase-ribonuclease2 domain of ire1
94c3p23B_



not modelled 100.0 23 PDB header:hydrolase, transferase
Chain: B: PDB Molecule:serine/threonine-protein kinase/endoribonuclease ire1;
PDBTitle: crystal structure of the human kinase and rnase domains in complex2 with adp
95c1mruB_



not modelled 100.0 23 PDB header:transferase
Chain: B: PDB Molecule:probable serine/threonine-protein kinase pknb;
PDBTitle: intracellular ser/thr protein kinase domain of2 mycobacterium tuberculosis pknb.
96d1koba_



not modelled 100.0 21 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
97c2cgvA_



not modelled 100.0 29 PDB header:transferase
Chain: A: PDB Molecule:serine/threonine-protein kinase chk1;
PDBTitle: identification of chemically diverse chk1 inhibitors by2 receptor-based virtual screening
98c3hztA_



not modelled 100.0 29 PDB header:transferase
Chain: A: PDB Molecule:calcium-dependent protein kinase 3;
PDBTitle: crystal structure of toxoplasma gondii cdpk3, tgme49_105860
99d1o6ya_



not modelled 100.0 23 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
100c3p86B_



not modelled 100.0 30 PDB header:transferase
Chain: B: PDB Molecule:serine/threonine-protein kinase ctr1;
PDBTitle: crystal structure of ctr1 kinase domain mutant d676n in complex with2 staurosporine
101d1fvra_



not modelled 100.0 31 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
102c2chlA_



not modelled 100.0 20 PDB header:transferase
Chain: A: PDB Molecule:casein kinase i isoform gamma-3;
PDBTitle: structure of casein kinase 1 gamma 3
103d1xjda_



not modelled 100.0 25 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
104c1xjdA_



not modelled 100.0 25 PDB header:transferase
Chain: A: PDB Molecule:protein kinase c, theta type;
PDBTitle: crystal structure of pkc-theta complexed with staurosporine2 at 2a resolution
105c4eqmE_



not modelled 100.0 22 PDB header:transferase
Chain: E: PDB Molecule:protein kinase;
PDBTitle: structural analysis of staphylococcus aureus serine/threonine kinase2 pknb
106c4hzsA_



not modelled 100.0 34 PDB header:transferase
Chain: A: PDB Molecule:activated cdc42 kinase 1;
PDBTitle: crystal structure of ack1 kinase domain with c-terminal sh3 domain
107c3sxrA_



not modelled 100.0 35 PDB header:transferase/transferase inhibitor
Chain: A: PDB Molecule:cytoplasmic tyrosine-protein kinase bmx;
PDBTitle: crystal structure of bmx non-receptor tyrosine kinase complex with2 dasatinib
108c2x4fA_



not modelled 100.0 22 PDB header:transferase
Chain: A: PDB Molecule:myosin light chain kinase family member 4;
PDBTitle: the crystal structure of the human myosin light chain2 kinase loc340156.
109c2vd5A_



not modelled 100.0 22 PDB header:transferase
Chain: A: PDB Molecule:dmpk protein;
PDBTitle: structure of human myotonic dystrophy protein kinase in2 complex with the bisindoylmaleide inhibitor bim viii
110d1nvra_



not modelled 100.0 29 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
111c2ya9A_



not modelled 100.0 24 PDB header:transferase
Chain: A: PDB Molecule:death-associated protein kinase 2;
PDBTitle: crystal structure of the autoinhibited form of mouse dapk2
112d1koaa2



not modelled 100.0 21 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
113d1xkka_



not modelled 100.0 31 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
114c1xkkA_



not modelled 100.0 31 PDB header:transferase
Chain: A: PDB Molecule:epidermal growth factor receptor;
PDBTitle: egfr kinase domain complexed with a quinazoline inhibitor-2 gw572016
115c2pziA_



not modelled 100.0 16 PDB header:transferase
Chain: A: PDB Molecule:probable serine/threonine-protein kinase pkng;
PDBTitle: crystal structure of protein kinase pkng from mycobacterium2 tuberculosis in complex with tetrahydrobenzothiophene ax20017
116d1ckia_



not modelled 100.0 19 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
117c3sv0A_



not modelled 100.0 20 PDB header:transferase
Chain: A: PDB Molecule:casein kinase i-like;
PDBTitle: crystal structure of casein kinase-1 like protein in plant
118d1rjba_



not modelled 100.0 32 Fold:Protein kinase-like (PK-like)
Superfamily:Protein kinase-like (PK-like)
Family:Protein kinases, catalytic subunit
119c2qobA_



not modelled 100.0 34 PDB header:transferase
Chain: A: PDB Molecule:ephrin receptor;
PDBTitle: human epha3 kinase domain, base structure
120c1kobB_



not modelled 100.0 22 PDB header:kinase
Chain: B: PDB Molecule:twitchin;
PDBTitle: twitchin kinase fragment (aplysia), autoregulated protein2 kinase domain

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite